Copanlisib Injection
Generic name: Pronounced as (koe" pan lis' ib)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 04/15/2020
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Why is this medication prescribed?
Copanlisib injection is used to treat people with follicular lymphoma (FL; a slow-growing blood cancer) that has returned after being treated 2 or more times with other medications. Copanlisib injection is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
How should this medicine be used?
Copanlisib injection comes as a powder to be mixed with liquid and given through a needle or catheter placed into a vein. It is usually injected slowly over a period of 60 minutes on days 1,8, and 15 of a 28-day treatment cycle.
Copanlisib injection may cause high blood pressure for up to 8 hours after the infusion. Your doctor will check your blood pressure before you receive the infusion and for several hours after the infusion is completed. If you experience any of the following symptoms after you receive the medication tell your doctor immediately: dizziness, feeling faint, headache, or pounding heartbeat.
Your doctor may reduce your dose, delay or stop your treatment with copanlisib injection, or treat you with additional medications depending on your response to the medication and any side effects that you experience. Talk to your doctor about how you are feeling during your treatment.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before receiving copanlisib injection,
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tell your doctor and pharmacist if you are allergic to copanlisib, any other medications, or any of the ingredients in copanlisib injection. Ask your pharmacist for a list of the ingredients.
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tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements and herbal products you are taking or plan to take. Be sure to mention any of the following: boceprevir (Victrelis); carbamazepine (Carbatrol, Equetro, Tegretol, others), clarithromycin (Biaxin, in Prevpac), cobicistat (Tybost, in Evotaz, Genvoya, Prezcobix, Stribild), conivaptan (Vaprisol), diltiazem (Cardizem, Cartia XT, Diltzac, others), efavirenz (Sustiva), enzalutamide (Xtandi), idelalisib (Zydelig), indinavir (Crixivan) with ritonavir; itraconazole (Sporonox, Onmel), and ketoconazole, lopinavir with ritonavir (in Kaletra); mitotane (Lysodren), nefazodone, nelfinavir (Viracept), nevirapine (Viramune), paritaprevir, ritonavir, ombitasvir, and/or dasabuvir (Viekira Pak); phenobarbital, phenytoin (Dilantin, Phenytek), posaconazole (Noxafil), rifabutin (Mycobutin), rifampin (Rifadine, in Rifamate, Rifater), ritonavir (Norvir, in Kaletra, Technivie, Viekira Pak), saquinavir (Invirase), and tipranavir (Aptivus) with ritonavir; and voriconazole (Vfend). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with copanlisib injection, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
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tell your doctor what herbal products you are taking, especially St. John's wort.
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tell your doctor if you have an infection or if you have or have ever had high blood sugar, diabetes, lung or breathing problems, high blood pressure, or liver disease.
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tell your doctor if you are pregnant, plan to become pregnant, or plan to father a child. You should not become pregnant while you are receiving copanlisib injection. You will need to have a negative pregnancy test before you begin receiving this medication. Use effective birth control during your treatment with copanlisib injection and for 1 month after your final dose. If you are a male and your partner can become pregnant, you should use effective birth control during your treatment and for 1 month after your final dose. If you or your partner become pregnant while receiving copanlisib, call your doctor.
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tell your doctor if you are breastfeeding. You should not breastfeed while you are receiving copanlisib injection, and for 1 month after your final dose.
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you should know that this medication may decrease fertility in men and women. Talk to your doctor about the risks of receiving copanlisib injection.
What special dietary instructions should I follow?
Do not drink grapefruit juice while receiving this medication.
Unless your doctor tells you otherwise, continue your normal diet.
What side effects can this medication cause?
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Copanlisib injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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diarrhea
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nausea
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vomiting
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mouth sores, ulcers, or pain
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burning, prickling, tingling, or numb feeling on the skin
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pain upon touch
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swelling of nose, throat, or mouth
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lack of strength or energy
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Some side effects can be serious. If you experience any of these symptoms call your doctor immediately:
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unusual bleeding or bruising
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new or worsening cough, shortness of breath, or difficulty breathing
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rash; or red, itching, peeling or swelling skin
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fever, sore throat, chills, or other signs of infection
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feeling very hungry or thirsty, headache, or frequent urination
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Copanlisib injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to copanlisib injection.
Ask your pharmacist any questions you have about copanlisib injection.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Delavirdine | Delavirdine The metabolism of Copanlisib can be decreased when combined with Delavirdine. |
Nevirapine | Nevirapine The metabolism of Copanlisib can be decreased when combined with Nevirapine. |
Atorvastatin | Atorvastatin The metabolism of Copanlisib can be decreased when combined with Atorvastatin. |
Cilostazol | Cilostazol The metabolism of Copanlisib can be decreased when combined with Cilostazol. |
Clopidogrel | Clopidogrel The metabolism of Copanlisib can be decreased when combined with Clopidogrel. |
Erythromycin and Sulfisoxazole | Erythromycin and Sulfisoxazole The serum concentration of Copanlisib can be increased when it is combined with Erythromycin. |
Fenofibrate | Fenofibrate The metabolism of Copanlisib can be decreased when combined with Fenofibrate. |
Methylergonovine | Methylergonovine The metabolism of Copanlisib can be decreased when combined with Methylergometrine. |
Paregoric | Paregoric The serum concentration of Copanlisib can be increased when it is combined with Morphine. |
Reserpine | Reserpine The serum concentration of Copanlisib can be increased when it is combined with Reserpine. |
Tacrolimus | Tacrolimus The metabolism of Tacrolimus can be decreased when combined with Copanlisib. |
Triamcinolone | Triamcinolone The metabolism of Copanlisib can be increased when combined with Triamcinolone. |
Doxycycline Injection | Doxycycline Injection The metabolism of Copanlisib can be decreased when combined with Doxycycline. |
Fluconazole Injection | Fluconazole Injection The serum concentration of Copanlisib can be increased when it is combined with Fluconazole. |
Meperidine Injection | Meperidine Injection The metabolism of Copanlisib can be increased when combined with Meperidine. |
Methylprednisolone Injection | Methylprednisolone Injection The metabolism of Copanlisib can be increased when combined with Methylprednisolone. |
Metronidazole Injection | Metronidazole Injection The metabolism of Copanlisib can be decreased when combined with Metronidazole. |
Morphine Injection | Morphine Injection The serum concentration of Copanlisib can be increased when it is combined with Morphine. |
Cyclosporine | Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Copanlisib. |
Ondansetron | Ondansetron The metabolism of Copanlisib can be decreased when combined with Ondansetron. |
Orlistat | Orlistat The metabolism of Copanlisib can be increased when combined with Orlistat. |
Oxcarbazepine | Oxcarbazepine The metabolism of Copanlisib can be increased when combined with Oxcarbazepine. |
Pantoprazole | Pantoprazole Pantoprazole may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Telmisartan | Telmisartan Telmisartan may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Zaleplon | Zaleplon The metabolism of Copanlisib can be decreased when combined with Zaleplon. |
Anakinra | Anakinra The metabolism of Copanlisib can be increased when combined with Anakinra. |
Trimipramine | Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Copanlisib. |
Etanercept Injection | Etanercept Injection The metabolism of Copanlisib can be increased when combined with Etanercept. |
Modafinil | Modafinil The metabolism of Copanlisib can be increased when combined with Modafinil. |
Tenofovir | Tenofovir The metabolism of Tenofovir can be decreased when combined with Copanlisib. |
Sirolimus | Sirolimus The metabolism of Sirolimus can be decreased when combined with Copanlisib. |
Dutasteride | Dutasteride The metabolism of Copanlisib can be decreased when combined with Dutasteride. |
Epinephrine Injection | Epinephrine Injection The metabolism of Copanlisib can be decreased when combined with Epinephrine. |
Eplerenone | Eplerenone The metabolism of Copanlisib can be decreased when combined with Eplerenone. |
Zonisamide | Zonisamide The serum concentration of Copanlisib can be increased when it is combined with Zonisamide. |
Adalimumab Injection | Adalimumab Injection The metabolism of Copanlisib can be increased when combined with Adalimumab. |
Aripiprazole | Aripiprazole The metabolism of Copanlisib can be decreased when combined with Aripiprazole. |
Atazanavir | Atazanavir The metabolism of Copanlisib can be decreased when combined with Atazanavir. |
Mefloquine | Mefloquine The metabolism of Copanlisib can be decreased when combined with Mefloquine. |
Rosuvastatin | Rosuvastatin The metabolism of Copanlisib can be decreased when combined with Rosuvastatin. |
Vardenafil | Vardenafil The serum concentration of Vardenafil can be increased when it is combined with Copanlisib. |
Aprepitant | Aprepitant The metabolism of Copanlisib can be decreased when combined with Aprepitant. |
Tegaserod | Tegaserod The serum concentration of Copanlisib can be increased when it is combined with Tegaserod. |
Tadalafil | Tadalafil The metabolism of Copanlisib can be decreased when combined with Tadalafil. |
Progesterone | Progesterone The metabolism of Copanlisib can be increased when combined with Progesterone. |
Apomorphine Injection | Apomorphine Injection The metabolism of Copanlisib can be decreased when combined with Apomorphine. |
Darbepoetin Alfa Injection | Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Copanlisib. |
Infliximab Injection | Infliximab Injection The metabolism of Copanlisib can be increased when combined with Infliximab. |
Rifaximin | Rifaximin The metabolism of Copanlisib can be increased when combined with Rifaximin. |
Duloxetine | Duloxetine The metabolism of Copanlisib can be decreased when combined with Duloxetine. |
Norethindrone | Norethindrone The metabolism of Copanlisib can be decreased when combined with Norethisterone. |
Bosentan | Bosentan The metabolism of Copanlisib can be increased when combined with Bosentan. |
Erlotinib | Erlotinib The metabolism of Copanlisib can be decreased when combined with Erlotinib. |
Ganciclovir | Ganciclovir The excretion of Ganciclovir can be decreased when combined with Copanlisib. |
Voriconazole | Voriconazole The metabolism of Copanlisib can be decreased when combined with Voriconazole. |
Fentanyl | Fentanyl The metabolism of Copanlisib can be decreased when combined with Fentanyl. |
Deferasirox | Deferasirox The metabolism of Copanlisib can be increased when combined with Deferasirox. |
Tipranavir | Tipranavir The serum concentration of Tipranavir can be increased when it is combined with Copanlisib. |
Felbamate | Felbamate The metabolism of Copanlisib can be increased when combined with Felbamate. |
Ranolazine | Ranolazine The serum concentration of Copanlisib can be increased when it is combined with Ranolazine. |
Abatacept Injection | Abatacept Injection The metabolism of Copanlisib can be increased when combined with Abatacept. |
Imatinib | Imatinib The metabolism of Copanlisib can be decreased when combined with Imatinib. |
Sitagliptin | Sitagliptin The serum concentration of Copanlisib can be increased when it is combined with Sitagliptin. |
Gefitinib | Gefitinib The metabolism of Copanlisib can be decreased when combined with Gefitinib. |
Paliperidone | Paliperidone The serum concentration of Copanlisib can be increased when it is combined with Paliperidone. |
Bortezomib | Bortezomib The serum concentration of Copanlisib can be increased when it is combined with Bortezomib. |
Posaconazole | Posaconazole The metabolism of Copanlisib can be decreased when combined with Posaconazole. |
Primaquine | Primaquine The metabolism of Copanlisib can be decreased when combined with Primaquine. |
Darunavir | Darunavir The serum concentration of Copanlisib can be increased when it is combined with Darunavir. |
Sorafenib | Sorafenib The serum concentration of Copanlisib can be increased when it is combined with Sorafenib. |
Sunitinib | Sunitinib The metabolism of Copanlisib can be decreased when combined with Sunitinib. |
Dronabinol | Dronabinol Dronabinol may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Lapatinib | Lapatinib The serum concentration of Copanlisib can be increased when it is combined with Lapatinib. |
Dasatinib | Dasatinib The metabolism of Dasatinib can be decreased when combined with Copanlisib. |
Armodafinil | Armodafinil The metabolism of Copanlisib can be increased when combined with Armodafinil. |
Ivermectin | Ivermectin The metabolism of Copanlisib can be increased when combined with Ivermectin. |
Temsirolimus | Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Copanlisib. |
Nilotinib | Nilotinib The serum concentration of Copanlisib can be increased when it is combined with Nilotinib. |
Toremifene | Toremifene The serum concentration of Copanlisib can be increased when it is combined with Toremifene. |
Bexarotene | Bexarotene The metabolism of Copanlisib can be increased when combined with Bexarotene. |
Budesonide | Budesonide The metabolism of Copanlisib can be increased when combined with Budesonide. |
Chloramphenicol Injection | Chloramphenicol Injection The metabolism of Copanlisib can be decreased when combined with Chloramphenicol. |
Etravirine | Etravirine The metabolism of Copanlisib can be increased when combined with Etravirine. |
Mitoxantrone Injection | Mitoxantrone Injection The metabolism of Copanlisib can be decreased when combined with Mitoxantrone. |
Desvenlafaxine | Desvenlafaxine The metabolism of Copanlisib can be decreased when combined with Desvenlafaxine. |
Tretinoin | Tretinoin The metabolism of Copanlisib can be decreased when combined with Tretinoin. |
Bendamustine Injection | Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Copanlisib. |
Pilocarpine | Pilocarpine The metabolism of Copanlisib can be decreased when combined with Pilocarpine. |
Certolizumab Injection | Certolizumab Injection The metabolism of Copanlisib can be increased when combined with Certolizumab pegol. |
Irinotecan Injection | Irinotecan Injection The metabolism of Copanlisib can be decreased when combined with Irinotecan. |
Praziquantel | Praziquantel The metabolism of Copanlisib can be decreased when combined with Praziquantel. |
Mitotane | Mitotane The metabolism of Copanlisib can be increased when combined with Mitotane. |
Rufinamide | Rufinamide The metabolism of Copanlisib can be increased when combined with Rufinamide. |
Silodosin | Silodosin The serum concentration of Copanlisib can be increased when it is combined with Silodosin. |
Midazolam | Midazolam The metabolism of Copanlisib can be decreased when combined with Midazolam. |
Eltrombopag | Eltrombopag Eltrombopag may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Milnacipran | Milnacipran The metabolism of Copanlisib can be decreased when combined with Milnacipran. |
Iloperidone | Iloperidone The metabolism of Copanlisib can be decreased when combined with Iloperidone. |
Lacosamide | Lacosamide The metabolism of Copanlisib can be decreased when combined with Lacosamide. |
Everolimus | Everolimus The serum concentration of Copanlisib can be increased when it is combined with Everolimus. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) The serum concentration of Tolvaptan can be increased when it is combined with Copanlisib. |
Dronedarone | Dronedarone The serum concentration of Dronedarone can be increased when it is combined with Copanlisib. |
Saxagliptin | Saxagliptin The metabolism of Copanlisib can be decreased when combined with Saxagliptin. |
Romidepsin Injection | Romidepsin Injection The metabolism of Copanlisib can be decreased when combined with Romidepsin. |
Topotecan | Topotecan The metabolism of Topotecan can be increased when combined with Copanlisib. |
Golimumab Injection | Golimumab Injection The metabolism of Copanlisib can be increased when combined with Golimumab. |
Pazopanib | Pazopanib The metabolism of Copanlisib can be decreased when combined with Pazopanib. |
Albendazole | Albendazole The metabolism of Copanlisib can be decreased when combined with Albendazole. |
Levonorgestrel | Levonorgestrel The metabolism of Copanlisib can be decreased when combined with Levonorgestrel. |
Tocilizumab Injection | Tocilizumab Injection The metabolism of Copanlisib can be increased when combined with Tocilizumab. |
Cabazitaxel Injection | Cabazitaxel Injection The metabolism of Copanlisib can be decreased when combined with Cabazitaxel. |
Acetaminophen Injection | Acetaminophen Injection The metabolism of Copanlisib can be increased when combined with Acetaminophen. |
Denileukin Diftitox Injection | Denileukin Diftitox Injection The metabolism of Copanlisib can be decreased when combined with Aldesleukin. |
Roflumilast | Roflumilast The metabolism of Copanlisib can be decreased when combined with Roflumilast. |
Linagliptin | Linagliptin The serum concentration of Copanlisib can be increased when it is combined with Linagliptin. |
Rilpivirine | Rilpivirine The metabolism of Copanlisib can be decreased when combined with Rilpivirine. |
Telaprevir | Telaprevir The serum concentration of Copanlisib can be increased when it is combined with Glecaprevir. |
Cyclophosphamide Injection | Cyclophosphamide Injection The metabolism of Copanlisib can be increased when combined with Cyclophosphamide. |
Rivaroxaban | Rivaroxaban The metabolism of Copanlisib can be decreased when combined with Rivaroxaban. |
Ticagrelor | Ticagrelor The serum concentration of Ticagrelor can be increased when it is combined with Copanlisib. |
Brentuximab Vedotin Injection | Brentuximab Vedotin Injection The metabolism of Copanlisib can be decreased when combined with Brentuximab vedotin. |
Vandetanib | Vandetanib The serum concentration of Copanlisib can be increased when it is combined with Vandetanib. |
Clobazam | Clobazam The metabolism of Copanlisib can be increased when combined with Clobazam. |
Vemurafenib | Vemurafenib The serum concentration of Copanlisib can be increased when it is combined with Vemurafenib. |
Vismodegib | Vismodegib Vismodegib may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Ivacaftor | Ivacaftor The serum concentration of Copanlisib can be increased when it is combined with Ivacaftor. |
Axitinib | Axitinib The metabolism of Copanlisib can be decreased when combined with Axitinib. |
Crizotinib | Crizotinib The metabolism of Copanlisib can be decreased when combined with Crizotinib. |
Cabergoline | Cabergoline The metabolism of Copanlisib can be decreased when combined with Cabergoline. |
Naloxone Injection | Naloxone Injection The metabolism of Copanlisib can be decreased when combined with Naloxone. |
Ambrisentan | Ambrisentan The metabolism of Copanlisib can be decreased when combined with Ambrisentan. |
Carfilzomib Injection | Carfilzomib Injection The serum concentration of Copanlisib can be increased when it is combined with Carfilzomib. |
Enzalutamide | Enzalutamide The serum concentration of Copanlisib can be increased when it is combined with Enzalutamide. |
Mirabegron | Mirabegron The serum concentration of Copanlisib can be increased when it is combined with Mirabegron. |
Regorafenib | Regorafenib The serum concentration of Copanlisib can be increased when it is combined with Regorafenib. |
Bosutinib | Bosutinib The metabolism of Copanlisib can be decreased when combined with Bosutinib. |
Corticotropin, Repository Injection | Corticotropin, Repository Injection The metabolism of Copanlisib can be increased when combined with Corticotropin. |
Teriflunomide | Teriflunomide Teriflunomide may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Ponatinib | Ponatinib The serum concentration of Copanlisib can be increased when it is combined with Ponatinib. |
Pomalidomide | Pomalidomide The serum concentration of Copanlisib can be increased when it is combined with Pomalidomide. |
Ado-trastuzumab Emtansine Injection | Ado-trastuzumab Emtansine Injection The metabolism of Copanlisib can be decreased when combined with Trastuzumab emtansine. |
Apixaban | Apixaban The metabolism of Copanlisib can be decreased when combined with Apixaban. |
Canagliflozin | Canagliflozin The serum concentration of Copanlisib can be increased when it is combined with Canagliflozin. |
Dabrafenib | Dabrafenib The metabolism of Copanlisib can be increased when combined with Dabrafenib. |
Trametinib | Trametinib The metabolism of Copanlisib can be increased when combined with Trametinib. |
Dolutegravir | Dolutegravir The serum concentration of Copanlisib can be increased when it is combined with Dolutegravir. |
Afatinib | Afatinib The serum concentration of Copanlisib can be increased when it is combined with Afatinib. |
Vortioxetine | Vortioxetine The metabolism of Copanlisib can be decreased when combined with Vortioxetine. |
Perampanel | Perampanel The metabolism of Copanlisib can be increased when combined with Perampanel. |
Ibrutinib | Ibrutinib The metabolism of Copanlisib can be decreased when combined with Ibrutinib. |
Lomitapide | Lomitapide The serum concentration of Lomitapide can be increased when it is combined with Copanlisib. |
Simeprevir | Simeprevir The serum concentration of Copanlisib can be increased when it is combined with Simeprevir. |
Sofosbuvir | Sofosbuvir The serum concentration of Copanlisib can be increased when it is combined with Sofosbuvir. |
Apremilast | Apremilast The metabolism of Copanlisib can be increased when combined with Apremilast. |
Ceritinib | Ceritinib The metabolism of Copanlisib can be decreased when combined with Ceritinib. |
Siltuximab Injection | Siltuximab Injection The metabolism of Copanlisib can be increased when combined with Siltuximab. |
Eslicarbazepine | Eslicarbazepine The metabolism of Copanlisib can be increased when combined with Eslicarbazepine. |
Belinostat Injection | Belinostat Injection The serum concentration of Copanlisib can be increased when it is combined with Belinostat. |
Idelalisib | Idelalisib The metabolism of Copanlisib can be decreased when combined with Idelalisib. |
Testosterone Injection | Testosterone Injection The metabolism of Copanlisib can be increased when combined with Testosterone. |
Oritavancin Injection | Oritavancin Injection The metabolism of Copanlisib can be increased when combined with Oritavancin. |
Vorapaxar | Vorapaxar The serum concentration of Copanlisib can be increased when it is combined with Vorapaxar. |
Suvorexant | Suvorexant The serum concentration of Copanlisib can be increased when it is combined with Suvorexant. |
Edoxaban | Edoxaban The serum concentration of Copanlisib can be increased when it is combined with Edoxaban. |
Olaparib | Olaparib The metabolism of Copanlisib can be decreased when combined with Olaparib. |
Tasimelteon | Tasimelteon The metabolism of Copanlisib can be decreased when combined with Tasimelteon. |
Lanreotide Injection | Lanreotide Injection The metabolism of Copanlisib can be decreased when combined with Lanreotide. |
Nintedanib | Nintedanib The metabolism of Copanlisib can be decreased when combined with Nintedanib. |
Secukinumab Injection | Secukinumab Injection The metabolism of Copanlisib can be increased when combined with Secukinumab. |
Risperidone Injection | Risperidone Injection The metabolism of Copanlisib can be decreased when combined with Risperidone. |
Palbociclib | Palbociclib The serum concentration of Copanlisib can be increased when it is combined with Palbociclib. |
Lenvatinib | Lenvatinib The metabolism of Copanlisib can be increased when combined with Lenvatinib. |
Panobinostat | Panobinostat The serum concentration of Copanlisib can be increased when it is combined with Panobinostat. |
Haloperidol Injection | Haloperidol Injection The serum concentration of Copanlisib can be increased when it is combined with Haloperidol. |
Isavuconazonium Injection | Isavuconazonium Injection The serum concentration of Copanlisib can be increased when it is combined with Isavuconazonium. |
Flibanserin | Flibanserin The serum concentration of Copanlisib can be increased when it is combined with Flibanserin. |
Rolapitant | Rolapitant The serum concentration of Copanlisib can be increased when it is combined with Rolapitant. |
Prednisolone | Prednisolone The metabolism of Copanlisib can be increased when combined with Prednisolone. |
Daclatasvir | Daclatasvir The serum concentration of Copanlisib can be increased when it is combined with Daclatasvir. |
Ziprasidone Injection | Ziprasidone Injection The metabolism of Copanlisib can be decreased when combined with Ziprasidone. |
Cobimetinib | Cobimetinib The metabolism of Copanlisib can be decreased when combined with Cobimetinib. |
Osimertinib | Osimertinib The metabolism of Copanlisib can be increased when combined with Osimertinib. |
Alectinib | Alectinib Alectinib may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Rifapentine | Rifapentine The metabolism of Copanlisib can be increased when combined with Rifapentine. |
Lesinurad | Lesinurad The metabolism of Copanlisib can be increased when combined with Lesinurad. |
Amphotericin B Liposomal Injection | Amphotericin B Liposomal Injection The metabolism of Copanlisib can be decreased when combined with Amphotericin B. |
Dexamethasone Injection | Dexamethasone Injection The metabolism of Copanlisib can be increased when combined with Dexamethasone. |
Venetoclax | Venetoclax The serum concentration of Copanlisib can be increased when it is combined with Venetoclax. |
Cobicistat | Cobicistat The serum concentration of Copanlisib can be increased when it is combined with Cobicistat. |
Selexipag | Selexipag The serum concentration of Copanlisib can be increased when it is combined with Selexipag. |
Rucaparib | Rucaparib The serum concentration of Copanlisib can be increased when it is combined with Rucaparib. |
Ribociclib | Ribociclib The metabolism of Copanlisib can be decreased when combined with Ribociclib. |
Brigatinib | Brigatinib The metabolism of Copanlisib can be increased when combined with Brigatinib. |
Deutetrabenazine | Deutetrabenazine The metabolism of Copanlisib can be decreased when combined with Deutetrabenazine. |
Valbenazine | Valbenazine The metabolism of Copanlisib can be decreased when combined with Valbenazine. |
Deflazacort | Deflazacort The metabolism of Copanlisib can be increased when combined with Deflazacort. |
Safinamide | Safinamide The metabolism of Copanlisib can be decreased when combined with Safinamide. |
Sarilumab Injection | Sarilumab Injection The metabolism of Copanlisib can be increased when combined with Sarilumab. |
Midostaurin | Midostaurin The metabolism of Copanlisib can be increased when combined with Midostaurin. |
Neratinib | Neratinib The serum concentration of Copanlisib can be increased when it is combined with Neratinib. |
Enasidenib | Enasidenib The serum concentration of Copanlisib can be increased when it is combined with Enasidenib. |
Inotuzumab Ozogamicin Injection | Inotuzumab Ozogamicin Injection The serum concentration of Copanlisib can be increased when it is combined with Inotuzumab ozogamicin. |
Aprepitant/Fosaprepitant Injection | Aprepitant/Fosaprepitant Injection The metabolism of Copanlisib can be increased when combined with Fosaprepitant. |
Abemaciclib | Abemaciclib Abemaciclib may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Betrixaban | Betrixaban The serum concentration of Copanlisib can be increased when it is combined with Betrixaban. |
Acalabrutinib | Acalabrutinib The metabolism of Copanlisib can be decreased when combined with Acalabrutinib. |
Letermovir | Letermovir The metabolism of Copanlisib can be decreased when combined with Letermovir. |
Ertugliflozin | Ertugliflozin The serum concentration of Copanlisib can be increased when it is combined with Ertugliflozin. |
Buprenorphine Injection | Buprenorphine Injection The metabolism of Copanlisib can be decreased when combined with Buprenorphine. |
Apalutamide | Apalutamide The serum concentration of Copanlisib can be decreased when it is combined with Apalutamide. |
Fostamatinib | Fostamatinib The metabolism of Copanlisib can be decreased when combined with Fostamatinib. |
Avatrombopag | Avatrombopag Avatrombopag may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Baricitinib | Baricitinib The excretion of Baricitinib can be decreased when combined with Copanlisib. |
Eliglustat | Eliglustat The serum concentration of Copanlisib can be increased when it is combined with Eliglustat. |
Binimetinib | Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Copanlisib. |
Ivosidenib | Ivosidenib The serum concentration of Copanlisib can be increased when it is combined with Ivosidenib. |
Lusutrombopag | Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Copanlisib. |
Elagolix | Elagolix The serum concentration of Copanlisib can be increased when it is combined with Elagolix. |
Doravirine | Doravirine The metabolism of Copanlisib can be decreased when combined with Doravirine. |
Cannabidiol | Cannabidiol The metabolism of Copanlisib can be decreased when combined with Cannabidiol. |
Dacomitinib | Dacomitinib The serum concentration of Copanlisib can be increased when it is combined with Dacomitinib. |
Duvelisib | Duvelisib The metabolism of Copanlisib can be decreased when combined with Duvelisib. |
Omadacycline | Omadacycline The serum concentration of Copanlisib can be increased when it is combined with Omadacycline. |
Sarecycline | Sarecycline The serum concentration of Copanlisib can be increased when it is combined with Sarecycline. |
Stiripentol | Stiripentol The metabolism of Copanlisib can be decreased when combined with Stiripentol. |
Talazoparib | Talazoparib The serum concentration of Copanlisib can be increased when it is combined with Talazoparib. |
Gilteritinib | Gilteritinib The metabolism of Copanlisib can be decreased when combined with Gilteritinib. |
Glasdegib | Glasdegib The serum concentration of Copanlisib can be increased when it is combined with Glasdegib. |
Lorlatinib | Lorlatinib The metabolism of Copanlisib can be decreased when combined with Lorlatinib. |
Larotrectinib | Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Copanlisib. |
Methoxy Polyethylene Glycol-Epoetin Beta Injection | Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Copanlisib. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Copanlisib. |
Rifamycin | Rifamycin The serum concentration of Copanlisib can be increased when it is combined with Rifamycin. |
Prucalopride | Prucalopride The metabolism of Copanlisib can be decreased when combined with Prucalopride. |
Emapalumab-lzsg Injection | Emapalumab-lzsg Injection The metabolism of Copanlisib can be increased when combined with Emapalumab. |
Siponimod | Siponimod The metabolism of Copanlisib can be decreased when combined with Siponimod. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic The excretion of Acyclovir can be decreased when combined with Copanlisib. |
Erdafitinib | Erdafitinib The serum concentration of Copanlisib can be increased when it is combined with Erdafitinib. |
Alpelisib | Alpelisib The metabolism of Copanlisib can be increased when combined with Alpelisib. |
Darolutamide | Darolutamide Darolutamide may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Triclabendazole | Triclabendazole The metabolism of Copanlisib can be decreased when combined with Triclabendazole. |
Entrectinib | Entrectinib The serum concentration of Copanlisib can be increased when it is combined with Entrectinib. |
Istradefylline | Istradefylline The serum concentration of Copanlisib can be increased when it is combined with Istradefylline. |
Pitolisant | Pitolisant The serum concentration of Copanlisib can be decreased when it is combined with Pitolisant. |
Fedratinib | Fedratinib The serum concentration of Copanlisib can be increased when it is combined with Fedratinib. |
Lefamulin | Lefamulin The serum concentration of Lefamulin can be increased when it is combined with Copanlisib. |
Phenytoin Injection | Phenytoin Injection The metabolism of Copanlisib can be increased when combined with Phenytoin. |
Fosphenytoin Injection | Fosphenytoin Injection The metabolism of Copanlisib can be increased when combined with Fosphenytoin. |
Enfortumab vedotin-ejfv Injection | Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Copanlisib. |
Voxelotor | Voxelotor The serum concentration of Copanlisib can be increased when it is combined with Voxelotor. |
Lasmiditan | Lasmiditan The serum concentration of Copanlisib can be increased when it is combined with Lasmiditan. |
Ubrogepant | Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Copanlisib. |
Tazemetostat | Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Copanlisib. |
Cenobamate | Cenobamate The serum concentration of Copanlisib can be decreased when it is combined with Cenobamate. |
Selumetinib | Selumetinib The metabolism of Copanlisib can be decreased when combined with Selumetinib. |
Rimegepant | Rimegepant The serum concentration of Copanlisib can be increased when it is combined with Rimegepant. |
Tucatinib | Tucatinib Tucatinib may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Remdesivir Injection | Remdesivir Injection The serum concentration of Copanlisib can be increased when it is combined with Remdesivir. |
Ripretinib | Ripretinib The serum concentration of Copanlisib can be increased when it is combined with Ripretinib. |
Capmatinib | Capmatinib The serum concentration of Copanlisib can be increased when it is combined with Capmatinib. |
Lemborexant | Lemborexant The metabolism of Copanlisib can be decreased when combined with Lemborexant. |
Fostemsavir | Fostemsavir Fostemsavir may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Octreotide | Octreotide The serum concentration of Copanlisib can be increased when it is combined with Octreotide. |
Belantamab Mafodotin-blmf Injection | Belantamab Mafodotin-blmf Injection The serum concentration of Copanlisib can be increased when it is combined with Belantamab mafodotin. |
Pralsetinib | Pralsetinib The serum concentration of Copanlisib can be increased when it is combined with Pralsetinib. |
Satralizumab-mwge Injection | Satralizumab-mwge Injection The serum concentration of Copanlisib can be decreased when it is combined with Satralizumab. |
Progestin-Only (drospirenone) Oral Contraceptives | Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Copanlisib can be decreased when combined with Drospirenone. |
Vitamin E (Alpha-Tocopherol) | Vitamin E (Alpha-Tocopherol) The metabolism of Copanlisib can be increased when combined with Vitamin E. |
Trazodone | Trazodone The serum concentration of Copanlisib can be decreased when it is combined with Trazodone. |
Phenobarbital | Phenobarbital The metabolism of Copanlisib can be increased when combined with Phenobarbital. |
Primidone | Primidone The metabolism of Copanlisib can be increased when combined with Primidone. |
Chlorpromazine | Chlorpromazine The metabolism of Copanlisib can be increased when combined with Chlorpromazine. |
Diazepam | Diazepam The metabolism of Copanlisib can be decreased when combined with Diazepam. |
Lorazepam | Lorazepam The metabolism of Copanlisib can be decreased when combined with Lorazepam. |
Bromocriptine | Bromocriptine The metabolism of Copanlisib can be decreased when combined with Bromocriptine. |
Tranylcypromine | Tranylcypromine The metabolism of Copanlisib can be decreased when combined with Tranylcypromine. |
Phenelzine | Phenelzine The metabolism of Copanlisib can be decreased when combined with Phenelzine. |
Tetracycline | Tetracycline The metabolism of Copanlisib can be decreased when combined with Tetracycline. |
Prochlorperazine | Prochlorperazine The metabolism of Copanlisib can be decreased when combined with Prochlorperazine. |
Dapsone | Dapsone The metabolism of Copanlisib can be decreased when combined with Dapsone. |
Oxycodone | Oxycodone The metabolism of Copanlisib can be decreased when combined with Oxycodone. |
Methadone | Methadone The metabolism of Copanlisib can be increased when combined with Methadone. |
Oxybutynin | Oxybutynin The metabolism of Copanlisib can be decreased when combined with Oxybutynin. |
Orphenadrine | Orphenadrine The metabolism of Copanlisib can be decreased when combined with Orphenadrine. |
Phentermine | Phentermine The metabolism of Copanlisib can be decreased when combined with Phentermine. |
Sulfasalazine | Sulfasalazine Sulfasalazine may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Hydrocortisone | Hydrocortisone The metabolism of Copanlisib can be increased when combined with Hydrocortisone. |
Doxorubicin | Doxorubicin The metabolism of Copanlisib can be decreased when combined with Doxorubicin. |
Dactinomycin | Dactinomycin The serum concentration of Copanlisib can be increased when it is combined with Dactinomycin. |
Carbamazepine | Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Copanlisib. |
Clonidine | Clonidine The metabolism of Copanlisib can be decreased when combined with Clonidine. |
Hydralazine | Hydralazine The metabolism of Copanlisib can be decreased when combined with Hydralazine. |
Cimetidine | Cimetidine The metabolism of Copanlisib can be decreased when combined with Cimetidine. |
Warfarin | Warfarin The metabolism of Copanlisib can be increased when combined with Warfarin. |
Loperamide | Loperamide The metabolism of Copanlisib can be decreased when combined with Loperamide. |
Daunorubicin | Daunorubicin The metabolism of Copanlisib can be decreased when combined with Daunorubicin. |
Griseofulvin | Griseofulvin The metabolism of Copanlisib can be increased when combined with Griseofulvin. |
Digoxin | Digoxin The serum concentration of Digoxin can be increased when it is combined with Copanlisib. |
Loxapine | Loxapine The serum concentration of Copanlisib can be increased when it is combined with Loxapine. |
Chloroquine | Chloroquine The metabolism of Copanlisib can be decreased when combined with Chloroquine. |
Quinine | Quinine The serum concentration of Copanlisib can be increased when it is combined with Quinine. |
Calcitriol | Calcitriol The metabolism of Copanlisib can be increased when combined with Calcitriol. |
Sulfinpyrazone | Sulfinpyrazone The metabolism of Copanlisib can be increased when combined with Sulfinpyrazone. |
Clindamycin Injection | Clindamycin Injection The metabolism of Copanlisib can be decreased when combined with Clindamycin. |
Secobarbital | Secobarbital The metabolism of Copanlisib can be increased when combined with Secobarbital. |
Desipramine | Desipramine The metabolism of Copanlisib can be decreased when combined with Desipramine. |
Amitriptyline | Amitriptyline The metabolism of Copanlisib can be decreased when combined with Amitriptyline. |
Imipramine | Imipramine The metabolism of Copanlisib can be decreased when combined with Imipramine. |
Probenecid | Probenecid The metabolism of Copanlisib can be increased when combined with Probenecid. |
Quinidine | Quinidine The metabolism of Quinidine can be decreased when combined with Copanlisib. |
Procainamide | Procainamide The excretion of Procainamide can be decreased when combined with Copanlisib. |
Isoniazid | Isoniazid The metabolism of Copanlisib can be decreased when combined with Isoniazid. |
Rifampin | Rifampin The metabolism of Copanlisib can be increased when combined with Rifampicin. |
Valproic Acid | Valproic Acid The metabolism of Copanlisib can be decreased when combined with Valproic acid. |
Tamoxifen | Tamoxifen The serum concentration of Copanlisib can be increased when it is combined with Tamoxifen. |
Levothyroxine | Levothyroxine The serum concentration of Copanlisib can be decreased when it is combined with Levothyroxine. |
Methimazole | Methimazole The metabolism of Copanlisib can be decreased when combined with Methimazole. |
Dextromethorphan | Dextromethorphan The metabolism of Copanlisib can be decreased when combined with Dextromethorphan. |
Niacin | Niacin The metabolism of Copanlisib can be decreased when combined with Niacin. |
Chlorpheniramine | Chlorpheniramine The metabolism of Copanlisib can be decreased when combined with Chlorpheniramine. |
Danazol | Danazol The metabolism of Copanlisib can be decreased when combined with Danazol. |
Disulfiram | Disulfiram The metabolism of Copanlisib can be decreased when combined with Disulfiram. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The metabolism of Copanlisib can be decreased when combined with Propranolol. |
Nortriptyline | Nortriptyline The serum concentration of Nortriptyline can be increased when it is combined with Copanlisib. |
Amphotericin B Injection | Amphotericin B Injection The metabolism of Copanlisib can be decreased when combined with Amphotericin B. |
Nadolol | Nadolol The excretion of Nadolol can be decreased when combined with Copanlisib. |
Clomiphene | Clomiphene The serum concentration of Copanlisib can be increased when it is combined with Clomifene. |
Colchicine | Colchicine The metabolism of Copanlisib can be increased when combined with Colchicine. |
Cephalexin | Cephalexin The metabolism of Copanlisib can be decreased when combined with Cephalexin. |
Acetazolamide | Acetazolamide The metabolism of Copanlisib can be decreased when combined with Acetazolamide. |
Ketoconazole | Ketoconazole The serum concentration of Copanlisib can be increased when it is combined with Ketoconazole. |
Vincristine Injection | Vincristine Injection The metabolism of Vincristine can be decreased when combined with Copanlisib. |
Vinblastine | Vinblastine The metabolism of Copanlisib can be increased when combined with Vinblastine. |
Metoprolol | Metoprolol The metabolism of Copanlisib can be decreased when combined with Metoprolol. |
Hydroxyzine | Hydroxyzine The metabolism of Copanlisib can be decreased when combined with Hydroxyzine. |
Alprazolam | Alprazolam The metabolism of Copanlisib can be decreased when combined with Alprazolam. |
Triazolam | Triazolam The metabolism of Copanlisib can be decreased when combined with Triazolam. |
Diltiazem | Diltiazem The metabolism of Copanlisib can be decreased when combined with Diltiazem. |
Nifedipine | Nifedipine The metabolism of Copanlisib can be increased when combined with Nifedipine. |
Verapamil | Verapamil The serum concentration of Copanlisib can be increased when it is combined with Verapamil. |
Etoposide | Etoposide The metabolism of Copanlisib can be increased when combined with Etoposide. |
Glyburide | Glyburide The metabolism of Copanlisib can be decreased when combined with Glyburide. |
Dicloxacillin | Dicloxacillin The metabolism of Copanlisib can be increased when combined with Dicloxacillin. |
Nafcillin Injection | Nafcillin Injection The metabolism of Copanlisib can be increased when combined with Nafcillin. |
Pentamidine Injection | Pentamidine Injection The metabolism of Copanlisib can be decreased when combined with Pentamidine. |
Pimozide | Pimozide The metabolism of Pimozide can be decreased when combined with Copanlisib. |
Amiodarone | Amiodarone The serum concentration of Amiodarone can be increased when it is combined with Copanlisib. |
Buspirone | Buspirone The metabolism of Copanlisib can be decreased when combined with Buspirone. |
Lovastatin | Lovastatin The metabolism of Copanlisib can be decreased when combined with Lovastatin. |
Ciprofloxacin | Ciprofloxacin The metabolism of Copanlisib can be decreased when combined with Ciprofloxacin. |
Clozapine | Clozapine The metabolism of Copanlisib can be increased when combined with Clozapine. |
Clarithromycin | Clarithromycin The serum concentration of Copanlisib can be increased when it is combined with Clarithromycin. |
Felodipine | Felodipine The metabolism of Copanlisib can be decreased when combined with Felodipine. |
Pravastatin | Pravastatin Pravastatin may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Simvastatin | Simvastatin The serum concentration of Simvastatin can be increased when it is combined with Copanlisib. |
Epoetin Alfa, Injection | Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Copanlisib. |
Teniposide Injection | Teniposide Injection The metabolism of Copanlisib can be decreased when combined with Teniposide. |
Itraconazole | Itraconazole The serum concentration of Copanlisib can be increased when it is combined with Itraconazole. |
Rifabutin | Rifabutin The metabolism of Copanlisib can be increased when combined with Rifabutin. |
Bisoprolol | Bisoprolol The serum concentration of Copanlisib can be increased when it is combined with Bisoprolol. |
Doxazosin | Doxazosin The metabolism of Copanlisib can be decreased when combined with Doxazosin. |
Isradipine | Isradipine The metabolism of Copanlisib can be decreased when combined with Isradipine. |
Omeprazole | Omeprazole The metabolism of Copanlisib can be increased when combined with Omeprazole. |
Cisapride | Cisapride The metabolism of Copanlisib can be decreased when combined with Cisapride. |
Fluvastatin | Fluvastatin The metabolism of Copanlisib can be decreased when combined with Fluvastatin. |
Venlafaxine | Venlafaxine Venlafaxine may increase the excretion rate of Copanlisib which could result in a lower serum level and potentially a reduction in efficacy. |
Famciclovir | Famciclovir The metabolism of Copanlisib can be decreased when combined with Famciclovir. |
Fluvoxamine | Fluvoxamine The metabolism of Copanlisib can be decreased when combined with Fluvoxamine. |
Nefazodone | Nefazodone The metabolism of Copanlisib can be decreased when combined with Nefazodone. |
Losartan | Losartan The metabolism of Copanlisib can be decreased when combined with Losartan. |
Lansoprazole | Lansoprazole The metabolism of Copanlisib can be increased when combined with Lansoprazole. |
Ifosfamide Injection | Ifosfamide Injection The metabolism of Copanlisib can be increased when combined with Ifosfamide. |
Nicardipine | Nicardipine The metabolism of Copanlisib can be decreased when combined with Nicardipine. |
Ticlopidine | Ticlopidine The metabolism of Copanlisib can be decreased when combined with Ticlopidine. |
Saquinavir | Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Copanlisib. |
Metformin | Metformin The excretion of Metformin can be decreased when combined with Copanlisib. |
Nisoldipine | Nisoldipine The metabolism of Copanlisib can be decreased when combined with Nisoldipine. |
Gemcitabine Injection | Gemcitabine Injection The serum concentration of Copanlisib can be increased when it is combined with Gemcitabine. |
Indinavir | Indinavir The metabolism of Copanlisib can be decreased when combined with Indinavir. |
Ritonavir | Ritonavir The serum concentration of Copanlisib can be increased when it is combined with Ritonavir. |
Docetaxel Injection | Docetaxel Injection The metabolism of Copanlisib can be decreased when combined with Docetaxel. |
Zafirlukast | Zafirlukast The metabolism of Copanlisib can be decreased when combined with Zafirlukast. |
Mirtazapine | Mirtazapine The metabolism of Copanlisib can be decreased when combined with Mirtazapine. |
Topiramate | Topiramate The metabolism of Copanlisib can be increased when combined with Topiramate. |
Nelfinavir | Nelfinavir The metabolism of Copanlisib can be decreased when combined with Nelfinavir. |
Fexofenadine | Fexofenadine The serum concentration of Copanlisib can be increased when it is combined with Fexofenadine. |
Azithromycin | Azithromycin The metabolism of Copanlisib can be decreased when combined with Azithromycin. |
Carvedilol | Carvedilol The serum concentration of Copanlisib can be increased when it is combined with Carvedilol. |
Flutamide | Flutamide The metabolism of Copanlisib can be decreased when combined with Flutamide. |
Bicalutamide | Bicalutamide The metabolism of Copanlisib can be decreased when combined with Bicalutamide. |
Propafenone | Propafenone The serum concentration of Copanlisib can be increased when it is combined with Propafenone. |
Raloxifene | Raloxifene The metabolism of Copanlisib can be decreased when combined with Raloxifene. |
Irbesartan | Irbesartan The metabolism of Copanlisib can be decreased when combined with Irbesartan. |
Finasteride | Finasteride The metabolism of Copanlisib can be decreased when combined with Finasteride. |
Quetiapine | Quetiapine The metabolism of Copanlisib can be decreased when combined with Quetiapine. |
Paroxetine | Paroxetine The metabolism of Copanlisib can be decreased when combined with Paroxetine. |
Citalopram | Citalopram The metabolism of Copanlisib can be decreased when combined with Citalopram. |
Efavirenz | Efavirenz The metabolism of Copanlisib can be increased when combined with Efavirenz. |
Sildenafil | Sildenafil The serum concentration of Sildenafil can be increased when it is combined with Copanlisib. |
Thalidomide | Thalidomide The metabolism of Copanlisib can be increased when combined with Thalidomide. |
Nateglinide | Nateglinide The metabolism of Copanlisib can be decreased when combined with Nateglinide. |
Rabeprazole | Rabeprazole The metabolism of Copanlisib can be decreased when combined with Rabeprazole. |
Terbinafine | Terbinafine The metabolism of Copanlisib can be increased when combined with Terbinafine. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists