Diphenhydramine
Generic name: Pronounced as (dye fen hye' dra meen)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 01/15/2022
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Brand names of combination products
- Drug interactions
Why is this medication prescribed?
Diphenhydramine is used to relieve red, irritated, itchy, watery eyes; sneezing; and runny nose caused by hay fever, allergies, or the common cold. Diphenhydramine is also used to relieve cough caused by minor throat or airway irritation. Diphenhydramine is also used to prevent and treat motion sickness, and to treat insomnia (difficulty falling asleep or staying asleep). Diphenhydramine is also used to control abnormal movements in people who have early stage parkinsonian syndrome (a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) or who are experiencing movement problems as a side effect of a medication.
Diphenhydramine will relieve the symptoms of these conditions but will not treat the cause of the symptoms or speed recovery. Diphenhydramine should not be used to cause sleepiness in children. Diphenhydramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.
How should this medicine be used?
Diphenhydramine comes as a tablet, a rapidly disintegrating (dissolving) tablet, a capsule, a liquid-filled capsule, a dissolving strip, powder, and a liquid to take by mouth. When diphenhydramine is used for the relief of allergies, cold, and cough symptoms, it is usually taken every 4 to 6 hours. When diphenhydramine is used to treat motion sickness, it is usually taken 30 minutes before departure and, if needed, before meals and at bedtime. When diphenhydramine is used to treat insomnia it is taken at bedtime (30 minutes before planned sleep). When diphenhydramine is used to treat abnormal movements, it is usually taken three times a day at first and then taken 4 times a day. Follow the directions on the package or on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take diphenhydramine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor or directed on the label.
Diphenhydramine comes alone and in combination with pain relievers, fever reducers, and decongestants. Ask your doctor or pharmacist for advice on which product is best for your symptoms. Check nonprescription cough and cold product labels carefully before using two or more products at the same time. These products may contain the same active ingredient(s) and taking them together could cause you to receive an overdose. This is especially important if you will be giving cough and cold medications to a child.
Nonprescription cough and cold combination products, including products that contain diphenhydramine, can cause serious side effects or death in young children. Do not give these products to children younger than 4 years of age. If you give these products to children 4 to 11 years of age, use caution and follow the package directions carefully.
If you are giving diphenhydramine or a combination product that contains diphenhydramine to a child, read the package label carefully to be sure that it is the right product for a child of that age. Do not give diphenhydramine products that are made for adults to children.
Before you give a diphenhydramine product to a child, check the package label to find out how much medication the child should receive. Give the dose that matches the child's age on the chart. Ask the child's doctor if you don't know how much medication to give the child.
If you are taking the liquid, do not use a household spoon to measure your dose. Use the measuring spoon or cup that came with the medication or use a spoon made especially for measuring medication.
If you are taking the dissolving strips, place the strips on your tongue one at a time and swallow after they melt.
If you are taking the rapidly dissolving tablets, place a tablet on your tongue and close your mouth. The tablet will quickly dissolve and can be swallowed with or without water.
If you are taking the capsules, swallow them whole. Do not try to break the capsules.
Other uses for this medicine
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking diphenhydramine,
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tell your doctor and pharmacist if you are allergic to diphenhydramine, any other medications, or any of the ingredients in diphenhydramine preparations. Ask your doctor or pharmacist or check the package label for a list of the ingredients.
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tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: other diphenhydramine products (even those that are used on the skin); other medications for colds, hay fever, or allergies; medications for anxiety, depression, or seizures; muscle relaxants; narcotic medications for pain; sedatives; sleeping pills; and tranquilizers.
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tell your doctor if you have or have ever had asthma, emphysema, chronic bronchitis, or other types of lung disease; glaucoma (a condition in which increased pressure in the eye can lead to gradual loss of vision); ulcers; difficulty urinating (due to an enlarged prostate gland); heart disease; high blood pressure; seizures; or an overactive thyroid gland.If you will be using the liquid, tell your doctor if you have been told to follow a low-sodium diet.
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tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking diphenhydramine, call your doctor.
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you should know that generally diphenhydramine should not be used in older adults, except to manage serious allergic reactions, because it is not as safe or effective as other medication(s) to treat your condition. If you are 65 years of age or older, talk to your doctor about the risks and benefits of taking this medication.
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if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking diphenhydramine.
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you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
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remember that alcohol can add to the drowsiness caused by this medication. Avoid alcoholic beverages while you are taking this medication.
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if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent damage to your brain that can cause severe intellectual disability), you should know that some brands of chewable tablets and rapidly disintegrating tablets that contain diphenhydramine may be sweetened with aspartame, a source of phenylalanine.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Diphenhydramine is usually taken as needed. If your doctor has told you to take diphenhydramine regularly, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Diphenhydramine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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dry mouth, nose, and throat
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drowsiness
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dizziness
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nausea
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vomiting
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loss of appetite
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constipation
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increased chest congestion
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headache
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muscle weakness
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excitement (especially in children)
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nervousness
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Some side effects may be serious. If you experience any of the following symptoms, call your doctor immediately:
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vision problems
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difficulty urinating or painful urination
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Diphenhydramine may cause other side effects. Call your doctor if you experience any unusual problems while you are taking this medication.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
What OTHER INFORMATION should I know?
Ask your pharmacist any questions you have about diphenhydramine.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Brand names of combination products
- Advil PM® (containing Diphenhydramine, Ibuprofen)
- Alahist LQ® (containing Diphenhydramine, Phenylephrine)
- Aldex CT® (containing Diphenhydramine, Phenylephrine)
- Aleve PM® (containing Diphenhydramine, Naproxen)
- Anacin P.M. Aspirin Free® (containing Acetaminophen, Diphenhydramine)
- Bayer Aspirin PM® (containing Aspirin, Diphenhydramine)
- Benadryl-D Allergy Plus Sinus® (containing Diphenhydramine, Phenylephrine)
- Children's Dimetapp Nighttime Cold and Congestion® (containing Diphenhydramine, Phenylephrine)
- Doans PM® (containing Diphenhydramine, Magnesium Salicylate)
- Endal HD® (containing Diphenhydramine, Phenylephrine)
- Excedrin PM® (containing Acetaminophen, Diphenhydramine)
- Goody's PM® (containing Acetaminophen, Diphenhydramine)
- Legatrin PM® (containing Acetaminophen, Diphenhydramine)
- Masophen PM® (containing Acetaminophen, Diphenhydramine)
- Midol PM® (containing Acetaminophen, Diphenhydramine)
- Motrin PM® (containing Diphenhydramine, Ibuprofen)
- PediaCare Children's Allergy and Cold® (containing Diphenhydramine, Phenylephrine)
- Robitussin Night Time Cough and Cold® (containing Diphenhydramine, Phenylephrine)
- Sudafed PE Day/Night Cold® (containing Acetaminophen, Dextromethorphan, Diphenhydramine, Guaifenesin, Phenylephrine)
- Sudafed PE Day/Night Congestion® (containing Diphenhydramine, Phenylephrine)
- Sudafed PE Severe Cold® (containing Acetaminophen, Diphenhydramine, Phenylephrine)
- Tekral® (containing Diphenhydramine, Pseudoephedrine)
- Theraflu Nighttime Severe Cold and Cough® (containing Acetaminophen, Diphenhydramine, Phenylephrine)
- Triaminic Night Time Cold and Cough® (containing Diphenhydramine, Phenylephrine)
- Tylenol Allergy Multi-Symptom Nighttime® (containing Acetaminophen, Diphenhydramine, Phenylephrine)
- Tylenol Severe Allergy® (containing Acetaminophen, Diphenhydramine)
- Unisom with Pain Relief® (containing Acetaminophen, Diphenhydramine)
Drug interactions
Drug | Interaction |
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Moxifloxacin | Moxifloxacin The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Moxifloxacin. |
Montelukast | Montelukast The metabolism of Diphenhydramine can be decreased when combined with Montelukast. |
Leflunomide | Leflunomide The metabolism of Diphenhydramine can be decreased when combined with Leflunomide. |
Delavirdine | Delavirdine The metabolism of Diphenhydramine can be decreased when combined with Delavirdine. |
Nevirapine | Nevirapine The metabolism of Diphenhydramine can be decreased when combined with Nevirapine. |
Dolasetron | Dolasetron The risk or severity of adverse effects can be increased when Dolasetron is combined with Diphenhydramine. |
Anagrelide | Anagrelide The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Anagrelide. |
Bisacodyl | Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Diphenhydramine. |
Candesartan | Candesartan The metabolism of Diphenhydramine can be decreased when combined with Candesartan. |
Cilostazol | Cilostazol The metabolism of Cilostazol can be decreased when combined with Diphenhydramine. |
Clopidogrel | Clopidogrel The metabolism of Diphenhydramine can be decreased when combined with Clopidogrel. |
Diphenoxylate | Diphenoxylate The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Diphenoxylate. |
Erythromycin and Sulfisoxazole | Erythromycin and Sulfisoxazole The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Erythromycin. |
Fenofibrate | Fenofibrate The metabolism of Diphenhydramine can be decreased when combined with Fenofibrate. |
Guanfacine | Guanfacine The risk or severity of adverse effects can be increased when Guanfacine is combined with Diphenhydramine. |
Magnesium Hydroxide | Magnesium Hydroxide The therapeutic efficacy of Magnesium hydroxide can be decreased when used in combination with Diphenhydramine. |
Magnesium Oxide | Magnesium Oxide The therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Diphenhydramine. |
Naratriptan | Naratriptan The risk or severity of adverse effects can be increased when Naratriptan is combined with Diphenhydramine. |
Paregoric | Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Diphenhydramine. |
Penbutolol | Penbutolol The metabolism of Acebutolol can be decreased when combined with Diphenhydramine. |
Pentazocine | Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Diphenhydramine. |
Polyethylene glycol-electrolyte solution (PEG-ES) | Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Diphenhydramine. |
Psyllium | Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Diphenhydramine. |
Ranitidine | Ranitidine The metabolism of Ranitidine can be decreased when combined with Diphenhydramine. |
Reserpine | Reserpine Reserpine may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Rizatriptan | Rizatriptan The risk or severity of adverse effects can be increased when Rizatriptan is combined with Diphenhydramine. |
Sumatriptan | Sumatriptan The risk or severity of adverse effects can be increased when Sumatriptan is combined with Diphenhydramine. |
Tacrolimus | Tacrolimus The risk or severity of QTc prolongation can be increased when Tacrolimus is combined with Diphenhydramine. |
Tizanidine | Tizanidine The risk or severity of adverse effects can be increased when Tizanidine is combined with Diphenhydramine. |
Zolmitriptan | Zolmitriptan The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Diphenhydramine. |
Famotidine Injection | Famotidine Injection The risk or severity of QTc prolongation can be increased when Famotidine is combined with Diphenhydramine. |
Fluconazole Injection | Fluconazole Injection The metabolism of Diphenhydramine can be decreased when combined with Fluconazole. |
Foscarnet Injection | Foscarnet Injection The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Diphenhydramine. |
Hydromorphone Injection | Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Diphenhydramine. |
Levofloxacin Injection | Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Levofloxacin. |
Meperidine Injection | Meperidine Injection The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Meperidine. |
Metoclopramide Injection | Metoclopramide Injection The risk or severity of sedation can be increased when Metoclopramide is combined with Diphenhydramine. |
Metronidazole Injection | Metronidazole Injection The metabolism of Diphenhydramine can be decreased when combined with Metronidazole. |
Morphine Injection | Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Diphenhydramine. |
Zidovudine Injection | Zidovudine Injection The metabolism of Diphenhydramine can be decreased when combined with Zidovudine. |
Altretamine | Altretamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Diphenhydramine. |
Cyclosporine | Cyclosporine The metabolism of Diphenhydramine can be decreased when combined with Cyclosporine. |
Ondansetron | Ondansetron The risk or severity of adverse effects can be increased when Ondansetron is combined with Diphenhydramine. |
Granisetron | Granisetron The risk or severity of adverse effects can be increased when Granisetron is combined with Diphenhydramine. |
Torsemide | Torsemide The metabolism of Diphenhydramine can be decreased when combined with Torasemide. |
Olanzapine | Olanzapine The risk or severity of adverse effects can be increased when Olanzapine is combined with Diphenhydramine. |
Alosetron | Alosetron The risk or severity of adverse effects can be increased when Alosetron is combined with Diphenhydramine. |
Dofetilide | Dofetilide The serum concentration of Dofetilide can be increased when it is combined with Diphenhydramine. |
Entacapone | Entacapone The risk or severity of adverse effects can be increased when Entacapone is combined with Diphenhydramine. |
Hydroxychloroquine | Hydroxychloroquine The metabolism of Diphenhydramine can be decreased when combined with Hydroxychloroquine. |
Meloxicam | Meloxicam The metabolism of Diphenhydramine can be decreased when combined with Meloxicam. |
Oxcarbazepine | Oxcarbazepine The risk or severity of adverse effects can be increased when Oxcarbazepine is combined with Diphenhydramine. |
Zaleplon | Zaleplon The risk or severity of adverse effects can be increased when Zaleplon is combined with Diphenhydramine. |
Anakinra | Anakinra The metabolism of Diphenhydramine can be increased when combined with Anakinra. |
Desloratadine | Desloratadine Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Desloratadine. |
Linezolid | Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Diphenhydramine. |
Rivastigmine | Rivastigmine The therapeutic efficacy of Diphenhydramine can be decreased when used in combination with Rivastigmine. |
Trimipramine | Trimipramine The metabolism of Diphenhydramine can be decreased when combined with Trimipramine. |
Etanercept Injection | Etanercept Injection The metabolism of Diphenhydramine can be increased when combined with Etanercept. |
Glycopyrrolate | Glycopyrrolate The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Glycopyrronium. |
Modafinil | Modafinil The metabolism of Diphenhydramine can be decreased when combined with Modafinil. |
Epinephrine Injection | Epinephrine Injection The serum concentration of Epinephrine can be increased when it is combined with Diphenhydramine. |
Escitalopram | Escitalopram The risk or severity of serotonin syndrome can be increased when Diphenhydramine is combined with Escitalopram. |
Zonisamide | Zonisamide The risk or severity of adverse effects can be increased when Zonisamide is combined with Diphenhydramine. |
Adalimumab Injection | Adalimumab Injection The metabolism of Diphenhydramine can be increased when combined with Adalimumab. |
Aripiprazole | Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Diphenhydramine. |
Atomoxetine | Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Diphenhydramine. |
Dexmethylphenidate | Dexmethylphenidate The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Dexmethylphenidate. |
Atazanavir | Atazanavir The risk or severity of QTc prolongation can be increased when Atazanavir is combined with Diphenhydramine. |
Almotriptan | Almotriptan The risk or severity of adverse effects can be increased when Almotriptan is combined with Diphenhydramine. |
Eletriptan | Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Diphenhydramine. |
Mefloquine | Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Diphenhydramine. |
Polyethylene Glycol 3350 | Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Diphenhydramine. |
Rosuvastatin | Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Diphenhydramine. |
Vardenafil | Vardenafil The risk or severity of QTc prolongation can be increased when Vardenafil is combined with Diphenhydramine. |
Alfuzosin | Alfuzosin The risk or severity of QTc prolongation can be increased when Alfuzosin is combined with Diphenhydramine. |
Aprepitant | Aprepitant The metabolism of Diphenhydramine can be decreased when combined with Aprepitant. |
Memantine | Memantine The serum concentration of Diphenhydramine can be increased when it is combined with Memantine. |
Tegaserod | Tegaserod The metabolism of Tegaserod can be decreased when combined with Diphenhydramine. |
Frovatriptan | Frovatriptan The risk or severity of adverse effects can be increased when Frovatriptan is combined with Diphenhydramine. |
Gemifloxacin | Gemifloxacin The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Gemifloxacin. |
Progesterone | Progesterone The metabolism of Diphenhydramine can be decreased when combined with Progesterone. |
Apomorphine Injection | Apomorphine Injection The risk or severity of adverse effects can be increased when Apomorphine is combined with Diphenhydramine. |
Infliximab Injection | Infliximab Injection The metabolism of Diphenhydramine can be increased when combined with Infliximab. |
Oxandrolone | Oxandrolone The metabolism of Diphenhydramine can be decreased when combined with Oxandrolone. |
Protriptyline | Protriptyline Protriptyline may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Duloxetine | Duloxetine The metabolism of Duloxetine can be decreased when combined with Diphenhydramine. |
Trospium | Trospium Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Trospium. |
Bosentan | Bosentan The metabolism of Diphenhydramine can be increased when combined with Bosentan. |
Cinacalcet | Cinacalcet The metabolism of Diphenhydramine can be decreased when combined with Cinacalcet. |
Erlotinib | Erlotinib The metabolism of Erlotinib can be decreased when combined with Diphenhydramine. |
Eszopiclone | Eszopiclone The risk or severity of CNS depression can be increased when Diphenhydramine is combined with Eszopiclone. |
Solifenacin | Solifenacin Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin. |
Voriconazole | Voriconazole The risk or severity of QTc prolongation can be increased when Voriconazole is combined with Diphenhydramine. |
Dextroamphetamine | Dextroamphetamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Diphenhydramine. |
Peginterferon Alfa-2b (PEG-Intron) | Peginterferon Alfa-2b (PEG-Intron) The metabolism of Diphenhydramine can be increased when combined with Peginterferon alfa-2b. |
Pramlintide Injection | Pramlintide Injection The risk or severity of reduced gastrointestinal motility can be increased when Pramlintide is combined with Diphenhydramine. |
Sodium Oxybate | Sodium Oxybate Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
Ibandronate | Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Diphenhydramine. |
Isocarboxazid | Isocarboxazid The risk or severity of adverse effects can be increased when Isocarboxazid is combined with Diphenhydramine. |
Ramelteon | Ramelteon The risk or severity of adverse effects can be increased when Ramelteon is combined with Diphenhydramine. |
Darifenacin | Darifenacin The metabolism of Diphenhydramine can be decreased when combined with Darifenacin. |
Fentanyl | Fentanyl The risk or severity of adverse effects can be increased when Fentanyl is combined with Diphenhydramine. |
Pregabalin | Pregabalin The therapeutic efficacy of Diphenhydramine can be increased when used in combination with Pregabalin. |
Tipranavir | Tipranavir The metabolism of Diphenhydramine can be decreased when combined with Tipranavir. |
Felbamate | Felbamate The metabolism of Diphenhydramine can be decreased when combined with Felbamate. |
Ranolazine | Ranolazine The serum concentration of Diphenhydramine can be increased when it is combined with Ranolazine. |
Abatacept Injection | Abatacept Injection The metabolism of Diphenhydramine can be increased when combined with Abatacept. |
Rasagiline | Rasagiline The risk or severity of adverse effects can be increased when Rasagiline is combined with Diphenhydramine. |
Imatinib | Imatinib The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Imatinib. |
Varenicline | Varenicline The excretion of Varenicline can be decreased when combined with Diphenhydramine. |
Gefitinib | Gefitinib The metabolism of Diphenhydramine can be decreased when combined with Gefitinib. |
Albuterol | Albuterol The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Diphenhydramine. |
Paliperidone | Paliperidone The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Paliperidone. |
Bortezomib | Bortezomib The risk or severity of QTc prolongation can be increased when Bortezomib is combined with Diphenhydramine. |
Clofarabine Injection | Clofarabine Injection The serum concentration of Clofarabine can be increased when it is combined with Diphenhydramine. |
Lubiprostone | Lubiprostone The therapeutic efficacy of Lubiprostone can be decreased when used in combination with Diphenhydramine. |
Oxaliplatin Injection | Oxaliplatin Injection The serum concentration of Oxaliplatin can be increased when it is combined with Diphenhydramine. |
Posaconazole | Posaconazole The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Posaconazole. |
Primaquine | Primaquine The metabolism of Primaquine can be decreased when combined with Diphenhydramine. |
Dimenhydrinate | Dimenhydrinate The risk or severity of adverse effects can be increased when Dimenhydrinate is combined with Diphenhydramine. |
Lisdexamfetamine | Lisdexamfetamine Lisdexamfetamine may decrease the sedative and stimulatory activities of Diphenhydramine. |
Nabilone | Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Vorinostat | Vorinostat The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Vorinostat. |
Sorafenib | Sorafenib The metabolism of Diphenhydramine can be decreased when combined with Sorafenib. |
Sunitinib | Sunitinib The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Sunitinib. |
Dronabinol | Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Lapatinib | Lapatinib The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Lapatinib. |
Levocetirizine | Levocetirizine The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Levocetirizine. |
Dasatinib | Dasatinib The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Dasatinib. |
Mexiletine | Mexiletine The metabolism of Mexiletine can be decreased when combined with Diphenhydramine. |
Armodafinil | Armodafinil The metabolism of Diphenhydramine can be decreased when combined with Armodafinil. |
Paclitaxel (with polyoxyethylated castor oil) Injection | Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Diphenhydramine. |
Temsirolimus | Temsirolimus The metabolism of Diphenhydramine can be decreased when combined with Temsirolimus. |
Nilotinib | Nilotinib The metabolism of Nilotinib can be decreased when combined with Diphenhydramine. |
Toremifene | Toremifene The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Toremifene. |
Bexarotene | Bexarotene The metabolism of Diphenhydramine can be decreased when combined with Bexarotene. |
Betaine | Betaine The therapeutic efficacy of Diphenhydramine can be decreased when used in combination with Glycine betaine. |
OnabotulinumtoxinA Injection | OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Botulinum toxin type A. |
RimabotulinumtoxinB Injection | RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Botulinum Toxin Type B. |
Etravirine | Etravirine The metabolism of Diphenhydramine can be decreased when combined with Etravirine. |
Arsenic Trioxide Injection | Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Arsenic trioxide. |
Desvenlafaxine | Desvenlafaxine The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Desvenlafaxine. |
Cevimeline | Cevimeline The metabolism of Cevimeline can be decreased when combined with Diphenhydramine. |
Nebivolol | Nebivolol The metabolism of Nebivolol can be decreased when combined with Diphenhydramine. |
Tretinoin | Tretinoin The metabolism of Diphenhydramine can be decreased when combined with Tretinoin. |
Flecainide | Flecainide The metabolism of Flecainide can be decreased when combined with Diphenhydramine. |
Certolizumab Injection | Certolizumab Injection The metabolism of Diphenhydramine can be increased when combined with Certolizumab pegol. |
Rufinamide | Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Diphenhydramine. |
Midazolam | Midazolam The risk or severity of adverse effects can be increased when Midazolam is combined with Diphenhydramine. |
Naltrexone Injection | Naltrexone Injection The risk or severity of adverse effects can be increased when Naltrexone is combined with Diphenhydramine. |
Milnacipran | Milnacipran The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Milnacipran. |
Sodium Phosphate | Sodium Phosphate The therapeutic efficacy of Sodium phosphate, monobasic can be decreased when used in combination with Diphenhydramine. |
Fesoterodine | Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Diphenhydramine. |
Degarelix Injection | Degarelix Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Degarelix. |
Betaxolol | Betaxolol The metabolism of Betaxolol can be decreased when combined with Diphenhydramine. |
Iloperidone | Iloperidone The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Iloperidone. |
Prasugrel | Prasugrel The metabolism of Prasugrel can be decreased when combined with Diphenhydramine. |
Lacosamide | Lacosamide The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Lacosamide. |
Everolimus | Everolimus The metabolism of Diphenhydramine can be decreased when combined with Everolimus. |
Dronedarone | Dronedarone The metabolism of Dronedarone can be decreased when combined with Diphenhydramine. |
AbobotulinumtoxinA Injection | AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Botulinum toxin type A. |
Palonosetron Injection | Palonosetron Injection The risk or severity of adverse effects can be increased when Palonosetron is combined with Diphenhydramine. |
Telavancin Injection | Telavancin Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Telavancin. |
Romidepsin Injection | Romidepsin Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Romidepsin. |
Tapentadol | Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Golimumab Injection | Golimumab Injection The metabolism of Diphenhydramine can be increased when combined with Golimumab. |
Pazopanib | Pazopanib The metabolism of Pazopanib can be decreased when combined with Diphenhydramine. |
Asenapine | Asenapine The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Asenapine. |
Vigabatrin | Vigabatrin The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Vigabatrin. |
Pitavastatin | Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Diphenhydramine. |
Oxymorphone | Oxymorphone The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Oxymorphone. |
Tocilizumab Injection | Tocilizumab Injection The metabolism of Diphenhydramine can be increased when combined with Tocilizumab. |
Dalfampridine | Dalfampridine The serum concentration of Dalfampridine can be increased when it is combined with Diphenhydramine. |
Eribulin Injection | Eribulin Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Eribulin. |
IncobotulinumtoxinA Injection | IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Botulinum toxin type A. |
Lurasidone | Lurasidone The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Lurasidone. |
Vilazodone | Vilazodone The metabolism of Vilazodone can be decreased when combined with Diphenhydramine. |
Terbutaline Injection | Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Diphenhydramine. |
Linagliptin | Linagliptin The serum concentration of Linagliptin can be increased when it is combined with Diphenhydramine. |
Rilpivirine | Rilpivirine The metabolism of Diphenhydramine can be decreased when combined with Rilpivirine. |
Cyclophosphamide Injection | Cyclophosphamide Injection The metabolism of Diphenhydramine can be decreased when combined with Cyclophosphamide. |
Abiraterone | Abiraterone The metabolism of Diphenhydramine can be decreased when combined with Abiraterone. |
Triptorelin Injection | Triptorelin Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Triptorelin. |
Ticagrelor | Ticagrelor The metabolism of Diphenhydramine can be decreased when combined with Ticagrelor. |
Vandetanib | Vandetanib The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Vandetanib. |
Clobazam | Clobazam The metabolism of Diphenhydramine can be decreased when combined with Clobazam. |
Vemurafenib | Vemurafenib The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Vemurafenib. |
Vismodegib | Vismodegib The metabolism of Diphenhydramine can be decreased when combined with Vismodegib. |
Crizotinib | Crizotinib The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Crizotinib. |
Cabergoline | Cabergoline The risk or severity of adverse effects can be increased when Cabergoline is combined with Diphenhydramine. |
Ezogabine | Ezogabine The risk or severity of adverse effects can be increased when Tiagabine is combined with Diphenhydramine. |
Enzalutamide | Enzalutamide The metabolism of Diphenhydramine can be increased when combined with Enzalutamide. |
Mirabegron | Mirabegron The risk or severity of urinary retention can be increased when Diphenhydramine is combined with Mirabegron. |
Regorafenib | Regorafenib The metabolism of Diphenhydramine can be decreased when combined with Regorafenib. |
Linaclotide | Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Diphenhydramine. |
Cabozantinib (thyroid cancer) | Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Diphenhydramine. |
Bedaquiline | Bedaquiline The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Bedaquiline. |
Alogliptin | Alogliptin The metabolism of Alogliptin can be decreased when combined with Diphenhydramine. |
Ponatinib | Ponatinib The metabolism of Ponatinib can be decreased when combined with Diphenhydramine. |
Pomalidomide | Pomalidomide The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Pomalidomide. |
Apixaban | Apixaban The metabolism of Apixaban can be decreased when combined with Diphenhydramine. |
Dabrafenib | Dabrafenib The metabolism of Diphenhydramine can be increased when combined with Dabrafenib. |
Ospemifene | Ospemifene The metabolism of Ospemifene can be decreased when combined with Diphenhydramine. |
Levomilnacipran | Levomilnacipran The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Levomilnacipran. |
Vortioxetine | Vortioxetine The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Vortioxetine. |
Perampanel | Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Ibrutinib | Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Diphenhydramine. |
Ketorolac Injection | Ketorolac Injection The metabolism of Diphenhydramine can be decreased when combined with Ketorolac. |
Dapagliflozin | Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Diphenhydramine. |
Apremilast | Apremilast The metabolism of Diphenhydramine can be increased when combined with Apremilast. |
Droxidopa | Droxidopa The therapeutic efficacy of Droxidopa can be increased when used in combination with Diphenhydramine. |
Ceritinib | Ceritinib The metabolism of Diphenhydramine can be decreased when combined with Ceritinib. |
Siltuximab Injection | Siltuximab Injection The metabolism of Diphenhydramine can be increased when combined with Siltuximab. |
Eslicarbazepine | Eslicarbazepine The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Eslicarbazepine. |
Testosterone Injection | Testosterone Injection The metabolism of Diphenhydramine can be decreased when combined with Testosterone. |
Oritavancin Injection | Oritavancin Injection The metabolism of Diphenhydramine can be decreased when combined with Oritavancin. |
Hydrocodone | Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Suvorexant | Suvorexant Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
Methamphetamine | Methamphetamine Metamfetamine may decrease the sedative and stimulatory activities of Diphenhydramine. |
Tasimelteon | Tasimelteon The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Tasimelteon. |
Secukinumab Injection | Secukinumab Injection The metabolism of Diphenhydramine can be increased when combined with Secukinumab. |
Risperidone Injection | Risperidone Injection The risk or severity of adverse effects can be increased when Risperidone is combined with Diphenhydramine. |
Lenvatinib | Lenvatinib The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Lenvatinib. |
Naloxegol | Naloxegol The metabolism of Diphenhydramine can be decreased when combined with Naloxegol. |
Panobinostat | Panobinostat The metabolism of Diphenhydramine can be decreased when combined with Panobinostat. |
Haloperidol Injection | Haloperidol Injection The risk or severity of QTc prolongation can be increased when Haloperidol is combined with Diphenhydramine. |
Ivabradine | Ivabradine The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Ivabradine. |
Flibanserin | Flibanserin The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Flibanserin. |
Rolapitant | Rolapitant The metabolism of Diphenhydramine can be decreased when combined with Rolapitant. |
Brexpiprazole | Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Diphenhydramine. |
Ziprasidone Injection | Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Ziprasidone. |
Cariprazine | Cariprazine The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Cariprazine. |
Eluxadoline | Eluxadoline The risk or severity of constipation can be increased when Diphenhydramine is combined with Eluxadoline. |
Trabectedin Injection | Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Diphenhydramine. |
Lesinurad | Lesinurad The metabolism of Lesinurad can be decreased when combined with Diphenhydramine. |
Brivaracetam Injection | Brivaracetam Injection The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Brivaracetam. |
Cobicistat | Cobicistat The metabolism of Diphenhydramine can be decreased when combined with Cobicistat. |
Midodrine | Midodrine The risk or severity of Tachycardia can be increased when Midodrine is combined with Diphenhydramine. |
Pimavanserin | Pimavanserin The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Pimavanserin. |
Rucaparib | Rucaparib The metabolism of Diphenhydramine can be decreased when combined with Rucaparib. |
Ribociclib | Ribociclib The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Ribociclib. |
Doxepin (Insomnia) | Doxepin (Insomnia) Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Doxepin. |
Plecanatide | Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Diphenhydramine. |
Deutetrabenazine | Deutetrabenazine The risk or severity of sedation and somnolence can be increased when Diphenhydramine is combined with Deutetrabenazine. |
Valbenazine | Valbenazine The metabolism of Valbenazine can be decreased when combined with Diphenhydramine. |
Safinamide | Safinamide The risk or severity of adverse effects can be increased when Safinamide is combined with Diphenhydramine. |
Midostaurin | Midostaurin The metabolism of Diphenhydramine can be decreased when combined with Midostaurin. |
Enasidenib | Enasidenib The metabolism of Diphenhydramine can be decreased when combined with Enasidenib. |
Delafloxacin | Delafloxacin The risk or severity of QTc prolongation can be increased when Delafloxacin is combined with Diphenhydramine. |
Letermovir | Letermovir The metabolism of Letermovir can be decreased when combined with Diphenhydramine. |
Tetrabenazine | Tetrabenazine The risk or severity of sedation and somnolence can be increased when Diphenhydramine is combined with Tetrabenazine. |
Buprenorphine Injection | Buprenorphine Injection Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
Apalutamide | Apalutamide The metabolism of Diphenhydramine can be increased when combined with Apalutamide. |
Avatrombopag | Avatrombopag The metabolism of Diphenhydramine can be increased when combined with Avatrombopag. |
Lofexidine | Lofexidine The therapeutic efficacy of Diphenhydramine can be increased when used in combination with Lofexidine. |
Eliglustat | Eliglustat The risk or severity of QTc prolongation can be increased when Eliglustat is combined with Diphenhydramine. |
Encorafenib | Encorafenib The metabolism of Encorafenib can be decreased when combined with Diphenhydramine. |
Ivosidenib | Ivosidenib The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Ivosidenib. |
Elagolix | Elagolix The metabolism of Elagolix can be decreased when combined with Diphenhydramine. |
Tafenoquine | Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Diphenhydramine. |
Cannabidiol | Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Diphenhydramine. |
Dacomitinib | Dacomitinib The metabolism of Diphenhydramine can be decreased when combined with Dacomitinib. |
Stiripentol | Stiripentol The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Stiripentol. |
Gilteritinib | Gilteritinib The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Gilteritinib. |
Glasdegib | Glasdegib The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Glasdegib. |
Rifamycin | Rifamycin The metabolism of Diphenhydramine can be decreased when combined with Rifamycin. |
Prucalopride | Prucalopride The therapeutic efficacy of Prucalopride can be decreased when used in combination with Diphenhydramine. |
Magnesium Citrate | Magnesium Citrate The therapeutic efficacy of Magnesium citrate can be decreased when used in combination with Diphenhydramine. |
Emapalumab-lzsg Injection | Emapalumab-lzsg Injection The metabolism of Diphenhydramine can be increased when combined with Emapalumab. |
Siponimod | Siponimod The metabolism of Siponimod can be decreased when combined with Diphenhydramine. |
Erdafitinib | Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Diphenhydramine. |
Alpelisib | Alpelisib The serum concentration of Diphenhydramine can be decreased when it is combined with Alpelisib. |
Brexanolone Injection | Brexanolone Injection The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Brexanolone. |
Solriamfetol | Solriamfetol The risk or severity of Tachycardia can be increased when Solriamfetol is combined with Diphenhydramine. |
Triclabendazole | Triclabendazole The metabolism of Diphenhydramine can be decreased when combined with Triclabendazole. |
Entrectinib | Entrectinib The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Entrectinib. |
Istradefylline | Istradefylline The metabolism of Istradefylline can be decreased when combined with Diphenhydramine. |
Pitolisant | Pitolisant The therapeutic efficacy of Pitolisant can be decreased when used in combination with Diphenhydramine. |
Fedratinib | Fedratinib The metabolism of Diphenhydramine can be decreased when combined with Fedratinib. |
Lefamulin | Lefamulin Lefamulin may increase the QTc-prolonging activities of Diphenhydramine. |
Phenytoin Injection | Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Diphenhydramine. |
Fosphenytoin Injection | Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Diphenhydramine. |
Voxelotor | Voxelotor The metabolism of Voxelotor can be decreased when combined with Diphenhydramine. |
Avapritinib | Avapritinib The metabolism of Avapritinib can be decreased when combined with Diphenhydramine. |
Lumateperone | Lumateperone The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Lumateperone. |
Lasmiditan | Lasmiditan The risk or severity of serotonin syndrome can be increased when Diphenhydramine is combined with Lasmiditan. |
Selumetinib | Selumetinib The metabolism of Selumetinib can be decreased when combined with Diphenhydramine. |
Lemborexant | Lemborexant Lemborexant may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Daratumumab and Hyaluronidase-fihj Injection | Daratumumab and Hyaluronidase-fihj Injection The therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Diphenhydramine. |
Fenfluramine | Fenfluramine The risk or severity of serotonin syndrome can be increased when Fenfluramine is combined with Diphenhydramine. |
Fostemsavir | Fostemsavir The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Fostemsavir. |
Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf Injection | Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf Injection The therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Diphenhydramine. |
Octreotide | Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Diphenhydramine. |
Pralsetinib | Pralsetinib The metabolism of Diphenhydramine can be decreased when combined with Pralsetinib. |
Satralizumab-mwge Injection | Satralizumab-mwge Injection The serum concentration of Diphenhydramine can be decreased when it is combined with Satralizumab. |
Relugolix | Relugolix The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Relugolix. |
Viloxazine | Viloxazine The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Viloxazine. |
Theophylline | Theophylline The metabolism of Theophylline can be decreased when combined with Diphenhydramine. |
Indomethacin | Indomethacin The metabolism of Diphenhydramine can be decreased when combined with Indomethacin. |
Mefenamic Acid | Mefenamic Acid The metabolism of Diphenhydramine can be decreased when combined with Mefenamic acid. |
Trazodone | Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Diphenhydramine. |
Hydroxyurea | Hydroxyurea The metabolism of Diphenhydramine can be decreased when combined with Hydroxyurea. |
Floxuridine | Floxuridine The metabolism of Diphenhydramine can be decreased when combined with Floxuridine. |
Phenobarbital | Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Diphenhydramine. |
Metaxalone | Metaxalone The risk or severity of adverse effects can be increased when Metaxalone is combined with Diphenhydramine. |
Levorphanol | Levorphanol The risk or severity of adverse effects can be increased when Levorphanol is combined with Diphenhydramine. |
Primidone | Primidone The risk or severity of adverse effects can be increased when Primidone is combined with Diphenhydramine. |
Methsuximide | Methsuximide The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Methsuximide. |
Diethylpropion | Diethylpropion Diethylpropion may decrease the sedative and stimulatory activities of Diphenhydramine. |
Chlorpromazine | Chlorpromazine The metabolism of Diphenhydramine can be decreased when combined with Chlorpromazine. |
Diazepam | Diazepam The risk or severity of adverse effects can be increased when Diazepam is combined with Diphenhydramine. |
Oxazepam | Oxazepam The risk or severity of adverse effects can be increased when Oxazepam is combined with Diphenhydramine. |
Flurazepam | Flurazepam The risk or severity of adverse effects can be increased when Flurazepam is combined with Diphenhydramine. |
Clorazepate | Clorazepate The risk or severity of adverse effects can be increased when Clorazepic acid is combined with Diphenhydramine. |
Lorazepam | Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Diphenhydramine. |
Amantadine | Amantadine The serum concentration of Diphenhydramine can be increased when it is combined with Amantadine. |
Meprobamate | Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Diphenhydramine. |
Chlordiazepoxide | Chlordiazepoxide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Diphenhydramine. |
Bromocriptine | Bromocriptine The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Bromocriptine. |
Metaproterenol | Metaproterenol The risk or severity of Tachycardia can be increased when Orciprenaline is combined with Diphenhydramine. |
Tranylcypromine | Tranylcypromine The risk or severity of adverse effects can be increased when Tranylcypromine is combined with Diphenhydramine. |
Phenelzine | Phenelzine The risk or severity of adverse effects can be increased when Phenelzine is combined with Diphenhydramine. |
Procarbazine | Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Diphenhydramine. |
Ergoloid Mesylates | Ergoloid Mesylates The risk or severity of adverse effects can be increased when Ergoloid mesylate is combined with Diphenhydramine. |
Minocycline | Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Prochlorperazine | Prochlorperazine The risk or severity of adverse effects can be increased when Prochlorperazine is combined with Diphenhydramine. |
Thioridazine | Thioridazine The metabolism of Diphenhydramine can be decreased when combined with Thioridazine. |
Trifluoperazine | Trifluoperazine The risk or severity of adverse effects can be increased when Trifluoperazine is combined with Diphenhydramine. |
Dapsone | Dapsone The metabolism of Diphenhydramine can be decreased when combined with Dapsone. |
Sulfadiazine | Sulfadiazine The metabolism of Diphenhydramine can be decreased when combined with Sulfadiazine. |
Oxycodone | Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Diphenhydramine. |
Methadone | Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Diphenhydramine. |
Oxybutynin | Oxybutynin Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin. |
Benztropine | Benztropine The metabolism of Benzatropine can be decreased when combined with Diphenhydramine. |
Maprotiline | Maprotiline The risk or severity of adverse effects can be increased when Maprotiline is combined with Diphenhydramine. |
Trihexyphenidyl | Trihexyphenidyl Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl. |
Orphenadrine | Orphenadrine Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
Perphenazine | Perphenazine The risk or severity of adverse effects can be increased when Perphenazine is combined with Diphenhydramine. |
Fluphenazine | Fluphenazine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Diphenhydramine. |
Phentermine | Phentermine Phentermine may decrease the sedative and stimulatory activities of Diphenhydramine. |
Amoxapine | Amoxapine The metabolism of Diphenhydramine can be decreased when combined with Amoxapine. |
Doxorubicin | Doxorubicin The metabolism of Diphenhydramine can be decreased when combined with Doxorubicin. |
Mechlorethamine | Mechlorethamine The therapeutic efficacy of Diphenhydramine can be decreased when used in combination with Mechlorethamine. |
Pyridostigmine | Pyridostigmine The therapeutic efficacy of Diphenhydramine can be decreased when used in combination with Pyridostigmine. |
Carbamazepine | Carbamazepine Carbamazepine may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Molindone | Molindone The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Molindone. |
Clonidine | Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Diphenhydramine. |
Prazosin | Prazosin The serum concentration of Prazosin can be increased when it is combined with Diphenhydramine. |
Cimetidine | Cimetidine The metabolism of Cimetidine can be decreased when combined with Diphenhydramine. |
Warfarin | Warfarin The metabolism of Diphenhydramine can be decreased when combined with Warfarin. |
Clonazepam | Clonazepam The risk or severity of adverse effects can be increased when Clonazepam is combined with Diphenhydramine. |
Loperamide | Loperamide The metabolism of Loperamide can be decreased when combined with Diphenhydramine. |
Promethazine | Promethazine The metabolism of Diphenhydramine can be decreased when combined with Promethazine. |
Digoxin | Digoxin The risk or severity of QTc prolongation can be increased when Digoxin is combined with Diphenhydramine. |
Loxapine | Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Diphenhydramine. |
Chloroquine | Chloroquine The metabolism of Diphenhydramine can be decreased when combined with Chloroquine. |
Quinine | Quinine The metabolism of Quinine can be decreased when combined with Diphenhydramine. |
Ethosuximide | Ethosuximide The risk or severity of adverse effects can be increased when Ethosuximide is combined with Diphenhydramine. |
Lactulose | Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Diphenhydramine. |
Sulfinpyrazone | Sulfinpyrazone The metabolism of Diphenhydramine can be decreased when combined with Sulfinpyrazone. |
Chlorothiazide | Chlorothiazide The serum concentration of Chlorothiazide can be increased when it is combined with Diphenhydramine. |
Chlorthalidone | Chlorthalidone The serum concentration of Chlorthalidone can be increased when it is combined with Diphenhydramine. |
Metolazone | Metolazone The serum concentration of Metolazone can be increased when it is combined with Diphenhydramine. |
Secobarbital | Secobarbital The risk or severity of adverse effects can be increased when Secobarbital is combined with Diphenhydramine. |
Desipramine | Desipramine The metabolism of Desipramine can be decreased when combined with Diphenhydramine. |
Amitriptyline | Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Diphenhydramine. |
Imipramine | Imipramine The metabolism of Imipramine can be decreased when combined with Diphenhydramine. |
Probenecid | Probenecid The metabolism of Diphenhydramine can be decreased when combined with Probenecid. |
Quinidine | Quinidine The metabolism of Diphenhydramine can be decreased when combined with Quinidine. |
Procainamide | Procainamide The metabolism of Procainamide can be decreased when combined with Diphenhydramine. |
Isoniazid | Isoniazid The metabolism of Diphenhydramine can be decreased when combined with Isoniazid. |
Disopyramide | Disopyramide The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Disopyramide. |
Valproic Acid | Valproic Acid Valproic acid may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Tamoxifen | Tamoxifen The metabolism of Diphenhydramine can be decreased when combined with Tamoxifen. |
Butabarbital | Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Diphenhydramine. |
Methimazole | Methimazole The metabolism of Diphenhydramine can be decreased when combined with Methimazole. |
Chlorpropamide | Chlorpropamide The metabolism of Diphenhydramine can be decreased when combined with Chlorpropamide. |
Glucagon Injection | Glucagon Injection Diphenhydramine may increase the gastrointestinal motility reducing activities of Glucagon. |
Tolbutamide | Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Diphenhydramine. |
Tolazamide | Tolazamide The metabolism of Diphenhydramine can be decreased when combined with Tolazamide. |
Cyclobenzaprine | Cyclobenzaprine The risk or severity of CNS depression can be increased when Cyclobenzaprine is combined with Diphenhydramine. |
Niacin | Niacin The metabolism of Diphenhydramine can be decreased when combined with Niacin. |
Baclofen | Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Diphenhydramine. |
Doxylamine | Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Cyproheptadine | Cyproheptadine Cyproheptadine may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Clemastine | Clemastine The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Clemastine. |
Chlorpheniramine | Chlorpheniramine The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Chlorpheniramine. |
Brompheniramine | Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Diphenhydramine. |
Meclizine | Meclizine The risk or severity of adverse effects can be increased when Meclizine is combined with Diphenhydramine. |
Methyclothiazide | Methyclothiazide The serum concentration of Methyclothiazide can be increased when it is combined with Diphenhydramine. |
Hydrochlorothiazide | Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Hydrochlorothiazide. |
Dantrolene | Dantrolene The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Dantrolene. |
Chlorzoxazone | Chlorzoxazone The risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Diphenhydramine. |
Carisoprodol | Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Diphenhydramine. |
Methocarbamol | Methocarbamol The risk or severity of adverse effects can be increased when Methocarbamol is combined with Diphenhydramine. |
Disulfiram | Disulfiram The risk or severity of QTc prolongation can be increased when Disulfiram is combined with Diphenhydramine. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The metabolism of Propranolol can be decreased when combined with Diphenhydramine. |
Nortriptyline | Nortriptyline The metabolism of Diphenhydramine can be decreased when combined with Nortriptyline. |
Nadolol | Nadolol The metabolism of Nadolol can be decreased when combined with Diphenhydramine. |
Butorphanol Injection | Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Diphenhydramine. |
Nalbuphine Injection | Nalbuphine Injection The risk or severity of adverse effects can be increased when Nalbuphine is combined with Diphenhydramine. |
Oxytocin Injection | Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Diphenhydramine. |
Trimethobenzamide | Trimethobenzamide Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine. |
Flavoxate | Flavoxate Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Flavoxate. |
Papaverine | Papaverine The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Papaverine. |
Fluorouracil Injection | Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Fluorouracil. |
Acetazolamide | Acetazolamide The risk or severity of adverse effects can be increased when Acetazolamide is combined with Diphenhydramine. |
Ketoconazole | Ketoconazole The metabolism of Diphenhydramine can be decreased when combined with Ketoconazole. |
Pyrantel | Pyrantel The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Pyrantel. |
Thiotepa Injection | Thiotepa Injection The therapeutic efficacy of Diphenhydramine can be decreased when used in combination with Thiotepa. |
Isoxsuprine | Isoxsuprine The risk or severity of Tachycardia can be increased when Diphenhydramine is combined with Isoxsuprine. |
Vinblastine | Vinblastine The metabolism of Diphenhydramine can be decreased when combined with Vinblastine. |
Metoprolol | Metoprolol The metabolism of Diphenhydramine can be decreased when combined with Metoprolol. |
Hydroxyzine | Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Diphenhydramine. |
Thiothixene | Thiothixene The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Thiothixene. |
Alprazolam | Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Diphenhydramine. |
Temazepam | Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Diphenhydramine. |
Triazolam | Triazolam The risk or severity of adverse effects can be increased when Triazolam is combined with Diphenhydramine. |
Dicyclomine | Dicyclomine Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine. |
Hyoscyamine | Hyoscyamine Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine. |
Propantheline | Propantheline Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Propantheline. |
Trimethoprim | Trimethoprim The metabolism of Diphenhydramine can be decreased when combined with Trimethoprim. |
Diltiazem | Diltiazem The metabolism of Diltiazem can be decreased when combined with Diphenhydramine. |
Nifedipine | Nifedipine The metabolism of Nifedipine can be decreased when combined with Diphenhydramine. |
Timolol | Timolol The metabolism of Timolol can be decreased when combined with Diphenhydramine. |
Verapamil | Verapamil The metabolism of Diphenhydramine can be decreased when combined with Verapamil. |
Atenolol | Atenolol The metabolism of Atenolol can be decreased when combined with Diphenhydramine. |
Pindolol | Pindolol The risk or severity of adverse effects can be increased when Pindolol is combined with Diphenhydramine. |
Cisplatin Injection | Cisplatin Injection The serum concentration of Diphenhydramine can be increased when it is combined with Cisplatin. |
Piroxicam | Piroxicam The metabolism of Diphenhydramine can be decreased when combined with Piroxicam. |
Glyburide | Glyburide The metabolism of Diphenhydramine can be decreased when combined with Glyburide. |
Glipizide | Glipizide The metabolism of Diphenhydramine can be decreased when combined with Glipizide. |
Indapamide | Indapamide The risk or severity of QTc prolongation can be increased when Indapamide is combined with Diphenhydramine. |
Pentamidine Injection | Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Diphenhydramine. |
Labetalol | Labetalol The metabolism of Diphenhydramine can be decreased when combined with Labetalol. |
Leuprolide Injection | Leuprolide Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Leuprolide. |
Gemfibrozil | Gemfibrozil The metabolism of Diphenhydramine can be decreased when combined with Gemfibrozil. |
Guanabenz | Guanabenz The risk or severity of Tachycardia can be increased when Guanabenz is combined with Diphenhydramine. |
Pimozide | Pimozide The metabolism of Pimozide can be decreased when combined with Diphenhydramine. |
Flurbiprofen | Flurbiprofen The metabolism of Diphenhydramine can be decreased when combined with Flurbiprofen. |
Amiodarone | Amiodarone The metabolism of Diphenhydramine can be decreased when combined with Amiodarone. |
Buspirone | Buspirone The metabolism of Buspirone can be decreased when combined with Diphenhydramine. |
Lovastatin | Lovastatin The metabolism of Diphenhydramine can be decreased when combined with Lovastatin. |
Ciprofloxacin | Ciprofloxacin The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Ciprofloxacin. |
Diclofenac | Diclofenac The metabolism of Diphenhydramine can be decreased when combined with Diclofenac. |
Fluoxetine | Fluoxetine The serum concentration of Diphenhydramine can be increased when it is combined with Fluoxetine. |
Nimodipine | Nimodipine The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Nimodipine. |
Clozapine | Clozapine The metabolism of Diphenhydramine can be decreased when combined with Clozapine. |
Estazolam | Estazolam The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Estazolam. |
Idarubicin | Idarubicin The metabolism of Idarubicin can be decreased when combined with Diphenhydramine. |
Ofloxacin | Ofloxacin The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Ofloxacin. |
Clarithromycin | Clarithromycin The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Clarithromycin. |
Etodolac | Etodolac The metabolism of Diphenhydramine can be decreased when combined with Etodolac. |
Felodipine | Felodipine The metabolism of Diphenhydramine can be decreased when combined with Felodipine. |
Nabumetone | Nabumetone The metabolism of Diphenhydramine can be decreased when combined with Nabumetone. |
Simvastatin | Simvastatin The metabolism of Diphenhydramine can be decreased when combined with Simvastatin. |
Teniposide Injection | Teniposide Injection The metabolism of Diphenhydramine can be decreased when combined with Teniposide. |
Itraconazole | Itraconazole The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Itraconazole. |
Atovaquone | Atovaquone The metabolism of Diphenhydramine can be decreased when combined with Atovaquone. |
Sotalol | Sotalol The metabolism of Sotalol can be decreased when combined with Diphenhydramine. |
Zolpidem | Zolpidem Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
Doxazosin | Doxazosin The metabolism of Doxazosin can be decreased when combined with Diphenhydramine. |
Isradipine | Isradipine The risk or severity of QTc prolongation can be increased when Isradipine is combined with Diphenhydramine. |
Omeprazole | Omeprazole The metabolism of Diphenhydramine can be decreased when combined with Omeprazole. |
Cisapride | Cisapride The metabolism of Diphenhydramine can be decreased when combined with Cisapride. |
Gabapentin | Gabapentin The risk or severity of adverse effects can be increased when Gabapentin is combined with Diphenhydramine. |
Fluvastatin | Fluvastatin The metabolism of Diphenhydramine can be decreased when combined with Fluvastatin. |
Venlafaxine | Venlafaxine The metabolism of Diphenhydramine can be decreased when combined with Venlafaxine. |
Nizatidine | Nizatidine The therapeutic efficacy of Diphenhydramine can be decreased when used in combination with Nizatidine. |
Fluvoxamine | Fluvoxamine The metabolism of Fluvoxamine can be decreased when combined with Diphenhydramine. |
Nefazodone | Nefazodone The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Nefazodone. |
Lamotrigine | Lamotrigine The risk or severity of adverse effects can be increased when Lamotrigine is combined with Diphenhydramine. |
Losartan | Losartan The risk or severity of QTc prolongation can be increased when Losartan is combined with Diphenhydramine. |
Tramadol | Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Diphenhydramine. |
Vinorelbine Injection | Vinorelbine Injection The metabolism of Diphenhydramine can be decreased when combined with Vinorelbine. |
Moexipril | Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Diphenhydramine. |
Lansoprazole | Lansoprazole The metabolism of Diphenhydramine can be decreased when combined with Lansoprazole. |
Ifosfamide Injection | Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Diphenhydramine. |
Nicardipine | Nicardipine The metabolism of Diphenhydramine can be decreased when combined with Nicardipine. |
Bupropion | Bupropion The metabolism of Diphenhydramine can be decreased when combined with Bupropion. |
Ticlopidine | Ticlopidine The metabolism of Diphenhydramine can be decreased when combined with Ticlopidine. |
Saquinavir | Saquinavir The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Saquinavir. |
Metformin | Metformin The serum concentration of Metformin can be increased when it is combined with Diphenhydramine. |
Lamivudine | Lamivudine The serum concentration of Lamivudine can be increased when it is combined with Diphenhydramine. |
Riluzole | Riluzole The risk or severity of adverse effects can be increased when Riluzole is combined with Diphenhydramine. |
Glimepiride | Glimepiride The metabolism of Diphenhydramine can be decreased when combined with Glimepiride. |
Ritonavir | Ritonavir The metabolism of Diphenhydramine can be decreased when combined with Ritonavir. |
Clomipramine | Clomipramine The metabolism of Diphenhydramine can be decreased when combined with Clomipramine. |
Zafirlukast | Zafirlukast The metabolism of Diphenhydramine can be decreased when combined with Zafirlukast. |
Mirtazapine | Mirtazapine Diphenhydramine may increase the serotonergic activities of Mirtazapine. |
Topiramate | Topiramate The risk or severity of hyperthermia and oligohydrosis can be increased when Diphenhydramine is combined with Topiramate. |
Zileuton | Zileuton The metabolism of Diphenhydramine can be decreased when combined with Zileuton. |
Valsartan | Valsartan The metabolism of Diphenhydramine can be decreased when combined with Valsartan. |
Pramipexole | Pramipexole Diphenhydramine may increase the sedative activities of Pramipexole. |
Donepezil | Donepezil The therapeutic efficacy of Diphenhydramine can be decreased when used in combination with Donepezil. |
Nelfinavir | Nelfinavir The metabolism of Diphenhydramine can be decreased when combined with Nelfinavir. |
Azithromycin | Azithromycin The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Azithromycin. |
Loratadine | Loratadine Diphenhydramine may increase the anticholinergic activities of Loratadine. |
Carvedilol | Carvedilol The metabolism of Carvedilol can be decreased when combined with Diphenhydramine. |
Nilutamide | Nilutamide The metabolism of Diphenhydramine can be decreased when combined with Nilutamide. |
Selegiline | Selegiline The risk or severity of adverse effects can be increased when Selegiline is combined with Diphenhydramine. |
Bicalutamide | Bicalutamide The metabolism of Diphenhydramine can be decreased when combined with Bicalutamide. |
Sertraline | Sertraline The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Sertraline. |
Propafenone | Propafenone The metabolism of Diphenhydramine can be decreased when combined with Propafenone. |
Irbesartan | Irbesartan The metabolism of Diphenhydramine can be decreased when combined with Irbesartan. |
Tamsulosin | Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Diphenhydramine. |
Ropinirole | Ropinirole Diphenhydramine may increase the sedative activities of Ropinirole. |
Quetiapine | Quetiapine The metabolism of Quetiapine can be decreased when combined with Diphenhydramine. |
Cetirizine | Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Diphenhydramine. |
Paroxetine | Paroxetine The metabolism of Diphenhydramine can be decreased when combined with Paroxetine. |
Tolcapone | Tolcapone The risk or severity of adverse effects can be increased when Tolcapone is combined with Diphenhydramine. |
Citalopram | Citalopram The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Citalopram. |
Capecitabine | Capecitabine The metabolism of Diphenhydramine can be decreased when combined with Capecitabine. |
Efavirenz | Efavirenz The risk or severity of adverse effects can be increased when Efavirenz is combined with Diphenhydramine. |
Sildenafil | Sildenafil The metabolism of Sildenafil can be decreased when combined with Diphenhydramine. |
Celecoxib | Celecoxib The metabolism of Diphenhydramine can be decreased when combined with Celecoxib. |
Rosiglitazone | Rosiglitazone The metabolism of Diphenhydramine can be decreased when combined with Rosiglitazone. |
Tolterodine | Tolterodine The metabolism of Tolterodine can be decreased when combined with Diphenhydramine. |
Thalidomide | Thalidomide Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
Nateglinide | Nateglinide The metabolism of Nateglinide can be decreased when combined with Diphenhydramine. |
Galantamine | Galantamine The risk or severity of QTc prolongation can be increased when Galantamine is combined with Diphenhydramine. |
Levetiracetam | Levetiracetam The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Levetiracetam. |
Rabeprazole | Rabeprazole The metabolism of Diphenhydramine can be decreased when combined with Rabeprazole. |
Terbinafine | Terbinafine The metabolism of Diphenhydramine can be decreased when combined with Terbinafine. |
* This branded product is no longer on the market. Generic alternatives may be available.
** These products are not currently approved by the FDA for safety, effectiveness, and quality. Federal law generally requires that prescription drugs in the U.S. be shown to be both safe and effective prior to marketing. Please see the FDA website for more information on unapproved drugs (http://www.fda.gov/AboutFDA/Transparency/Basics/ucm213030.htm ) and the approval process (http://www.fda.gov/Drugs/ResourcesForYou/Consumers/ucm054420.htm ).
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists