Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

Pump Mango Sorbet Ingredients & Drug Interactions

by Alani Nu

Pump Mango Sorbet label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pump Mango Sorbet against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pump Mango Sorbet is a dietary supplement by Alani Nu with 5 active ingredients. Its ingredients are commonly taken for exercise performance, muscle soreness and fatigue, blood flow and circulation.Based on those ingredients, 397 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Huperzia serrata, L-Citrulline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pump Mango Sorbet by Alani Nu

Ask about any prescription or over-the-counter medication and we check it for interactions with Pump Mango Sorbet by Alani Nu — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pump Mango Sorbet by Alani Nu

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Alani Nu Pump has 5 active ingredients. L-citrulline is an amino acid that your body converts to another compound to boost blood flow and nitric oxide production — that's what helps with pumps and athletic performance.

Nitrosigine is a form of arginine bonded to silicon that works similarly. GlycerPump is a form of glycerol, which pulls fluid into muscles and may help with hydration during exercise.

Huperzia serrata (toothed clubmoss) is an herbal extract, and AstraGin is a proprietary blend meant to improve nutrient absorption. The powder also contains inactive ingredients like citric acid, malic acid, silica, natural and artificial flavors, sucralose, acesulfame potassium, beet root extract, and turmeric extract.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: pre-workout energy and athletic performance.
  • We looked for evidence on: Athletic performance, Muscle strength, endurance, exercise capacity.
  • The strongest evidence on file: Glycerol is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: L-citrulline is rated "Possibly Effective" for Athletic performance.
  • Also on file: L-citrulline is rated "Insufficient Reliable Evidence To Rate" for Muscle strength.

L-citrulline is rated possibly effective for athletic performance — the science suggests it may help, but we need more evidence. It's rated possibly ineffective for sarcopenia (age-related muscle loss), and there's insufficient evidence for cardiovascular disease, heart failure, diabetes, and Reye syndrome.

Glycerol (in GlycerPump) is rated likely effective for constipation and possibly effective for certain skin conditions, and possibly effective for athletic performance. We hold no effectiveness ratings for Huperzia serrata, Nitrosigine, or AstraGin in our data.

The evidence, ingredient by ingredient L-citrulline Glycerol Toothed Clubmoss

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-citrulline is generally well tolerated in healthy adults, though long-term safety hasn't been fully studied. The most common side effects are gastrointestinal discomfort and heartburn.

Glycerol is well tolerated in normal amounts, but larger medicinal doses can cause bloating, diarrhea, nausea, vomiting, dizziness, and headache — it can also cause dehydration concerns at high doses. Huperzia serrata may cause dizziness, nausea, and sweating; product quality varies widely.

There isn't enough safety data for L-citrulline, Glycerol, or Huperzia serrata during pregnancy, so these should be avoided. The same goes for breastfeeding — safety data is missing for all three, so supplemental use is not advised.

Side effects, ingredient by ingredient L-citrulline Glycerol Toothed Clubmoss

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Toothed Clubmoss, L-citrulline.
  • The most serious interaction on file is rated Moderate.
  • For scale: 397 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Alani Nu Pump, double-check with your pharmacist if you use blood pressure medications (antihypertensives) or erectile dysfunction drugs (PDE-5 inhibitors like sildenafil) — L-citrulline could add to their effects and lower your blood pressure too much. Also flag anticholinergic drugs (for bladder control or motion sickness) and cholinergic drugs (like donepezil for Alzheimer's) — Huperzia serrata may interfere with how they work.

We could not check Nitrosigine or AstraGin, so mention those names to your pharmacist too.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This pre-workout powder is aimed at athletes looking to boost blood flow and muscle pumps. If you take blood pressure medications, ED drugs, or medications for bladder, Alzheimer's, or Parkinson's disease, check with your pharmacist first — the interactions could affect how your drugs work.

Pregnant or breastfeeding? Skip it; there's not enough safety data.

For everyone else, talk to us before you start if you have any questions about your specific situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pump Mango Sorbet, straight from the product label.

Brand Alani Nu
Barcode (UPC) 850645008943
Net contents 11.53 Ounce(s); 327 Gram(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 321230
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pump Mango Sorbet by Alani Nu, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10.9 Gram(s)
Maximum serving Sizes:
10.9 Gram(s)
Servings per container
30
UPC/BARCODE
850645008943
IngredientAmount% DV
L-Citrulline4 Gram(s)--
Nitrosigine1.5 Gram(s)--
AstraGin50 mg--
GlycerPump2 Gram(s)--
Huperzia serrata10 mg--

Other ingredients: Citric Acid, Malic Acid, Silica, Natural & Artificial Flavors, Sucralose, Acesulfame Potassium, Beet Root Extract, Turmeric Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Mix 1 scoop in 6-8 oz of water 20-30 minutes before your workout.

Precautions

Warning: Do not consume more than one serving over 3-4 hours. Do not exceed more than 2 servings per day.

Consult a physician before use if you are nursing, lactating, have a medical condition (including but not limited to, hypertension or thyroid conditions), or taking any medication.

Not recommended for use by children under 18 years of age. Keep out of the reach of children.

Allergen Warning: Processed in a facility that also processes products containing milk, soy, wheat, egg, peanuts, tree nuts, fish and shellfish.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Gluten free Sugar free

Vegan

Stim free

Endurance Focus Pump

Formula

Mango Sorbet Naturally & Artificially Flavored

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pump Mango Sorbet by Alani Nu label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pump Mango Sorbet label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pump Mango Sorbet by Alani Nu

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size10.9 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Citrulline

Interacts with
178 drugs
4 Gram(s) per serving

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. I...

L-Citrulline monograph & interactions

Nitrosigine

1.5 Gram(s) per serving Form: Inositol-Stabilized Arginine Silicate

AstraGin

50 mg per serving Form: Astragalus membranaceus root extract, Panax notoginseng root extract

GlycerPump

No known
interactions
2 Gram(s) per serving Form: Glycerol

Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well establis...

GlycerPump monograph & interactions

Huperzia serrata

Interacts with
219 drugs
10 mg per serving Form: Huperzine

Toothed Clubmoss is a moss-like plant best known as the natural source of huperzine A, a compound studied mainly for memory and Alzheimer's disease. S...

Huperzia serrata monograph & interactions

Other (inactive) ingredients: Citric Acid, Malic Acid, Silica, Natural & Artificial Flavors, Sucralose, Acesulfame Potassium, Beet Root Extract, Turmeric Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pump Mango Sorbet by Alani Nu Drug Interactions

Want to check YOUR meds against Pump Mango Sorbet?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
397Drugs
397 Moderate

Ingredients driving the most interactions

Huperzia serrata 219
L-Citrulline 178

Individual Drug Interactions

The ingredients in Pump Mango Sorbet interact with 397 drugs. Click any drug to see the details.

2 of the 5 ingredients in Pump Mango Sorbet interact with drugs. Each result below shows which ingredient is responsible. Huperzia serrata L-Citrulline

Each ingredient & the kinds of drugs it affects

For each ingredient in Pump Mango Sorbet with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Huperzia serrata2 drug types · 219 drugs

Anticholinergic Drugs

In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine. Theoretically, concurrent use of anticholinergic drugs and toothed clubmoss might decrease the effectiveness of toothed clubmoss or the anticholinergic drug.
Some anticholinergic drugs include atropine, benztropine (Cogentin), biperiden (Akineton), procyclidine (Kemadrin), and trihexyphenidyl (Artane).

Likelihood Possible Evidence D
Cholinergic Drugs

Huperzine A, a constituent of toothed clubmoss, has demonstrated acetylcholinesterase inhibitory properties. Theoretically, concurrent use of toothed clubmoss with cholinergic drugs might have additive effects and increase the risk of cholinergic side effects.
Cholinergic drugs include bethanechol (Urecholine), donepezil (Aricept), echothiophate (Phospholine Iodide), edrophonium (Enlon, Reversol, Tensilon), neostigmine (Prostigmin), physostigmine (Antilirium), pyridostigmine (Mestinon, Regonol), succinylcholine (Anectine, Quelicin), and tacrine (Cognex).

Likelihood Possible Evidence D
Huperzia serrata full monograph & interactions

L-Citrulline2 drug types · 178 drugs

Antihypertensive Drugs

Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.

Likelihood Possible Evidence B
Phosphodiesterase-5 Inhibitors

Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
L-Citrulline full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pump Mango Sorbet, from the product label.

Alani Nu

See all Alani Nu products
Name
Alani Nutrition LLC
Street Address
7201 Intermodal Dr. Ste A.
City
Louisville
State
KY
ZipCode
40258
Web Address
alaninu.com
Pharmacist Counseling Corner

Pump Mango Sorbet by Alani Nu: Common Questions

Does Pump Mango Sorbet by Alani Nu interact with any medications?
Yes. Based on its ingredients, Pump Mango Sorbet has a known interaction with 397 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pump Mango Sorbet contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take if I'm pregnant or breastfeeding?
There isn't enough safety data for L-citrulline, glycerol, or Huperzia serrata during pregnancy or breastfeeding. The safety data advises against taking these ingredients in supplement form if you're pregnant or nursing. Talk to your doctor or pharmacist for personalized advice.
What's L-citrulline, and why is it in a pre-workout?
L-citrulline is an amino acid your body converts to another compound that widens blood vessels and boosts nitric oxide — that increases blood flow to your muscles, which is what gives you a better pump during exercise. Research suggests it's possibly effective for athletic performance.
What side effects should I expect?
The most common side effects are gastrointestinal — heartburn, bloating, nausea, and diarrhea. Some people also report dizziness and headache. Huperzia serrata may cause dizziness, nausea, and sweating. Most people tolerate it well, but if your stomach is sensitive, start small.
What's glycerol doing in here?
Glycerol (GlycerPump) pulls fluid into your muscles to enhance hydration and is rated possibly effective for athletic performance. It's generally well tolerated, but large doses can cause bloating, nausea, and dehydration concerns.
Can I take this every day?
L-citrulline is generally well tolerated in healthy adults, but long-term safety hasn't been fully studied. Use it as directed on the label, and if you have any chronic health concerns, talk to your pharmacist or doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pump Mango Sorbet label
Go deeper

The Full Monographs Behind Pump Mango Sorbet’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

L-citrulline

Interacts with 178 drugs

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. It is popular for exercise performance an...

Read the full L-citrulline monograph → Herb & supplement monograph

Glycerol

Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well established as a laxative and a skin and eye moi...

Read the full Glycerol monograph → Herb & supplement monograph

Toothed Clubmoss

Interacts with 219 drugs

Toothed Clubmoss is a moss-like plant best known as the natural source of huperzine A, a compound studied mainly for memory and Alzheimer's disease. Some early research is promising, but the...

Read the full Toothed Clubmoss monograph →
Sources

Sources & How We Checked

Pump Mango Sorbet's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

L-citrulline 8 references
  1. Cheng JW, Balwin SN. L-arginine in the management of cardiovascular diseases. Ann Pharmacother 2001;35:755-64. PubMed
  2. Schwedhelm E, Maas R, Freese R, et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol 2008;65:51-9. PubMed
  3. Romero MJ, Platt DH, Caldwell RB, Caldwell RW. Therapeutic use of citrulline in cardiovascular disease. Cardiovasc Drug Rev 2006;24:275-90. PubMed
  4. Balderas-Munoz K, Castillo-Martínez L, Orea-Tejeda A, et al. Improvement of ventricular function in systolic heart failure patients with oral L-citrulline supplementation. Cardiol J 2012;19:612-7. PubMed
  5. Sharif Kashani B, Tahmaseb Pour P, Malekmohammad M, et al. Oral l-citrulline malate in patients with idiopathic pulmonary arterial hypertension and Eisenmenger Syndrome: a clinical trial. J Cardiol 2014;64:231-5. PubMed
  6. Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res 2010;24:1215-22. PubMed
  7. Mirenayat MS, Moradi S, Mohammadi H, Rouhani MH. Effect of L-citrulline supplementation on blood pressure: a systematic review and meta-analysis of clinical trials. Curr Hypertens Rep. 2018;20(11):98. PubMed
  8. Xu Z, Liu C, Liu S, Zhou Z. Comparison of efficacy and safety of daily oral L-arginine and PDE5Is alone or combination in treating erectile dysfunction: A systematic review and meta-analysis of randomised controlled trials. Andrologia. 2021:e14007. PubMed

See these in context on the L-citrulline monograph →

Glycerol 8 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Wagner DR. Hyperhydrating with glycerol: implications for athletic performance. J Am Diet Assoc 1999;99:207-12. PubMed
  3. Yu YL, Kumana CR, Lauder IJ, et al. Treatment of acute cortical infarct with intravenous glycerol. A double-blind, placebo-controlled randomized trial. Stroke 1993;24:1119-24. PubMed
  4. Frei A, Cottier C, Wunderlich P, Ludin E. Glycerol and dextran combined in the therapy of acute stroke. A placebo-controlled, double-blind trial with a planned interim analysis. Stroke 1987;18:373-9. PubMed
  5. Balaskas E, Szepietowski JC, Bessis D, Ioannides D, Ponticelli C, Ghienne C, Taberly A, Dupuy P. Randomized, double-blind study with glycerol and paraffin in uremic xerosis. Clin J Am Soc Nephrol. 2011 Apr;6(4):748-52. PubMed
  6. Blanchet-Bardon C, Tadini G, Machado Matos M, Delarue A. Association of glycerol and paraffin in the treatment of ichthyosis in children: an international, multicentric, randomized, controlled, double-blind study. J Eur Acad Dermatol Venereol. 2012 Aug;26 PubMed
  7. Kajita N, Kanamori K, Yamamoto S, Yoshida K. Generalized Urticaria Caused by a Glycerin Enema in an Infant. J Investig Allergol Clin Immunol 2022;32(4):318-319. PubMed
  8. Suzuki R, Fukuyama K, Miyazaki Y, Namiki T. Contact urticaria syndrome and protein contact dermatitis caused by glycerin enema. JAAD Case Reports. 2016;2:108-10. PubMed

See these in context on the Glycerol monograph →

Toothed Clubmoss 3 references
  1. Budavari S, ed. The Merck Index. 12th ed. Whitehouse Station, NJ: Merck & Co., Inc., 1996.
  2. Zhang RW, Tang XC, Han YY, et al. [Drug evaluation of huperzine A in the treatment of senile memory disorders]. Chung Kuo Yao Li Hsueh Pao 1991;12:250-2.
  3. Ohba T, Yoshino Y, Ishisaka M, et al. Japanese Huperzia serrata extract and the constituent, huperzine A, ameliorate the scopolamine-induced cognitive impairment in mice. Biosci Biotechnol Biochem. 2015;79(11):1838-44.

See these in context on the Toothed Clubmoss monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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