Metoprolol drug information

Why is this medication prescribed?
How should this medicine be used?
Other uses for this medicine
What special precautions should I follow?
What special dietary instructions should I follow?
What should I do if I forget a dose?
What side effects can this medication cause?
What should I know about STORAGE and DISPOSAL of this medication?
What should I do in case of OVERDOSE?
What OTHER INFORMATION should I know?
Brand names of combination products
Drug interactions

IMPORTANT WARNING

Do not stop taking metoprolol without talking to your doctor. Suddenly stopping metoprolol may cause chest pain or heart attack. Your doctor will probably decrease your dose gradually.

Why is this medication prescribed?

Metoprolol is used alone or in combination with other medications to treat high blood pressure. It also is used to prevent angina (chest pain) and to improve survival after a heart attack. Metoprolol also is used in combination with other medications to treat heart failure. Metoprolol is in a class of medications called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.

High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

How should this medicine be used?

Metoprolol comes as a tablet and an extended-release (long-acting) tablet to take by mouth. The regular tablet is usually taken once or twice a day with meals or immediately after meals. The extended-release tablet is usually taken once a day. To help you remember to take metoprolol, take it around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take metoprolol exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

The extended-release tablet may be split. Swallow the whole or half tablets whole; do not chew or crush them.

Your doctor may start you on a low dose of metoprolol and gradually increase your dose.

Metoprolol controls high blood pressure and angina but does not cure them. Metoprolol extended-release tablets control heart failure but does not cure it. It may take a few weeks before you feel the full benefit of metoprolol. Continue to take metoprolol even if you feel well.

Other uses for this medicine

Metoprolol is also used sometimes to prevent migraine headaches and to treat irregular heartbeat and movement disorders caused by medications for mental illness. Talk to your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking metoprolol,

tell your doctor and pharmacist if you are allergic to metoprolol, acebutolol (Sectral), atenolol (Tenormin, in Tenoretic), betaxolol, bisoprolol (Zebeta, in Ziac), carvedilol (Coreg, Coreg CR), esmolol (Brevibloc), labetalol, nadolol (Corgard, in Corzide), pindolol, propranolol (Inderal, Inderal LA, Innopran XL, in Inderide), sotalol (Betapace, Betapace AF, Sorine), timolol, any other medications, or any of the ingredients in metoprolol tablets. Ask your pharmacist for a list of the ingredients.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: bupropion (Aplenzin, Forfivo, Wellbutrin, Zyban), cimetidine, clonidine (Catapres), diphenhydramine (Benadryl), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), hydroxychloroquine, paroxetine (Brisdelle, Paxil, Pexeva), propafenone (Rythmol), quinidine, ranitidine (Zantac), reserpine, ritonavir (Norvir, in Kaletra), terbinafine (Lamisil), and thioridazine. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

tell your doctor if you have a slow heart rate, heart failure, problems with blood circulation, or pheochromocytoma (a tumor that develops on a gland near the kidneys and may cause high blood pressure and fast heartbeat). Your doctor may tell you not to take metoprolol.

tell your doctor if you have or have ever had asthma or other lung diseases; heart or liver disease; diabetes; severe allergies; or hyperthyroidism (an overactive thyroid gland).

tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking metoprolol, call your doctor.

if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking metoprolol.

you should know that metoprolol may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.

remember that alcohol can add to the drowsiness caused by this medication.

you should know that if you have allergic reactions to different substances, your reactions may be worse while you are using metoprolol, and your allergic reactions may not respond to the usual doses of injectable epinephrine.

What special dietary instructions should I follow?

If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Metoprolol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- dizziness or lightheadedness
- tiredness
- depression
- nausea
- dry mouth
- stomach pain
- vomiting
- gas or bloating
- heartburn
- constipation
- rash or itching
- cold hands and feet
- runny nose

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
- shortness of breath
- wheezing
- swelling of the hands, feet, ankles, or lower legs
- weight gain
- fainting
- rapid, pounding, or irregular heartbeat
Metoprolol may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about STORAGE and DISPOSAL of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

What should I do in case of OVERDOSE?

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

dizziness
fainting
difficulty breathing or swallowing
swelling of the hands, feet, ankles, or lower legs

What OTHER INFORMATION should I know?

Keep all appointments with your doctor. Your blood pressure should be checked regularly to determine your response to metoprolol. Your doctor may ask you to check your pulse (heart rate). Ask your pharmacist or doctor to teach you how to take your pulse. If your pulse is faster or slower than it should be, call your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names of combination products

Dutoprol^® (containing Metoprolol, Hydrochlorothiazide)
Lopressidone^® (containing Chlorthalidone, Metoprolol)
Lopressor^® HCT (containing Metoprolol, Hydrochlorothiazide)

Drug interactions

Drug	Interaction
Repaglinide	Repaglinide The therapeutic efficacy of Repaglinide can be increased when used in combination with Metoprolol.
Insulin Glargine (rDNA origin) Injection	Insulin Glargine (rDNA origin) Injection The therapeutic efficacy of Insulin glargine can be increased when used in combination with Metoprolol.
Delavirdine	Delavirdine The metabolism of Metoprolol can be decreased when combined with Delavirdine.
Nevirapine	Nevirapine The metabolism of Metoprolol can be decreased when combined with Nevirapine.
Dolasetron	Dolasetron The metabolism of Dolasetron can be decreased when combined with Metoprolol.
Aminophylline	Aminophylline The metabolism of Aminophylline can be decreased when combined with Metoprolol.
Calcium Carbonate	Calcium Carbonate The therapeutic efficacy of Metoprolol can be decreased when used in combination with Calcium carbonate.
Candesartan	Candesartan The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Candesartan.
Cilostazol	Cilostazol The metabolism of Cilostazol can be decreased when combined with Metoprolol.
Erythromycin and Sulfisoxazole	Erythromycin and Sulfisoxazole The metabolism of Metoprolol can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives)	Estrogen and Progestin (Oral Contraceptives) Metoprolol may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate	Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Metoprolol.
Guanfacine	Guanfacine The therapeutic efficacy of Guanfacine can be decreased when used in combination with Metoprolol.
Magnesium Hydroxide	Magnesium Hydroxide Metoprolol may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Methylergonovine	Methylergonovine Metoprolol may increase the vasoconstricting activities of Methylergometrine.
Miglitol	Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Metoprolol.
Mycophenolate	Mycophenolate Metoprolol may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level.
Naratriptan	Naratriptan Naratriptan may decrease the antihypertensive activities of Metoprolol.
Olsalazine	Olsalazine Olsalazine may decrease the antihypertensive activities of Metoprolol.
Paregoric	Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Metoprolol.
Penbutolol	Penbutolol The metabolism of Acebutolol can be decreased when combined with Metoprolol.
Potassium	Potassium Potassium may increase the excretion rate of Metoprolol which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone	Prednisone Metoprolol may decrease the excretion rate of Prednisone which could result in a higher serum level.
Ranitidine	Ranitidine The serum concentration of Ranitidine can be increased when it is combined with Metoprolol.
Reserpine	Reserpine Reserpine may increase the hypotensive activities of Metoprolol.
Rizatriptan	Rizatriptan Metoprolol may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Sumatriptan	Sumatriptan Sumatriptan may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Tacrolimus	Tacrolimus The metabolism of Tacrolimus can be decreased when combined with Metoprolol.
Tizanidine	Tizanidine The therapeutic efficacy of Tizanidine can be decreased when used in combination with Metoprolol.
Triamcinolone	Triamcinolone The metabolism of Metoprolol can be increased when combined with Triamcinolone.
Zolmitriptan	Zolmitriptan Zolmitriptan may decrease the antihypertensive activities of Metoprolol.
Ampicillin Injection	Ampicillin Injection Metoprolol may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Doxycycline Injection	Doxycycline Injection The metabolism of Metoprolol can be decreased when combined with Doxycycline.
Fluconazole Injection	Fluconazole Injection The metabolism of Metoprolol can be decreased when combined with Fluconazole.
Foscarnet Injection	Foscarnet Injection Foscarnet may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Hydromorphone Injection	Hydromorphone Injection Metoprolol may decrease the excretion rate of Hydromorphone which could result in a higher serum level.
Levofloxacin Injection	Levofloxacin Injection Metoprolol may decrease the excretion rate of Levofloxacin which could result in a higher serum level.
Meperidine Injection	Meperidine Injection The metabolism of Meperidine can be decreased when combined with Metoprolol.
Methylprednisolone Injection	Methylprednisolone Injection The metabolism of Metoprolol can be increased when combined with Methylprednisolone.
Metoclopramide Injection	Metoclopramide Injection The metabolism of Metoclopramide can be decreased when combined with Metoprolol.
Metronidazole Injection	Metronidazole Injection The metabolism of Metoprolol can be decreased when combined with Metronidazole.
Morphine Injection	Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Metoprolol.
Pamidronate Injection	Pamidronate Injection Pamidronic acid may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Vancomycin Injection	Vancomycin Injection Metoprolol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Altretamine	Altretamine The metabolism of Metoprolol can be decreased when combined with Amphetamine.
Cefuroxime	Cefuroxime Cefuroxime may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Cyclosporine	Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Metoprolol.
Ondansetron	Ondansetron The metabolism of Ondansetron can be decreased when combined with Metoprolol.
Enoxaparin Injection	Enoxaparin Injection The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Enoxaparin.
Torsemide	Torsemide Torasemide may increase the excretion rate of Metoprolol which could result in a lower serum level and potentially a reduction in efficacy.
Olanzapine	Olanzapine The metabolism of Olanzapine can be decreased when combined with Metoprolol.
Dofetilide	Dofetilide Metoprolol may increase the arrhythmogenic activities of Dofetilide.
Entacapone	Entacapone The metabolism of Metoprolol can be decreased when combined with Entacapone.
Eprosartan	Eprosartan The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Eprosartan.
Hydroxychloroquine	Hydroxychloroquine The metabolism of Metoprolol can be decreased when combined with Hydroxychloroquine.
Meloxicam	Meloxicam Meloxicam may decrease the antihypertensive activities of Metoprolol.
Orlistat	Orlistat The metabolism of Metoprolol can be increased when combined with Orlistat.
Oxcarbazepine	Oxcarbazepine The metabolism of Metoprolol can be increased when combined with Oxcarbazepine.
Pantoprazole	Pantoprazole Pantoprazole may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Telmisartan	Telmisartan The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Telmisartan.
Temozolomide	Temozolomide Metoprolol may decrease the excretion rate of Temozolomide which could result in a higher serum level.
Zaleplon	Zaleplon Metoprolol may decrease the excretion rate of Zaleplon which could result in a higher serum level.
Anakinra	Anakinra The metabolism of Metoprolol can be increased when combined with Anakinra.
Linezolid	Linezolid Linezolid may increase the hypotensive activities of Metoprolol.
Rivastigmine	Rivastigmine Metoprolol may increase the bradycardic activities of Rivastigmine.
Trimipramine	Trimipramine The metabolism of Trimipramine can be decreased when combined with Metoprolol.
Etanercept Injection	Etanercept Injection The metabolism of Metoprolol can be increased when combined with Etanercept.
Modafinil	Modafinil The metabolism of Metoprolol can be increased when combined with Modafinil.
Perindopril	Perindopril Metoprolol may increase the hypotensive activities of Perindopril.
Tenofovir	Tenofovir Tenofovir may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Choline Magnesium Trisalicylate	Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the antihypertensive activities of Metoprolol.
Sirolimus	Sirolimus The metabolism of Sirolimus can be decreased when combined with Metoprolol.
Dutasteride	Dutasteride Dutasteride may decrease the antihypertensive activities of Metoprolol.
Epinephrine Injection	Epinephrine Injection The therapeutic efficacy of Epinephrine can be decreased when used in combination with Metoprolol.
Eplerenone	Eplerenone Metoprolol may increase the excretion rate of Eplerenone which could result in a lower serum level and potentially a reduction in efficacy.
Escitalopram	Escitalopram The serum concentration of Escitalopram can be increased when it is combined with Metoprolol.
Olmesartan	Olmesartan The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Olmesartan.
Zonisamide	Zonisamide The risk or severity of bradycardia can be increased when Zonisamide is combined with Metoprolol.
Adalimumab Injection	Adalimumab Injection The metabolism of Metoprolol can be increased when combined with Adalimumab.
Aripiprazole	Aripiprazole The metabolism of Metoprolol can be decreased when combined with Aripiprazole.
Atomoxetine	Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Metoprolol.
Dexmethylphenidate	Dexmethylphenidate Dexmethylphenidate may decrease the antihypertensive activities of Metoprolol.
Atazanavir	Atazanavir The metabolism of Metoprolol can be decreased when combined with Atazanavir.
Almotriptan	Almotriptan The metabolism of Almotriptan can be decreased when combined with Metoprolol.
Eletriptan	Eletriptan The metabolism of Eletriptan can be decreased when combined with Metoprolol.
Mefloquine	Mefloquine The risk or severity of QTc prolongation can be decreased when Mefloquine is combined with Metoprolol.
Rosuvastatin	Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Metoprolol.
Vardenafil	Vardenafil Vardenafil may increase the antihypertensive activities of Metoprolol.
Alfuzosin	Alfuzosin Alfuzosin may increase the hypotensive activities of Metoprolol.
Aprepitant	Aprepitant The metabolism of Metoprolol can be decreased when combined with Aprepitant.
Emtricitabine	Emtricitabine Metoprolol may decrease the excretion rate of Emtricitabine which could result in a higher serum level.
Memantine	Memantine Memantine may increase the bradycardic activities of Metoprolol.
Tegaserod	Tegaserod The metabolism of Tegaserod can be decreased when combined with Metoprolol.
Tadalafil	Tadalafil Metoprolol may increase the antihypertensive activities of Tadalafil.
Frovatriptan	Frovatriptan Frovatriptan may decrease the antihypertensive activities of Metoprolol.
Progesterone	Progesterone The metabolism of Metoprolol can be decreased when combined with Progesterone.
Apomorphine Injection	Apomorphine Injection The risk or severity of adverse effects can be increased when Apomorphine is combined with Metoprolol.
Infliximab Injection	Infliximab Injection The metabolism of Metoprolol can be increased when combined with Infliximab.
Protriptyline	Protriptyline The metabolism of Protriptyline can be decreased when combined with Metoprolol.
Rifaximin	Rifaximin The metabolism of Metoprolol can be increased when combined with Rifaximin.
Duloxetine	Duloxetine The risk or severity of orthostatic hypotension and syncope can be increased when Metoprolol is combined with Duloxetine.
Norethindrone	Norethindrone The metabolism of Norethisterone can be decreased when combined with Metoprolol.
Tinidazole	Tinidazole Metoprolol may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Trospium	Trospium The metabolism of Metoprolol can be decreased when combined with Trospium.
Bosentan	Bosentan The metabolism of Metoprolol can be increased when combined with Bosentan.
Cefditoren	Cefditoren Metoprolol may decrease the excretion rate of Cefdinir which could result in a higher serum level.
Cinacalcet	Cinacalcet The metabolism of Metoprolol can be decreased when combined with Cinacalcet.
Cyanocobalamin Injection	Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Erlotinib	Erlotinib The metabolism of Metoprolol can be decreased when combined with Erlotinib.
Eszopiclone	Eszopiclone Metoprolol may decrease the excretion rate of Eszopiclone which could result in a higher serum level.
Ganciclovir	Ganciclovir Metoprolol may decrease the excretion rate of Ganciclovir which could result in a higher serum level.
Insulin Aspart (rDNA Origin) Injection	Insulin Aspart (rDNA Origin) Injection The therapeutic efficacy of Insulin aspart can be increased when used in combination with Metoprolol.
Ribavirin	Ribavirin Metoprolol may decrease the excretion rate of Ribavirin which could result in a higher serum level.
Solifenacin	Solifenacin The metabolism of Solifenacin can be decreased when combined with Metoprolol.
Valganciclovir	Valganciclovir Metoprolol may decrease the excretion rate of Valganciclovir which could result in a higher serum level.
Voriconazole	Voriconazole The metabolism of Metoprolol can be decreased when combined with Voriconazole.
Adefovir	Adefovir Adefovir may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Dextroamphetamine	Dextroamphetamine The metabolism of Metoprolol can be decreased when combined with Amphetamine.
Peginterferon Alfa-2b (PEG-Intron)	Peginterferon Alfa-2b (PEG-Intron) The metabolism of Metoprolol can be decreased when combined with Peginterferon alfa-2b.
Pramlintide Injection	Pramlintide Injection The therapeutic efficacy of Pramlintide can be increased when used in combination with Metoprolol.
Exenatide Injection	Exenatide Injection The therapeutic efficacy of Exenatide can be increased when used in combination with Metoprolol.
Isocarboxazid	Isocarboxazid Isocarboxazid may increase the hypotensive activities of Metoprolol.
Ramelteon	Ramelteon Metoprolol may decrease the excretion rate of Ramelteon which could result in a higher serum level.
Darifenacin	Darifenacin The metabolism of Darifenacin can be decreased when combined with Metoprolol.
Fentanyl	Fentanyl Fentanyl may decrease the antihypertensive activities of Metoprolol.
Pregabalin	Pregabalin Pregabalin may increase the arrhythmogenic activities of Metoprolol.
Deferasirox	Deferasirox The metabolism of Metoprolol can be increased when combined with Deferasirox.
Phenylephrine	Phenylephrine The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Metoprolol.
Tipranavir	Tipranavir The metabolism of Tipranavir can be decreased when combined with Metoprolol.
Felbamate	Felbamate The metabolism of Metoprolol can be increased when combined with Felbamate.
Insulin Detemir (rDNA Origin) Injection	Insulin Detemir (rDNA Origin) Injection The therapeutic efficacy of Insulin detemir can be increased when used in combination with Metoprolol.
Ranolazine	Ranolazine The serum concentration of Metoprolol can be increased when it is combined with Ranolazine.
Abatacept Injection	Abatacept Injection The metabolism of Metoprolol can be increased when combined with Abatacept.
Rasagiline	Rasagiline Rasagiline may increase the hypotensive activities of Metoprolol.
Imatinib	Imatinib The metabolism of Metoprolol can be decreased when combined with Imatinib.
Sitagliptin	Sitagliptin The therapeutic efficacy of Sitagliptin can be increased when used in combination with Metoprolol.
Varenicline	Varenicline The excretion of Varenicline can be decreased when combined with Metoprolol.
Gefitinib	Gefitinib The metabolism of Metoprolol can be decreased when combined with Gefitinib.
Albuterol	Albuterol The therapeutic efficacy of Salbutamol can be decreased when used in combination with Metoprolol.
Paliperidone	Paliperidone The metabolism of Metoprolol can be decreased when combined with Paliperidone.
Bortezomib	Bortezomib The metabolism of Bortezomib can be decreased when combined with Metoprolol.
Clofarabine Injection	Clofarabine Injection The serum concentration of Clofarabine can be increased when it is combined with Metoprolol.
Insulin Glulisine (rDNA origin) Injection	Insulin Glulisine (rDNA origin) Injection The therapeutic efficacy of Insulin glulisine can be increased when used in combination with Metoprolol.
Lubiprostone	Lubiprostone Metoprolol may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
Oxaliplatin Injection	Oxaliplatin Injection The serum concentration of Oxaliplatin can be increased when it is combined with Metoprolol.
Posaconazole	Posaconazole The metabolism of Metoprolol can be decreased when combined with Posaconazole.
Primaquine	Primaquine The metabolism of Metoprolol can be decreased when combined with Primaquine.
Rituximab Injection	Rituximab Injection Metoprolol may increase the hypotensive activities of Rituximab.
Aliskiren	Aliskiren The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Aliskiren.
Darunavir	Darunavir The metabolism of Darunavir can be decreased when combined with Metoprolol.
Pemetrexed Injection	Pemetrexed Injection Metoprolol may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Lisdexamfetamine	Lisdexamfetamine The metabolism of Metoprolol can be decreased when combined with Lisdexamfetamine.
Nabilone	Nabilone The risk or severity of adverse effects can be increased when Nabilone is combined with Metoprolol.
Sorafenib	Sorafenib The metabolism of Metoprolol can be decreased when combined with Sorafenib.
Sunitinib	Sunitinib The therapeutic efficacy of Metoprolol can be increased when used in combination with Sunitinib.
Lapatinib	Lapatinib The metabolism of Metoprolol can be decreased when combined with Lapatinib.
Levocetirizine	Levocetirizine Metoprolol may decrease the excretion rate of Levocetirizine which could result in a higher serum level.
Pegaptanib Injection	Pegaptanib Injection Metoprolol may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Dasatinib	Dasatinib The metabolism of Dasatinib can be decreased when combined with Metoprolol.
Mexiletine	Mexiletine The metabolism of Mexiletine can be decreased when combined with Metoprolol.
Armodafinil	Armodafinil The metabolism of Metoprolol can be increased when combined with Armodafinil.
Azacitidine Injection	Azacitidine Injection Metoprolol may decrease the excretion rate of Azacitidine which could result in a higher serum level.
Ivermectin	Ivermectin The metabolism of Metoprolol can be increased when combined with Ivermectin.
Temsirolimus	Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Metoprolol.
Lenalidomide	Lenalidomide Metoprolol may decrease the excretion rate of Lenalidomide which could result in a higher serum level.
Nilotinib	Nilotinib The metabolism of Metoprolol can be decreased when combined with Nilotinib.
Bexarotene	Bexarotene The metabolism of Metoprolol can be increased when combined with Bexarotene.
Budesonide	Budesonide The metabolism of Metoprolol can be increased when combined with Budesonide.
Chloramphenicol Injection	Chloramphenicol Injection The metabolism of Metoprolol can be decreased when combined with Chloramphenicol.
Desmopressin	Desmopressin Desmopressin may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Betaine	Betaine Glycine betaine may increase the bradycardic activities of Metoprolol.
Doripenem Injection	Doripenem Injection Metoprolol may decrease the excretion rate of Doripenem which could result in a higher serum level.
Etravirine	Etravirine The metabolism of Metoprolol can be increased when combined with Etravirine.
Arsenic Trioxide Injection	Arsenic Trioxide Injection Metoprolol may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level.
Mitoxantrone Injection	Mitoxantrone Injection The metabolism of Metoprolol can be decreased when combined with Mitoxantrone.
Desvenlafaxine	Desvenlafaxine The serum concentration of Metoprolol can be increased when it is combined with Desvenlafaxine.
Cevimeline	Cevimeline The metabolism of Metoprolol can be decreased when combined with Cevimeline.
Nebivolol	Nebivolol The metabolism of Nebivolol can be decreased when combined with Metoprolol.
Tretinoin	Tretinoin The risk or severity of adverse effects can be increased when Tretinoin is combined with Metoprolol.
Pilocarpine	Pilocarpine The metabolism of Metoprolol can be decreased when combined with Pilocarpine.
Flecainide	Flecainide The metabolism of Flecainide can be decreased when combined with Metoprolol.
Certolizumab Injection	Certolizumab Injection The metabolism of Metoprolol can be increased when combined with Certolizumab pegol.
Ixabepilone Injection	Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Metoprolol.
Irinotecan Injection	Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Metoprolol.
Daptomycin Injection	Daptomycin Injection Daptomycin may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Mitotane	Mitotane The metabolism of Metoprolol can be increased when combined with Mitotane.
Methylnaltrexone Injection	Methylnaltrexone Injection Metoprolol may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Rufinamide	Rufinamide The metabolism of Metoprolol can be increased when combined with Rufinamide.
Silodosin	Silodosin Metoprolol may increase the orthostatic hypotensive activities of Silodosin.
Midazolam	Midazolam The metabolism of Midazolam can be decreased when combined with Metoprolol.
Dexrazoxane Injection	Dexrazoxane Injection Metoprolol may decrease the excretion rate of Dexrazoxane which could result in a higher serum level.
Milnacipran	Milnacipran The serum concentration of Metoprolol can be increased when it is combined with Milnacipran.
Plerixafor Injection	Plerixafor Injection Metoprolol may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Sodium Phosphate	Sodium Phosphate Sodium phosphate, monobasic may increase the hyperkalemic activities of Metoprolol.
Fesoterodine	Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Metoprolol.
Betaxolol	Betaxolol The metabolism of Betaxolol can be decreased when combined with Metoprolol.
Iloperidone	Iloperidone The metabolism of Iloperidone can be decreased when combined with Metoprolol.
Prasugrel	Prasugrel Metoprolol may decrease the excretion rate of Prasugrel which could result in a higher serum level.
Lacosamide	Lacosamide The metabolism of Lacosamide can be decreased when combined with Metoprolol.
Everolimus	Everolimus The metabolism of Everolimus can be decreased when combined with Metoprolol.
Tolvaptan (low blood sodium)	Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be decreased when combined with Metoprolol.
Dronedarone	Dronedarone Dronedarone may increase the bradycardic activities of Metoprolol.
Pralatrexate Injection	Pralatrexate Injection Metoprolol may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection	Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Metoprolol.
Saxagliptin	Saxagliptin The therapeutic efficacy of Saxagliptin can be increased when used in combination with Metoprolol.
Telavancin Injection	Telavancin Injection Metoprolol may decrease the excretion rate of Telavancin which could result in a higher serum level.
Romidepsin Injection	Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Metoprolol.
Tapentadol	Tapentadol The metabolism of Tapentadol can be decreased when combined with Metoprolol.
Topotecan	Topotecan The metabolism of Metoprolol can be decreased when combined with Topotecan.
Golimumab Injection	Golimumab Injection The metabolism of Metoprolol can be increased when combined with Golimumab.
Pazopanib	Pazopanib The metabolism of Pazopanib can be decreased when combined with Metoprolol.
Asenapine	Asenapine Metoprolol may increase the orthostatic hypotensive activities of Asenapine.
Albendazole	Albendazole The metabolism of Albendazole can be decreased when combined with Metoprolol.
Oxymorphone	Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Metoprolol.
Liraglutide Injection	Liraglutide Injection The therapeutic efficacy of Liraglutide can be increased when used in combination with Metoprolol.
Tocilizumab Injection	Tocilizumab Injection The metabolism of Metoprolol can be increased when combined with Tocilizumab.
Dalfampridine	Dalfampridine The serum concentration of Dalfampridine can be increased when it is combined with Metoprolol.
Fingolimod	Fingolimod Metoprolol may increase the bradycardic activities of Fingolimod.
Cabazitaxel Injection	Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Metoprolol.
Ceftaroline Injection	Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Lurasidone	Lurasidone Lurasidone may decrease the antihypertensive activities of Metoprolol.
Acetaminophen Injection	Acetaminophen Injection The metabolism of Metoprolol can be decreased when combined with Acetaminophen.
Vilazodone	Vilazodone The metabolism of Vilazodone can be decreased when combined with Metoprolol.
Ipilimumab Injection	Ipilimumab Injection Metoprolol may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection	Denileukin Diftitox Injection The metabolism of Metoprolol can be decreased when combined with Aldesleukin.
Terbutaline Injection	Terbutaline Injection The therapeutic efficacy of Terbutaline can be decreased when used in combination with Metoprolol.
Azilsartan	Azilsartan The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Azilsartan medoxomil.
Busulfan Injection	Busulfan Injection The metabolism of Busulfan can be decreased when combined with Metoprolol.
Roflumilast	Roflumilast The metabolism of Roflumilast can be decreased when combined with Metoprolol.
Linagliptin	Linagliptin The therapeutic efficacy of Linagliptin can be increased when used in combination with Metoprolol.
Rilpivirine	Rilpivirine The metabolism of Metoprolol can be decreased when combined with Rilpivirine.
Telaprevir	Telaprevir The metabolism of Metoprolol can be decreased when combined with Glecaprevir.
Potassium Iodide	Potassium Iodide Potassium Iodide may increase the hyperkalemic activities of Metoprolol.
Cyclophosphamide Injection	Cyclophosphamide Injection The metabolism of Metoprolol can be decreased when combined with Cyclophosphamide.
Abiraterone	Abiraterone The metabolism of Metoprolol can be decreased when combined with Abiraterone.
Rivaroxaban	Rivaroxaban Metoprolol may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ticagrelor	Ticagrelor The metabolism of Metoprolol can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection	Brentuximab Vedotin Injection The metabolism of Metoprolol can be decreased when combined with Brentuximab vedotin.
Ruxolitinib	Ruxolitinib Ruxolitinib may increase the bradycardic activities of Metoprolol.
Vandetanib	Vandetanib The metabolism of Vandetanib can be decreased when combined with Metoprolol.
Clobazam	Clobazam The metabolism of Clobazam can be decreased when combined with Metoprolol.
Vemurafenib	Vemurafenib The metabolism of Metoprolol can be decreased when combined with Vemurafenib.
Ivacaftor	Ivacaftor The metabolism of Metoprolol can be decreased when combined with Ivacaftor.
Deferiprone	Deferiprone Metoprolol may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Axitinib	Axitinib The metabolism of Axitinib can be decreased when combined with Metoprolol.
Crizotinib	Crizotinib The metabolism of Metoprolol can be decreased when combined with Crizotinib.
Cabergoline	Cabergoline The metabolism of Cabergoline can be decreased when combined with Metoprolol.
Naloxone Injection	Naloxone Injection The metabolism of Metoprolol can be decreased when combined with Naloxone.
Ambrisentan	Ambrisentan Metoprolol may increase the hypotensive activities of Ambrisentan.
Fondaparinux Injection	Fondaparinux Injection Metoprolol may decrease the excretion rate of Fondaparinux which could result in a higher serum level.
Iloprost	Iloprost Iloprost may increase the hypotensive activities of Metoprolol.
Enzalutamide	Enzalutamide The metabolism of Metoprolol can be increased when combined with Enzalutamide.
Mirabegron	Mirabegron Mirabegron may decrease the antihypertensive activities of Metoprolol.
Regorafenib	Regorafenib Regorafenib may increase the bradycardic activities of Metoprolol.
Bosutinib	Bosutinib The metabolism of Metoprolol can be decreased when combined with Bosutinib.
Corticotropin, Repository Injection	Corticotropin, Repository Injection The metabolism of Metoprolol can be increased when combined with Corticotropin.
Lorcaserin	Lorcaserin The therapeutic efficacy of Mecasermin can be increased when used in combination with Metoprolol.
Teduglutide Injection	Teduglutide Injection Metoprolol may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Tofacitinib	Tofacitinib Metoprolol may increase the bradycardic activities of Tofacitinib.
Alogliptin	Alogliptin The metabolism of Alogliptin can be decreased when combined with Metoprolol.
Ponatinib	Ponatinib The metabolism of Metoprolol can be decreased when combined with Ponatinib.
Pomalidomide	Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Metoprolol.
Ado-trastuzumab Emtansine Injection	Ado-trastuzumab Emtansine Injection The metabolism of Metoprolol can be decreased when combined with Trastuzumab emtansine.
Canagliflozin	Canagliflozin The therapeutic efficacy of Metoprolol can be increased when used in combination with Canagliflozin.
Methazolamide	Methazolamide Methazolamide may increase the excretion rate of Metoprolol which could result in a lower serum level and potentially a reduction in efficacy.
Dabrafenib	Dabrafenib The metabolism of Metoprolol can be decreased when combined with Dabrafenib.
Ospemifene	Ospemifene The metabolism of Metoprolol can be decreased when combined with Ospemifene.
Trametinib	Trametinib The metabolism of Trametinib can be increased when combined with Metoprolol.
Levomilnacipran	Levomilnacipran The metabolism of Metoprolol can be decreased when combined with Levomilnacipran.
Ertapenem Injection	Ertapenem Injection Metoprolol may decrease the excretion rate of Ertapenem which could result in a higher serum level.
Vortioxetine	Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Metoprolol.
Perampanel	Perampanel The metabolism of Metoprolol can be increased when combined with Perampanel.
Ibrutinib	Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Metoprolol.
Lomitapide	Lomitapide The metabolism of Metoprolol can be decreased when combined with Lomitapide.
Avanafil	Avanafil Avanafil may increase the antihypertensive activities of Metoprolol.
Ketorolac Injection	Ketorolac Injection Ketorolac may decrease the antihypertensive activities of Metoprolol.
Obinutuzumab Injection	Obinutuzumab Injection Metoprolol may increase the hypotensive activities of Obinutuzumab.
Simeprevir	Simeprevir The metabolism of Metoprolol can be decreased when combined with Simeprevir.
Sofosbuvir	Sofosbuvir Metoprolol may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin	Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Metoprolol.
Apremilast	Apremilast The metabolism of Metoprolol can be increased when combined with Apremilast.
Droxidopa	Droxidopa The therapeutic efficacy of Droxidopa can be decreased when used in combination with Metoprolol.
Ceritinib	Ceritinib Metoprolol may increase the bradycardic activities of Ceritinib.
Siltuximab Injection	Siltuximab Injection The metabolism of Metoprolol can be increased when combined with Siltuximab.
Albiglutide Injection	Albiglutide Injection The therapeutic efficacy of Albiglutide can be increased when used in combination with Metoprolol.
Eslicarbazepine	Eslicarbazepine The metabolism of Metoprolol can be increased when combined with Eslicarbazepine.
Idelalisib	Idelalisib The metabolism of Idelalisib can be decreased when combined with Metoprolol.
Testosterone Injection	Testosterone Injection The metabolism of Metoprolol can be increased when combined with Testosterone.
Oritavancin Injection	Oritavancin Injection The metabolism of Metoprolol can be increased when combined with Oritavancin.
Empagliflozin	Empagliflozin The therapeutic efficacy of Empagliflozin can be increased when used in combination with Metoprolol.
Vorapaxar	Vorapaxar The metabolism of Vorapaxar can be decreased when combined with Metoprolol.
Hydrocodone	Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Metoprolol.
Suvorexant	Suvorexant The metabolism of Suvorexant can be decreased when combined with Metoprolol.
Dulaglutide Injection	Dulaglutide Injection The therapeutic efficacy of Dulaglutide can be increased when used in combination with Metoprolol.
Edoxaban	Edoxaban Metoprolol may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Olaparib	Olaparib The metabolism of Metoprolol can be decreased when combined with Olaparib.
Methamphetamine	Methamphetamine The metabolism of Metoprolol can be decreased when combined with Metamfetamine.
Tasimelteon	Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Metoprolol.
Riociguat	Riociguat Metoprolol may increase the hypotensive activities of Riociguat.
Lanreotide Injection	Lanreotide Injection Metoprolol may increase the bradycardic activities of Lanreotide.
Nintedanib	Nintedanib The metabolism of Nintedanib can be decreased when combined with Metoprolol.
Secukinumab Injection	Secukinumab Injection The metabolism of Metoprolol can be increased when combined with Secukinumab.
Risperidone Injection	Risperidone Injection Metoprolol may increase the hypotensive activities of Risperidone.
Palbociclib	Palbociclib The metabolism of Metoprolol can be decreased when combined with Palbociclib.
Insulin Human Inhalation	Insulin Human Inhalation The therapeutic efficacy of Insulin human can be increased when used in combination with Metoprolol.
Lenvatinib	Lenvatinib The metabolism of Metoprolol can be decreased when combined with Lenvatinib.
Naloxegol	Naloxegol The metabolism of Metoprolol can be decreased when combined with Naloxegol.
Panobinostat	Panobinostat The metabolism of Metoprolol can be decreased when combined with Panobinostat.
Dinutuximab Injection	Dinutuximab Injection The risk or severity of adverse effects can be increased when Dinutuximab is combined with Metoprolol.
Haloperidol Injection	Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Metoprolol.
Ivabradine	Ivabradine Metoprolol may increase the bradycardic activities of Ivabradine.
Amiloride	Amiloride Metoprolol may increase the excretion rate of Amiloride which could result in a lower serum level and potentially a reduction in efficacy.
Isavuconazonium Injection	Isavuconazonium Injection The metabolism of Metoprolol can be increased when combined with Isavuconazonium.
Macitentan	Macitentan Metoprolol may decrease the excretion rate of Macitentan which could result in a higher serum level.
Sonidegib	Sonidegib The metabolism of Sonidegib can be decreased when combined with Metoprolol.
Flibanserin	Flibanserin Flibanserin may decrease the antihypertensive activities of Metoprolol.
Rolapitant	Rolapitant The metabolism of Metoprolol can be decreased when combined with Rolapitant.
Prednisolone	Prednisolone The metabolism of Metoprolol can be increased when combined with Prednisolone.
Brexpiprazole	Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Metoprolol.
Ziprasidone Injection	Ziprasidone Injection Metoprolol may increase the antihypertensive activities of Ziprasidone.
Cariprazine	Cariprazine The metabolism of Cariprazine can be decreased when combined with Metoprolol.
Penicillin G Procaine Injection	Penicillin G Procaine Injection Metoprolol may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Insulin Degludec (rDNA Origin) Injection	Insulin Degludec (rDNA Origin) Injection The therapeutic efficacy of Insulin degludec can be increased when used in combination with Metoprolol.
Cobimetinib	Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Metoprolol.
Trabectedin Injection	Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Metoprolol.
Osimertinib	Osimertinib The metabolism of Metoprolol can be decreased when combined with Osimertinib.
Alectinib	Alectinib The metabolism of Alectinib can be decreased when combined with Metoprolol.
Ixazomib	Ixazomib The metabolism of Ixazomib can be decreased when combined with Metoprolol.
Rifapentine	Rifapentine The metabolism of Metoprolol can be increased when combined with Rifapentine.
Lesinurad	Lesinurad The metabolism of Lesinurad can be increased when combined with Metoprolol.
Amphotericin B Liposomal Injection	Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Dexamethasone Injection	Dexamethasone Injection The metabolism of Metoprolol can be increased when combined with Dexamethasone.
Brivaracetam Injection	Brivaracetam Injection Metoprolol may decrease the excretion rate of Brivaracetam which could result in a higher serum level.
Venetoclax	Venetoclax The metabolism of Metoprolol can be decreased when combined with Venetoclax.
Cobicistat	Cobicistat The metabolism of Metoprolol can be decreased when combined with Cobicistat.
Midodrine	Midodrine The therapeutic efficacy of Midodrine can be decreased when used in combination with Metoprolol.
Selexipag	Selexipag Metoprolol may increase the hypotensive activities of Selexipag.
Diphenhydramine Injection	Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Metoprolol.
Furosemide Injection	Furosemide Injection Metoprolol may increase the excretion rate of Furosemide which could result in a lower serum level and potentially a reduction in efficacy.
Rucaparib	Rucaparib The metabolism of Metoprolol can be decreased when combined with Rucaparib.
Lixisenatide Injection	Lixisenatide Injection The therapeutic efficacy of Lixisenatide can be increased when used in combination with Metoprolol.
Ribociclib	Ribociclib The metabolism of Metoprolol can be decreased when combined with Ribociclib.
Brigatinib	Brigatinib The metabolism of Metoprolol can be decreased when combined with Brigatinib.
Doxepin (Insomnia)	Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Metoprolol.
Deutetrabenazine	Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Metoprolol.
Valbenazine	Valbenazine The metabolism of Valbenazine can be decreased when combined with Metoprolol.
Deflazacort	Deflazacort The metabolism of Metoprolol can be increased when combined with Deflazacort.
Safinamide	Safinamide Safinamide may increase the hypotensive activities of Metoprolol.
Naldemedine	Naldemedine Metoprolol may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Sarilumab Injection	Sarilumab Injection The metabolism of Metoprolol can be increased when combined with Sarilumab.
Midostaurin	Midostaurin The metabolism of Metoprolol can be increased when combined with Midostaurin.
Neratinib	Neratinib The metabolism of Neratinib can be decreased when combined with Metoprolol.
Enasidenib	Enasidenib The metabolism of Metoprolol can be decreased when combined with Enasidenib.
Aprepitant/Fosaprepitant Injection	Aprepitant/Fosaprepitant Injection The metabolism of Metoprolol can be increased when combined with Fosaprepitant.
Benznidazole	Benznidazole Metoprolol may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Copanlisib Injection	Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Metoprolol.
Delafloxacin	Delafloxacin Metoprolol may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib	Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Metoprolol.
Acalabrutinib	Acalabrutinib The metabolism of Metoprolol can be decreased when combined with Acalabrutinib.
Letermovir	Letermovir The metabolism of Metoprolol can be decreased when combined with Letermovir.
Semaglutide Injection	Semaglutide Injection The therapeutic efficacy of Semaglutide can be increased when used in combination with Metoprolol.
Tetrabenazine	Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Metoprolol.
Ertugliflozin	Ertugliflozin The therapeutic efficacy of Ertugliflozin can be increased when used in combination with Metoprolol.
Buprenorphine Injection	Buprenorphine Injection The metabolism of Metoprolol can be decreased when combined with Buprenorphine.
Apalutamide	Apalutamide The metabolism of Apalutamide can be increased when combined with Metoprolol.
Fostamatinib	Fostamatinib The metabolism of Metoprolol can be decreased when combined with Fostamatinib.
Baricitinib	Baricitinib The metabolism of Baricitinib can be decreased when combined with Metoprolol.
Lofexidine	Lofexidine The metabolism of Lofexidine can be decreased when combined with Metoprolol.
Plazomicin Injection	Plazomicin Injection Metoprolol may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Eliglustat	Eliglustat The metabolism of Eliglustat can be decreased when combined with Metoprolol.
Encorafenib	Encorafenib The metabolism of Encorafenib can be decreased when combined with Metoprolol.
Ivosidenib	Ivosidenib The metabolism of Metoprolol can be decreased when combined with Ivosidenib.
Elagolix	Elagolix The metabolism of Elagolix can be decreased when combined with Metoprolol.
Tafenoquine	Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Metoprolol.
Cannabidiol	Cannabidiol The metabolism of Metoprolol can be decreased when combined with Cannabidiol.
Dacomitinib	Dacomitinib The metabolism of Metoprolol can be decreased when combined with Dacomitinib.
Duvelisib	Duvelisib The metabolism of Duvelisib can be decreased when combined with Metoprolol.
Stiripentol	Stiripentol The metabolism of Metoprolol can be decreased when combined with Stiripentol.
Gilteritinib	Gilteritinib The metabolism of Gilteritinib can be decreased when combined with Metoprolol.
Paclitaxel (with albumin) Injection	Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Metoprolol.
Rifamycin	Rifamycin The metabolism of Metoprolol can be increased when combined with Rifamycin.
Prucalopride	Prucalopride The metabolism of Prucalopride can be decreased when combined with Metoprolol.
Emapalumab-lzsg Injection	Emapalumab-lzsg Injection The metabolism of Metoprolol can be increased when combined with Emapalumab.
Siponimod	Siponimod The metabolism of Siponimod can be decreased when combined with Metoprolol.
Acyclovir Ophthalmic	Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Erdafitinib	Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Metoprolol.
Alpelisib	Alpelisib The metabolism of Metoprolol can be decreased when combined with Alpelisib.
Solriamfetol	Solriamfetol The serum concentration of Solriamfetol can be increased when it is combined with Metoprolol.
Triclabendazole	Triclabendazole The metabolism of Triclabendazole can be decreased when combined with Metoprolol.
Entrectinib	Entrectinib The metabolism of Entrectinib can be decreased when combined with Metoprolol.
Pexidartinib	Pexidartinib The metabolism of Pexidartinib can be decreased when combined with Metoprolol.
Istradefylline	Istradefylline The metabolism of Istradefylline can be decreased when combined with Metoprolol.
Pitolisant	Pitolisant The serum concentration of Metoprolol can be decreased when it is combined with Pitolisant.
Fedratinib	Fedratinib The metabolism of Metoprolol can be decreased when combined with Fedratinib.
Lefamulin	Lefamulin The metabolism of Lefamulin can be decreased when combined with Metoprolol.
Phenytoin Injection	Phenytoin Injection The metabolism of Metoprolol can be increased when combined with Phenytoin.
Fosphenytoin Injection	Fosphenytoin Injection The metabolism of Metoprolol can be increased when combined with Fosphenytoin.
Zanubrutinib	Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Metoprolol.
Lasmiditan	Lasmiditan Lasmiditan may increase the bradycardic activities of Metoprolol.
Calcium Acetate	Calcium Acetate The therapeutic efficacy of Metoprolol can be decreased when used in combination with Calcium acetate.
Tazemetostat	Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Metoprolol.
Cenobamate	Cenobamate The serum concentration of Metoprolol can be decreased when it is combined with Cenobamate.
Tucatinib	Tucatinib The metabolism of Tucatinib can be decreased when combined with Metoprolol.
Selpercatinib	Selpercatinib Selpercatinib may decrease the antihypertensive activities of Metoprolol.
Fenfluramine	Fenfluramine The metabolism of Metoprolol can be decreased when combined with Fenfluramine.
Octreotide	Octreotide The serum concentration of the active metabolites of Metoprolol can be increased when Metoprolol is used in combination with Octreotide.
Pralsetinib	Pralsetinib The metabolism of Metoprolol can be increased when combined with Pralsetinib.
Satralizumab-mwge Injection	Satralizumab-mwge Injection The serum concentration of Metoprolol can be decreased when it is combined with Satralizumab.
Naxitamab-gqgk Injection	Naxitamab-gqgk Injection Naxitamab may decrease the antihypertensive activities of Metoprolol.
Progestin-Only (drospirenone) Oral Contraceptives	Progestin-Only (drospirenone) Oral Contraceptives Metoprolol may increase the excretion rate of Drospirenone which could result in a lower serum level and potentially a reduction in efficacy.
Viloxazine	Viloxazine Metoprolol may decrease the excretion rate of Viloxazine which could result in a higher serum level.
Vitamin E (Alpha-Tocopherol)	Vitamin E (Alpha-Tocopherol) The metabolism of Metoprolol can be increased when combined with Vitamin E.
Tobramycin Injection	Tobramycin Injection Tobramycin may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Theophylline	Theophylline The metabolism of Theophylline can be decreased when combined with Metoprolol.
Fenoprofen	Fenoprofen Fenoprofen may decrease the antihypertensive activities of Metoprolol.
Indomethacin	Indomethacin Indomethacin may decrease the antihypertensive activities of Metoprolol.
Mefenamic Acid	Mefenamic Acid Mefenamic acid may decrease the antihypertensive activities of Metoprolol.
Naproxen	Naproxen Naproxen may decrease the antihypertensive activities of Metoprolol.
Tolmetin	Tolmetin Tolmetin may decrease the antihypertensive activities of Metoprolol.
Sulindac	Sulindac Sulindac may decrease the antihypertensive activities of Metoprolol.
Trazodone	Trazodone The metabolism of Metoprolol can be decreased when combined with Trazodone.
Isotretinoin	Isotretinoin Metoprolol may decrease the excretion rate of Isotretinoin which could result in a higher serum level.
Sucralfate	Sucralfate Metoprolol may decrease the excretion rate of Sucralfate which could result in a higher serum level.
Hydroxyurea	Hydroxyurea The metabolism of Metoprolol can be decreased when combined with Hydroxyurea.
Floxuridine	Floxuridine Metoprolol may decrease the excretion rate of Floxuridine which could result in a higher serum level.
Phenobarbital	Phenobarbital The metabolism of Metoprolol can be increased when combined with Phenobarbital.
Metaxalone	Metaxalone Metoprolol may decrease the excretion rate of Metaxalone which could result in a higher serum level.
Methotrexate Injection	Methotrexate Injection The metabolism of Metoprolol can be decreased when combined with Methotrexate.
Primidone	Primidone The metabolism of Metoprolol can be increased when combined with Primidone.
Methsuximide	Methsuximide The risk or severity of bradycardia can be increased when Methsuximide is combined with Metoprolol.
Diethylpropion	Diethylpropion The therapeutic efficacy of Metoprolol can be decreased when used in combination with Diethylpropion.
Chlorpromazine	Chlorpromazine The metabolism of Metoprolol can be decreased when combined with Chlorpromazine.
Diazepam	Diazepam The metabolism of Metoprolol can be decreased when combined with Diazepam.
Oxazepam	Oxazepam Metoprolol may decrease the excretion rate of Oxazepam which could result in a higher serum level.
Flurazepam	Flurazepam Metoprolol may decrease the excretion rate of Flurazepam which could result in a higher serum level.
Clorazepate	Clorazepate Metoprolol may decrease the excretion rate of Clorazepic acid which could result in a higher serum level.
Phenoxybenzamine	Phenoxybenzamine Metoprolol may increase the orthostatic hypotensive activities of Phenoxybenzamine.
Carmustine	Carmustine Carmustine may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Amantadine	Amantadine The serum concentration of Amantadine can be increased when it is combined with Metoprolol.
Codeine	Codeine The metabolism of Codeine can be decreased when combined with Metoprolol.
Bromocriptine	Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Metoprolol.
Metaproterenol	Metaproterenol The therapeutic efficacy of Orciprenaline can be decreased when used in combination with Metoprolol.
Tranylcypromine	Tranylcypromine The metabolism of Metoprolol can be decreased when combined with Tranylcypromine.
Phenelzine	Phenelzine Phenelzine may increase the hypotensive activities of Metoprolol.
Procarbazine	Procarbazine Procarbazine may increase the hypotensive activities of Metoprolol.
Ergoloid Mesylates	Ergoloid Mesylates Metoprolol may increase the vasoconstricting activities of Ergoloid mesylate.
Tetracycline	Tetracycline The metabolism of Metoprolol can be decreased when combined with Tetracycline.
Prochlorperazine	Prochlorperazine The metabolism of Metoprolol can be decreased when combined with Prochlorperazine.
Thioridazine	Thioridazine The metabolism of Metoprolol can be decreased when combined with Thioridazine.
Trifluoperazine	Trifluoperazine The serum concentration of Metoprolol can be increased when it is combined with Trifluoperazine.
Bleomycin	Bleomycin Metoprolol may decrease the excretion rate of Bleomycin which could result in a higher serum level.
Sulfadiazine	Sulfadiazine The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Metoprolol.
Oxycodone	Oxycodone The metabolism of Oxycodone can be decreased when combined with Metoprolol.
Methadone	Methadone The metabolism of Methadone can be decreased when combined with Metoprolol.
Oxybutynin	Oxybutynin The metabolism of Metoprolol can be decreased when combined with Oxybutynin.
Benztropine	Benztropine The metabolism of Metoprolol can be decreased when combined with Benzatropine.
Maprotiline	Maprotiline The metabolism of Maprotiline can be decreased when combined with Metoprolol.
Ibuprofen	Ibuprofen Ibuprofen may decrease the antihypertensive activities of Metoprolol.
Orphenadrine	Orphenadrine The metabolism of Metoprolol can be decreased when combined with Orphenadrine.
Perphenazine	Perphenazine The metabolism of Metoprolol can be decreased when combined with Perphenazine.
Azathioprine	Azathioprine Metoprolol may decrease the excretion rate of Azathioprine which could result in a higher serum level.
Fluphenazine	Fluphenazine The serum concentration of Metoprolol can be increased when it is combined with Fluphenazine.
Phentermine	Phentermine The therapeutic efficacy of Metoprolol can be decreased when used in combination with Phentermine.
Methylphenidate	Methylphenidate Methylphenidate may decrease the antihypertensive activities of Metoprolol.
Amoxapine	Amoxapine The metabolism of Amoxapine can be decreased when combined with Metoprolol.
Sulfasalazine	Sulfasalazine Sulfasalazine may decrease the antihypertensive activities of Metoprolol.
Hydrocortisone	Hydrocortisone The metabolism of Metoprolol can be increased when combined with Hydrocortisone.
Doxorubicin	Doxorubicin The metabolism of Metoprolol can be decreased when combined with Doxorubicin.
Mechlorethamine	Mechlorethamine Mechlorethamine may increase the bradycardic activities of Metoprolol.
Pyridostigmine	Pyridostigmine Pyridostigmine may increase the bradycardic activities of Metoprolol.
Phenazopyridine	Phenazopyridine Phenazopyridine may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Carbamazepine	Carbamazepine The metabolism of Carbamazepine can be increased when combined with Metoprolol.
Methyldopa	Methyldopa The therapeutic efficacy of Methyldopa can be decreased when used in combination with Metoprolol.
Clonidine	Clonidine The risk or severity of hypotension can be increased when Clonidine is combined with Metoprolol.
Prazosin	Prazosin The risk or severity of hypotension can be increased when Prazosin is combined with Metoprolol.
Hydralazine	Hydralazine The metabolism of Hydralazine can be decreased when combined with Metoprolol.
Cimetidine	Cimetidine The metabolism of Cimetidine can be decreased when combined with Metoprolol.
Gentamicin Injection	Gentamicin Injection Gentamicin may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Warfarin	Warfarin The metabolism of Warfarin can be decreased when combined with Metoprolol.
Clonazepam	Clonazepam Metoprolol may decrease the excretion rate of Clonazepam which could result in a higher serum level.
Loperamide	Loperamide The metabolism of Metoprolol can be decreased when combined with Loperamide.
Promethazine	Promethazine The metabolism of Metoprolol can be decreased when combined with Promethazine.
Meclofenamate	Meclofenamate Meclofenamic acid may decrease the antihypertensive activities of Metoprolol.
Daunorubicin	Daunorubicin The metabolism of Metoprolol can be decreased when combined with Daunorubicin.
Nitrofurantoin	Nitrofurantoin The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Nitrofurantoin.
Griseofulvin	Griseofulvin The metabolism of Metoprolol can be increased when combined with Griseofulvin.
Digoxin	Digoxin Metoprolol may increase the arrhythmogenic activities of Digoxin.
Chloroquine	Chloroquine The metabolism of Metoprolol can be decreased when combined with Chloroquine.
Quinine	Quinine The metabolism of Metoprolol can be decreased when combined with Quinine.
Ethosuximide	Ethosuximide The risk or severity of bradycardia can be increased when Metoprolol is combined with Ethosuximide.
Calcitriol	Calcitriol The metabolism of Metoprolol can be increased when combined with Calcitriol.
Triamterene	Triamterene Metoprolol may decrease the excretion rate of Triamterene which could result in a higher serum level.
Sulfinpyrazone	Sulfinpyrazone The metabolism of Metoprolol can be increased when combined with Sulfinpyrazone.
Chlorothiazide	Chlorothiazide The therapeutic efficacy of Chlorothiazide can be increased when used in combination with Metoprolol.
Chlorthalidone	Chlorthalidone Metoprolol may increase the excretion rate of Chlorthalidone which could result in a lower serum level and potentially a reduction in efficacy.
Metolazone	Metolazone Metoprolol may increase the excretion rate of Metolazone which could result in a lower serum level and potentially a reduction in efficacy.
Isosorbide	Isosorbide Isosorbide may increase the excretion rate of Metoprolol which could result in a lower serum level and potentially a reduction in efficacy.
Secobarbital	Secobarbital The serum concentration of Metoprolol can be decreased when it is combined with Secobarbital.
Desipramine	Desipramine The metabolism of Desipramine can be decreased when combined with Metoprolol.
Amitriptyline	Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Metoprolol.
Imipramine	Imipramine The metabolism of Imipramine can be decreased when combined with Metoprolol.
Probenecid	Probenecid The metabolism of Probenecid can be increased when combined with Metoprolol.
Quinidine	Quinidine Quinidine may increase the arrhythmogenic activities of Metoprolol.
Procainamide	Procainamide The metabolism of Procainamide can be decreased when combined with Metoprolol.
Isoniazid	Isoniazid The metabolism of Isoniazid can be decreased when combined with Metoprolol.
Pyrazinamide	Pyrazinamide Metoprolol may decrease the excretion rate of Pyrazinamide which could result in a higher serum level.
Rifampin	Rifampin The metabolism of Metoprolol can be increased when combined with Rifampicin.
Disopyramide	Disopyramide Disopyramide may increase the bradycardic activities of Metoprolol.
Valproic Acid	Valproic Acid The metabolism of Metoprolol can be decreased when combined with Valproic acid.
Tamoxifen	Tamoxifen The metabolism of Metoprolol can be decreased when combined with Tamoxifen.
Butabarbital	Butabarbital Butabarbital may increase the hypotensive activities of Metoprolol.
Levothyroxine	Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Metoprolol.
Liothyronine	Liothyronine The therapeutic efficacy of Liothyronine can be decreased when used in combination with Metoprolol.
Methimazole	Methimazole The excretion of Methimazole can be decreased when combined with Metoprolol.
Chlorpropamide	Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Metoprolol.
Glucagon Injection	Glucagon Injection The therapeutic efficacy of Metoprolol can be decreased when used in combination with Glucagon.
Tolbutamide	Tolbutamide The therapeutic efficacy of Tolbutamide can be increased when used in combination with Metoprolol.
Tolazamide	Tolazamide The therapeutic efficacy of Tolazamide can be increased when used in combination with Metoprolol.
Dextromethorphan	Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Metoprolol.
Niacin	Niacin The metabolism of Metoprolol can be decreased when combined with Niacin.
Baclofen	Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Metoprolol.
Clemastine	Clemastine The metabolism of Metoprolol can be decreased when combined with Clemastine.
Chlorpheniramine	Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Metoprolol.
Meclizine	Meclizine The metabolism of Meclizine can be decreased when combined with Metoprolol.
Ethambutol	Ethambutol Metoprolol may decrease the excretion rate of Ethambutol which could result in a higher serum level.
Methyclothiazide	Methyclothiazide The therapeutic efficacy of Metoprolol can be increased when used in combination with Methyclothiazide.
Dantrolene	Dantrolene The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Dantrolene.
Chlorzoxazone	Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Metoprolol.
Pyridoxine	Pyridoxine Pyridoxine may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Folic Acid	Folic Acid Folic acid may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Danazol	Danazol The metabolism of Metoprolol can be decreased when combined with Danazol.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The metabolism of Propranolol can be decreased when combined with Metoprolol.
Minoxidil	Minoxidil Metoprolol may increase the hypotensive activities of Minoxidil.
Pseudoephedrine	Pseudoephedrine The therapeutic efficacy of Metoprolol can be decreased when used in combination with Pseudoephedrine.
Nortriptyline	Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Metoprolol.
Spironolactone	Spironolactone Metoprolol may increase the excretion rate of Spironolactone which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection	Amphotericin B Injection Amphotericin B may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Mercaptopurine	Mercaptopurine The therapeutic efficacy of Mercaptopurine can be decreased when used in combination with Metoprolol.
Phytonadione	Phytonadione Metoprolol may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
Amikacin Injection	Amikacin Injection Amikacin may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Nadolol	Nadolol The metabolism of Nadolol can be decreased when combined with Metoprolol.
Allopurinol	Allopurinol Metoprolol may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Flavoxate	Flavoxate Metoprolol may decrease the excretion rate of Flavoxate which could result in a higher serum level.
Papaverine	Papaverine The risk or severity of adverse effects can be increased when Papaverine is combined with Metoprolol.
Colchicine	Colchicine The metabolism of Metoprolol can be increased when combined with Colchicine.
Cefaclor	Cefaclor Cefaclor may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Cefadroxil	Cefadroxil Cefadroxil may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Cefazolin Injection	Cefazolin Injection Cefazolin may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Cephalexin	Cephalexin Cephalexin may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Cefoxitin Injection	Cefoxitin Injection Cefoxitin may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Dacarbazine	Dacarbazine Metoprolol may decrease the excretion rate of Dacarbazine which could result in a higher serum level.
Acetazolamide	Acetazolamide The metabolism of Metoprolol can be decreased when combined with Acetazolamide.
Cefotaxime Injection	Cefotaxime Injection Cefotaxime may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Calcitonin Salmon Injection	Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Ketoconazole	Ketoconazole The metabolism of Metoprolol can be decreased when combined with Ketoconazole.
Pyrantel	Pyrantel Metoprolol may decrease the excretion rate of Pyrantel which could result in a higher serum level.
Thiotepa Injection	Thiotepa Injection The metabolism of Metoprolol can be decreased when combined with Thiotepa.
Vincristine Injection	Vincristine Injection The metabolism of Vincristine can be decreased when combined with Metoprolol.
Captopril	Captopril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Captopril.
Dipyridamole	Dipyridamole Dipyridamole may increase the bradycardic activities of Metoprolol.
Isoxsuprine	Isoxsuprine The therapeutic efficacy of Isoxsuprine can be decreased when used in combination with Metoprolol.
Vinblastine	Vinblastine The metabolism of Metoprolol can be decreased when combined with Vinblastine.
Bethanechol	Bethanechol The risk or severity of adverse effects can be increased when Metoprolol is combined with Bethanechol.
Ethacrynic Acid	Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Colistimethate Injection	Colistimethate Injection Colistimethate may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Hydroxyzine	Hydroxyzine The metabolism of Metoprolol can be decreased when combined with Hydroxyzine.
Aspirin	Aspirin Acetylsalicylic acid may decrease the antihypertensive activities of Metoprolol.
Salsalate	Salsalate Salsalate may decrease the antihypertensive activities of Metoprolol.
Alprazolam	Alprazolam Metoprolol may decrease the excretion rate of Alprazolam which could result in a higher serum level.
Temazepam	Temazepam Temazepam may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Triazolam	Triazolam Metoprolol may decrease the excretion rate of Triazolam which could result in a higher serum level.
Dicyclomine	Dicyclomine Metoprolol may decrease the excretion rate of Dicyclomine which could result in a higher serum level.
Hyoscyamine	Hyoscyamine Metoprolol may increase the arrhythmogenic activities of Hyoscyamine.
Propantheline	Propantheline Metoprolol may decrease the excretion rate of Propantheline which could result in a higher serum level.
Trimethoprim	Trimethoprim Metoprolol may decrease the excretion rate of Trimethoprim which could result in a higher serum level.
Diltiazem	Diltiazem The metabolism of Metoprolol can be decreased when combined with Diltiazem.
Nifedipine	Nifedipine The risk or severity of congestive heart failure and hypotension can be increased when Nifedipine is combined with Metoprolol.
Timolol	Timolol The risk or severity of adverse effects can be increased when Timolol is combined with Metoprolol.
Verapamil	Verapamil The risk or severity of adverse effects can be increased when Metoprolol is combined with Verapamil.
Atenolol	Atenolol The metabolism of Atenolol can be decreased when combined with Metoprolol.
Pindolol	Pindolol The metabolism of Pindolol can be decreased when combined with Metoprolol.
Cisplatin Injection	Cisplatin Injection The serum concentration of Cisplatin can be increased when it is combined with Metoprolol.
Diflunisal	Diflunisal Diflunisal may decrease the antihypertensive activities of Metoprolol.
Piroxicam	Piroxicam Piroxicam may decrease the antihypertensive activities of Metoprolol.
Bumetanide	Bumetanide Metoprolol may increase the excretion rate of Bumetanide which could result in a lower serum level and potentially a reduction in efficacy.
Etoposide	Etoposide The metabolism of Metoprolol can be decreased when combined with Etoposide.
Glyburide	Glyburide The therapeutic efficacy of Glyburide can be increased when used in combination with Metoprolol.
Glipizide	Glipizide The therapeutic efficacy of Glipizide can be increased when used in combination with Metoprolol.
Indapamide	Indapamide The therapeutic efficacy of Indapamide can be increased when used in combination with Metoprolol.
Amoxicillin	Amoxicillin Metoprolol may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Dicloxacillin	Dicloxacillin The metabolism of Metoprolol can be increased when combined with Dicloxacillin.
Nafcillin Injection	Nafcillin Injection The metabolism of Metoprolol can be increased when combined with Nafcillin.
Oxacillin Injection	Oxacillin Injection Metoprolol may decrease the excretion rate of Oxacillin which could result in a higher serum level.
Pentoxifylline	Pentoxifylline Pentoxifylline may increase the hypotensive activities of Metoprolol.
Pentamidine Injection	Pentamidine Injection The metabolism of Metoprolol can be decreased when combined with Pentamidine.
Ceftriaxone Injection	Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Labetalol	Labetalol The metabolism of Labetalol can be decreased when combined with Metoprolol.
Auranofin	Auranofin Metoprolol may decrease the excretion rate of Auranofin which could result in a higher serum level.
Leuprolide Injection	Leuprolide Injection Leuprolide may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Gemfibrozil	Gemfibrozil Metoprolol may decrease the excretion rate of Gemfibrozil which could result in a higher serum level.
Guanabenz	Guanabenz The therapeutic efficacy of Guanabenz can be decreased when used in combination with Metoprolol.
Dipivefrin Ophthalmic	Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Ceftazidime Injection	Ceftazidime Injection Ceftazidime may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Ketoprofen	Ketoprofen Ketoprofen may decrease the antihypertensive activities of Metoprolol.
Cefotetan Injection	Cefotetan Injection Cefotetan may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Pimozide	Pimozide The metabolism of Pimozide can be decreased when combined with Metoprolol.
Enalapril	Enalapril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Enalapril.
Flurbiprofen	Flurbiprofen Flurbiprofen may decrease the antihypertensive activities of Metoprolol.
Amiodarone	Amiodarone The therapeutic efficacy of Metoprolol can be increased when used in combination with Amiodarone.
Aztreonam Injection	Aztreonam Injection Metoprolol may decrease the excretion rate of Aztreonam which could result in a higher serum level.
Buspirone	Buspirone The metabolism of Buspirone can be decreased when combined with Metoprolol.
Lovastatin	Lovastatin The metabolism of Metoprolol can be decreased when combined with Lovastatin.
Ciprofloxacin	Ciprofloxacin The metabolism of Ciprofloxacin can be decreased when combined with Metoprolol.
Mesalamine	Mesalamine Mesalazine may decrease the antihypertensive activities of Metoprolol.
Diclofenac	Diclofenac Diclofenac may decrease the antihypertensive activities of Metoprolol.
Fluoxetine	Fluoxetine The serum concentration of Metoprolol can be increased when it is combined with Fluoxetine.
Nimodipine	Nimodipine The risk or severity of bradycardia can be increased when Nimodipine is combined with Metoprolol.
Clozapine	Clozapine The metabolism of Clozapine can be decreased when combined with Metoprolol.
Estazolam	Estazolam Metoprolol may decrease the excretion rate of Estazolam which could result in a higher serum level.
Idarubicin	Idarubicin The metabolism of Idarubicin can be decreased when combined with Metoprolol.
Didanosine	Didanosine Metoprolol may decrease the excretion rate of Didanosine which could result in a higher serum level.
Pentostatin Injection	Pentostatin Injection Metoprolol may decrease the excretion rate of Pentostatin which could result in a higher serum level.
Clarithromycin	Clarithromycin The metabolism of Metoprolol can be decreased when combined with Clarithromycin.
Benazepril	Benazepril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Benazepril.
Etodolac	Etodolac Etodolac may decrease the antihypertensive activities of Metoprolol.
Felodipine	Felodipine The risk or severity of bradycardia can be increased when Metoprolol is combined with Felodipine.
Fosinopril	Fosinopril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Fosinopril.
Nabumetone	Nabumetone Nabumetone may decrease the antihypertensive activities of Metoprolol.
Quinapril	Quinapril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Quinapril.
Ramipril	Ramipril Ramipril may increase the hypotensive activities of Metoprolol.
Simvastatin	Simvastatin The metabolism of Simvastatin can be decreased when combined with Metoprolol.
Amlodipine	Amlodipine The risk or severity of bradycardia can be increased when Amlodipine is combined with Metoprolol.
Teniposide Injection	Teniposide Injection The metabolism of Metoprolol can be decreased when combined with Teniposide.
Itraconazole	Itraconazole The metabolism of Metoprolol can be decreased when combined with Itraconazole.
Lisinopril	Lisinopril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Lisinopril.
Oxaprozin	Oxaprozin Oxaprozin may decrease the antihypertensive activities of Metoprolol.
Rifabutin	Rifabutin The metabolism of Metoprolol can be increased when combined with Rifabutin.
Sotalol	Sotalol The metabolism of Sotalol can be decreased when combined with Metoprolol.
Bisoprolol	Bisoprolol The risk or severity of adverse effects can be increased when Bisoprolol is combined with Metoprolol.
Zolpidem	Zolpidem The metabolism of Zolpidem can be decreased when combined with Metoprolol.
Doxazosin	Doxazosin The metabolism of Doxazosin can be decreased when combined with Metoprolol.
Terazosin	Terazosin Metoprolol may increase the orthostatic hypotensive activities of Terazosin.
Isradipine	Isradipine The risk or severity of bradycardia can be increased when Isradipine is combined with Metoprolol.
Omeprazole	Omeprazole The metabolism of Metoprolol can be increased when combined with Omeprazole.
Cisapride	Cisapride The metabolism of Cisapride can be decreased when combined with Metoprolol.
Fluvastatin	Fluvastatin The metabolism of Metoprolol can be decreased when combined with Fluvastatin.
Venlafaxine	Venlafaxine The serum concentration of Venlafaxine can be increased when it is combined with Metoprolol.
Nizatidine	Nizatidine Nizatidine may increase the bradycardic activities of Metoprolol.
Famciclovir	Famciclovir The metabolism of Famciclovir can be decreased when combined with Metoprolol.
Fluvoxamine	Fluvoxamine The metabolism of Metoprolol can be decreased when combined with Fluvoxamine.
Nefazodone	Nefazodone The metabolism of Metoprolol can be decreased when combined with Nefazodone.
Lamotrigine	Lamotrigine The risk or severity of bradycardia can be increased when Metoprolol is combined with Lamotrigine.
Losartan	Losartan Losartan may increase the arrhythmogenic activities of Metoprolol.
Valacyclovir	Valacyclovir Valaciclovir may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Tramadol	Tramadol The metabolism of Metoprolol can be decreased when combined with Tramadol.
Vinorelbine Injection	Vinorelbine Injection The metabolism of Metoprolol can be decreased when combined with Vinorelbine.
Carboplatin Injection	Carboplatin Injection Carboplatin may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Moexipril	Moexipril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Moexipril.
Lansoprazole	Lansoprazole The metabolism of Metoprolol can be increased when combined with Lansoprazole.
Ifosfamide Injection	Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Metoprolol.
Nicardipine	Nicardipine The metabolism of Nicardipine can be decreased when combined with Metoprolol.
Bupropion	Bupropion The metabolism of Metoprolol can be decreased when combined with Bupropion.
Ticlopidine	Ticlopidine The metabolism of Metoprolol can be decreased when combined with Ticlopidine.
Saquinavir	Saquinavir The metabolism of Saquinavir can be decreased when combined with Metoprolol.
Metformin	Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Metoprolol.
Dalteparin Injection	Dalteparin Injection The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Dalteparin.
Nisoldipine	Nisoldipine The risk or severity of bradycardia can be increased when Metoprolol is combined with Nisoldipine.
Lamivudine	Lamivudine The serum concentration of Lamivudine can be increased when it is combined with Metoprolol.
Amifostine Injection	Amifostine Injection Metoprolol may increase the hypotensive activities of Amifostine.
Acarbose	Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Metoprolol.
Glimepiride	Glimepiride Metoprolol may increase the arrhythmogenic activities of Glimepiride.
Gemcitabine Injection	Gemcitabine Injection Metoprolol may decrease the excretion rate of Gemcitabine which could result in a higher serum level.
Ritonavir	Ritonavir The serum concentration of Metoprolol can be increased when it is combined with Ritonavir.
Docetaxel Injection	Docetaxel Injection The metabolism of Metoprolol can be decreased when combined with Docetaxel.
Cidofovir Injection	Cidofovir Injection Cidofovir may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Meropenem Injection	Meropenem Injection Metoprolol may decrease the excretion rate of Meropenem which could result in a higher serum level.
Clomipramine	Clomipramine The metabolism of Clomipramine can be decreased when combined with Metoprolol.
Zafirlukast	Zafirlukast The metabolism of Metoprolol can be decreased when combined with Zafirlukast.
Fosfomycin	Fosfomycin Metoprolol may decrease the excretion rate of Fosfomycin which could result in a higher serum level.
Mirtazapine	Mirtazapine The metabolism of Mirtazapine can be decreased when combined with Metoprolol.
Trandolapril	Trandolapril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Trandolapril.
Topiramate	Topiramate The metabolism of Metoprolol can be increased when combined with Topiramate.
Valsartan	Valsartan The risk or severity of hyperkalemia can be increased when Valsartan is combined with Metoprolol.
Insulin Lispro Injection	Insulin Lispro Injection The therapeutic efficacy of Insulin lispro can be increased when used in combination with Metoprolol.
Pramipexole	Pramipexole The serum concentration of Pramipexole can be increased when it is combined with Metoprolol.
Donepezil	Donepezil The metabolism of Donepezil can be decreased when combined with Metoprolol.
Nelfinavir	Nelfinavir The metabolism of Metoprolol can be decreased when combined with Nelfinavir.
Azithromycin	Azithromycin The metabolism of Metoprolol can be decreased when combined with Azithromycin.
Carvedilol	Carvedilol The metabolism of Carvedilol can be decreased when combined with Metoprolol.
Nilutamide	Nilutamide Metoprolol may decrease the excretion rate of Nilutamide which could result in a higher serum level.
Flutamide	Flutamide Metoprolol may decrease the excretion rate of Flutamide which could result in a higher serum level.
Selegiline	Selegiline The metabolism of Metoprolol can be decreased when combined with Selegiline.
Bicalutamide	Bicalutamide The metabolism of Metoprolol can be decreased when combined with Bicalutamide.
Sertraline	Sertraline The metabolism of Metoprolol can be decreased when combined with Sertraline.
Propafenone	Propafenone The risk or severity of adverse effects can be increased when Propafenone is combined with Metoprolol.
Raloxifene	Raloxifene The metabolism of Metoprolol can be decreased when combined with Raloxifene.
Irbesartan	Irbesartan The metabolism of Irbesartan can be decreased when combined with Metoprolol.
Tamsulosin	Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Metoprolol.
Ropinirole	Ropinirole The risk or severity of adverse effects can be increased when Ropinirole is combined with Metoprolol.
Finasteride	Finasteride Finasteride may decrease the antihypertensive activities of Metoprolol.
Quetiapine	Quetiapine Metoprolol may increase the hypotensive activities of Quetiapine.
Cefepime Injection	Cefepime Injection Cefepime may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Cefprozil	Cefprozil Cefprozil may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Cefpodoxime	Cefpodoxime Cefpodoxime may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Cetirizine	Cetirizine Metoprolol may decrease the excretion rate of Cetirizine which could result in a higher serum level.
Paroxetine	Paroxetine The metabolism of Metoprolol can be decreased when combined with Paroxetine.
Tolcapone	Tolcapone Metoprolol may decrease the excretion rate of Tolcapone which could result in a higher serum level.
Citalopram	Citalopram The metabolism of Metoprolol can be decreased when combined with Citalopram.
Capecitabine	Capecitabine Metoprolol may decrease the excretion rate of Capecitabine which could result in a higher serum level.
Efavirenz	Efavirenz The metabolism of Metoprolol can be decreased when combined with Efavirenz.
Abacavir	Abacavir Metoprolol may decrease the excretion rate of Abacavir which could result in a higher serum level.
Sildenafil	Sildenafil The metabolism of Sildenafil can be decreased when combined with Metoprolol.
Pioglitazone	Pioglitazone The therapeutic efficacy of Metoprolol can be increased when used in combination with Pioglitazone.
Celecoxib	Celecoxib Celecoxib may decrease the antihypertensive activities of Metoprolol.
Rosiglitazone	Rosiglitazone The therapeutic efficacy of Metoprolol can be increased when used in combination with Rosiglitazone.
Tolterodine	Tolterodine The metabolism of Tolterodine can be decreased when combined with Metoprolol.
Thalidomide	Thalidomide The risk or severity of adverse effects can be increased when Thalidomide is combined with Metoprolol.
Oseltamivir	Oseltamivir Oseltamivir may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Balsalazide	Balsalazide Balsalazide may decrease the antihypertensive activities of Metoprolol.
Nateglinide	Nateglinide The metabolism of Nateglinide can be decreased when combined with Metoprolol.
Galantamine	Galantamine The metabolism of Galantamine can be decreased when combined with Metoprolol.
Rabeprazole	Rabeprazole The metabolism of Rabeprazole can be decreased when combined with Metoprolol.
Terbinafine	Terbinafine The metabolism of Metoprolol can be decreased when combined with Terbinafine.

* This branded product is no longer on the market. Generic alternatives may be available.

Metoprolol

On this page