Benazepril and Hydrochlorothiazide
Benazepril and hydrochlorothiazide is a combination ACE inhibitor and diuretic used to treat high blood pressure (hypertension) in adults.
🧬 Where this information comes from Click to expand
The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 7 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →
⚠️ FDA Boxed Warning — the FDA’s strongest safety alert ▾
Do not take this medicine if you are pregnant. Benazepril and hydrochlorothiazide can cause serious harm — and even death — to an unborn baby, particularly when taken during the second or third trimester. If you find out you are pregnant at any point while taking this medicine, stop it as soon as possible and call your doctor right away to discuss safer alternatives for managing your blood pressure during pregnancy.
📖 Benazepril and Hydrochlorothiazide: Patient Information Guide
A plain-language walkthrough of Benazepril and Hydrochlorothiazide — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.
🎯What it's used for▾
Benazepril and hydrochlorothiazide is a fixed-dose combination tablet approved to treat high blood pressure (hypertension).
- Indicated for hypertension in adults who need more than one medicine to control their blood pressure
- Lotensin HCT is used when benazepril alone or hydrochlorothiazide alone does not control blood pressure adequately
- The combination tablet (Benazepril Hydrochloride and Hydrochlorothiazide or Lotensin HCT) may replace separately taken tablets once each component's dose has been established
- Not approved as a first treatment choice for someone newly diagnosed with high blood pressure
⚙️How it works▾
Benazepril blocks an enzyme called ACE (angiotensin-converting enzyme), which normally converts a protein in the blood into angiotensin II — a substance that tightens blood vessels and prompts the body to retain sodium. By blocking this step, benazepril keeps blood vessels relaxed and reduces fluid retention, lowering blood pressure. Hydrochlorothiazide is a thiazide diuretic that acts on the kidneys to excrete extra sodium and water, reducing blood volume. One useful bonus of combining them: thiazide diuretics tend to lower potassium levels, while ACE inhibitors tend to raise them slightly, so the two effects partly cancel each other out.
💊How it's taken▾
Both branded and generic versions of this combination tablet are taken once daily by mouth. Food does not meaningfully affect absorption, so you can take it with or without a meal. Your prescriber may increase the dose after 2 to 3 weeks if your blood pressure isn't at goal.
- Take at the same time every day to keep blood pressure consistently controlled
- If you miss a dose, follow the instructions on your prescription label or ask your pharmacist
- Do not adjust or stop the dose on your own — always check with your prescriber first
🤒Side effects — in detail▾
Most side effects are mild and often improve with time. The most commonly reported ones include:
- Dizziness or lightheadedness, especially when standing up quickly
- Fatigue or tiredness
- Headache
- Dry, persistent cough (a known ACE inhibitor effect)
- Nausea
- Vertigo
- Muscle stiffness or tension
- Drowsiness
Seek emergency help right away if you notice sudden swelling of the face, lips, tongue, or throat, or sudden eye pain with vision changes — these are rare but serious reactions that require immediate treatment.
⚠️Warnings & precautions▾
- Fetal harm (pregnancy): This medicine can cause serious injury or death to a developing baby, especially in the second and third trimesters. Stop it immediately if you become pregnant and contact your doctor.
- Angioedema (dangerous swelling): Swelling of the face, tongue, throat, or gut can be life-threatening. Black patients and those also taking mTOR inhibitors or neprilysin inhibitors face higher risk. Call 911 if swelling occurs.
- Low blood pressure (hypotension): Most likely in people who are dehydrated, on other blood pressure medicines, or have heart failure. Rise slowly from sitting or lying down.
- Kidney function: This combination can worsen kidney function, especially in people with kidney artery narrowing, chronic kidney disease, or heart failure. Routine monitoring is important.
- Acute angle-closure glaucoma: Hydrochlorothiazide can trigger sudden, painful vision changes that may lead to permanent vision loss if not treated immediately. Get emergency eye care if this happens.
- Liver injury: ACE inhibitors are rarely linked to serious liver problems. Contact your doctor promptly if you develop jaundice (yellowing of skin or eyes).
- Lupus: Hydrochlorothiazide may trigger or worsen systemic lupus erythematosus.
- Skin cancer risk: Long-term use of hydrochlorothiazide has been linked to a small increased risk of squamous cell skin cancer, particularly in white patients with high cumulative doses. Protect your skin from the sun and report any new or changing skin lesions to your doctor.
🔀What it interacts with▾
This medicine interacts with several common drugs and substances — always give your pharmacist and prescriber a full list of everything you take.
- Sacubitril/valsartan (Entresto): Must not be combined; wait at least 36 hours when switching — greatly raises angioedema risk
- Aliskiren: Contraindicated in people with diabetes; avoid if kidney function is reduced
- Lithium: Levels in the blood can rise to toxic levels; close monitoring required
- NSAIDs/COX-2 inhibitors (ibuprofen, naproxen, celecoxib): Can blunt the blood-pressure benefit and may worsen kidney function
- Potassium supplements or potassium-sparing diuretics: Can push potassium too high; monitor levels regularly
- mTOR inhibitors (sirolimus, everolimus, temsirolimus): Increased risk of dangerous swelling (angioedema)
- Alcohol, barbiturates, narcotics: Can amplify blood-pressure-lowering effects and cause dizziness when standing
- Cholestyramine or colestipol (bile acid resins): Significantly reduce hydrochlorothiazide absorption — take hydrochlorothiazide at least 4 hours before or 4–6 hours after these medicines
- Digoxin: Low potassium caused by hydrochlorothiazide can increase the risk of digoxin toxicity
- Injectable gold: Rare flushing, nausea, and low blood pressure reactions have been reported
- Antidiabetic medicines: Dose adjustments may be needed since hydrochlorothiazide can raise blood sugar
This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.
📋Before taking it▾
- Pregnancy: Do not take this medicine if you are pregnant or may become pregnant — it can cause serious fetal harm or death
- History of angioedema: Do not take if you have ever had swelling reactions with an ACE inhibitor or hereditary angioedema
- No urination (anuria): Contraindicated — do not take if you are not producing urine at all
- Allergy: Do not take if you are allergic to benazepril, any ACE inhibitor, hydrochlorothiazide, or other sulfonamide drugs
- Kidney disease: Requires close monitoring; dose adjustment may be needed in severe impairment
- Heart failure: Extra caution and close monitoring for low blood pressure and kidney changes are needed
- Liver disease: Use with caution; benazepril levels are not significantly altered by cirrhosis, but the combination should be used carefully
- Diabetes: Cannot be combined with aliskiren; hydrochlorothiazide may affect blood sugar control
- Lupus: Hydrochlorothiazide may worsen systemic lupus erythematosus
- Sulfonamide or penicillin allergy: May increase risk of the rare acute eye (angle-closure glaucoma) reaction from hydrochlorothiazide
- Dialysis patients: Anaphylactoid reactions have been reported with ACE inhibitors in people dialyzed with high-flux membranes
- People undergoing allergy desensitization: Life-threatening reactions have been reported when ACE inhibitors are taken during bee/wasp venom desensitization therapy
🚑If you take too much▾
Taking too much of this medicine is most likely to cause a dangerous drop in blood pressure (causing faintness or collapse), and the hydrochlorothiazide component can lead to dehydration and low levels of electrolytes like potassium, chloride, and sodium. If you suspect an overdose, stop the medicine and seek medical attention immediately. Treatment is supportive — restoring fluids and correcting electrolyte levels — and dialysis is generally not effective at removing the active drug.
📡Pharmacodynamics — effects in the body▾
Benazepril blocks ACE activity by 80–90% for at least 24 hours after a dose of 10 mg or more. Hydrochlorothiazide begins producing urine output within about 2 hours of an oral dose, peaks around 4 hours, and the effect lasts roughly 6 to 12 hours. Together, the two medicines potentiate (strengthen) the blood-pressure-lowering effect of other antihypertensive drugs, so extra care is needed if this combination is used alongside other agents that lower blood pressure.
🔬Pharmacokinetics — how your body processes it▾
After you swallow a tablet, benazepril is absorbed quickly and converted mainly in the liver to its active form, benazeprilat, which reaches peak levels within 1 to 4 hours depending on whether you've eaten. Benazeprilat has an effective accumulation half-life of about 10 to 11 hours, meaning steady blood levels are typically reached within 2 to 3 days of once-daily dosing. Hydrochlorothiazide reaches peak levels in 2 to 5 hours and is mostly cleared unchanged by the kidneys, with an elimination half-life of about 10 hours. Both components are cleared primarily by the kidneys, so reduced kidney function slows their removal and may require extra monitoring or dose adjustment.
📦How to store it▾
Store at 20° to 25°C (68° to 77°F) . Protect from moisture and light. Dispense in a tight, light-resistant container as defined in the USP.
📄 Written from Benazepril and Hydrochlorothiazide’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →
🩺 Pharmacist Counseling Corner
Quick, plain-English answers to the questions patients ask most about Benazepril and Hydrochlorothiazide — the kind of thing our pharmacy team would talk through with you at the counter.
What exactly is this medicine for, and why do I need two drugs in one pill? ▾
Can I take this pill with food, and does it matter what time of day I take it? ▾
I've heard ACE inhibitors can cause a cough. Is that true, and what should I do if I get one? ▾
What symptoms should make me call for emergency help right away? ▾
Is it safe to take this medicine if I'm trying to get pregnant or I just found out I'm pregnant? ▾
Are there common medicines or supplements I should avoid while taking this? ▾
Is Benazepril and Hydrochlorothiazide available over the counter? ▾
When was Benazepril and Hydrochlorothiazide first available? ▾
Who makes Benazepril and Hydrochlorothiazide? ▾
💬 Answers drafted from Benazepril and Hydrochlorothiazide’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →
🧰 Keep exploring
💊 How Benazepril and Hydrochlorothiazide comes
Benazepril and Hydrochlorothiazide is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.
Tablet
How this form is used
- Treats high blood pressure (hypertension) in adults
- Lotensin HCT is used when blood pressure is not adequately controlled by benazepril alone or by hydrochlorothiazide alone
- Benazepril Hydrochloride and Hydrochlorothiazide tablets may replace separately taken benazepril and hydrochlorothiazide once the right doses of each have been established
- Not intended as a first (initial) treatment for high blood pressure
- Take by mouth once daily, with or without food
- Lotensin HCT: your doctor may increase your dose after 2 to 3 weeks if your blood pressure goal has not been reached
- Benazepril Hydrochloride and Hydrochlorothiazide tablets: follow your prescriber's directions exactly — do not adjust your dose on your own
- Stop taking and contact your doctor immediately if you become pregnant
📊 Benazepril and Hydrochlorothiazide across the U.S. market
How Benazepril and Hydrochlorothiazide appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.
Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
📈 How widely Benazepril and Hydrochlorothiazide is used
A general measure of how commonly Benazepril and Hydrochlorothiazide is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.
Think of this as a proxy for how widely Benazepril and Hydrochlorothiazide is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.
How commonly is Benazepril and Hydrochlorothiazide prescribed? Of the 1,596 medications we measure, Benazepril and Hydrochlorothiazide ranks #801 by Medicaid prescriptions — more than 50% of them.
Utilization by Benazepril and Hydrochlorothiazide product
Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.
benazepril hydrochloride 20 MG / hydrochlorothiazide 25 MG Oral Tablet Most dispensed
Summed across the 4 of 14 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 898372
benazepril hydrochloride 20 MG / hydrochlorothiazide 12.5 MG Oral Tablet
Summed across the 4 of 21 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 898367
benazepril hydrochloride 10 MG / hydrochlorothiazide 12.5 MG Oral Tablet
Summed across the 3 of 15 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 898362
benazepril hydrochloride 5 MG / hydrochlorothiazide 6.25 MG Oral Tablet
Summed across the 3 of 6 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 898378
Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.
Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Benazepril and Hydrochlorothiazide, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 14 of 56 listed Benazepril and Hydrochlorothiazide NDCs with Medicaid activity.
🔍 Compare Benazepril and Hydrochlorothiazide products
A representative set of FDA-listed product records for Benazepril and Hydrochlorothiazide — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)
| Strength | Route | Manufacturer / Labeler | Category ⓘ | Details |
|---|---|---|---|---|
| 💊Tablet | ||||
| BENAZEPRIL HYDROCHLORIDE 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg | Oral | Advagen Pharma Ltd | NDA AUTHORIZED GENERIC | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg | Oral | Advagen Pharma Ltd | NDA AUTHORIZED GENERIC | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg | Oral | Advagen Pharma Ltd | NDA AUTHORIZED GENERIC | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 5 mg/1; HYDROCHLOROTHIAZIDE 6.25 mg | Oral | ANI Pharmaceuticals, Inc. | ANDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg | Oral | ANI Pharmaceuticals, Inc. | ANDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg | Oral | ANI Pharmaceuticals, Inc. | ANDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg | Oral | ANI Pharmaceuticals, Inc. | ANDA | View NDC → |
| 5; 6.25 mg/1; mg | Oral | ANI Pharmaceuticals, Inc. | ANDA | View NDC → |
| 10; 12.5 mg/1; mg | Oral | ANI Pharmaceuticals, Inc. | ANDA | View NDC → |
| 20; 12.5 mg/1; mg | Oral | ANI Pharmaceuticals, Inc. | ANDA | View NDC → |
| 20; 25 mg/1; mg | Oral | ANI Pharmaceuticals, Inc. | ANDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg | Oral | Bryant Ranch Prepack | NDA AUTHORIZED GENERIC | View NDC → |
| 20; 12.5 mg/1; mg | Oral | Bryant Ranch Prepack | ANDA | View NDC → |
| 5; 6.25 mg/1; mg | Oral | Eon Labs, Inc. × 2 listings | ANDA | View NDC → |
| 10; 12.5 mg/1; mg | Oral | Eon Labs, Inc. × 2 listings | ANDA | View NDC → |
| 20; 12.5 mg/1; mg | Oral | Eon Labs, Inc. × 2 listings | ANDA | View NDC → |
| 20; 25 mg/1; mg | Oral | Eon Labs, Inc. × 2 listings | ANDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 5 mg/1; HYDROCHLOROTHIAZIDE 6.25 mg | Oral | Glenmark Pharmaceuticals Inc., USA | ANDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg | Oral | Glenmark Pharmaceuticals Inc., USA | ANDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg | Oral | Glenmark Pharmaceuticals Inc., USA | ANDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg | Oral | Glenmark Pharmaceuticals Inc., USA | ANDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg | Oral | Padagis US LLC | NDA AUTHORIZED GENERIC | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg | Oral | Padagis US LLC | NDA AUTHORIZED GENERIC | View NDC → |
| 10; 12.5 mg/1; mg | Oral | Padagis US LLC × 2 listings | NDA AUTHORIZED GENERIC | View NDC → |
| 20; 12.5 mg/1; mg | Oral | Padagis US LLC × 2 listings | NDA AUTHORIZED GENERIC | View NDC → |
| 20; 25 mg/1; mg | Oral | Padagis US LLC × 2 listings | NDA AUTHORIZED GENERIC | View NDC → |
| 10; 12.5 mg/1; mg | Oral | Rising Pharmaceuticals, Inc. | NDA AUTHORIZED GENERIC | View NDC → |
| 20; 12.5 mg/1; mg | Oral | Rising Pharmaceuticals, Inc. | NDA AUTHORIZED GENERIC | View NDC → |
| 20; 25 mg/1; mg | Oral | Rising Pharmaceuticals, Inc. | NDA AUTHORIZED GENERIC | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 5 mg/1; HYDROCHLOROTHIAZIDE 6.25 mg | Oral | Sandoz Inc | ANDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg | Oral | Sandoz Inc | ANDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg | Oral | Sandoz Inc | ANDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg | Oral | Sandoz Inc | ANDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg | Oral | Validus Pharmaceuticals LLC | NDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg | Oral | Validus Pharmaceuticals LLC | NDA | View NDC → |
| BENAZEPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg | Oral | Validus Pharmaceuticals LLC | NDA | View NDC → |
| 10; 12.5 mg/1; mg | Oral | Validus Pharmaceuticals LLC × 2 listings | NDA | View NDC → |
| 20; 12.5 mg/1; mg | Oral | Validus Pharmaceuticals LLC × 2 listings | NDA | View NDC → |
| 20; 25 mg/1; mg | Oral | Validus Pharmaceuticals LLC × 2 listings | NDA | View NDC → |
Showing 49 of 49 products — FDA National Drug Code Directory. See every product, package size and price: browse all 49 Benazepril and Hydrochlorothiazide NDCs →
📈 What people report — real-world data (FDA FAERS)
After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Benazepril and Hydrochlorothiazide — a signal of what to watch for, not proof the drug caused it.
Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Benazepril and Hydrochlorothiazide in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.
🏛️ The road to your pharmacy
How Benazepril and Hydrochlorothiazide went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.
Source: Drugs@FDA.
🚨 Recall history
A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.
Source: openFDA drug enforcement (recall) reports.
RxNorm Concept Web — From Ingredient to Every Form and Strength
This page starts with one exact multiple-ingredient concept (MIN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). A product with a different ingredient combination belongs on a different page.
RxCUI 214287 1 dose form · 4 strengths
-
Dose form (SCDF) Oral Tablet RxCUI 371000In current FDA listingsClinical drug / strength (SCD) benazepril hydrochloride 10 MG / hydrochlorothiazide 12.5 MGRxCUI 898362benazepril hydrochloride 20 MG / hydrochlorothiazide 12.5 MGRxCUI 898367benazepril hydrochloride 20 MG / hydrochlorothiazide 25 MGRxCUI 898372benazepril hydrochloride 5 MG / hydrochlorothiazide 6.25 MGRxCUI 898378
Look up RxCUI 214287 in the RxCUI Atlas →
RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.
📦 Supply & shortage status
Whether Benazepril and Hydrochlorothiazide is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.
Source: openFDA, from the FDA Drug Shortages database.
🏷️ Sold under these brand names
🏭 Manufacturers & labelers
RxNorm drug class
Benazepril and Hydrochlorothiazide belongs to the Angiotensin Converting Enzyme Inhibitor class.
Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.
🔬 Where this comes from
Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.
How we combine label and product data
HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 7 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.
For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Validus Pharmaceuticals LLC is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.
This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.