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Vitamin D is a fat-soluble vitamin that plays a crucial role in several bodily processes. It helps the body absorb calcium and phosphorus, which are necessary for healthy bones and teeth. It is also important for immune system function and may help to protect against certain diseases. Vitamin D is found in a variety of foods, including fatty fish, egg yolks, and fortified foods such as milk and cereal. It is also produced by the body when the skin is exposed to sunlight. Vitamin D supplements are available in a variety of forms, including tablets, capsules, and liquids. The recommended daily intake of vitamin D varies depending on age, sex, and other factors, and it is important to follow the dosage recommendations provided by a healthcare professional. There are several different forms of vitamin D available, with the two most popular being ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3).

Vitamin E is a fat-soluble vitamin found naturally in a variety of foods, including vegetable oils, nuts, seeds, and leafy green vegetables. Vitamin E is also available as a dietary supplement and is often added to skincare products. Vitamin E has many roles in the body, including protecting cells from oxidative stress and supporting immune function.

Niacin, also known as vitamin B3, is a water-soluble vitamin found in a variety of foods, including meat, poultry, fish, and fortified grains. It plays a variety of roles in the body, including in the metabolism of carbohydrates, fats, and proteins. It is also necessary for the production of energy in the body and in the synthesis of different hormones. Niacin deficiency is rare in developed countries, however, supplementation has been shown to have several positive benefits. For example, it can reduce the risk of diabetic neuropathy (i.e., nerve pain) and has been shown effective for treating some types of high cholesterol (extended-release niacin is used as a prescription drug in the United States for this purpose). There is a multitude of niacin forms available as dietary supplements, including NADH, niacinamide, and nicotinamide riboside, all with different properties.

Vitamin B12, also known as cobalamin, is a water-soluble vitamin crucial for several bodily functions. It plays a pivotal role in the formation of red blood cells, aiding in the prevention of anemia. Vitamin B12 is essential for maintaining a healthy nervous system and proper brain function, as it is involved in the synthesis of myelin, the protective sheath around nerve fibers. This vitamin is primarily found in animal-based foods such as meat, fish, dairy products, and eggs, making it important for vegetarians and vegans to consider supplementation. A deficiency in vitamin B12 can lead to neurological issues, fatigue, and cognitive impairment.

Biotin, also known as vitamin H or vitamin B7, is a water-soluble vitamin that plays a role in various metabolic processes in the body. It is necessary for the growth and maintenance of healthy skin, hair, and nails, and is also involved in the metabolism of carbohydrates, fats, and amino acids. Biotin is considered to be generally safe when consumed in the recommended daily amounts but it is important to note that consuming large amounts of biotin-containing supplements or products can cause falsely high or falsely low test results for certain laboratory tests, such as those for thyroid function, hormone levels, and certain biomarkers for certain diseases.

Selenium is an essential trace element that plays a crucial role in various physiological functions in the human body. It is often included in dietary supplements due to its antioxidant properties and its contribution to maintaining a healthy immune system. Selenium is important for thyroid function and may also have a role in protecting against certain chronic diseases. However, it's essential to note that excessive selenium intake can be harmful, so it's crucial to adhere to recommended daily allowances and consult with a healthcare professional before taking selenium supplements.

Chromium is a trace mineral that is found in small amounts in the human body. It is believed to play a role in the metabolism of carbohydrates, fats, and proteins. It is used as a dietary supplement for its purported ability to help with weight loss and blood sugar control. There is some evidence to suggest that chromium supplements may help to improve blood sugar control in people with type 2 diabetes, although the results of studies on this topic have been mixed. Some studies have found that chromium supplements can improve insulin sensitivity and reduce blood sugar levels in those with poorly controlled diabetes, while others have found no significant effects.

Magnesium is a mineral that is essential for the proper functioning of the body. It plays a role in many important physiological processes, including the contraction and relaxation of muscles, the transmission of nerve impulses, and the regulation of blood pressure. Magnesium is found in a variety of foods, including leafy green vegetables, nuts, and grains, and it is also available as a dietary supplement. There are several different forms of magnesium that are available as supplements, all of which can be used to prevent deficiency. Additionally, magnesium is purported to have several different health benefits, such as improving sleep, reducing muscle cramps, reducing anxiety, and preventing or treating migraines. Although magnesium is essential for health, magnesium-containing foods and supplements can interact with some prescription medications if used at the same time.

Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.

Creatine is an organic amine that occurs naturally in the body and is also found in certain foods, such as meat and fish. It is stored mostly in the skeletal muscles, where it is used to generate energy during physical activity. Creatine is a popular over-the-counter dietary supplement, and some evidence suggests it is effective at improving exercise performance, particularly during high-intensity activities such as weightlifting and sprinting. However, the degree to which creatine supplements may improve exercise performance can vary depending on the individual and the type of physical activity being performed Creatine is generally well-tolerated but may cause some minor side effects, such as cramping and water retention in some individuals. Long-term use has been rarely linked to kidney problems, but its use is generally regarded as safe. There are several different forms of creatine available, with the most common form being monohydrate salt. Other salt forms, including di-creatine citrate and 'pH buffered' creatine, are also available.

L-glutamine is the most abundant free amino acid in the body, produced primarily in skeletal muscle and then released into circulation. It serves vital roles in various tissues, including the immune system, gastrointestinal tract, kidneys, and liver, where it supports essential functions such as maintaining intestinal integrity, immune response, and amino acid balance. Although traditionally classified as a non-essential amino acid, during periods of severe stress, glutamine becomes conditionally essential due to the body's increased demand. It acts as a critical nitrogen and carbon transporter between organs, and while the intestinal mucosa can synthesize glutamine, this production is insufficient during times of significant physiological stress. Dietary supplements generally contain L-glutamine as it is the biologically active form of the amino acid.