Fluoxetine

Generic name: Pronounced as (floo ox' e teen)
Brand names
  • Prozac®
  • Prozac® Weekly
  • Rapiflux®
  • Sarafem®
  • Selfemra®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 01/15/2022

A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as fluoxetine during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. However, experts are not sure about how great this risk is and how much it should be considered in deciding whether a child or teenager should take an antidepressant.

You should know that your mental health may change in unexpected ways when you take fluoxetine or other antidepressants even if you are an adult over 24 years of age. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own.

Your healthcare provider will want to see you often while you are taking fluoxetine, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor.

The doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with fluoxetine. Read the information carefully and ask your doctor or pharmacist if you have any questions. You also can obtain the Medication Guide from the FDA website: http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm.

No matter your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal. This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or mania (frenzied, abnormally excited mood) or has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and personal and family medical history. You and your doctor will decide what type of treatment is right for you.

Fluoxetine is used to treat depression, obsessive-compulsive disorder (bothersome thoughts that won't go away and the need to perform certain actions over and over), some eating disorders, and panic attacks (sudden, unexpected attacks of extreme fear and worry about these attacks). Fluoxetine is also used to relieve the symptoms of premenstrual dysphoric disorder, including mood swings, irritability, bloating, and breast tenderness. It is also used along with olanzapine (Zyprexa) to treat depression that did not respond to other medications and episodes of depression in people with bipolar I disorder (manic-depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods). Fluoxetine is in a class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.

Fluoxetine comes as a capsule, a tablet, a delayed-release (releases the medication in the intestine) capsule, and a solution (liquid) to take by mouth. Fluoxetine may be taken with or without food. Fluoxetine capsules, tablets, and liquid are usually taken once a day in the morning or twice a day in the morning and at noon. Fluoxetine delayed-released capsules are usually taken once a week. Take fluoxetine at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take fluoxetine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the delayed-release capsules whole; do not cut, crush, or chew them.

Your doctor may start you on a low dose of fluoxetine and gradually increase your dose.

It may take 4 to 5 weeks or longer before you feel the full benefit of fluoxetine. Continue to take fluoxetine even if you feel well. Do not stop taking fluoxetine without talking to your doctor. If you suddenly stop taking fluoxetine, you may experience withdrawal symptoms such as mood changes, irritability, agitation, dizziness, numbness or tingling in the hands or feet, anxiety, sweating, confusion, headache, tiredness, and difficulty falling asleep or staying asleep. Your doctor will probably decrease your dose gradually.

Fluoxetine is also sometimes used to treat alcoholism, attention-deficit disorder, borderline personality disorder, sleep disorders, headaches, mental illness, posttraumatic stress disorder, Tourette's syndrome, obesity, sexual problems, and phobias. Talk to your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking fluoxetine,

  • tell your doctor and pharmacist if you are allergic to fluoxetine, any other medications, or any of the ingredients in fluoxetine capsules, tablets, or solution. Ask your pharmacist for a list of the ingredients.

  • tell your doctor if you are taking pimozide (Orap), thioridazine, or a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline (Emsam, Zelapar), and tranylcypromine (Parnate), or if you have stopped taking a monoamine oxidase inhibitor within the past 2 weeks. Your doctor will probably tell you that you should not take fluoxetine. If you stop taking fluoxetine, you should wait at least 5 weeks before you begin to take thioridazine or a monoamine oxidase inhibitor.

  • tell your doctor and pharmacist what other prescription and nonprescription medications and vitamins you are taking or plan to take. Be sure to mention any of the following: alprazolam (Xanax); amiodarone (Pacerone, Nexterone); certain antibiotics such as erythromycin (E.E.S, Eryc, Ery-tab), gatifloxacin, moxifloxacin (Avelox), and sparfloxacin (no longer available in U.S., Zagam); amphetamines such as amphetamine (in Adderall), dextroamphetamine (Dexedrine, Dextrostat, in Adderall), and methamphetamine (Desoxyn); anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); antidepressants (mood elevators) such as amitriptyline, amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin, imipramine (Tofranil), nortriptyline (Pamelor), protriptyline, and trimipramine; aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); buspirone; clopidogrel (Plavix); diazepam (Valium, Valtoco); digoxin (Lanoxin); diuretics ('water pills'); dolasetron (Anzemet); fentanyl (Fentora, Lazanda, Subsys, others); flecainide; insulin or oral medications for diabetes; lithium (Lithobid); medications for anxiety and Parkinson's disease; medications for mental illness such as chlorpromazine, clozapine (Clozaril, Versacloz), droperidol (Inapsine), haloperidol (Haldol), iloperidone (Fanapt), and ziprasidone (Geodon); methadone (Methadose); medications for migraine headaches such as almotriptan, eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); pentamidine (Pentam); quinidine (in Nuedexta); procainamide; medications for seizures such as carbamazepine (Epitol, Equetro, Tegretol, Teril) and phenytoin (Dilantin, Phenytek); sedatives; sleeping pills; other selective serotonin-reuptake inhibitors such as citalopram (Celexa), or fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft); serotonin–norepinephrine reuptake inhibitors (SNRI) medications desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), and venlafaxine; sotalol (Betapace, Sorine); tramadol (Conzip, Qdolo, Ultram, in Ultracet); tranquilizers; and vinblastine. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor what nutritional supplements and herbal products you are taking, especially products that contain St. John's wort or tryptophan.

  • tell your doctor if you or anyone in your family has or has ever had a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death). Also tell your doctor if you have a low level of potassium, magnesium, or sodium in your blood or are being treated with electroshock therapy (procedure in which small electric shocks are administered to the brain to treat certain mental illnesses). Tell your doctor if you have recently had a heart attack and if you have or have ever had a slow or irregular heartbeat, heart failure, or any other heart problems; high blood pressure; bleeding problems; a stroke; diabetes; seizures; or liver or kidney disease.

  • tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, or if you plan to become pregnant or are breastfeeding. If you become pregnant while taking fluoxetine, call your doctor. Fluoxetine may cause problems in newborns following delivery if it is taken during the last months of pregnancy.

  • you should know that fluoxetine may make you drowsy and may affect your judgment, thinking, and movements. Do not drive a car or operate machinery until you know how this medication affects you.

  • remember that alcohol can add to the drowsiness caused by this medication.

  • you should know that fluoxetine may cause angle-closure glaucoma (a condition where the fluid is suddenly blocked and unable to flow out of the eye causing a quick, severe increase in eye pressure which may lead to a loss of vision). Talk to your doctor about having an eye examination before you start taking this medication. If you have nausea, eye pain, changes in vision, such as seeing colored rings around lights, and swelling or redness in or around the eye, call your doctor or get emergency medical treatment right away.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Fluoxetine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • nervousness

    • anxiety

    • difficulty falling asleep or staying asleep

    • nausea

    • diarrhea

    • dry mouth

    • heartburn

    • yawning

    • weakness

    • uncontrollable shaking of a part of the body

    • loss of appetite

    • weight loss

    • unusual dreams

    • stuffy nose

    • sexual problems in males; decreased sex drive, inability to get or keep an erection, or delayed or absent ejaculation

    • sexual problems in females; decreased sex drive, or delayed orgasm or unable to have an orgasm

    • excessive sweating

    • headache, confusion, weakness, difficulty concentrating, or memory problems

  • Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING or SPECIAL PRECAUTIONS section, call your doctor immediately:

    • rash

    • hives or blisters

    • itching

    • fever

    • joint pain

    • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

    • difficulty breathing or swallowing

    • agitation, fever, sweating, confusion, fast or irregular heartbeat, shivering, severe muscle stiffness or twitching, hallucinations, loss of coordination, nausea, vomiting, or diarrhea

    • fast, slow, or irregular heartbeat

    • shortness of breath

    • dizziness or fainting

    • seizures

    • abnormal bleeding or bruising

  • Fluoxetine may decrease appetite and cause weight loss in children. Your child's doctor will watch his or her growth carefully. Talk to your child's doctor if you have concerns about your child's growth or weight while he or she is taking this medication. Talk to your child's doctor about the risks of giving fluoxetine to your child.

  • Fluoxetine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat, and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

  • unsteadiness

  • confusion

  • unresponsiveness

  • nervousness

  • uncontrollable shaking of a part of the body

  • dizziness

  • rapid, irregular, or pounding heartbeat

  • seeing things or hearing voices that do not exist (hallucinating)

  • fever

  • fainting

  • seizures

  • coma (loss of consciousness for a period of time)

Keep all appointments with your doctor.

Before having any laboratory test (especially those that involve methylene blue), tell your doctor and the laboratory personnel that you are taking fluoxetine.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • Symbyax® (containing Fluoxetine, Olanzapine)

Drug Interaction
Moxifloxacin Moxifloxacin The risk or severity of QTc prolongation can be increased when Moxifloxacin is combined with Fluoxetine.
Repaglinide Repaglinide The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Repaglinide.
Montelukast Montelukast The metabolism of Montelukast can be decreased when combined with Fluoxetine.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection The metabolism of Fluoxetine can be increased when combined with Insulin glargine.
Leflunomide Leflunomide The serum concentration of Fluoxetine can be decreased when it is combined with Leflunomide.
Delavirdine Delavirdine The serum concentration of Fluoxetine can be increased when it is combined with Delavirdine.
Nevirapine Nevirapine The serum concentration of Nevirapine can be increased when it is combined with Fluoxetine.
Dolasetron Dolasetron The serum concentration of Dolasetron can be increased when it is combined with Fluoxetine.
Aminophylline Aminophylline The metabolism of Aminophylline can be decreased when combined with Fluoxetine.
Anagrelide Anagrelide The risk or severity of QTc prolongation can be increased when Anagrelide is combined with Fluoxetine.
Bisacodyl Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Fluoxetine.
Candesartan Candesartan The metabolism of Candesartan can be decreased when combined with Fluoxetine.
Cilostazol Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Fluoxetine.
Clopidogrel Clopidogrel The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Fluoxetine resulting in a loss in efficacy.
Diphenoxylate Diphenoxylate The risk or severity of serotonin syndrome can be increased when Diphenoxylate is combined with Fluoxetine.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The risk or severity of QTc prolongation can be increased when Erythromycin is combined with Fluoxetine.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The metabolism of Fluoxetine can be decreased when combined with Conjugated estrogens.
Fenofibrate Fenofibrate The metabolism of Fluoxetine can be decreased when combined with Fenofibrate.
Guanfacine Guanfacine Guanfacine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Magnesium Hydroxide Magnesium Hydroxide The therapeutic efficacy of Magnesium hydroxide can be decreased when used in combination with Fluoxetine.
Magnesium Oxide Magnesium Oxide The therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Fluoxetine.
Miglitol Miglitol The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Miglitol.
Naratriptan Naratriptan The risk or severity of serotonin syndrome can be increased when Naratriptan is combined with Fluoxetine.
Olsalazine Olsalazine The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Olsalazine.
Paregoric Paregoric The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Morphine.
Penbutolol Penbutolol The serum concentration of Acebutolol can be increased when it is combined with Fluoxetine.
Pentazocine Pentazocine The risk or severity of serotonin syndrome can be increased when Pentazocine is combined with Fluoxetine.
Polyethylene glycol-electrolyte solution (PEG-ES) Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Fluoxetine.
Psyllium Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Fluoxetine.
Ranitidine Ranitidine The metabolism of Ranitidine can be decreased when combined with Fluoxetine.
Reserpine Reserpine Reserpine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Rizatriptan Rizatriptan The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Sumatriptan is combined with Fluoxetine.
Tacrolimus Tacrolimus The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Tacrolimus.
Tizanidine Tizanidine Tizanidine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Zolmitriptan Zolmitriptan The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Fluoxetine.
Famotidine Injection Famotidine Injection The risk or severity of QTc prolongation can be increased when Famotidine is combined with Fluoxetine.
Fluconazole Injection Fluconazole Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Fluoxetine.
Foscarnet Injection Foscarnet Injection The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Foscarnet.
Hydromorphone Injection Hydromorphone Injection The risk or severity of serotonin syndrome can be increased when Hydromorphone is combined with Fluoxetine.
Interferon Beta-1b Injection Interferon Beta-1b Injection The metabolism of Fluoxetine can be decreased when combined with Interferon beta-1b.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The metabolism of Fluoxetine can be decreased when combined with Interferon gamma-1b.
Levofloxacin Injection Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Levofloxacin is combined with Fluoxetine.
Meperidine Injection Meperidine Injection The serum concentration of Meperidine can be increased when it is combined with Fluoxetine.
Metoclopramide Injection Metoclopramide Injection The risk or severity of sedation can be increased when Metoclopramide is combined with Fluoxetine.
Metronidazole Injection Metronidazole Injection The risk or severity of QTc prolongation can be increased when Metronidazole is combined with Fluoxetine.
Morphine Injection Morphine Injection The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Morphine.
Zidovudine Injection Zidovudine Injection The metabolism of Zidovudine can be decreased when combined with Fluoxetine.
Altretamine Altretamine The serum concentration of Amphetamine can be increased when it is combined with Fluoxetine.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Fluoxetine.
Ondansetron Ondansetron The serum concentration of Ondansetron can be increased when it is combined with Fluoxetine.
Enoxaparin Injection Enoxaparin Injection The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Enoxaparin.
Granisetron Granisetron The risk or severity of serotonin syndrome can be increased when Granisetron is combined with Fluoxetine.
Torsemide Torsemide The metabolism of Torasemide can be decreased when combined with Fluoxetine.
Alosetron Alosetron Alosetron may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Dofetilide Dofetilide The risk or severity of QTc prolongation can be increased when Dofetilide is combined with Fluoxetine.
Entacapone Entacapone Entacapone may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Hydroxychloroquine Hydroxychloroquine The risk or severity of QTc prolongation can be increased when Hydroxychloroquine is combined with Fluoxetine.
Meloxicam Meloxicam The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Meloxicam.
Oxcarbazepine Oxcarbazepine Oxcarbazepine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Pantoprazole Pantoprazole The metabolism of Pantoprazole can be decreased when combined with Fluoxetine.
Telmisartan Telmisartan The metabolism of Fluoxetine can be decreased when combined with Telmisartan.
Zaleplon Zaleplon Zaleplon may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Anakinra Anakinra The metabolism of Fluoxetine can be increased when combined with Anakinra.
Desloratadine Desloratadine Desloratadine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Linezolid Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Fluoxetine.
Pentosan Polysulfate Pentosan Polysulfate The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Pentosan polysulfate.
Rivastigmine Rivastigmine The therapeutic efficacy of Fluoxetine can be decreased when used in combination with Rivastigmine.
Trimipramine Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Fluoxetine.
Etanercept Injection Etanercept Injection The metabolism of Fluoxetine can be increased when combined with Etanercept.
Glycopyrrolate Glycopyrrolate Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Modafinil Modafinil The metabolism of Fluoxetine can be decreased when combined with Modafinil.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Choline magnesium trisalicylate.
Epinephrine Injection Epinephrine Injection The metabolism of Fluoxetine can be decreased when combined with Epinephrine.
Escitalopram Escitalopram The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Escitalopram.
Zonisamide Zonisamide Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Fluoxetine can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The serum concentration of Fluoxetine can be increased when it is combined with Aripiprazole.
Atomoxetine Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Fluoxetine.
Dexmethylphenidate Dexmethylphenidate The risk or severity of serotonin syndrome can be increased when Dexmethylphenidate is combined with Fluoxetine.
Teriparatide Injection Teriparatide Injection The therapeutic efficacy of Teriparatide can be decreased when used in combination with Fluoxetine.
Atazanavir Atazanavir The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Atazanavir.
Almotriptan Almotriptan The serum concentration of Almotriptan can be increased when it is combined with Fluoxetine.
Eletriptan Eletriptan The serum concentration of Eletriptan can be increased when it is combined with Fluoxetine.
Mefloquine Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Fluoxetine.
Polyethylene Glycol 3350 Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Fluoxetine.
Rosuvastatin Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Fluoxetine.
Vardenafil Vardenafil The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Vardenafil.
Alfuzosin Alfuzosin The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Alfuzosin.
Aprepitant Aprepitant The metabolism of Fluoxetine can be decreased when combined with Aprepitant.
Interferon Beta-1a Subcutaneous Injection Interferon Beta-1a Subcutaneous Injection The metabolism of Fluoxetine can be decreased when combined with Interferon beta-1a.
Memantine Memantine The metabolism of Fluoxetine can be decreased when combined with Memantine.
Tegaserod Tegaserod The serum concentration of Tegaserod can be increased when it is combined with Fluoxetine.
Frovatriptan Frovatriptan The risk or severity of serotonin syndrome can be increased when Frovatriptan is combined with Fluoxetine.
Gemifloxacin Gemifloxacin The risk or severity of QTc prolongation can be increased when Gemifloxacin is combined with Fluoxetine.
Progesterone Progesterone The serum concentration of Progesterone can be increased when it is combined with Fluoxetine.
Apomorphine Injection Apomorphine Injection The risk or severity of serotonin syndrome can be increased when Apomorphine is combined with Fluoxetine.
Infliximab Injection Infliximab Injection The metabolism of Fluoxetine can be increased when combined with Infliximab.
Oxandrolone Oxandrolone The metabolism of Fluoxetine can be decreased when combined with Oxandrolone.
Protriptyline Protriptyline The serum concentration of Fluoxetine can be increased when it is combined with Protriptyline.
Rifaximin Rifaximin The metabolism of Fluoxetine can be increased when combined with Rifaximin.
Duloxetine Duloxetine The serum concentration of Duloxetine can be increased when it is combined with Fluoxetine.
Trospium Trospium Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Bosentan Bosentan The metabolism of Bosentan can be decreased when combined with Fluoxetine.
Cinacalcet Cinacalcet The metabolism of Fluoxetine can be decreased when combined with Cinacalcet.
Erlotinib Erlotinib The serum concentration of Erlotinib can be increased when it is combined with Fluoxetine.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Fluoxetine is combined with Eszopiclone.
Insulin Aspart (rDNA Origin) Injection Insulin Aspart (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Insulin aspart.
Solifenacin Solifenacin The serum concentration of Fluoxetine can be increased when it is combined with Solifenacin.
Voriconazole Voriconazole The risk or severity of QTc prolongation can be increased when Voriconazole is combined with Fluoxetine.
Dextroamphetamine Dextroamphetamine The serum concentration of Amphetamine can be increased when it is combined with Fluoxetine.
Entecavir Entecavir The metabolism of Fluoxetine can be decreased when combined with Entecavir.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The metabolism of Fluoxetine can be decreased when combined with Peginterferon alfa-2a.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The serum concentration of Fluoxetine can be decreased when it is combined with Peginterferon alfa-2b.
Pramlintide Injection Pramlintide Injection The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Pramlintide.
Sodium Oxybate Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Exenatide Injection Exenatide Injection The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Exenatide.
Ibandronate Ibandronate The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Ibandronate.
Isocarboxazid Isocarboxazid The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Isocarboxazid.
Ramelteon Ramelteon Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Ramelteon.
Darifenacin Darifenacin The serum concentration of Darifenacin can be increased when it is combined with Fluoxetine.
Fentanyl Fentanyl The risk or severity of serotonin syndrome can be increased when Fentanyl is combined with Fluoxetine.
Pregabalin Pregabalin The therapeutic efficacy of Fluoxetine can be increased when used in combination with Pregabalin.
Deferasirox Deferasirox The serum concentration of Fluoxetine can be increased when it is combined with Deferasirox.
Phenylephrine Phenylephrine The metabolism of Fluoxetine can be increased when combined with Phenylephrine.
Tipranavir Tipranavir The serum concentration of Tipranavir can be increased when it is combined with Fluoxetine.
Felbamate Felbamate Felbamate may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Insulin Detemir (rDNA Origin) Injection Insulin Detemir (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Insulin detemir.
Ranolazine Ranolazine The serum concentration of Ranolazine can be increased when it is combined with Fluoxetine.
Abatacept Injection Abatacept Injection The metabolism of Fluoxetine can be increased when combined with Abatacept.
Rasagiline Rasagiline The risk or severity of serotonin syndrome can be increased when Rasagiline is combined with Fluoxetine.
Imatinib Imatinib The serum concentration of Imatinib can be increased when it is combined with Fluoxetine.
Sitagliptin Sitagliptin The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Sitagliptin.
Gefitinib Gefitinib The serum concentration of Gefitinib can be increased when it is combined with Fluoxetine.
Albuterol Albuterol The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Salbutamol.
Paliperidone Paliperidone The serum concentration of Paliperidone can be increased when it is combined with Fluoxetine.
Bortezomib Bortezomib The serum concentration of Bortezomib can be increased when it is combined with Fluoxetine.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection The metabolism of Fluoxetine can be increased when combined with Insulin glulisine.
Lubiprostone Lubiprostone The therapeutic efficacy of Lubiprostone can be decreased when used in combination with Fluoxetine.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Oxaliplatin is combined with Fluoxetine.
Posaconazole Posaconazole The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Posaconazole.
Primaquine Primaquine The risk or severity of QTc prolongation can be increased when Primaquine is combined with Fluoxetine.
Pemetrexed Injection Pemetrexed Injection The metabolism of Pemetrexed can be decreased when combined with Fluoxetine.
Dimenhydrinate Dimenhydrinate Dimenhydrinate may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Lisdexamfetamine Lisdexamfetamine The serum concentration of Lisdexamfetamine can be increased when it is combined with Fluoxetine.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Vorinostat Vorinostat The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Vorinostat.
Sorafenib Sorafenib The risk or severity of QTc prolongation can be increased when Sorafenib is combined with Fluoxetine.
Sunitinib Sunitinib The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Sunitinib.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Lapatinib Lapatinib The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Lapatinib.
Levocetirizine Levocetirizine Levocetirizine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Dasatinib Dasatinib The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Dasatinib.
Mexiletine Mexiletine The serum concentration of Mexiletine can be increased when it is combined with Fluoxetine.
Armodafinil Armodafinil The metabolism of Fluoxetine can be decreased when combined with Armodafinil.
Paclitaxel (with polyoxyethylated castor oil) Injection Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Fluoxetine.
Temsirolimus Temsirolimus The metabolism of Fluoxetine can be decreased when combined with Temsirolimus.
Nilotinib Nilotinib The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Nilotinib.
Toremifene Toremifene The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Toremifene.
Bexarotene Bexarotene The metabolism of Bexarotene can be decreased when combined with Fluoxetine.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Fluoxetine can be decreased when combined with Chloramphenicol.
Desmopressin Desmopressin The risk or severity of hyponatremia can be increased when Fluoxetine is combined with Desmopressin.
Betaine Betaine The therapeutic efficacy of Fluoxetine can be decreased when used in combination with Glycine betaine.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Fluoxetine is combined with Botulinum toxin type A.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Botulinum Toxin Type B.
Etravirine Etravirine The metabolism of Etravirine can be decreased when combined with Fluoxetine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Arsenic trioxide.
Desvenlafaxine Desvenlafaxine The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Desvenlafaxine.
Cevimeline Cevimeline The serum concentration of Cevimeline can be increased when it is combined with Fluoxetine.
Nebivolol Nebivolol The serum concentration of Nebivolol can be increased when it is combined with Fluoxetine.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Fluoxetine.
Bendamustine Injection Bendamustine Injection The metabolism of Bendamustine can be decreased when combined with Fluoxetine.
Flecainide Flecainide The serum concentration of Flecainide can be increased when it is combined with Fluoxetine.
Certolizumab Injection Certolizumab Injection The metabolism of Fluoxetine can be increased when combined with Certolizumab pegol.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Fluoxetine.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Fluoxetine.
Rufinamide Rufinamide Rufinamide may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Midazolam Midazolam The serum concentration of Fluoxetine can be increased when it is combined with Midazolam.
Naltrexone Injection Naltrexone Injection The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Naltrexone.
Eltrombopag Eltrombopag The metabolism of Eltrombopag can be decreased when combined with Fluoxetine.
Milnacipran Milnacipran The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Milnacipran.
Dexlansoprazole Dexlansoprazole The metabolism of Dexlansoprazole can be decreased when combined with Fluoxetine.
Sodium Phosphate Sodium Phosphate The therapeutic efficacy of Sodium phosphate, monobasic can be decreased when used in combination with Fluoxetine.
Fesoterodine Fesoterodine The serum concentration of Fesoterodine can be increased when it is combined with Fluoxetine.
Degarelix Injection Degarelix Injection The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Degarelix.
Betaxolol Betaxolol The serum concentration of Betaxolol can be increased when it is combined with Fluoxetine.
Iloperidone Iloperidone The serum concentration of Fluoxetine can be increased when it is combined with Iloperidone.
Prasugrel Prasugrel The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Prasugrel.
Lacosamide Lacosamide Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Lacosamide.
Everolimus Everolimus The metabolism of Fluoxetine can be decreased when combined with Everolimus.
Dronedarone Dronedarone Fluoxetine may increase the QTc-prolonging activities of Dronedarone.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Fluoxetine is combined with Botulinum toxin type A.
Palonosetron Injection Palonosetron Injection The serum concentration of Palonosetron can be increased when it is combined with Fluoxetine.
Saxagliptin Saxagliptin The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Saxagliptin.
Telavancin Injection Telavancin Injection The risk or severity of QTc prolongation can be increased when Telavancin is combined with Fluoxetine.
Romidepsin Injection Romidepsin Injection The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Romidepsin.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Golimumab Injection Golimumab Injection The metabolism of Fluoxetine can be increased when combined with Golimumab.
Pazopanib Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Fluoxetine.
Asenapine Asenapine The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Asenapine.
Vigabatrin Vigabatrin Vigabatrin may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Fluoxetine.
Albendazole Albendazole The metabolism of Albendazole can be decreased when combined with Fluoxetine.
Oxymorphone Oxymorphone The serum concentration of Oxymorphone can be increased when it is combined with Fluoxetine.
Dabigatran Dabigatran The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Dabigatran.
Liraglutide Injection Liraglutide Injection The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Liraglutide.
Tocilizumab Injection Tocilizumab Injection The metabolism of Fluoxetine can be increased when combined with Tocilizumab.
Dalfampridine Dalfampridine The risk or severity of seizure can be increased when Fluoxetine is combined with Dalfampridine.
Fingolimod Fingolimod The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Fingolimod.
Eribulin Injection Eribulin Injection The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Eribulin.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Fluoxetine is combined with Botulinum toxin type A.
Lurasidone Lurasidone The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Lurasidone.
Acetaminophen Injection Acetaminophen Injection The serum concentration of Acetaminophen can be increased when it is combined with Fluoxetine.
Vilazodone Vilazodone The serum concentration of Vilazodone can be increased when it is combined with Fluoxetine.
Terbutaline Injection Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Fluoxetine.
Linagliptin Linagliptin The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Linagliptin.
Rilpivirine Rilpivirine The risk or severity of QTc prolongation can be increased when Rilpivirine is combined with Fluoxetine.
Potassium Iodide Potassium Iodide The therapeutic efficacy of Potassium Iodide can be decreased when used in combination with Fluoxetine.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Fluoxetine.
Abiraterone Abiraterone The serum concentration of Fluoxetine can be increased when it is combined with Abiraterone.
Triptorelin Injection Triptorelin Injection The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Triptorelin.
Rivaroxaban Rivaroxaban The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Rivaroxaban.
Ticagrelor Ticagrelor The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Ticagrelor.
Vandetanib Vandetanib The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Vandetanib.
Clobazam Clobazam The serum concentration of Fluoxetine can be increased when it is combined with Clobazam.
Vemurafenib Vemurafenib The serum concentration of Fluoxetine can be increased when it is combined with Vemurafenib.
Vismodegib Vismodegib The metabolism of Vismodegib can be decreased when combined with Fluoxetine.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Fluoxetine.
Crizotinib Crizotinib The risk or severity of QTc prolongation can be increased when Crizotinib is combined with Fluoxetine.
Cabergoline Cabergoline The risk or severity of serotonin syndrome can be increased when Cabergoline is combined with Fluoxetine.
Fondaparinux Injection Fondaparinux Injection The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Fondaparinux.
Ezogabine Ezogabine Tiagabine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Iloprost Iloprost The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Iloprost.
Enzalutamide Enzalutamide The metabolism of Enzalutamide can be increased when combined with Fluoxetine.
Mirabegron Mirabegron The serum concentration of Mirabegron can be increased when it is combined with Fluoxetine.
Regorafenib Regorafenib The metabolism of Fluoxetine can be decreased when combined with Regorafenib.
Linaclotide Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Fluoxetine.
Teriflunomide Teriflunomide The serum concentration of Fluoxetine can be decreased when it is combined with Teriflunomide.
Lorcaserin Lorcaserin The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Mecasermin.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Fluoxetine.
Bedaquiline Bedaquiline The risk or severity of QTc prolongation can be increased when Bedaquiline is combined with Fluoxetine.
Icosapent Ethyl Icosapent Ethyl The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Icosapent ethyl.
Alogliptin Alogliptin The serum concentration of Alogliptin can be increased when it is combined with Fluoxetine.
Ponatinib Ponatinib The serum concentration of Ponatinib can be increased when it is combined with Fluoxetine.
Pomalidomide Pomalidomide Pomalidomide may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Apixaban Apixaban The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Apixaban.
Canagliflozin Canagliflozin The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Canagliflozin.
Dabrafenib Dabrafenib The serum concentration of Fluoxetine can be decreased when it is combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Fluoxetine.
Levomilnacipran Levomilnacipran The serum concentration of Levomilnacipran can be increased when it is combined with Fluoxetine.
Vortioxetine Vortioxetine The serum concentration of Vortioxetine can be increased when it is combined with Fluoxetine.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Ibrutinib Ibrutinib The serum concentration of Ibrutinib can be increased when it is combined with Fluoxetine.
Ketorolac Injection Ketorolac Injection The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Ketorolac.
Simeprevir Simeprevir The metabolism of Fluoxetine can be decreased when combined with Simeprevir.
Dapagliflozin Dapagliflozin The serum concentration of Dapagliflozin can be increased when it is combined with Fluoxetine.
Apremilast Apremilast The metabolism of Fluoxetine can be increased when combined with Apremilast.
Ceritinib Ceritinib The risk or severity of QTc prolongation can be increased when Ceritinib is combined with Fluoxetine.
Siltuximab Injection Siltuximab Injection The metabolism of Fluoxetine can be increased when combined with Siltuximab.
Albiglutide Injection Albiglutide Injection The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Albiglutide.
Eslicarbazepine Eslicarbazepine Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Belinostat Injection Belinostat Injection The metabolism of Fluoxetine can be increased when combined with Belinostat.
Testosterone Injection Testosterone Injection The metabolism of Testosterone can be decreased when combined with Fluoxetine.
Oritavancin Injection Oritavancin Injection The metabolism of Fluoxetine can be decreased when combined with Oritavancin.
Empagliflozin Empagliflozin The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Empagliflozin.
Vorapaxar Vorapaxar The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Vorapaxar.
Hydrocodone Hydrocodone Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Suvorexant Suvorexant Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Dulaglutide Injection Dulaglutide Injection The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Dulaglutide.
Edoxaban Edoxaban The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Edoxaban.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The metabolism of Fluoxetine can be decreased when combined with Peginterferon beta-1a.
Olaparib Olaparib The metabolism of Olaparib can be increased when combined with Fluoxetine.
Methamphetamine Methamphetamine The serum concentration of Metamfetamine can be increased when it is combined with Fluoxetine.
Tasimelteon Tasimelteon Tasimelteon may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Lanreotide Injection Lanreotide Injection The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Lanreotide.
Pirfenidone Pirfenidone The metabolism of Fluoxetine can be decreased when combined with Pirfenidone.
Secukinumab Injection Secukinumab Injection The metabolism of Fluoxetine can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The serum concentration of Risperidone can be increased when it is combined with Fluoxetine.
Insulin Human Inhalation Insulin Human Inhalation The metabolism of Fluoxetine can be increased when combined with Insulin human.
Lenvatinib Lenvatinib The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Fluoxetine.
Naloxegol Naloxegol The metabolism of Fluoxetine can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The risk or severity of QTc prolongation can be increased when Panobinostat is combined with Fluoxetine.
Haloperidol Injection Haloperidol Injection The metabolism of Haloperidol can be decreased when combined with Fluoxetine.
Ivabradine Ivabradine The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Ivabradine.
Flibanserin Flibanserin The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Flibanserin.
Rolapitant Rolapitant The metabolism of Fluoxetine can be decreased when combined with Rolapitant.
Brexpiprazole Brexpiprazole The serum concentration of Brexpiprazole can be increased when it is combined with Fluoxetine.
Ziprasidone Injection Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Ziprasidone is combined with Fluoxetine.
Cariprazine Cariprazine The serum concentration of Cariprazine can be increased when it is combined with Fluoxetine.
Eluxadoline Eluxadoline The risk or severity of constipation can be increased when Fluoxetine is combined with Eluxadoline.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection The metabolism of Fluoxetine can be increased when combined with Insulin degludec.
Trabectedin Injection Trabectedin Injection The serum concentration of Trabectedin can be increased when it is combined with Fluoxetine.
Osimertinib Osimertinib The serum concentration of Fluoxetine can be decreased when it is combined with Osimertinib.
Rifapentine Rifapentine The metabolism of Fluoxetine can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Lesinurad can be decreased when combined with Fluoxetine.
Dexamethasone Injection Dexamethasone Injection The metabolism of Fluoxetine can be increased when combined with Dexamethasone.
Defibrotide Injection Defibrotide Injection The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Defibrotide.
Brivaracetam Injection Brivaracetam Injection Brivaracetam may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Cobicistat Cobicistat The metabolism of Fluoxetine can be decreased when combined with Cobicistat.
Pimavanserin Pimavanserin The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Pimavanserin.
Obeticholic Acid Obeticholic Acid The metabolism of Fluoxetine can be decreased when combined with Obeticholic acid.
Diphenhydramine Injection Diphenhydramine Injection The serum concentration of Diphenhydramine can be increased when it is combined with Fluoxetine.
Rucaparib Rucaparib The serum concentration of Rucaparib can be increased when it is combined with Fluoxetine.
Lixisenatide Injection Lixisenatide Injection The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Lixisenatide.
Ribociclib Ribociclib The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Ribociclib.
Parathyroid Hormone Injection Parathyroid Hormone Injection The therapeutic efficacy of Parathyroid hormone can be decreased when used in combination with Fluoxetine.
Doxepin (Insomnia) Doxepin (Insomnia) The serum concentration of Doxepin can be increased when it is combined with Fluoxetine.
Plecanatide Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Fluoxetine.
Deutetrabenazine Deutetrabenazine The serum concentration of the active metabolites of Deutetrabenazine can be increased when Deutetrabenazine is used in combination with Fluoxetine.
Valbenazine Valbenazine The serum concentration of Valbenazine can be increased when it is combined with Fluoxetine.
Safinamide Safinamide The risk or severity of serotonin syndrome can be increased when Safinamide is combined with Fluoxetine.
Midostaurin Midostaurin The metabolism of Fluoxetine can be decreased when combined with Midostaurin.
Abaloparatide Injection Abaloparatide Injection The therapeutic efficacy of Abaloparatide can be decreased when used in combination with Fluoxetine.
Enasidenib Enasidenib The serum concentration of Enasidenib can be increased when it is combined with Fluoxetine.
Delafloxacin Delafloxacin The risk or severity of QTc prolongation can be increased when Delafloxacin is combined with Fluoxetine.
Betrixaban Betrixaban The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Betrixaban.
Letermovir Letermovir The serum concentration of Letermovir can be increased when it is combined with Fluoxetine.
Semaglutide Injection Semaglutide Injection The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Semaglutide.
Tetrabenazine Tetrabenazine The serum concentration of Tetrabenazine can be increased when it is combined with Fluoxetine.
Ertugliflozin Ertugliflozin The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Ertugliflozin.
Buprenorphine Injection Buprenorphine Injection Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Apalutamide Apalutamide The serum concentration of Fluoxetine can be increased when it is combined with Apalutamide.
Avatrombopag Avatrombopag The metabolism of Fluoxetine can be increased when combined with Avatrombopag.
Lofexidine Lofexidine The therapeutic efficacy of Fluoxetine can be increased when used in combination with Lofexidine.
Eliglustat Eliglustat The serum concentration of Eliglustat can be increased when it is combined with Fluoxetine.
Encorafenib Encorafenib The serum concentration of Encorafenib can be increased when it is combined with Fluoxetine.
Binimetinib Binimetinib The metabolism of Binimetinib can be decreased when combined with Fluoxetine.
Ivosidenib Ivosidenib The risk or severity of QTc prolongation can be increased when Ivosidenib is combined with Fluoxetine.
Elagolix Elagolix The serum concentration of Elagolix can be increased when it is combined with Fluoxetine.
Tafenoquine Tafenoquine The serum concentration of Tafenoquine can be increased when it is combined with Fluoxetine.
Cannabidiol Cannabidiol The risk or severity of serotonin syndrome can be increased when Cannabidiol is combined with Fluoxetine.
Dacomitinib Dacomitinib The serum concentration of Dacomitinib can be increased when it is combined with Fluoxetine.
Stiripentol Stiripentol Stiripentol may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Gilteritinib Gilteritinib The therapeutic efficacy of Fluoxetine can be decreased when used in combination with Gilteritinib.
Glasdegib Glasdegib The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Glasdegib.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Fluoxetine.
Rifamycin Rifamycin The metabolism of Rifamycin can be increased when combined with Fluoxetine.
Prucalopride Prucalopride The therapeutic efficacy of Prucalopride can be decreased when used in combination with Fluoxetine.
Magnesium Citrate Magnesium Citrate The therapeutic efficacy of Magnesium citrate can be decreased when used in combination with Fluoxetine.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Fluoxetine can be increased when combined with Emapalumab.
Siponimod Siponimod The risk or severity of adverse effects can be increased when Fluoxetine is combined with Siponimod.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Acyclovir can be decreased when combined with Fluoxetine.
Caplacizumab-yhdp Injection Caplacizumab-yhdp Injection The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Caplacizumab.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Fluoxetine.
Esomeprazole Injection Esomeprazole Injection The metabolism of Esomeprazole can be decreased when combined with Fluoxetine.
Alpelisib Alpelisib The serum concentration of Fluoxetine can be decreased when it is combined with Alpelisib.
Brexanolone Injection Brexanolone Injection Brexanolone may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Solriamfetol Solriamfetol Solriamfetol may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Triclabendazole Triclabendazole The metabolism of Fluoxetine can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Entrectinib.
Istradefylline Istradefylline The serum concentration of Istradefylline can be increased when it is combined with Fluoxetine.
Pitolisant Pitolisant The serum concentration of Pitolisant can be increased when it is combined with Fluoxetine.
Fedratinib Fedratinib The metabolism of Fedratinib can be decreased when combined with Fluoxetine.
Lefamulin Lefamulin Fluoxetine may increase the QTc-prolonging activities of Lefamulin.
Phenytoin Injection Phenytoin Injection The risk or severity of Anticonvulsant Toxicity can be increased when Fluoxetine is combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The risk or severity of Anticonvulsant Toxicity can be increased when Fluoxetine is combined with Fosphenytoin.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Fluoxetine.
Voxelotor Voxelotor The metabolism of Voxelotor can be decreased when combined with Fluoxetine.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Fluoxetine.
Lumateperone Lumateperone Lumateperone may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Lasmiditan Lasmiditan The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Fluoxetine.
Cenobamate Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Fluoxetine.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Fluoxetine.
Selpercatinib Selpercatinib The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Selpercatinib.
Capmatinib Capmatinib The metabolism of Fluoxetine can be decreased when combined with Capmatinib.
Lemborexant Lemborexant The serum concentration of Fluoxetine can be decreased when it is combined with Lemborexant.
Fenfluramine Fenfluramine The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Fenfluramine.
Octreotide Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Fluoxetine.
Pralsetinib Pralsetinib The metabolism of Fluoxetine can be decreased when combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Fluoxetine can be decreased when it is combined with Satralizumab.
Viloxazine Viloxazine Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Viloxazine.
Theophylline Theophylline The serum concentration of Theophylline can be increased when it is combined with Fluoxetine.
Fenoprofen Fenoprofen The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Fenoprofen.
Indomethacin Indomethacin The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Indomethacin.
Mefenamic Acid Mefenamic Acid The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Mefenamic acid.
Naproxen Naproxen The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Naproxen.
Tolmetin Tolmetin The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Tolmetin.
Sulindac Sulindac The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Sulindac.
Trazodone Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Fluoxetine.
Hydroxyurea Hydroxyurea The metabolism of Fluoxetine can be decreased when combined with Hydroxyurea.
Floxuridine Floxuridine The metabolism of Fluoxetine can be decreased when combined with Floxuridine.
Phenobarbital Phenobarbital Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Phenobarbital.
Metaxalone Metaxalone The risk or severity of serotonin syndrome can be increased when Metaxalone is combined with Fluoxetine.
Levorphanol Levorphanol The risk or severity of serotonin syndrome can be increased when Levorphanol is combined with Fluoxetine.
Primidone Primidone Primidone may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Methsuximide Methsuximide Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Methsuximide.
Diethylpropion Diethylpropion The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Diethylpropion.
Chlorpromazine Chlorpromazine The serum concentration of Chlorpromazine can be increased when it is combined with Fluoxetine.
Diazepam Diazepam The serum concentration of Diazepam can be increased when it is combined with Fluoxetine.
Oxazepam Oxazepam The serum concentration of Oxazepam can be increased when it is combined with Fluoxetine.
Flurazepam Flurazepam The serum concentration of Flurazepam can be increased when it is combined with Fluoxetine.
Clorazepate Clorazepate The serum concentration of Clorazepic acid can be increased when it is combined with Fluoxetine.
Lorazepam Lorazepam The serum concentration of Fluoxetine can be increased when it is combined with Lorazepam.
Carmustine Carmustine The metabolism of Fluoxetine can be decreased when combined with Carmustine.
Amantadine Amantadine The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Amantadine.
Codeine Codeine The serum concentration of Codeine can be increased when it is combined with Fluoxetine.
Meprobamate Meprobamate Meprobamate may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Chlordiazepoxide Chlordiazepoxide The serum concentration of Chlordiazepoxide can be increased when it is combined with Fluoxetine.
Bromocriptine Bromocriptine Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Bromocriptine.
Tranylcypromine Tranylcypromine The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Tranylcypromine.
Phenelzine Phenelzine The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Phenelzine.
Procarbazine Procarbazine The risk or severity of serotonin syndrome can be increased when Procarbazine is combined with Fluoxetine.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of serotonin syndrome can be increased when Ergoloid mesylate is combined with Fluoxetine.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Prochlorperazine Prochlorperazine The serum concentration of Fluoxetine can be increased when it is combined with Prochlorperazine.
Thioridazine Thioridazine The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Thioridazine.
Trifluoperazine Trifluoperazine Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Trifluoperazine.
Dapsone Dapsone The metabolism of Fluoxetine can be decreased when combined with Dapsone.
Sulfadiazine Sulfadiazine The metabolism of Fluoxetine can be decreased when combined with Sulfadiazine.
Oxycodone Oxycodone The serum concentration of Oxycodone can be increased when it is combined with Fluoxetine.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Fluoxetine.
Oxybutynin Oxybutynin The metabolism of Oxybutynin can be decreased when combined with Fluoxetine.
Benztropine Benztropine The serum concentration of Benzatropine can be increased when it is combined with Fluoxetine.
Maprotiline Maprotiline The serum concentration of Maprotiline can be increased when it is combined with Fluoxetine.
Ibuprofen Ibuprofen The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Ibuprofen.
Trihexyphenidyl Trihexyphenidyl Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine Orphenadrine Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The serum concentration of Perphenazine can be increased when it is combined with Fluoxetine.
Azathioprine Azathioprine The metabolism of Azathioprine can be decreased when combined with Fluoxetine.
Fluphenazine Fluphenazine Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Fluphenazine.
Phentermine Phentermine The risk or severity of serotonin syndrome can be increased when Phentermine is combined with Fluoxetine.
Amoxapine Amoxapine The serum concentration of Amoxapine can be increased when it is combined with Fluoxetine.
Sulfasalazine Sulfasalazine The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Sulfasalazine.
Hydrocortisone Hydrocortisone The metabolism of Hydrocortisone can be increased when combined with Fluoxetine.
Doxorubicin Doxorubicin The metabolism of Fluoxetine can be decreased when combined with Doxorubicin.
Mechlorethamine Mechlorethamine The therapeutic efficacy of Fluoxetine can be decreased when used in combination with Mechlorethamine.
Pyridostigmine Pyridostigmine The therapeutic efficacy of Fluoxetine can be decreased when used in combination with Pyridostigmine.
Carbamazepine Carbamazepine The serum concentration of Carbamazepine can be increased when it is combined with Fluoxetine.
Molindone Molindone Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Molindone.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Fluoxetine.
Cimetidine Cimetidine The metabolism of Cimetidine can be decreased when combined with Fluoxetine.
Warfarin Warfarin The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Warfarin.
Clonazepam Clonazepam The serum concentration of Fluoxetine can be increased when it is combined with Clonazepam.
Loperamide Loperamide The serum concentration of Fluoxetine can be increased when it is combined with Loperamide.
Promethazine Promethazine The serum concentration of Promethazine can be increased when it is combined with Fluoxetine.
Meclofenamate Meclofenamate The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Meclofenamic acid.
Griseofulvin Griseofulvin The metabolism of Fluoxetine can be increased when combined with Griseofulvin.
Digoxin Digoxin The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Digoxin.
Loxapine Loxapine The risk or severity of serotonin syndrome can be increased when Loxapine is combined with Fluoxetine.
Chloroquine Chloroquine The serum concentration of Chloroquine can be increased when it is combined with Fluoxetine.
Quinine Quinine The serum concentration of Quinine can be increased when it is combined with Fluoxetine.
Ethosuximide Ethosuximide Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Ethosuximide.
Triamterene Triamterene The metabolism of Fluoxetine can be decreased when combined with Triamterene.
Lactulose Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Fluoxetine.
Sulfinpyrazone Sulfinpyrazone The metabolism of Sulfinpyrazone can be decreased when combined with Fluoxetine.
Chlorothiazide Chlorothiazide The risk or severity of hyponatremia can be increased when Fluoxetine is combined with Chlorothiazide.
Chlorthalidone Chlorthalidone The risk or severity of hyponatremia can be increased when Fluoxetine is combined with Chlorthalidone.
Metolazone Metolazone The risk or severity of hyponatremia can be increased when Fluoxetine is combined with Metolazone.
Secobarbital Secobarbital Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Desipramine Desipramine The serum concentration of Desipramine can be increased when it is combined with Fluoxetine.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Fluoxetine.
Imipramine Imipramine The serum concentration of Fluoxetine can be increased when it is combined with Imipramine.
Probenecid Probenecid The metabolism of Fluoxetine can be decreased when combined with Probenecid.
Quinidine Quinidine The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Quinidine.
Procainamide Procainamide The serum concentration of Procainamide can be increased when it is combined with Fluoxetine.
Isoniazid Isoniazid The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Fluoxetine.
Rifampin Rifampin The metabolism of Fluoxetine can be increased when combined with Rifampicin.
Disopyramide Disopyramide The risk or severity of QTc prolongation can be increased when Disopyramide is combined with Fluoxetine.
Valproic Acid Valproic Acid The risk or severity of serotonin syndrome can be increased when Valproic acid is combined with Fluoxetine.
Tamoxifen Tamoxifen The serum concentration of Tamoxifen can be increased when it is combined with Fluoxetine.
Butabarbital Butabarbital Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Levothyroxine Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Fluoxetine.
Liothyronine Liothyronine The therapeutic efficacy of Liothyronine can be decreased when used in combination with Fluoxetine.
Methimazole Methimazole The metabolism of Fluoxetine can be decreased when combined with Methimazole.
Propylthiouracil Propylthiouracil The therapeutic efficacy of Propylthiouracil can be decreased when used in combination with Fluoxetine.
Chlorpropamide Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Fluoxetine.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Fluoxetine.
Tolazamide Tolazamide The metabolism of Tolazamide can be decreased when combined with Fluoxetine.
Dextromethorphan Dextromethorphan The serum concentration of Dextromethorphan can be increased when it is combined with Fluoxetine.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Fluoxetine is combined with Cyclobenzaprine.
Niacin Niacin The metabolism of Fluoxetine can be decreased when combined with Niacin.
Baclofen Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Cyproheptadine Cyproheptadine Cyproheptadine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Clemastine Clemastine Clemastine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Chlorpheniramine Chlorpheniramine The serum concentration of Chlorpheniramine can be increased when it is combined with Fluoxetine.
Brompheniramine Brompheniramine Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Meclizine Meclizine The serum concentration of Meclizine can be increased when it is combined with Fluoxetine.
Methyclothiazide Methyclothiazide The risk or severity of hyponatremia can be increased when Fluoxetine is combined with Methyclothiazide.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Hydrochlorothiazide.
Dantrolene Dantrolene Dantrolene may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Chlorzoxazone Chlorzoxazone The serum concentration of Chlorzoxazone can be increased when it is combined with Fluoxetine.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Fluoxetine.
Methocarbamol Methocarbamol Methocarbamol may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Disulfiram Disulfiram The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Disulfiram.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Fluoxetine.
Pseudoephedrine Pseudoephedrine The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Pseudoephedrine.
Nortriptyline Nortriptyline The serum concentration of Nortriptyline can be increased when it is combined with Fluoxetine.
Nadolol Nadolol The serum concentration of Nadolol can be increased when it is combined with Fluoxetine.
Butorphanol Injection Butorphanol Injection The risk or severity of serotonin syndrome can be increased when Butorphanol is combined with Fluoxetine.
Nalbuphine Injection Nalbuphine Injection The risk or severity of serotonin syndrome can be increased when Nalbuphine is combined with Fluoxetine.
Oxytocin Injection Oxytocin Injection The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Oxytocin.
Trimethobenzamide Trimethobenzamide Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Flavoxate Flavoxate Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Papaverine Papaverine The risk or severity of QTc prolongation can be increased when Papaverine is combined with Fluoxetine.
Fluorouracil Injection Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Fluorouracil is combined with Fluoxetine.
Dacarbazine Dacarbazine The metabolism of Dacarbazine can be decreased when combined with Fluoxetine.
Acetazolamide Acetazolamide Acetazolamide may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Calcitonin Salmon Injection Calcitonin Salmon Injection The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Fluoxetine.
Ketoconazole Ketoconazole The risk or severity of QTc prolongation can be increased when Ketoconazole is combined with Fluoxetine.
Pyrantel Pyrantel Pyrantel may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Thiotepa Injection Thiotepa Injection The metabolism of Fluoxetine can be decreased when combined with Thiotepa.
Dipyridamole Dipyridamole The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Dipyridamole.
Vinblastine Vinblastine The metabolism of Fluoxetine can be decreased when combined with Vinblastine.
Metoprolol Metoprolol The serum concentration of Metoprolol can be increased when it is combined with Fluoxetine.
Hydroxyzine Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Fluoxetine.
Thiothixene Thiothixene Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Thiothixene.
Aspirin Aspirin The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Acetylsalicylic acid.
Salsalate Salsalate The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Salsalate.
Alprazolam Alprazolam The serum concentration of Fluoxetine can be increased when it is combined with Alprazolam.
Temazepam Temazepam The serum concentration of Fluoxetine can be increased when it is combined with Temazepam.
Triazolam Triazolam The serum concentration of Triazolam can be increased when it is combined with Fluoxetine.
Dicyclomine Dicyclomine Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine Hyoscyamine The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Hyoscyamine.
Propantheline Propantheline Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Trimethoprim Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Fluoxetine.
Diltiazem Diltiazem The serum concentration of Diltiazem can be increased when it is combined with Fluoxetine.
Nifedipine Nifedipine The serum concentration of Fluoxetine can be increased when it is combined with Nifedipine.
Timolol Timolol The metabolism of Timolol can be decreased when combined with Fluoxetine.
Verapamil Verapamil The metabolism of Verapamil can be decreased when combined with Fluoxetine.
Atenolol Atenolol The serum concentration of Atenolol can be increased when it is combined with Fluoxetine.
Pindolol Pindolol The serum concentration of Pindolol can be increased when it is combined with Fluoxetine.
Cisplatin Injection Cisplatin Injection The metabolism of Fluoxetine can be decreased when combined with Cisplatin.
Diflunisal Diflunisal The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Diflunisal.
Piroxicam Piroxicam The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Piroxicam.
Streptozocin Streptozocin The metabolism of Fluoxetine can be increased when combined with Streptozocin.
Etoposide Etoposide The metabolism of Etoposide can be decreased when combined with Fluoxetine.
Glyburide Glyburide The metabolism of Glyburide can be decreased when combined with Fluoxetine.
Glipizide Glipizide The metabolism of Glipizide can be decreased when combined with Fluoxetine.
Indapamide Indapamide The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Indapamide.
Nafcillin Injection Nafcillin Injection The metabolism of Fluoxetine can be increased when combined with Nafcillin.
Pentoxifylline Pentoxifylline The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Pentoxifylline.
Pentamidine Injection Pentamidine Injection The serum concentration of Pentamidine can be increased when it is combined with Fluoxetine.
Labetalol Labetalol The serum concentration of Labetalol can be increased when it is combined with Fluoxetine.
Leuprolide Injection Leuprolide Injection The risk or severity of QTc prolongation can be increased when Leuprolide is combined with Fluoxetine.
Gemfibrozil Gemfibrozil The metabolism of Fluoxetine can be decreased when combined with Gemfibrozil.
Guanabenz Guanabenz The metabolism of Guanabenz can be decreased when combined with Fluoxetine.
Ketoprofen Ketoprofen The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Ketoprofen.
Pimozide Pimozide Fluoxetine may increase the QTc-prolonging activities of Pimozide.
Flurbiprofen Flurbiprofen The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Flurbiprofen.
Amiodarone Amiodarone The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Fluoxetine.
Buspirone Buspirone The serum concentration of Buspirone can be increased when it is combined with Fluoxetine.
Lovastatin Lovastatin The metabolism of Fluoxetine can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The risk or severity of QTc prolongation can be increased when Ciprofloxacin is combined with Fluoxetine.
Mesalamine Mesalamine The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Mesalazine.
Diclofenac Diclofenac The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Diclofenac.
Nimodipine Nimodipine The risk or severity of QTc prolongation can be increased when Nimodipine is combined with Fluoxetine.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The metabolism of Fluoxetine can be decreased when combined with Interferon alfa-2b.
Clozapine Clozapine The serum concentration of Fluoxetine can be increased when it is combined with Clozapine.
Estazolam Estazolam The serum concentration of Estazolam can be increased when it is combined with Fluoxetine.
Idarubicin Idarubicin The serum concentration of Idarubicin can be increased when it is combined with Fluoxetine.
Ofloxacin Ofloxacin The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Fluoxetine.
Clarithromycin Clarithromycin The risk or severity of QTc prolongation can be increased when Clarithromycin is combined with Fluoxetine.
Etodolac Etodolac The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Etodolac.
Felodipine Felodipine The risk or severity of QTc prolongation can be increased when Felodipine is combined with Fluoxetine.
Nabumetone Nabumetone The risk or severity of gastrointestinal bleeding can be increased when Nabumetone is combined with Fluoxetine.
Simvastatin Simvastatin The serum concentration of Fluoxetine can be increased when it is combined with Simvastatin.
Amlodipine Amlodipine The risk or severity of QTc prolongation can be increased when Amlodipine is combined with Fluoxetine.
Teniposide Injection Teniposide Injection The metabolism of Fluoxetine can be decreased when combined with Teniposide.
Itraconazole Itraconazole The risk or severity of QTc prolongation can be increased when Itraconazole is combined with Fluoxetine.
Oxaprozin Oxaprozin The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Oxaprozin.
Atovaquone Atovaquone The metabolism of Fluoxetine can be decreased when combined with Atovaquone.
Rifabutin Rifabutin The metabolism of Fluoxetine can be increased when combined with Rifabutin.
Sotalol Sotalol The serum concentration of Sotalol can be increased when it is combined with Fluoxetine.
Bisoprolol Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Fluoxetine.
Zolpidem Zolpidem Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin Doxazosin The serum concentration of Doxazosin can be increased when it is combined with Fluoxetine.
Isradipine Isradipine The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Isradipine.
Omeprazole Omeprazole The metabolism of Omeprazole can be decreased when combined with Fluoxetine.
Cisapride Cisapride The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Cisapride.
Gabapentin Gabapentin Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
Fluvastatin Fluvastatin The serum concentration of Fluvastatin can be increased when it is combined with Fluoxetine.
Venlafaxine Venlafaxine The serum concentration of Fluoxetine can be increased when it is combined with Venlafaxine.
Nizatidine Nizatidine The therapeutic efficacy of Fluoxetine can be decreased when used in combination with Nizatidine.
Fluvoxamine Fluvoxamine The serum concentration of Fluoxetine can be increased when it is combined with Fluvoxamine.
Nefazodone Nefazodone The serum concentration of Nefazodone can be increased when it is combined with Fluoxetine.
Lamotrigine Lamotrigine Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Lamotrigine.
Losartan Losartan The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Losartan.
Tramadol Tramadol The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Tramadol.
Vinorelbine Injection Vinorelbine Injection The metabolism of Fluoxetine can be decreased when combined with Vinorelbine.
Moexipril Moexipril The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Moexipril.
Lansoprazole Lansoprazole The metabolism of Fluoxetine can be decreased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Fluoxetine.
Nicardipine Nicardipine The risk or severity of QTc prolongation can be increased when Nicardipine is combined with Fluoxetine.
Bupropion Bupropion The risk or severity of seizure can be increased when Fluoxetine is combined with Bupropion.
Ticlopidine Ticlopidine The serum concentration of Ticlopidine can be increased when it is combined with Fluoxetine.
Saquinavir Saquinavir The risk or severity of QTc prolongation can be increased when Saquinavir is combined with Fluoxetine.
Metformin Metformin The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Metformin.
Dalteparin Injection Dalteparin Injection The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Dalteparin.
Riluzole Riluzole Riluzole may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Acarbose Acarbose The risk or severity of hypoglycemia can be increased when Acarbose is combined with Fluoxetine.
Glimepiride Glimepiride The metabolism of Glimepiride can be decreased when combined with Fluoxetine.
Ritonavir Ritonavir The serum concentration of Fluoxetine can be increased when it is combined with Ritonavir.
Clomipramine Clomipramine The serum concentration of Clomipramine can be increased when it is combined with Fluoxetine.
Zafirlukast Zafirlukast The metabolism of Fluoxetine can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine Fluoxetine may increase the serotonergic activities of Mirtazapine.
Topiramate Topiramate Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Topiramate.
Zileuton Zileuton The metabolism of Zileuton can be decreased when combined with Fluoxetine.
Valsartan Valsartan The metabolism of Valsartan can be decreased when combined with Fluoxetine.
Insulin Lispro Injection Insulin Lispro Injection The metabolism of Fluoxetine can be increased when combined with Insulin lispro.
Pramipexole Pramipexole Fluoxetine may increase the sedative activities of Pramipexole.
Donepezil Donepezil The therapeutic efficacy of Fluoxetine can be decreased when used in combination with Donepezil.
Nelfinavir Nelfinavir The risk or severity of QTc prolongation can be increased when Nelfinavir is combined with Fluoxetine.
Azithromycin Azithromycin The risk or severity of QTc prolongation can be increased when Azithromycin is combined with Fluoxetine.
Loratadine Loratadine The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Loratadine.
Carvedilol Carvedilol The serum concentration of Carvedilol can be increased when it is combined with Fluoxetine.
Nilutamide Nilutamide The metabolism of Fluoxetine can be decreased when combined with Nilutamide.
Flutamide Flutamide The metabolism of Flutamide can be decreased when combined with Fluoxetine.
Selegiline Selegiline The serum concentration of Selegiline can be increased when it is combined with Fluoxetine.
Bicalutamide Bicalutamide The metabolism of Fluoxetine can be decreased when combined with Bicalutamide.
Sertraline Sertraline The serum concentration of Sertraline can be increased when it is combined with Fluoxetine.
Propafenone Propafenone The serum concentration of Fluoxetine can be increased when it is combined with Propafenone.
Letrozole Letrozole The metabolism of Fluoxetine can be decreased when combined with Letrozole.
Raloxifene Raloxifene The metabolism of Fluoxetine can be decreased when combined with Raloxifene.
Irbesartan Irbesartan The metabolism of Irbesartan can be decreased when combined with Fluoxetine.
Tamsulosin Tamsulosin The serum concentration of Tamsulosin can be increased when it is combined with Fluoxetine.
Ropinirole Ropinirole The risk or severity of adverse effects can be increased when Fluoxetine is combined with Ropinirole.
Quetiapine Quetiapine The serum concentration of Quetiapine can be increased when it is combined with Fluoxetine.
Cetirizine Cetirizine Cetirizine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Paroxetine Paroxetine The serum concentration of Paroxetine can be increased when it is combined with Fluoxetine.
Tolcapone Tolcapone Tolcapone may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Citalopram Citalopram The serum concentration of Citalopram can be increased when it is combined with Fluoxetine.
Capecitabine Capecitabine The metabolism of Fluoxetine can be decreased when combined with Capecitabine.
Efavirenz Efavirenz Efavirenz may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Sildenafil Sildenafil The serum concentration of Sildenafil can be increased when it is combined with Fluoxetine.
Pioglitazone Pioglitazone The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Pioglitazone.
Celecoxib Celecoxib The risk or severity of bleeding can be increased when Celecoxib is combined with Fluoxetine.
Rosiglitazone Rosiglitazone The metabolism of Rosiglitazone can be decreased when combined with Fluoxetine.
Tolterodine Tolterodine The serum concentration of Tolterodine can be increased when it is combined with Fluoxetine.
Thalidomide Thalidomide Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Balsalazide Balsalazide The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Balsalazide.
Nateglinide Nateglinide The serum concentration of Nateglinide can be increased when it is combined with Fluoxetine.
Galantamine Galantamine The serum concentration of Fluoxetine can be increased when it is combined with Galantamine.
Levetiracetam Levetiracetam Levetiracetam may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Rabeprazole Rabeprazole The metabolism of Rabeprazole can be decreased when combined with Fluoxetine.
Terbinafine Terbinafine The metabolism of Terbinafine can be decreased when combined with Fluoxetine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists