Lasmiditan

Generic name: Pronounced as (las mid' i tan)
Brand names
  • Reyvow®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 03/15/2020

Lasmiditan is used to treat the symptoms of migraine headaches (severe throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound and light). Lasmiditan is in a class of medications called selective serotonin receptor agonists. Lasmiditan may work by stopping pain signals from being sent to the brain and stopping inflammation of the nerves that cause symptoms of migraine. Lasmiditan does not prevent migraine attacks or reduce the number of headaches you have.

Lasmiditan comes as a tablet to take by mouth. It is usually taken at the first sign of a migraine headache. If your symptoms improve after you take lasmiditan but return within 24 hours, do not take a second tablet. You should not take more than one dose of lasmiditan in a 24-hour period. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take lasmiditan exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you take lasmiditan more often or for longer than the recommended period of time, your headaches may get worse or may occur more frequently. You should not take lasmiditan or any other headache medication for more than 10 days per month. Call your doctor if you need to take lasmiditan to treat more than four headaches in a 1-month period.

Lasmiditan may be habit forming. Do not take a larger dose, take it more often, or take it for a longer period of time than prescribed by your doctor.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking lasmiditan,

  • tell your doctor and pharmacist if you are allergic to lasmiditan, any other medications, or any of the ingredients in lasmiditan tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: antidepressants such as amitriptyline, amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor, Zonalon), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), and trimipramine; dextromethorphan (found in many cough medications; in Nuedexta); propranolol (Hemangeol, Inderal, Innopran); sedatives, sleeping pills, or tranquilizers; selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft); and selective serotonin/norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Pristiq), duloxetine (Cymbalta, Drizalma Sprinkle), levomilnacipran (Fetzima), and venlafaxine (Effexor). Also tell your doctor or pharmacist if you are taking the following medications or have stopped taking them within the past two weeks: isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Ensam, Zelapar), and tranylcypromine (Parnate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with lasmiditan, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor what herbal products and nutritional supplements you are taking, especially St. John's wort and tryptophan.

  • tell your doctor if you have or have ever had high blood pressure; slow, weak, or irregular heart beat; or liver problems.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking lasmiditan, call your doctor.

  • you should know that lasmiditan may make you drowsy. You should not drive a car or operate machinery for at least 8 hours after you take lasmiditan.

  • ask your doctor about the safe use of alcoholic beverages while you are taking lasmiditan. Alcohol can make the side effects from lasmiditan worse.

Unless your doctor tells you otherwise, continue your normal diet.

  • Lasmiditan may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • dizziness

    • sleepiness

    • numbness

    • tingling feeling

    • tiredness

    • nausea

    • vomiting

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

    • hallucinations (seeing thing or hearing voices that do not exist)

    • agitation

    • fast, irregular, or pounding heartbeat

    • sweating

    • trouble walking

    • tight muscles

    • sudden, nausea, vomiting. or diarrhea

    • hives

    • itching

    • wheezing or difficulty breathing or swallowing

    • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

  • Lasmiditan may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor. Your doctor may monitor your blood pressure and heart rate during your treatment with lasmiditan.

You should keep a headache diary by writing down when you have headaches and when you take lasmiditan.

Do not let anyone else take your medication. Lasmiditan is a controlled substance. Prescriptions may be refilled only a limited number of times; ask your pharmacist if you have any questions.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Leflunomide Leflunomide The serum concentration of Leflunomide can be increased when it is combined with Lasmiditan.
Dolasetron Dolasetron The risk or severity of serotonin syndrome can be increased when Dolasetron is combined with Lasmiditan.
Diphenoxylate Diphenoxylate The risk or severity of serotonin syndrome can be increased when Diphenoxylate is combined with Lasmiditan.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The serum concentration of Lasmiditan can be increased when it is combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The serum concentration of Conjugated estrogens can be increased when it is combined with Lasmiditan.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Guanfacine is combined with Lasmiditan.
Naratriptan Naratriptan The risk or severity of serotonin syndrome can be increased when Naratriptan is combined with Lasmiditan.
Paregoric Paregoric The risk or severity of serotonin syndrome can be increased when Morphine is combined with Lasmiditan.
Penbutolol Penbutolol Lasmiditan may increase the bradycardic activities of Acebutolol.
Pentazocine Pentazocine The risk or severity of serotonin syndrome can be increased when Pentazocine is combined with Lasmiditan.
Reserpine Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Lasmiditan.
Rizatriptan Rizatriptan The risk or severity of serotonin syndrome can be increased when Rizatriptan is combined with Lasmiditan.
Sumatriptan Sumatriptan The risk or severity of serotonin syndrome can be increased when Sumatriptan is combined with Lasmiditan.
Tacrolimus Tacrolimus The serum concentration of Lasmiditan can be increased when it is combined with Tacrolimus.
Tizanidine Tizanidine The risk or severity of adverse effects can be increased when Tizanidine is combined with Lasmiditan.
Zolmitriptan Zolmitriptan The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Lasmiditan.
Fluconazole Injection Fluconazole Injection The serum concentration of Lasmiditan can be increased when it is combined with Fluconazole.
Hydromorphone Injection Hydromorphone Injection The risk or severity of serotonin syndrome can be increased when Hydromorphone is combined with Lasmiditan.
Meperidine Injection Meperidine Injection The risk or severity of serotonin syndrome can be increased when Meperidine is combined with Lasmiditan.
Metoclopramide Injection Metoclopramide Injection The risk or severity of sedation can be increased when Metoclopramide is combined with Lasmiditan.
Morphine Injection Morphine Injection The risk or severity of serotonin syndrome can be increased when Morphine is combined with Lasmiditan.
Zidovudine Injection Zidovudine Injection The serum concentration of Zidovudine can be increased when it is combined with Lasmiditan.
Altretamine Altretamine The risk or severity of serotonin syndrome can be increased when Amphetamine is combined with Lasmiditan.
Cyclosporine Cyclosporine The serum concentration of Cyclosporine can be increased when it is combined with Lasmiditan.
Ondansetron Ondansetron The risk or severity of serotonin syndrome can be increased when Ondansetron is combined with Lasmiditan.
Granisetron Granisetron The risk or severity of serotonin syndrome can be increased when Granisetron is combined with Lasmiditan.
Olanzapine Olanzapine The risk or severity of serotonin syndrome can be increased when Olanzapine is combined with Lasmiditan.
Alosetron Alosetron The risk or severity of adverse effects can be increased when Alosetron is combined with Lasmiditan.
Entacapone Entacapone The risk or severity of adverse effects can be increased when Entacapone is combined with Lasmiditan.
Oxcarbazepine Oxcarbazepine The risk or severity of adverse effects can be increased when Oxcarbazepine is combined with Lasmiditan.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Zaleplon is combined with Lasmiditan.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Desloratadine is combined with Lasmiditan.
Linezolid Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Lasmiditan.
Rivastigmine Rivastigmine Lasmiditan may increase the bradycardic activities of Rivastigmine.
Trimipramine Trimipramine The risk or severity of serotonin syndrome can be increased when Trimipramine is combined with Lasmiditan.
Glycopyrrolate Glycopyrrolate Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Tenofovir Tenofovir The serum concentration of Tenofovir can be increased when it is combined with Lasmiditan.
Sirolimus Sirolimus The serum concentration of Sirolimus can be increased when it is combined with Lasmiditan.
Escitalopram Escitalopram The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Escitalopram.
Zonisamide Zonisamide The risk or severity of adverse effects can be increased when Zonisamide is combined with Lasmiditan.
Aripiprazole Aripiprazole The risk or severity of serotonin syndrome can be increased when Aripiprazole is combined with Lasmiditan.
Atomoxetine Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Lasmiditan.
Dexmethylphenidate Dexmethylphenidate The risk or severity of serotonin syndrome can be increased when Dexmethylphenidate is combined with Lasmiditan.
Ezetimibe Ezetimibe The serum concentration of Ezetimibe can be increased when it is combined with Lasmiditan.
Almotriptan Almotriptan The risk or severity of serotonin syndrome can be increased when Almotriptan is combined with Lasmiditan.
Eletriptan Eletriptan The risk or severity of serotonin syndrome can be increased when Eletriptan is combined with Lasmiditan.
Rosuvastatin Rosuvastatin The serum concentration of Rosuvastatin can be increased when it is combined with Lasmiditan.
Vardenafil Vardenafil The serum concentration of Vardenafil can be increased when it is combined with Lasmiditan.
Tegaserod Tegaserod The risk or severity of serotonin syndrome can be increased when Tegaserod is combined with Lasmiditan.
Frovatriptan Frovatriptan The risk or severity of serotonin syndrome can be increased when Frovatriptan is combined with Lasmiditan.
Apomorphine Injection Apomorphine Injection The risk or severity of serotonin syndrome can be increased when Apomorphine is combined with Lasmiditan.
Protriptyline Protriptyline The risk or severity of serotonin syndrome can be increased when Protriptyline is combined with Lasmiditan.
Rifaximin Rifaximin The serum concentration of Rifaximin can be increased when it is combined with Lasmiditan.
Duloxetine Duloxetine The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Duloxetine.
Trospium Trospium Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Lasmiditan is combined with Eszopiclone.
Solifenacin Solifenacin Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Dextroamphetamine Dextroamphetamine The risk or severity of serotonin syndrome can be increased when Amphetamine is combined with Lasmiditan.
Sodium Oxybate Sodium Oxybate The risk or severity of adverse effects can be increased when Sodium oxybate is combined with Lasmiditan.
Isocarboxazid Isocarboxazid The risk or severity of serotonin syndrome can be increased when Isocarboxazid is combined with Lasmiditan.
Ramelteon Ramelteon The risk or severity of adverse effects can be increased when Ramelteon is combined with Lasmiditan.
Darifenacin Darifenacin Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Darifenacin.
Fentanyl Fentanyl The risk or severity of serotonin syndrome can be increased when Fentanyl is combined with Lasmiditan.
Pregabalin Pregabalin The therapeutic efficacy of Lasmiditan can be increased when used in combination with Pregabalin.
Tipranavir Tipranavir The serum concentration of Lasmiditan can be increased when it is combined with Tipranavir.
Felbamate Felbamate The risk or severity of adverse effects can be increased when Felbamate is combined with Lasmiditan.
Ranolazine Ranolazine The serum concentration of Ranolazine can be increased when it is combined with Lasmiditan.
Rasagiline Rasagiline The risk or severity of serotonin syndrome can be increased when Rasagiline is combined with Lasmiditan.
Imatinib Imatinib The serum concentration of Imatinib can be increased when it is combined with Lasmiditan.
Sitagliptin Sitagliptin The serum concentration of Sitagliptin can be increased when it is combined with Lasmiditan.
Gefitinib Gefitinib The serum concentration of Gefitinib can be increased when it is combined with Lasmiditan.
Paliperidone Paliperidone The risk or severity of serotonin syndrome can be increased when Paliperidone is combined with Lasmiditan.
Bortezomib Bortezomib The serum concentration of Bortezomib can be increased when it is combined with Lasmiditan.
Clofarabine Injection Clofarabine Injection The serum concentration of Clofarabine can be increased when it is combined with Lasmiditan.
Oxaliplatin Injection Oxaliplatin Injection The serum concentration of Oxaliplatin can be increased when it is combined with Lasmiditan.
Posaconazole Posaconazole The serum concentration of Posaconazole can be increased when it is combined with Lasmiditan.
Dimenhydrinate Dimenhydrinate The risk or severity of adverse effects can be increased when Dimenhydrinate is combined with Lasmiditan.
Lisdexamfetamine Lisdexamfetamine The risk or severity of serotonin syndrome can be increased when Lisdexamfetamine is combined with Lasmiditan.
Nabilone Nabilone The risk or severity of adverse effects can be increased when Nabilone is combined with Lasmiditan.
Sorafenib Sorafenib The serum concentration of Sorafenib can be increased when it is combined with Lasmiditan.
Dronabinol Dronabinol The risk or severity of adverse effects can be increased when Dronabinol is combined with Lasmiditan.
Lapatinib Lapatinib The serum concentration of Lasmiditan can be increased when it is combined with Lapatinib.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Levocetirizine is combined with Lasmiditan.
Dasatinib Dasatinib The serum concentration of Dasatinib can be increased when it is combined with Lasmiditan.
Ivermectin Ivermectin The serum concentration of Ivermectin can be increased when it is combined with Lasmiditan.
Temsirolimus Temsirolimus The serum concentration of Temsirolimus can be increased when it is combined with Lasmiditan.
Nilotinib Nilotinib The serum concentration of Nilotinib can be increased when it is combined with Lasmiditan.
Toremifene Toremifene The serum concentration of Toremifene can be increased when it is combined with Lasmiditan.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Lasmiditan.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Lasmiditan.
Mitoxantrone Injection Mitoxantrone Injection The serum concentration of Mitoxantrone can be increased when it is combined with Lasmiditan.
Desvenlafaxine Desvenlafaxine The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Desvenlafaxine.
Nebivolol Nebivolol Lasmiditan may increase the bradycardic activities of Nebivolol.
Bendamustine Injection Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Lasmiditan.
Irinotecan Injection Irinotecan Injection The serum concentration of Irinotecan can be increased when it is combined with Lasmiditan.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Lasmiditan.
Silodosin Silodosin The serum concentration of Silodosin can be increased when it is combined with Lasmiditan.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Midazolam is combined with Lasmiditan.
Naltrexone Injection Naltrexone Injection The risk or severity of serotonin syndrome can be increased when Naltrexone is combined with Lasmiditan.
Milnacipran Milnacipran The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Milnacipran.
Fesoterodine Fesoterodine Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Betaxolol Betaxolol Lasmiditan may increase the bradycardic activities of Betaxolol.
Iloperidone Iloperidone The risk or severity of serotonin syndrome can be increased when Iloperidone is combined with Lasmiditan.
Lacosamide Lacosamide The risk or severity of adverse effects can be increased when Lacosamide is combined with Lasmiditan.
Everolimus Everolimus The serum concentration of Everolimus can be increased when it is combined with Lasmiditan.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The serum concentration of Tolvaptan can be increased when it is combined with Lasmiditan.
Dronedarone Dronedarone Lasmiditan may increase the bradycardic activities of Dronedarone.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Lasmiditan.
Pralatrexate Injection Pralatrexate Injection The serum concentration of Pralatrexate can be increased when it is combined with Lasmiditan.
Palonosetron Injection Palonosetron Injection The risk or severity of serotonin syndrome can be increased when Palonosetron is combined with Lasmiditan.
Romidepsin Injection Romidepsin Injection The serum concentration of Romidepsin can be increased when it is combined with Lasmiditan.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Lasmiditan.
Topotecan Topotecan The serum concentration of Topotecan can be increased when it is combined with Lasmiditan.
Pazopanib Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Lasmiditan.
Asenapine Asenapine The risk or severity of serotonin syndrome can be increased when Asenapine is combined with Lasmiditan.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Vigabatrin is combined with Lasmiditan.
Pitavastatin Pitavastatin The serum concentration of Pitavastatin can be increased when it is combined with Lasmiditan.
Oxymorphone Oxymorphone The risk or severity of serotonin syndrome can be increased when Oxymorphone is combined with Lasmiditan.
Fingolimod Fingolimod Lasmiditan may increase the bradycardic activities of Fingolimod.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Lasmiditan.
Cabazitaxel Injection Cabazitaxel Injection The serum concentration of Cabazitaxel can be increased when it is combined with Lasmiditan.
Lurasidone Lurasidone The risk or severity of serotonin syndrome can be increased when Lurasidone is combined with Lasmiditan.
Vilazodone Vilazodone The risk or severity of serotonin syndrome can be increased when Vilazodone is combined with Lasmiditan.
Linagliptin Linagliptin The serum concentration of Linagliptin can be increased when it is combined with Lasmiditan.
Telaprevir Telaprevir The serum concentration of Glecaprevir can be increased when it is combined with Lasmiditan.
Rivaroxaban Rivaroxaban The serum concentration of Rivaroxaban can be increased when it is combined with Lasmiditan.
Ticagrelor Ticagrelor The serum concentration of Ticagrelor can be increased when it is combined with Lasmiditan.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Lasmiditan.
Vandetanib Vandetanib The serum concentration of Lasmiditan can be increased when it is combined with Vandetanib.
Clobazam Clobazam The serum concentration of Lasmiditan can be increased when it is combined with Clobazam.
Vemurafenib Vemurafenib The serum concentration of Vemurafenib can be increased when it is combined with Lasmiditan.
Ivacaftor Ivacaftor The serum concentration of Lasmiditan can be increased when it is combined with Ivacaftor.
Axitinib Axitinib The serum concentration of Axitinib can be increased when it is combined with Lasmiditan.
Crizotinib Crizotinib The serum concentration of Crizotinib can be increased when it is combined with Lasmiditan.
Cabergoline Cabergoline The risk or severity of serotonin syndrome can be increased when Cabergoline is combined with Lasmiditan.
Ambrisentan Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Lasmiditan.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Tiagabine is combined with Lasmiditan.
Carfilzomib Injection Carfilzomib Injection The serum concentration of Lasmiditan can be increased when it is combined with Carfilzomib.
Enzalutamide Enzalutamide The serum concentration of Lasmiditan can be increased when it is combined with Enzalutamide.
Mirabegron Mirabegron The serum concentration of Mirabegron can be increased when it is combined with Lasmiditan.
Regorafenib Regorafenib Regorafenib may increase the bradycardic activities of Lasmiditan.
Bosutinib Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Lasmiditan.
Teriflunomide Teriflunomide The serum concentration of Teriflunomide can be increased when it is combined with Lasmiditan.
Tofacitinib Tofacitinib Lasmiditan may increase the bradycardic activities of Tofacitinib.
Ponatinib Ponatinib The serum concentration of Lasmiditan can be increased when it is combined with Ponatinib.
Pomalidomide Pomalidomide The serum concentration of Lasmiditan can be increased when it is combined with Pomalidomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The serum concentration of Trastuzumab emtansine can be increased when it is combined with Lasmiditan.
Apixaban Apixaban The serum concentration of Apixaban can be increased when it is combined with Lasmiditan.
Canagliflozin Canagliflozin The serum concentration of Canagliflozin can be increased when it is combined with Lasmiditan.
Dabrafenib Dabrafenib The serum concentration of Dabrafenib can be increased when it is combined with Lasmiditan.
Dolutegravir Dolutegravir The serum concentration of Dolutegravir can be increased when it is combined with Lasmiditan.
Afatinib Afatinib The serum concentration of Afatinib can be increased when it is combined with Lasmiditan.
Levomilnacipran Levomilnacipran The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Levomilnacipran.
Vortioxetine Vortioxetine The risk or severity of serotonin syndrome can be increased when Vortioxetine is combined with Lasmiditan.
Perampanel Perampanel The risk or severity of adverse effects can be increased when Perampanel is combined with Lasmiditan.
Lomitapide Lomitapide The serum concentration of Lasmiditan can be increased when it is combined with Lomitapide.
Simeprevir Simeprevir The serum concentration of Simeprevir can be increased when it is combined with Lasmiditan.
Sofosbuvir Sofosbuvir The serum concentration of Sofosbuvir can be increased when it is combined with Lasmiditan.
Ceritinib Ceritinib The serum concentration of Ceritinib can be increased when it is combined with Lasmiditan.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Lasmiditan is combined with Eslicarbazepine.
Belinostat Injection Belinostat Injection The serum concentration of Belinostat can be increased when it is combined with Lasmiditan.
Idelalisib Idelalisib The serum concentration of Idelalisib can be increased when it is combined with Lasmiditan.
Testosterone Injection Testosterone Injection The serum concentration of Testosterone can be increased when it is combined with Lasmiditan.
Vorapaxar Vorapaxar The serum concentration of Lasmiditan can be increased when it is combined with Vorapaxar.
Hydrocodone Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Lasmiditan.
Suvorexant Suvorexant Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Edoxaban Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Lasmiditan.
Methamphetamine Methamphetamine The risk or severity of serotonin syndrome can be increased when Metamfetamine is combined with Lasmiditan.
Tasimelteon Tasimelteon The risk or severity of adverse effects can be increased when Tasimelteon is combined with Lasmiditan.
Riociguat Riociguat The serum concentration of Riociguat can be increased when it is combined with Lasmiditan.
Lanreotide Injection Lanreotide Injection Lasmiditan may increase the bradycardic activities of Lanreotide.
Nintedanib Nintedanib The serum concentration of Nintedanib can be increased when it is combined with Lasmiditan.
Risperidone Injection Risperidone Injection The risk or severity of serotonin syndrome can be increased when Risperidone is combined with Lasmiditan.
Palbociclib Palbociclib The serum concentration of Palbociclib can be increased when it is combined with Lasmiditan.
Lenvatinib Lenvatinib The serum concentration of Lenvatinib can be increased when it is combined with Lasmiditan.
Naloxegol Naloxegol The serum concentration of Naloxegol can be increased when it is combined with Lasmiditan.
Panobinostat Panobinostat The serum concentration of Panobinostat can be increased when it is combined with Lasmiditan.
Haloperidol Injection Haloperidol Injection The risk or severity of CNS depression can be increased when Haloperidol is combined with Lasmiditan.
Ivabradine Ivabradine Lasmiditan may increase the bradycardic activities of Ivabradine.
Isavuconazonium Injection Isavuconazonium Injection The serum concentration of Lasmiditan can be increased when it is combined with Isavuconazonium.
Flibanserin Flibanserin The risk or severity of serotonin syndrome can be increased when Flibanserin is combined with Lasmiditan.
Rolapitant Rolapitant The serum concentration of Lasmiditan can be increased when it is combined with Rolapitant.
Daclatasvir Daclatasvir The serum concentration of Lasmiditan can be increased when it is combined with Daclatasvir.
Brexpiprazole Brexpiprazole The risk or severity of serotonin syndrome can be increased when Brexpiprazole is combined with Lasmiditan.
Ziprasidone Injection Ziprasidone Injection The risk or severity of serotonin syndrome can be increased when Ziprasidone is combined with Lasmiditan.
Cariprazine Cariprazine The risk or severity of serotonin syndrome can be increased when Cariprazine is combined with Lasmiditan.
Eluxadoline Eluxadoline The risk or severity of serotonin syndrome can be increased when Eluxadoline is combined with Lasmiditan.
Cobimetinib Cobimetinib The serum concentration of Cobimetinib can be increased when it is combined with Lasmiditan.
Osimertinib Osimertinib The serum concentration of Osimertinib can be increased when it is combined with Lasmiditan.
Brivaracetam Injection Brivaracetam Injection The risk or severity of adverse effects can be increased when Brivaracetam is combined with Lasmiditan.
Venetoclax Venetoclax The serum concentration of Venetoclax can be increased when it is combined with Lasmiditan.
Cobicistat Cobicistat The serum concentration of Lasmiditan can be increased when it is combined with Cobicistat.
Midodrine Midodrine Lasmiditan may increase the bradycardic activities of Midodrine.
Selexipag Selexipag The serum concentration of Selexipag can be increased when it is combined with Lasmiditan.
Pimavanserin Pimavanserin The risk or severity of serotonin syndrome can be increased when Pimavanserin is combined with Lasmiditan.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of serotonin syndrome can be increased when Diphenhydramine is combined with Lasmiditan.
Rucaparib Rucaparib The serum concentration of Rucaparib can be increased when it is combined with Lasmiditan.
Brigatinib Brigatinib The serum concentration of Brigatinib can be increased when it is combined with Lasmiditan.
Doxepin (Insomnia) Doxepin (Insomnia) The risk or severity of serotonin syndrome can be increased when Doxepin is combined with Lasmiditan.
Safinamide Safinamide The risk or severity of serotonin syndrome can be increased when Safinamide is combined with Lasmiditan.
Neratinib Neratinib The serum concentration of Lasmiditan can be increased when it is combined with Neratinib.
Enasidenib Enasidenib The serum concentration of Enasidenib can be increased when it is combined with Lasmiditan.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Inotuzumab ozogamicin can be increased when it is combined with Lasmiditan.
Copanlisib Injection Copanlisib Injection The serum concentration of Copanlisib can be increased when it is combined with Lasmiditan.
Delafloxacin Delafloxacin The serum concentration of Delafloxacin can be increased when it is combined with Lasmiditan.
Abemaciclib Abemaciclib The serum concentration of Abemaciclib can be increased when it is combined with Lasmiditan.
Betrixaban Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Lasmiditan.
Ertugliflozin Ertugliflozin The serum concentration of Ertugliflozin can be increased when it is combined with Lasmiditan.
Buprenorphine Injection Buprenorphine Injection Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Apalutamide Apalutamide The serum concentration of Lasmiditan can be decreased when it is combined with Apalutamide.
Avatrombopag Avatrombopag The serum concentration of Avatrombopag can be increased when it is combined with Lasmiditan.
Baricitinib Baricitinib The serum concentration of Baricitinib can be increased when it is combined with Lasmiditan.
Lofexidine Lofexidine The therapeutic efficacy of Lasmiditan can be increased when used in combination with Lofexidine.
Eliglustat Eliglustat The serum concentration of Lasmiditan can be increased when it is combined with Eliglustat.
Binimetinib Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Lasmiditan.
Ivosidenib Ivosidenib The serum concentration of Ivosidenib can be increased when it is combined with Lasmiditan.
Lusutrombopag Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Lasmiditan.
Elagolix Elagolix The serum concentration of Elagolix can be increased when it is combined with Lasmiditan.
Cannabidiol Cannabidiol The risk or severity of serotonin syndrome can be increased when Cannabidiol is combined with Lasmiditan.
Dacomitinib Dacomitinib The serum concentration of Dacomitinib can be increased when it is combined with Lasmiditan.
Duvelisib Duvelisib The serum concentration of Duvelisib can be increased when it is combined with Lasmiditan.
Omadacycline Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Lasmiditan.
Sarecycline Sarecycline The serum concentration of Lasmiditan can be increased when it is combined with Sarecycline.
Stiripentol Stiripentol The risk or severity of adverse effects can be increased when Stiripentol is combined with Lasmiditan.
Talazoparib Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Lasmiditan.
Gilteritinib Gilteritinib The serum concentration of Lasmiditan can be increased when it is combined with Gilteritinib.
Glasdegib Glasdegib The serum concentration of Glasdegib can be increased when it is combined with Lasmiditan.
Larotrectinib Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Lasmiditan.
Rifamycin Rifamycin The serum concentration of Rifamycin can be increased when it is combined with Lasmiditan.
Prucalopride Prucalopride The serum concentration of Prucalopride can be increased when it is combined with Lasmiditan.
Erdafitinib Erdafitinib The serum concentration of Lasmiditan can be increased when it is combined with Erdafitinib.
Alpelisib Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Lasmiditan.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Lasmiditan is combined with Brexanolone.
Cladribine Cladribine The serum concentration of Cladribine can be increased when it is combined with Lasmiditan.
Solriamfetol Solriamfetol The risk or severity of adverse effects can be increased when Lasmiditan is combined with Solriamfetol.
Darolutamide Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Lasmiditan.
Entrectinib Entrectinib The serum concentration of Lasmiditan can be increased when it is combined with Entrectinib.
Istradefylline Istradefylline The serum concentration of Lasmiditan can be increased when it is combined with Istradefylline.
Pitolisant Pitolisant The serum concentration of Lasmiditan can be increased when it is combined with Pitolisant.
Fedratinib Fedratinib The serum concentration of Fedratinib can be increased when it is combined with Lasmiditan.
Lefamulin Lefamulin Lasmiditan may decrease the excretion rate of Lefamulin which could result in a higher serum level.
Phenytoin Injection Phenytoin Injection The risk or severity of adverse effects can be increased when Phenytoin is combined with Lasmiditan.
Fosphenytoin Injection Fosphenytoin Injection The risk or severity of adverse effects can be increased when Fosphenytoin is combined with Lasmiditan.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Lasmiditan.
Lumateperone Lumateperone The risk or severity of adverse effects can be increased when Lumateperone is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Lasmiditan.
Tazemetostat Tazemetostat The serum concentration of Tazemetostat can be increased when it is combined with Lasmiditan.
Ozanimod Ozanimod Lasmiditan may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Selumetinib Selumetinib The serum concentration of Selumetinib can be increased when it is combined with Lasmiditan.
Rimegepant Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Lasmiditan.
Tucatinib Tucatinib The serum concentration of Tucatinib can be increased when it is combined with Lasmiditan.
Remdesivir Injection Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Lasmiditan.
Ripretinib Ripretinib The serum concentration of Ripretinib can be increased when it is combined with Lasmiditan.
Lemborexant Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Lasmiditan.
Fenfluramine Fenfluramine The risk or severity of serotonin syndrome can be increased when Fenfluramine is combined with Lasmiditan.
Fostemsavir Fostemsavir The serum concentration of Fostemsavir can be increased when it is combined with Lasmiditan.
Octreotide Octreotide Lasmiditan may increase the bradycardic activities of Octreotide.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Lasmiditan.
Pralsetinib Pralsetinib The serum concentration of Pralsetinib can be increased when it is combined with Lasmiditan.
Relugolix Relugolix The serum concentration of Relugolix can be increased when it is combined with Lasmiditan.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Viloxazine is combined with Lasmiditan.
Trazodone Trazodone The risk or severity of serotonin syndrome can be increased when Trazodone is combined with Lasmiditan.
Phenobarbital Phenobarbital The risk or severity of adverse effects can be increased when Phenobarbital is combined with Lasmiditan.
Metaxalone Metaxalone The risk or severity of serotonin syndrome can be increased when Metaxalone is combined with Lasmiditan.
Methotrexate Injection Methotrexate Injection The serum concentration of Methotrexate can be increased when it is combined with Lasmiditan.
Levorphanol Levorphanol The risk or severity of serotonin syndrome can be increased when Levorphanol is combined with Lasmiditan.
Primidone Primidone The risk or severity of adverse effects can be increased when Primidone is combined with Lasmiditan.
Methsuximide Methsuximide The risk or severity of adverse effects can be increased when Methsuximide is combined with Lasmiditan.
Diethylpropion Diethylpropion The risk or severity of serotonin syndrome can be increased when Diethylpropion is combined with Lasmiditan.
Chlorpromazine Chlorpromazine The risk or severity of serotonin syndrome can be increased when Chlorpromazine is combined with Lasmiditan.
Diazepam Diazepam The risk or severity of adverse effects can be increased when Diazepam is combined with Lasmiditan.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Oxazepam is combined with Lasmiditan.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Flurazepam is combined with Lasmiditan.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Clorazepic acid is combined with Lasmiditan.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Lasmiditan.
Amantadine Amantadine The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Lasmiditan.
Codeine Codeine The risk or severity of serotonin syndrome can be increased when Codeine is combined with Lasmiditan.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Lasmiditan.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Lasmiditan.
Bromocriptine Bromocriptine The risk or severity of adverse effects can be increased when Bromocriptine is combined with Lasmiditan.
Tranylcypromine Tranylcypromine The risk or severity of serotonin syndrome can be increased when Tranylcypromine is combined with Lasmiditan.
Phenelzine Phenelzine The risk or severity of serotonin syndrome can be increased when Phenelzine is combined with Lasmiditan.
Procarbazine Procarbazine The risk or severity of serotonin syndrome can be increased when Procarbazine is combined with Lasmiditan.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of serotonin syndrome can be increased when Ergoloid mesylate is combined with Lasmiditan.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Lasmiditan.
Prochlorperazine Prochlorperazine The risk or severity of adverse effects can be increased when Prochlorperazine is combined with Lasmiditan.
Thioridazine Thioridazine The risk or severity of serotonin syndrome can be increased when Thioridazine is combined with Lasmiditan.
Trifluoperazine Trifluoperazine The risk or severity of adverse effects can be increased when Trifluoperazine is combined with Lasmiditan.
Oxycodone Oxycodone The risk or severity of serotonin syndrome can be increased when Oxycodone is combined with Lasmiditan.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Lasmiditan.
Oxybutynin Oxybutynin Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin.
Benztropine Benztropine Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Benzatropine.
Maprotiline Maprotiline The risk or severity of serotonin syndrome can be increased when Maprotiline is combined with Lasmiditan.
Trihexyphenidyl Trihexyphenidyl Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine Orphenadrine The risk or severity of adverse effects can be increased when Lasmiditan is combined with Orphenadrine.
Perphenazine Perphenazine The risk or severity of adverse effects can be increased when Perphenazine is combined with Lasmiditan.
Fluphenazine Fluphenazine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Lasmiditan.
Phentermine Phentermine The risk or severity of serotonin syndrome can be increased when Phentermine is combined with Lasmiditan.
Amoxapine Amoxapine The risk or severity of serotonin syndrome can be increased when Amoxapine is combined with Lasmiditan.
Sulfasalazine Sulfasalazine The serum concentration of Sulfasalazine can be increased when it is combined with Lasmiditan.
Doxorubicin Doxorubicin The serum concentration of Doxorubicin can be increased when it is combined with Lasmiditan.
Dactinomycin Dactinomycin The serum concentration of Dactinomycin can be increased when it is combined with Lasmiditan.
Carbamazepine Carbamazepine The risk or severity of serotonin syndrome can be increased when Carbamazepine is combined with Lasmiditan.
Molindone Molindone The risk or severity of adverse effects can be increased when Molindone is combined with Lasmiditan.
Methyldopa Methyldopa Lasmiditan may increase the bradycardic activities of Methyldopa.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Lasmiditan.
Prazosin Prazosin The serum concentration of Prazosin can be increased when it is combined with Lasmiditan.
Clonazepam Clonazepam The risk or severity of adverse effects can be increased when Clonazepam is combined with Lasmiditan.
Loperamide Loperamide The serum concentration of Loperamide can be increased when it is combined with Lasmiditan.
Promethazine Promethazine The risk or severity of serotonin syndrome can be increased when Promethazine is combined with Lasmiditan.
Daunorubicin Daunorubicin The serum concentration of Daunorubicin can be increased when it is combined with Lasmiditan.
Nitrofurantoin Nitrofurantoin The serum concentration of Nitrofurantoin can be increased when it is combined with Lasmiditan.
Digoxin Digoxin The serum concentration of Digoxin can be increased when it is combined with Lasmiditan.
Loxapine Loxapine The risk or severity of serotonin syndrome can be increased when Loxapine is combined with Lasmiditan.
Quinine Quinine The serum concentration of Lasmiditan can be increased when it is combined with Quinine.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Ethosuximide is combined with Lasmiditan.
Secobarbital Secobarbital The risk or severity of adverse effects can be increased when Secobarbital is combined with Lasmiditan.
Desipramine Desipramine The risk or severity of serotonin syndrome can be increased when Desipramine is combined with Lasmiditan.
Amitriptyline Amitriptyline The risk or severity of serotonin syndrome can be increased when Amitriptyline is combined with Lasmiditan.
Imipramine Imipramine The risk or severity of serotonin syndrome can be increased when Imipramine is combined with Lasmiditan.
Quinidine Quinidine The serum concentration of Quinidine can be increased when it is combined with Lasmiditan.
Isoniazid Isoniazid The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Lasmiditan.
Disopyramide Disopyramide Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Disopyramide.
Valproic Acid Valproic Acid The risk or severity of serotonin syndrome can be increased when Valproic acid is combined with Lasmiditan.
Tamoxifen Tamoxifen The serum concentration of Tamoxifen can be increased when it is combined with Lasmiditan.
Butabarbital Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Lasmiditan.
Dextromethorphan Dextromethorphan The risk or severity of serotonin syndrome can be increased when Dextromethorphan is combined with Lasmiditan.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Cyclobenzaprine is combined with Lasmiditan.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Lasmiditan.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Lasmiditan.
Cyproheptadine Cyproheptadine The risk or severity of adverse effects can be increased when Cyproheptadine is combined with Lasmiditan.
Clemastine Clemastine The risk or severity of adverse effects can be increased when Clemastine is combined with Lasmiditan.
Chlorpheniramine Chlorpheniramine The risk or severity of serotonin syndrome can be increased when Chlorpheniramine is combined with Lasmiditan.
Brompheniramine Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Lasmiditan.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Meclizine is combined with Lasmiditan.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Dantrolene is combined with Lasmiditan.
Chlorzoxazone Chlorzoxazone The risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Lasmiditan.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Lasmiditan.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Methocarbamol is combined with Lasmiditan.
Folic Acid Folic Acid The serum concentration of Folic acid can be increased when it is combined with Lasmiditan.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) Lasmiditan may increase the bradycardic activities of Propranolol.
Pseudoephedrine Pseudoephedrine The risk or severity of serotonin syndrome can be increased when Pseudoephedrine is combined with Lasmiditan.
Nortriptyline Nortriptyline The risk or severity of serotonin syndrome can be increased when Nortriptyline is combined with Lasmiditan.
Nadolol Nadolol Lasmiditan may increase the bradycardic activities of Nadolol.
Butorphanol Injection Butorphanol Injection The risk or severity of serotonin syndrome can be increased when Butorphanol is combined with Lasmiditan.
Nalbuphine Injection Nalbuphine Injection The risk or severity of serotonin syndrome can be increased when Nalbuphine is combined with Lasmiditan.
Allopurinol Allopurinol The serum concentration of Allopurinol can be increased when it is combined with Lasmiditan.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Lasmiditan.
Clomiphene Clomiphene The serum concentration of Clomifene can be increased when it is combined with Lasmiditan.
Flavoxate Flavoxate Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Fluorouracil Injection Fluorouracil Injection The serum concentration of Fluorouracil can be increased when it is combined with Lasmiditan.
Colchicine Colchicine The serum concentration of Colchicine can be increased when it is combined with Lasmiditan.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Acetazolamide is combined with Lasmiditan.
Ketoconazole Ketoconazole The serum concentration of Lasmiditan can be increased when it is combined with Ketoconazole.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Pyrantel is combined with Lasmiditan.
Vincristine Injection Vincristine Injection The serum concentration of Vincristine can be increased when it is combined with Lasmiditan.
Vinblastine Vinblastine The serum concentration of Vinblastine can be increased when it is combined with Lasmiditan.
Metoprolol Metoprolol Lasmiditan may increase the bradycardic activities of Metoprolol.
Hydroxyzine Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Lasmiditan.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Thiothixene is combined with Lasmiditan.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Lasmiditan.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Lasmiditan.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Triazolam is combined with Lasmiditan.
Dicyclomine Dicyclomine Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine Hyoscyamine Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline Propantheline Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Diltiazem Diltiazem Lasmiditan may increase the bradycardic activities of Diltiazem.
Nifedipine Nifedipine Lasmiditan may increase the bradycardic activities of Nifedipine.
Timolol Timolol Lasmiditan may increase the bradycardic activities of Timolol.
Verapamil Verapamil Verapamil may increase the bradycardic activities of Lasmiditan.
Atenolol Atenolol Lasmiditan may increase the bradycardic activities of Atenolol.
Pindolol Pindolol The risk or severity of serotonin syndrome can be increased when Pindolol is combined with Lasmiditan.
Etoposide Etoposide The serum concentration of Etoposide can be increased when it is combined with Lasmiditan.
Glyburide Glyburide The serum concentration of Glyburide can be increased when it is combined with Lasmiditan.
Labetalol Labetalol Lasmiditan may increase the bradycardic activities of Labetalol.
Pimozide Pimozide The risk or severity of adverse effects can be increased when Pimozide is combined with Lasmiditan.
Amiodarone Amiodarone Lasmiditan may increase the bradycardic activities of Amiodarone.
Buspirone Buspirone The risk or severity of serotonin syndrome can be increased when Buspirone is combined with Lasmiditan.
Fluoxetine Fluoxetine The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Fluoxetine.
Nimodipine Nimodipine Lasmiditan may increase the bradycardic activities of Nimodipine.
Clozapine Clozapine The risk or severity of adverse effects can be increased when Lasmiditan is combined with Clozapine.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Estazolam is combined with Lasmiditan.
Clarithromycin Clarithromycin The serum concentration of Lasmiditan can be increased when it is combined with Clarithromycin.
Felodipine Felodipine Lasmiditan may increase the bradycardic activities of Felodipine.
Pravastatin Pravastatin The serum concentration of Pravastatin can be increased when it is combined with Lasmiditan.
Simvastatin Simvastatin The serum concentration of Simvastatin can be increased when it is combined with Lasmiditan.
Amlodipine Amlodipine Lasmiditan may increase the bradycardic activities of Amlodipine.
Teniposide Injection Teniposide Injection The serum concentration of Teniposide can be increased when it is combined with Lasmiditan.
Itraconazole Itraconazole The serum concentration of Lasmiditan can be increased when it is combined with Itraconazole.
Sotalol Sotalol Lasmiditan may increase the bradycardic activities of Sotalol.
Bisoprolol Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Lasmiditan.
Zolpidem Zolpidem Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Isradipine Isradipine Lasmiditan may increase the bradycardic activities of Isradipine.
Cisapride Cisapride The risk or severity of serotonin syndrome can be increased when Cisapride is combined with Lasmiditan.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Gabapentin is combined with Lasmiditan.
Venlafaxine Venlafaxine The risk or severity of serotonin syndrome can be increased when Venlafaxine is combined with Lasmiditan.
Fluvoxamine Fluvoxamine The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Fluvoxamine.
Nefazodone Nefazodone The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Nefazodone.
Lamotrigine Lamotrigine The risk or severity of adverse effects can be increased when Lasmiditan is combined with Lamotrigine.
Tramadol Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Lasmiditan.
Nicardipine Nicardipine Lasmiditan may increase the bradycardic activities of Nicardipine.
Bupropion Bupropion The risk or severity of adverse effects can be increased when Bupropion is combined with Lasmiditan.
Saquinavir Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Lasmiditan.
Nisoldipine Nisoldipine Lasmiditan may increase the bradycardic activities of Nisoldipine.
Lamivudine Lamivudine The serum concentration of Lamivudine can be increased when it is combined with Lasmiditan.
Riluzole Riluzole The serum concentration of Lasmiditan can be increased when it is combined with Riluzole.
Gemcitabine Injection Gemcitabine Injection The serum concentration of Gemcitabine can be increased when it is combined with Lasmiditan.
Ritonavir Ritonavir The serum concentration of Lasmiditan can be increased when it is combined with Ritonavir.
Clomipramine Clomipramine The risk or severity of serotonin syndrome can be increased when Clomipramine is combined with Lasmiditan.
Mirtazapine Mirtazapine Lasmiditan may increase the serotonergic activities of Mirtazapine.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Lasmiditan.
Pramipexole Pramipexole Lasmiditan may increase the sedative activities of Pramipexole.
Donepezil Donepezil The serum concentration of Donepezil can be increased when it is combined with Lasmiditan.
Fexofenadine Fexofenadine The serum concentration of Lasmiditan can be increased when it is combined with Fexofenadine.
Carvedilol Carvedilol Lasmiditan may increase the bradycardic activities of Carvedilol.
Selegiline Selegiline The risk or severity of serotonin syndrome can be increased when Selegiline is combined with Lasmiditan.
Sertraline Sertraline The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Sertraline.
Propafenone Propafenone Lasmiditan may increase the bradycardic activities of Propafenone.
Raloxifene Raloxifene The serum concentration of Raloxifene can be increased when it is combined with Lasmiditan.
Ropinirole Ropinirole The risk or severity of adverse effects can be increased when Lasmiditan is combined with Ropinirole.
Quetiapine Quetiapine The risk or severity of serotonin syndrome can be increased when Quetiapine is combined with Lasmiditan.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Lasmiditan.
Paroxetine Paroxetine The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Paroxetine.
Tolcapone Tolcapone The risk or severity of adverse effects can be increased when Tolcapone is combined with Lasmiditan.
Citalopram Citalopram The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Citalopram.
Efavirenz Efavirenz The risk or severity of adverse effects can be increased when Efavirenz is combined with Lasmiditan.
Sildenafil Sildenafil The serum concentration of Sildenafil can be increased when it is combined with Lasmiditan.
Celecoxib Celecoxib The serum concentration of Celecoxib can be increased when it is combined with Lasmiditan.
Tolterodine Tolterodine Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
Thalidomide Thalidomide Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Galantamine Galantamine Lasmiditan may increase the bradycardic activities of Galantamine.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Levetiracetam is combined with Lasmiditan.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists