Wild Himalayan Rhodiola Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Wild Himalayan Rhodiola against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Wild Himalayan Rhodiola is a dietary supplement by My Cup of Tee with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, stress and coping (adaptogen), mental performance and focus.Based on those ingredients, 1,271 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Himalayan Rhodiola, Dried, Wild. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Wild Himalayan Rhodiola by My Cup of Tee
Ask about any prescription or over-the-counter medication and we check it for interactions with Wild Himalayan Rhodiola by My Cup of Tee — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Wild Himalayan Rhodiola by My Cup of Tee
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Himalayan Rhodiola, dried wild. It's a traditional adaptogenic herb — a plant that's believed to help your body manage stress — though the strength of evidence for various claimed uses varies.
There are no other inactive ingredients listed.
Does it work?
Not established
The evidence file we hold doesn't establish effectiveness for rhodiola on any of the uses tracked in our data. The condition ratings we have for it — altitude sickness, anxiety, heart rhythm, athletic performance, and bladder cancer — all show insufficient reliable evidence.
That doesn't mean it doesn't work; it means rigorous clinical evidence isn't available yet in our system. If you're considering this for a specific reason, your pharmacist can point you toward what the broader research landscape shows.
How safe is it?
Well-documented data
Rhodiola is generally well tolerated for short-term use, though long-term safety hasn't been well studied. The most common side effects are dizziness and changes in saliva production — either dry mouth or excess salivation — and these are typically mild.
The safety data advises against use during pregnancy and while breastfeeding because there isn't enough information to know it's safe in those situations. Talk with your pharmacist or doctor if you're pregnant, planning to become pregnant, or nursing.
Meds to double-check
Moderate interaction found
Before you start, double-check with your pharmacist if you take blood pressure medications (antihypertensives) — rhodiola could lower your pressure further. Also flag diabetes medications, immunosuppressants, or any drug metabolized by your liver's CYP2C9 and P-glycoprotein pathways, including losartan (Cozaar).
Use the medication checker on this page to run your exact drugs.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Wild Himalayan Rhodiola might appeal to you if you're looking for a traditional stress-support herb and don't take blood pressure, diabetes, or immune-suppressing medications. But if you're on any prescription drugs — especially for blood pressure, diabetes, or immune system control — check with your pharmacist first.
The interactions are real and worth confirming aren't a problem for your specific situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Wild Himalayan Rhodiola, straight from the product label.
| Brand | My Cup of Tee |
|---|---|
| Barcode (UPC) | 679372081223 |
| Net contents | 3.5 Ounce(s); 99 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Dec 13, 2022 |
| DSLD ID | 279083 |
| Product type | Botanical |
| Supplement form | Other (e.g. Tea Bag) |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Wild Himalayan Rhodiola by My Cup of Tee, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Himalayan Rhodiola, Dried, Wild | 1 Gram(s) | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Dietary Supplement
Formula
Himalayan Rhodiola, from above the snowline of Bhutan and Tibet, is one of the most precious tonic herbs in the world. It cannot be cultivated, and is only collected from the wild, so it is only available in very limited quantities.
Suggested/Recommended/Usage/Directions
Use a tiny amount in your DBG daily for enhanced oxygenation and adaptability.
Directions: Add the amount of botanicals per a recipe, as desired, or as directed by a health practitioner. The proper way of extracting botanicals depends on parts used. Flowers, fruits and leaves can usually be steeped or decocted (boiling over fire) while stems, barks and roots typically require decocting. In a Desktop Botanical Garden Glass Tea & Elixir maker, add 1 part botanical(s) and 5-8 parts water, steep or decoct for 5-20 minutes. You can boil water directly in the elixir maker. Repeat this process for 2nd or 3rd extraction until all active constituents have been extracted.
Formulation
Flavor - Bright floral top notes with heavier sweet and lightly bitter undertones and a dry finish.
Precautions
Manufactured in a facility that processes tree nuts.
General Statements
Scan the QR code for more my My Cup of Tee ideas and recipes
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Wild Himalayan Rhodiola by My Cup of Tee label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Wild Himalayan Rhodiola by My Cup of Tee
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Gram(s) Dosage formOther (e.g. Tea Bag) Servings per container99 Amounts shown are per serving.
Himalayan Rhodiola, Dried, Wild
Interacts with1,271 drugs
Rhodiola is an herb traditionally used to fight fatigue and help the body cope with stress. Some small studies suggest it may modestly reduce fatigue...
Himalayan Rhodiola, Dried, Wild monograph & interactionsWild Himalayan Rhodiola by My Cup of Tee Drug Interactions
HelloPharmacist Interaction Report
Wild Himalayan Rhodiola by My Cup of Tee contains one active ingredient — Himalayan Rhodiola — that does interact with medications.
The most serious concerns are with blood pressure medications (antihypertensives). Rhodiola may lower blood pressure on its own, and combining it with drugs that do the same could push your pressure too low.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to flag this with your pharmacist if you take diabetes medications. Rhodiola might lower blood glucose further, raising the risk of low blood sugar (hypoglycemia).
There are also moderate interactions documented with immunosuppressants — drugs that calm down your immune system — because rhodiola appears to stimulate immune activity, which could work against those medications.
Rhodiola also affects how your liver processes several types of drugs. It inhibits enzymes called CYP2C9 and P-glycoprotein, which means it can raise levels of medications broken down by those pathways — including the blood pressure drug losartan (Cozaar), where a clinical study showed a 21% reduction in how fast the body clears it.
Minor interactions are also documented with drugs metabolized by CYP1A2 and CYP3A4, though a clinical trial in healthy males found those effects were not significant at a 290 mg daily dose. Altogether, these interactions span 1,253 individual medications.
Use the medication checker below to look up your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Wild Himalayan Rhodiola?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Wild Himalayan Rhodiola interact with 1,271 drugs. Click any drug to see the details.
1 of the 1 ingredient in Wild Himalayan Rhodiola interact with drugs. Each result below shows which ingredient is responsible. Himalayan Rhodiola, Dried, Wild
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildImmunosuppressants Moderate
Interaction Summary
Theoretically, rhodiola use might interfere with immunosuppressive therapy.
Read the full Himalayan Rhodiola, Dried, Wild + 6-mercaptopurine interactionAbrocitinibCibinqo
How Abrocitinib interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildCytochrome P450 2c9 (cyp2c9) Substrates, Immunosuppressants Moderate
Interaction Summary
Theoretically, rhodiola might increase levels of drugs metabolized by CYP2C9.
Read the full Himalayan Rhodiola, Dried, Wild + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, rhodiola might increase levels of P-glycoprotein substrates.
Read the full Himalayan Rhodiola, Dried, Wild + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rhodiola with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Himalayan Rhodiola, Dried, Wild + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking rhodiola with antihypertensive drugs might increase the risk of hypotension.
Read the full Himalayan Rhodiola, Dried, Wild + Acebutolol interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, rhodiola might increase levels of drugs metabolized by CYP2C9.
Read the full Himalayan Rhodiola, Dried, Wild + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildAntihypertensive Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking rhodiola with antihypertensive drugs might increase the risk of hypotension.
Read the full Himalayan Rhodiola, Dried, Wild + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rhodiola with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Himalayan Rhodiola, Dried, Wild + Acetohexamide interactionAdalimumabHumira
How Adalimumab interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildImmunosuppressants Moderate
Interaction Summary
Theoretically, rhodiola use might interfere with immunosuppressive therapy.
Read the full Himalayan Rhodiola, Dried, Wild + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildImmunosuppressants Moderate
Interaction Summary
Theoretically, rhodiola use might interfere with immunosuppressive therapy.
Read the full Himalayan Rhodiola, Dried, Wild + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildImmunosuppressants Moderate
Interaction Summary
Theoretically, rhodiola use might interfere with immunosuppressive therapy.
Read the full Himalayan Rhodiola, Dried, Wild + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildImmunosuppressants Moderate
Interaction Summary
Theoretically, rhodiola use might interfere with immunosuppressive therapy.
Read the full Himalayan Rhodiola, Dried, Wild + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildImmunosuppressants Moderate
Interaction Summary
Theoretically, rhodiola use might interfere with immunosuppressive therapy.
Read the full Himalayan Rhodiola, Dried, Wild + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildImmunosuppressants Moderate
Interaction Summary
Theoretically, rhodiola use might interfere with immunosuppressive therapy.
Read the full Himalayan Rhodiola, Dried, Wild + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildImmunosuppressants Moderate
Interaction Summary
Theoretically, rhodiola use might interfere with immunosuppressive therapy.
Read the full Himalayan Rhodiola, Dried, Wild + Adalimumab-fkjp interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, rhodiola might increase levels of drugs metabolized by CYP2C9.
Read the full Himalayan Rhodiola, Dried, Wild + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAfatinib DimaleateGilotrif
How Afatinib Dimaleate interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, rhodiola might increase levels of P-glycoprotein substrates.
Read the full Himalayan Rhodiola, Dried, Wild + Afatinib Dimaleate interactionAgomelatineValdoxan
How Agomelatine interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates +1 Moderate
Interaction Summary
Theoretically, rhodiola might increase levels of drugs metabolized by CYP1A2.
Read the full Himalayan Rhodiola, Dried, Wild + Agomelatine interactionAlbiglutideTanzeum
How Albiglutide interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rhodiola with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Himalayan Rhodiola, Dried, Wild + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildImmunosuppressants Moderate
Interaction Summary
Theoretically, rhodiola use might interfere with immunosuppressive therapy.
Read the full Himalayan Rhodiola, Dried, Wild + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildImmunosuppressants Moderate
Interaction Summary
Theoretically, rhodiola use might interfere with immunosuppressive therapy.
Read the full Himalayan Rhodiola, Dried, Wild + Alemtuzumab interactionAliskirenTekturna
How Aliskiren interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, rhodiola might increase levels of drugs metabolized by CYP3A4.
Read the full Himalayan Rhodiola, Dried, Wild + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildAntidiabetes Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rhodiola with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Himalayan Rhodiola, Dried, Wild + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rhodiola with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Himalayan Rhodiola, Dried, Wild + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildAntidiabetes Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rhodiola with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Himalayan Rhodiola, Dried, Wild + Alogliptin, Pioglitazone interactionAlvimopanEntereg
How Alvimopan interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, rhodiola might increase levels of P-glycoprotein substrates.
Read the full Himalayan Rhodiola, Dried, Wild + Alvimopan interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildP-glycoprotein Substrates, Antihypertensive Drugs +1 Moderate
Interaction Summary
Theoretically, rhodiola might increase levels of P-glycoprotein substrates.
Read the full Himalayan Rhodiola, Dried, Wild + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking rhodiola with antihypertensive drugs might increase the risk of hypotension.
Read the full Himalayan Rhodiola, Dried, Wild + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking rhodiola with antihypertensive drugs might increase the risk of hypotension.
Read the full Himalayan Rhodiola, Dried, Wild + Amiloride, Hydrochlorothiazide interactionAmitriptylineElavil
How Amitriptyline interacts with Wild Himalayan Rhodiola — through 1 ingredient. Tap an ingredient for the detail:
Himalayan Rhodiola, Dried, WildCytochrome P450 3a4 (cyp3a4) Substrates, Antidepressant Drugs +3 Moderate
Interaction Summary
Theoretically, rhodiola might increase levels of drugs metabolized by CYP3A4.
Read the full Himalayan Rhodiola, Dried, Wild + Amitriptyline interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Wild Himalayan Rhodiola with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Himalayan Rhodiola, Dried, Wild
Antidiabetes Drugs
Theoretically, taking rhodiola with antidiabetes drugs might increase the risk of hypoglycemia.
In vitro and animal research shows that rhodiola extract can decrease blood glucose due to alpha-glucosidase activity.
Antihypertensive Drugs
Theoretically, taking rhodiola with antihypertensive drugs might increase the risk of hypotension.
In vitro and animal research shows that rhodiola extract inhibits angiotensin-converting enzyme (ACE) and might lower blood pressure.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, rhodiola might increase levels of drugs metabolized by CYP2C9.
In vitro research shows that rhodiola inhibits CYP2C9. This effect is highly variable and appears to be dependent on the rhodiola product studied. Also, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days reduces the metabolism of losartan, a CYP2C9 substrate, by 21% after 4 hours.
Immunosuppressants
Theoretically, rhodiola use might interfere with immunosuppressive therapy.
In vitro and animal research show that rhodiola has immunostimulatory effects.
Losartan (Cozaar)
Rhodiola might increase the levels and adverse effects of losartan.
A clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days reduces the metabolism of losartan, a CYP2C9 substrate, by 21% after 4 hours.
P-Glycoprotein Substrates
Theoretically, rhodiola might increase levels of P-glycoprotein substrates.
In vitro research shows that rhodiola inhibits P-glycoprotein. Theoretically, using rhodiola with P-glycoprotein substrates might increase drug levels and potentially increase the risk of adverse effects.
Antidepressant Drugs
Theoretically, rhodiola might increase the risk of adverse effects when taken with antidepressants.
A review of adverse event reports in Poland identified cases of tachyarrhythmias, myalgia, arthralgia, gum pain, restless leg syndrome, swallowing disorders, and changes in consciousness when rhodiola was taken in combination with paroxetine, escitalopram, fluoxetine, sertraline, trazodone, and/or duloxetine.
Cns Depressants
Theoretically, rhodiola might increase the risk of adverse effects when taken with CNS depressants.
A review of adverse event reports in Poland identified cases of excessive sedation, myoclonus, hypotension, and hallucinations when rhodiola was taken with haloperidol, diazepam, or alprazolam.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, rhodiola might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that rhodiola inhibits CYP1A2. This effect is highly variable and appears to be dependent on the rhodiola product studied. However, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days does not inhibit the metabolism of caffeine, a CYP1A2 substrate.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, rhodiola might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that rhodiola inhibits CYP3A4. This effect is highly variable and appears to be dependent on the rhodiola product studied. However, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days does not inhibit the metabolism of midazolam, a CYP3A4 substrate.
Brand information
Manufacturer and brand details for Wild Himalayan Rhodiola, from the product label.
My Cup of Tee
See all My Cup of Tee products- Name
- Ron Teeguarden's Dragon Herbs
- Street Address
- P.O. Box 361459
- City
- Los Angeles
- State
- CA
- ZipCode
- 90036
- Phone Number
- (888) 558-6642
- Web Address
- www.dragonherbs.com
Wild Himalayan Rhodiola by My Cup of Tee: Common Questions
Does Wild Himalayan Rhodiola by My Cup of Tee interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe to take during pregnancy?
Can I take this while breastfeeding?
What side effects does rhodiola cause?
Does this actually work for stress or anxiety?
Why does this interact with so many medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Wild Himalayan Rhodiola is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Wild Himalayan Rhodiola’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Wild Himalayan Rhodiola's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 13 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Rhodiola 13 references
- Kim SH, Hyun SH, Choung SY. Antioxidative effects of Cinnamomi cassiae and Rhodiola rosea extracts in liver of diabetic mice. Biofactors 2006;26:209-19.
- Kwon YI, Jang HD, Shetty K. Evaluation of Rhodiola crenulata and Rhodiola rosea for management of type II diabetes and hypertension. Asia Pac J Clin Nutr 2006;15:425-32.
- Bystritsky A, Kerwin L, Feusner JD. A pilot study of Rhodiola rosea (Rhodax) for generalized anxiety disorder (GAD). J Altern Complement Med 2008;14:175-80.
- Shevtsov VA, Zholus BI, Shervarly VI, et al. A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine 2003;10:95-105. PubMed
- Apostolidis E, Kwon YI, Shetty K. Potential of cranberry-based herbal synergies for diabetes and hypertension management. Asia Pac J Clin Nutr 2006;15:433-41.
- Hellum BH, Tosse A, Hoybakk K, et al. Potent in vitro inhibition of CYP3A4 and P-glycoprotein by Rhodiola rosea. Planta Med 2010;76:331-8.
- Skopriska-Rozewska E, Wojcik R, Siwicki AK, et al. The effect of Rhodiola quadrifida extracts on cellular immunity in mice and rats. Pol J Vet Sci 2008;11:105-11.
- Mishra KP, Chanda S, Shukla K, Ganju L. Adjuvant effect of aqueous extract of Rhodiola imbricate rhizome on the immune responses to tetanus toxoid and ovalbumin in rats. Immunopharmacol Immunotoxicol 2010;32:141-6.
- Li HX, Sze SC, Tong Y, Ng TB. Production of Th1- and Th2-dependent cytokines induced by the Chinese medicine herb, Rhodiola algida, on human peripheral blood monocytes. J Ethnopharmacol 2009;123:257-66. PubMed
- Mishra KP, Ganju L, Chanda S, et al. Aqueous extract of Rhodiola imbricate rhizome stimulates Toll-like receptor 4, granzyme-B and Th1 cytokines in vitro. Immunobiology 2009;214:27-31.
- Thu OK, Nilsen OG, Hellum B. In vitro inhibition of cytochrome P-450 activities and quantification of constituents in a selection of commercial Rhodiola rosea products. Pharm Bio. 2016 Dec;54(12):3249-3256.
- Thu OK, Spigset O, Nilsen OG, Hellum B. Effect of commercial Rhodiola rosea on CYP enzyme activity in humans. Eur J Clin Pharmacol. 2016 Mar;72(3):295-300. PubMed
- Woron J, Siwek M. Unwanted effects of psychotropic drug interactions with medicinal products and diet supplements containing plant extracts. Psychiatr Pol 2018;52(6):983-96. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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