Fedratinib

Generic name: Pronounced as (fed ra' ti nib)
Brand names
  • Inrebic®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 02/15/2022

Fedratinib may cause encephalopathy (a serious and potentially fatal disorder of the nervous system), including Wernicke's encephalopathy (a type of encephalopathy caused by a lack of thiamine [vitamin B1]). Tell your doctor if you have or have ever had a thiamine deficiency. If you experience any of the following symptoms, stop taking fedratinib and call your doctor immediately or get emergency medical treatment: difficulty moving or keeping your balance, weakness of the legs or arms that keeps getting worse, confusion, drowsiness, difficulty understanding or speaking, loss of memory, vision problems (including double vision and abnormal eye movements), or changes in personality.

Your doctor may prescribe medications to reduce the risk of side effects you may have from taking fedratinib. Tell your doctor right away if you have nausea, vomiting, diarrhea, or weight loss that does not get better with treatment.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to fedratinib.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with fedratinib and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.

Fedratinib is used to treat adults with certain types of myelofibrosis (MF; a cancer of the bone marrow in which the bone marrow is replaced by scar tissue and causes decreased blood cell production). Fedratinib is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop or slow the spread of cancer cells.

Fedratinib comes as a capsule to take by mouth. It is usually taken once a day, with or without food. Taking fedratinib with a high fat meal may help to reduce nausea and vomiting. Take fedratinib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take fedratinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will order blood tests before and during your treatment to see how you are affected by this medication. Your doctor may increase or decrease your dose of fedratinib during your treatment, or may tell you to stop taking fedratinib temporarily or permanently. This depends on how well the medication works for you, your lab test results, and if you experience side effects. Talk to your doctor about how you are feeling during your treatment.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking fedratinib,

  • tell your doctor and pharmacist if you are allergic to fedratinib, any other medications, or any of the ingredients in fedratinib capsules. Ask your pharmacist or check the Medication Guide for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: clarithromycin (Biaxin, in PrevPac), diltiazem (Cardizem, Dilacor, Tiazac, others), erythromycin (E.E.S., E-mycin, Erythrocin), idelalisib (Zydelig), indinavir (Crixivan), itraconazole (Sporanox), ketoconazole (Nizoral), metoprolol (Lopressor, Toprol XL, in Dutoprol, others), midazolam (Versed), nefazodone, nelfinavir (Viracept), omeprazole (Prilosec, in Zegerid), pantoprazole (Protonix), ribociclib (Kisqali, Kisqali, in Femera), ritonavir (Norvir), ruxolitinib (Jakafi), and saquinavir (Invirase). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with fedratinib, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you if you smoke or if you have ever smoked. Also tell your doctor if you have or have ever had cancer, pancreatitis (swelling of the pancreas), blood clots, a stroke, a heart attack or other heart problems, liver or kidney disease.

  • tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking fedratinib, call your doctor.

  • do not breastfeed during your treatment with fedratinib and for at least 1 month after your final dose.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking fedratinib.

Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medication.

Skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Fedratinib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • nausea

    • vomiting

    • diarrhea

    • constipation

    • tiredness

    • muscle spasms

    • arm, leg, or bone pain

    • headache

    • weight gain

    • dizziness

  • Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical treatment:

    • unusual bleeding or bruising

    • fever, chills, cough, painful or frequent urination, or other signs of infection

    • nausea, extreme tiredness, unusual bruising or bleeding, lack of energy, loss of appetite, pain in the upper right part of the stomach, yellowing of the skin or eyes, or flu-like symptoms

    • shortness of breath, fast heartbeat, headache, dizziness, pale skin, confusion, or tiredness

    • pain in the chest, arms, back, neck, jaw, or stomach; breaking out in cold sweat; lightheadedness

    • slow or difficult speech; sudden weakness or numbness of the face, arm or leg; sudden headache; sudden vision problems; sudden difficulty walking

    • swelling, pain, tenderness, warmth or redness in one or both legs

    • shortness of breath, coughing up blood, fast heartbeat, fast breathing, pain when breathing deeply

  • Fedratinib may increase your risk of developing other cancers, such as lymphoma (cancer that begins in the cells that fight infection). Talk to your doctor about the risks of receiving this medication.

  • Fedratinib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Repaglinide Repaglinide The excretion of Repaglinide can be decreased when combined with Fedratinib.
Leflunomide Leflunomide Fedratinib may decrease the excretion rate of Leflunomide which could result in a higher serum level.
Delavirdine Delavirdine The metabolism of Fedratinib can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Nevirapine can be decreased when combined with Fedratinib.
Atorvastatin Atorvastatin The excretion of Atorvastatin can be decreased when combined with Fedratinib.
Dolasetron Dolasetron The metabolism of Dolasetron can be decreased when combined with Fedratinib.
Cilostazol Cilostazol The metabolism of Cilostazol can be decreased when combined with Fedratinib.
Clopidogrel Clopidogrel The metabolism of Fedratinib can be decreased when combined with Clopidogrel.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The serum concentration of Fedratinib can be increased when it is combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Fedratinib may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate Fenofibrate The metabolism of Fedratinib can be decreased when combined with Fenofibrate.
Paregoric Paregoric The serum concentration of Morphine can be increased when it is combined with Fedratinib.
Penbutolol Penbutolol The metabolism of Acebutolol can be decreased when combined with Fedratinib.
Reserpine Reserpine The serum concentration of Fedratinib can be increased when it is combined with Reserpine.
Sumatriptan Sumatriptan Fedratinib may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus The serum concentration of Fedratinib can be increased when it is combined with Tacrolimus.
Fluconazole Injection Fluconazole Injection The serum concentration of Fedratinib can be increased when it is combined with Fluconazole.
Levofloxacin Injection Levofloxacin Injection The excretion of Levofloxacin can be decreased when combined with Fedratinib.
Meperidine Injection Meperidine Injection The metabolism of Meperidine can be decreased when combined with Fedratinib.
Metoclopramide Injection Metoclopramide Injection The metabolism of Metoclopramide can be decreased when combined with Fedratinib.
Morphine Injection Morphine Injection The serum concentration of Morphine can be increased when it is combined with Fedratinib.
Zidovudine Injection Zidovudine Injection Fedratinib may decrease the excretion rate of Zidovudine which could result in a higher serum level.
Altretamine Altretamine The metabolism of Amphetamine can be decreased when combined with Fedratinib.
Cyclosporine Cyclosporine The serum concentration of Fedratinib can be increased when it is combined with Cyclosporine.
Ondansetron Ondansetron The metabolism of Ondansetron can be decreased when combined with Fedratinib.
Torsemide Torsemide The excretion of Torasemide can be decreased when combined with Fedratinib.
Olanzapine Olanzapine The metabolism of Fedratinib can be decreased when combined with Olanzapine.
Hydroxychloroquine Hydroxychloroquine The metabolism of Hydroxychloroquine can be decreased when combined with Fedratinib.
Oxcarbazepine Oxcarbazepine The metabolism of Fedratinib can be decreased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole The metabolism of Fedratinib can be decreased when combined with Pantoprazole.
Telmisartan Telmisartan The metabolism of Fedratinib can be decreased when combined with Telmisartan.
Anakinra Anakinra The metabolism of Fedratinib can be increased when combined with Anakinra.
Trimipramine Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Fedratinib.
Etanercept Injection Etanercept Injection The metabolism of Fedratinib can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Fedratinib can be decreased when combined with Modafinil.
Tenofovir Tenofovir The serum concentration of Tenofovir can be increased when it is combined with Fedratinib.
Sirolimus Sirolimus The serum concentration of Fedratinib can be increased when it is combined with Sirolimus.
Escitalopram Escitalopram The metabolism of Fedratinib can be decreased when combined with Escitalopram.
Zonisamide Zonisamide The serum concentration of Fedratinib can be increased when it is combined with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Fedratinib can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Fedratinib.
Atomoxetine Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Fedratinib.
Ezetimibe Ezetimibe Fedratinib may decrease the excretion rate of Ezetimibe which could result in a higher serum level.
Teriparatide Injection Teriparatide Injection The therapeutic efficacy of Teriparatide can be decreased when used in combination with Fedratinib.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Fedratinib.
Eletriptan Eletriptan The metabolism of Eletriptan can be decreased when combined with Fedratinib.
Rosuvastatin Rosuvastatin Fedratinib may decrease the excretion rate of Rosuvastatin which could result in a higher serum level.
Vardenafil Vardenafil The serum concentration of Fedratinib can be increased when it is combined with Vardenafil.
Aprepitant Aprepitant The metabolism of Fedratinib can be decreased when combined with Aprepitant.
Emtricitabine Emtricitabine The excretion of Emtricitabine can be decreased when combined with Fedratinib.
Memantine Memantine The metabolism of Fedratinib can be decreased when combined with Memantine.
Tegaserod Tegaserod Fedratinib may decrease the excretion rate of Tegaserod which could result in a higher serum level.
Progesterone Progesterone The metabolism of Fedratinib can be decreased when combined with Progesterone.
Darbepoetin Alfa Injection Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Fedratinib.
Infliximab Injection Infliximab Injection The metabolism of Fedratinib can be increased when combined with Infliximab.
Protriptyline Protriptyline The metabolism of Protriptyline can be decreased when combined with Fedratinib.
Rifaximin Rifaximin The serum concentration of Rifaximin can be increased when it is combined with Fedratinib.
Duloxetine Duloxetine The metabolism of Duloxetine can be decreased when combined with Fedratinib.
Bosentan Bosentan The excretion of Bosentan can be decreased when combined with Fedratinib.
Erlotinib Erlotinib The metabolism of Erlotinib can be decreased when combined with Fedratinib.
Ganciclovir Ganciclovir The excretion of Ganciclovir can be decreased when combined with Fedratinib.
Solifenacin Solifenacin The metabolism of Solifenacin can be decreased when combined with Fedratinib.
Voriconazole Voriconazole The metabolism of Fedratinib can be decreased when combined with Voriconazole.
Dextroamphetamine Dextroamphetamine The metabolism of Amphetamine can be decreased when combined with Fedratinib.
Ramelteon Ramelteon The metabolism of Fedratinib can be decreased when combined with Ramelteon.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Fedratinib.
Tipranavir Tipranavir The metabolism of Fedratinib can be decreased when combined with Tipranavir.
Felbamate Felbamate The metabolism of Fedratinib can be decreased when combined with Felbamate.
Ranolazine Ranolazine The serum concentration of Ranolazine can be increased when it is combined with Fedratinib.
Abatacept Injection Abatacept Injection The metabolism of Fedratinib can be increased when combined with Abatacept.
Imatinib Imatinib Fedratinib may decrease the excretion rate of Imatinib which could result in a higher serum level.
Sitagliptin Sitagliptin The serum concentration of Sitagliptin can be increased when it is combined with Fedratinib.
Gefitinib Gefitinib Fedratinib may decrease the excretion rate of Gefitinib which could result in a higher serum level.
Paliperidone Paliperidone The serum concentration of Fedratinib can be increased when it is combined with Paliperidone.
Bortezomib Bortezomib The serum concentration of Fedratinib can be increased when it is combined with Bortezomib.
Clofarabine Injection Clofarabine Injection Fedratinib may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Oxaliplatin Injection Oxaliplatin Injection Fedratinib may decrease the excretion rate of Oxaliplatin which could result in a higher serum level.
Posaconazole Posaconazole The serum concentration of Fedratinib can be increased when it is combined with Posaconazole.
Lisdexamfetamine Lisdexamfetamine The metabolism of Lisdexamfetamine can be decreased when combined with Fedratinib.
Sorafenib Sorafenib Fedratinib may decrease the excretion rate of Sorafenib which could result in a higher serum level.
Lapatinib Lapatinib The serum concentration of Fedratinib can be increased when it is combined with Lapatinib.
Dasatinib Dasatinib The serum concentration of Dasatinib can be increased when it is combined with Fedratinib.
Mexiletine Mexiletine The metabolism of Mexiletine can be decreased when combined with Fedratinib.
Armodafinil Armodafinil The metabolism of Fedratinib can be decreased when combined with Armodafinil.
Ivermectin Ivermectin Fedratinib may decrease the excretion rate of Ivermectin which could result in a higher serum level.
Temsirolimus Temsirolimus The serum concentration of Fedratinib can be increased when it is combined with Temsirolimus.
Nilotinib Nilotinib The serum concentration of Fedratinib can be increased when it is combined with Nilotinib.
Toremifene Toremifene The serum concentration of Fedratinib can be increased when it is combined with Toremifene.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Fedratinib can be decreased when combined with Chloramphenicol.
Etravirine Etravirine The metabolism of Fedratinib can be decreased when combined with Etravirine.
Mitoxantrone Injection Mitoxantrone Injection Fedratinib may decrease the excretion rate of Mitoxantrone which could result in a higher serum level.
Cevimeline Cevimeline The metabolism of Cevimeline can be decreased when combined with Fedratinib.
Nebivolol Nebivolol The metabolism of Fedratinib can be decreased when combined with Nebivolol.
Bendamustine Injection Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Fedratinib.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Fedratinib.
Certolizumab Injection Certolizumab Injection The metabolism of Fedratinib can be increased when combined with Certolizumab pegol.
Irinotecan Injection Irinotecan Injection Fedratinib may decrease the excretion rate of Irinotecan which could result in a higher serum level.
Praziquantel Praziquantel The metabolism of Fedratinib can be decreased when combined with Praziquantel.
Silodosin Silodosin The serum concentration of Silodosin can be increased when it is combined with Fedratinib.
Dexlansoprazole Dexlansoprazole The metabolism of Fedratinib can be decreased when combined with Dexlansoprazole.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Fedratinib.
Betaxolol Betaxolol The metabolism of Betaxolol can be decreased when combined with Fedratinib.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Fedratinib.
Lacosamide Lacosamide The metabolism of Fedratinib can be decreased when combined with Lacosamide.
Everolimus Everolimus The serum concentration of Everolimus can be increased when it is combined with Fedratinib.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The serum concentration of Fedratinib can be increased when it is combined with Tolvaptan.
Dronedarone Dronedarone The serum concentration of Fedratinib can be increased when it is combined with Dronedarone.
Pralatrexate Injection Pralatrexate Injection Fedratinib may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Fedratinib.
Romidepsin Injection Romidepsin Injection The serum concentration of Romidepsin can be increased when it is combined with Fedratinib.
Tapentadol Tapentadol The metabolism of Tapentadol can be decreased when combined with Fedratinib.
Topotecan Topotecan The serum concentration of Topotecan can be increased when it is combined with Fedratinib.
Golimumab Injection Golimumab Injection The metabolism of Fedratinib can be increased when combined with Golimumab.
Pazopanib Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Fedratinib.
Pitavastatin Pitavastatin Fedratinib may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Albendazole Albendazole The metabolism of Fedratinib can be decreased when combined with Albendazole.
Oxymorphone Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Fedratinib.
Tocilizumab Injection Tocilizumab Injection The metabolism of Fedratinib can be increased when combined with Tocilizumab.
Cabazitaxel Injection Cabazitaxel Injection The serum concentration of Fedratinib can be increased when it is combined with Cabazitaxel.
Acetaminophen Injection Acetaminophen Injection The serum concentration of Acetaminophen can be increased when it is combined with Fedratinib.
Vilazodone Vilazodone The metabolism of Fedratinib can be decreased when combined with Vilazodone.
Linagliptin Linagliptin The serum concentration of Fedratinib can be increased when it is combined with Linagliptin.
Telaprevir Telaprevir Fedratinib may decrease the excretion rate of Glecaprevir which could result in a higher serum level.
Potassium Iodide Potassium Iodide The therapeutic efficacy of Potassium Iodide can be decreased when used in combination with Fedratinib.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Fedratinib can be decreased when combined with Cyclophosphamide.
Abiraterone Abiraterone The metabolism of Fedratinib can be decreased when combined with Abiraterone.
Rivaroxaban Rivaroxaban The serum concentration of Rivaroxaban can be increased when it is combined with Fedratinib.
Ticagrelor Ticagrelor The serum concentration of Fedratinib can be increased when it is combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Fedratinib.
Vandetanib Vandetanib The serum concentration of Fedratinib can be increased when it is combined with Vandetanib.
Clobazam Clobazam The serum concentration of Clobazam can be increased when it is combined with Fedratinib.
Vemurafenib Vemurafenib The serum concentration of Fedratinib can be increased when it is combined with Vemurafenib.
Vismodegib Vismodegib The metabolism of Fedratinib can be decreased when combined with Vismodegib.
Ivacaftor Ivacaftor The serum concentration of Fedratinib can be increased when it is combined with Ivacaftor.
Axitinib Axitinib The serum concentration of Axitinib can be increased when it is combined with Fedratinib.
Crizotinib Crizotinib The serum concentration of Fedratinib can be increased when it is combined with Crizotinib.
Cabergoline Cabergoline The serum concentration of Cabergoline can be increased when it is combined with Fedratinib.
Ambrisentan Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Fedratinib.
Carfilzomib Injection Carfilzomib Injection The serum concentration of Carfilzomib can be increased when it is combined with Fedratinib.
Enzalutamide Enzalutamide The serum concentration of Fedratinib can be increased when it is combined with Enzalutamide.
Mirabegron Mirabegron The serum concentration of Fedratinib can be increased when it is combined with Mirabegron.
Regorafenib Regorafenib The serum concentration of Fedratinib can be increased when it is combined with Regorafenib.
Bosutinib Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Fedratinib.
Teriflunomide Teriflunomide Fedratinib may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Alogliptin Alogliptin The metabolism of Alogliptin can be decreased when combined with Fedratinib.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Fedratinib.
Pomalidomide Pomalidomide The serum concentration of Pomalidomide can be increased when it is combined with Fedratinib.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The serum concentration of Trastuzumab emtansine can be increased when it is combined with Fedratinib.
Apixaban Apixaban Fedratinib may decrease the excretion rate of Apixaban which could result in a higher serum level.
Canagliflozin Canagliflozin The serum concentration of Fedratinib can be increased when it is combined with Canagliflozin.
Dabrafenib Dabrafenib The serum concentration of Fedratinib can be decreased when it is combined with Dabrafenib.
Dolutegravir Dolutegravir Fedratinib may decrease the excretion rate of Dolutegravir which could result in a higher serum level.
Afatinib Afatinib The serum concentration of Afatinib can be increased when it is combined with Fedratinib.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Fedratinib.
Vortioxetine Vortioxetine The metabolism of Fedratinib can be decreased when combined with Vortioxetine.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Fedratinib.
Lomitapide Lomitapide The serum concentration of Fedratinib can be increased when it is combined with Lomitapide.
Simeprevir Simeprevir The serum concentration of Fedratinib can be increased when it is combined with Simeprevir.
Sofosbuvir Sofosbuvir Fedratinib may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Fedratinib.
Apremilast Apremilast The metabolism of Fedratinib can be increased when combined with Apremilast.
Ceritinib Ceritinib The serum concentration of Ceritinib can be increased when it is combined with Fedratinib.
Siltuximab Injection Siltuximab Injection The metabolism of Fedratinib can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The metabolism of Fedratinib can be decreased when combined with Eslicarbazepine.
Belinostat Injection Belinostat Injection The serum concentration of Belinostat can be increased when it is combined with Fedratinib.
Idelalisib Idelalisib The serum concentration of Fedratinib can be increased when it is combined with Idelalisib.
Testosterone Injection Testosterone Injection Fedratinib may decrease the excretion rate of Testosterone which could result in a higher serum level.
Oritavancin Injection Oritavancin Injection The metabolism of Fedratinib can be decreased when combined with Oritavancin.
Vorapaxar Vorapaxar The serum concentration of Fedratinib can be increased when it is combined with Vorapaxar.
Hydrocodone Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Fedratinib.
Suvorexant Suvorexant The serum concentration of Fedratinib can be increased when it is combined with Suvorexant.
Edoxaban Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Fedratinib.
Caspofungin Injection Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Fedratinib.
Methamphetamine Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Fedratinib.
Riociguat Riociguat Fedratinib may decrease the excretion rate of Riociguat which could result in a higher serum level.
Nintedanib Nintedanib The serum concentration of Nintedanib can be increased when it is combined with Fedratinib.
Secukinumab Injection Secukinumab Injection The metabolism of Fedratinib can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Risperidone can be decreased when combined with Fedratinib.
Palbociclib Palbociclib Fedratinib may decrease the excretion rate of Palbociclib which could result in a higher serum level.
Lenvatinib Lenvatinib Fedratinib may decrease the excretion rate of Lenvatinib which could result in a higher serum level.
Naloxegol Naloxegol The serum concentration of Naloxegol can be increased when it is combined with Fedratinib.
Panobinostat Panobinostat The serum concentration of Panobinostat can be increased when it is combined with Fedratinib.
Haloperidol Injection Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Fedratinib.
Isavuconazonium Injection Isavuconazonium Injection The serum concentration of Fedratinib can be increased when it is combined with Isavuconazonium.
Flibanserin Flibanserin The serum concentration of Fedratinib can be increased when it is combined with Flibanserin.
Rolapitant Rolapitant The serum concentration of Fedratinib can be increased when it is combined with Rolapitant.
Daclatasvir Daclatasvir The serum concentration of Fedratinib can be increased when it is combined with Daclatasvir.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Fedratinib.
Cariprazine Cariprazine The metabolism of Cariprazine can be decreased when combined with Fedratinib.
Eluxadoline Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Fedratinib.
Cobimetinib Cobimetinib The serum concentration of Cobimetinib can be increased when it is combined with Fedratinib.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Fedratinib.
Osimertinib Osimertinib The serum concentration of Osimertinib can be increased when it is combined with Fedratinib.
Rifapentine Rifapentine The metabolism of Fedratinib can be increased when combined with Rifapentine.
Venetoclax Venetoclax The serum concentration of Fedratinib can be increased when it is combined with Venetoclax.
Cobicistat Cobicistat The serum concentration of Fedratinib can be increased when it is combined with Cobicistat.
Selexipag Selexipag The serum concentration of Selexipag can be increased when it is combined with Fedratinib.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Fedratinib.
Rucaparib Rucaparib Fedratinib may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Parathyroid Hormone Injection Parathyroid Hormone Injection The therapeutic efficacy of Parathyroid hormone can be decreased when used in combination with Fedratinib.
Brigatinib Brigatinib Fedratinib may decrease the excretion rate of Brigatinib which could result in a higher serum level.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Fedratinib can be decreased when combined with Doxepin.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Fedratinib.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Fedratinib.
Safinamide Safinamide The metabolism of Fedratinib can be decreased when combined with Safinamide.
Midostaurin Midostaurin The metabolism of Fedratinib can be decreased when combined with Midostaurin.
Neratinib Neratinib The serum concentration of Fedratinib can be increased when it is combined with Neratinib.
Abaloparatide Injection Abaloparatide Injection The therapeutic efficacy of Abaloparatide can be decreased when used in combination with Fedratinib.
Enasidenib Enasidenib The metabolism of Enasidenib can be decreased when combined with Fedratinib.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Inotuzumab ozogamicin can be increased when it is combined with Fedratinib.
Copanlisib Injection Copanlisib Injection The serum concentration of Copanlisib can be increased when it is combined with Fedratinib.
Delafloxacin Delafloxacin Fedratinib may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib Abemaciclib The serum concentration of Abemaciclib can be increased when it is combined with Fedratinib.
Betrixaban Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Fedratinib.
Letermovir Letermovir The metabolism of Letermovir can be increased when combined with Fedratinib.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Fedratinib.
Ertugliflozin Ertugliflozin Fedratinib may decrease the excretion rate of Ertugliflozin which could result in a higher serum level.
Buprenorphine Injection Buprenorphine Injection The metabolism of Fedratinib can be decreased when combined with Buprenorphine.
Apalutamide Apalutamide The serum concentration of Fedratinib can be increased when it is combined with Apalutamide.
Penicillamine Penicillamine The excretion of Penicillamine can be decreased when combined with Fedratinib.
Avatrombopag Avatrombopag The serum concentration of Avatrombopag can be increased when it is combined with Fedratinib.
Baricitinib Baricitinib The excretion of Baricitinib can be decreased when combined with Fedratinib.
Lofexidine Lofexidine The metabolism of Lofexidine can be decreased when combined with Fedratinib.
Eliglustat Eliglustat The serum concentration of Fedratinib can be increased when it is combined with Eliglustat.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Fedratinib.
Binimetinib Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Fedratinib.
Ivosidenib Ivosidenib The serum concentration of Ivosidenib can be increased when it is combined with Fedratinib.
Lusutrombopag Lusutrombopag Fedratinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level.
Elagolix Elagolix The serum concentration of Elagolix can be increased when it is combined with Fedratinib.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Fedratinib.
Dacomitinib Dacomitinib The serum concentration of Dacomitinib can be increased when it is combined with Fedratinib.
Duvelisib Duvelisib Fedratinib may decrease the excretion rate of Duvelisib which could result in a higher serum level.
Omadacycline Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Fedratinib.
Sarecycline Sarecycline The serum concentration of Fedratinib can be increased when it is combined with Sarecycline.
Stiripentol Stiripentol The metabolism of Fedratinib can be decreased when combined with Stiripentol.
Talazoparib Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Fedratinib.
Gilteritinib Gilteritinib The serum concentration of Gilteritinib can be increased when it is combined with Fedratinib.
Glasdegib Glasdegib Fedratinib may decrease the excretion rate of Glasdegib which could result in a higher serum level.
Lorlatinib Lorlatinib The metabolism of Fedratinib can be decreased when combined with Lorlatinib.
Larotrectinib Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Fedratinib.
Methoxy Polyethylene Glycol-Epoetin Beta Injection Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Fedratinib.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The excretion of Paclitaxel can be decreased when combined with Fedratinib.
Rifamycin Rifamycin The metabolism of Fedratinib can be increased when combined with Rifamycin.
Prucalopride Prucalopride The serum concentration of Prucalopride can be increased when it is combined with Fedratinib.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Fedratinib can be increased when combined with Emapalumab.
Acyclovir Ophthalmic Acyclovir Ophthalmic The excretion of Acyclovir can be decreased when combined with Fedratinib.
Erdafitinib Erdafitinib The serum concentration of Fedratinib can be increased when it is combined with Erdafitinib.
Esomeprazole Injection Esomeprazole Injection The metabolism of Fedratinib can be decreased when combined with Esomeprazole.
Alpelisib Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Fedratinib.
Cladribine Cladribine Fedratinib may decrease the excretion rate of Cladribine which could result in a higher serum level.
Solriamfetol Solriamfetol The excretion of Solriamfetol can be decreased when combined with Fedratinib.
Darolutamide Darolutamide Fedratinib may decrease the excretion rate of Darolutamide which could result in a higher serum level.
Triclabendazole Triclabendazole The metabolism of Fedratinib can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The serum concentration of Fedratinib can be increased when it is combined with Entrectinib.
Istradefylline Istradefylline The serum concentration of Fedratinib can be increased when it is combined with Istradefylline.
Pitolisant Pitolisant The serum concentration of Fedratinib can be decreased when it is combined with Pitolisant.
Lefamulin Lefamulin Fedratinib may decrease the excretion rate of Lefamulin which could result in a higher serum level.
Phenytoin Injection Phenytoin Injection The metabolism of Fedratinib can be increased when combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fedratinib can be decreased when combined with Fosphenytoin.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Fedratinib.
Voxelotor Voxelotor The metabolism of Voxelotor can be decreased when combined with Fedratinib.
Lasmiditan Lasmiditan The serum concentration of Fedratinib can be increased when it is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Fedratinib.
Tazemetostat Tazemetostat Fedratinib may decrease the excretion rate of Tazemetostat which could result in a higher serum level.
Bempedoic Acid Bempedoic Acid The excretion of Bempedoic acid can be decreased when combined with Fedratinib.
Cenobamate Cenobamate The serum concentration of Fedratinib can be decreased when it is combined with Cenobamate.
Ozanimod Ozanimod Fedratinib may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Selumetinib Selumetinib Fedratinib may decrease the excretion rate of Selumetinib which could result in a higher serum level.
Rimegepant Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Fedratinib.
Tucatinib Tucatinib Fedratinib may decrease the excretion rate of Tucatinib which could result in a higher serum level.
Remdesivir Injection Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Fedratinib.
Ripretinib Ripretinib Fedratinib may decrease the excretion rate of Ripretinib which could result in a higher serum level.
Lemborexant Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Fedratinib.
Fostemsavir Fostemsavir Fedratinib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Fedratinib.
Pralsetinib Pralsetinib The serum concentration of Pralsetinib can be increased when it is combined with Fedratinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Fedratinib can be decreased when it is combined with Satralizumab.
Relugolix Relugolix The serum concentration of Relugolix can be increased when it is combined with Fedratinib.
Theophylline Theophylline The metabolism of Theophylline can be decreased when combined with Fedratinib.
Indomethacin Indomethacin The metabolism of Fedratinib can be decreased when combined with Indomethacin.
Trazodone Trazodone The metabolism of Trazodone can be decreased when combined with Fedratinib.
Phenobarbital Phenobarbital The metabolism of Fedratinib can be decreased when combined with Phenobarbital.
Methotrexate Injection Methotrexate Injection Fedratinib may decrease the excretion rate of Methotrexate which could result in a higher serum level.
Primidone Primidone The metabolism of Fedratinib can be decreased when combined with Primidone.
Methsuximide Methsuximide The metabolism of Fedratinib can be decreased when combined with Methsuximide.
Chlorpromazine Chlorpromazine The metabolism of Chlorpromazine can be decreased when combined with Fedratinib.
Diazepam Diazepam The metabolism of Fedratinib can be decreased when combined with Diazepam.
Codeine Codeine The metabolism of Codeine can be decreased when combined with Fedratinib.
Tranylcypromine Tranylcypromine The metabolism of Fedratinib can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Fedratinib can be decreased when combined with Phenelzine.
Prochlorperazine Prochlorperazine The metabolism of Prochlorperazine can be decreased when combined with Fedratinib.
Thioridazine Thioridazine The metabolism of Fedratinib can be decreased when combined with Thioridazine.
Oxycodone Oxycodone The metabolism of Oxycodone can be decreased when combined with Fedratinib.
Methadone Methadone The metabolism of Fedratinib can be decreased when combined with Methadone.
Benztropine Benztropine The metabolism of Benzatropine can be decreased when combined with Fedratinib.
Maprotiline Maprotiline The metabolism of Maprotiline can be decreased when combined with Fedratinib.
Perphenazine Perphenazine The metabolism of Perphenazine can be decreased when combined with Fedratinib.
Amoxapine Amoxapine The metabolism of Amoxapine can be decreased when combined with Fedratinib.
Sulfasalazine Sulfasalazine Fedratinib may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Doxorubicin Doxorubicin The serum concentration of Doxorubicin can be increased when it is combined with Fedratinib.
Dactinomycin Dactinomycin The serum concentration of Dactinomycin can be increased when it is combined with Fedratinib.
Carbamazepine Carbamazepine The metabolism of Fedratinib can be decreased when combined with Carbamazepine.
Clonidine Clonidine The metabolism of Clonidine can be decreased when combined with Fedratinib.
Prazosin Prazosin Fedratinib may decrease the excretion rate of Prazosin which could result in a higher serum level.
Cimetidine Cimetidine The excretion of Cimetidine can be decreased when combined with Fedratinib.
Warfarin Warfarin The metabolism of Fedratinib can be decreased when combined with Warfarin.
Loperamide Loperamide The serum concentration of Fedratinib can be increased when it is combined with Loperamide.
Promethazine Promethazine The metabolism of Promethazine can be decreased when combined with Fedratinib.
Daunorubicin Daunorubicin Fedratinib may decrease the excretion rate of Daunorubicin which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Fedratinib may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Digoxin Digoxin Digoxin may decrease the excretion rate of Fedratinib which could result in a higher serum level.
Loxapine Loxapine The serum concentration of Fedratinib can be increased when it is combined with Loxapine.
Chloroquine Chloroquine The metabolism of Chloroquine can be decreased when combined with Fedratinib.
Quinine Quinine The serum concentration of Fedratinib can be increased when it is combined with Quinine.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Fedratinib.
Amitriptyline Amitriptyline The metabolism of Fedratinib can be decreased when combined with Amitriptyline.
Imipramine Imipramine The serum concentration of Fedratinib can be increased when it is combined with Imipramine.
Probenecid Probenecid The metabolism of Fedratinib can be decreased when combined with Probenecid.
Quinidine Quinidine The serum concentration of Fedratinib can be increased when it is combined with Quinidine.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Fedratinib.
Isoniazid Isoniazid The metabolism of Fedratinib can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Rifampicin can be increased when combined with Fedratinib.
Valproic Acid Valproic Acid The metabolism of Fedratinib can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Fedratinib.
Levothyroxine Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Fedratinib.
Liothyronine Liothyronine The therapeutic efficacy of Liothyronine can be decreased when used in combination with Fedratinib.
Methimazole Methimazole The therapeutic efficacy of Fedratinib can be decreased when used in combination with Methimazole.
Propylthiouracil Propylthiouracil The therapeutic efficacy of Propylthiouracil can be decreased when used in combination with Fedratinib.
Dextromethorphan Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Fedratinib.
Dinoprostone Dinoprostone The excretion of Dinoprostone can be decreased when combined with Fedratinib.
Chlorpheniramine Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Fedratinib.
Meclizine Meclizine The metabolism of Meclizine can be decreased when combined with Fedratinib.
Chlorzoxazone Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Fedratinib.
Carisoprodol Carisoprodol The metabolism of Fedratinib can be decreased when combined with Carisoprodol.
Folic Acid Folic Acid Fedratinib may decrease the excretion rate of Folic acid which could result in a higher serum level.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The metabolism of Fedratinib can be decreased when combined with Propranolol.
Nortriptyline Nortriptyline The serum concentration of Nortriptyline can be increased when it is combined with Fedratinib.
Nadolol Nadolol The excretion of Nadolol can be decreased when combined with Fedratinib.
Allopurinol Allopurinol Fedratinib may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Clomiphene Clomiphene The serum concentration of Clomifene can be increased when it is combined with Fedratinib.
Fluorouracil Injection Fluorouracil Injection Fedratinib may decrease the excretion rate of Fluorouracil which could result in a higher serum level.
Colchicine Colchicine The serum concentration of Colchicine can be increased when it is combined with Fedratinib.
Cephalexin Cephalexin The excretion of Fedratinib can be decreased when combined with Cephalexin.
Calcitonin Salmon Injection Calcitonin Salmon Injection The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Fedratinib.
Ketoconazole Ketoconazole The serum concentration of Fedratinib can be increased when it is combined with Ketoconazole.
Vincristine Injection Vincristine Injection The excretion of Vincristine can be decreased when combined with Fedratinib.
Vinblastine Vinblastine The serum concentration of Fedratinib can be increased when it is combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Metoprolol can be decreased when combined with Fedratinib.
Diltiazem Diltiazem The metabolism of Diltiazem can be decreased when combined with Fedratinib.
Nifedipine Nifedipine The metabolism of Nifedipine can be decreased when combined with Fedratinib.
Timolol Timolol The metabolism of Fedratinib can be decreased when combined with Timolol.
Verapamil Verapamil The serum concentration of Fedratinib can be increased when it is combined with Verapamil.
Atenolol Atenolol The metabolism of Atenolol can be decreased when combined with Fedratinib.
Pindolol Pindolol The metabolism of Pindolol can be decreased when combined with Fedratinib.
Etoposide Etoposide The serum concentration of Etoposide can be increased when it is combined with Fedratinib.
Glyburide Glyburide Fedratinib may decrease the excretion rate of Glyburide which could result in a higher serum level.
Pentamidine Injection Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Fedratinib.
Labetalol Labetalol The metabolism of Fedratinib can be decreased when combined with Labetalol.
Gemfibrozil Gemfibrozil The metabolism of Fedratinib can be decreased when combined with Gemfibrozil.
Pimozide Pimozide The metabolism of Pimozide can be decreased when combined with Fedratinib.
Enalapril Enalapril The excretion of Enalapril can be decreased when combined with Fedratinib.
Amiodarone Amiodarone The serum concentration of Fedratinib can be increased when it is combined with Amiodarone.
Buspirone Buspirone The metabolism of Buspirone can be decreased when combined with Fedratinib.
Lovastatin Lovastatin The excretion of Lovastatin can be decreased when combined with Fedratinib.
Ciprofloxacin Ciprofloxacin The excretion of Ciprofloxacin can be decreased when combined with Fedratinib.
Fluoxetine Fluoxetine The metabolism of Fedratinib can be decreased when combined with Fluoxetine.
Clozapine Clozapine The metabolism of Fedratinib can be decreased when combined with Clozapine.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Fedratinib.
Clarithromycin Clarithromycin The serum concentration of Fedratinib can be increased when it is combined with Clarithromycin.
Pravastatin Pravastatin Fedratinib may decrease the excretion rate of Pravastatin which could result in a higher serum level.
Simvastatin Simvastatin The serum concentration of Fedratinib can be increased when it is combined with Simvastatin.
Epoetin Alfa, Injection Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Fedratinib.
Teniposide Injection Teniposide Injection Fedratinib may decrease the excretion rate of Teniposide which could result in a higher serum level.
Itraconazole Itraconazole The serum concentration of Fedratinib can be increased when it is combined with Itraconazole.
Rifabutin Rifabutin The metabolism of Fedratinib can be increased when combined with Rifabutin.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Fedratinib.
Bisoprolol Bisoprolol The serum concentration of Fedratinib can be increased when it is combined with Bisoprolol.
Zolpidem Zolpidem The metabolism of Fedratinib can be decreased when combined with Zolpidem.
Doxazosin Doxazosin The metabolism of Fedratinib can be decreased when combined with Doxazosin.
Omeprazole Omeprazole The metabolism of Fedratinib can be decreased when combined with Omeprazole.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Fedratinib.
Venlafaxine Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Fedratinib.
Fluvoxamine Fluvoxamine The metabolism of Fedratinib can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Nefazodone can be decreased when combined with Fedratinib.
Losartan Losartan The metabolism of Fedratinib can be decreased when combined with Losartan.
Tramadol Tramadol The metabolism of Tramadol can be decreased when combined with Fedratinib.
Lansoprazole Lansoprazole The metabolism of Fedratinib can be decreased when combined with Lansoprazole.
Nicardipine Nicardipine The metabolism of Fedratinib can be decreased when combined with Nicardipine.
Ticlopidine Ticlopidine The metabolism of Fedratinib can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The serum concentration of Fedratinib can be increased when it is combined with Saquinavir.
Metformin Metformin The excretion of Metformin can be decreased when combined with Fedratinib.
Lamivudine Lamivudine Fedratinib may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole Riluzole Fedratinib may decrease the excretion rate of Riluzole which could result in a higher serum level.
Gemcitabine Injection Gemcitabine Injection The serum concentration of Gemcitabine can be increased when it is combined with Fedratinib.
Ritonavir Ritonavir The serum concentration of Fedratinib can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The excretion of Docetaxel can be decreased when combined with Fedratinib.
Clomipramine Clomipramine The metabolism of Fedratinib can be decreased when combined with Clomipramine.
Zafirlukast Zafirlukast The metabolism of Fedratinib can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine The metabolism of Mirtazapine can be decreased when combined with Fedratinib.
Topiramate Topiramate The metabolism of Fedratinib can be decreased when combined with Topiramate.
Valsartan Valsartan The excretion of Valsartan can be decreased when combined with Fedratinib.
Donepezil Donepezil Fedratinib may decrease the excretion rate of Donepezil which could result in a higher serum level.
Fexofenadine Fexofenadine The serum concentration of Fedratinib can be increased when it is combined with Fexofenadine.
Carvedilol Carvedilol The serum concentration of Fedratinib can be increased when it is combined with Carvedilol.
Nilutamide Nilutamide The metabolism of Fedratinib can be decreased when combined with Nilutamide.
Selegiline Selegiline The metabolism of Selegiline can be decreased when combined with Fedratinib.
Bicalutamide Bicalutamide The metabolism of Fedratinib can be decreased when combined with Bicalutamide.
Sertraline Sertraline The metabolism of Fedratinib can be decreased when combined with Sertraline.
Propafenone Propafenone The serum concentration of Fedratinib can be increased when it is combined with Propafenone.
Letrozole Letrozole The metabolism of Fedratinib can be decreased when combined with Letrozole.
Raloxifene Raloxifene Fedratinib may decrease the excretion rate of Raloxifene which could result in a higher serum level.
Tamsulosin Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Fedratinib.
Quetiapine Quetiapine The metabolism of Quetiapine can be decreased when combined with Fedratinib.
Paroxetine Paroxetine The metabolism of Fedratinib can be decreased when combined with Paroxetine.
Citalopram Citalopram The metabolism of Fedratinib can be decreased when combined with Citalopram.
Efavirenz Efavirenz The metabolism of Fedratinib can be decreased when combined with Efavirenz.
Sildenafil Sildenafil The serum concentration of Fedratinib can be increased when it is combined with Sildenafil.
Celecoxib Celecoxib Fedratinib may decrease the excretion rate of Celecoxib which could result in a higher serum level.
Tolterodine Tolterodine The metabolism of Tolterodine can be decreased when combined with Fedratinib.
Thalidomide Thalidomide The metabolism of Fedratinib can be decreased when combined with Thalidomide.
Nateglinide Nateglinide The metabolism of Nateglinide can be decreased when combined with Fedratinib.
Galantamine Galantamine The metabolism of Galantamine can be decreased when combined with Fedratinib.
Rabeprazole Rabeprazole The metabolism of Fedratinib can be decreased when combined with Rabeprazole.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists

Still Confused? Ask the pharmacist a question here!