S-Adenosyl-Methionine SAM-e 400 mg By GNC Overview & Drug Interactions
Check For Interactions With S-Adenosyl-Methionine SAM-e 400 mg
Supplement: S-Adenosyl-Methionine SAM-e 400 mg by GNC
S-Adenosyl-Methionine SAM-e 400 mg Label Images
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
SAM-e
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same| Ingredient Group | SAMe |
|---|---|
| Category | non-nutrient/non-botanical |
- Disulfate Monotosylate
Drugs that interact with S-Adenosyl-Methionine SAM-e 400 mg by GNC
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
| Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
|---|---|
| Minimum serving Sizes: |
1 Tablet(s)
|
| Maximum serving Sizes: |
1 Tablet(s)
|
| UPC/BARCODE | 048107124403 |
| Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
|---|---|---|---|
| SAM-e |
400 mg
|
SAMe |
--
|
| Other Ingredients: |
Microcrystalline Cellulose
Mannitol
Glycerol Monostearate
Magnesium Stearate
Silica
Sodium Starch Glycolate
Coating
Forms
|
|---|
Label Statments:
| General |
- CODE 130622 JPG
|
|---|---|
| General Statements |
- A report published by the US Department of Health and Human Services suggests that SAM-e provides clinically significant health benefits for individuals seeking mood support (1600 mg daily), joint comfort and healthy liver function (1200 mg daily). SAM-e provides mood support, as well as relief to joint discomfort, and these benefits are comparable to conventional therapies.
- Conforms to USP <2091> for weight.
- Actual size
- Promotes positive mood balance
Clinically proven benefits for joint support
Supports healthy liver function
|
| Suggested/Recommended/Usage/Directions |
- Directions For Adult Use Only: As a dietary supplement, take one tablet in the morning and one tablet in the afternoon for the first week. If after the first week the desired benefits are not achieved, then you may require a higher level of supplementation. Gradually increase the number of tablets up to eight tablets in divided doses of two tablets (800 mg) throughout the day until benefits are achieved. Do not exceed four tablets daily.
|
| Precautions |
- Do not exceed four tablets daily.
- Warning: Do not use if pregnant or nursing.
- Do not exceed recommended dose.
- If you are taking any medication or are under the care of a physician for depression or related disorder, contact your physician before using this product.
- May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use.
- Caution: Do not use if tamper-evident foil seal over tablets is broken.
- Keep out of reach of children.
|
| Storage |
- Store in a cool, dry place.
|
| FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
|
| FDA Statement of Identity |
- Dietary Supplement
|
Brand Information
See all products by this brand
| Distributed by: | |
|---|---|
| Name | General Nutrition Corporation |
| City | Pittsburgh |
| State | PA |
| ZipCode | 15222 |
| Phone Number | 1-888-462-2548 |
| Web Address | www.gnc.com |
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.