Lurasidone

Generic name: Pronounced as (loo ras' I done )
Brand names
  • Latuda®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 04/15/2018

Important warning for older adults with dementia:

Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take antipsychotics (medications for mental illness) such as lurasidone have an increased chance of death during treatment. Older adults with dementia may also have a greater chance of having a stroke or ministroke during treatment with antipsychotics.

Lurasidone is not approved by the Food and Drug Administration (FDA) for the treatment of behavior disorders in older adults with dementia. Talk to the doctor who prescribed this medication if you, a family member, or someone you care for has dementia and is taking lurasidone. For more information visit the FDA website: http://www.fda.gov/Drugs

Important warning for people who have depression:

A small number of children, teenagers, and young adults (up to 24 years of age) who took medications for depression during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. However, experts are not sure about how great this risk is and how much it should be considered in deciding whether a child or teenager should take an antidepressant. Children younger than 10 years of age should not normally take lurasidone to treat depression, but in some cases, a doctor may decide that lurasidone is the best medication to treat a child's condition.

You should know that your mental health may change in unexpected ways when you take lurasidone to treat depression or other mental illness even if you are an adult over 24 years of age. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own.

Your healthcare provider will want to see you often while you are taking lurasidone, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor.

No matter what your age, before you take an antidepressant, you, your family, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal. This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or mania or has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and personal and family medical history. You and your doctor will decide what type of treatment is right for you.

Lurasidone is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions) in adults and children 13 years of age and older. It is also used to treat depression in adults and children 10 years of age and older with bipolar disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods). Lurasidone is also used along with lithium (Lithobid) or valproate (Depacon) to treat depression in adults with bipolar disorder. Lurasidone is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substances in the brain.

Lurasidone comes as a tablet to take by mouth. It is usually taken with a meal (at least 350 calories) once a day. Take lurasidone at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take lurasidone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Lurasidone controls schizophrenia and depression in people with bipolar disorder but it does not cure these conditions. It may take several weeks or longer before you feel the full benefit of lurasidone. Continue to take lurasidone even if you feel well. Do not stop taking lurasidone without talking to your doctor.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking lurasidone,

  • tell your doctor and pharmacist if you are allergic to lurasidone, any other medications, or any of the ingredients in lurasidone tablets. Ask your pharmacist for a list of the ingredients.

  • tell your doctor if you are taking carbamazepine (Carbatrol, Epitol, Tegretol); clarithromycin (Biaxin, in Prevpac); ketoconazole; mibefradil; phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); ritonavir (Norvir); St. John's wort; or voriconazole (Vfend). Your doctor will probably tell you not to take lurasidone if you are taking either of these medications.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: antidepressants; antihistamines; atazanavir (Reyataz); bosentan (Tracleer); diltiazem (Cardizem, Cartia, Taztia, Tiazac, others); efavirenz (Sustiva, in Atripla); erythromycin (E.E.S., E-Mycin, Ery-Tab, others); etravirine (Intelence); fluconazole (Diflucan); indinavir (Crixivan); ipratropium (Atrovent, in Combivent, in Duoneb); itraconazole (Sporanox); medications to control anxiety, sedatives, sleeping pills, or tranquilizers; medications to control blood pressure; medications for glaucoma, inflammatory bowel disease, motion sickness, myasthenia gravis, Parkinson's disease, ulcers, or urinary problems; modafinil (Provigil); nafcillin; nefazodone; nelfinavir (Viracept); phenobarbital; pioglitazone (Actos, in Duetact, in Actoplus Met); rifabutin (Mycobutin); or verapamil (Calan, Verelan, others, in Tarka); Other medications may also interact with lurasidone, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you use or have ever used street drugs or have overused prescription medications and if you have or have ever had a stroke; a ministroke (TIA); chest pain, heart disease, or a heart attack; an irregular heartbeat; heart failure; Parkinson's disease (a disorder of the nervous system that causes difficulties with movement, muscle control, and balance); Alzheimer's disease (a brain disease that slowly destroys the memory and ability to think, learn, communicate and handle daily activities); seizures; dementia; breast cancer; trouble keeping your balance; any condition that makes it difficult for you to swallow; high or low blood pressure; high prolactin levels; a high level of fats (cholesterol and triglycerides) in your blood; a low number of white blood cells; kidney disease; liver disease; high blood sugar; or if you or anyone in your family has or has ever had diabetes. Tell your doctor if you have severe vomiting or diarrhea or signs of dehydration now, or if you develop these symptoms at any time during your treatment. Also tell your doctor if you have ever had to stop taking a medication for mental illness because of severe side effects.

  • tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, or if you plan to become pregnant or are breastfeeding. If you become pregnant while taking lurasidone, call your doctor. Lurasidone may cause problems in newborns following delivery if it is taken during the last months of pregnancy.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking lurasidone.

  • you should know that lurasidone may make you drowsy. Do not drive a car or operate hazardous machinery until you know how this medication affects you.

  • you should know that you may experience hyperglycemia (increases in your blood sugar) while you are taking this medication, even if you do not already have diabetes. If you have schizophrenia, you are more likely to develop diabetes than people who do not have schizophrenia, and taking lurasidone or similar medications may increase this risk. Tell your doctor immediately if you have any of the following symptoms while you are taking lurasidone: extreme thirst, frequent urination, extreme hunger, blurred vision, or weakness. It is very important to call your doctor as soon as you have any of these symptoms, because high blood sugar can cause a serious condition called ketoacidosis. Ketoacidosis may become life-threatening if it is not treated at an early stage. Symptoms of ketoacidosis include dry mouth, nausea and vomiting, shortness of breath, breath that smells fruity, and decreased consciousness.

  • you should know that lurasidone may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking lurasidone. To help avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

  • you should know that lurasidone may make it harder for your body to cool down when it gets very hot. Tell your doctor if you plan to exercise or be exposed to extreme heat.

  • you should know that lurasidone may cause an increase in weight. It is important to have your weight checked periodically while you are taking this medication.

Do not eat large amounts of grapefruit or drink grapefruit juice while taking this medication.

Take the missed dose with food (at least 350 calories) as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Lurasidone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • dizziness, feeling unsteady, or having trouble keeping your balance

    • anxiety

    • weakness

    • tiredness

    • restlessness

    • uncontrollable shaking of a part of the body

    • slow movements or shuffling walk

    • nausea

    • vomiting

    • appetite changes

    • increased saliva

    • breast enlargement or discharge

    • late or missed menstrual period

    • decreased sexual ability

  • Some side effects can be serious. If you experience any of these symptoms, or those listed in the IMPORTANT WARNINGS and SPECIAL PRECAUTIONS sections, call your doctor immediately:

    • seizures

    • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

    • hoarseness

    • difficulty swallowing or breathing

    • shortness of breath

    • abnormal heartbeat

    • sore throat, fever, cough, chills, and other signs of infection

    • fever, sweating, confusion, fast or irregular heartbeat, and severe muscle stiffness

    • unusual movements of your face or body that you cannot control

    • falling

  • Lurasidone may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to lurasidone.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Moxifloxacin.
Repaglinide Repaglinide The therapeutic efficacy of Repaglinide can be decreased when used in combination with Lurasidone.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection The therapeutic efficacy of Insulin glargine can be decreased when used in combination with Lurasidone.
Dolasetron Dolasetron The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Dolasetron.
Anagrelide Anagrelide The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Anagrelide.
Candesartan Candesartan Lurasidone may decrease the antihypertensive activities of Candesartan.
Cilostazol Cilostazol The risk or severity of QTc prolongation can be increased when Cilostazol is combined with Lurasidone.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Diphenoxylate is combined with Lurasidone.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The metabolism of Lurasidone can be decreased when combined with Erythromycin.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Lurasidone is combined with Guanfacine.
Methylergonovine Methylergonovine The risk or severity of hypertension can be increased when Methylergometrine is combined with Lurasidone.
Miglitol Miglitol The therapeutic efficacy of Miglitol can be decreased when used in combination with Lurasidone.
Naratriptan Naratriptan The risk or severity of adverse effects can be increased when Naratriptan is combined with Lurasidone.
Olsalazine Olsalazine The risk or severity of hypertension can be increased when Olsalazine is combined with Lurasidone.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Lurasidone.
Penbutolol Penbutolol The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Acebutolol.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Lurasidone.
Reserpine Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Lurasidone.
Rizatriptan Rizatriptan The risk or severity of adverse effects can be increased when Rizatriptan is combined with Lurasidone.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Sumatriptan is combined with Lurasidone.
Tacrolimus Tacrolimus The risk or severity of QTc prolongation can be increased when Tacrolimus is combined with Lurasidone.
Tizanidine Tizanidine The risk or severity of adverse effects can be increased when Tizanidine is combined with Lurasidone.
Zolmitriptan Zolmitriptan The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Lurasidone.
Famotidine Injection Famotidine Injection The risk or severity of QTc prolongation can be increased when Famotidine is combined with Lurasidone.
Fluconazole Injection Fluconazole Injection The metabolism of Lurasidone can be decreased when combined with Fluconazole.
Foscarnet Injection Foscarnet Injection The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Lurasidone.
Hydromorphone Injection Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Lurasidone.
Levofloxacin Injection Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Levofloxacin.
Meperidine Injection Meperidine Injection The risk or severity of adverse effects can be increased when Meperidine is combined with Lurasidone.
Metoclopramide Injection Metoclopramide Injection The risk or severity of adverse effects can be increased when Metoclopramide is combined with Lurasidone.
Metronidazole Injection Metronidazole Injection The risk or severity of QTc prolongation can be increased when Metronidazole is combined with Lurasidone.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Lurasidone.
Altretamine Altretamine The therapeutic efficacy of Lurasidone can be decreased when used in combination with Amphetamine.
Cyclosporine Cyclosporine The metabolism of Lurasidone can be decreased when combined with Cyclosporine.
Ondansetron Ondansetron The risk or severity of adverse effects can be increased when Ondansetron is combined with Lurasidone.
Granisetron Granisetron The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Granisetron.
Torsemide Torsemide Lurasidone may decrease the antihypertensive activities of Torasemide.
Olanzapine Olanzapine Olanzapine may increase the hypotensive activities of Lurasidone.
Alosetron Alosetron The risk or severity of adverse effects can be increased when Alosetron is combined with Lurasidone.
Dofetilide Dofetilide The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Dofetilide.
Entacapone Entacapone The therapeutic efficacy of Entacapone can be decreased when used in combination with Lurasidone.
Eprosartan Eprosartan Lurasidone may decrease the antihypertensive activities of Eprosartan.
Hydroxychloroquine Hydroxychloroquine The risk or severity of QTc prolongation can be increased when Hydroxychloroquine is combined with Lurasidone.
Meloxicam Meloxicam The risk or severity of hypertension can be increased when Meloxicam is combined with Lurasidone.
Oxcarbazepine Oxcarbazepine The risk or severity of adverse effects can be increased when Oxcarbazepine is combined with Lurasidone.
Telmisartan Telmisartan Lurasidone may decrease the antihypertensive activities of Telmisartan.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Zaleplon is combined with Lurasidone.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Desloratadine is combined with Lurasidone.
Linezolid Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Lurasidone.
Trimipramine Trimipramine Trimipramine may increase the hypotensive activities of Lurasidone.
Glycopyrrolate Glycopyrrolate Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Perindopril Perindopril Lurasidone may decrease the antihypertensive activities of Perindopril.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Lurasidone.
Dutasteride Dutasteride The risk or severity of hypertension can be increased when Dutasteride is combined with Lurasidone.
Epinephrine Injection Epinephrine Injection Epinephrine may increase the hypotensive activities of Lurasidone.
Eplerenone Eplerenone Lurasidone may decrease the antihypertensive activities of Eplerenone.
Escitalopram Escitalopram The risk or severity of serotonin syndrome can be increased when Escitalopram is combined with Lurasidone.
Olmesartan Olmesartan Lurasidone may decrease the antihypertensive activities of Olmesartan.
Zonisamide Zonisamide The risk or severity of adverse effects can be increased when Zonisamide is combined with Lurasidone.
Aripiprazole Aripiprazole Aripiprazole may increase the hypotensive activities of Lurasidone.
Atomoxetine Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Lurasidone.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Dexmethylphenidate is combined with Lurasidone.
Atazanavir Atazanavir The risk or severity of QTc prolongation can be increased when Atazanavir is combined with Lurasidone.
Almotriptan Almotriptan The risk or severity of adverse effects can be increased when Almotriptan is combined with Lurasidone.
Eletriptan Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Lurasidone.
Mefloquine Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Lurasidone.
Vardenafil Vardenafil The risk or severity of QTc prolongation can be increased when Vardenafil is combined with Lurasidone.
Alfuzosin Alfuzosin Alfuzosin may increase the hypotensive activities of Lurasidone.
Aprepitant Aprepitant The metabolism of Lurasidone can be decreased when combined with Aprepitant.
Memantine Memantine The therapeutic efficacy of Memantine can be decreased when used in combination with Lurasidone.
Tegaserod Tegaserod The risk or severity of serotonin syndrome can be increased when Tegaserod is combined with Lurasidone.
Tadalafil Tadalafil Lurasidone may decrease the antihypertensive activities of Tadalafil.
Frovatriptan Frovatriptan The risk or severity of adverse effects can be increased when Frovatriptan is combined with Lurasidone.
Gemifloxacin Gemifloxacin The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Gemifloxacin.
Apomorphine Injection Apomorphine Injection The therapeutic efficacy of Apomorphine can be decreased when used in combination with Lurasidone.
Protriptyline Protriptyline The risk or severity of adverse effects can be increased when Protriptyline is combined with Lurasidone.
Duloxetine Duloxetine The risk or severity of adverse effects can be increased when Lurasidone is combined with Duloxetine.
Trospium Trospium Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Bosentan Bosentan Lurasidone may decrease the antihypertensive activities of Bosentan.
Erlotinib Erlotinib The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Erlotinib.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Lurasidone is combined with Eszopiclone.
Insulin Aspart (rDNA Origin) Injection Insulin Aspart (rDNA Origin) Injection The therapeutic efficacy of Insulin aspart can be decreased when used in combination with Lurasidone.
Solifenacin Solifenacin Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Voriconazole Voriconazole The metabolism of Lurasidone can be decreased when combined with Voriconazole.
Dextroamphetamine Dextroamphetamine The therapeutic efficacy of Lurasidone can be decreased when used in combination with Amphetamine.
Pramlintide Injection Pramlintide Injection The therapeutic efficacy of Pramlintide can be decreased when used in combination with Lurasidone.
Sodium Oxybate Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Lurasidone.
Exenatide Injection Exenatide Injection The therapeutic efficacy of Exenatide can be decreased when used in combination with Lurasidone.
Ibandronate Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Lurasidone.
Isocarboxazid Isocarboxazid The risk or severity of adverse effects can be increased when Isocarboxazid is combined with Lurasidone.
Ramelteon Ramelteon The risk or severity of adverse effects can be increased when Ramelteon is combined with Lurasidone.
Darifenacin Darifenacin Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Darifenacin.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Fentanyl is combined with Lurasidone.
Pregabalin Pregabalin The therapeutic efficacy of Lurasidone can be increased when used in combination with Pregabalin.
Phenylephrine Phenylephrine The risk or severity of hypertension can be increased when Phenylephrine is combined with Lurasidone.
Felbamate Felbamate The risk or severity of adverse effects can be increased when Felbamate is combined with Lurasidone.
Insulin Detemir (rDNA Origin) Injection Insulin Detemir (rDNA Origin) Injection The therapeutic efficacy of Insulin detemir can be decreased when used in combination with Lurasidone.
Ranolazine Ranolazine The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Ranolazine.
Rasagiline Rasagiline The therapeutic efficacy of Rasagiline can be decreased when used in combination with Lurasidone.
Imatinib Imatinib The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Imatinib.
Sitagliptin Sitagliptin The therapeutic efficacy of Sitagliptin can be decreased when used in combination with Lurasidone.
Albuterol Albuterol The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Lurasidone.
Paliperidone Paliperidone Paliperidone may increase the hypotensive activities of Lurasidone.
Bortezomib Bortezomib The risk or severity of QTc prolongation can be increased when Bortezomib is combined with Lurasidone.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection The therapeutic efficacy of Insulin glulisine can be decreased when used in combination with Lurasidone.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Oxaliplatin.
Posaconazole Posaconazole The risk or severity of QTc prolongation can be increased when Posaconazole is combined with Lurasidone.
Primaquine Primaquine The metabolism of Lurasidone can be decreased when combined with Primaquine.
Aliskiren Aliskiren Lurasidone may decrease the antihypertensive activities of Aliskiren.
Bismuth Subsalicylate Bismuth Subsalicylate Bismuth subsalicylate may increase the neurotoxic activities of Lurasidone.
Dimenhydrinate Dimenhydrinate The risk or severity of adverse effects can be increased when Dimenhydrinate is combined with Lurasidone.
Lisdexamfetamine Lisdexamfetamine The therapeutic efficacy of Lurasidone can be decreased when used in combination with Lisdexamfetamine.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Lurasidone.
Vorinostat Vorinostat The risk or severity of QTc prolongation can be increased when Vorinostat is combined with Lurasidone.
Sorafenib Sorafenib The risk or severity of QTc prolongation can be increased when Sorafenib is combined with Lurasidone.
Sunitinib Sunitinib The therapeutic efficacy of Sunitinib can be decreased when used in combination with Lurasidone.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Lurasidone.
Lapatinib Lapatinib The risk or severity of QTc prolongation can be increased when Lapatinib is combined with Lurasidone.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Levocetirizine is combined with Lurasidone.
Dasatinib Dasatinib The risk or severity of QTc prolongation can be increased when Dasatinib is combined with Lurasidone.
Nilotinib Nilotinib The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Nilotinib.
Toremifene Toremifene The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Toremifene.
Desmopressin Desmopressin The risk or severity of hypertension can be increased when Desmopressin is combined with Lurasidone.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Lurasidone.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Lurasidone.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Arsenic trioxide.
Desvenlafaxine Desvenlafaxine The metabolism of Lurasidone can be decreased when combined with Desvenlafaxine.
Nebivolol Nebivolol Lurasidone may decrease the antihypertensive activities of Nebivolol.
Flecainide Flecainide The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Flecainide.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Lurasidone.
Silodosin Silodosin Silodosin may increase the hypotensive activities of Lurasidone.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Midazolam is combined with Lurasidone.
Naltrexone Injection Naltrexone Injection The risk or severity of serotonin syndrome can be increased when Naltrexone is combined with Lurasidone.
Milnacipran Milnacipran The metabolism of Lurasidone can be decreased when combined with Milnacipran.
Fesoterodine Fesoterodine Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Degarelix Injection Degarelix Injection The risk or severity of QTc prolongation can be increased when Degarelix is combined with Lurasidone.
Betaxolol Betaxolol The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Betaxolol.
Iloperidone Iloperidone Iloperidone may increase the hypotensive activities of Lurasidone.
Lacosamide Lacosamide The risk or severity of adverse effects can be increased when Lacosamide is combined with Lurasidone.
Dronedarone Dronedarone The metabolism of Lurasidone can be decreased when combined with Dronedarone.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Lurasidone.
Palonosetron Injection Palonosetron Injection The risk or severity of adverse effects can be increased when Palonosetron is combined with Lurasidone.
Saxagliptin Saxagliptin The therapeutic efficacy of Saxagliptin can be decreased when used in combination with Lurasidone.
Telavancin Injection Telavancin Injection The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Telavancin.
Romidepsin Injection Romidepsin Injection The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Romidepsin.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Lurasidone.
Pazopanib Pazopanib The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Pazopanib.
Asenapine Asenapine Asenapine may increase the hypotensive activities of Lurasidone.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Vigabatrin is combined with Lurasidone.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Oxymorphone is combined with Lurasidone.
Liraglutide Injection Liraglutide Injection The therapeutic efficacy of Liraglutide can be decreased when used in combination with Lurasidone.
Eribulin Injection Eribulin Injection The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Eribulin.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Lurasidone.
Vilazodone Vilazodone The risk or severity of adverse effects can be increased when Vilazodone is combined with Lurasidone.
Terbutaline Injection Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Lurasidone.
Linagliptin Linagliptin The metabolism of Lurasidone can be decreased when combined with Linagliptin.
Rilpivirine Rilpivirine The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Rilpivirine.
Cyclophosphamide Injection Cyclophosphamide Injection Cyclophosphamide may increase the neurotoxic activities of Lurasidone.
Triptorelin Injection Triptorelin Injection The risk or severity of QTc prolongation can be increased when Triptorelin is combined with Lurasidone.
Vandetanib Vandetanib The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Vandetanib.
Clobazam Clobazam The risk or severity of adverse effects can be increased when Clobazam is combined with Lurasidone.
Vemurafenib Vemurafenib The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Lurasidone.
Crizotinib Crizotinib The metabolism of Lurasidone can be decreased when combined with Crizotinib.
Cabergoline Cabergoline The risk or severity of adverse effects can be increased when Cabergoline is combined with Lurasidone.
Ambrisentan Ambrisentan Lurasidone may decrease the antihypertensive activities of Ambrisentan.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Tiagabine is combined with Lurasidone.
Mirabegron Mirabegron The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Mirabegron.
Lorcaserin Lorcaserin The therapeutic efficacy of Mecasermin can be decreased when used in combination with Lurasidone.
Bedaquiline Bedaquiline The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Bedaquiline.
Alogliptin Alogliptin The therapeutic efficacy of Alogliptin can be decreased when used in combination with Lurasidone.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Lurasidone is combined with Pomalidomide.
Canagliflozin Canagliflozin The therapeutic efficacy of Canagliflozin can be decreased when used in combination with Lurasidone.
Dabrafenib Dabrafenib The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Dabrafenib.
Levomilnacipran Levomilnacipran The risk or severity of adverse effects can be increased when Lurasidone is combined with Levomilnacipran.
Vortioxetine Vortioxetine The risk or severity of adverse effects can be increased when Lurasidone is combined with Vortioxetine.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Lurasidone.
Ketorolac Injection Ketorolac Injection The risk or severity of hypertension can be increased when Ketorolac is combined with Lurasidone.
Simeprevir Simeprevir The metabolism of Lurasidone can be decreased when combined with Simeprevir.
Dapagliflozin Dapagliflozin The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Lurasidone.
Droxidopa Droxidopa Lurasidone may decrease the hypertensive activities of Droxidopa.
Ceritinib Ceritinib The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Ceritinib.
Albiglutide Injection Albiglutide Injection The therapeutic efficacy of Albiglutide can be decreased when used in combination with Lurasidone.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Lurasidone is combined with Eslicarbazepine.
Empagliflozin Empagliflozin The therapeutic efficacy of Empagliflozin can be decreased when used in combination with Lurasidone.
Hydrocodone Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Lurasidone.
Suvorexant Suvorexant Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Dulaglutide Injection Dulaglutide Injection The therapeutic efficacy of Dulaglutide can be decreased when used in combination with Lurasidone.
Methamphetamine Methamphetamine The therapeutic efficacy of Lurasidone can be decreased when used in combination with Metamfetamine.
Tasimelteon Tasimelteon The risk or severity of adverse effects can be increased when Lurasidone is combined with Tasimelteon.
Riociguat Riociguat Lurasidone may decrease the antihypertensive activities of Riociguat.
Risperidone Injection Risperidone Injection Risperidone may increase the hypotensive activities of Lurasidone.
Insulin Human Inhalation Insulin Human Inhalation The therapeutic efficacy of Insulin human can be decreased when used in combination with Lurasidone.
Lenvatinib Lenvatinib The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Lenvatinib.
Panobinostat Panobinostat The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Panobinostat.
Haloperidol Injection Haloperidol Injection The metabolism of Lurasidone can be decreased when combined with Haloperidol.
Ivabradine Ivabradine The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Ivabradine.
Isavuconazonium Injection Isavuconazonium Injection The metabolism of Lurasidone can be decreased when combined with Isavuconazonium.
Macitentan Macitentan Lurasidone may decrease the antihypertensive activities of Macitentan.
Flibanserin Flibanserin The risk or severity of adverse effects can be increased when Flibanserin is combined with Lurasidone.
Brexpiprazole Brexpiprazole Brexpiprazole may increase the hypotensive activities of Lurasidone.
Ziprasidone Injection Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Ziprasidone is combined with Lurasidone.
Cariprazine Cariprazine The risk or severity of adverse effects can be increased when Cariprazine is combined with Lurasidone.
Eluxadoline Eluxadoline The risk or severity of serotonin syndrome can be increased when Lurasidone is combined with Eluxadoline.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection The therapeutic efficacy of Insulin degludec can be decreased when used in combination with Lurasidone.
Brivaracetam Injection Brivaracetam Injection The risk or severity of adverse effects can be increased when Brivaracetam is combined with Lurasidone.
Venetoclax Venetoclax The metabolism of Lurasidone can be decreased when combined with Venetoclax.
Midodrine Midodrine The risk or severity of hypertension can be increased when Midodrine is combined with Lurasidone.
Selexipag Selexipag Lurasidone may decrease the antihypertensive activities of Selexipag.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Pimavanserin is combined with Lurasidone.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Lurasidone.
Furosemide Injection Furosemide Injection Lurasidone may decrease the antihypertensive activities of Furosemide.
Lixisenatide Injection Lixisenatide Injection The therapeutic efficacy of Lixisenatide can be decreased when used in combination with Lurasidone.
Ribociclib Ribociclib The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Ribociclib.
Doxepin (Insomnia) Doxepin (Insomnia) Doxepin may increase the hypotensive activities of Lurasidone.
Deutetrabenazine Deutetrabenazine The risk or severity of adverse effects can be increased when Lurasidone is combined with Deutetrabenazine.
Safinamide Safinamide The therapeutic efficacy of Safinamide can be decreased when used in combination with Lurasidone.
Delafloxacin Delafloxacin The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Delafloxacin.
Semaglutide Injection Semaglutide Injection The therapeutic efficacy of Semaglutide can be decreased when used in combination with Lurasidone.
Tetrabenazine Tetrabenazine The risk or severity of adverse effects can be increased when Lurasidone is combined with Tetrabenazine.
Ertugliflozin Ertugliflozin The therapeutic efficacy of Ertugliflozin can be decreased when used in combination with Lurasidone.
Buprenorphine Injection Buprenorphine Injection Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Lofexidine Lofexidine The therapeutic efficacy of Lurasidone can be increased when used in combination with Lofexidine.
Eliglustat Eliglustat The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Eliglustat.
Encorafenib Encorafenib The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Encorafenib.
Ivosidenib Ivosidenib The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Ivosidenib.
Cannabidiol Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Lurasidone.
Stiripentol Stiripentol The risk or severity of adverse effects can be increased when Lurasidone is combined with Stiripentol.
Gilteritinib Gilteritinib The therapeutic efficacy of Lurasidone can be decreased when used in combination with Gilteritinib.
Glasdegib Glasdegib The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Glasdegib.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection Paclitaxel may increase the neurotoxic activities of Lurasidone.
Siponimod Siponimod The risk or severity of hypertension can be increased when Lurasidone is combined with Siponimod.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Lurasidone is combined with Brexanolone.
Solriamfetol Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Lurasidone.
Triclabendazole Triclabendazole The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Triclabendazole.
Entrectinib Entrectinib The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Entrectinib.
Pitolisant Pitolisant The serum concentration of Lurasidone can be decreased when it is combined with Pitolisant.
Lefamulin Lefamulin Lefamulin may increase the QTc-prolonging activities of Lurasidone.
Phenytoin Injection Phenytoin Injection The risk or severity of adverse effects can be increased when Phenytoin is combined with Lurasidone.
Fosphenytoin Injection Fosphenytoin Injection The risk or severity of adverse effects can be increased when Fosphenytoin is combined with Lurasidone.
Lumateperone Lumateperone The risk or severity of adverse effects can be increased when Lumateperone is combined with Lurasidone.
Lasmiditan Lasmiditan The risk or severity of serotonin syndrome can be increased when Lurasidone is combined with Lasmiditan.
Cenobamate Cenobamate The serum concentration of Lurasidone can be decreased when it is combined with Cenobamate.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Lurasidone.
Selpercatinib Selpercatinib The risk or severity of hypertension can be increased when Lurasidone is combined with Selpercatinib.
Lemborexant Lemborexant The risk or severity of adverse effects can be increased when Lurasidone is combined with Lemborexant.
Fenfluramine Fenfluramine The risk or severity of serotonin syndrome can be increased when Fenfluramine is combined with Lurasidone.
Fostemsavir Fostemsavir The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Fostemsavir.
Octreotide Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Lurasidone.
Opicapone Opicapone The therapeutic efficacy of Opicapone can be decreased when used in combination with Lurasidone.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Lurasidone can be decreased when it is combined with Satralizumab.
Naxitamab-gqgk Injection Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Lurasidone is combined with Naxitamab.
Relugolix Relugolix The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Relugolix.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Lurasidone is combined with Viloxazine.
Fenoprofen Fenoprofen The risk or severity of hypertension can be increased when Fenoprofen is combined with Lurasidone.
Indomethacin Indomethacin The risk or severity of hypertension can be increased when Indomethacin is combined with Lurasidone.
Mefenamic Acid Mefenamic Acid The risk or severity of hypertension can be increased when Mefenamic acid is combined with Lurasidone.
Naproxen Naproxen The risk or severity of hypertension can be increased when Naproxen is combined with Lurasidone.
Tolmetin Tolmetin The risk or severity of hypertension can be increased when Tolmetin is combined with Lurasidone.
Sulindac Sulindac The risk or severity of hypertension can be increased when Sulindac is combined with Lurasidone.
Trazodone Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Lurasidone.
Phenobarbital Phenobarbital The risk or severity of adverse effects can be increased when Phenobarbital is combined with Lurasidone.
Metaxalone Metaxalone The risk or severity of adverse effects can be increased when Metaxalone is combined with Lurasidone.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Levorphanol is combined with Lurasidone.
Primidone Primidone The risk or severity of adverse effects can be increased when Primidone is combined with Lurasidone.
Methsuximide Methsuximide The risk or severity of adverse effects can be increased when Methsuximide is combined with Lurasidone.
Diethylpropion Diethylpropion The therapeutic efficacy of Lurasidone can be decreased when used in combination with Diethylpropion.
Chlorpromazine Chlorpromazine Chlorpromazine may increase the hypotensive activities of Lurasidone.
Diazepam Diazepam The risk or severity of adverse effects can be increased when Diazepam is combined with Lurasidone.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Oxazepam is combined with Lurasidone.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Flurazepam is combined with Lurasidone.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Clorazepic acid is combined with Lurasidone.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Lurasidone.
Phenoxybenzamine Phenoxybenzamine Phenoxybenzamine may increase the hypotensive activities of Lurasidone.
Amantadine Amantadine The therapeutic efficacy of Amantadine can be decreased when used in combination with Lurasidone.
Codeine Codeine The risk or severity of adverse effects can be increased when Codeine is combined with Lurasidone.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Lurasidone.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Lurasidone.
Bromocriptine Bromocriptine Bromocriptine may increase the hypotensive activities of Lurasidone.
Metaproterenol Metaproterenol The risk or severity of hypertension can be increased when Orciprenaline is combined with Lurasidone.
Tranylcypromine Tranylcypromine The risk or severity of adverse effects can be increased when Tranylcypromine is combined with Lurasidone.
Phenelzine Phenelzine The risk or severity of adverse effects can be increased when Phenelzine is combined with Lurasidone.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Lurasidone.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of adverse effects can be increased when Ergoloid mesylate is combined with Lurasidone.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Lurasidone.
Prochlorperazine Prochlorperazine The risk or severity of adverse effects can be increased when Prochlorperazine is combined with Lurasidone.
Thioridazine Thioridazine Thioridazine may increase the hypotensive activities of Lurasidone.
Trifluoperazine Trifluoperazine Trifluoperazine may increase the hypotensive activities of Lurasidone.
Sulfadiazine Sulfadiazine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Lurasidone.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Lurasidone.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Lurasidone.
Oxybutynin Oxybutynin Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin.
Benztropine Benztropine The risk or severity of adverse effects can be increased when Lurasidone is combined with Benzatropine.
Maprotiline Maprotiline The risk or severity of adverse effects can be increased when Maprotiline is combined with Lurasidone.
Ibuprofen Ibuprofen The risk or severity of hypertension can be increased when Ibuprofen is combined with Lurasidone.
Trihexyphenidyl Trihexyphenidyl The therapeutic efficacy of Trihexyphenidyl can be decreased when used in combination with Lurasidone.
Orphenadrine Orphenadrine Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The risk or severity of adverse effects can be increased when Perphenazine is combined with Lurasidone.
Fluphenazine Fluphenazine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Lurasidone.
Phentermine Phentermine The therapeutic efficacy of Lurasidone can be decreased when used in combination with Phentermine.
Methylphenidate Methylphenidate The risk or severity of adverse effects can be increased when Lurasidone is combined with Methylphenidate.
Amoxapine Amoxapine Amoxapine may increase the hypotensive activities of Lurasidone.
Sulfasalazine Sulfasalazine The risk or severity of hypertension can be increased when Sulfasalazine is combined with Lurasidone.
Carbamazepine Carbamazepine The risk or severity of adverse effects can be increased when Carbamazepine is combined with Lurasidone.
Molindone Molindone The risk or severity of adverse effects can be increased when Molindone is combined with Lurasidone.
Methyldopa Methyldopa Lurasidone may decrease the antihypertensive activities of Methyldopa.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Lurasidone.
Prazosin Prazosin Prazosin may increase the hypotensive activities of Lurasidone.
Hydralazine Hydralazine Lurasidone may decrease the antihypertensive activities of Hydralazine.
Warfarin Warfarin The risk or severity of adverse effects can be increased when Lurasidone is combined with Warfarin.
Clonazepam Clonazepam The risk or severity of adverse effects can be increased when Clonazepam is combined with Lurasidone.
Loperamide Loperamide The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Loperamide.
Promethazine Promethazine The risk or severity of adverse effects can be increased when Promethazine is combined with Lurasidone.
Meclofenamate Meclofenamate The risk or severity of hypertension can be increased when Meclofenamic acid is combined with Lurasidone.
Digoxin Digoxin The risk or severity of QTc prolongation can be increased when Digoxin is combined with Lurasidone.
Loxapine Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Lurasidone.
Chloroquine Chloroquine The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Chloroquine.
Quinine Quinine The risk or severity of adverse effects can be increased when Quinine is combined with Lurasidone.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Ethosuximide is combined with Lurasidone.
Chlorothiazide Chlorothiazide Lurasidone may decrease the antihypertensive activities of Chlorothiazide.
Chlorthalidone Chlorthalidone Lurasidone may decrease the antihypertensive activities of Chlorthalidone.
Metolazone Metolazone Lurasidone may decrease the antihypertensive activities of Metolazone.
Clindamycin Injection Clindamycin Injection Clindamycin may increase the neurotoxic activities of Lurasidone.
Secobarbital Secobarbital The risk or severity of adverse effects can be increased when Secobarbital is combined with Lurasidone.
Desipramine Desipramine Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Desipramine.
Amitriptyline Amitriptyline Amitriptyline may increase the hypotensive activities of Lurasidone.
Imipramine Imipramine Imipramine may increase the hypotensive activities of Lurasidone.
Quinidine Quinidine Quinidine may increase the hypotensive activities of Lurasidone.
Procainamide Procainamide The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Procainamide.
Isoniazid Isoniazid The metabolism of Lurasidone can be decreased when combined with Isoniazid.
Disopyramide Disopyramide The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Disopyramide.
Valproic Acid Valproic Acid The risk or severity of adverse effects can be increased when Valproic acid is combined with Lurasidone.
Tamoxifen Tamoxifen The risk or severity of QTc prolongation can be increased when Tamoxifen is combined with Lurasidone.
Butabarbital Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Lurasidone.
Chlorpropamide Chlorpropamide The therapeutic efficacy of Chlorpropamide can be decreased when used in combination with Lurasidone.
Tolbutamide Tolbutamide The therapeutic efficacy of Tolbutamide can be decreased when used in combination with Lurasidone.
Tolazamide Tolazamide The therapeutic efficacy of Tolazamide can be decreased when used in combination with Lurasidone.
Dextromethorphan Dextromethorphan The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Lurasidone.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Cyclobenzaprine is combined with Lurasidone.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Lurasidone.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Lurasidone.
Cyproheptadine Cyproheptadine Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine.
Clemastine Clemastine The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Clemastine.
Chlorpheniramine Chlorpheniramine The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Lurasidone.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Meclizine is combined with Lurasidone.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Hydrochlorothiazide is combined with Lurasidone.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Dantrolene is combined with Lurasidone.
Chlorzoxazone Chlorzoxazone The risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Lurasidone.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Lurasidone.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Methocarbamol is combined with Lurasidone.
Danazol Danazol The metabolism of Lurasidone can be decreased when combined with Danazol.
Disulfiram Disulfiram The risk or severity of QTc prolongation can be increased when Disulfiram is combined with Lurasidone.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Propranolol.
Minoxidil Minoxidil Lurasidone may decrease the antihypertensive activities of Minoxidil.
Pseudoephedrine Pseudoephedrine The therapeutic efficacy of Lurasidone can be decreased when used in combination with Pseudoephedrine.
Nortriptyline Nortriptyline Nortriptyline may increase the hypotensive activities of Lurasidone.
Nadolol Nadolol Lurasidone may decrease the antihypertensive activities of Nadolol.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Lurasidone.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Nalbuphine is combined with Lurasidone.
Oxytocin Injection Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Lurasidone.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Lurasidone.
Flavoxate Flavoxate Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Papaverine Papaverine The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Papaverine.
Fluorouracil Injection Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Fluorouracil.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Acetazolamide is combined with Lurasidone.
Ketoconazole Ketoconazole The risk or severity of QTc prolongation can be increased when Ketoconazole is combined with Lurasidone.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Lurasidone is combined with Pyrantel.
Vincristine Injection Vincristine Injection Vincristine may increase the neurotoxic activities of Lurasidone.
Captopril Captopril Lurasidone may decrease the antihypertensive activities of Captopril.
Isoxsuprine Isoxsuprine The risk or severity of hypertension can be increased when Lurasidone is combined with Isoxsuprine.
Metoprolol Metoprolol Lurasidone may decrease the antihypertensive activities of Metoprolol.
Hydroxyzine Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Lurasidone.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Thiothixene is combined with Lurasidone.
Aspirin Aspirin The risk or severity of hypertension can be increased when Acetylsalicylic acid is combined with Lurasidone.
Salsalate Salsalate The risk or severity of hypertension can be increased when Salsalate is combined with Lurasidone.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Lurasidone.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Lurasidone.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Triazolam is combined with Lurasidone.
Dicyclomine Dicyclomine Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine Hyoscyamine Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline Propantheline Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Diltiazem Diltiazem The metabolism of Lurasidone can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Nifedipine.
Timolol Timolol The risk or severity of QTc prolongation can be increased when Timolol is combined with Lurasidone.
Verapamil Verapamil The metabolism of Lurasidone can be decreased when combined with Verapamil.
Atenolol Atenolol Lurasidone may decrease the antihypertensive activities of Atenolol.
Pindolol Pindolol The risk or severity of adverse effects can be increased when Pindolol is combined with Lurasidone.
Diflunisal Diflunisal The risk or severity of hypertension can be increased when Diflunisal is combined with Lurasidone.
Piroxicam Piroxicam The risk or severity of hypertension can be increased when Piroxicam is combined with Lurasidone.
Glyburide Glyburide The therapeutic efficacy of Glyburide can be decreased when used in combination with Lurasidone.
Glipizide Glipizide The therapeutic efficacy of Glipizide can be decreased when used in combination with Lurasidone.
Indapamide Indapamide The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Indapamide.
Pentamidine Injection Pentamidine Injection The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Pentamidine.
Labetalol Labetalol Labetalol may increase the hypotensive activities of Lurasidone.
Leuprolide Injection Leuprolide Injection The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Leuprolide.
Guanabenz Guanabenz The risk or severity of hypertension can be increased when Guanabenz is combined with Lurasidone.
Ketoprofen Ketoprofen The risk or severity of hypertension can be increased when Ketoprofen is combined with Lurasidone.
Pimozide Pimozide The risk or severity of adverse effects can be increased when Pimozide is combined with Lurasidone.
Enalapril Enalapril Lurasidone may decrease the antihypertensive activities of Enalapril.
Flurbiprofen Flurbiprofen The risk or severity of hypertension can be increased when Flurbiprofen is combined with Lurasidone.
Amiodarone Amiodarone The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Amiodarone.
Buspirone Buspirone The risk or severity of serotonin syndrome can be increased when Buspirone is combined with Lurasidone.
Lovastatin Lovastatin The metabolism of Lurasidone can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The metabolism of Lurasidone can be decreased when combined with Ciprofloxacin.
Mesalamine Mesalamine The risk or severity of hypertension can be increased when Mesalazine is combined with Lurasidone.
Diclofenac Diclofenac The risk or severity of hypertension can be increased when Diclofenac is combined with Lurasidone.
Fluoxetine Fluoxetine The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Lurasidone.
Nimodipine Nimodipine The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Nimodipine.
Clozapine Clozapine The metabolism of Lurasidone can be decreased when combined with Clozapine.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Estazolam is combined with Lurasidone.
Ofloxacin Ofloxacin The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Ofloxacin.
Didanosine Didanosine Didanosine may increase the neurotoxic activities of Lurasidone.
Clarithromycin Clarithromycin The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Clarithromycin.
Benazepril Benazepril Lurasidone may decrease the antihypertensive activities of Benazepril.
Etodolac Etodolac The risk or severity of hypertension can be increased when Etodolac is combined with Lurasidone.
Felodipine Felodipine The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Felodipine.
Fosinopril Fosinopril Lurasidone may decrease the antihypertensive activities of Fosinopril.
Nabumetone Nabumetone The risk or severity of hypertension can be increased when Nabumetone is combined with Lurasidone.
Quinapril Quinapril Lurasidone may decrease the antihypertensive activities of Quinapril.
Ramipril Ramipril Lurasidone may decrease the antihypertensive activities of Ramipril.
Amlodipine Amlodipine Lurasidone may decrease the antihypertensive activities of Amlodipine.
Teniposide Injection Teniposide Injection Teniposide may increase the neurotoxic activities of Lurasidone.
Itraconazole Itraconazole The risk or severity of QTc prolongation can be increased when Itraconazole is combined with Lurasidone.
Lisinopril Lisinopril Lurasidone may decrease the antihypertensive activities of Lisinopril.
Oxaprozin Oxaprozin The risk or severity of hypertension can be increased when Oxaprozin is combined with Lurasidone.
Sotalol Sotalol The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Sotalol.
Bisoprolol Bisoprolol Lurasidone may decrease the antihypertensive activities of Bisoprolol.
Zolpidem Zolpidem Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin Doxazosin Doxazosin may increase the hypotensive activities of Lurasidone.
Terazosin Terazosin Terazosin may increase the hypotensive activities of Lurasidone.
Isradipine Isradipine The metabolism of Lurasidone can be decreased when combined with Isradipine.
Cisapride Cisapride The risk or severity of adverse effects can be increased when Cisapride is combined with Lurasidone.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Gabapentin is combined with Lurasidone.
Venlafaxine Venlafaxine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Lurasidone.
Stavudine Stavudine Stavudine may increase the neurotoxic activities of Lurasidone.
Fluvoxamine Fluvoxamine The metabolism of Lurasidone can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone Nefazodone may increase the hypotensive activities of Lurasidone.
Lamotrigine Lamotrigine The risk or severity of adverse effects can be increased when Lamotrigine is combined with Lurasidone.
Losartan Losartan The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Losartan.
Tramadol Tramadol The risk or severity of serotonin syndrome can be increased when Lurasidone is combined with Tramadol.
Vinorelbine Injection Vinorelbine Injection Vinorelbine may increase the neurotoxic activities of Lurasidone.
Moexipril Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Lurasidone.
Nicardipine Nicardipine The metabolism of Lurasidone can be decreased when combined with Nicardipine.
Bupropion Bupropion The risk or severity of adverse effects can be increased when Bupropion is combined with Lurasidone.
Saquinavir Saquinavir The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Saquinavir.
Metformin Metformin The therapeutic efficacy of Metformin can be decreased when used in combination with Lurasidone.
Nisoldipine Nisoldipine Lurasidone may decrease the antihypertensive activities of Nisoldipine.
Riluzole Riluzole The risk or severity of adverse effects can be increased when Riluzole is combined with Lurasidone.
Acarbose Acarbose The therapeutic efficacy of Acarbose can be decreased when used in combination with Lurasidone.
Glimepiride Glimepiride The therapeutic efficacy of Glimepiride can be decreased when used in combination with Lurasidone.
Ritonavir Ritonavir The serum concentration of Lurasidone can be increased when it is combined with Ritonavir.
Clomipramine Clomipramine The risk or severity of adverse effects can be increased when Clomipramine is combined with Lurasidone.
Mirtazapine Mirtazapine Lurasidone may increase the serotonergic activities of Mirtazapine.
Trandolapril Trandolapril Lurasidone may decrease the antihypertensive activities of Trandolapril.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Lurasidone.
Valsartan Valsartan Lurasidone may decrease the antihypertensive activities of Valsartan.
Insulin Lispro Injection Insulin Lispro Injection The therapeutic efficacy of Insulin lispro can be decreased when used in combination with Lurasidone.
Pramipexole Pramipexole The therapeutic efficacy of Pramipexole can be decreased when used in combination with Lurasidone.
Donepezil Donepezil The risk or severity of adverse effects can be increased when Donepezil is combined with Lurasidone.
Nelfinavir Nelfinavir The risk or severity of QTc prolongation can be increased when Nelfinavir is combined with Lurasidone.
Azithromycin Azithromycin The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Azithromycin.
Carvedilol Carvedilol Carvedilol may increase the hypotensive activities of Lurasidone.
Selegiline Selegiline The risk or severity of adverse effects can be increased when Selegiline is combined with Lurasidone.
Sertraline Sertraline The risk or severity of adverse effects can be increased when Lurasidone is combined with Sertraline.
Propafenone Propafenone The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Propafenone.
Irbesartan Irbesartan Lurasidone may decrease the antihypertensive activities of Irbesartan.
Tamsulosin Tamsulosin Tamsulosin may increase the hypotensive activities of Lurasidone.
Ropinirole Ropinirole The therapeutic efficacy of Ropinirole can be decreased when used in combination with Lurasidone.
Finasteride Finasteride The risk or severity of hypertension can be increased when Finasteride is combined with Lurasidone.
Quetiapine Quetiapine Quetiapine may increase the hypotensive activities of Lurasidone.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Lurasidone.
Paroxetine Paroxetine The risk or severity of adverse effects can be increased when Lurasidone is combined with Paroxetine.
Tolcapone Tolcapone The therapeutic efficacy of Tolcapone can be decreased when used in combination with Lurasidone.
Citalopram Citalopram The risk or severity of adverse effects can be increased when Lurasidone is combined with Citalopram.
Efavirenz Efavirenz The risk or severity of adverse effects can be increased when Efavirenz is combined with Lurasidone.
Pioglitazone Pioglitazone The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Lurasidone.
Celecoxib Celecoxib The risk or severity of hypertension can be increased when Celecoxib is combined with Lurasidone.
Rosiglitazone Rosiglitazone The therapeutic efficacy of Rosiglitazone can be decreased when used in combination with Lurasidone.
Tolterodine Tolterodine Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
Thalidomide Thalidomide Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Balsalazide Balsalazide The risk or severity of hypertension can be increased when Balsalazide is combined with Lurasidone.
Nateglinide Nateglinide The therapeutic efficacy of Nateglinide can be decreased when used in combination with Lurasidone.
Galantamine Galantamine The risk or severity of QTc prolongation can be increased when Galantamine is combined with Lurasidone.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Levetiracetam is combined with Lurasidone.

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