Fostemsavir

Generic name: Pronounced as (fos tem' sa vir)
Brand names
  • Rukobia®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 08/15/2020

Fostemsavir is used along with other medications to treat human immunodeficiency virus (HIV) infection in adults whose HIV could not be successfully treated with other medications, including their current therapy. Fostemsavir is in a class of medications called HIV attachment inhibitors. It works by decreasing the amount of HIV in the blood. Although fostemsavir does not cure HIV, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer. Taking these medications along with practicing safer sex and making other life-style changes may decrease the risk of transmitting (spreading) the HIV virus to other people.

Fostemsavir comes as a tablet to take by mouth with or without food. It is usually taken twice a day. Take fostemsavir at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take fostemsavir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the tablets whole; do not split, chew, or crush them.

Fostemsavir controls HIV but does not cure it. Continue to take fostemsavir even if you feel well. Do not stop taking fostemsavir without talking to your doctor. If you miss doses or stop using fostemsavir, your condition may become more difficult to treat.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking fostemsavir,

  • tell your doctor and pharmacist if you are allergic to fostemsavir, any other medications, or any of the ingredients in fostemsavir tablets. Ask your pharmacist for a list of the ingredients.

  • tell your doctor if you are taking any of the following medications: carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), enzalutmide (Xtandi), mitotane (Lysodren), phenytoin (Dilantin, Phenytek), rifampin (Rifadin, Rimactane, in Rifamate, in Rifater), or St. John's Wort. Your doctor will probably tell you not to take fostemsavir if you are taking one or more of these medications.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention: atorvastatin (Lipitor, in Caduet), fluvastatin (Lescol), grazoprevir (in Zepatier), hormonal contraceptives (birth control pills, patches, rings, or injections), pitivastatin (Livalo, Zypitamag), rosuvastatin (Crestor, Ezallor), simvastatin (Flolipid, Zocor, in Vytorin), or voxilaprevir (in Vosevi). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with fostemsavir, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you have or have ever had prolonged QT interval (a rare heart problem that may cause fainting or irregular heartbeat), irregular heartbeat, other heart problems. Also tell your doctor if you have or have ever had hepatitis (a viral infection of the liver) or any other liver disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking fostemsavir, call your doctor. You should not breastfeed if you are infected with HIV or are taking fostemsavir.

  • you should know that while you are taking medications to treat HIV infection, your immune system may get stronger and begin to fight other infections that were already in your body. This may cause you to develop symptoms of those infections. If you have new or worsening symptoms after starting treatment with fostemsavir, be sure to tell your doctor.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Fostemsavir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • nausea

    • vomiting

    • diarrhea

    • stomach pain

    • indigestion

    • headache

    • tiredness

    • rash

    • difficulty falling asleep or staying asleep

  • Some side effects can be serious. If you experience any of these symptoms call your doctor immediately:

    • dizziness, lightheadedness, fainting, or irregular heartbeat

  • Fostemsavir may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to fostemsavir.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

Fostemsavir tablets may have a slight vinegar-like odor. Ask your pharmacist if you have any questions regarding your medication.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Moxifloxacin.
Repaglinide Repaglinide The excretion of Repaglinide can be decreased when combined with Fostemsavir.
Leflunomide Leflunomide Fostemsavir may decrease the excretion rate of Leflunomide which could result in a higher serum level.
Atorvastatin Atorvastatin The serum concentration of Atorvastatin can be increased when it is combined with Fostemsavir.
Dolasetron Dolasetron The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Dolasetron.
Anagrelide Anagrelide The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Anagrelide.
Cilostazol Cilostazol The risk or severity of QTc prolongation can be increased when Cilostazol is combined with Fostemsavir.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Fostemsavir may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Paregoric Paregoric The serum concentration of Fostemsavir can be increased when it is combined with Morphine.
Penbutolol Penbutolol The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Acebutolol.
Reserpine Reserpine The serum concentration of Fostemsavir can be increased when it is combined with Reserpine.
Sumatriptan Sumatriptan Fostemsavir may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus The serum concentration of Fostemsavir can be increased when it is combined with Tacrolimus.
Tizanidine Tizanidine The risk or severity of QTc prolongation can be increased when Tizanidine is combined with Fostemsavir.
Fluconazole Injection Fluconazole Injection The serum concentration of Fostemsavir can be increased when it is combined with Fluconazole.
Foscarnet Injection Foscarnet Injection The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Fostemsavir.
Levofloxacin Injection Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Levofloxacin.
Metoclopramide Injection Metoclopramide Injection The risk or severity of QTc prolongation can be increased when Metoclopramide is combined with Fostemsavir.
Metronidazole Injection Metronidazole Injection The risk or severity of QTc prolongation can be increased when Metronidazole is combined with Fostemsavir.
Morphine Injection Morphine Injection The serum concentration of Fostemsavir can be increased when it is combined with Morphine.
Zidovudine Injection Zidovudine Injection Fostemsavir may decrease the excretion rate of Zidovudine which could result in a higher serum level.
Cyclosporine Cyclosporine Cyclosporine may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Ondansetron Ondansetron The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Ondansetron.
Granisetron Granisetron The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Granisetron.
Torsemide Torsemide The excretion of Torasemide can be decreased when combined with Fostemsavir.
Olanzapine Olanzapine The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Fostemsavir.
Dofetilide Dofetilide The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Dofetilide.
Hydroxychloroquine Hydroxychloroquine The risk or severity of QTc prolongation can be increased when Hydroxychloroquine is combined with Fostemsavir.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Telmisartan Telmisartan Telmisartan may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Desloratadine Desloratadine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Desloratadine.
Trimipramine Trimipramine The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Fostemsavir.
Tenofovir Tenofovir The serum concentration of Tenofovir can be increased when it is combined with Fostemsavir.
Sirolimus Sirolimus The serum concentration of Sirolimus can be increased when it is combined with Fostemsavir.
Escitalopram Escitalopram The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Escitalopram.
Zonisamide Zonisamide The serum concentration of Fostemsavir can be increased when it is combined with Zonisamide.
Aripiprazole Aripiprazole The risk or severity of QTc prolongation can be increased when Aripiprazole is combined with Fostemsavir.
Atomoxetine Atomoxetine The risk or severity of QTc prolongation can be increased when Atomoxetine is combined with Fostemsavir.
Ezetimibe Ezetimibe Fostemsavir may decrease the excretion rate of Ezetimibe which could result in a higher serum level.
Mefloquine Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Fostemsavir.
Rosuvastatin Rosuvastatin The serum concentration of Rosuvastatin can be increased when it is combined with Fostemsavir.
Vardenafil Vardenafil The serum concentration of Fostemsavir can be increased when it is combined with Vardenafil.
Alfuzosin Alfuzosin The risk or severity of QTc prolongation can be increased when Alfuzosin is combined with Fostemsavir.
Tegaserod Tegaserod Fostemsavir may decrease the excretion rate of Tegaserod which could result in a higher serum level.
Gemifloxacin Gemifloxacin The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Gemifloxacin.
Progesterone Progesterone Progesterone may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Apomorphine Injection Apomorphine Injection The risk or severity of QTc prolongation can be increased when Apomorphine is combined with Fostemsavir.
Protriptyline Protriptyline The risk or severity of QTc prolongation can be increased when Protriptyline is combined with Fostemsavir.
Rifaximin Rifaximin The serum concentration of Fostemsavir can be decreased when it is combined with Rifaximin.
Bosentan Bosentan The excretion of Bosentan can be decreased when combined with Fostemsavir.
Erlotinib Erlotinib The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Erlotinib.
Solifenacin Solifenacin The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Fostemsavir.
Voriconazole Voriconazole The risk or severity of QTc prolongation can be increased when Voriconazole is combined with Fostemsavir.
Ibandronate Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Fostemsavir.
Pregabalin Pregabalin The risk or severity of QTc prolongation can be increased when Pregabalin is combined with Fostemsavir.
Tipranavir Tipranavir The serum concentration of Fostemsavir can be increased when it is combined with Tipranavir.
Felbamate Felbamate The risk or severity of QTc prolongation can be increased when Felbamate is combined with Fostemsavir.
Ranolazine Ranolazine The serum concentration of Fostemsavir can be increased when it is combined with Ranolazine.
Imatinib Imatinib The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Imatinib.
Sitagliptin Sitagliptin The serum concentration of Fostemsavir can be increased when it is combined with Sitagliptin.
Gefitinib Gefitinib Gefitinib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Albuterol Albuterol The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Fostemsavir.
Paliperidone Paliperidone The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Paliperidone.
Bortezomib Bortezomib The risk or severity of QTc prolongation can be increased when Bortezomib is combined with Fostemsavir.
Clofarabine Injection Clofarabine Injection Fostemsavir may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Oxaliplatin.
Posaconazole Posaconazole The risk or severity of QTc prolongation can be increased when Posaconazole is combined with Fostemsavir.
Primaquine Primaquine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Primaquine.
Dimenhydrinate Dimenhydrinate The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Dimenhydrinate.
Vorinostat Vorinostat The risk or severity of QTc prolongation can be increased when Vorinostat is combined with Fostemsavir.
Sorafenib Sorafenib Sorafenib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Sunitinib Sunitinib Sunitinib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Dronabinol Dronabinol Dronabinol may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Lapatinib Lapatinib The serum concentration of Fostemsavir can be increased when it is combined with Lapatinib.
Levocetirizine Levocetirizine The risk or severity of QTc prolongation can be increased when Levocetirizine is combined with Fostemsavir.
Dasatinib Dasatinib Dasatinib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Ivermectin Ivermectin Fostemsavir may decrease the excretion rate of Ivermectin which could result in a higher serum level.
Temsirolimus Temsirolimus The serum concentration of Fostemsavir can be increased when it is combined with Temsirolimus.
Nilotinib Nilotinib The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Nilotinib.
Toremifene Toremifene The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Toremifene.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Arsenic trioxide.
Mitoxantrone Injection Mitoxantrone Injection Fostemsavir may decrease the excretion rate of Mitoxantrone which could result in a higher serum level.
Bendamustine Injection Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Fostemsavir.
Flecainide Flecainide The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Flecainide.
Irinotecan Injection Irinotecan Injection Fostemsavir may decrease the excretion rate of Irinotecan which could result in a higher serum level.
Mitotane Mitotane The serum concentration of Fostemsavir can be decreased when it is combined with Mitotane.
Silodosin Silodosin The serum concentration of Fostemsavir can be increased when it is combined with Silodosin.
Eltrombopag Eltrombopag Eltrombopag may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Degarelix Injection Degarelix Injection The risk or severity of QTc prolongation can be increased when Degarelix is combined with Fostemsavir.
Betaxolol Betaxolol The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Betaxolol.
Iloperidone Iloperidone The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Iloperidone.
Everolimus Everolimus The serum concentration of Fostemsavir can be increased when it is combined with Everolimus.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The serum concentration of Fostemsavir can be increased when it is combined with Tolvaptan.
Dronedarone Dronedarone The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Dronedarone.
Pralatrexate Injection Pralatrexate Injection Fostemsavir may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Telavancin Injection Telavancin Injection The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Telavancin.
Romidepsin Injection Romidepsin Injection The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Romidepsin.
Topotecan Topotecan Fostemsavir may decrease the excretion rate of Topotecan which could result in a higher serum level.
Pazopanib Pazopanib The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Pazopanib.
Asenapine Asenapine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Asenapine.
Pitavastatin Pitavastatin The serum concentration of Pitavastatin can be increased when it is combined with Fostemsavir.
Eribulin Injection Eribulin Injection The risk or severity of QTc prolongation can be increased when Eribulin is combined with Fostemsavir.
Cabazitaxel Injection Cabazitaxel Injection Cabazitaxel may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Lurasidone Lurasidone The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Fostemsavir.
Terbutaline Injection Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Fostemsavir.
Linagliptin Linagliptin The serum concentration of Fostemsavir can be increased when it is combined with Linagliptin.
Rilpivirine Rilpivirine Rilpivirine may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Telaprevir Telaprevir Fostemsavir may decrease the excretion rate of Glecaprevir which could result in a higher serum level.
Triptorelin Injection Triptorelin Injection The risk or severity of QTc prolongation can be increased when Triptorelin is combined with Fostemsavir.
Rivaroxaban Rivaroxaban Fostemsavir may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ticagrelor Ticagrelor The serum concentration of Fostemsavir can be increased when it is combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Fostemsavir.
Vandetanib Vandetanib The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Vandetanib.
Clobazam Clobazam The serum concentration of Fostemsavir can be increased when it is combined with Clobazam.
Vemurafenib Vemurafenib The serum concentration of Vemurafenib can be increased when it is combined with Fostemsavir.
Vismodegib Vismodegib Vismodegib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Ivacaftor Ivacaftor The serum concentration of Fostemsavir can be increased when it is combined with Ivacaftor.
Axitinib Axitinib The serum concentration of Axitinib can be increased when it is combined with Fostemsavir.
Crizotinib Crizotinib The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Crizotinib.
Cabergoline Cabergoline The serum concentration of Cabergoline can be increased when it is combined with Fostemsavir.
Ambrisentan Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Fostemsavir.
Carfilzomib Injection Carfilzomib Injection The serum concentration of Fostemsavir can be increased when it is combined with Carfilzomib.
Enzalutamide Enzalutamide The serum concentration of Fostemsavir can be decreased when it is combined with Enzalutamide.
Mirabegron Mirabegron The serum concentration of Fostemsavir can be increased when it is combined with Mirabegron.
Regorafenib Regorafenib Regorafenib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Bosutinib Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Fostemsavir.
Teriflunomide Teriflunomide Teriflunomide may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Bedaquiline Bedaquiline The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Bedaquiline.
Ponatinib Ponatinib Ponatinib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Pomalidomide Pomalidomide The serum concentration of Fostemsavir can be increased when it is combined with Pomalidomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The serum concentration of Trastuzumab emtansine can be increased when it is combined with Fostemsavir.
Apixaban Apixaban Fostemsavir may decrease the excretion rate of Apixaban which could result in a higher serum level.
Canagliflozin Canagliflozin The serum concentration of Fostemsavir can be increased when it is combined with Canagliflozin.
Dabrafenib Dabrafenib Dabrafenib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Dolutegravir Dolutegravir Fostemsavir may decrease the excretion rate of Dolutegravir which could result in a higher serum level.
Afatinib Afatinib Afatinib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Lomitapide Lomitapide The serum concentration of Fostemsavir can be increased when it is combined with Lomitapide.
Simeprevir Simeprevir Simeprevir may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Sofosbuvir Sofosbuvir Fostemsavir may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Ceritinib Ceritinib The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Ceritinib.
Belinostat Injection Belinostat Injection The serum concentration of Fostemsavir can be increased when it is combined with Belinostat.
Idelalisib Idelalisib Fostemsavir may decrease the excretion rate of Idelalisib which could result in a higher serum level.
Testosterone Injection Testosterone Injection Fostemsavir may decrease the excretion rate of Testosterone which could result in a higher serum level.
Vorapaxar Vorapaxar The serum concentration of Fostemsavir can be increased when it is combined with Vorapaxar.
Suvorexant Suvorexant The serum concentration of Fostemsavir can be increased when it is combined with Suvorexant.
Edoxaban Edoxaban The serum concentration of Fostemsavir can be increased when it is combined with Edoxaban.
Olaparib Olaparib Olaparib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Caspofungin Injection Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Fostemsavir.
Riociguat Riociguat Fostemsavir may decrease the excretion rate of Riociguat which could result in a higher serum level.
Nintedanib Nintedanib The serum concentration of Fostemsavir can be increased when it is combined with Nintedanib.
Risperidone Injection Risperidone Injection The risk or severity of QTc prolongation can be increased when Risperidone is combined with Fostemsavir.
Palbociclib Palbociclib Palbociclib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Lenvatinib Lenvatinib The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Lenvatinib.
Panobinostat Panobinostat The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Panobinostat.
Haloperidol Injection Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Fostemsavir.
Ivabradine Ivabradine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Ivabradine.
Isavuconazonium Injection Isavuconazonium Injection The serum concentration of Fostemsavir can be increased when it is combined with Isavuconazonium.
Flibanserin Flibanserin The serum concentration of Fostemsavir can be increased when it is combined with Flibanserin.
Rolapitant Rolapitant Rolapitant may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Daclatasvir Daclatasvir Daclatasvir may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Ziprasidone Injection Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Ziprasidone.
Eluxadoline Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Fostemsavir.
Cobimetinib Cobimetinib The serum concentration of Cobimetinib can be increased when it is combined with Fostemsavir.
Osimertinib Osimertinib Fostemsavir may decrease the excretion rate of Osimertinib which could result in a higher serum level.
Alectinib Alectinib Alectinib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Rifapentine Rifapentine The serum concentration of Fostemsavir can be decreased when it is combined with Rifapentine.
Dexamethasone Injection Dexamethasone Injection The serum concentration of Fostemsavir can be decreased when it is combined with Dexamethasone.
Venetoclax Venetoclax Venetoclax may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Selexipag Selexipag The serum concentration of Selexipag can be increased when it is combined with Fostemsavir.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Fostemsavir.
Rucaparib Rucaparib Fostemsavir may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Ribociclib Ribociclib The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Ribociclib.
Brigatinib Brigatinib Fostemsavir may decrease the excretion rate of Brigatinib which could result in a higher serum level.
Doxepin (Insomnia) Doxepin (Insomnia) The risk or severity of QTc prolongation can be increased when Doxepin is combined with Fostemsavir.
Deutetrabenazine Deutetrabenazine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Deutetrabenazine.
Safinamide Safinamide Safinamide may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Midostaurin Midostaurin The serum concentration of Fostemsavir can be decreased when it is combined with Midostaurin.
Neratinib Neratinib The serum concentration of Fostemsavir can be increased when it is combined with Neratinib.
Enasidenib Enasidenib Fostemsavir may decrease the excretion rate of Enasidenib which could result in a higher serum level.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Fostemsavir can be increased when it is combined with Inotuzumab ozogamicin.
Copanlisib Injection Copanlisib Injection Fostemsavir may decrease the excretion rate of Copanlisib which could result in a higher serum level.
Delafloxacin Delafloxacin Fostemsavir may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib Abemaciclib Fostemsavir may decrease the excretion rate of Abemaciclib which could result in a higher serum level.
Betrixaban Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Fostemsavir.
Letermovir Letermovir Letermovir may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Tetrabenazine Tetrabenazine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Tetrabenazine.
Ertugliflozin Ertugliflozin Fostemsavir may decrease the excretion rate of Ertugliflozin which could result in a higher serum level.
Apalutamide Apalutamide The serum concentration of Fostemsavir can be decreased when it is combined with Apalutamide.
Penicillamine Penicillamine The excretion of Penicillamine can be decreased when combined with Fostemsavir.
Fostamatinib Fostamatinib Fostamatinib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Avatrombopag Avatrombopag Avatrombopag may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Baricitinib Baricitinib Baricitinib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Lofexidine Lofexidine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Lofexidine.
Eliglustat Eliglustat The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Eliglustat.
Encorafenib Encorafenib The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Encorafenib.
Binimetinib Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Fostemsavir.
Ivosidenib Ivosidenib The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Ivosidenib.
Lusutrombopag Lusutrombopag Fostemsavir may decrease the excretion rate of Lusutrombopag which could result in a higher serum level.
Elagolix Elagolix The serum concentration of Fostemsavir can be increased when it is combined with Elagolix.
Cannabidiol Cannabidiol Cannabidiol may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Dacomitinib Dacomitinib Fostemsavir may decrease the excretion rate of Dacomitinib which could result in a higher serum level.
Duvelisib Duvelisib Fostemsavir may decrease the excretion rate of Duvelisib which could result in a higher serum level.
Omadacycline Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Fostemsavir.
Sarecycline Sarecycline The serum concentration of Fostemsavir can be increased when it is combined with Sarecycline.
Talazoparib Talazoparib Fostemsavir may decrease the excretion rate of Talazoparib which could result in a higher serum level.
Gilteritinib Gilteritinib The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Gilteritinib.
Glasdegib Glasdegib The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Glasdegib.
Larotrectinib Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Fostemsavir.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The excretion of Paclitaxel can be decreased when combined with Fostemsavir.
Rifamycin Rifamycin The serum concentration of Fostemsavir can be decreased when it is combined with Rifamycin.
Erdafitinib Erdafitinib The serum concentration of Fostemsavir can be increased when it is combined with Erdafitinib.
Alpelisib Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Fostemsavir.
Cladribine Cladribine Fostemsavir may decrease the excretion rate of Cladribine which could result in a higher serum level.
Darolutamide Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Fostemsavir.
Triclabendazole Triclabendazole The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Triclabendazole.
Entrectinib Entrectinib The serum concentration of Fostemsavir can be increased when it is combined with Entrectinib.
Istradefylline Istradefylline Istradefylline may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Pitolisant Pitolisant The serum concentration of Pitolisant can be decreased when it is combined with Fostemsavir.
Fedratinib Fedratinib Fedratinib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Lefamulin Lefamulin The serum concentration of Lefamulin can be increased when it is combined with Fostemsavir.
Phenytoin Injection Phenytoin Injection The serum concentration of Fostemsavir can be decreased when it is combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The serum concentration of Fostemsavir can be decreased when it is combined with Fosphenytoin.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Fostemsavir.
Lasmiditan Lasmiditan The serum concentration of Fostemsavir can be increased when it is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Fostemsavir.
Tazemetostat Tazemetostat Fostemsavir may decrease the excretion rate of Tazemetostat which could result in a higher serum level.
Bempedoic Acid Bempedoic Acid The excretion of Bempedoic acid can be decreased when combined with Fostemsavir.
Cenobamate Cenobamate The serum concentration of Fostemsavir can be decreased when it is combined with Cenobamate.
Ozanimod Ozanimod Fostemsavir may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Selumetinib Selumetinib Fostemsavir may decrease the excretion rate of Selumetinib which could result in a higher serum level.
Rimegepant Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Fostemsavir.
Tucatinib Tucatinib Fostemsavir may decrease the excretion rate of Tucatinib which could result in a higher serum level.
Remdesivir Injection Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Fostemsavir.
Ripretinib Ripretinib Fostemsavir may decrease the excretion rate of Ripretinib which could result in a higher serum level.
Capmatinib Capmatinib The serum concentration of Fostemsavir can be increased when it is combined with Capmatinib.
Lemborexant Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Fostemsavir.
Octreotide Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Fostemsavir.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Fostemsavir.
Pralsetinib Pralsetinib Fostemsavir may decrease the excretion rate of Pralsetinib which could result in a higher serum level.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Fostemsavir can be decreased when it is combined with Satralizumab.
Relugolix Relugolix The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Relugolix.
Trazodone Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Fostemsavir.
Phenobarbital Phenobarbital The serum concentration of Fostemsavir can be decreased when it is combined with Phenobarbital.
Methotrexate Injection Methotrexate Injection Fostemsavir may decrease the excretion rate of Methotrexate which could result in a higher serum level.
Primidone Primidone The serum concentration of Fostemsavir can be decreased when it is combined with Primidone.
Methsuximide Methsuximide The risk or severity of QTc prolongation can be increased when Methsuximide is combined with Fostemsavir.
Chlorpromazine Chlorpromazine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Chlorpromazine.
Amantadine Amantadine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Fostemsavir.
Prochlorperazine Prochlorperazine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Prochlorperazine.
Thioridazine Thioridazine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Thioridazine.
Benztropine Benztropine The risk or severity of QTc prolongation can be increased when Benzatropine is combined with Fostemsavir.
Maprotiline Maprotiline The risk or severity of QTc prolongation can be increased when Maprotiline is combined with Fostemsavir.
Orphenadrine Orphenadrine The risk or severity of QTc prolongation can be increased when Orphenadrine is combined with Fostemsavir.
Amoxapine Amoxapine The risk or severity of QTc prolongation can be increased when Amoxapine is combined with Fostemsavir.
Sulfasalazine Sulfasalazine Sulfasalazine may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Doxorubicin Doxorubicin Fostemsavir may decrease the excretion rate of Doxorubicin which could result in a higher serum level.
Dactinomycin Dactinomycin Fostemsavir may decrease the excretion rate of Dactinomycin which could result in a higher serum level.
Carbamazepine Carbamazepine The serum concentration of Fostemsavir can be decreased when it is combined with Carbamazepine.
Prazosin Prazosin Fostemsavir may decrease the excretion rate of Prazosin which could result in a higher serum level.
Loperamide Loperamide The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Loperamide.
Promethazine Promethazine The risk or severity of QTc prolongation can be increased when Promethazine is combined with Fostemsavir.
Daunorubicin Daunorubicin Fostemsavir may decrease the excretion rate of Daunorubicin which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Fostemsavir may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Digoxin Digoxin The risk or severity of QTc prolongation can be increased when Digoxin is combined with Fostemsavir.
Loxapine Loxapine The serum concentration of Fostemsavir can be increased when it is combined with Loxapine.
Chloroquine Chloroquine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Chloroquine.
Quinine Quinine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Quinine.
Ethosuximide Ethosuximide The risk or severity of QTc prolongation can be increased when Ethosuximide is combined with Fostemsavir.
Desipramine Desipramine The risk or severity of QTc prolongation can be increased when Desipramine is combined with Fostemsavir.
Amitriptyline Amitriptyline The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Amitriptyline.
Imipramine Imipramine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Imipramine.
Quinidine Quinidine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Quinidine.
Procainamide Procainamide The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Procainamide.
Rifampin Rifampin The serum concentration of Fostemsavir can be decreased when it is combined with Rifampicin.
Disopyramide Disopyramide The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Disopyramide.
Valproic Acid Valproic Acid The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Valproic acid.
Tamoxifen Tamoxifen Fostemsavir may decrease the excretion rate of Tamoxifen which could result in a higher serum level.
Liothyronine Liothyronine The excretion of Liothyronine can be decreased when combined with Fostemsavir.
Dinoprostone Dinoprostone The excretion of Dinoprostone can be decreased when combined with Fostemsavir.
Doxylamine Doxylamine The risk or severity of QTc prolongation can be increased when Doxylamine is combined with Fostemsavir.
Cyproheptadine Cyproheptadine The risk or severity of QTc prolongation can be increased when Cyproheptadine is combined with Fostemsavir.
Clemastine Clemastine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Clemastine.
Chlorpheniramine Chlorpheniramine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Fostemsavir.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Hydrochlorothiazide is combined with Fostemsavir.
Folic Acid Folic Acid Fostemsavir may decrease the excretion rate of Folic acid which could result in a higher serum level.
Disulfiram Disulfiram The risk or severity of QTc prolongation can be increased when Disulfiram is combined with Fostemsavir.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Propranolol.
Nortriptyline Nortriptyline The risk or severity of QTc prolongation can be increased when Nortriptyline is combined with Fostemsavir.
Allopurinol Allopurinol Fostemsavir may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Oxytocin Injection Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Fostemsavir.
Clomiphene Clomiphene The serum concentration of Fostemsavir can be increased when it is combined with Clomifene.
Papaverine Papaverine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Papaverine.
Fluorouracil Injection Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Fluorouracil.
Colchicine Colchicine The serum concentration of Fostemsavir can be increased when it is combined with Colchicine.
Ketoconazole Ketoconazole The serum concentration of Fostemsavir can be increased when it is combined with Ketoconazole.
Vincristine Injection Vincristine Injection Fostemsavir may decrease the excretion rate of Vincristine which could result in a higher serum level.
Vinblastine Vinblastine The serum concentration of Vinblastine can be increased when it is combined with Fostemsavir.
Hydroxyzine Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Fostemsavir.
Thiothixene Thiothixene The risk or severity of QTc prolongation can be increased when Thiothixene is combined with Fostemsavir.
Hyoscyamine Hyoscyamine The risk or severity of QTc prolongation can be increased when Hyoscyamine is combined with Fostemsavir.
Diltiazem Diltiazem The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Diltiazem.
Nifedipine Nifedipine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Nifedipine.
Timolol Timolol The risk or severity of QTc prolongation can be increased when Timolol is combined with Fostemsavir.
Verapamil Verapamil The serum concentration of Fostemsavir can be increased when it is combined with Verapamil.
Etoposide Etoposide Fostemsavir may decrease the excretion rate of Etoposide which could result in a higher serum level.
Glyburide Glyburide Fostemsavir may decrease the excretion rate of Glyburide which could result in a higher serum level.
Indapamide Indapamide The risk or severity of QTc prolongation can be increased when Indapamide is combined with Fostemsavir.
Pentamidine Injection Pentamidine Injection The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Pentamidine.
Leuprolide Injection Leuprolide Injection The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Leuprolide.
Pimozide Pimozide The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Pimozide.
Enalapril Enalapril The excretion of Enalapril can be decreased when combined with Fostemsavir.
Amiodarone Amiodarone The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Amiodarone.
Lovastatin Lovastatin The serum concentration of Lovastatin can be increased when it is combined with Fostemsavir.
Ciprofloxacin Ciprofloxacin The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Ciprofloxacin.
Nimodipine Nimodipine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Nimodipine.
Clozapine Clozapine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Clozapine.
Ofloxacin Ofloxacin The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Ofloxacin.
Clarithromycin Clarithromycin The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Clarithromycin.
Felodipine Felodipine The risk or severity of QTc prolongation can be increased when Felodipine is combined with Fostemsavir.
Pravastatin Pravastatin The serum concentration of Pravastatin can be increased when it is combined with Fostemsavir.
Simvastatin Simvastatin The serum concentration of Simvastatin can be increased when it is combined with Fostemsavir.
Teniposide Injection Teniposide Injection Fostemsavir may decrease the excretion rate of Teniposide which could result in a higher serum level.
Itraconazole Itraconazole The serum concentration of Fostemsavir can be increased when it is combined with Itraconazole.
Sotalol Sotalol The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Sotalol.
Bisoprolol Bisoprolol The serum concentration of Fostemsavir can be increased when it is combined with Bisoprolol.
Isradipine Isradipine The risk or severity of QTc prolongation can be increased when Isradipine is combined with Fostemsavir.
Omeprazole Omeprazole Omeprazole may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Cisapride Cisapride The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Cisapride.
Fluvastatin Fluvastatin The serum concentration of Fluvastatin can be increased when it is combined with Fostemsavir.
Venlafaxine Venlafaxine The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Fostemsavir.
Lamotrigine Lamotrigine The risk or severity of QTc prolongation can be increased when Lamotrigine is combined with Fostemsavir.
Losartan Losartan The risk or severity of QTc prolongation can be increased when Losartan is combined with Fostemsavir.
Moexipril Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Fostemsavir.
Lansoprazole Lansoprazole Lansoprazole may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Nicardipine Nicardipine The risk or severity of QTc prolongation can be increased when Nicardipine is combined with Fostemsavir.
Saquinavir Saquinavir The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Saquinavir.
Lamivudine Lamivudine Fostemsavir may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole Riluzole Fostemsavir may decrease the excretion rate of Riluzole which could result in a higher serum level.
Gemcitabine Injection Gemcitabine Injection The serum concentration of Gemcitabine can be increased when it is combined with Fostemsavir.
Docetaxel Injection Docetaxel Injection The excretion of Docetaxel can be decreased when combined with Fostemsavir.
Clomipramine Clomipramine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Clomipramine.
Mirtazapine Mirtazapine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Fostemsavir.
Valsartan Valsartan The excretion of Valsartan can be decreased when combined with Fostemsavir.
Donepezil Donepezil Fostemsavir may decrease the excretion rate of Donepezil which could result in a higher serum level.
Nelfinavir Nelfinavir Nelfinavir may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Fexofenadine Fexofenadine The serum concentration of Fexofenadine can be increased when it is combined with Fostemsavir.
Azithromycin Azithromycin The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Azithromycin.
Carvedilol Carvedilol The serum concentration of Fostemsavir can be increased when it is combined with Carvedilol.
Propafenone Propafenone The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Propafenone.
Raloxifene Raloxifene Fostemsavir may decrease the excretion rate of Raloxifene which could result in a higher serum level.
Quetiapine Quetiapine The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Quetiapine.
Cetirizine Cetirizine The risk or severity of QTc prolongation can be increased when Cetirizine is combined with Fostemsavir.
Citalopram Citalopram The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Citalopram.
Efavirenz Efavirenz The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Efavirenz.
Sildenafil Sildenafil The serum concentration of Fostemsavir can be increased when it is combined with Sildenafil.
Celecoxib Celecoxib Fostemsavir may decrease the excretion rate of Celecoxib which could result in a higher serum level.
Tolterodine Tolterodine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Fostemsavir.
Galantamine Galantamine The risk or severity of QTc prolongation can be increased when Galantamine is combined with Fostemsavir.
Rabeprazole Rabeprazole Rabeprazole may decrease the excretion rate of Fostemsavir which could result in a higher serum level.

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