Etanercept Injection

Generic name: Pronounced as (et a ner' set)
Brand names
  • Enbrel®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 07/15/2018

Using etanercept injection may decrease your ability to fight infection and increase the risk that you will get a serious infection, including severe viral, bacterial, or fungal infections that spread throughout the body. These infections may need to be treated in a hospital and may cause death. Tell your doctor if you often get any type of infection or if you think you may have any type of infection now. This includes minor infections (such as open cuts or sores), infections that come and go (such as cold sores) and chronic infections that do not go away. Also tell your doctor if you have or have ever had diabetes, human immunodeficiency virus (HIV) , acquired immunodeficiency syndrome (AIDS), or any other condition that affects your immune system. You should also tell your doctor if you live or have ever lived in areas such as the Ohio and Mississippi river valleys where severe fungal infections are more common. Ask your doctor if you do not know if these infections are common in your area. Also tell your doctor if you are taking medications that decrease the activity of the immune system such as the following: abatacept (Orencia); anakinra (Kineret); azathioprine (Imuran); steroids including dexamethasone, methylprednisolone (Medrol), prednisolone (Prelone) and prednisone; or methotrexate (Rheumatrex).

Your doctor will monitor you for signs of infection during and shortly after your treatment. If you have any of the following symptoms before you begin your treatment or if you experience any of the following symptoms during or shortly after your treatment, call your doctor immediately: weakness; sweating; difficulty breathing; sore throat; cough; coughing up bloody mucus; fever; weight loss; extreme tiredness; diarrhea; stomach pain; flu-like symptoms; warm, red, or painful skin; or other signs of infection.

You may be infected with tuberculosis (TB, a type of lung infection) or hepatitis B (a type of liver disease) but do not have any symptoms of the disease. In this case, etanercept injection may increase the risk that your infection will become more serious and you will develop symptoms. Your doctor will perform a skin test to see if you have an inactive TB infection and may order blood tests to see if you have an inactive hepatitis B infection. If necessary, your doctor will give you medicine to treat this infection before you begin using etanercept injection. Tell your doctor if you have or have ever had TB, if you have lived in a country where TB is common, or if you have been around someone who has TB. If you have any of the following symptoms of TB, or if you develop any of these symptoms during your treatment, call your doctor immediately: cough, weight loss, loss of muscle tone, or fever. Also call your doctor immediately if you have any of these symptoms of hepatitis B or if you develop any of these symptoms during or after your treatment: excessive tiredness, yellowing of the skin or eyes, loss of appetite, nausea or vomiting, muscle aches, dark urine, clay-colored bowel movements, fever, chills, stomach pain, or rash.

Some children and teenagers who received etanercept injection and similar medications developed severe or life-threatening cancers including lymphoma (cancer that begins in the cells that fight infection). If your child develops any of these symptoms during his treatment, call his doctor immediately: unexplained weight loss; swollen glands in the neck, underarms, or groin; or easy bruising or bleeding. Talk to your child's doctor about the risks of giving etanercept injection to your child.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with etanercept injection and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.

Talk to your doctor about the risks of using etanercept injection.

Etanercept is used alone or with other medications to relieve the symptoms of certain autoimmune disorders (conditions in which the immune system attacks healthy parts of the body and causes pain, swelling, and damage) including:

  • rheumatoid arthritis (condition in which the body attacks its own joints, causing pain, swelling, and loss of function) in adults,

  • psoriatic arthritis (condition that causes joint pain and swelling and scales on the skin) in adults,

  • juvenile idiopathic arthritis (JIA; a condition that affects children in which the body attacks its own joints, causing pain, swelling, loss of function, and delays in growth and development) in children 2 years of age and older,

  • ankylosing spondylitis (a condition in which the body attacks the joints of the spine and other areas causing pain and joint damage),

  • chronic plaque psoriasis (a skin disease in which red, scaly patches form on some areas of the body) in adults and children 4 years of age and older whose psoriasis is too severe to be treated by topical medications alone.

Etanercept is in a class of medications called tumor-necrosis factor (TNF) inhibitors. It works by blocking the action of TNF, a substance in the body that causes inflammation

Etanercept injection comes as a solution (liquid) in a prefilled syringe and an automatic injection device, and as a powder to be mixed with a provided liquid. Etanercept is injected subcutaneously (under the skin). It is usually injected once a week. When etanercept injection is used to treat chronic plaque psoriasis, it may be injected twice a week during the first 3 months of treatment and then once a week after the first 3 months. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use etanercept exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

You will receive your first dose of etanercept injection in a doctor's office. After that, you can inject the medication yourself at home or have a friend or relative perform the injections. Ask your doctor or pharmacist to show you or the person who will be performing the injections how to inject etanercept. Read the written instructions that come with etanercept injection before you inject the medication.

Vials of etanercept injection may contain enough medication for more than one dose. If there is enough medication left in the vial for a complete dose, place the vial in the refrigerator as soon as possible, but no later than 4 hours after you mix it. You may store the vial of etanercept injection for up to 14 days after you mix it if there is enough medication remaining for a complete dose. However, you should not combine the contents of two or more vials of etanercept injection to make a complete dose. You also should not mix any other medications with etanercept injection.

If your medication comes in a prefilled syringe or automatic injection device, use each syringe or device only once and inject all the solution in the syringe or device. Even if there is still some solution left in the syringe or device, do not use it again. Dispose of used needles, syringes, and devices in a puncture-resistant container. Talk to your doctor or pharmacist about how to dispose of the puncture-resistant container.

If you are using a prefilled syringe, an automatic injection device, or a vial that has been refrigerated, place the syringe, device, or vial on a flat surface and allow it warm to room temperature for 15-30 minutes before you are ready to inject the medication. Do not try to warm the medication by heating it in a microwave, placing it in hot water, or through any other method.

Do not shake a syringe, automatic injection device, or vial that contains etanercept. Be careful not to drop the device onto a hard surface because this may damage the device, syringe, or needle.

Always look at etanercept solution before injecting it. Check that the expiration date has not passed and that the liquid is clear and colorless. The liquid may contain small white particles, but should not contain large or colored particles. Do not use a syringe or dosing pen if it is cracked or broken, if it is expired, or if the liquid is cloudy or contains large or colored particles.

The best place to inject etanercept injection is the front of your middle thighs. You can also inject the medication in your lower stomach below your navel, except the area 2 inches (5 centimeters) around your navel. If someone else is giving you the injection, that person can also inject the medication into your upper arms. If etanercept is injected into the upper arms or stomach, the skin in the area must be stretched to create a firm surface for the injection. Choose a different site for each injection. Do not inject into an area where the skin is tender, bruised, red, hard, or where there are scars or stretch marks. If you have psoriasis, do not inject into skin that is red, thick, raised, or scaly.

Etanercept injection may help control your condition but will not cure it. Continue to use etanercept injection even if you feel well. Do not stop using etanercept without talking to your doctor.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before using etanercept injection,

  • tell your doctor and pharmacist if you are allergic to etanercept or any other medications. If you will be using the prefilled syringe or automatic injection device, tell your doctor if you or the person who will be injecting the medication for you are allergic to rubber or latex.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section, medications for diabetes, and cyclophosphamide (Cytoxan). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have or have ever had seizures; a disease that affects your nervous system, such as multiple sclerosis (MS; loss of coordination, weakness, and numbness due to nerve damage); transverse myelitis (inflammation of the spinal cord that may cause abnormal sensations, loss of sensation, or loss of ability to move the lower body); optic neuritis (inflammation of the nerve that sends messages from the eye to the brain); bleeding problems ; liver disease, or heart failure.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using etanercept, call your doctor. If you use etanercept injection during your pregnancy, be sure to talk to your baby's doctor about this after your baby is born. Your baby may need to receive certain vaccinations later than usual.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are using etanercept.

  • do not have any vaccinations during your treatment with etanercept without talking to your doctor. If your child will be treated with etanercept injection, talk to his or her doctor about vaccinations that should be given before the start of treatment. If possible, your child should be given all vaccinations needed for children of his or her age before beginning treatment.

  • if you are exposed to chickenpox while using etanercept, call your doctor immediately.

Unless your doctor tells you otherwise, continue your normal diet.

Inject the missed dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose and continue your usual dosing schedule. Do not inject a double dose to make up for a missed one.

  • Etanercept may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • redness, itching, pain, or swelling at the site of injection

    • headache

    • nausea

    • vomiting

    • heartburn

    • stomach pain

    • weakness

    • cough

  • Some side effects can be serious. If you experience any of the following side effects or those mentioned in the IMPORTANT WARNING SECTION, call your doctor immediately or get emergency medical help:

    • seizures

    • bruising

    • bleeding

    • pale skin

    • blistering skin

    • rash

    • hives

    • itching

    • swelling of the eyes, face, lips, tongue, throat, arms, hands, feet, ankles, or lower legs

    • difficulty breathing or swallowing

    • rash on the face and arms that worsens in the sun

    • numbness or tingling

    • vision problems

    • weakness in the arms or legs

    • dizziness

    • red, scaly patches or pus-filled bumps on the skin

  • Adults who receive etanercept injection maybe at greater risk of developing lymphoma, leukemia (cancer that begins in the white blood cells), skin cancer, and other types of cancer than adults who do not receive this medication. Talk to your doctor about the risks of receiving etanercept injection.

  • Etanercept injection may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store etanercept injection in the refrigerator but do not freeze. Keep the vials, prefilled syringes, or injection devices in their original cartons to protect them from light. If you have mixed a vial of etanercept powder with the provided liquid, you may store the solution in the refrigerator for up to 14 days.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to etanercept.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are using etanercept.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Penbutolol Penbutolol The metabolism of Acebutolol can be increased when combined with Etanercept.
Triamcinolone Triamcinolone The metabolism of Triamcinolone can be increased when combined with Etanercept.
Zolmitriptan Zolmitriptan The metabolism of Zolmitriptan can be increased when combined with Etanercept.
Zidovudine Injection Zidovudine Injection The metabolism of Zidovudine can be increased when combined with Etanercept.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Etanercept is combined with Linezolid.
Trimipramine Trimipramine The metabolism of Trimipramine can be increased when combined with Etanercept.
Tenofovir Tenofovir The metabolism of Tenofovir can be increased when combined with Etanercept.
Tegaserod Tegaserod The metabolism of Tegaserod can be increased when combined with Etanercept.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be increased when combined with Etanercept.
Infliximab Injection Infliximab Injection Etanercept may increase the immunosuppressive activities of Infliximab.
Voriconazole Voriconazole The metabolism of Voriconazole can be increased when combined with Etanercept.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Peginterferon alfa-2a.
Darifenacin Darifenacin The metabolism of Darifenacin can be increased when combined with Etanercept.
Tipranavir Tipranavir The metabolism of Tipranavir can be increased when combined with Etanercept.
Rasagiline Rasagiline The metabolism of Rasagiline can be increased when combined with Etanercept.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Etanercept.
Rituximab Injection Rituximab Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Rituximab.
Vorinostat Vorinostat The risk or severity of adverse effects can be increased when Etanercept is combined with Vorinostat.
Dronabinol Dronabinol The metabolism of Dronabinol can be increased when combined with Etanercept.
Azacitidine Injection Azacitidine Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Azacitidine.
Budesonide Budesonide The risk or severity of adverse effects can be increased when Etanercept is combined with Budesonide.
Decitabine Injection Decitabine Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Decitabine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Arsenic trioxide.
Tretinoin Tretinoin The metabolism of Tretinoin can be increased when combined with Etanercept.
Bendamustine Injection Bendamustine Injection The metabolism of Bendamustine can be increased when combined with Etanercept.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Etanercept is combined with Alemtuzumab.
Betaxolol Betaxolol The metabolism of Betaxolol can be increased when combined with Etanercept.
Everolimus Everolimus The metabolism of Everolimus can be increased when combined with Etanercept.
Fingolimod Fingolimod Etanercept may increase the immunosuppressive activities of Fingolimod.
Eribulin Injection Eribulin Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Eribulin.
Acetaminophen Injection Acetaminophen Injection The metabolism of Acetaminophen can be increased when combined with Etanercept.
Vilazodone Vilazodone The metabolism of Vilazodone can be increased when combined with Etanercept.
Belimumab Injection Belimumab Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Belimumab.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be increased when combined with Etanercept.
Roflumilast Roflumilast Etanercept may increase the immunosuppressive activities of Roflumilast.
Linagliptin Linagliptin The metabolism of Linagliptin can be increased when combined with Etanercept.
Rivaroxaban Rivaroxaban The metabolism of Rivaroxaban can be increased when combined with Etanercept.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be increased when combined with Etanercept.
Ruxolitinib Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Etanercept.
Vandetanib Vandetanib The metabolism of Vandetanib can be increased when combined with Etanercept.
Vemurafenib Vemurafenib The metabolism of Vemurafenib can be increased when combined with Etanercept.
Vismodegib Vismodegib The metabolism of Vismodegib can be increased when combined with Etanercept.
Belatacept Injection Belatacept Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Belatacept.
Ivacaftor Ivacaftor The metabolism of Ivacaftor can be increased when combined with Etanercept.
Basiliximab Injection Basiliximab Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Basiliximab.
Axitinib Axitinib The metabolism of Axitinib can be increased when combined with Etanercept.
Crizotinib Crizotinib The metabolism of Crizotinib can be increased when combined with Etanercept.
Carfilzomib Injection Carfilzomib Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Carfilzomib.
Enzalutamide Enzalutamide The metabolism of Enzalutamide can be increased when combined with Etanercept.
Mirabegron Mirabegron The metabolism of Mirabegron can be increased when combined with Etanercept.
Regorafenib Regorafenib The metabolism of Regorafenib can be increased when combined with Etanercept.
Bosutinib Bosutinib The metabolism of Bosutinib can be increased when combined with Etanercept.
Teriflunomide Teriflunomide The risk or severity of adverse effects can be increased when Etanercept is combined with Teriflunomide.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be increased when combined with Etanercept.
Tofacitinib Tofacitinib The risk or severity of adverse effects can be increased when Etanercept is combined with Tofacitinib.
Alogliptin Alogliptin The metabolism of Alogliptin can be increased when combined with Etanercept.
Dimethyl Fumarate Dimethyl Fumarate The risk or severity of adverse effects can be increased when Etanercept is combined with Dimethyl fumarate.
Ponatinib Ponatinib The metabolism of Ponatinib can be increased when combined with Etanercept.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be increased when combined with Etanercept.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be increased when combined with Etanercept.
Apixaban Apixaban The metabolism of Apixaban can be increased when combined with Etanercept.
Dabrafenib Dabrafenib The metabolism of Dabrafenib can be increased when combined with Etanercept.
Ospemifene Ospemifene The metabolism of Ospemifene can be increased when combined with Etanercept.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Etanercept.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be increased when combined with Etanercept.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Etanercept.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be increased when combined with Etanercept.
Lomitapide Lomitapide The metabolism of Lomitapide can be increased when combined with Etanercept.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be increased when combined with Etanercept.
Apremilast Apremilast The therapeutic efficacy of Apremilast can be decreased when used in combination with Etanercept.
Ceritinib Ceritinib The metabolism of Ceritinib can be increased when combined with Etanercept.
Siltuximab Injection Siltuximab Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Siltuximab.
Vedolizumab Injection Vedolizumab Injection The risk or severity of infection can be increased when Etanercept is combined with Vedolizumab.
Belinostat Injection Belinostat Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Belinostat.
Idelalisib Idelalisib The metabolism of Idelalisib can be increased when combined with Etanercept.
Testosterone Injection Testosterone Injection The metabolism of Testosterone can be increased when combined with Etanercept.
Vorapaxar Vorapaxar The metabolism of Vorapaxar can be increased when combined with Etanercept.
Suvorexant Suvorexant The metabolism of Suvorexant can be increased when combined with Etanercept.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Peginterferon beta-1a.
Olaparib Olaparib The metabolism of Olaparib can be increased when combined with Etanercept.
Blinatumomab Injection Blinatumomab Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Blinatumomab.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be increased when combined with Etanercept.
Riociguat Riociguat The metabolism of Riociguat can be increased when combined with Etanercept.
Pirfenidone Pirfenidone The metabolism of Pirfenidone can be increased when combined with Etanercept.
Nintedanib Nintedanib The metabolism of Nintedanib can be increased when combined with Etanercept.
Secukinumab Injection Secukinumab Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Secukinumab.
Palbociclib Palbociclib The metabolism of Palbociclib can be increased when combined with Etanercept.
Panobinostat Panobinostat The metabolism of Panobinostat can be increased when combined with Etanercept.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Dinutuximab.
Sonidegib Sonidegib The metabolism of Sonidegib can be increased when combined with Etanercept.
Daclatasvir Daclatasvir The metabolism of Daclatasvir can be increased when combined with Etanercept.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be increased when combined with Etanercept.
Ziprasidone Injection Ziprasidone Injection The metabolism of Ziprasidone can be increased when combined with Etanercept.
Cariprazine Cariprazine The metabolism of Cariprazine can be increased when combined with Etanercept.
Cobimetinib Cobimetinib The metabolism of Cobimetinib can be increased when combined with Etanercept.
Mepolizumab Injection Mepolizumab Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Mepolizumab.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Etanercept.
Osimertinib Osimertinib The metabolism of Osimertinib can be increased when combined with Etanercept.
Alectinib Alectinib The metabolism of Alectinib can be increased when combined with Etanercept.
Ixazomib Ixazomib The metabolism of Ixazomib can be increased when combined with Etanercept.
Lesinurad Lesinurad The metabolism of Lesinurad can be increased when combined with Etanercept.
Ixekizumab Injection Ixekizumab Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Ixekizumab.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be increased when combined with Etanercept.
Venetoclax Venetoclax The metabolism of Venetoclax can be increased when combined with Etanercept.
Cobicistat Cobicistat The metabolism of Cobicistat can be increased when combined with Etanercept.
Selexipag Selexipag The metabolism of Selexipag can be increased when combined with Etanercept.
Rucaparib Rucaparib The metabolism of Rucaparib can be increased when combined with Etanercept.
Ribociclib Ribociclib The metabolism of Ribociclib can be increased when combined with Etanercept.
Brodalumab Injection Brodalumab Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Brodalumab.
Brigatinib Brigatinib The metabolism of Brigatinib can be increased when combined with Etanercept.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be increased when combined with Etanercept.
Valbenazine Valbenazine The metabolism of Valbenazine can be increased when combined with Etanercept.
Ocrelizumab Injection Ocrelizumab Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Ocrelizumab.
Sarilumab Injection Sarilumab Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Sarilumab.
Midostaurin Midostaurin The metabolism of Midostaurin can be increased when combined with Etanercept.
Neratinib Neratinib The metabolism of Neratinib can be increased when combined with Etanercept.
Guselkumab Injection Guselkumab Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Guselkumab.
Enasidenib Enasidenib The metabolism of Enasidenib can be increased when combined with Etanercept.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Etanercept.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Etanercept.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be increased when combined with Etanercept.
Acalabrutinib Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Etanercept.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Gemtuzumab ozogamicin.
Letermovir Letermovir The metabolism of Letermovir can be increased when combined with Etanercept.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be increased when combined with Etanercept.
Buprenorphine Injection Buprenorphine Injection The metabolism of Buprenorphine can be increased when combined with Etanercept.
Apalutamide Apalutamide The metabolism of Apalutamide can be increased when combined with Etanercept.
Baricitinib Baricitinib The metabolism of Baricitinib can be increased when combined with Etanercept.
Eliglustat Eliglustat The metabolism of Eliglustat can be increased when combined with Etanercept.
Encorafenib Encorafenib The metabolism of Encorafenib can be increased when combined with Etanercept.
Binimetinib Binimetinib The metabolism of Binimetinib can be increased when combined with Etanercept.
Ivosidenib Ivosidenib The metabolism of Ivosidenib can be increased when combined with Etanercept.
Elagolix Elagolix The metabolism of Elagolix can be increased when combined with Etanercept.
Doravirine Doravirine The metabolism of Doravirine can be increased when combined with Etanercept.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be increased when combined with Etanercept.
Cannabidiol Cannabidiol The metabolism of Cannabidiol can be increased when combined with Etanercept.
Dacomitinib Dacomitinib The metabolism of Dacomitinib can be increased when combined with Etanercept.
Duvelisib Duvelisib The metabolism of Duvelisib can be increased when combined with Etanercept.
Stiripentol Stiripentol The metabolism of Stiripentol can be increased when combined with Etanercept.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be increased when combined with Etanercept.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be increased when combined with Etanercept.
Theophylline Theophylline The metabolism of Theophylline can be increased when combined with Etanercept.
Trazodone Trazodone The metabolism of Trazodone can be increased when combined with Etanercept.
Thioguanine Thioguanine The risk or severity of adverse effects can be increased when Etanercept is combined with Tioguanine.
Thioridazine Thioridazine The metabolism of Thioridazine can be increased when combined with Etanercept.
Trifluoperazine Trifluoperazine The metabolism of Trifluoperazine can be increased when combined with Etanercept.
Bleomycin Bleomycin The risk or severity of adverse effects can be increased when Etanercept is combined with Bleomycin.
Sulfadiazine Sulfadiazine The metabolism of Sulfadiazine can be increased when combined with Etanercept.
Benztropine Benztropine The metabolism of Benzatropine can be increased when combined with Etanercept.
Azathioprine Azathioprine The metabolism of Azathioprine can be increased when combined with Etanercept.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be increased when combined with Etanercept.
Warfarin Warfarin The metabolism of Warfarin can be increased when combined with Etanercept.
Triamterene Triamterene The metabolism of Triamterene can be increased when combined with Etanercept.
Valproic Acid Valproic Acid The metabolism of Valproic acid can be increased when combined with Etanercept.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be increased when combined with Etanercept.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be increased when combined with Etanercept.
Tolazamide Tolazamide The metabolism of Tolazamide can be increased when combined with Etanercept.
Brompheniramine Brompheniramine The metabolism of Brompheniramine can be increased when combined with Etanercept.
Carisoprodol Carisoprodol The metabolism of Carisoprodol can be increased when combined with Etanercept.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Etanercept is combined with Mercaptopurine.
Thiotepa Injection Thiotepa Injection The metabolism of Thiotepa can be increased when combined with Etanercept.
Vincristine Injection Vincristine Injection The metabolism of Vincristine can be increased when combined with Etanercept.
Vinblastine Vinblastine The metabolism of Vinblastine can be increased when combined with Etanercept.
Thiothixene Thiothixene The metabolism of Thiothixene can be increased when combined with Etanercept.
Aspirin Aspirin The metabolism of Acetylsalicylic acid can be increased when combined with Etanercept.
Triazolam Triazolam The metabolism of Triazolam can be increased when combined with Etanercept.
Trimethoprim Trimethoprim The metabolism of Trimethoprim can be increased when combined with Etanercept.
Timolol Timolol The metabolism of Timolol can be increased when combined with Etanercept.
Verapamil Verapamil The metabolism of Verapamil can be increased when combined with Etanercept.
Atenolol Atenolol The metabolism of Atenolol can be increased when combined with Etanercept.
Streptozocin Streptozocin The risk or severity of adverse effects can be increased when Etanercept is combined with Streptozocin.
Buspirone Buspirone The metabolism of Buspirone can be increased when combined with Etanercept.
Teniposide Injection Teniposide Injection The metabolism of Teniposide can be increased when combined with Etanercept.
Tramadol Tramadol The metabolism of Tramadol can be increased when combined with Etanercept.
Lansoprazole Lansoprazole The metabolism of Lansoprazole can be increased when combined with Etanercept.
Ticlopidine Ticlopidine The metabolism of Ticlopidine can be increased when combined with Etanercept.
Gemcitabine Injection Gemcitabine Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Gemcitabine.
Indinavir Indinavir The metabolism of Indinavir can be increased when combined with Etanercept.
Zafirlukast Zafirlukast The metabolism of Zafirlukast can be increased when combined with Etanercept.
Mirtazapine Mirtazapine The metabolism of Mirtazapine can be increased when combined with Etanercept.
Donepezil Donepezil The metabolism of Donepezil can be increased when combined with Etanercept.
Azithromycin Azithromycin The metabolism of Azithromycin can be increased when combined with Etanercept.
Carvedilol Carvedilol The metabolism of Carvedilol can be increased when combined with Etanercept.
Capecitabine Capecitabine The metabolism of Capecitabine can be increased when combined with Etanercept.
Efavirenz Efavirenz The metabolism of Efavirenz can be increased when combined with Etanercept.
Sildenafil Sildenafil The metabolism of Sildenafil can be increased when combined with Etanercept.
Celecoxib Celecoxib The metabolism of Celecoxib can be increased when combined with Etanercept.
Tolterodine Tolterodine The metabolism of Tolterodine can be increased when combined with Etanercept.
Thalidomide Thalidomide The metabolism of Thalidomide can be increased when combined with Etanercept.
Rabeprazole Rabeprazole The metabolism of Rabeprazole can be increased when combined with Etanercept.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists