Alogliptin

Generic name: Pronounced as (al'' oh glip' tin)
Brand names
  • Nesina®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 06/15/2016

Alogliptin is used along with diet and exercise to lower blood sugar levels in patients with type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin normally). Alogliptin is in a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the amount of insulin in the body to control blood sugar. Alogliptin is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may develop if high blood sugar is not treated).

Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

Alogliptin comes as a tablet to take by mouth. It is usually taken with or without food once a day. Take alogliptin at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take alogliptin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Alogliptin controls diabetes but does not cure it. Continue to take alogliptin even if you feel well. Do not stop taking alogliptin without talking to your doctor.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with alogliptin and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking alogliptin,

  • tell your doctor and pharmacist if you are allergic to alogliptin; other DPP-4 inhibitors including linagliptin (Tradjenta, in Glyxambi, in Jentadueto), saxagliptin (Onglyza, in Kombiglyze), sitagliptin (Januvia, in Janumet); any other medications, or any of the ingredients in alogliptin tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention insulin and other medications for diabetes. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you drink or have ever drunk large amounts of alcohol and if you have or have ever had pancreatitis (swelling of the pancreas), gallstones, heart failure, or kidney or liver disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking alogliptin, call your doctor.

  • if you are having surgery including dental surgery, tell the doctor or dentist that you are taking alogliptin.

  • talk to your doctor about what you should do if you get hurt or if you develop a fever or infection. These conditions may affect your blood sugar and the amount of alogliptin you may need.

Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. It is important to eat a healthy diet, exercise regularly, and lose weight if necessary. This will help to control your diabetes and help alogliptin work more effectively.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

This medication may cause changes in your blood sugar. You should know the symptoms of high and low blood sugar and what to do if you develop these symptoms.

  • Alogliptin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • headache

    • stuffy or runny nose

    • sore throat

    • joint pain

  • Some side effects can be serious. If you experience any of these symptoms, stop taking alogliptin and call your doctor immediately or get emergency medical treatment:

    • severe stomach pain that may move to your back

    • vomiting

    • excessive tiredness

    • loss of appetite

    • pain in the right upper area of the stomach

    • dark urine

    • yellowing of the skin or eyes

    • fever

    • blisters

    • skin peeling

    • rash

    • hives

    • itching

    • swelling of the eyes, face, lips, tongue, or throat

    • hoarseness

    • difficulty breathing or swallowing

    • shortness of breath, especially when lying down

    • swelling of the feet, ankles, or legs

    • sudden weight gain

  • Alogliptin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor will probably order certain laboratory tests to check your body's response to alogliptin. Your blood sugar and glycosylated hemoglobin (HbA1c) should be checked regularly to determine your response to alogliptin. Your doctor may also tell you how to check your response to alogliptin by measuring your blood or urine sugar levels at home. Follow these directions carefully.

You should always wear a diabetic identification bracelet to be sure you get proper treatment in an emergency.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • Kazano® (containing Alogliptin, Metformin)
  • Oseni® (containing Alogliptin, Pioglitazone)

Drug Interaction
Moxifloxacin Moxifloxacin The therapeutic efficacy of Alogliptin can be increased when used in combination with Moxifloxacin.
Repaglinide Repaglinide The risk or severity of hypoglycemia can be increased when Repaglinide is combined with Alogliptin.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection Alogliptin may increase the hypoglycemic activities of Insulin glargine.
Delavirdine Delavirdine The metabolism of Alogliptin can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Alogliptin can be decreased when combined with Nevirapine.
Dolasetron Dolasetron The metabolism of Alogliptin can be decreased when combined with Dolasetron.
Cilostazol Cilostazol Cilostazol may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The risk or severity of angioedema can be increased when Conjugated estrogens is combined with Alogliptin.
Fenofibrate Fenofibrate Fenofibrate may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Guanfacine Guanfacine Guanfacine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Magnesium Hydroxide Magnesium Hydroxide Alogliptin may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Miglitol Miglitol The risk or severity of hypoglycemia can be increased when Miglitol is combined with Alogliptin.
Mycophenolate Mycophenolate Mycophenolic acid may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Olsalazine Olsalazine Olsalazine may increase the hypoglycemic activities of Alogliptin.
Penbutolol Penbutolol The therapeutic efficacy of Alogliptin can be increased when used in combination with Acebutolol.
Potassium Potassium Potassium cation may increase the excretion rate of Alogliptin which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone Prednisone The risk or severity of hyperglycemia can be increased when Prednisone is combined with Alogliptin.
Ranitidine Ranitidine The metabolism of Alogliptin can be decreased when combined with Ranitidine.
Reserpine Reserpine Reserpine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Rizatriptan Rizatriptan Rizatriptan may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Sumatriptan Sumatriptan The therapeutic efficacy of Alogliptin can be increased when used in combination with Sumatriptan.
Tacrolimus Tacrolimus Tacrolimus may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Triamcinolone Triamcinolone The risk or severity of hyperglycemia can be increased when Triamcinolone is combined with Alogliptin.
Ampicillin Injection Ampicillin Injection Ampicillin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection Doxycycline may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Fluconazole Injection Fluconazole Injection The risk or severity of hypoglycemia can be increased when Alogliptin is combined with Fluconazole.
Foscarnet Injection Foscarnet Injection Foscarnet may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Hydromorphone Injection Hydromorphone Injection Hydromorphone may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Levofloxacin Injection Levofloxacin Injection The therapeutic efficacy of Alogliptin can be increased when used in combination with Levofloxacin.
Meperidine Injection Meperidine Injection Meperidine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Methylprednisolone Injection Methylprednisolone Injection The risk or severity of hyperglycemia can be increased when Methylprednisolone is combined with Alogliptin.
Metoclopramide Injection Metoclopramide Injection The metabolism of Alogliptin can be decreased when combined with Metoclopramide.
Pamidronate Injection Pamidronate Injection Pamidronic acid may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Vancomycin Injection Vancomycin Injection Alogliptin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Altretamine Altretamine Amphetamine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Alogliptin.
Ondansetron Ondansetron The metabolism of Alogliptin can be decreased when combined with Ondansetron.
Torsemide Torsemide The therapeutic efficacy of Alogliptin can be increased when used in combination with Torasemide.
Olanzapine Olanzapine The therapeutic efficacy of Alogliptin can be decreased when used in combination with Olanzapine.
Entacapone Entacapone The metabolism of Alogliptin can be decreased when combined with Entacapone.
Eprosartan Eprosartan The risk or severity of angioedema can be increased when Eprosartan is combined with Alogliptin.
Hydroxychloroquine Hydroxychloroquine The therapeutic efficacy of Alogliptin can be increased when used in combination with Hydroxychloroquine.
Meloxicam Meloxicam Meloxicam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Telmisartan Telmisartan The risk or severity of angioedema can be increased when Telmisartan is combined with Alogliptin.
Temozolomide Temozolomide Temozolomide may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Zaleplon Zaleplon Zaleplon may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Anakinra Anakinra The metabolism of Alogliptin can be increased when combined with Anakinra.
Linezolid Linezolid Linezolid may increase the hypoglycemic activities of Alogliptin.
Trimipramine Trimipramine The metabolism of Alogliptin can be decreased when combined with Trimipramine.
Etanercept Injection Etanercept Injection The metabolism of Alogliptin can be increased when combined with Etanercept.
Perindopril Perindopril The risk or severity of angioedema can be increased when Perindopril is combined with Alogliptin.
Tenofovir Tenofovir Tenofovir may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Sirolimus Sirolimus The therapeutic efficacy of Alogliptin can be decreased when used in combination with Sirolimus.
Epinephrine Injection Epinephrine Injection The therapeutic efficacy of Alogliptin can be decreased when used in combination with Epinephrine.
Eplerenone Eplerenone Eplerenone may increase the excretion rate of Alogliptin which could result in a lower serum level and potentially a reduction in efficacy.
Escitalopram Escitalopram The serum concentration of Alogliptin can be increased when it is combined with Escitalopram.
Zonisamide Zonisamide The therapeutic efficacy of Alogliptin can be increased when used in combination with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Alogliptin can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The therapeutic efficacy of Alogliptin can be decreased when used in combination with Aripiprazole.
Atomoxetine Atomoxetine Atomoxetine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Atazanavir Atazanavir Atazanavir may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Almotriptan Almotriptan Almotriptan may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Eletriptan Eletriptan The metabolism of Alogliptin can be decreased when combined with Eletriptan.
Mefloquine Mefloquine The metabolism of Alogliptin can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin The therapeutic efficacy of Alogliptin can be increased when used in combination with Rosuvastatin.
Emtricitabine Emtricitabine Emtricitabine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Memantine Memantine Memantine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Tegaserod Tegaserod The metabolism of Alogliptin can be decreased when combined with Tegaserod.
Tadalafil Tadalafil Tadalafil may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Fosamprenavir Fosamprenavir The therapeutic efficacy of Alogliptin can be decreased when used in combination with Fosamprenavir.
Gemifloxacin Gemifloxacin The therapeutic efficacy of Alogliptin can be increased when used in combination with Gemifloxacin.
Progesterone Progesterone The therapeutic efficacy of Alogliptin can be decreased when used in combination with Progesterone.
Infliximab Injection Infliximab Injection The metabolism of Alogliptin can be increased when combined with Infliximab.
Oxandrolone Oxandrolone Oxandrolone may increase the hypoglycemic activities of Alogliptin.
Protriptyline Protriptyline Protriptyline may decrease the hypoglycemic activities of Alogliptin.
Duloxetine Duloxetine The metabolism of Alogliptin can be decreased when combined with Duloxetine.
Norethindrone Norethindrone The therapeutic efficacy of Alogliptin can be decreased when used in combination with Norethisterone.
Tinidazole Tinidazole Tinidazole may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Trospium Trospium The metabolism of Alogliptin can be decreased when combined with Trospium.
Bosentan Bosentan The therapeutic efficacy of Alogliptin can be increased when used in combination with Bosentan.
Cefditoren Cefditoren Cefdinir may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cinacalcet Cinacalcet The metabolism of Alogliptin can be decreased when combined with Cinacalcet.
Cyanocobalamin Injection Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Erlotinib Erlotinib The metabolism of Alogliptin can be decreased when combined with Erlotinib.
Eszopiclone Eszopiclone Eszopiclone may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Ganciclovir Ganciclovir Ganciclovir may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Insulin Aspart (rDNA Origin) Injection Insulin Aspart (rDNA Origin) Injection Alogliptin may increase the hypoglycemic activities of Insulin aspart.
Ribavirin Ribavirin Ribavirin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Solifenacin Solifenacin The metabolism of Alogliptin can be decreased when combined with Solifenacin.
Valganciclovir Valganciclovir Valganciclovir may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Adefovir Adefovir Adefovir may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine Amphetamine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Alogliptin can be decreased when combined with Peginterferon alfa-2b.
Pramlintide Injection Pramlintide Injection The risk or severity of hypoglycemia can be increased when Pramlintide is combined with Alogliptin.
Exenatide Injection Exenatide Injection The risk or severity of hypoglycemia can be increased when Exenatide is combined with Alogliptin.
Isocarboxazid Isocarboxazid Isocarboxazid may increase the hypoglycemic activities of Alogliptin.
Ramelteon Ramelteon Ramelteon may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Alogliptin.
Fentanyl Fentanyl Fentanyl may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Pregabalin Pregabalin The risk or severity of angioedema can be increased when Pregabalin is combined with Alogliptin.
Tipranavir Tipranavir The metabolism of Tipranavir can be decreased when combined with Alogliptin.
Insulin Detemir (rDNA Origin) Injection Insulin Detemir (rDNA Origin) Injection Alogliptin may increase the hypoglycemic activities of Insulin detemir.
Ranolazine Ranolazine The serum concentration of Alogliptin can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Alogliptin can be increased when combined with Abatacept.
Rasagiline Rasagiline Rasagiline may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Imatinib Imatinib The metabolism of Alogliptin can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin The risk or severity of angioedema can be increased when Sitagliptin is combined with Alogliptin.
Varenicline Varenicline Varenicline may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Gefitinib Gefitinib The metabolism of Alogliptin can be decreased when combined with Gefitinib.
Albuterol Albuterol Salbutamol may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Paliperidone Paliperidone The therapeutic efficacy of Alogliptin can be decreased when used in combination with Paliperidone.
Bortezomib Bortezomib The metabolism of Alogliptin can be decreased when combined with Bortezomib.
Clofarabine Injection Clofarabine Injection Clofarabine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection Alogliptin may increase the hypoglycemic activities of Insulin glulisine.
Lubiprostone Lubiprostone Lubiprostone may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Primaquine Primaquine The metabolism of Alogliptin can be decreased when combined with Primaquine.
Bismuth Subsalicylate Bismuth Subsalicylate Bismuth subsalicylate may increase the hypoglycemic activities of Alogliptin.
Darunavir Darunavir The therapeutic efficacy of Alogliptin can be decreased when used in combination with Darunavir.
Pemetrexed Injection Pemetrexed Injection Alogliptin may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Lisdexamfetamine Lisdexamfetamine The metabolism of Alogliptin can be decreased when combined with Lisdexamfetamine.
Vorinostat Vorinostat The therapeutic efficacy of Alogliptin can be decreased when used in combination with Vorinostat.
Sorafenib Sorafenib The metabolism of Alogliptin can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Alogliptin.
Levocetirizine Levocetirizine Alogliptin may decrease the excretion rate of Levocetirizine which could result in a higher serum level.
Pegaptanib Injection Pegaptanib Injection Pegaptanib may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Mexiletine Mexiletine The metabolism of Alogliptin can be decreased when combined with Mexiletine.
Azacitidine Injection Azacitidine Injection Azacitidine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Temsirolimus Temsirolimus The therapeutic efficacy of Alogliptin can be decreased when used in combination with Temsirolimus.
Lenalidomide Lenalidomide Lenalidomide may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Nilotinib Nilotinib The metabolism of Alogliptin can be decreased when combined with Nilotinib.
Budesonide Budesonide The risk or severity of hyperglycemia can be increased when Budesonide is combined with Alogliptin.
Desmopressin Desmopressin Desmopressin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Doripenem Injection Doripenem Injection Alogliptin may decrease the excretion rate of Doripenem which could result in a higher serum level.
Arsenic Trioxide Injection Arsenic Trioxide Injection The therapeutic efficacy of Alogliptin can be decreased when used in combination with Arsenic trioxide.
Desvenlafaxine Desvenlafaxine The risk or severity of hypoglycemia can be increased when Alogliptin is combined with Desvenlafaxine.
Cevimeline Cevimeline Cevimeline may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Nebivolol Nebivolol The therapeutic efficacy of Alogliptin can be increased when used in combination with Nebivolol.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Alogliptin.
Certolizumab Injection Certolizumab Injection The metabolism of Certolizumab pegol can be increased when combined with Alogliptin.
Daptomycin Injection Daptomycin Injection Daptomycin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Methylnaltrexone Injection Methylnaltrexone Injection Alogliptin may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Midazolam Midazolam Midazolam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Dexrazoxane Injection Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Milnacipran Milnacipran The risk or severity of hypoglycemia can be increased when Milnacipran is combined with Alogliptin.
Plerixafor Injection Plerixafor Injection Alogliptin may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Fesoterodine Fesoterodine Alogliptin may decrease the excretion rate of Fesoterodine which could result in a higher serum level.
Betaxolol Betaxolol The therapeutic efficacy of Alogliptin can be increased when used in combination with Betaxolol.
Iloperidone Iloperidone The therapeutic efficacy of Alogliptin can be decreased when used in combination with Iloperidone.
Prasugrel Prasugrel Alogliptin may decrease the excretion rate of Prasugrel which could result in a higher serum level.
Everolimus Everolimus The metabolism of Alogliptin can be decreased when combined with Everolimus.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) Tolvaptan may increase the excretion rate of Alogliptin which could result in a lower serum level and potentially a reduction in efficacy.
Dronedarone Dronedarone The metabolism of Dronedarone can be decreased when combined with Alogliptin.
Pralatrexate Injection Pralatrexate Injection Alogliptin may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection Palonosetron may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Saxagliptin Saxagliptin The risk or severity of angioedema can be increased when Alogliptin is combined with Saxagliptin.
Telavancin Injection Telavancin Injection Alogliptin may decrease the excretion rate of Telavancin which could result in a higher serum level.
Tapentadol Tapentadol The metabolism of Alogliptin can be decreased when combined with Tapentadol.
Topotecan Topotecan Topotecan may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Golimumab Injection Golimumab Injection The metabolism of Alogliptin can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Alogliptin can be decreased when combined with Pazopanib.
Asenapine Asenapine The therapeutic efficacy of Alogliptin can be decreased when used in combination with Asenapine.
Levonorgestrel Levonorgestrel The therapeutic efficacy of Alogliptin can be decreased when used in combination with Levonorgestrel.
Oxymorphone Oxymorphone The metabolism of Alogliptin can be decreased when combined with Oxymorphone.
Liraglutide Injection Liraglutide Injection The risk or severity of hypoglycemia can be increased when Alogliptin is combined with Liraglutide.
Tocilizumab Injection Tocilizumab Injection The metabolism of Alogliptin can be increased when combined with Tocilizumab.
Dalfampridine Dalfampridine Alogliptin may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Lurasidone Lurasidone The therapeutic efficacy of Alogliptin can be decreased when used in combination with Lurasidone.
Acetaminophen Injection Acetaminophen Injection Acetaminophen may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Vilazodone Vilazodone The metabolism of Alogliptin can be decreased when combined with Vilazodone.
Ipilimumab Injection Ipilimumab Injection Ipilimumab may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Terbutaline Injection Terbutaline Injection Terbutaline may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Azilsartan Azilsartan The risk or severity of angioedema can be increased when Alogliptin is combined with Azilsartan medoxomil.
Roflumilast Roflumilast Roflumilast may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Linagliptin Linagliptin The risk or severity of angioedema can be increased when Alogliptin is combined with Linagliptin.
Rilpivirine Rilpivirine The metabolism of Alogliptin can be decreased when combined with Rilpivirine.
Abiraterone Abiraterone The metabolism of Alogliptin can be decreased when combined with Abiraterone.
Triptorelin Injection Triptorelin Injection The therapeutic efficacy of Alogliptin can be decreased when used in combination with Triptorelin.
Rivaroxaban Rivaroxaban Alogliptin may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ruxolitinib Ruxolitinib Alogliptin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Clobazam Clobazam The metabolism of Alogliptin can be decreased when combined with Clobazam.
Vemurafenib Vemurafenib The therapeutic efficacy of Alogliptin can be increased when used in combination with Vemurafenib.
Deferiprone Deferiprone Alogliptin may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Naloxone Injection Naloxone Injection Naloxone may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Fondaparinux Injection Fondaparinux Injection Fondaparinux may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Enzalutamide Enzalutamide Alogliptin may decrease the excretion rate of Enzalutamide which could result in a higher serum level.
Mirabegron Mirabegron The metabolism of Mirabegron can be decreased when combined with Alogliptin.
Corticotropin, Repository Injection Corticotropin, Repository Injection The risk or severity of hyperglycemia can be increased when Corticotropin is combined with Alogliptin.
Lorcaserin Lorcaserin The risk or severity of hypoglycemia can be increased when Mecasermin is combined with Alogliptin.
Teduglutide Injection Teduglutide Injection Alogliptin may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Alogliptin.
Pomalidomide Pomalidomide Alogliptin may decrease the excretion rate of Pomalidomide which could result in a higher serum level.
Canagliflozin Canagliflozin Canagliflozin may increase the hypoglycemic activities of Alogliptin.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Alogliptin which could result in a lower serum level and potentially a reduction in efficacy.
Dabrafenib Dabrafenib The therapeutic efficacy of Alogliptin can be decreased when used in combination with Dabrafenib.
Ospemifene Ospemifene The metabolism of Alogliptin can be decreased when combined with Ospemifene.
Trametinib Trametinib Alogliptin may decrease the excretion rate of Trametinib which could result in a higher serum level.
Levomilnacipran Levomilnacipran The risk or severity of hypoglycemia can be increased when Alogliptin is combined with Levomilnacipran.
Ertapenem Injection Ertapenem Injection Ertapenem may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Vortioxetine Vortioxetine Alogliptin may decrease the excretion rate of Vortioxetine which could result in a higher serum level.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Alogliptin.
Ketorolac Injection Ketorolac Injection Ketorolac may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Simeprevir Simeprevir The therapeutic efficacy of Alogliptin can be increased when used in combination with Simeprevir.
Sofosbuvir Sofosbuvir Alogliptin may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin Dapagliflozin may increase the hypoglycemic activities of Alogliptin.
Apremilast Apremilast The metabolism of Alogliptin can be increased when combined with Apremilast.
Droxidopa Droxidopa Alogliptin may decrease the excretion rate of Droxidopa which could result in a higher serum level.
Ceritinib Ceritinib The therapeutic efficacy of Alogliptin can be decreased when used in combination with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Alogliptin can be increased when combined with Siltuximab.
Albiglutide Injection Albiglutide Injection The risk or severity of hypoglycemia can be increased when Alogliptin is combined with Albiglutide.
Testosterone Injection Testosterone Injection Testosterone may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Oritavancin Injection Oritavancin Injection The metabolism of Alogliptin can be decreased when combined with Oritavancin.
Empagliflozin Empagliflozin The risk or severity of hypoglycemia can be increased when Alogliptin is combined with Empagliflozin.
Dulaglutide Injection Dulaglutide Injection The risk or severity of hypoglycemia can be increased when Alogliptin is combined with Dulaglutide.
Edoxaban Edoxaban Alogliptin may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Methamphetamine Methamphetamine Metamfetamine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Tasimelteon Tasimelteon Alogliptin may decrease the excretion rate of Tasimelteon which could result in a higher serum level.
Lanreotide Injection Lanreotide Injection The therapeutic efficacy of Alogliptin can be decreased when used in combination with Lanreotide.
Secukinumab Injection Secukinumab Injection The metabolism of Alogliptin can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The therapeutic efficacy of Alogliptin can be decreased when used in combination with Risperidone.
Insulin Human Inhalation Insulin Human Inhalation Alogliptin may increase the hypoglycemic activities of Insulin human.
Lenvatinib Lenvatinib The metabolism of Alogliptin can be decreased when combined with Lenvatinib.
Naloxegol Naloxegol The metabolism of Alogliptin can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Alogliptin can be decreased when combined with Panobinostat.
Haloperidol Injection Haloperidol Injection The serum concentration of Alogliptin can be increased when it is combined with Haloperidol.
Amiloride Amiloride Amiloride may increase the excretion rate of Alogliptin which could result in a lower serum level and potentially a reduction in efficacy.
Macitentan Macitentan Alogliptin may decrease the excretion rate of Macitentan which could result in a higher serum level.
Rolapitant Rolapitant The metabolism of Alogliptin can be decreased when combined with Rolapitant.
Prednisolone Prednisolone The risk or severity of hyperglycemia can be increased when Prednisolone is combined with Alogliptin.
Brexpiprazole Brexpiprazole The therapeutic efficacy of Alogliptin can be decreased when used in combination with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The therapeutic efficacy of Alogliptin can be decreased when used in combination with Ziprasidone.
Cariprazine Cariprazine The metabolism of Alogliptin can be decreased when combined with Cariprazine.
Penicillin G Procaine Injection Penicillin G Procaine Injection Alogliptin may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection Alogliptin may increase the hypoglycemic activities of Insulin degludec.
Trabectedin Injection Trabectedin Injection The metabolism of Alogliptin can be decreased when combined with Trabectedin.
Ixazomib Ixazomib Alogliptin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lesinurad Lesinurad Alogliptin may decrease the excretion rate of Lesinurad which could result in a higher serum level.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Dexamethasone Injection Dexamethasone Injection The risk or severity of hyperglycemia can be increased when Dexamethasone is combined with Alogliptin.
Brivaracetam Injection Brivaracetam Injection Brivaracetam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cobicistat Cobicistat The metabolism of Alogliptin can be decreased when combined with Cobicistat.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Alogliptin can be decreased when combined with Diphenhydramine.
Furosemide Injection Furosemide Injection The therapeutic efficacy of Alogliptin can be increased when used in combination with Furosemide.
Rucaparib Rucaparib The metabolism of Alogliptin can be decreased when combined with Rucaparib.
Lixisenatide Injection Lixisenatide Injection The risk or severity of hypoglycemia can be increased when Alogliptin is combined with Lixisenatide.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Alogliptin can be decreased when combined with Doxepin.
Deutetrabenazine Deutetrabenazine Alogliptin may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level.
Valbenazine Valbenazine Alogliptin may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Deflazacort Deflazacort The risk or severity of hyperglycemia can be increased when Deflazacort is combined with Alogliptin.
Safinamide Safinamide The metabolism of Alogliptin can be decreased when combined with Safinamide.
Naldemedine Naldemedine Alogliptin may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Midostaurin Midostaurin The metabolism of Alogliptin can be decreased when combined with Midostaurin.
Enasidenib Enasidenib The metabolism of Alogliptin can be decreased when combined with Enasidenib.
Benznidazole Benznidazole Alogliptin may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Delafloxacin Delafloxacin The therapeutic efficacy of Alogliptin can be increased when used in combination with Delafloxacin.
Letermovir Letermovir The metabolism of Letermovir can be decreased when combined with Alogliptin.
Semaglutide Injection Semaglutide Injection The risk or severity of hypoglycemia can be increased when Alogliptin is combined with Semaglutide.
Tetrabenazine Tetrabenazine The metabolism of Alogliptin can be decreased when combined with Tetrabenazine.
Ertugliflozin Ertugliflozin The therapeutic efficacy of Alogliptin can be increased when used in combination with Ertugliflozin.
Buprenorphine Injection Buprenorphine Injection The metabolism of Alogliptin can be decreased when combined with Buprenorphine.
Apalutamide Apalutamide Alogliptin may decrease the excretion rate of Apalutamide which could result in a higher serum level.
Baricitinib Baricitinib Alogliptin may decrease the excretion rate of Baricitinib which could result in a higher serum level.
Lofexidine Lofexidine Lofexidine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Plazomicin Injection Plazomicin Injection Alogliptin may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Eliglustat Eliglustat The metabolism of Alogliptin can be decreased when combined with Eliglustat.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Alogliptin.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Alogliptin.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Alogliptin.
Cannabidiol Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Alogliptin.
Dacomitinib Dacomitinib The metabolism of Alogliptin can be decreased when combined with Dacomitinib.
Stiripentol Stiripentol The metabolism of Alogliptin can be decreased when combined with Stiripentol.
Rifamycin Rifamycin The metabolism of Alogliptin can be decreased when combined with Rifamycin.
Prucalopride Prucalopride Alogliptin may decrease the excretion rate of Prucalopride which could result in a higher serum level.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Alogliptin can be increased when combined with Emapalumab.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Solriamfetol Solriamfetol Alogliptin may decrease the excretion rate of Solriamfetol which could result in a higher serum level.
Triclabendazole Triclabendazole The metabolism of Alogliptin can be decreased when combined with Triclabendazole.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Alogliptin.
Pitolisant Pitolisant The serum concentration of Alogliptin can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The metabolism of Alogliptin can be decreased when combined with Fedratinib.
Phenytoin Injection Phenytoin Injection The metabolism of Alogliptin can be decreased when combined with Phenytoin.
Cenobamate Cenobamate The serum concentration of Alogliptin can be decreased when it is combined with Cenobamate.
Teprotumumab-trbw Injection Teprotumumab-trbw Injection The therapeutic efficacy of Alogliptin can be decreased when used in combination with Teprotumumab.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Alogliptin.
Fenfluramine Fenfluramine The metabolism of Alogliptin can be decreased when combined with Fenfluramine.
Octreotide Octreotide The therapeutic efficacy of Alogliptin can be decreased when used in combination with Octreotide.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Alogliptin can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The therapeutic efficacy of Alogliptin can be decreased when used in combination with Drospirenone.
Viloxazine Viloxazine Alogliptin may decrease the excretion rate of Viloxazine which could result in a higher serum level.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Theophylline Theophylline The metabolism of Alogliptin can be decreased when combined with Theophylline.
Fenoprofen Fenoprofen Fenoprofen may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Indomethacin Indomethacin Indomethacin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Mefenamic Acid Mefenamic Acid Mefenamic acid may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Naproxen Naproxen Naproxen may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Tolmetin Tolmetin Tolmetin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Sulindac Sulindac Sulindac may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Trazodone Trazodone The metabolism of Alogliptin can be decreased when combined with Trazodone.
Isotretinoin Isotretinoin Isotretinoin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Sucralfate Sucralfate Sucralfate may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Hydroxyurea Hydroxyurea The metabolism of Alogliptin can be decreased when combined with Hydroxyurea.
Floxuridine Floxuridine Floxuridine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Metaxalone Metaxalone Metaxalone may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Methotrexate Injection Methotrexate Injection Methotrexate may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Methsuximide Methsuximide The risk or severity of hypoglycemia can be increased when Methsuximide is combined with Alogliptin.
Chlorpromazine Chlorpromazine The metabolism of Alogliptin can be decreased when combined with Chlorpromazine.
Diazepam Diazepam Diazepam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Oxazepam Oxazepam Oxazepam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Flurazepam Flurazepam Flurazepam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Clorazepate Clorazepate Clorazepic acid may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Lorazepam Lorazepam Lorazepam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Carmustine Carmustine Carmustine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Amantadine Amantadine Amantadine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Codeine Codeine Codeine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Bromocriptine Bromocriptine The risk or severity of hypoglycemia can be increased when Bromocriptine is combined with Alogliptin.
Tranylcypromine Tranylcypromine The metabolism of Alogliptin can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Alogliptin can be decreased when combined with Phenelzine.
Procarbazine Procarbazine Procarbazine may increase the hypoglycemic activities of Alogliptin.
Tetracycline Tetracycline Tetracycline may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Prochlorperazine Prochlorperazine The metabolism of Alogliptin can be decreased when combined with Prochlorperazine.
Thioridazine Thioridazine The metabolism of Alogliptin can be decreased when combined with Thioridazine.
Bleomycin Bleomycin Bleomycin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Sulfadiazine Sulfadiazine The therapeutic efficacy of Alogliptin can be increased when used in combination with Sulfadiazine.
Oxycodone Oxycodone The metabolism of Alogliptin can be decreased when combined with Oxycodone.
Methadone Methadone The metabolism of Alogliptin can be decreased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Alogliptin can be decreased when combined with Oxybutynin.
Benztropine Benztropine Benzatropine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Maprotiline Maprotiline Maprotiline may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Ibuprofen Ibuprofen Ibuprofen may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Orphenadrine Orphenadrine The metabolism of Alogliptin can be decreased when combined with Orphenadrine.
Perphenazine Perphenazine The metabolism of Alogliptin can be decreased when combined with Perphenazine.
Azathioprine Azathioprine Azathioprine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Fluphenazine Fluphenazine The metabolism of Alogliptin can be decreased when combined with Fluphenazine.
Phentermine Phentermine The therapeutic efficacy of Alogliptin can be increased when used in combination with Phentermine.
Methylphenidate Methylphenidate Methylphenidate may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Amoxapine Amoxapine The metabolism of Alogliptin can be decreased when combined with Amoxapine.
Sulfasalazine Sulfasalazine Sulfasalazine may increase the hypoglycemic activities of Alogliptin.
Hydrocortisone Hydrocortisone The risk or severity of hyperglycemia can be increased when Hydrocortisone is combined with Alogliptin.
Doxorubicin Doxorubicin The metabolism of Alogliptin can be decreased when combined with Doxorubicin.
Phenazopyridine Phenazopyridine Phenazopyridine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Carbamazepine Carbamazepine Carbamazepine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Methyldopa Methyldopa Methyldopa may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Clonidine Clonidine The metabolism of Alogliptin can be decreased when combined with Clonidine.
Hydralazine Hydralazine Hydralazine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cimetidine Cimetidine The metabolism of Alogliptin can be decreased when combined with Cimetidine.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Warfarin Warfarin Warfarin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Clonazepam Clonazepam Clonazepam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Loperamide Loperamide The risk or severity of hypoglycemia can be increased when Loperamide is combined with Alogliptin.
Promethazine Promethazine The metabolism of Alogliptin can be decreased when combined with Promethazine.
Meclofenamate Meclofenamate Meclofenamic acid may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Nitrofurantoin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Digoxin Digoxin Alogliptin may decrease the excretion rate of Digoxin which could result in a higher serum level.
Chloroquine Chloroquine The metabolism of Alogliptin can be decreased when combined with Chloroquine.
Quinine Quinine The metabolism of Alogliptin can be decreased when combined with Quinine.
Ethosuximide Ethosuximide The risk or severity of hypoglycemia can be increased when Ethosuximide is combined with Alogliptin.
Triamterene Triamterene Triamterene may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Chlorothiazide Chlorothiazide The therapeutic efficacy of Alogliptin can be decreased when used in combination with Chlorothiazide.
Chlorthalidone Chlorthalidone The therapeutic efficacy of Alogliptin can be decreased when used in combination with Chlorthalidone.
Metolazone Metolazone The therapeutic efficacy of Alogliptin can be decreased when used in combination with Metolazone.
Isosorbide Isosorbide Isosorbide may increase the excretion rate of Alogliptin which could result in a lower serum level and potentially a reduction in efficacy.
Secobarbital Secobarbital Secobarbital may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Alogliptin.
Amitriptyline Amitriptyline The metabolism of Alogliptin can be decreased when combined with Amitriptyline.
Imipramine Imipramine The metabolism of Imipramine can be decreased when combined with Alogliptin.
Probenecid Probenecid The therapeutic efficacy of Alogliptin can be increased when used in combination with Probenecid.
Quinidine Quinidine The metabolism of Alogliptin can be decreased when combined with Quinidine.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Alogliptin.
Isoniazid Isoniazid Isoniazid may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Pyrazinamide Pyrazinamide Pyrazinamide may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Disopyramide Disopyramide The risk or severity of hypoglycemia can be increased when Disopyramide is combined with Alogliptin.
Tamoxifen Tamoxifen The metabolism of Alogliptin can be decreased when combined with Tamoxifen.
Butabarbital Butabarbital Butabarbital may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Levothyroxine Levothyroxine The therapeutic efficacy of Alogliptin can be decreased when used in combination with Levothyroxine.
Liothyronine Liothyronine The therapeutic efficacy of Alogliptin can be decreased when used in combination with Liothyronine.
Methimazole Methimazole The metabolism of Alogliptin can be decreased when combined with Methimazole.
Chlorpropamide Chlorpropamide Alogliptin may increase the hypoglycemic activities of Chlorpropamide.
Tolbutamide Tolbutamide Alogliptin may increase the hypoglycemic activities of Tolbutamide.
Tolazamide Tolazamide Alogliptin may increase the hypoglycemic activities of Tolazamide.
Dextromethorphan Dextromethorphan The metabolism of Alogliptin can be decreased when combined with Dextromethorphan.
Niacin Niacin The therapeutic efficacy of Alogliptin can be decreased when used in combination with Niacin.
Baclofen Baclofen The therapeutic efficacy of Alogliptin can be decreased when used in combination with Baclofen.
Clemastine Clemastine The metabolism of Alogliptin can be decreased when combined with Clemastine.
Chlorpheniramine Chlorpheniramine The metabolism of Alogliptin can be decreased when combined with Chlorpheniramine.
Meclizine Meclizine The metabolism of Alogliptin can be decreased when combined with Meclizine.
Ethambutol Ethambutol Ethambutol may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Methyclothiazide Methyclothiazide The therapeutic efficacy of Alogliptin can be decreased when used in combination with Methyclothiazide.
Hydrochlorothiazide Hydrochlorothiazide The therapeutic efficacy of Alogliptin can be decreased when used in combination with Hydrochlorothiazide.
Chlorzoxazone Chlorzoxazone Chlorzoxazone may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Pyridoxine Pyridoxine Pyridoxine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Folic Acid Folic Acid Folic acid may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Danazol Danazol The therapeutic efficacy of Alogliptin can be decreased when used in combination with Danazol.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The therapeutic efficacy of Alogliptin can be increased when used in combination with Propranolol.
Pseudoephedrine Pseudoephedrine The therapeutic efficacy of Alogliptin can be decreased when used in combination with Pseudoephedrine.
Nortriptyline Nortriptyline The metabolism of Alogliptin can be decreased when combined with Nortriptyline.
Spironolactone Spironolactone Spironolactone may increase the excretion rate of Alogliptin which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection Amphotericin B Injection Amphotericin B may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Phytonadione Phytonadione Phylloquinone may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Nadolol Nadolol The therapeutic efficacy of Alogliptin can be increased when used in combination with Nadolol.
Allopurinol Allopurinol Allopurinol may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Fluoxymesterone Fluoxymesterone Fluoxymesterone may increase the hypoglycemic activities of Alogliptin.
Flavoxate Flavoxate Flavoxate may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Colchicine Colchicine Colchicine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cefadroxil Cefadroxil Cefadroxil may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cephalexin Cephalexin Cephalexin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Dacarbazine Dacarbazine Dacarbazine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Acetazolamide Acetazolamide The therapeutic efficacy of Alogliptin can be increased when used in combination with Acetazolamide.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Ketoconazole Ketoconazole The metabolism of Alogliptin can be decreased when combined with Ketoconazole.
Pyrantel Pyrantel Alogliptin may decrease the excretion rate of Pyrantel which could result in a higher serum level.
Captopril Captopril The risk or severity of angioedema can be increased when Captopril is combined with Alogliptin.
Vinblastine Vinblastine The metabolism of Alogliptin can be decreased when combined with Vinblastine.
Ethacrynic Acid Ethacrynic Acid The therapeutic efficacy of Alogliptin can be decreased when used in combination with Etacrynic acid.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Metoprolol Metoprolol The metabolism of Alogliptin can be decreased when combined with Metoprolol.
Hydroxyzine Hydroxyzine The metabolism of Alogliptin can be decreased when combined with Hydroxyzine.
Aspirin Aspirin The risk or severity of hypoglycemia can be increased when Acetylsalicylic acid is combined with Alogliptin.
Salsalate Salsalate Salsalate may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Alprazolam Alprazolam Alprazolam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Temazepam Temazepam Temazepam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Triazolam Triazolam Triazolam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Dicyclomine Dicyclomine Dicyclomine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Propantheline Propantheline Propantheline may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Trimethoprim Trimethoprim Trimethoprim may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Diltiazem Diltiazem The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Alogliptin.
Nifedipine Nifedipine The metabolism of Alogliptin can be decreased when combined with Nifedipine.
Timolol Timolol The therapeutic efficacy of Alogliptin can be increased when used in combination with Timolol.
Verapamil Verapamil The risk or severity of hypoglycemia can be increased when Verapamil is combined with Alogliptin.
Atenolol Atenolol The therapeutic efficacy of Alogliptin can be increased when used in combination with Atenolol.
Pindolol Pindolol The therapeutic efficacy of Alogliptin can be increased when used in combination with Pindolol.
Cisplatin Injection Cisplatin Injection Alogliptin may decrease the excretion rate of Cisplatin which could result in a higher serum level.
Diflunisal Diflunisal Diflunisal may increase the hypoglycemic activities of Alogliptin.
Piroxicam Piroxicam Piroxicam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Bumetanide Bumetanide The therapeutic efficacy of Alogliptin can be increased when used in combination with Bumetanide.
Glyburide Glyburide Alogliptin may increase the hypoglycemic activities of Glyburide.
Glipizide Glipizide Alogliptin may increase the hypoglycemic activities of Glipizide.
Indapamide Indapamide The therapeutic efficacy of Alogliptin can be decreased when used in combination with Indapamide.
Amoxicillin Amoxicillin Amoxicillin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Oxacillin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Pentoxifylline Pentoxifylline Pentoxifylline may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Pentamidine Injection Pentamidine Injection The therapeutic efficacy of Alogliptin can be decreased when used in combination with Pentamidine.
Ceftriaxone Injection Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Labetalol Labetalol The therapeutic efficacy of Alogliptin can be increased when used in combination with Labetalol.
Auranofin Auranofin Auranofin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection The therapeutic efficacy of Alogliptin can be decreased when used in combination with Leuprolide.
Gemfibrozil Gemfibrozil Gemfibrozil may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Ketoprofen Ketoprofen Ketoprofen may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cefotetan Injection Cefotetan Injection Cefotetan may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Pimozide Pimozide The metabolism of Alogliptin can be decreased when combined with Pimozide.
Enalapril Enalapril The risk or severity of angioedema can be increased when Enalapril is combined with Alogliptin.
Flurbiprofen Flurbiprofen Flurbiprofen may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Amiodarone Amiodarone The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Alogliptin.
Aztreonam Injection Aztreonam Injection Aztreonam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Buspirone Buspirone Buspirone may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Lovastatin Lovastatin The metabolism of Alogliptin can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The therapeutic efficacy of Alogliptin can be increased when used in combination with Ciprofloxacin.
Mesalamine Mesalamine Mesalazine may increase the hypoglycemic activities of Alogliptin.
Diclofenac Diclofenac Diclofenac may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Fluoxetine Fluoxetine The serum concentration of Alogliptin can be increased when it is combined with Fluoxetine.
Nimodipine Nimodipine The risk or severity of hypoglycemia can be increased when Nimodipine is combined with Alogliptin.
Clozapine Clozapine The metabolism of Alogliptin can be decreased when combined with Clozapine.
Estazolam Estazolam Estazolam may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Idarubicin Idarubicin The metabolism of Alogliptin can be decreased when combined with Idarubicin.
Ofloxacin Ofloxacin The therapeutic efficacy of Alogliptin can be increased when used in combination with Ofloxacin.
Didanosine Didanosine Didanosine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Pentostatin Injection Pentostatin Injection Pentostatin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Benazepril Benazepril The risk or severity of hypoglycemia can be increased when Benazepril is combined with Alogliptin.
Etodolac Etodolac Etodolac may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Felodipine Felodipine The metabolism of Alogliptin can be decreased when combined with Felodipine.
Fosinopril Fosinopril The risk or severity of angioedema can be increased when Fosinopril is combined with Alogliptin.
Nabumetone Nabumetone Nabumetone may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Quinapril Quinapril The risk or severity of angioedema can be increased when Quinapril is combined with Alogliptin.
Ramipril Ramipril The risk or severity of angioedema can be increased when Ramipril is combined with Alogliptin.
Simvastatin Simvastatin The metabolism of Alogliptin can be decreased when combined with Simvastatin.
Amlodipine Amlodipine The risk or severity of hypoglycemia can be increased when Amlodipine is combined with Alogliptin.
Lisinopril Lisinopril The risk or severity of angioedema can be increased when Lisinopril is combined with Alogliptin.
Oxaprozin Oxaprozin Oxaprozin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Sotalol Sotalol The risk or severity of hypoglycemia can be increased when Sotalol is combined with Alogliptin.
Bisoprolol Bisoprolol The therapeutic efficacy of Alogliptin can be increased when used in combination with Bisoprolol.
Zolpidem Zolpidem The metabolism of Alogliptin can be decreased when combined with Zolpidem.
Doxazosin Doxazosin The metabolism of Alogliptin can be decreased when combined with Doxazosin.
Isradipine Isradipine The risk or severity of hypoglycemia can be increased when Isradipine is combined with Alogliptin.
Omeprazole Omeprazole The metabolism of Alogliptin can be decreased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Alogliptin can be decreased when combined with Cisapride.
Fluvastatin Fluvastatin The metabolism of Alogliptin can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine The metabolism of Alogliptin can be decreased when combined with Venlafaxine.
Fluvoxamine Fluvoxamine The metabolism of Alogliptin can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The risk or severity of hypoglycemia can be increased when Nefazodone is combined with Alogliptin.
Lamotrigine Lamotrigine The risk or severity of hypoglycemia can be increased when Lamotrigine is combined with Alogliptin.
Losartan Losartan The risk or severity of angioedema can be increased when Losartan is combined with Alogliptin.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Tramadol Tramadol Tramadol may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Vinorelbine Injection Vinorelbine Injection The metabolism of Alogliptin can be decreased when combined with Vinorelbine.
Carboplatin Injection Carboplatin Injection Carboplatin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Moexipril Moexipril The risk or severity of angioedema can be increased when Moexipril is combined with Alogliptin.
Lansoprazole Lansoprazole The metabolism of Alogliptin can be decreased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection Ifosfamide may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Nicardipine Nicardipine The metabolism of Alogliptin can be decreased when combined with Nicardipine.
Bupropion Bupropion The metabolism of Alogliptin can be decreased when combined with Bupropion.
Ticlopidine Ticlopidine The metabolism of Alogliptin can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The therapeutic efficacy of Alogliptin can be decreased when used in combination with Saquinavir.
Nisoldipine Nisoldipine The risk or severity of hypoglycemia can be increased when Nisoldipine is combined with Alogliptin.
Lamivudine Lamivudine Lamivudine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Acarbose Acarbose The risk or severity of hypoglycemia can be increased when Acarbose is combined with Alogliptin.
Glimepiride Glimepiride Alogliptin may increase the hypoglycemic activities of Glimepiride.
Gemcitabine Injection Gemcitabine Injection Gemcitabine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Indinavir Indinavir The therapeutic efficacy of Alogliptin can be decreased when used in combination with Indinavir.
Ritonavir Ritonavir The serum concentration of Alogliptin can be increased when it is combined with Ritonavir.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Meropenem Injection Meropenem Injection Meropenem may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Clomipramine Clomipramine The metabolism of Alogliptin can be decreased when combined with Clomipramine.
Fosfomycin Fosfomycin Fosfomycin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Mirtazapine Mirtazapine The metabolism of Alogliptin can be decreased when combined with Mirtazapine.
Trandolapril Trandolapril The risk or severity of angioedema can be increased when Trandolapril is combined with Alogliptin.
Topiramate Topiramate Topiramate may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Valsartan Valsartan The risk or severity of angioedema can be increased when Valsartan is combined with Alogliptin.
Insulin Lispro Injection Insulin Lispro Injection Alogliptin may increase the hypoglycemic activities of Insulin lispro.
Pramipexole Pramipexole Pramipexole may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Donepezil Donepezil The metabolism of Alogliptin can be decreased when combined with Donepezil.
Nelfinavir Nelfinavir The metabolism of Alogliptin can be decreased when combined with Nelfinavir.
Carvedilol Carvedilol The therapeutic efficacy of Alogliptin can be increased when used in combination with Carvedilol.
Nilutamide Nilutamide Nilutamide may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Flutamide Flutamide Flutamide may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Selegiline Selegiline The metabolism of Alogliptin can be decreased when combined with Selegiline.
Bicalutamide Bicalutamide The metabolism of Alogliptin can be decreased when combined with Bicalutamide.
Sertraline Sertraline The risk or severity of hypoglycemia can be increased when Sertraline is combined with Alogliptin.
Propafenone Propafenone The therapeutic efficacy of Alogliptin can be increased when used in combination with Propafenone.
Tamsulosin Tamsulosin The therapeutic efficacy of Alogliptin can be increased when used in combination with Tamsulosin.
Quetiapine Quetiapine The therapeutic efficacy of Alogliptin can be decreased when used in combination with Quetiapine.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Cetirizine Cetirizine Cetirizine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Paroxetine Paroxetine The metabolism of Alogliptin can be decreased when combined with Paroxetine.
Tolcapone Tolcapone Tolcapone may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Citalopram Citalopram The metabolism of Alogliptin can be decreased when combined with Citalopram.
Capecitabine Capecitabine Capecitabine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Abacavir Abacavir Abacavir may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Sildenafil Sildenafil The metabolism of Alogliptin can be decreased when combined with Sildenafil.
Celecoxib Celecoxib The metabolism of Alogliptin can be decreased when combined with Celecoxib.
Rosiglitazone Rosiglitazone The metabolism of Alogliptin can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine Tolterodine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Oseltamivir Oseltamivir Oseltamivir may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Balsalazide Balsalazide Balsalazide may increase the hypoglycemic activities of Alogliptin.
Nateglinide Nateglinide The risk or severity of hypoglycemia can be increased when Nateglinide is combined with Alogliptin.
Galantamine Galantamine The metabolism of Alogliptin can be decreased when combined with Galantamine.
Rabeprazole Rabeprazole Rabeprazole may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Terbinafine Terbinafine The metabolism of Alogliptin can be decreased when combined with Terbinafine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists

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