Felbamate

Generic name: Pronounced as (fel bam' ate)
Brand names
  • Felbatol®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 05/15/2020

Felbamate may cause a serious blood condition called aplastic anemia. Symptoms of aplastic anemia can start any time you are taking felbamate or for a period of time after you stop taking felbamate. Tell your doctor if you have or have ever had blood problems. Your doctor will probably tell you not to take felbamate. If you experience any of the following symptoms while taking felbamate or after you stop taking felbamate, call your doctor immediately: fever, sore throat, chills, other signs of infection, bleeding, easy bruising, extreme tiredness, weakness, or lack of energy.

Felbamate may cause liver damage. Tell your doctor if you have or have ever had liver disease. Your doctor will probably tell you not to take felbamate. If you experience any of the following symptoms, call your doctor immediately: nausea, extreme tiredness, unusual bleeding or bruising, lack of energy, loss of appetite, pain in the upper right part of the stomach, yellowing of the skin or eyes, or flu-like symptoms.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests before, during, and after treatment to check your body's response to felbamate.

Talk to your doctor about the risks of taking felbamate. You will have to sign an informed consent form before you start taking felbamate.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with felbamate and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.

Felbamate is used to treat certain seizures in adults and children with epilepsy whose seizures have not improved with other treatments. It is used alone or in combination with other medications to treat partial seizures in adults. It is used in combination with other medications to treat partial and generalized seizures in children with Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Felbamate is in a class of medications called anticonvulsants. It works by decreasing abnormal activity in the brain.

Felbamate comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken with or without food three or four times a day. Take felbamate at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take felbamate exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well before each use to mix the medication evenly.

Your doctor will probably start you on a low dose of felbamate and gradually increase your dose every one or two weeks.

Felbamate controls seizures but does not cure them. Continue to take felbamate even if you feel well. Do not stop taking felbamate without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood. If you suddenly stop taking felbamate, your seizures may become worse. Your doctor will probably decrease your dose gradually.

This medication should not be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking felbamate,

  • tell your doctor and pharmacist if you are allergic to felbamate; carbamate medications such as meprobamate (Miltown), methocarbamol (Robaxin), and rivastigmine (Exelon); or any other medications.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: carbamazepine (Tegretol), clopidogrel (Plavix); phenobarbital (Luminal, Solfoton), phenytoin (Dilantin), oral contraceptives (birth control pills), and valproate (Depacon). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have or have ever had any of the conditions listed in the IMPORTANT WARNINGS section or kidney disease.

  • tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking felbamate, call your doctor.

  • tell your doctor if you are breastfeeding. Do not breastfeed while taking felbamate.

  • you should know that felbamate may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.

  • remember that alcohol can add to the drowsiness caused by this medication.

  • you should know that your mental health may change in unexpected ways and you may become suicidal (thinking about harming or killing yourself or planning or trying to do so) while you are taking felbamate for the treatment of epilepsy, mental illness, or other conditions. A small number of adults and children 5 years of age and older (about 1 in 500 people) who took anticonvulsants such as felbamate to treat various conditions during clinical studies became suicidal during their treatment. Some of these people developed suicidal thoughts and behavior as early as one week after they started taking the medication. There is a risk that you may experience changes in your mental health if you take an anticonvulsant medication such as felbamate, but there may also be a risk that you will experience changes in your mental health if your condition is not treated. You and your doctor will decide whether the risks of taking an anticonvulsant medication are greater than the risks of not taking the medication. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: panic attacks; agitation or restlessness; new or worsening irritability, anxiety, or depression; acting on dangerous impulses; difficulty falling or staying asleep; aggressive, angry, or violent behavior; mania (frenzied, abnormally excited mood); talking or thinking about wanting to hurt yourself or end your life; withdrawing from friends and family; preoccupation with death and dying; giving away prized possessions; or any other unusual changes in behavior or mood. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Felbamate may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • heartburn

    • vomiting

    • constipation

    • diarrhea

    • weight loss

    • difficulty falling asleep or staying asleep

    • nervousness

    • drowsiness

    • swelling of the face

    • runny nose

    • differences in menstrual bleeding

  • Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:

    • hives

    • rash

    • itching

    • difficulty breathing or swallowing

    • rapid or pounding heartbeat

  • Felbamate may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

  • nausea

  • rapid heartbeat

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The risk or severity of QTc prolongation can be increased when Felbamate is combined with Moxifloxacin.
Montelukast Montelukast The metabolism of Montelukast can be decreased when combined with Felbamate.
Leflunomide Leflunomide The metabolism of Leflunomide can be decreased when combined with Felbamate.
Nevirapine Nevirapine The metabolism of Nevirapine can be decreased when combined with Felbamate.
Dolasetron Dolasetron The risk or severity of QTc prolongation can be increased when Felbamate is combined with Dolasetron.
Aminophylline Aminophylline The metabolism of Aminophylline can be increased when combined with Felbamate.
Anagrelide Anagrelide The risk or severity of QTc prolongation can be increased when Felbamate is combined with Anagrelide.
Candesartan Candesartan The metabolism of Candesartan can be decreased when combined with Felbamate.
Cilostazol Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Felbamate.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Felbamate.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Felbamate is combined with Diphenoxylate.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The risk or severity of QTc prolongation can be increased when Felbamate is combined with Erythromycin.
Fenofibrate Fenofibrate The metabolism of Fenofibrate can be increased when combined with Felbamate.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Felbamate is combined with Guanfacine.
Naratriptan Naratriptan The risk or severity of adverse effects can be increased when Felbamate is combined with Naratriptan.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Felbamate.
Penbutolol Penbutolol The risk or severity of QTc prolongation can be increased when Felbamate is combined with Acebutolol.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Felbamate.
Reserpine Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Felbamate.
Rizatriptan Rizatriptan The risk or severity of adverse effects can be increased when Felbamate is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Sumatriptan is combined with Felbamate.
Tacrolimus Tacrolimus The metabolism of Tacrolimus can be increased when combined with Felbamate.
Tizanidine Tizanidine The risk or severity of adverse effects can be increased when Tizanidine is combined with Felbamate.
Zolmitriptan Zolmitriptan The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Felbamate.
Famotidine Injection Famotidine Injection The risk or severity of QTc prolongation can be increased when Famotidine is combined with Felbamate.
Fluconazole Injection Fluconazole Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Felbamate.
Foscarnet Injection Foscarnet Injection The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Felbamate.
Hydromorphone Injection Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Felbamate.
Levofloxacin Injection Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Felbamate is combined with Levofloxacin.
Meperidine Injection Meperidine Injection The risk or severity of adverse effects can be increased when Meperidine is combined with Felbamate.
Metoclopramide Injection Metoclopramide Injection The risk or severity of sedation can be increased when Felbamate is combined with Metoclopramide.
Metronidazole Injection Metronidazole Injection The therapeutic efficacy of Felbamate can be decreased when used in combination with Metronidazole.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Felbamate.
Zidovudine Injection Zidovudine Injection The metabolism of Zidovudine can be decreased when combined with Felbamate.
Altretamine Altretamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Felbamate.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be increased when combined with Felbamate.
Ondansetron Ondansetron The risk or severity of QTc prolongation can be increased when Felbamate is combined with Ondansetron.
Granisetron Granisetron The risk or severity of QTc prolongation can be increased when Felbamate is combined with Granisetron.
Torsemide Torsemide The metabolism of Torasemide can be decreased when combined with Felbamate.
Olanzapine Olanzapine The risk or severity of adverse effects can be increased when Olanzapine is combined with Felbamate.
Alosetron Alosetron The metabolism of Alosetron can be decreased when combined with Felbamate.
Dofetilide Dofetilide The metabolism of Dofetilide can be increased when combined with Felbamate.
Entacapone Entacapone The risk or severity of adverse effects can be increased when Entacapone is combined with Felbamate.
Hydroxychloroquine Hydroxychloroquine The therapeutic efficacy of Hydroxychloroquine can be decreased when used in combination with Felbamate.
Meloxicam Meloxicam The metabolism of Meloxicam can be decreased when combined with Felbamate.
Orlistat Orlistat Orlistat can cause a decrease in the absorption of Felbamate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Oxcarbazepine Oxcarbazepine The risk or severity of adverse effects can be increased when Oxcarbazepine is combined with Felbamate.
Pantoprazole Pantoprazole The metabolism of Pantoprazole can be decreased when combined with Felbamate.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Felbamate is combined with Zaleplon.
Anakinra Anakinra The metabolism of Felbamate can be increased when combined with Anakinra.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Felbamate is combined with Desloratadine.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Felbamate.
Trimipramine Trimipramine The metabolism of Trimipramine can be decreased when combined with Felbamate.
Etanercept Injection Etanercept Injection The metabolism of Felbamate can be increased when combined with Etanercept.
Glycopyrrolate Glycopyrrolate Felbamate may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Tenofovir Tenofovir The metabolism of Tenofovir can be increased when combined with Felbamate.
Sirolimus Sirolimus The metabolism of Sirolimus can be increased when combined with Felbamate.
Escitalopram Escitalopram The risk or severity of adverse effects can be increased when Felbamate is combined with Escitalopram.
Zonisamide Zonisamide The risk or severity of adverse effects can be increased when Zonisamide is combined with Felbamate.
Adalimumab Injection Adalimumab Injection The metabolism of Felbamate can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be increased when combined with Felbamate.
Atomoxetine Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Felbamate.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Felbamate is combined with Dexmethylphenidate.
Atazanavir Atazanavir The metabolism of Atazanavir can be increased when combined with Felbamate.
Almotriptan Almotriptan The risk or severity of adverse effects can be increased when Almotriptan is combined with Felbamate.
Eletriptan Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Felbamate.
Mefloquine Mefloquine The therapeutic efficacy of Felbamate can be decreased when used in combination with Mefloquine.
Rosuvastatin Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Felbamate.
Vardenafil Vardenafil The risk or severity of QTc prolongation can be increased when Vardenafil is combined with Felbamate.
Alfuzosin Alfuzosin The risk or severity of QTc prolongation can be increased when Alfuzosin is combined with Felbamate.
Memantine Memantine The risk or severity of adverse effects can be increased when Felbamate is combined with Memantine.
Tegaserod Tegaserod The metabolism of Felbamate can be decreased when combined with Tegaserod.
Frovatriptan Frovatriptan The risk or severity of adverse effects can be increased when Felbamate is combined with Frovatriptan.
Gemifloxacin Gemifloxacin The risk or severity of QTc prolongation can be increased when Felbamate is combined with Gemifloxacin.
Progesterone Progesterone The metabolism of Progesterone can be increased when combined with Felbamate.
Apomorphine Injection Apomorphine Injection The risk or severity of adverse effects can be increased when Apomorphine is combined with Felbamate.
Infliximab Injection Infliximab Injection The metabolism of Felbamate can be increased when combined with Infliximab.
Protriptyline Protriptyline The risk or severity of adverse effects can be increased when Protriptyline is combined with Felbamate.
Duloxetine Duloxetine The risk or severity of adverse effects can be increased when Felbamate is combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Norethisterone can be increased when combined with Felbamate.
Trospium Trospium Felbamate may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Bosentan Bosentan The metabolism of Bosentan can be decreased when combined with Felbamate.
Erlotinib Erlotinib The serum concentration of Erlotinib can be decreased when it is combined with Felbamate.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Felbamate is combined with Eszopiclone.
Ganciclovir Ganciclovir The therapeutic efficacy of Felbamate can be decreased when used in combination with Ganciclovir.
Solifenacin Solifenacin Felbamate may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Valganciclovir Valganciclovir The therapeutic efficacy of Felbamate can be decreased when used in combination with Valganciclovir.
Voriconazole Voriconazole The metabolism of Voriconazole can be decreased when combined with Felbamate.
Dextroamphetamine Dextroamphetamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Felbamate.
Sodium Oxybate Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Felbamate.
Ibandronate Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Felbamate.
Isocarboxazid Isocarboxazid The risk or severity of adverse effects can be increased when Felbamate is combined with Isocarboxazid.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Felbamate.
Darifenacin Darifenacin Felbamate may increase the central nervous system depressant (CNS depressant) activities of Darifenacin.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Fentanyl is combined with Felbamate.
Pregabalin Pregabalin The therapeutic efficacy of Felbamate can be increased when used in combination with Pregabalin.
Ranolazine Ranolazine The metabolism of Ranolazine can be increased when combined with Felbamate.
Abatacept Injection Abatacept Injection The metabolism of Felbamate can be increased when combined with Abatacept.
Rasagiline Rasagiline The risk or severity of adverse effects can be increased when Felbamate is combined with Rasagiline.
Imatinib Imatinib The metabolism of Imatinib can be decreased when combined with Felbamate.
Albuterol Albuterol The risk or severity of QTc prolongation can be increased when Felbamate is combined with Salbutamol.
Paliperidone Paliperidone The risk or severity of QTc prolongation can be increased when Felbamate is combined with Paliperidone.
Bortezomib Bortezomib The metabolism of Bortezomib can be increased when combined with Felbamate.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Felbamate is combined with Oxaliplatin.
Posaconazole Posaconazole The risk or severity of QTc prolongation can be increased when Felbamate is combined with Posaconazole.
Primaquine Primaquine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Primaquine.
Dimenhydrinate Dimenhydrinate The risk or severity of adverse effects can be increased when Felbamate is combined with Dimenhydrinate.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Felbamate.
Retapamulin Retapamulin The metabolism of Retapamulin can be increased when combined with Felbamate.
Vorinostat Vorinostat The risk or severity of QTc prolongation can be increased when Felbamate is combined with Vorinostat.
Sorafenib Sorafenib The metabolism of Felbamate can be increased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Sunitinib can be increased when combined with Felbamate.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Felbamate.
Lapatinib Lapatinib The metabolism of Lapatinib can be decreased when combined with Felbamate.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Felbamate is combined with Levocetirizine.
Dasatinib Dasatinib The metabolism of Dasatinib can be increased when combined with Felbamate.
Temsirolimus Temsirolimus The metabolism of Temsirolimus can be increased when combined with Felbamate.
Nilotinib Nilotinib The metabolism of Nilotinib can be increased when combined with Felbamate.
Toremifene Toremifene The risk or severity of QTc prolongation can be increased when Felbamate is combined with Toremifene.
Bexarotene Bexarotene The metabolism of Bexarotene can be decreased when combined with Felbamate.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Felbamate.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Felbamate.
Etravirine Etravirine The metabolism of Etravirine can be decreased when combined with Felbamate.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Felbamate is combined with Arsenic trioxide.
Mitoxantrone Injection Mitoxantrone Injection The metabolism of Felbamate can be increased when combined with Mitoxantrone.
Desvenlafaxine Desvenlafaxine The risk or severity of adverse effects can be increased when Felbamate is combined with Desvenlafaxine.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Felbamate.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Felbamate.
Flecainide Flecainide The risk or severity of QTc prolongation can be increased when Felbamate is combined with Flecainide.
Certolizumab Injection Certolizumab Injection The metabolism of Felbamate can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The metabolism of Ixabepilone can be increased when combined with Felbamate.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be increased when combined with Felbamate.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Felbamate.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Felbamate.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Midazolam is combined with Felbamate.
Milnacipran Milnacipran The metabolism of Milnacipran can be increased when combined with Felbamate.
Dexlansoprazole Dexlansoprazole The metabolism of Dexlansoprazole can be decreased when combined with Felbamate.
Sodium Phosphate Sodium Phosphate The therapeutic efficacy of Felbamate can be decreased when used in combination with Sodium phosphate, monobasic.
Fesoterodine Fesoterodine Felbamate may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Degarelix Injection Degarelix Injection The risk or severity of QTc prolongation can be increased when Felbamate is combined with Degarelix.
Betaxolol Betaxolol The risk or severity of QTc prolongation can be increased when Felbamate is combined with Betaxolol.
Iloperidone Iloperidone The risk or severity of QTc prolongation can be increased when Felbamate is combined with Iloperidone.
Prasugrel Prasugrel The metabolism of Prasugrel can be decreased when combined with Felbamate.
Lacosamide Lacosamide The metabolism of Lacosamide can be decreased when combined with Felbamate.
Everolimus Everolimus The metabolism of Everolimus can be increased when combined with Felbamate.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be increased when combined with Felbamate.
Dronedarone Dronedarone The metabolism of Dronedarone can be increased when combined with Felbamate.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Felbamate.
Palonosetron Injection Palonosetron Injection The risk or severity of adverse effects can be increased when Palonosetron is combined with Felbamate.
Telavancin Injection Telavancin Injection The risk or severity of QTc prolongation can be increased when Felbamate is combined with Telavancin.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be increased when combined with Felbamate.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Felbamate.
Topotecan Topotecan Felbamate may increase the excretion rate of Topotecan which could result in a lower serum level and potentially a reduction in efficacy.
Golimumab Injection Golimumab Injection The metabolism of Felbamate can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Pazopanib can be increased when combined with Felbamate.
Asenapine Asenapine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Asenapine.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Felbamate is combined with Vigabatrin.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Felbamate.
Albendazole Albendazole The metabolism of Albendazole can be decreased when combined with Felbamate.
Ulipristal Ulipristal The metabolism of Ulipristal can be increased when combined with Felbamate.
Levonorgestrel Levonorgestrel The metabolism of Levonorgestrel can be increased when combined with Felbamate.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Felbamate is combined with Oxymorphone.
Tocilizumab Injection Tocilizumab Injection The metabolism of Felbamate can be increased when combined with Tocilizumab.
Fingolimod Fingolimod The metabolism of Fingolimod can be decreased when combined with Felbamate.
Eribulin Injection Eribulin Injection The risk or severity of QTc prolongation can be increased when Felbamate is combined with Eribulin.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Felbamate.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be increased when combined with Felbamate.
Lurasidone Lurasidone The risk or severity of adverse effects can be increased when Felbamate is combined with Lurasidone.
Acetaminophen Injection Acetaminophen Injection Acetaminophen may increase the hepatotoxic activities of Felbamate.
Vilazodone Vilazodone The risk or severity of adverse effects can be increased when Felbamate is combined with Vilazodone.
Denileukin Diftitox Injection Denileukin Diftitox Injection The metabolism of Felbamate can be decreased when combined with Aldesleukin.
Terbutaline Injection Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Felbamate.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be increased when combined with Felbamate.
Roflumilast Roflumilast The metabolism of Roflumilast can be increased when combined with Felbamate.
Linagliptin Linagliptin The metabolism of Linagliptin can be increased when combined with Felbamate.
Rilpivirine Rilpivirine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Rilpivirine.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be increased when combined with Felbamate.
Triptorelin Injection Triptorelin Injection The risk or severity of QTc prolongation can be increased when Felbamate is combined with Triptorelin.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be increased when combined with Felbamate.
Ruxolitinib Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Felbamate.
Vandetanib Vandetanib The metabolism of Vandetanib can be increased when combined with Felbamate.
Clobazam Clobazam The risk or severity of adverse effects can be increased when Clobazam is combined with Felbamate.
Vemurafenib Vemurafenib The risk or severity of QTc prolongation can be increased when Felbamate is combined with Vemurafenib.
Vismodegib Vismodegib The metabolism of Vismodegib can be decreased when combined with Felbamate.
Axitinib Axitinib The metabolism of Axitinib can be increased when combined with Felbamate.
Crizotinib Crizotinib The metabolism of Crizotinib can be increased when combined with Felbamate.
Cabergoline Cabergoline The metabolism of Felbamate can be increased when combined with Cabergoline.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Tiagabine is combined with Felbamate.
Enzalutamide Enzalutamide The metabolism of Enzalutamide can be decreased when combined with Felbamate.
Mirabegron Mirabegron The risk or severity of QTc prolongation can be increased when Felbamate is combined with Mirabegron.
Regorafenib Regorafenib The metabolism of Regorafenib can be increased when combined with Felbamate.
Bosutinib Bosutinib The metabolism of Bosutinib can be increased when combined with Felbamate.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Felbamate.
Bedaquiline Bedaquiline The risk or severity of QTc prolongation can be increased when Felbamate is combined with Bedaquiline.
Ponatinib Ponatinib The metabolism of Ponatinib can be increased when combined with Felbamate.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be increased when combined with Felbamate.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be increased when combined with Felbamate.
Apixaban Apixaban The metabolism of Apixaban can be decreased when combined with Felbamate.
Dabrafenib Dabrafenib The metabolism of Dabrafenib can be increased when combined with Felbamate.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Felbamate.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Felbamate.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Felbamate.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Felbamate.
Lomitapide Lomitapide The metabolism of Lomitapide can be increased when combined with Felbamate.
Ketorolac Injection Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Felbamate.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Felbamate.
Apremilast Apremilast The metabolism of Felbamate can be increased when combined with Apremilast.
Ceritinib Ceritinib The metabolism of Ceritinib can be increased when combined with Felbamate.
Siltuximab Injection Siltuximab Injection The metabolism of Felbamate can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Felbamate is combined with Eslicarbazepine.
Idelalisib Idelalisib The metabolism of Idelalisib can be increased when combined with Felbamate.
Testosterone Injection Testosterone Injection The metabolism of Testosterone can be decreased when combined with Felbamate.
Vorapaxar Vorapaxar The metabolism of Vorapaxar can be increased when combined with Felbamate.
Hydrocodone Hydrocodone Felbamate may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Suvorexant Suvorexant Felbamate may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Olaparib Olaparib The metabolism of Olaparib can be increased when combined with Felbamate.
Methamphetamine Methamphetamine The risk or severity of adverse effects can be increased when Felbamate is combined with Metamfetamine.
Tasimelteon Tasimelteon The risk or severity of adverse effects can be increased when Felbamate is combined with Tasimelteon.
Nintedanib Nintedanib The metabolism of Nintedanib can be increased when combined with Felbamate.
Secukinumab Injection Secukinumab Injection The metabolism of Felbamate can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The risk or severity of adverse effects can be increased when Risperidone is combined with Felbamate.
Palbociclib Palbociclib The metabolism of Palbociclib can be increased when combined with Felbamate.
Lenvatinib Lenvatinib The risk or severity of QTc prolongation can be increased when Felbamate is combined with Lenvatinib.
Panobinostat Panobinostat The metabolism of Panobinostat can be increased when combined with Felbamate.
Haloperidol Injection Haloperidol Injection The risk or severity of QTc prolongation can be increased when Felbamate is combined with Haloperidol.
Ivabradine Ivabradine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Ivabradine.
Sonidegib Sonidegib The metabolism of Sonidegib can be increased when combined with Felbamate.
Flibanserin Flibanserin The risk or severity of adverse effects can be increased when Felbamate is combined with Flibanserin.
Brexpiprazole Brexpiprazole The risk or severity of adverse effects can be increased when Felbamate is combined with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Felbamate is combined with Ziprasidone.
Cariprazine Cariprazine The risk or severity of adverse effects can be increased when Felbamate is combined with Cariprazine.
Cobimetinib Cobimetinib The metabolism of Cobimetinib can be increased when combined with Felbamate.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Felbamate.
Osimertinib Osimertinib The metabolism of Felbamate can be increased when combined with Osimertinib.
Alectinib Alectinib The metabolism of Alectinib can be increased when combined with Felbamate.
Ixazomib Ixazomib The metabolism of Ixazomib can be increased when combined with Felbamate.
Lesinurad Lesinurad The metabolism of Lesinurad can be decreased when combined with Felbamate.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The therapeutic efficacy of Felbamate can be decreased when used in combination with Amphotericin B.
Dexamethasone Injection Dexamethasone Injection The metabolism of Felbamate can be increased when combined with Dexamethasone.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Felbamate.
Venetoclax Venetoclax The metabolism of Venetoclax can be increased when combined with Felbamate.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Felbamate is combined with Pimavanserin.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Felbamate.
Ribociclib Ribociclib The risk or severity of QTc prolongation can be increased when Felbamate is combined with Ribociclib.
Brigatinib Brigatinib The metabolism of Brigatinib can be increased when combined with Felbamate.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Felbamate.
Deutetrabenazine Deutetrabenazine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Deutetrabenazine.
Safinamide Safinamide The risk or severity of adverse effects can be increased when Felbamate is combined with Safinamide.
Midostaurin Midostaurin The metabolism of Felbamate can be increased when combined with Midostaurin.
Neratinib Neratinib The metabolism of Neratinib can be increased when combined with Felbamate.
Enasidenib Enasidenib The metabolism of Enasidenib can be increased when combined with Felbamate.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Felbamate.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Felbamate.
Delafloxacin Delafloxacin The risk or severity of QTc prolongation can be increased when Delafloxacin is combined with Felbamate.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be increased when combined with Felbamate.
Acalabrutinib Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Felbamate.
Tetrabenazine Tetrabenazine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Tetrabenazine.
Buprenorphine Injection Buprenorphine Injection Felbamate may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Baricitinib Baricitinib The metabolism of Baricitinib can be increased when combined with Felbamate.
Lofexidine Lofexidine The therapeutic efficacy of Felbamate can be increased when used in combination with Lofexidine.
Eliglustat Eliglustat The risk or severity of QTc prolongation can be increased when Felbamate is combined with Eliglustat.
Encorafenib Encorafenib The risk or severity of QTc prolongation can be increased when Felbamate is combined with Encorafenib.
Ivosidenib Ivosidenib The metabolism of Ivosidenib can be increased when combined with Felbamate.
Cannabidiol Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Felbamate.
Dacomitinib Dacomitinib The metabolism of Dacomitinib can be increased when combined with Felbamate.
Duvelisib Duvelisib The metabolism of Duvelisib can be increased when combined with Felbamate.
Stiripentol Stiripentol The risk or severity of adverse effects can be increased when Felbamate is combined with Stiripentol.
Gilteritinib Gilteritinib The risk or severity of QTc prolongation can be increased when Felbamate is combined with Gilteritinib.
Glasdegib Glasdegib The risk or severity of QTc prolongation can be increased when Felbamate is combined with Glasdegib.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Felbamate.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Felbamate.
Prucalopride Prucalopride The metabolism of Prucalopride can be increased when combined with Felbamate.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Felbamate can be increased when combined with Emapalumab.
Siponimod Siponimod The risk or severity of adverse effects can be increased when Felbamate is combined with Siponimod.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be increased when combined with Felbamate.
Esomeprazole Injection Esomeprazole Injection The metabolism of Esomeprazole can be decreased when combined with Felbamate.
Alpelisib Alpelisib The metabolism of Alpelisib can be increased when combined with Felbamate.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Felbamate is combined with Brexanolone.
Solriamfetol Solriamfetol The risk or severity of adverse effects can be increased when Felbamate is combined with Solriamfetol.
Triclabendazole Triclabendazole The metabolism of Triclabendazole can be decreased when combined with Felbamate.
Entrectinib Entrectinib The risk or severity of QTc prolongation can be increased when Felbamate is combined with Entrectinib.
Pexidartinib Pexidartinib The metabolism of Pexidartinib can be increased when combined with Felbamate.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Felbamate.
Pitolisant Pitolisant The serum concentration of Felbamate can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The metabolism of Fedratinib can be decreased when combined with Felbamate.
Lefamulin Lefamulin Lefamulin may increase the QTc-prolonging activities of Felbamate.
Phenytoin Injection Phenytoin Injection The serum concentration of Phenytoin can be increased when it is combined with Felbamate.
Fosphenytoin Injection Fosphenytoin Injection The serum concentration of Fosphenytoin can be increased when it is combined with Felbamate.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Felbamate.
Voxelotor Voxelotor The metabolism of Voxelotor can be decreased when combined with Felbamate.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Felbamate.
Lumateperone Lumateperone The serum concentration of Lumateperone can be decreased when it is combined with Felbamate.
Lasmiditan Lasmiditan The risk or severity of adverse effects can be increased when Felbamate is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be decreased when it is combined with Felbamate.
Tazemetostat Tazemetostat The metabolism of Tazemetostat can be increased when combined with Felbamate.
Cenobamate Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Felbamate.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Felbamate.
Rimegepant Rimegepant The metabolism of Rimegepant can be increased when combined with Felbamate.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Felbamate.
Selpercatinib Selpercatinib The serum concentration of Selpercatinib can be decreased when it is combined with Felbamate.
Capmatinib Capmatinib The serum concentration of Capmatinib can be decreased when it is combined with Felbamate.
Lemborexant Lemborexant The serum concentration of Lemborexant can be decreased when it is combined with Felbamate.
Fenfluramine Fenfluramine The risk or severity of adverse effects can be increased when Fenfluramine is combined with Felbamate.
Fostemsavir Fostemsavir The risk or severity of QTc prolongation can be increased when Felbamate is combined with Fostemsavir.
Octreotide Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Felbamate.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Felbamate can be decreased when it is combined with Satralizumab.
Relugolix Relugolix The risk or severity of QTc prolongation can be increased when Felbamate is combined with Relugolix.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be increased when combined with Felbamate.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Felbamate is combined with Viloxazine.
Theophylline Theophylline The metabolism of Theophylline can be increased when combined with Felbamate.
Indomethacin Indomethacin The metabolism of Indomethacin can be decreased when combined with Felbamate.
Mefenamic Acid Mefenamic Acid The metabolism of Mefenamic acid can be decreased when combined with Felbamate.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Felbamate.
Trazodone Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Felbamate.
Phenobarbital Phenobarbital The serum concentration of Phenobarbital, an active metabolite of Phenobarbital, can be increased when used in combination with Felbamate.
Metaxalone Metaxalone The risk or severity of adverse effects can be increased when Metaxalone is combined with Felbamate.
Methotrexate Injection Methotrexate Injection The metabolism of Methotrexate can be increased when combined with Felbamate.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Levorphanol is combined with Felbamate.
Primidone Primidone The serum concentration of Phenobarbital, an active metabolite of Primidone, can be increased when used in combination with Felbamate.
Methsuximide Methsuximide The risk or severity of adverse effects can be increased when Felbamate is combined with Methsuximide.
Diethylpropion Diethylpropion The risk or severity of adverse effects can be increased when Diethylpropion is combined with Felbamate.
Chlorpromazine Chlorpromazine The risk or severity of adverse effects can be increased when Chlorpromazine is combined with Felbamate.
Diazepam Diazepam The metabolism of Diazepam can be decreased when combined with Felbamate.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Oxazepam is combined with Felbamate.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Flurazepam is combined with Felbamate.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Clorazepic acid is combined with Felbamate.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Felbamate.
Amantadine Amantadine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Felbamate.
Codeine Codeine The risk or severity of adverse effects can be increased when Codeine is combined with Felbamate.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Felbamate.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Felbamate.
Bromocriptine Bromocriptine The risk or severity of adverse effects can be increased when Felbamate is combined with Bromocriptine.
Tranylcypromine Tranylcypromine The risk or severity of adverse effects can be increased when Tranylcypromine is combined with Felbamate.
Phenelzine Phenelzine The risk or severity of adverse effects can be increased when Phenelzine is combined with Felbamate.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Felbamate is combined with Procarbazine.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of adverse effects can be increased when Felbamate is combined with Ergoloid mesylate.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Felbamate.
Prochlorperazine Prochlorperazine The risk or severity of adverse effects can be increased when Prochlorperazine is combined with Felbamate.
Thioridazine Thioridazine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Thioridazine.
Trifluoperazine Trifluoperazine The risk or severity of adverse effects can be increased when Trifluoperazine is combined with Felbamate.
Dapsone Dapsone The metabolism of Dapsone can be decreased when combined with Felbamate.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Felbamate.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Felbamate.
Oxybutynin Oxybutynin Felbamate may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin.
Benztropine Benztropine Felbamate may increase the central nervous system depressant (CNS depressant) activities of Benzatropine.
Maprotiline Maprotiline Felbamate may increase the central nervous system depressant (CNS depressant) activities of Maprotiline.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Felbamate.
Trihexyphenidyl Trihexyphenidyl Felbamate may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine Orphenadrine Felbamate may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The risk or severity of adverse effects can be increased when Perphenazine is combined with Felbamate.
Fluphenazine Fluphenazine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Felbamate.
Phentermine Phentermine The metabolism of Phentermine can be increased when combined with Felbamate.
Methylphenidate Methylphenidate The therapeutic efficacy of Felbamate can be decreased when used in combination with Methylphenidate.
Amoxapine Amoxapine Felbamate may increase the central nervous system depressant (CNS depressant) activities of Amoxapine.
Doxorubicin Doxorubicin The metabolism of Doxorubicin can be increased when combined with Felbamate.
Carbamazepine Carbamazepine The serum concentration of Felbamate can be decreased when it is combined with Carbamazepine.
Molindone Molindone The risk or severity of adverse effects can be increased when Felbamate is combined with Molindone.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Felbamate.
Cimetidine Cimetidine The metabolism of Felbamate can be decreased when combined with Cimetidine.
Warfarin Warfarin The metabolism of Warfarin can be increased when combined with Felbamate.
Clonazepam Clonazepam The metabolism of Clonazepam can be increased when combined with Felbamate.
Loperamide Loperamide The risk or severity of QTc prolongation can be increased when Felbamate is combined with Loperamide.
Promethazine Promethazine The risk or severity of adverse effects can be increased when Felbamate is combined with Promethazine.
Digoxin Digoxin The risk or severity of QTc prolongation can be increased when Digoxin is combined with Felbamate.
Loxapine Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Felbamate.
Chloroquine Chloroquine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Chloroquine.
Quinine Quinine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Quinine.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Ethosuximide is combined with Felbamate.
Isosorbide Isosorbide The metabolism of Isosorbide can be increased when combined with Felbamate.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Felbamate.
Secobarbital Secobarbital The serum concentration of Secobarbital can be increased when it is combined with Felbamate.
Desipramine Desipramine Felbamate may increase the central nervous system depressant (CNS depressant) activities of Desipramine.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Felbamate.
Imipramine Imipramine The metabolism of Imipramine can be decreased when combined with Felbamate.
Quinidine Quinidine The metabolism of Quinidine can be increased when combined with Felbamate.
Procainamide Procainamide The risk or severity of QTc prolongation can be increased when Felbamate is combined with Procainamide.
Isoniazid Isoniazid The metabolism of Felbamate can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Felbamate can be increased when combined with Rifampicin.
Disopyramide Disopyramide The risk or severity of QTc prolongation can be increased when Felbamate is combined with Disopyramide.
Valproic Acid Valproic Acid The serum concentration of Valproic acid can be increased when it is combined with Felbamate.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be increased when combined with Felbamate.
Butabarbital Butabarbital The serum concentration of Felbamate can be increased when it is combined with Butabarbital.
Methimazole Methimazole The metabolism of Felbamate can be decreased when combined with Methimazole.
Chlorpropamide Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Felbamate.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Felbamate.
Tolazamide Tolazamide The metabolism of Tolazamide can be decreased when combined with Felbamate.
Dextromethorphan Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Felbamate.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Felbamate is combined with Cyclobenzaprine.
Niacin Niacin The metabolism of Felbamate can be decreased when combined with Niacin.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Felbamate.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Felbamate.
Cyproheptadine Cyproheptadine Felbamate may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine.
Clemastine Clemastine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Clemastine.
Chlorpheniramine Chlorpheniramine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Felbamate.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Meclizine is combined with Felbamate.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Felbamate is combined with Hydrochlorothiazide.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Felbamate is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone The risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Felbamate.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Felbamate.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Methocarbamol is combined with Felbamate.
Disulfiram Disulfiram The metabolism of Felbamate can be decreased when combined with Disulfiram.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Felbamate.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be increased when combined with Felbamate.
Amphotericin B Injection Amphotericin B Injection The therapeutic efficacy of Felbamate can be decreased when used in combination with Amphotericin B.
Mercaptopurine Mercaptopurine Felbamate may increase the excretion rate of Mercaptopurine which could result in a lower serum level and potentially a reduction in efficacy.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Felbamate.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Nalbuphine is combined with Felbamate.
Oxytocin Injection Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Felbamate.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Felbamate.
Flavoxate Flavoxate Felbamate may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Papaverine Papaverine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Papaverine.
Fluorouracil Injection Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Felbamate is combined with Fluorouracil.
Colchicine Colchicine The metabolism of Felbamate can be increased when combined with Colchicine.
Cephalexin Cephalexin The metabolism of Cephalexin can be increased when combined with Felbamate.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Acetazolamide is combined with Felbamate.
Cefotaxime Injection Cefotaxime Injection The therapeutic efficacy of Felbamate can be decreased when used in combination with Cefotaxime.
Ketoconazole Ketoconazole The risk or severity of QTc prolongation can be increased when Felbamate is combined with Ketoconazole.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Felbamate is combined with Pyrantel.
Thiotepa Injection Thiotepa Injection The metabolism of Thiotepa can be increased when combined with Felbamate.
Vincristine Injection Vincristine Injection The metabolism of Vincristine can be increased when combined with Felbamate.
Vinblastine Vinblastine The metabolism of Vinblastine can be increased when combined with Felbamate.
Metoprolol Metoprolol The metabolism of Metoprolol can be increased when combined with Felbamate.
Hydroxyzine Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Felbamate.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Felbamate is combined with Thiothixene.
Aspirin Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Felbamate.
Chlorambucil Chlorambucil The therapeutic efficacy of Felbamate can be decreased when used in combination with Chlorambucil.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Felbamate.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Felbamate.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Triazolam is combined with Felbamate.
Dicyclomine Dicyclomine Felbamate may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine Hyoscyamine Felbamate may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline Propantheline Felbamate may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Trimethoprim Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Felbamate.
Diltiazem Diltiazem The risk or severity of QTc prolongation can be increased when Felbamate is combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Felbamate can be decreased when combined with Nifedipine.
Timolol Timolol The metabolism of Timolol can be decreased when combined with Felbamate.
Verapamil Verapamil The metabolism of Verapamil can be decreased when combined with Felbamate.
Pindolol Pindolol The risk or severity of adverse effects can be increased when Felbamate is combined with Pindolol.
Piroxicam Piroxicam The metabolism of Piroxicam can be decreased when combined with Felbamate.
Streptozocin Streptozocin The metabolism of Felbamate can be increased when combined with Streptozocin.
Etoposide Etoposide The metabolism of Etoposide can be increased when combined with Felbamate.
Glyburide Glyburide The metabolism of Glyburide can be decreased when combined with Felbamate.
Glipizide Glipizide The metabolism of Glipizide can be decreased when combined with Felbamate.
Indapamide Indapamide The risk or severity of QTc prolongation can be increased when Indapamide is combined with Felbamate.
Pentoxifylline Pentoxifylline Felbamate may increase the excretion rate of Pentoxifylline which could result in a lower serum level and potentially a reduction in efficacy.
Pentamidine Injection Pentamidine Injection The risk or severity of QTc prolongation can be increased when Felbamate is combined with Pentamidine.
Labetalol Labetalol The metabolism of Labetalol can be decreased when combined with Felbamate.
Leuprolide Injection Leuprolide Injection The risk or severity of QTc prolongation can be increased when Felbamate is combined with Leuprolide.
Pimozide Pimozide The metabolism of Pimozide can be increased when combined with Felbamate.
Flurbiprofen Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Felbamate.
Amiodarone Amiodarone The metabolism of Amiodarone can be increased when combined with Felbamate.
Ciprofloxacin Ciprofloxacin The risk or severity of QTc prolongation can be increased when Felbamate is combined with Ciprofloxacin.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Felbamate.
Fluoxetine Fluoxetine Felbamate may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Nimodipine Nimodipine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Nimodipine.
Clozapine Clozapine Felbamate may increase the central nervous system depressant (CNS depressant) activities of Clozapine.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Felbamate is combined with Estazolam.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Felbamate.
Ofloxacin Ofloxacin The risk or severity of QTc prolongation can be increased when Felbamate is combined with Ofloxacin.
Clarithromycin Clarithromycin The risk or severity of QTc prolongation can be increased when Felbamate is combined with Clarithromycin.
Etodolac Etodolac The metabolism of Etodolac can be decreased when combined with Felbamate.
Felodipine Felodipine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Felodipine.
Nabumetone Nabumetone The metabolism of Nabumetone can be decreased when combined with Felbamate.
Teniposide Injection Teniposide Injection The metabolism of Teniposide can be increased when combined with Felbamate.
Itraconazole Itraconazole The metabolism of Felbamate can be decreased when combined with Itraconazole.
Sotalol Sotalol The risk or severity of QTc prolongation can be increased when Felbamate is combined with Sotalol.
Zolpidem Zolpidem Felbamate may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin Doxazosin The metabolism of Doxazosin can be decreased when combined with Felbamate.
Isradipine Isradipine The risk or severity of QTc prolongation can be increased when Isradipine is combined with Felbamate.
Omeprazole Omeprazole The metabolism of Omeprazole can be decreased when combined with Felbamate.
Cisapride Cisapride The risk or severity of QTc prolongation can be increased when Felbamate is combined with Cisapride.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Felbamate is combined with Gabapentin.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Felbamate.
Venlafaxine Venlafaxine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Felbamate.
Famciclovir Famciclovir The metabolism of Famciclovir can be increased when combined with Felbamate.
Fluvoxamine Fluvoxamine The risk or severity of adverse effects can be increased when Felbamate is combined with Fluvoxamine.
Nefazodone Nefazodone The risk or severity of adverse effects can be increased when Nefazodone is combined with Felbamate.
Lamotrigine Lamotrigine The risk or severity of adverse effects can be increased when Lamotrigine is combined with Felbamate.
Losartan Losartan The metabolism of Losartan can be decreased when combined with Felbamate.
Tramadol Tramadol The metabolism of Tramadol can be increased when combined with Felbamate.
Vinorelbine Injection Vinorelbine Injection The metabolism of Vinorelbine can be increased when combined with Felbamate.
Moexipril Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Felbamate.
Lansoprazole Lansoprazole The metabolism of Lansoprazole can be decreased when combined with Felbamate.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Felbamate.
Nicardipine Nicardipine Felbamate may increase the central nervous system depressant (CNS depressant) activities of Nicardipine.
Bupropion Bupropion The metabolism of Bupropion can be decreased when combined with Felbamate.
Ticlopidine Ticlopidine The metabolism of Ticlopidine can be increased when combined with Felbamate.
Saquinavir Saquinavir The risk or severity of QTc prolongation can be increased when Felbamate is combined with Saquinavir.
Riluzole Riluzole The risk or severity of adverse effects can be increased when Riluzole is combined with Felbamate.
Glimepiride Glimepiride The metabolism of Glimepiride can be decreased when combined with Felbamate.
Ritonavir Ritonavir The serum concentration of Felbamate can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Felbamate.
Clomipramine Clomipramine The metabolism of Clomipramine can be increased when combined with Felbamate.
Zafirlukast Zafirlukast The metabolism of Zafirlukast can be decreased when combined with Felbamate.
Mirtazapine Mirtazapine Felbamate may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Felbamate.
Zileuton Zileuton The metabolism of Zileuton can be decreased when combined with Felbamate.
Valsartan Valsartan The metabolism of Valsartan can be decreased when combined with Felbamate.
Pramipexole Pramipexole Felbamate may increase the sedative activities of Pramipexole.
Donepezil Donepezil The metabolism of Donepezil can be decreased when combined with Felbamate.
Nelfinavir Nelfinavir The risk or severity of QTc prolongation can be increased when Nelfinavir is combined with Felbamate.
Azithromycin Azithromycin The risk or severity of QTc prolongation can be increased when Felbamate is combined with Azithromycin.
Carvedilol Carvedilol The metabolism of Carvedilol can be decreased when combined with Felbamate.
Selegiline Selegiline The metabolism of Selegiline can be decreased when combined with Felbamate.
Bicalutamide Bicalutamide The metabolism of Bicalutamide can be increased when combined with Felbamate.
Sertraline Sertraline The risk or severity of adverse effects can be increased when Felbamate is combined with Sertraline.
Propafenone Propafenone The risk or severity of QTc prolongation can be increased when Felbamate is combined with Propafenone.
Irbesartan Irbesartan The metabolism of Irbesartan can be decreased when combined with Felbamate.
Ropinirole Ropinirole Felbamate may increase the sedative activities of Ropinirole.
Quetiapine Quetiapine The risk or severity of QTc prolongation can be increased when Felbamate is combined with Quetiapine.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Felbamate.
Paroxetine Paroxetine The risk or severity of adverse effects can be increased when Felbamate is combined with Paroxetine.
Tolcapone Tolcapone The risk or severity of adverse effects can be increased when Tolcapone is combined with Felbamate.
Citalopram Citalopram Felbamate may increase the QTc-prolonging activities of Citalopram.
Capecitabine Capecitabine The metabolism of Capecitabine can be decreased when combined with Felbamate.
Efavirenz Efavirenz The risk or severity of QTc prolongation can be increased when Felbamate is combined with Efavirenz.
Sildenafil Sildenafil The metabolism of Sildenafil can be decreased when combined with Felbamate.
Celecoxib Celecoxib The metabolism of Celecoxib can be decreased when combined with Felbamate.
Rosiglitazone Rosiglitazone The metabolism of Rosiglitazone can be decreased when combined with Felbamate.
Tolterodine Tolterodine The metabolism of Tolterodine can be decreased when combined with Felbamate.
Thalidomide Thalidomide Felbamate may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Nateglinide Nateglinide The metabolism of Nateglinide can be decreased when combined with Felbamate.
Galantamine Galantamine The risk or severity of QTc prolongation can be increased when Galantamine is combined with Felbamate.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Felbamate is combined with Levetiracetam.
Rabeprazole Rabeprazole The metabolism of Rabeprazole can be decreased when combined with Felbamate.
Terbinafine Terbinafine The metabolism of Terbinafine can be decreased when combined with Felbamate.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists