Buprenorphine Injection

Buprenorphine extended-release injection is used to treat opioid dependence (addiction to opioid drugs, including heroin and narcotic painkillers) in people who have received buccal or sublingual buprenorphine for at least 7 days. Buprenorphine extended-release injection is in a class of medications called opiate partial agonists. It works to prevent withdrawal symptoms when someone stops taking opioid drugs by producing similar effects to these drugs.

Buprenorphine extended-release (long-acting) injection comes as a solution (liquid) to be injected subcutaneously (just under the skin) by a health care provider into the stomach area. It is usually given once monthly with at least 26 days in between doses. Each buprenorphine injection slowly releases the drug into your body over a month.

After you receive a dose of buprenorphine extended-release injection, you may notice a lump at the injection site for several weeks, but it should decrease in size over time. Do not rub or massage the injection site. Be sure that your belt or waistband does not put pressure on the place where the medication was injected.

Your doctor may increase or decrease your dose depending on how well the medication works for you, and any side effects you experience. Be sure to tell your doctor how you are feeling during your treatment with buprenorphine extended-release injection.

If buprenorphine extended-release is to be discontinued, your doctor will probably decrease your dose gradually. You may experience withdrawal symptoms including restlessness, teary eyes, sweating, chills, widening of the pupils (black circles in the middle of the eyes), irritability, anxiety, backache, weakness, stomach cramps, difficulty falling asleep or staying asleep, nausea, loss of appetite, vomiting, diarrhea, fast breathing, or fast heartbeat. These withdrawal symptoms may occur 1 month or longer after your last buprenorphine extended-release injection dose.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before receiving buprenorphine injection,

• tell your doctor and pharmacist if you are allergic to buprenorphine, any other medications, or any of the ingredients in buprenorphine injection. Ask your pharmacist or check the Medication Guide for a list of the ingredients.

• tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antihistamines; benzodiazepines such as such as alprazolam (Xanax), chlordiazepoxide (Librium, in Librax), clonazepam (Klonopin), diazepam (Valium), estazolam, flurazepam, lorazepam (Ativan), oxazepam, temazepam (Restoril), triazolam (Halcion); carbamazepine (Carbatrol, Tegretol, Teril, others); diuretics ('water pills'); erythromycin (E.E.S., Eryc, PCE, others); HIV medications such as atazanavir (Reyataz, in Evotaz), delavirdine (Rescriptor), efavirenz (Sustiva, in Atripla), etravirine (Intelence), indinavir (Crixivan), nevirapine (Viramune), ritonavir (Norvir, in Kaletra), and saquinavir (Invirase); certain medications for irregular heartbeat including amiodarone (Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), procainamide (Procanbid), quinidine (in Nuedexta), and sotalol (Betapace, Betapace AF, Sorine); medications for glaucoma, mental illness, motion sickness, Parkinson's disease, ulcers, or urinary problems; ketoconazole, other medications for pain; medications for migraine headaches such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, in Treximet), and zolmitriptan (Zomig); muscle relaxants; phenobarbital; phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rimactane); sedatives; sleeping pills; 5HT3 serotonin blockers such as alosetron (Lotronex), dolasetron (Anzemet), granisetron (Kytril), ondansetron (Zofran, Zuplenz), or palonosetron (Aloxi); selective serotonin-reuptake inhibitors such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Prozac, Pexeva), and sertraline (Zoloft); serotonin and norepinephrine reuptake inhibitors such as duloxetine (Cymbalta), desvenlafaxine (Khedezla, Pristiq), milnacipran (Savella), and venlafaxine (Effexor); tramadol; tranquilizers; trazodone; or tricyclic antidepressants ('mood elevators') such as amitriptyline, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil). Also tell your doctor or pharmacist if you are taking or receiving the following monoamine oxidase (MAO) inhibitors or if you have stopped taking them within the past two weeks: isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with buprenorphine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

• tell your doctor if you or a family member drinks or has ever drunk large amounts of alcohol or have or have ever had prolonged QT syndrome (condition that increases the risk of developing an irregular heartbeat that may cause loss of consciousness or sudden death). Also, tell your doctor if you have or have ever had low levels of potassium or magnesium in the blood; heart failure; a slow or irregular heartbeat; chronic obstructive pulmonary disease (COPD; a group of diseases that affect the lungs and airways); other lung diseases; a head injury; a brain tumor; any condition that increases the amount of pressure in your brain; adrenal problems such as Addison's disease (condition in which the adrenal gland produces less hormone than normal); benign prostatic hypertrophy (BPH, enlargement of the prostate gland); difficulty urinating; hallucinations (seeing things or hearing voices that do not exist); a curve in the spine that makes it hard to breathe; or thyroid, gallbladder, or liver disease.

• tell your doctor if you are pregnant or plan to become pregnant. If you receive buprenorphine extended-release injection regularly during your pregnancy, your baby could experience life-threatening withdrawal symptoms after birth. Tell your baby's doctor right away if your baby experiences any of the following symptoms: irritability, hyperactivity, abnormal sleep, high-pitched cry, uncontrollable shaking of a part of the body, vomiting, diarrhea, or failure to gain weight.

• tell your doctor if you are breastfeeding. Tell your baby's doctor right away if your baby is sleepier than usual or has trouble breathing while you are receiving this medication.

• you should know that this medication may decrease fertility in men and women. Talk to your doctor about the risks of using buprenorphine extended-release injection.

• if you are having surgery, including dental surgery, tell the doctor or dentist that you are receiving buprenorphine extended-release injection.

• you should know that buprenorphine extended-release injection may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.

• you should not drink alcohol or use street drugs during your treatment. Drinking alcohol, taking prescription or nonprescription medications that contain alcohol, or using street drugs during your treatment with buprenorphine injection increases the risk that you will experience serious and life-threatening breathing problems.

• you should know that buprenorphine may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

• you should know that buprenorphine may cause constipation. Talk to your doctor about changing your diet or using other medications to prevent or treat constipation while you are using buprenorphine injection.

Unless your doctor tells you otherwise, continue your normal diet.

If you miss a scheduled buprenorphine extended-release injection dose, you should call your doctor to receive the dose as soon as possible. Your next dose should be given at least 26 days later.

• Buprenorphine extended-release injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea

  • vomiting

  • headache

  • fatigue

  • pain, itching, swelling, discomfort, redness, bruising, or bumps in the injection site

• Some side effects can be serious. If you experience any of these symptoms call your doctor immediately or get emergency medical treatment:

  • difficulty breathing

  • agitation, hallucinations (seeing things or hearing voices that do not exist), fever, sweating, confusion, fast heartbeat, shivering, slurred speech, severe muscle stiffness or twitching, loss of coordination, nausea, vomiting, or diarrhea

  • nausea, vomiting, loss of appetite, weakness, or dizziness

  • inability to get or keep an erection

  • irregular menstruation

  • decreased sexual desire

  • rash

  • hives

  • itching

  • slurred speech

  • blurred vision

  • changes in heartbeat

  • pain in the upper right part of the stomach

  • yellowing of the skin or eyes

  • dark-colored urine

  • light-colored stools

• Buprenorphine extended-release injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.

• If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

• narrowing or widening of the pupils (black circles in the center of the eye)

• slowed or difficulty breathing

• extreme sleepiness or drowsiness

• coma (loss of consciousness for a period of time)

• slow heartbeat

Before having any laboratory test (especially those that involve methylene blue), tell your doctor and the laboratory personnel that you are using buprenorphine injection.

In the case of an emergency, a family member or caregiver should tell the emergency medical staff that you are physically dependent on an opioid and are receiving treatment with buprenorphine extended-release injection.

Buprenorphine extended-release injection is a controlled substance. Be sure to schedule appointments with your doctor on a regular basis to receive your injections. Ask your pharmacist if you have any questions.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug	Interaction
Repaglinide	Repaglinide The metabolism of Buprenorphine can be decreased when combined with Repaglinide.
Montelukast	Montelukast The metabolism of Buprenorphine can be decreased when combined with Montelukast.
Leflunomide	Leflunomide Buprenorphine may decrease the excretion rate of Leflunomide which could result in a higher serum level.
Delavirdine	Delavirdine The metabolism of Buprenorphine can be decreased when combined with Delavirdine.
Nevirapine	Nevirapine The metabolism of Buprenorphine can be decreased when combined with Nevirapine.
Atorvastatin	Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Buprenorphine.
Dolasetron	Dolasetron Dolasetron may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Aminophylline	Aminophylline The metabolism of Aminophylline can be decreased when combined with Buprenorphine.
Bisacodyl	Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Buprenorphine.
Candesartan	Candesartan The metabolism of Buprenorphine can be decreased when combined with Candesartan.
Cilostazol	Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Buprenorphine.
Clopidogrel	Clopidogrel Buprenorphine can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Diphenoxylate	Diphenoxylate Diphenoxylate may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Erythromycin and Sulfisoxazole	Erythromycin and Sulfisoxazole The metabolism of Buprenorphine can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives)	Estrogen and Progestin (Oral Contraceptives) Buprenorphine may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate	Fenofibrate The metabolism of Buprenorphine can be decreased when combined with Fenofibrate.
Guanfacine	Guanfacine Guanfacine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Magnesium Hydroxide	Magnesium Hydroxide The therapeutic efficacy of Magnesium hydroxide can be decreased when used in combination with Buprenorphine.
Magnesium Oxide	Magnesium Oxide The therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Buprenorphine.
Naratriptan	Naratriptan Naratriptan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Paregoric	Paregoric Morphine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Penbutolol	Penbutolol The metabolism of Buprenorphine can be decreased when combined with Acebutolol.
Pentazocine	Pentazocine Pentazocine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Polyethylene glycol-electrolyte solution (PEG-ES)	Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Buprenorphine.
Potassium	Potassium The therapeutic efficacy of Potassium can be decreased when used in combination with Buprenorphine.
Psyllium	Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Buprenorphine.
Ranitidine	Ranitidine The metabolism of Buprenorphine can be decreased when combined with Ranitidine.
Reserpine	Reserpine Reserpine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Rizatriptan	Rizatriptan Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Sumatriptan	Sumatriptan Sumatriptan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Tacrolimus	Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Buprenorphine.
Tizanidine	Tizanidine Tizanidine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Triamcinolone	Triamcinolone The metabolism of Buprenorphine can be increased when combined with Triamcinolone.
Zolmitriptan	Zolmitriptan Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Fluconazole Injection	Fluconazole Injection The metabolism of Buprenorphine can be decreased when combined with Fluconazole.
Hydromorphone Injection	Hydromorphone Injection Hydromorphone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Meperidine Injection	Meperidine Injection Meperidine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Metoclopramide Injection	Metoclopramide Injection The therapeutic efficacy of Buprenorphine can be decreased when used in combination with Metoclopramide.
Metronidazole Injection	Metronidazole Injection The metabolism of Buprenorphine can be decreased when combined with Metronidazole.
Morphine Injection	Morphine Injection Morphine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Zidovudine Injection	Zidovudine Injection The metabolism of Buprenorphine can be increased when combined with Zidovudine.
Altretamine	Altretamine The risk or severity of serotonin syndrome and opioid toxicity can be increased when Buprenorphine is combined with Amphetamine.
Cyclosporine	Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Buprenorphine.
Ondansetron	Ondansetron Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Granisetron	Granisetron Granisetron may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Torsemide	Torsemide The metabolism of Buprenorphine can be decreased when combined with Torasemide.
Olanzapine	Olanzapine Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Alosetron	Alosetron Alosetron may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Dofetilide	Dofetilide The metabolism of Dofetilide can be decreased when combined with Buprenorphine.
Entacapone	Entacapone Entacapone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Hydroxychloroquine	Hydroxychloroquine The metabolism of Buprenorphine can be decreased when combined with Hydroxychloroquine.
Meloxicam	Meloxicam The metabolism of Buprenorphine can be decreased when combined with Meloxicam.
Oxcarbazepine	Oxcarbazepine Oxcarbazepine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Pantoprazole	Pantoprazole The metabolism of Pantoprazole can be decreased when combined with Buprenorphine.
Zaleplon	Zaleplon Zaleplon may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Anakinra	Anakinra The metabolism of Buprenorphine can be increased when combined with Anakinra.
Desloratadine	Desloratadine Desloratadine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Linezolid	Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Buprenorphine.
Trimipramine	Trimipramine Trimipramine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Etanercept Injection	Etanercept Injection The metabolism of Buprenorphine can be increased when combined with Etanercept.
Glycopyrrolate	Glycopyrrolate The risk or severity of adverse effects can be increased when Buprenorphine is combined with Glycopyrronium.
Modafinil	Modafinil The metabolism of Buprenorphine can be increased when combined with Modafinil.
Tenofovir	Tenofovir The metabolism of Tenofovir can be decreased when combined with Buprenorphine.
Sirolimus	Sirolimus The metabolism of Sirolimus can be decreased when combined with Buprenorphine.
Dutasteride	Dutasteride The metabolism of Dutasteride can be decreased when combined with Buprenorphine.
Epinephrine Injection	Epinephrine Injection The metabolism of Buprenorphine can be decreased when combined with Epinephrine.
Eplerenone	Eplerenone The therapeutic efficacy of Buprenorphine can be decreased when used in combination with Eplerenone.
Escitalopram	Escitalopram Escitalopram may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Zonisamide	Zonisamide Zonisamide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Adalimumab Injection	Adalimumab Injection The metabolism of Buprenorphine can be increased when combined with Adalimumab.
Aripiprazole	Aripiprazole Aripiprazole may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Atomoxetine	Atomoxetine Atomoxetine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Dexmethylphenidate	Dexmethylphenidate Dexmethylphenidate may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Ezetimibe	Ezetimibe Buprenorphine may decrease the excretion rate of Ezetimibe which could result in a higher serum level.
Atazanavir	Atazanavir The metabolism of Atazanavir can be decreased when combined with Buprenorphine.
Almotriptan	Almotriptan Almotriptan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Eletriptan	Eletriptan Eletriptan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Mefloquine	Mefloquine The metabolism of Buprenorphine can be decreased when combined with Mefloquine.
Polyethylene Glycol 3350	Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Buprenorphine.
Rosuvastatin	Rosuvastatin Buprenorphine may decrease the excretion rate of Rosuvastatin which could result in a higher serum level.
Vardenafil	Vardenafil The metabolism of Vardenafil can be decreased when combined with Buprenorphine.
Alfuzosin	Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Buprenorphine.
Aprepitant	Aprepitant The metabolism of Buprenorphine can be decreased when combined with Aprepitant.
Tegaserod	Tegaserod The metabolism of Buprenorphine can be decreased when combined with Tegaserod.
Tadalafil	Tadalafil The metabolism of Buprenorphine can be decreased when combined with Tadalafil.
Frovatriptan	Frovatriptan Frovatriptan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Progesterone	Progesterone The metabolism of Buprenorphine can be decreased when combined with Progesterone.
Apomorphine Injection	Apomorphine Injection Apomorphine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Infliximab Injection	Infliximab Injection The metabolism of Buprenorphine can be increased when combined with Infliximab.
Oxandrolone	Oxandrolone The metabolism of Buprenorphine can be decreased when combined with Oxandrolone.
Protriptyline	Protriptyline Protriptyline may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Rifaximin	Rifaximin The metabolism of Buprenorphine can be increased when combined with Rifaximin.
Duloxetine	Duloxetine Duloxetine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Norethindrone	Norethindrone The metabolism of Buprenorphine can be decreased when combined with Norethisterone.
Trospium	Trospium The risk or severity of adverse effects can be increased when Buprenorphine is combined with Trospium.
Bosentan	Bosentan The metabolism of Buprenorphine can be increased when combined with Bosentan.
Cinacalcet	Cinacalcet The metabolism of Buprenorphine can be decreased when combined with Cinacalcet.
Erlotinib	Erlotinib The metabolism of Buprenorphine can be decreased when combined with Erlotinib.
Eszopiclone	Eszopiclone Eszopiclone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Solifenacin	Solifenacin The risk or severity of adverse effects can be increased when Buprenorphine is combined with Solifenacin.
Voriconazole	Voriconazole The metabolism of Buprenorphine can be decreased when combined with Voriconazole.
Dextroamphetamine	Dextroamphetamine The risk or severity of serotonin syndrome and opioid toxicity can be increased when Buprenorphine is combined with Amphetamine.
Peginterferon Alfa-2b (PEG-Intron)	Peginterferon Alfa-2b (PEG-Intron) The metabolism of Buprenorphine can be increased when combined with Peginterferon alfa-2b.
Sodium Oxybate	Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Isocarboxazid	Isocarboxazid The risk or severity of serotonin syndrome and opioid toxicity can be increased when Buprenorphine is combined with Isocarboxazid.
Ramelteon	Ramelteon Ramelteon may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Darifenacin	Darifenacin The metabolism of Darifenacin can be decreased when combined with Buprenorphine.
Fentanyl	Fentanyl The metabolism of Fentanyl can be decreased when combined with Buprenorphine.
Pregabalin	Pregabalin Pregabalin may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Deferasirox	Deferasirox The metabolism of Buprenorphine can be decreased when combined with Deferasirox.
Tipranavir	Tipranavir The metabolism of Tipranavir can be decreased when combined with Buprenorphine.
Felbamate	Felbamate Felbamate may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Ranolazine	Ranolazine The serum concentration of Ranolazine can be increased when it is combined with Buprenorphine.
Abatacept Injection	Abatacept Injection The metabolism of Buprenorphine can be increased when combined with Abatacept.
Rasagiline	Rasagiline The risk or severity of serotonin syndrome and opioid toxicity can be increased when Buprenorphine is combined with Rasagiline.
Imatinib	Imatinib The metabolism of Buprenorphine can be decreased when combined with Imatinib.
Sitagliptin	Sitagliptin The metabolism of Sitagliptin can be decreased when combined with Buprenorphine.
Gefitinib	Gefitinib Buprenorphine may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Paliperidone	Paliperidone Paliperidone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Bortezomib	Bortezomib The metabolism of Buprenorphine can be decreased when combined with Bortezomib.
Clofarabine Injection	Clofarabine Injection Buprenorphine may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Lubiprostone	Lubiprostone The therapeutic efficacy of Lubiprostone can be decreased when used in combination with Buprenorphine.
Oxaliplatin Injection	Oxaliplatin Injection Buprenorphine may decrease the excretion rate of Oxaliplatin which could result in a higher serum level.
Primaquine	Primaquine The metabolism of Buprenorphine can be decreased when combined with Primaquine.
Darunavir	Darunavir The serum concentration of Darunavir can be increased when it is combined with Buprenorphine.
Dimenhydrinate	Dimenhydrinate Dimenhydrinate may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Lisdexamfetamine	Lisdexamfetamine Lisdexamfetamine may increase the analgesic activities of Buprenorphine.
Nabilone	Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Retapamulin	Retapamulin The metabolism of Retapamulin can be decreased when combined with Buprenorphine.
Sorafenib	Sorafenib The metabolism of Buprenorphine can be decreased when combined with Sorafenib.
Sunitinib	Sunitinib The metabolism of Sunitinib can be decreased when combined with Buprenorphine.
Dronabinol	Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Lapatinib	Lapatinib The metabolism of Buprenorphine can be decreased when combined with Lapatinib.
Levocetirizine	Levocetirizine Levocetirizine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Dasatinib	Dasatinib The metabolism of Dasatinib can be decreased when combined with Buprenorphine.
Mexiletine	Mexiletine The metabolism of Mexiletine can be decreased when combined with Buprenorphine.
Armodafinil	Armodafinil The metabolism of Buprenorphine can be increased when combined with Armodafinil.
Ivermectin	Ivermectin Buprenorphine may decrease the excretion rate of Ivermectin which could result in a higher serum level.
Paclitaxel (with polyoxyethylated castor oil) Injection	Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Buprenorphine.
Temsirolimus	Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Buprenorphine.
Nilotinib	Nilotinib The metabolism of Buprenorphine can be decreased when combined with Nilotinib.
Bexarotene	Bexarotene The metabolism of Buprenorphine can be decreased when combined with Bexarotene.
Budesonide	Budesonide The metabolism of Buprenorphine can be increased when combined with Budesonide.
Chloramphenicol Injection	Chloramphenicol Injection The metabolism of Buprenorphine can be decreased when combined with Chloramphenicol.
Desmopressin	Desmopressin The risk or severity of hyponatremia can be increased when Buprenorphine is combined with Desmopressin.
OnabotulinumtoxinA Injection	OnabotulinumtoxinA Injection Botulinum toxin type A may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
RimabotulinumtoxinB Injection	RimabotulinumtoxinB Injection Botulinum Toxin Type B may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Etravirine	Etravirine The metabolism of Etravirine can be decreased when combined with Buprenorphine.
Mitoxantrone Injection	Mitoxantrone Injection Buprenorphine may decrease the excretion rate of Mitoxantrone which could result in a higher serum level.
Desvenlafaxine	Desvenlafaxine Desvenlafaxine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Cevimeline	Cevimeline The metabolism of Cevimeline can be decreased when combined with Buprenorphine.
Nebivolol	Nebivolol The metabolism of Nebivolol can be decreased when combined with Buprenorphine.
Tretinoin	Tretinoin The metabolism of Buprenorphine can be decreased when combined with Tretinoin.
Flecainide	Flecainide The metabolism of Flecainide can be decreased when combined with Buprenorphine.
Certolizumab Injection	Certolizumab Injection The metabolism of Buprenorphine can be increased when combined with Certolizumab pegol.
Ixabepilone Injection	Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Buprenorphine.
Irinotecan Injection	Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Buprenorphine.
Praziquantel	Praziquantel The metabolism of Praziquantel can be decreased when combined with Buprenorphine.
Alvimopan	Alvimopan The risk or severity of adverse effects can be increased when Buprenorphine is combined with Alvimopan.
Methylnaltrexone Injection	Methylnaltrexone Injection Buprenorphine may increase the opioid antagonism activities of Methylnaltrexone.
Rufinamide	Rufinamide Rufinamide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Midazolam	Midazolam The serum concentration of Midazolam can be increased when it is combined with Buprenorphine.
Naltrexone Injection	Naltrexone Injection The therapeutic efficacy of Buprenorphine can be decreased when used in combination with Naltrexone.
Eltrombopag	Eltrombopag The metabolism of Buprenorphine can be decreased when combined with Eltrombopag.
Milnacipran	Milnacipran Milnacipran may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Dexlansoprazole	Dexlansoprazole The metabolism of Dexlansoprazole can be decreased when combined with Buprenorphine.
Sodium Phosphate	Sodium Phosphate The therapeutic efficacy of Sodium phosphate, monobasic can be decreased when used in combination with Buprenorphine.
Fesoterodine	Fesoterodine The risk or severity of adverse effects can be increased when Buprenorphine is combined with Fesoterodine.
Betaxolol	Betaxolol The metabolism of Betaxolol can be decreased when combined with Buprenorphine.
Iloperidone	Iloperidone Iloperidone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Prasugrel	Prasugrel The metabolism of Prasugrel can be decreased when combined with Buprenorphine.
Lacosamide	Lacosamide Lacosamide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Everolimus	Everolimus The metabolism of Everolimus can be decreased when combined with Buprenorphine.
Tolvaptan (low blood sodium)	Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be decreased when combined with Buprenorphine.
Dronedarone	Dronedarone The metabolism of Dronedarone can be decreased when combined with Buprenorphine.
AbobotulinumtoxinA Injection	AbobotulinumtoxinA Injection Botulinum toxin type A may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Pralatrexate Injection	Pralatrexate Injection Buprenorphine may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection	Palonosetron Injection Palonosetron may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Saxagliptin	Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Buprenorphine.
Romidepsin Injection	Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Buprenorphine.
Tapentadol	Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Topotecan	Topotecan Buprenorphine may decrease the excretion rate of Topotecan which could result in a higher serum level.
Golimumab Injection	Golimumab Injection The metabolism of Buprenorphine can be increased when combined with Golimumab.
Pazopanib	Pazopanib The metabolism of Pazopanib can be decreased when combined with Buprenorphine.
Asenapine	Asenapine Asenapine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Vigabatrin	Vigabatrin Vigabatrin may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Pitavastatin	Pitavastatin Buprenorphine may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Albendazole	Albendazole The metabolism of Albendazole can be decreased when combined with Buprenorphine.
Levonorgestrel	Levonorgestrel The metabolism of Buprenorphine can be decreased when combined with Levonorgestrel.
Oxymorphone	Oxymorphone Oxymorphone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Tocilizumab Injection	Tocilizumab Injection The metabolism of Buprenorphine can be increased when combined with Tocilizumab.
IncobotulinumtoxinA Injection	IncobotulinumtoxinA Injection Botulinum toxin type A may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Cabazitaxel Injection	Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Buprenorphine.
Lurasidone	Lurasidone Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Acetaminophen Injection	Acetaminophen Injection The metabolism of Acetaminophen can be decreased when combined with Buprenorphine.
Vilazodone	Vilazodone Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Busulfan Injection	Busulfan Injection The metabolism of Busulfan can be decreased when combined with Buprenorphine.
Roflumilast	Roflumilast The metabolism of Roflumilast can be decreased when combined with Buprenorphine.
Linagliptin	Linagliptin The metabolism of Linagliptin can be decreased when combined with Buprenorphine.
Rilpivirine	Rilpivirine The metabolism of Buprenorphine can be decreased when combined with Rilpivirine.
Telaprevir	Telaprevir The metabolism of Buprenorphine can be decreased when combined with Glecaprevir.
Cyclophosphamide Injection	Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Buprenorphine.
Abiraterone	Abiraterone The metabolism of Buprenorphine can be decreased when combined with Abiraterone.
Rivaroxaban	Rivaroxaban Buprenorphine may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ticagrelor	Ticagrelor Ticagrelor can cause a decrease in the absorption of Buprenorphine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Brentuximab Vedotin Injection	Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be decreased when combined with Buprenorphine.
Ruxolitinib	Ruxolitinib The metabolism of Ruxolitinib can be decreased when combined with Buprenorphine.
Vandetanib	Vandetanib The metabolism of Vandetanib can be decreased when combined with Buprenorphine.
Clobazam	Clobazam Clobazam may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Vemurafenib	Vemurafenib The metabolism of Vemurafenib can be decreased when combined with Buprenorphine.
Vismodegib	Vismodegib The metabolism of Buprenorphine can be decreased when combined with Vismodegib.
Ivacaftor	Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Buprenorphine.
Axitinib	Axitinib The metabolism of Axitinib can be decreased when combined with Buprenorphine.
Crizotinib	Crizotinib The metabolism of Buprenorphine can be decreased when combined with Crizotinib.
Cabergoline	Cabergoline Cabergoline may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Ambrisentan	Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Buprenorphine.
Ezogabine	Ezogabine Tiagabine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Enzalutamide	Enzalutamide The metabolism of Enzalutamide can be increased when combined with Buprenorphine.
Mirabegron	Mirabegron The metabolism of Mirabegron can be decreased when combined with Buprenorphine.
Regorafenib	Regorafenib The metabolism of Buprenorphine can be decreased when combined with Regorafenib.
Bosutinib	Bosutinib The metabolism of Buprenorphine can be decreased when combined with Bosutinib.
Linaclotide	Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Buprenorphine.
Teriflunomide	Teriflunomide Buprenorphine may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Cabozantinib (thyroid cancer)	Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Buprenorphine.
Tofacitinib	Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Buprenorphine.
Alogliptin	Alogliptin The metabolism of Alogliptin can be decreased when combined with Buprenorphine.
Ponatinib	Ponatinib The metabolism of Ponatinib can be decreased when combined with Buprenorphine.
Pomalidomide	Pomalidomide Pomalidomide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Ado-trastuzumab Emtansine Injection	Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Buprenorphine.
Apixaban	Apixaban Buprenorphine may decrease the excretion rate of Apixaban which could result in a higher serum level.
Canagliflozin	Canagliflozin The therapeutic efficacy of Canagliflozin can be decreased when used in combination with Buprenorphine.
Methazolamide	Methazolamide The therapeutic efficacy of Methazolamide can be decreased when used in combination with Buprenorphine.
Dabrafenib	Dabrafenib The metabolism of Buprenorphine can be decreased when combined with Dabrafenib.
Ospemifene	Ospemifene The metabolism of Ospemifene can be decreased when combined with Buprenorphine.
Trametinib	Trametinib The metabolism of Buprenorphine can be decreased when combined with Trametinib.
Dolutegravir	Dolutegravir Buprenorphine may decrease the excretion rate of Dolutegravir which could result in a higher serum level.
Afatinib	Afatinib Buprenorphine may decrease the excretion rate of Afatinib which could result in a higher serum level.
Levomilnacipran	Levomilnacipran Levomilnacipran may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Vortioxetine	Vortioxetine Vortioxetine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Perampanel	Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Ibrutinib	Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Buprenorphine.
Lomitapide	Lomitapide The metabolism of Lomitapide can be decreased when combined with Buprenorphine.
Ketorolac Injection	Ketorolac Injection The metabolism of Buprenorphine can be decreased when combined with Ketorolac.
Simeprevir	Simeprevir Buprenorphine may decrease the excretion rate of Simeprevir which could result in a higher serum level.
Sofosbuvir	Sofosbuvir Buprenorphine may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin	Dapagliflozin The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Buprenorphine.
Apremilast	Apremilast The metabolism of Buprenorphine can be increased when combined with Apremilast.
Ceritinib	Ceritinib The metabolism of Ceritinib can be decreased when combined with Buprenorphine.
Siltuximab Injection	Siltuximab Injection The metabolism of Buprenorphine can be increased when combined with Siltuximab.
Eslicarbazepine	Eslicarbazepine Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Idelalisib	Idelalisib The metabolism of Idelalisib can be decreased when combined with Buprenorphine.
Testosterone Injection	Testosterone Injection Buprenorphine may decrease the excretion rate of Testosterone which could result in a higher serum level.
Oritavancin Injection	Oritavancin Injection The metabolism of Buprenorphine can be decreased when combined with Oritavancin.
Vorapaxar	Vorapaxar The metabolism of Vorapaxar can be decreased when combined with Buprenorphine.
Hydrocodone	Hydrocodone The therapeutic efficacy of Hydrocodone can be decreased when used in combination with Buprenorphine.
Suvorexant	Suvorexant Buprenorphine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Olaparib	Olaparib The metabolism of Olaparib can be decreased when combined with Buprenorphine.
Methamphetamine	Methamphetamine Metamfetamine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Tasimelteon	Tasimelteon Tasimelteon may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Riociguat	Riociguat Buprenorphine may decrease the excretion rate of Riociguat which could result in a higher serum level.
Nintedanib	Nintedanib The metabolism of Nintedanib can be decreased when combined with Buprenorphine.
Secukinumab Injection	Secukinumab Injection The metabolism of Buprenorphine can be increased when combined with Secukinumab.
Risperidone Injection	Risperidone Injection Risperidone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Palbociclib	Palbociclib The metabolism of Palbociclib can be decreased when combined with Buprenorphine.
Lenvatinib	Lenvatinib Buprenorphine may decrease the excretion rate of Lenvatinib which could result in a higher serum level.
Naloxegol	Naloxegol Buprenorphine may increase the opioid antagonism activities of Naloxegol.
Panobinostat	Panobinostat The metabolism of Panobinostat can be decreased when combined with Buprenorphine.
Haloperidol Injection	Haloperidol Injection Haloperidol may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Amiloride	Amiloride The therapeutic efficacy of Amiloride can be decreased when used in combination with Buprenorphine.
Sonidegib	Sonidegib The metabolism of Sonidegib can be decreased when combined with Buprenorphine.
Flibanserin	Flibanserin Flibanserin may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Rolapitant	Rolapitant The metabolism of Buprenorphine can be decreased when combined with Rolapitant.
Daclatasvir	Daclatasvir The metabolism of Daclatasvir can be decreased when combined with Buprenorphine.
Brexpiprazole	Brexpiprazole Brexpiprazole may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Ziprasidone Injection	Ziprasidone Injection Ziprasidone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Cariprazine	Cariprazine Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Eluxadoline	Eluxadoline The risk or severity of constipation can be increased when Buprenorphine is combined with Eluxadoline.
Cobimetinib	Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Buprenorphine.
Trabectedin Injection	Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Buprenorphine.
Osimertinib	Osimertinib The metabolism of Osimertinib can be decreased when combined with Buprenorphine.
Alectinib	Alectinib The metabolism of Alectinib can be decreased when combined with Buprenorphine.
Ixazomib	Ixazomib The metabolism of Ixazomib can be decreased when combined with Buprenorphine.
Rifapentine	Rifapentine The metabolism of Buprenorphine can be increased when combined with Rifapentine.
Lesinurad	Lesinurad The metabolism of Lesinurad can be decreased when combined with Buprenorphine.
Dexamethasone Injection	Dexamethasone Injection The metabolism of Buprenorphine can be increased when combined with Dexamethasone.
Brivaracetam Injection	Brivaracetam Injection Brivaracetam may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Venetoclax	Venetoclax The metabolism of Venetoclax can be decreased when combined with Buprenorphine.
Cobicistat	Cobicistat The serum concentration of Buprenorphine can be increased when it is combined with Cobicistat.
Selexipag	Selexipag The metabolism of Selexipag can be decreased when combined with Buprenorphine.
Pimavanserin	Pimavanserin Pimavanserin may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Diphenhydramine Injection	Diphenhydramine Injection Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Furosemide Injection	Furosemide Injection The therapeutic efficacy of Furosemide can be decreased when used in combination with Buprenorphine.
Rucaparib	Rucaparib The metabolism of Buprenorphine can be decreased when combined with Rucaparib.
Ribociclib	Ribociclib The metabolism of Ribociclib can be decreased when combined with Buprenorphine.
Brigatinib	Brigatinib The metabolism of Brigatinib can be decreased when combined with Buprenorphine.
Doxepin (Insomnia)	Doxepin (Insomnia) Doxepin may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Plecanatide	Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Buprenorphine.
Deutetrabenazine	Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Buprenorphine.
Valbenazine	Valbenazine The metabolism of Valbenazine can be decreased when combined with Buprenorphine.
Deflazacort	Deflazacort The metabolism of Buprenorphine can be increased when combined with Deflazacort.
Safinamide	Safinamide The risk or severity of serotonin syndrome and opioid toxicity can be increased when Buprenorphine is combined with Safinamide.
Naldemedine	Naldemedine The therapeutic efficacy of Buprenorphine can be decreased when used in combination with Naldemedine.
Midostaurin	Midostaurin The metabolism of Buprenorphine can be decreased when combined with Midostaurin.
Neratinib	Neratinib The metabolism of Neratinib can be decreased when combined with Buprenorphine.
Enasidenib	Enasidenib The metabolism of Buprenorphine can be decreased when combined with Enasidenib.
Aprepitant/Fosaprepitant Injection	Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be decreased when combined with Buprenorphine.
Copanlisib Injection	Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Buprenorphine.
Delafloxacin	Delafloxacin Buprenorphine may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib	Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Buprenorphine.
Acalabrutinib	Acalabrutinib The metabolism of Buprenorphine can be decreased when combined with Acalabrutinib.
Letermovir	Letermovir The metabolism of Buprenorphine can be decreased when combined with Letermovir.
Tetrabenazine	Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Buprenorphine.
Ertugliflozin	Ertugliflozin The metabolism of Buprenorphine can be decreased when combined with Ertugliflozin.
Apalutamide	Apalutamide The metabolism of Buprenorphine can be decreased when combined with Apalutamide.
Fostamatinib	Fostamatinib The metabolism of Buprenorphine can be decreased when combined with Fostamatinib.
Avatrombopag	Avatrombopag The metabolism of Buprenorphine can be increased when combined with Avatrombopag.
Baricitinib	Baricitinib The metabolism of Baricitinib can be decreased when combined with Buprenorphine.
Lofexidine	Lofexidine The therapeutic efficacy of Buprenorphine can be increased when used in combination with Lofexidine.
Eliglustat	Eliglustat The metabolism of Eliglustat can be decreased when combined with Buprenorphine.
Encorafenib	Encorafenib The metabolism of Encorafenib can be decreased when combined with Buprenorphine.
Ivosidenib	Ivosidenib The metabolism of Ivosidenib can be decreased when combined with Buprenorphine.
Lusutrombopag	Lusutrombopag Buprenorphine may decrease the excretion rate of Lusutrombopag which could result in a higher serum level.
Elagolix	Elagolix The metabolism of Elagolix can be decreased when combined with Buprenorphine.
Doravirine	Doravirine The metabolism of Doravirine can be decreased when combined with Buprenorphine.
Tafenoquine	Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Buprenorphine.
Cannabidiol	Cannabidiol Cannabidiol may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Dacomitinib	Dacomitinib The metabolism of Buprenorphine can be decreased when combined with Dacomitinib.
Duvelisib	Duvelisib Buprenorphine may decrease the excretion rate of Duvelisib which could result in a higher serum level.
Stiripentol	Stiripentol Stiripentol may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Talazoparib	Talazoparib Buprenorphine may decrease the excretion rate of Talazoparib which could result in a higher serum level.
Gilteritinib	Gilteritinib The metabolism of Gilteritinib can be decreased when combined with Buprenorphine.
Glasdegib	Glasdegib Buprenorphine may decrease the excretion rate of Glasdegib which could result in a higher serum level.
Lorlatinib	Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Buprenorphine.
Paclitaxel (with albumin) Injection	Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Buprenorphine.
Rifamycin	Rifamycin The metabolism of Buprenorphine can be decreased when combined with Rifamycin.
Prucalopride	Prucalopride The metabolism of Prucalopride can be decreased when combined with Buprenorphine.
Magnesium Citrate	Magnesium Citrate The therapeutic efficacy of Magnesium citrate can be decreased when used in combination with Buprenorphine.
Emapalumab-lzsg Injection	Emapalumab-lzsg Injection The metabolism of Buprenorphine can be increased when combined with Emapalumab.
Siponimod	Siponimod The metabolism of Siponimod can be decreased when combined with Buprenorphine.
Erdafitinib	Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Buprenorphine.
Esomeprazole Injection	Esomeprazole Injection The metabolism of Esomeprazole can be decreased when combined with Buprenorphine.
Alpelisib	Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Buprenorphine.
Brexanolone Injection	Brexanolone Injection Brexanolone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Cladribine	Cladribine Buprenorphine may decrease the excretion rate of Cladribine which could result in a higher serum level.
Solriamfetol	Solriamfetol Solriamfetol may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Darolutamide	Darolutamide Buprenorphine may decrease the excretion rate of Darolutamide which could result in a higher serum level.
Triclabendazole	Triclabendazole The metabolism of Buprenorphine can be decreased when combined with Triclabendazole.
Entrectinib	Entrectinib The metabolism of Entrectinib can be decreased when combined with Buprenorphine.
Pexidartinib	Pexidartinib The metabolism of Buprenorphine can be decreased when combined with Pexidartinib.
Istradefylline	Istradefylline The metabolism of Istradefylline can be decreased when combined with Buprenorphine.
Pitolisant	Pitolisant The serum concentration of Buprenorphine can be decreased when it is combined with Pitolisant.
Fedratinib	Fedratinib The metabolism of Fedratinib can be decreased when combined with Buprenorphine.
Lefamulin	Lefamulin The metabolism of Lefamulin can be decreased when combined with Buprenorphine.
Phenytoin Injection	Phenytoin Injection Phenytoin may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Fosphenytoin Injection	Fosphenytoin Injection Fosphenytoin may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Zanubrutinib	Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Buprenorphine.
Voxelotor	Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Buprenorphine.
Avapritinib	Avapritinib The metabolism of Avapritinib can be decreased when combined with Buprenorphine.
Lumateperone	Lumateperone Lumateperone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Lasmiditan	Lasmiditan Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Ubrogepant	Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Buprenorphine.
Tazemetostat	Tazemetostat Buprenorphine may decrease the excretion rate of Tazemetostat which could result in a higher serum level.
Cenobamate	Cenobamate The serum concentration of Buprenorphine can be decreased when it is combined with Cenobamate.
Ozanimod	Ozanimod Buprenorphine may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Selumetinib	Selumetinib Buprenorphine may decrease the excretion rate of Selumetinib which could result in a higher serum level.
Rimegepant	Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Buprenorphine.
Tucatinib	Tucatinib The metabolism of Tucatinib can be decreased when combined with Buprenorphine.
Ripretinib	Ripretinib Buprenorphine may decrease the excretion rate of Ripretinib which could result in a higher serum level.
Selpercatinib	Selpercatinib The serum concentration of Buprenorphine can be increased when it is combined with Selpercatinib.
Lemborexant	Lemborexant Buprenorphine may increase the central nervous system depressant (CNS depressant) activities of Lemborexant.
Fenfluramine	Fenfluramine Fenfluramine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Pralsetinib	Pralsetinib Buprenorphine may decrease the excretion rate of Pralsetinib which could result in a higher serum level.
Opicapone	Opicapone The metabolism of Buprenorphine can be decreased when combined with Opicapone.
Satralizumab-mwge Injection	Satralizumab-mwge Injection The serum concentration of Buprenorphine can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives	Progestin-Only (drospirenone) Oral Contraceptives The therapeutic efficacy of Drospirenone can be decreased when used in combination with Buprenorphine.
Viloxazine	Viloxazine Viloxazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Theophylline	Theophylline The metabolism of Theophylline can be decreased when combined with Buprenorphine.
Indomethacin	Indomethacin The metabolism of Buprenorphine can be decreased when combined with Indomethacin.
Mefenamic Acid	Mefenamic Acid The metabolism of Buprenorphine can be decreased when combined with Mefenamic acid.
Naproxen	Naproxen The metabolism of Buprenorphine can be decreased when combined with Naproxen.
Trazodone	Trazodone Trazodone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Hydroxyurea	Hydroxyurea The metabolism of Buprenorphine can be decreased when combined with Hydroxyurea.
Floxuridine	Floxuridine The metabolism of Buprenorphine can be decreased when combined with Floxuridine.
Phenobarbital	Phenobarbital Phenobarbital may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Metaxalone	Metaxalone Metaxalone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Methotrexate Injection	Methotrexate Injection The metabolism of Methotrexate can be decreased when combined with Buprenorphine.
Levorphanol	Levorphanol Levorphanol may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Primidone	Primidone Primidone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Methsuximide	Methsuximide Methsuximide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Diethylpropion	Diethylpropion Diethylpropion may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Chlorpromazine	Chlorpromazine Chlorpromazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Diazepam	Diazepam Diazepam may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Oxazepam	Oxazepam Oxazepam may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Flurazepam	Flurazepam Flurazepam may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Clorazepate	Clorazepate Clorazepic acid may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Lorazepam	Lorazepam Lorazepam may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Amantadine	Amantadine The risk or severity of adverse effects can be increased when Amantadine is combined with Buprenorphine.
Codeine	Codeine Codeine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Meprobamate	Meprobamate Meprobamate may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Chlordiazepoxide	Chlordiazepoxide Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Bromocriptine	Bromocriptine Bromocriptine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Tranylcypromine	Tranylcypromine The risk or severity of serotonin syndrome and opioid toxicity can be increased when Buprenorphine is combined with Tranylcypromine.
Phenelzine	Phenelzine The risk or severity of serotonin syndrome and opioid toxicity can be increased when Buprenorphine is combined with Phenelzine.
Procarbazine	Procarbazine The risk or severity of serotonin syndrome and opioid toxicity can be increased when Buprenorphine is combined with Procarbazine.
Ergoloid Mesylates	Ergoloid Mesylates Ergoloid mesylate may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Minocycline	Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Prochlorperazine	Prochlorperazine Prochlorperazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Thioridazine	Thioridazine Thioridazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Trifluoperazine	Trifluoperazine Trifluoperazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Dapsone	Dapsone The metabolism of Dapsone can be decreased when combined with Buprenorphine.
Sulfadiazine	Sulfadiazine The metabolism of Buprenorphine can be decreased when combined with Sulfadiazine.
Oxycodone	Oxycodone Oxycodone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Methadone	Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Buprenorphine.
Oxybutynin	Oxybutynin The risk or severity of adverse effects can be increased when Oxybutynin is combined with Buprenorphine.
Benztropine	Benztropine The risk or severity of adverse effects can be increased when Buprenorphine is combined with Benzatropine.
Maprotiline	Maprotiline Maprotiline may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Ibuprofen	Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Buprenorphine.
Trihexyphenidyl	Trihexyphenidyl The risk or severity of adverse effects can be increased when Buprenorphine is combined with Trihexyphenidyl.
Orphenadrine	Orphenadrine Orphenadrine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Perphenazine	Perphenazine Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Fluphenazine	Fluphenazine Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Phentermine	Phentermine Phentermine may increase the analgesic activities of Buprenorphine.
Amoxapine	Amoxapine Amoxapine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Sulfasalazine	Sulfasalazine Buprenorphine may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Hydrocortisone	Hydrocortisone The metabolism of Buprenorphine can be increased when combined with Hydrocortisone.
Doxorubicin	Doxorubicin The metabolism of Doxorubicin can be decreased when combined with Buprenorphine.
Dactinomycin	Dactinomycin Buprenorphine may decrease the excretion rate of Dactinomycin which could result in a higher serum level.
Carbamazepine	Carbamazepine Carbamazepine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Molindone	Molindone Molindone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Clonidine	Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Buprenorphine.
Prazosin	Prazosin Buprenorphine may decrease the excretion rate of Prazosin which could result in a higher serum level.
Cimetidine	Cimetidine The metabolism of Cimetidine can be decreased when combined with Buprenorphine.
Warfarin	Warfarin The serum concentration of Warfarin can be increased when it is combined with Buprenorphine.
Clonazepam	Clonazepam Clonazepam may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Loperamide	Loperamide The metabolism of Buprenorphine can be decreased when combined with Loperamide.
Promethazine	Promethazine Promethazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Daunorubicin	Daunorubicin Buprenorphine may decrease the excretion rate of Daunorubicin which could result in a higher serum level.
Nitrofurantoin	Nitrofurantoin Buprenorphine may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Griseofulvin	Griseofulvin The metabolism of Buprenorphine can be increased when combined with Griseofulvin.
Loxapine	Loxapine Loxapine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Chloroquine	Chloroquine The metabolism of Buprenorphine can be decreased when combined with Chloroquine.
Quinine	Quinine Quinine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Ethosuximide	Ethosuximide Ethosuximide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Triamterene	Triamterene The therapeutic efficacy of Triamterene can be decreased when used in combination with Buprenorphine.
Lactulose	Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Buprenorphine.
Sulfinpyrazone	Sulfinpyrazone The metabolism of Buprenorphine can be decreased when combined with Sulfinpyrazone.
Chlorothiazide	Chlorothiazide The therapeutic efficacy of Chlorothiazide can be decreased when used in combination with Buprenorphine.
Chlorthalidone	Chlorthalidone The therapeutic efficacy of Chlorthalidone can be decreased when used in combination with Buprenorphine.
Metolazone	Metolazone The therapeutic efficacy of Metolazone can be decreased when used in combination with Buprenorphine.
Isosorbide	Isosorbide The therapeutic efficacy of Isosorbide can be decreased when used in combination with Buprenorphine.
Clindamycin Injection	Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Buprenorphine.
Secobarbital	Secobarbital Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Desipramine	Desipramine Desipramine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Amitriptyline	Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Buprenorphine.
Imipramine	Imipramine Imipramine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Probenecid	Probenecid The metabolism of Buprenorphine can be decreased when combined with Probenecid.
Quinidine	Quinidine The risk or severity of adverse effects can be increased when Buprenorphine is combined with Quinidine.
Procainamide	Procainamide The metabolism of Procainamide can be decreased when combined with Buprenorphine.
Isoniazid	Isoniazid The metabolism of Buprenorphine can be decreased when combined with Isoniazid.
Rifampin	Rifampin The metabolism of Buprenorphine can be increased when combined with Rifampicin.
Disopyramide	Disopyramide The risk or severity of adverse effects can be increased when Buprenorphine is combined with Disopyramide.
Valproic Acid	Valproic Acid Valproic acid may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Tamoxifen	Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Buprenorphine.
Butabarbital	Butabarbital Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Levothyroxine	Levothyroxine The metabolism of Buprenorphine can be decreased when combined with Levothyroxine.
Methimazole	Methimazole The metabolism of Buprenorphine can be decreased when combined with Methimazole.
Chlorpropamide	Chlorpropamide The metabolism of Buprenorphine can be decreased when combined with Chlorpropamide.
Tolbutamide	Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Buprenorphine.
Tolazamide	Tolazamide The metabolism of Buprenorphine can be decreased when combined with Tolazamide.
Dextromethorphan	Dextromethorphan Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Cyclobenzaprine	Cyclobenzaprine Cyclobenzaprine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Niacin	Niacin The metabolism of Buprenorphine can be decreased when combined with Niacin.
Baclofen	Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine	Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Cyproheptadine	Cyproheptadine Cyproheptadine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Clemastine	Clemastine Clemastine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Chlorpheniramine	Chlorpheniramine Chlorpheniramine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Brompheniramine	Brompheniramine Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Meclizine	Meclizine Meclizine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Methyclothiazide	Methyclothiazide The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Buprenorphine.
Hydrochlorothiazide	Hydrochlorothiazide The therapeutic efficacy of Hydrochlorothiazide can be decreased when used in combination with Buprenorphine.
Dantrolene	Dantrolene Dantrolene may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Chlorzoxazone	Chlorzoxazone Chlorzoxazone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Carisoprodol	Carisoprodol Carisoprodol may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Methocarbamol	Methocarbamol Methocarbamol may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Folic Acid	Folic Acid Buprenorphine may decrease the excretion rate of Folic acid which could result in a higher serum level.
Disulfiram	Disulfiram The metabolism of Buprenorphine can be decreased when combined with Disulfiram.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Buprenorphine.
Pseudoephedrine	Pseudoephedrine Pseudoephedrine may increase the analgesic activities of Buprenorphine.
Nortriptyline	Nortriptyline Nortriptyline may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Spironolactone	Spironolactone The metabolism of Buprenorphine can be decreased when combined with Spironolactone.
Nadolol	Nadolol The metabolism of Nadolol can be decreased when combined with Buprenorphine.
Butorphanol Injection	Butorphanol Injection Butorphanol may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Nalbuphine Injection	Nalbuphine Injection Nalbuphine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Allopurinol	Allopurinol Buprenorphine may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Trimethobenzamide	Trimethobenzamide Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Flavoxate	Flavoxate The risk or severity of adverse effects can be increased when Buprenorphine is combined with Flavoxate.
Fluorouracil Injection	Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Buprenorphine.
Colchicine	Colchicine The metabolism of Colchicine can be decreased when combined with Buprenorphine.
Cephalexin	Cephalexin The metabolism of Buprenorphine can be decreased when combined with Cephalexin.
Acetazolamide	Acetazolamide Acetazolamide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Ketoconazole	Ketoconazole The metabolism of Buprenorphine can be decreased when combined with Ketoconazole.
Pyrantel	Pyrantel Pyrantel may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Thiotepa Injection	Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Buprenorphine.
Vincristine Injection	Vincristine Injection The metabolism of Vincristine can be decreased when combined with Buprenorphine.
Vinblastine	Vinblastine The metabolism of Buprenorphine can be decreased when combined with Vinblastine.
Ethacrynic Acid	Ethacrynic Acid The therapeutic efficacy of Etacrynic acid can be decreased when used in combination with Buprenorphine.
Metoprolol	Metoprolol The metabolism of Metoprolol can be decreased when combined with Buprenorphine.
Hydroxyzine	Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Thiothixene	Thiothixene Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Aspirin	Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Buprenorphine.
Alprazolam	Alprazolam The metabolism of Alprazolam can be decreased when combined with Buprenorphine.
Temazepam	Temazepam Temazepam may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Triazolam	Triazolam Triazolam may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Dicyclomine	Dicyclomine The risk or severity of adverse effects can be increased when Buprenorphine is combined with Dicyclomine.
Hyoscyamine	Hyoscyamine The risk or severity of adverse effects can be increased when Buprenorphine is combined with Hyoscyamine.
Propantheline	Propantheline The risk or severity of adverse effects can be increased when Buprenorphine is combined with Propantheline.
Trimethoprim	Trimethoprim The metabolism of Buprenorphine can be decreased when combined with Trimethoprim.
Diltiazem	Diltiazem The metabolism of Buprenorphine can be decreased when combined with Diltiazem.
Nifedipine	Nifedipine The metabolism of Buprenorphine can be decreased when combined with Nifedipine.
Timolol	Timolol The metabolism of Timolol can be decreased when combined with Buprenorphine.
Verapamil	Verapamil The metabolism of Buprenorphine can be decreased when combined with Verapamil.
Atenolol	Atenolol The metabolism of Atenolol can be decreased when combined with Buprenorphine.
Pindolol	Pindolol Pindolol may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Cisplatin Injection	Cisplatin Injection The metabolism of Buprenorphine can be decreased when combined with Cisplatin.
Diflunisal	Diflunisal The metabolism of Buprenorphine can be decreased when combined with Diflunisal.
Piroxicam	Piroxicam The metabolism of Buprenorphine can be decreased when combined with Piroxicam.
Bumetanide	Bumetanide The therapeutic efficacy of Bumetanide can be decreased when used in combination with Buprenorphine.
Etoposide	Etoposide The metabolism of Etoposide can be decreased when combined with Buprenorphine.
Glyburide	Glyburide Buprenorphine may decrease the excretion rate of Glyburide which could result in a higher serum level.
Glipizide	Glipizide The metabolism of Glipizide can be decreased when combined with Buprenorphine.
Indapamide	Indapamide The therapeutic efficacy of Indapamide can be decreased when used in combination with Buprenorphine.
Pentamidine Injection	Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Buprenorphine.
Labetalol	Labetalol The metabolism of Buprenorphine can be decreased when combined with Labetalol.
Gemfibrozil	Gemfibrozil The metabolism of Buprenorphine can be decreased when combined with Gemfibrozil.
Ketoprofen	Ketoprofen The metabolism of Buprenorphine can be decreased when combined with Ketoprofen.
Pimozide	Pimozide Pimozide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Flurbiprofen	Flurbiprofen The metabolism of Buprenorphine can be decreased when combined with Flurbiprofen.
Amiodarone	Amiodarone The metabolism of Amiodarone can be decreased when combined with Buprenorphine.
Buspirone	Buspirone The risk or severity of serotonin syndrome can be increased when Buspirone is combined with Buprenorphine.
Lovastatin	Lovastatin The metabolism of Lovastatin can be decreased when combined with Buprenorphine.
Ciprofloxacin	Ciprofloxacin The metabolism of Buprenorphine can be decreased when combined with Ciprofloxacin.
Diclofenac	Diclofenac The metabolism of Buprenorphine can be decreased when combined with Diclofenac.
Fluoxetine	Fluoxetine Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Clozapine	Clozapine Clozapine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Estazolam	Estazolam Estazolam may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Idarubicin	Idarubicin The metabolism of Idarubicin can be decreased when combined with Buprenorphine.
Clarithromycin	Clarithromycin The metabolism of Buprenorphine can be decreased when combined with Clarithromycin.
Etodolac	Etodolac The metabolism of Buprenorphine can be decreased when combined with Etodolac.
Felodipine	Felodipine The metabolism of Buprenorphine can be decreased when combined with Felodipine.
Nabumetone	Nabumetone The metabolism of Buprenorphine can be decreased when combined with Nabumetone.
Pravastatin	Pravastatin Buprenorphine may decrease the excretion rate of Pravastatin which could result in a higher serum level.
Simvastatin	Simvastatin The metabolism of Buprenorphine can be decreased when combined with Simvastatin.
Teniposide Injection	Teniposide Injection The metabolism of Teniposide can be decreased when combined with Buprenorphine.
Itraconazole	Itraconazole The metabolism of Buprenorphine can be decreased when combined with Itraconazole.
Atovaquone	Atovaquone The metabolism of Buprenorphine can be decreased when combined with Atovaquone.
Rifabutin	Rifabutin The metabolism of Buprenorphine can be increased when combined with Rifabutin.
Sotalol	Sotalol The metabolism of Sotalol can be decreased when combined with Buprenorphine.
Zolpidem	Zolpidem Zolpidem may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxazosin	Doxazosin The metabolism of Doxazosin can be decreased when combined with Buprenorphine.
Omeprazole	Omeprazole The metabolism of Buprenorphine can be decreased when combined with Omeprazole.
Cisapride	Cisapride Cisapride may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Gabapentin	Gabapentin Gabapentin may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Fluvastatin	Fluvastatin The metabolism of Buprenorphine can be decreased when combined with Fluvastatin.
Venlafaxine	Venlafaxine Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Famciclovir	Famciclovir The metabolism of Buprenorphine can be decreased when combined with Famciclovir.
Fluvoxamine	Fluvoxamine Fluvoxamine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Nefazodone	Nefazodone Nefazodone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Lamotrigine	Lamotrigine Lamotrigine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Losartan	Losartan The metabolism of Buprenorphine can be decreased when combined with Losartan.
Tramadol	Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Buprenorphine.
Vinorelbine Injection	Vinorelbine Injection The metabolism of Buprenorphine can be decreased when combined with Vinorelbine.
Lansoprazole	Lansoprazole The metabolism of Buprenorphine can be decreased when combined with Lansoprazole.
Ifosfamide Injection	Ifosfamide Injection The metabolism of Buprenorphine can be decreased when combined with Ifosfamide.
Nicardipine	Nicardipine The metabolism of Buprenorphine can be decreased when combined with Nicardipine.
Bupropion	Bupropion Bupropion may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Ticlopidine	Ticlopidine The metabolism of Buprenorphine can be decreased when combined with Ticlopidine.
Saquinavir	Saquinavir The metabolism of Buprenorphine can be decreased when combined with Saquinavir.
Nisoldipine	Nisoldipine The metabolism of Buprenorphine can be decreased when combined with Nisoldipine.
Lamivudine	Lamivudine Buprenorphine may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole	Riluzole Riluzole may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Glimepiride	Glimepiride The metabolism of Buprenorphine can be decreased when combined with Glimepiride.
Anastrozole	Anastrozole The metabolism of Buprenorphine can be decreased when combined with Anastrozole.
Indinavir	Indinavir The metabolism of Buprenorphine can be decreased when combined with Indinavir.
Ritonavir	Ritonavir The serum concentration of Buprenorphine can be increased when it is combined with Ritonavir.
Docetaxel Injection	Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Buprenorphine.
Clomipramine	Clomipramine Clomipramine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Zafirlukast	Zafirlukast The metabolism of Buprenorphine can be decreased when combined with Zafirlukast.
Mirtazapine	Mirtazapine Buprenorphine may increase the serotonergic activities of Mirtazapine.
Topiramate	Topiramate Topiramate may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Zileuton	Zileuton The metabolism of Buprenorphine can be decreased when combined with Zileuton.
Valsartan	Valsartan The metabolism of Buprenorphine can be decreased when combined with Valsartan.
Pramipexole	Pramipexole Buprenorphine may increase the sedative activities of Pramipexole.
Donepezil	Donepezil Donepezil may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Nelfinavir	Nelfinavir The metabolism of Nelfinavir can be decreased when combined with Buprenorphine.
Azithromycin	Azithromycin The metabolism of Azithromycin can be decreased when combined with Buprenorphine.
Loratadine	Loratadine The metabolism of Buprenorphine can be decreased when combined with Loratadine.
Carvedilol	Carvedilol The metabolism of Carvedilol can be decreased when combined with Buprenorphine.
Nilutamide	Nilutamide The metabolism of Buprenorphine can be decreased when combined with Nilutamide.
Flutamide	Flutamide The metabolism of Buprenorphine can be decreased when combined with Flutamide.
Selegiline	Selegiline The risk or severity of serotonin syndrome and opioid toxicity can be increased when Buprenorphine is combined with Selegiline.
Bicalutamide	Bicalutamide The metabolism of Buprenorphine can be decreased when combined with Bicalutamide.
Sertraline	Sertraline Sertraline may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Propafenone	Propafenone The metabolism of Buprenorphine can be decreased when combined with Propafenone.
Raloxifene	Raloxifene Buprenorphine may decrease the excretion rate of Raloxifene which could result in a higher serum level.
Irbesartan	Irbesartan The metabolism of Buprenorphine can be decreased when combined with Irbesartan.
Tamsulosin	Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Buprenorphine.
Ropinirole	Ropinirole Ropinirole may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Finasteride	Finasteride The metabolism of Finasteride can be decreased when combined with Buprenorphine.
Quetiapine	Quetiapine Quetiapine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Cetirizine	Cetirizine Cetirizine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Paroxetine	Paroxetine Paroxetine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Tolcapone	Tolcapone Tolcapone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Citalopram	Citalopram Citalopram may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Capecitabine	Capecitabine The metabolism of Buprenorphine can be decreased when combined with Capecitabine.
Efavirenz	Efavirenz Efavirenz may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Sildenafil	Sildenafil The metabolism of Buprenorphine can be decreased when combined with Sildenafil.
Pioglitazone	Pioglitazone The metabolism of Buprenorphine can be decreased when combined with Pioglitazone.
Celecoxib	Celecoxib The metabolism of Celecoxib can be decreased when combined with Buprenorphine.
Rosiglitazone	Rosiglitazone The metabolism of Buprenorphine can be decreased when combined with Rosiglitazone.
Tolterodine	Tolterodine The risk or severity of adverse effects can be increased when Buprenorphine is combined with Tolterodine.
Thalidomide	Thalidomide Buprenorphine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Nateglinide	Nateglinide The metabolism of Buprenorphine can be decreased when combined with Nateglinide.
Galantamine	Galantamine The metabolism of Galantamine can be decreased when combined with Buprenorphine.
Levetiracetam	Levetiracetam Levetiracetam may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Rabeprazole	Rabeprazole The metabolism of Buprenorphine can be decreased when combined with Rabeprazole.
Terbinafine	Terbinafine The metabolism of Buprenorphine can be decreased when combined with Terbinafine.