No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

MitoPrime Ingredients & Drug Interactions

by XYMOGEN

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

MitoPrime is a dietary supplement by XYMOGEN with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, healthy aging and longevity, cellular protection.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of MitoPrime by XYMOGEN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

MitoPrime is a single-ingredient supplement containing ergothioneine, a naturally occurring amino acid found in mushrooms and some foods. The product also contains several inactive ingredients — microcrystalline cellulose, dicalcium phosphate, hypromellose, water, ascorbyl palmitate, and silica — that serve as fillers and stabilizers in the capsule.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Ergothioneine product and its label doesn't state a use — see Ergothioneine's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for ergothioneine is not yet established. For coronary heart disease and joint pain — the two conditions we have data on — there's insufficient reliable evidence to rate whether it works.

That doesn't mean it doesn't; it means the research so far hasn't been conclusive enough to say.

The evidence, ingredient by ingredient Ergothioneine

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ergothioneine appears well tolerated in foods and short-term studies, but how safe it is to take long-term as a supplement isn't well established yet. The safety data advises against use during pregnancy and while breastfeeding — there isn't enough research to know whether it's safe at supplement doses during these times, so it's best to skip it if you're pregnant, trying to conceive, or nursing.

Side effects, ingredient by ingredient Ergothioneine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Even so, check your exact medications with the search tool on this page and confirm with your doctor or pharmacist before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.

MitoPrime may interest you if you're curious about ergothioneine for heart or joint health, but the evidence isn't solid yet on whether it works. If you're pregnant, breastfeeding, or taking medications, talk with your doctor or pharmacist before you add it to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about MitoPrime, straight from the product label.

Brand XYMOGEN
Barcode (UPC) 722537512251
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 303758
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for MitoPrime by XYMOGEN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
722537512251
IngredientAmount% DV
MitoPrime12.5 mg--

Other ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Hypromellose, Water, Ascorbyl Palmitate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

DIRECTIONS: Take one capsule once or twice daily, or use as directed by your healthcare professional.

Precautions

Consult your healthcare professional before use.

Individuals taking medication should discuss potential interactions with their healthcare professional.

Do not use if tamper seal is damaged.

STORAGE: Keep tightly closed in a cool, dry place out of reach of children.

Formula

MitoPrime features the concentrated form of the histidine derivative L-ergothioneine produced via a proprietary fermentation-based method. Through its antioxidant and cytoprotectant mechanisms, L-ergothioneine combats oxidative stress throughout the body and provides multiple health benefits.

MitoPrime

Fermentation-Based L-Ergothioneine

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

STORAGE: Keep tightly closed in a cool, dry place out of reach of children.

Formulation

FORMULATED TO EXCLUDE: Wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, sesame, ingredients derived from genetically modified organisms (GMOs), artificial colors, and artificial sweeteners.

Vegetarian caps

Brand IP Statement(s)

S1. MitoPrime is a registered trademark of NNB Nutrition.

Xymogen Exclusive professional formulas

Copyright 2023 XYMOGEN

Seals/Symbols

Vegetarian caps

ePV (ePedigree Verification)

GMP compliant third-party verified

FDA Statement of Identity

Dietary Supplement

General Statements

Scan to learn more! This package is completely recyclable

See for yourself

MitoPrime by XYMOGEN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in MitoPrime by XYMOGEN

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

MitoPrime

No known
interactions
12.5 mg per serving Form: L-Ergothioneine

Ergothioneine is a naturally occurring amino acid–like compound (an antioxidant) found mostly in mushrooms and made by certain fungi and bacteria. Ear...

MitoPrime monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Hypromellose, Water, Ascorbyl Palmitate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

MitoPrime by XYMOGEN Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in MitoPrime. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for MitoPrime, from the product label.

XYMOGEN

See all XYMOGEN products
Name
XYMOGEN Exclusive Professional Formulas
Street Address
6900 Kingspointe Pkwy.
City
Orlando
State
FL
ZipCode
32819
Phone Number
800-647-6100
Web Address
www.xymogen.com
Pharmacist Counseling Corner

MitoPrime by XYMOGEN: Common Questions

Does MitoPrime by XYMOGEN interact with any medications?
We do not currently list a known interaction for the mapped ingredients in MitoPrime. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
MitoPrime contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is MitoPrime safe to take if I'm pregnant?
No — there isn't enough safety data on supplement doses of ergothioneine during pregnancy, so it's best avoided if you're pregnant or trying to conceive. Talk with your doctor or pharmacist about whether it's right for you.
Can I take MitoPrime while breastfeeding?
No — safety while breastfeeding hasn't been studied, so supplemental use is best avoided. Discuss it with your doctor or pharmacist if you have questions.
What does ergothioneine do?
Ergothioneine is a naturally occurring amino acid found in mushrooms and some foods. It's being studied for possible benefits to heart health and joint pain, but the evidence so far isn't conclusive enough to say whether it works for these purposes.
Does MitoPrime have side effects?
The product facts we have don't list adverse effects from trials. Ergothioneine appears well tolerated, though long-term supplement safety isn't well established yet.
Does MitoPrime contain fillers?
Yes — the capsule contains microcrystalline cellulose, dicalcium phosphate, hypromellose, ascorbyl palmitate, and silica as inactive ingredients that help stabilize and deliver the active component.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if MitoPrime is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

MitoPrime label
Go deeper

The Full Monographs Behind MitoPrime’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

MitoPrime's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ergothioneine 2 references
  1. Benson KF, Ager DM, Landes B, Aruoma OI, Jensen GS. Improvement of joint range of motion (ROM) and reduction of chronic pain after consumption of an ergothioneine-containing nutritional supplement. Prev Med. 2012;54 Suppl:S83-9. PubMed
  2. Smith E, Ottosson F, Hellstrand S, et al. Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease. Heart 2019. pii: heartjnl-2019-315485. PubMed

See these in context on the Ergothioneine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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