Metoprolol
Generic name: Pronounced as (me toe' proe lole)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 09/15/2017
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Brand names of combination products
- Drug interactions
IMPORTANT WARNING
Do not stop taking metoprolol without talking to your doctor. Suddenly stopping metoprolol may cause chest pain or heart attack. Your doctor will probably decrease your dose gradually.
Why is this medication prescribed?
Metoprolol is used alone or in combination with other medications to treat high blood pressure. It also is used to prevent angina (chest pain) and to improve survival after a heart attack. Metoprolol also is used in combination with other medications to treat heart failure. Metoprolol is in a class of medications called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.
High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
How should this medicine be used?
Metoprolol comes as a tablet and an extended-release (long-acting) tablet to take by mouth. The regular tablet is usually taken once or twice a day with meals or immediately after meals. The extended-release tablet is usually taken once a day. To help you remember to take metoprolol, take it around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take metoprolol exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
The extended-release tablet may be split. Swallow the whole or half tablets whole; do not chew or crush them.
Your doctor may start you on a low dose of metoprolol and gradually increase your dose.
Metoprolol controls high blood pressure and angina but does not cure them. Metoprolol extended-release tablets control heart failure but does not cure it. It may take a few weeks before you feel the full benefit of metoprolol. Continue to take metoprolol even if you feel well.
Other uses for this medicine
Metoprolol is also used sometimes to prevent migraine headaches and to treat irregular heartbeat and movement disorders caused by medications for mental illness. Talk to your doctor about the possible risks of using this medication for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking metoprolol,
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tell your doctor and pharmacist if you are allergic to metoprolol, acebutolol (Sectral), atenolol (Tenormin, in Tenoretic), betaxolol, bisoprolol (Zebeta, in Ziac), carvedilol (Coreg, Coreg CR), esmolol (Brevibloc), labetalol, nadolol (Corgard, in Corzide), pindolol, propranolol (Inderal, Inderal LA, Innopran XL, in Inderide), sotalol (Betapace, Betapace AF, Sorine), timolol, any other medications, or any of the ingredients in metoprolol tablets. Ask your pharmacist for a list of the ingredients.
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tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: bupropion (Aplenzin, Forfivo, Wellbutrin, Zyban), cimetidine, clonidine (Catapres), diphenhydramine (Benadryl), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), hydroxychloroquine, paroxetine (Brisdelle, Paxil, Pexeva), propafenone (Rythmol), quinidine, ranitidine (Zantac), reserpine, ritonavir (Norvir, in Kaletra), terbinafine (Lamisil), and thioridazine. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
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tell your doctor if you have a slow heart rate, heart failure, problems with blood circulation, or pheochromocytoma (a tumor that develops on a gland near the kidneys and may cause high blood pressure and fast heartbeat). Your doctor may tell you not to take metoprolol.
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tell your doctor if you have or have ever had asthma or other lung diseases; heart or liver disease; diabetes; severe allergies; or hyperthyroidism (an overactive thyroid gland).
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tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking metoprolol, call your doctor.
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if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking metoprolol.
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you should know that metoprolol may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
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remember that alcohol can add to the drowsiness caused by this medication.
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you should know that if you have allergic reactions to different substances, your reactions may be worse while you are using metoprolol, and your allergic reactions may not respond to the usual doses of injectable epinephrine.
What special dietary instructions should I follow?
If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Metoprolol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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dizziness or lightheadedness
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tiredness
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depression
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nausea
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dry mouth
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stomach pain
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vomiting
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gas or bloating
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heartburn
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constipation
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rash or itching
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cold hands and feet
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runny nose
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Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
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shortness of breath
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wheezing
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swelling of the hands, feet, ankles, or lower legs
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weight gain
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fainting
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rapid, pounding, or irregular heartbeat
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Metoprolol may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include the following:
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dizziness
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fainting
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difficulty breathing or swallowing
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swelling of the hands, feet, ankles, or lower legs
What OTHER INFORMATION should I know?
Keep all appointments with your doctor. Your blood pressure should be checked regularly to determine your response to metoprolol. Your doctor may ask you to check your pulse (heart rate). Ask your pharmacist or doctor to teach you how to take your pulse. If your pulse is faster or slower than it should be, call your doctor.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Repaglinide | Repaglinide The therapeutic efficacy of Repaglinide can be increased when used in combination with Metoprolol. |
Insulin Glargine (rDNA origin) Injection | Insulin Glargine (rDNA origin) Injection The therapeutic efficacy of Insulin glargine can be increased when used in combination with Metoprolol. |
Delavirdine | Delavirdine The metabolism of Metoprolol can be decreased when combined with Delavirdine. |
Nevirapine | Nevirapine The metabolism of Metoprolol can be decreased when combined with Nevirapine. |
Dolasetron | Dolasetron The metabolism of Dolasetron can be decreased when combined with Metoprolol. |
Aminophylline | Aminophylline The metabolism of Aminophylline can be decreased when combined with Metoprolol. |
Calcium Carbonate | Calcium Carbonate The therapeutic efficacy of Metoprolol can be decreased when used in combination with Calcium carbonate. |
Candesartan | Candesartan The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Candesartan. |
Cilostazol | Cilostazol The metabolism of Cilostazol can be decreased when combined with Metoprolol. |
Erythromycin and Sulfisoxazole | Erythromycin and Sulfisoxazole The metabolism of Metoprolol can be decreased when combined with Erythromycin. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) Metoprolol may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level. |
Fenofibrate | Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Metoprolol. |
Guanfacine | Guanfacine The therapeutic efficacy of Guanfacine can be decreased when used in combination with Metoprolol. |
Magnesium Hydroxide | Magnesium Hydroxide Metoprolol may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level. |
Methylergonovine | Methylergonovine Metoprolol may increase the vasoconstricting activities of Methylergometrine. |
Miglitol | Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Metoprolol. |
Mycophenolate | Mycophenolate Metoprolol may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level. |
Naratriptan | Naratriptan Naratriptan may decrease the antihypertensive activities of Metoprolol. |
Olsalazine | Olsalazine Olsalazine may decrease the antihypertensive activities of Metoprolol. |
Paregoric | Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Metoprolol. |
Penbutolol | Penbutolol The metabolism of Acebutolol can be decreased when combined with Metoprolol. |
Potassium | Potassium Potassium may increase the excretion rate of Metoprolol which could result in a lower serum level and potentially a reduction in efficacy. |
Prednisone | Prednisone Metoprolol may decrease the excretion rate of Prednisone which could result in a higher serum level. |
Ranitidine | Ranitidine The serum concentration of Ranitidine can be increased when it is combined with Metoprolol. |
Reserpine | Reserpine Reserpine may increase the hypotensive activities of Metoprolol. |
Rizatriptan | Rizatriptan Metoprolol may decrease the excretion rate of Rizatriptan which could result in a higher serum level. |
Sumatriptan | Sumatriptan Sumatriptan may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Tacrolimus | Tacrolimus The metabolism of Tacrolimus can be decreased when combined with Metoprolol. |
Tizanidine | Tizanidine The therapeutic efficacy of Tizanidine can be decreased when used in combination with Metoprolol. |
Triamcinolone | Triamcinolone The metabolism of Metoprolol can be increased when combined with Triamcinolone. |
Zolmitriptan | Zolmitriptan Zolmitriptan may decrease the antihypertensive activities of Metoprolol. |
Ampicillin Injection | Ampicillin Injection Metoprolol may decrease the excretion rate of Ampicillin which could result in a higher serum level. |
Doxycycline Injection | Doxycycline Injection The metabolism of Metoprolol can be decreased when combined with Doxycycline. |
Fluconazole Injection | Fluconazole Injection The metabolism of Metoprolol can be decreased when combined with Fluconazole. |
Foscarnet Injection | Foscarnet Injection Foscarnet may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Hydromorphone Injection | Hydromorphone Injection Metoprolol may decrease the excretion rate of Hydromorphone which could result in a higher serum level. |
Levofloxacin Injection | Levofloxacin Injection Metoprolol may decrease the excretion rate of Levofloxacin which could result in a higher serum level. |
Meperidine Injection | Meperidine Injection The metabolism of Meperidine can be decreased when combined with Metoprolol. |
Methylprednisolone Injection | Methylprednisolone Injection The metabolism of Metoprolol can be increased when combined with Methylprednisolone. |
Metoclopramide Injection | Metoclopramide Injection The metabolism of Metoclopramide can be decreased when combined with Metoprolol. |
Metronidazole Injection | Metronidazole Injection The metabolism of Metoprolol can be decreased when combined with Metronidazole. |
Morphine Injection | Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Metoprolol. |
Pamidronate Injection | Pamidronate Injection Pamidronic acid may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Vancomycin Injection | Vancomycin Injection Metoprolol may decrease the excretion rate of Vancomycin which could result in a higher serum level. |
Altretamine | Altretamine The metabolism of Metoprolol can be decreased when combined with Amphetamine. |
Cefuroxime | Cefuroxime Cefuroxime may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Cyclosporine | Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Metoprolol. |
Ondansetron | Ondansetron The metabolism of Ondansetron can be decreased when combined with Metoprolol. |
Enoxaparin Injection | Enoxaparin Injection The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Enoxaparin. |
Torsemide | Torsemide Torasemide may increase the excretion rate of Metoprolol which could result in a lower serum level and potentially a reduction in efficacy. |
Olanzapine | Olanzapine The metabolism of Olanzapine can be decreased when combined with Metoprolol. |
Dofetilide | Dofetilide Metoprolol may increase the arrhythmogenic activities of Dofetilide. |
Entacapone | Entacapone The metabolism of Metoprolol can be decreased when combined with Entacapone. |
Eprosartan | Eprosartan The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Eprosartan. |
Hydroxychloroquine | Hydroxychloroquine The metabolism of Metoprolol can be decreased when combined with Hydroxychloroquine. |
Meloxicam | Meloxicam Meloxicam may decrease the antihypertensive activities of Metoprolol. |
Orlistat | Orlistat The metabolism of Metoprolol can be increased when combined with Orlistat. |
Oxcarbazepine | Oxcarbazepine The metabolism of Metoprolol can be increased when combined with Oxcarbazepine. |
Pantoprazole | Pantoprazole Pantoprazole may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Telmisartan | Telmisartan The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Telmisartan. |
Temozolomide | Temozolomide Metoprolol may decrease the excretion rate of Temozolomide which could result in a higher serum level. |
Zaleplon | Zaleplon Metoprolol may decrease the excretion rate of Zaleplon which could result in a higher serum level. |
Anakinra | Anakinra The metabolism of Metoprolol can be increased when combined with Anakinra. |
Linezolid | Linezolid Linezolid may increase the hypotensive activities of Metoprolol. |
Rivastigmine | Rivastigmine Metoprolol may increase the bradycardic activities of Rivastigmine. |
Trimipramine | Trimipramine The metabolism of Trimipramine can be decreased when combined with Metoprolol. |
Etanercept Injection | Etanercept Injection The metabolism of Metoprolol can be increased when combined with Etanercept. |
Modafinil | Modafinil The metabolism of Metoprolol can be increased when combined with Modafinil. |
Perindopril | Perindopril Metoprolol may increase the hypotensive activities of Perindopril. |
Tenofovir | Tenofovir Tenofovir may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Choline Magnesium Trisalicylate | Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the antihypertensive activities of Metoprolol. |
Sirolimus | Sirolimus The metabolism of Sirolimus can be decreased when combined with Metoprolol. |
Dutasteride | Dutasteride Dutasteride may decrease the antihypertensive activities of Metoprolol. |
Epinephrine Injection | Epinephrine Injection The therapeutic efficacy of Epinephrine can be decreased when used in combination with Metoprolol. |
Eplerenone | Eplerenone Metoprolol may increase the excretion rate of Eplerenone which could result in a lower serum level and potentially a reduction in efficacy. |
Escitalopram | Escitalopram The serum concentration of Escitalopram can be increased when it is combined with Metoprolol. |
Olmesartan | Olmesartan The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Olmesartan. |
Zonisamide | Zonisamide The risk or severity of bradycardia can be increased when Zonisamide is combined with Metoprolol. |
Adalimumab Injection | Adalimumab Injection The metabolism of Metoprolol can be increased when combined with Adalimumab. |
Aripiprazole | Aripiprazole The metabolism of Metoprolol can be decreased when combined with Aripiprazole. |
Atomoxetine | Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Metoprolol. |
Dexmethylphenidate | Dexmethylphenidate Dexmethylphenidate may decrease the antihypertensive activities of Metoprolol. |
Atazanavir | Atazanavir The metabolism of Metoprolol can be decreased when combined with Atazanavir. |
Almotriptan | Almotriptan The metabolism of Almotriptan can be decreased when combined with Metoprolol. |
Eletriptan | Eletriptan The metabolism of Eletriptan can be decreased when combined with Metoprolol. |
Mefloquine | Mefloquine The risk or severity of QTc prolongation can be decreased when Mefloquine is combined with Metoprolol. |
Rosuvastatin | Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Metoprolol. |
Vardenafil | Vardenafil Vardenafil may increase the antihypertensive activities of Metoprolol. |
Alfuzosin | Alfuzosin Alfuzosin may increase the hypotensive activities of Metoprolol. |
Aprepitant | Aprepitant The metabolism of Metoprolol can be decreased when combined with Aprepitant. |
Emtricitabine | Emtricitabine Metoprolol may decrease the excretion rate of Emtricitabine which could result in a higher serum level. |
Memantine | Memantine Memantine may increase the bradycardic activities of Metoprolol. |
Tegaserod | Tegaserod The metabolism of Tegaserod can be decreased when combined with Metoprolol. |
Tadalafil | Tadalafil Metoprolol may increase the antihypertensive activities of Tadalafil. |
Frovatriptan | Frovatriptan Frovatriptan may decrease the antihypertensive activities of Metoprolol. |
Progesterone | Progesterone The metabolism of Metoprolol can be decreased when combined with Progesterone. |
Apomorphine Injection | Apomorphine Injection The risk or severity of adverse effects can be increased when Apomorphine is combined with Metoprolol. |
Infliximab Injection | Infliximab Injection The metabolism of Metoprolol can be increased when combined with Infliximab. |
Protriptyline | Protriptyline The metabolism of Protriptyline can be decreased when combined with Metoprolol. |
Rifaximin | Rifaximin The metabolism of Metoprolol can be increased when combined with Rifaximin. |
Duloxetine | Duloxetine The risk or severity of orthostatic hypotension and syncope can be increased when Metoprolol is combined with Duloxetine. |
Norethindrone | Norethindrone The metabolism of Norethisterone can be decreased when combined with Metoprolol. |
Tinidazole | Tinidazole Metoprolol may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
Trospium | Trospium The metabolism of Metoprolol can be decreased when combined with Trospium. |
Bosentan | Bosentan The metabolism of Metoprolol can be increased when combined with Bosentan. |
Cefditoren | Cefditoren Metoprolol may decrease the excretion rate of Cefdinir which could result in a higher serum level. |
Cinacalcet | Cinacalcet The metabolism of Metoprolol can be decreased when combined with Cinacalcet. |
Cyanocobalamin Injection | Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Erlotinib | Erlotinib The metabolism of Metoprolol can be decreased when combined with Erlotinib. |
Eszopiclone | Eszopiclone Metoprolol may decrease the excretion rate of Eszopiclone which could result in a higher serum level. |
Ganciclovir | Ganciclovir Metoprolol may decrease the excretion rate of Ganciclovir which could result in a higher serum level. |
Insulin Aspart (rDNA Origin) Injection | Insulin Aspart (rDNA Origin) Injection The therapeutic efficacy of Insulin aspart can be increased when used in combination with Metoprolol. |
Ribavirin | Ribavirin Metoprolol may decrease the excretion rate of Ribavirin which could result in a higher serum level. |
Solifenacin | Solifenacin The metabolism of Solifenacin can be decreased when combined with Metoprolol. |
Valganciclovir | Valganciclovir Metoprolol may decrease the excretion rate of Valganciclovir which could result in a higher serum level. |
Voriconazole | Voriconazole The metabolism of Metoprolol can be decreased when combined with Voriconazole. |
Adefovir | Adefovir Adefovir may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Dextroamphetamine | Dextroamphetamine The metabolism of Metoprolol can be decreased when combined with Amphetamine. |
Peginterferon Alfa-2b (PEG-Intron) | Peginterferon Alfa-2b (PEG-Intron) The metabolism of Metoprolol can be decreased when combined with Peginterferon alfa-2b. |
Pramlintide Injection | Pramlintide Injection The therapeutic efficacy of Pramlintide can be increased when used in combination with Metoprolol. |
Exenatide Injection | Exenatide Injection The therapeutic efficacy of Exenatide can be increased when used in combination with Metoprolol. |
Isocarboxazid | Isocarboxazid Isocarboxazid may increase the hypotensive activities of Metoprolol. |
Ramelteon | Ramelteon Metoprolol may decrease the excretion rate of Ramelteon which could result in a higher serum level. |
Darifenacin | Darifenacin The metabolism of Darifenacin can be decreased when combined with Metoprolol. |
Fentanyl | Fentanyl Fentanyl may decrease the antihypertensive activities of Metoprolol. |
Pregabalin | Pregabalin Pregabalin may increase the arrhythmogenic activities of Metoprolol. |
Deferasirox | Deferasirox The metabolism of Metoprolol can be increased when combined with Deferasirox. |
Phenylephrine | Phenylephrine The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Metoprolol. |
Tipranavir | Tipranavir The metabolism of Tipranavir can be decreased when combined with Metoprolol. |
Felbamate | Felbamate The metabolism of Metoprolol can be increased when combined with Felbamate. |
Insulin Detemir (rDNA Origin) Injection | Insulin Detemir (rDNA Origin) Injection The therapeutic efficacy of Insulin detemir can be increased when used in combination with Metoprolol. |
Ranolazine | Ranolazine The serum concentration of Metoprolol can be increased when it is combined with Ranolazine. |
Abatacept Injection | Abatacept Injection The metabolism of Metoprolol can be increased when combined with Abatacept. |
Rasagiline | Rasagiline Rasagiline may increase the hypotensive activities of Metoprolol. |
Imatinib | Imatinib The metabolism of Metoprolol can be decreased when combined with Imatinib. |
Sitagliptin | Sitagliptin The therapeutic efficacy of Sitagliptin can be increased when used in combination with Metoprolol. |
Varenicline | Varenicline The excretion of Varenicline can be decreased when combined with Metoprolol. |
Gefitinib | Gefitinib The metabolism of Metoprolol can be decreased when combined with Gefitinib. |
Albuterol | Albuterol The therapeutic efficacy of Salbutamol can be decreased when used in combination with Metoprolol. |
Paliperidone | Paliperidone The metabolism of Metoprolol can be decreased when combined with Paliperidone. |
Bortezomib | Bortezomib The metabolism of Bortezomib can be decreased when combined with Metoprolol. |
Clofarabine Injection | Clofarabine Injection The serum concentration of Clofarabine can be increased when it is combined with Metoprolol. |
Insulin Glulisine (rDNA origin) Injection | Insulin Glulisine (rDNA origin) Injection The therapeutic efficacy of Insulin glulisine can be increased when used in combination with Metoprolol. |
Lubiprostone | Lubiprostone Metoprolol may decrease the excretion rate of Lubiprostone which could result in a higher serum level. |
Oxaliplatin Injection | Oxaliplatin Injection The serum concentration of Oxaliplatin can be increased when it is combined with Metoprolol. |
Posaconazole | Posaconazole The metabolism of Metoprolol can be decreased when combined with Posaconazole. |
Primaquine | Primaquine The metabolism of Metoprolol can be decreased when combined with Primaquine. |
Rituximab Injection | Rituximab Injection Metoprolol may increase the hypotensive activities of Rituximab. |
Aliskiren | Aliskiren The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Aliskiren. |
Darunavir | Darunavir The metabolism of Darunavir can be decreased when combined with Metoprolol. |
Pemetrexed Injection | Pemetrexed Injection Metoprolol may decrease the excretion rate of Pemetrexed which could result in a higher serum level. |
Lisdexamfetamine | Lisdexamfetamine The metabolism of Metoprolol can be decreased when combined with Lisdexamfetamine. |
Nabilone | Nabilone The risk or severity of adverse effects can be increased when Nabilone is combined with Metoprolol. |
Sorafenib | Sorafenib The metabolism of Metoprolol can be decreased when combined with Sorafenib. |
Sunitinib | Sunitinib The therapeutic efficacy of Metoprolol can be increased when used in combination with Sunitinib. |
Lapatinib | Lapatinib The metabolism of Metoprolol can be decreased when combined with Lapatinib. |
Levocetirizine | Levocetirizine Metoprolol may decrease the excretion rate of Levocetirizine which could result in a higher serum level. |
Pegaptanib Injection | Pegaptanib Injection Metoprolol may decrease the excretion rate of Pegaptanib which could result in a higher serum level. |
Dasatinib | Dasatinib The metabolism of Dasatinib can be decreased when combined with Metoprolol. |
Mexiletine | Mexiletine The metabolism of Mexiletine can be decreased when combined with Metoprolol. |
Armodafinil | Armodafinil The metabolism of Metoprolol can be increased when combined with Armodafinil. |
Azacitidine Injection | Azacitidine Injection Metoprolol may decrease the excretion rate of Azacitidine which could result in a higher serum level. |
Ivermectin | Ivermectin The metabolism of Metoprolol can be increased when combined with Ivermectin. |
Temsirolimus | Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Metoprolol. |
Lenalidomide | Lenalidomide Metoprolol may decrease the excretion rate of Lenalidomide which could result in a higher serum level. |
Nilotinib | Nilotinib The metabolism of Metoprolol can be decreased when combined with Nilotinib. |
Bexarotene | Bexarotene The metabolism of Metoprolol can be increased when combined with Bexarotene. |
Budesonide | Budesonide The metabolism of Metoprolol can be increased when combined with Budesonide. |
Chloramphenicol Injection | Chloramphenicol Injection The metabolism of Metoprolol can be decreased when combined with Chloramphenicol. |
Desmopressin | Desmopressin Desmopressin may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Betaine | Betaine Glycine betaine may increase the bradycardic activities of Metoprolol. |
Doripenem Injection | Doripenem Injection Metoprolol may decrease the excretion rate of Doripenem which could result in a higher serum level. |
Etravirine | Etravirine The metabolism of Metoprolol can be increased when combined with Etravirine. |
Arsenic Trioxide Injection | Arsenic Trioxide Injection Metoprolol may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level. |
Mitoxantrone Injection | Mitoxantrone Injection The metabolism of Metoprolol can be decreased when combined with Mitoxantrone. |
Desvenlafaxine | Desvenlafaxine The serum concentration of Metoprolol can be increased when it is combined with Desvenlafaxine. |
Cevimeline | Cevimeline The metabolism of Metoprolol can be decreased when combined with Cevimeline. |
Nebivolol | Nebivolol The metabolism of Nebivolol can be decreased when combined with Metoprolol. |
Tretinoin | Tretinoin The risk or severity of adverse effects can be increased when Tretinoin is combined with Metoprolol. |
Pilocarpine | Pilocarpine The metabolism of Metoprolol can be decreased when combined with Pilocarpine. |
Flecainide | Flecainide The metabolism of Flecainide can be decreased when combined with Metoprolol. |
Certolizumab Injection | Certolizumab Injection The metabolism of Metoprolol can be increased when combined with Certolizumab pegol. |
Ixabepilone Injection | Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Metoprolol. |
Irinotecan Injection | Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Metoprolol. |
Daptomycin Injection | Daptomycin Injection Daptomycin may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Mitotane | Mitotane The metabolism of Metoprolol can be increased when combined with Mitotane. |
Methylnaltrexone Injection | Methylnaltrexone Injection Metoprolol may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level. |
Rufinamide | Rufinamide The metabolism of Metoprolol can be increased when combined with Rufinamide. |
Silodosin | Silodosin Metoprolol may increase the orthostatic hypotensive activities of Silodosin. |
Midazolam | Midazolam The metabolism of Midazolam can be decreased when combined with Metoprolol. |
Dexrazoxane Injection | Dexrazoxane Injection Metoprolol may decrease the excretion rate of Dexrazoxane which could result in a higher serum level. |
Milnacipran | Milnacipran The serum concentration of Metoprolol can be increased when it is combined with Milnacipran. |
Plerixafor Injection | Plerixafor Injection Metoprolol may decrease the excretion rate of Plerixafor which could result in a higher serum level. |
Sodium Phosphate | Sodium Phosphate Sodium phosphate, monobasic may increase the hyperkalemic activities of Metoprolol. |
Fesoterodine | Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Metoprolol. |
Betaxolol | Betaxolol The metabolism of Betaxolol can be decreased when combined with Metoprolol. |
Iloperidone | Iloperidone The metabolism of Iloperidone can be decreased when combined with Metoprolol. |
Prasugrel | Prasugrel Metoprolol may decrease the excretion rate of Prasugrel which could result in a higher serum level. |
Lacosamide | Lacosamide The metabolism of Lacosamide can be decreased when combined with Metoprolol. |
Everolimus | Everolimus The metabolism of Everolimus can be decreased when combined with Metoprolol. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be decreased when combined with Metoprolol. |
Dronedarone | Dronedarone Dronedarone may increase the bradycardic activities of Metoprolol. |
Pralatrexate Injection | Pralatrexate Injection Metoprolol may decrease the excretion rate of Pralatrexate which could result in a higher serum level. |
Palonosetron Injection | Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Metoprolol. |
Saxagliptin | Saxagliptin The therapeutic efficacy of Saxagliptin can be increased when used in combination with Metoprolol. |
Telavancin Injection | Telavancin Injection Metoprolol may decrease the excretion rate of Telavancin which could result in a higher serum level. |
Romidepsin Injection | Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Metoprolol. |
Tapentadol | Tapentadol The metabolism of Tapentadol can be decreased when combined with Metoprolol. |
Topotecan | Topotecan The metabolism of Metoprolol can be decreased when combined with Topotecan. |
Golimumab Injection | Golimumab Injection The metabolism of Metoprolol can be increased when combined with Golimumab. |
Pazopanib | Pazopanib The metabolism of Pazopanib can be decreased when combined with Metoprolol. |
Asenapine | Asenapine Metoprolol may increase the orthostatic hypotensive activities of Asenapine. |
Albendazole | Albendazole The metabolism of Albendazole can be decreased when combined with Metoprolol. |
Oxymorphone | Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Metoprolol. |
Liraglutide Injection | Liraglutide Injection The therapeutic efficacy of Liraglutide can be increased when used in combination with Metoprolol. |
Tocilizumab Injection | Tocilizumab Injection The metabolism of Metoprolol can be increased when combined with Tocilizumab. |
Dalfampridine | Dalfampridine The serum concentration of Dalfampridine can be increased when it is combined with Metoprolol. |
Fingolimod | Fingolimod Metoprolol may increase the bradycardic activities of Fingolimod. |
Cabazitaxel Injection | Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Metoprolol. |
Ceftaroline Injection | Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Lurasidone | Lurasidone Lurasidone may decrease the antihypertensive activities of Metoprolol. |
Acetaminophen Injection | Acetaminophen Injection The metabolism of Metoprolol can be decreased when combined with Acetaminophen. |
Vilazodone | Vilazodone The metabolism of Vilazodone can be decreased when combined with Metoprolol. |
Ipilimumab Injection | Ipilimumab Injection Metoprolol may decrease the excretion rate of Ipilimumab which could result in a higher serum level. |
Denileukin Diftitox Injection | Denileukin Diftitox Injection The metabolism of Metoprolol can be decreased when combined with Aldesleukin. |
Terbutaline Injection | Terbutaline Injection The therapeutic efficacy of Terbutaline can be decreased when used in combination with Metoprolol. |
Azilsartan | Azilsartan The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Azilsartan medoxomil. |
Busulfan Injection | Busulfan Injection The metabolism of Busulfan can be decreased when combined with Metoprolol. |
Roflumilast | Roflumilast The metabolism of Roflumilast can be decreased when combined with Metoprolol. |
Linagliptin | Linagliptin The therapeutic efficacy of Linagliptin can be increased when used in combination with Metoprolol. |
Rilpivirine | Rilpivirine The metabolism of Metoprolol can be decreased when combined with Rilpivirine. |
Telaprevir | Telaprevir The metabolism of Metoprolol can be decreased when combined with Glecaprevir. |
Potassium Iodide | Potassium Iodide Potassium Iodide may increase the hyperkalemic activities of Metoprolol. |
Cyclophosphamide Injection | Cyclophosphamide Injection The metabolism of Metoprolol can be decreased when combined with Cyclophosphamide. |
Abiraterone | Abiraterone The metabolism of Metoprolol can be decreased when combined with Abiraterone. |
Rivaroxaban | Rivaroxaban Metoprolol may decrease the excretion rate of Rivaroxaban which could result in a higher serum level. |
Ticagrelor | Ticagrelor The metabolism of Metoprolol can be decreased when combined with Ticagrelor. |
Brentuximab Vedotin Injection | Brentuximab Vedotin Injection The metabolism of Metoprolol can be decreased when combined with Brentuximab vedotin. |
Ruxolitinib | Ruxolitinib Ruxolitinib may increase the bradycardic activities of Metoprolol. |
Vandetanib | Vandetanib The metabolism of Vandetanib can be decreased when combined with Metoprolol. |
Clobazam | Clobazam The metabolism of Clobazam can be decreased when combined with Metoprolol. |
Vemurafenib | Vemurafenib The metabolism of Metoprolol can be decreased when combined with Vemurafenib. |
Ivacaftor | Ivacaftor The metabolism of Metoprolol can be decreased when combined with Ivacaftor. |
Deferiprone | Deferiprone Metoprolol may decrease the excretion rate of Deferiprone which could result in a higher serum level. |
Axitinib | Axitinib The metabolism of Axitinib can be decreased when combined with Metoprolol. |
Crizotinib | Crizotinib The metabolism of Metoprolol can be decreased when combined with Crizotinib. |
Cabergoline | Cabergoline The metabolism of Cabergoline can be decreased when combined with Metoprolol. |
Naloxone Injection | Naloxone Injection The metabolism of Metoprolol can be decreased when combined with Naloxone. |
Ambrisentan | Ambrisentan Metoprolol may increase the hypotensive activities of Ambrisentan. |
Fondaparinux Injection | Fondaparinux Injection Metoprolol may decrease the excretion rate of Fondaparinux which could result in a higher serum level. |
Iloprost | Iloprost Iloprost may increase the hypotensive activities of Metoprolol. |
Enzalutamide | Enzalutamide The metabolism of Metoprolol can be increased when combined with Enzalutamide. |
Mirabegron | Mirabegron Mirabegron may decrease the antihypertensive activities of Metoprolol. |
Regorafenib | Regorafenib Regorafenib may increase the bradycardic activities of Metoprolol. |
Bosutinib | Bosutinib The metabolism of Metoprolol can be decreased when combined with Bosutinib. |
Corticotropin, Repository Injection | Corticotropin, Repository Injection The metabolism of Metoprolol can be increased when combined with Corticotropin. |
Lorcaserin | Lorcaserin The therapeutic efficacy of Mecasermin can be increased when used in combination with Metoprolol. |
Teduglutide Injection | Teduglutide Injection Metoprolol may decrease the excretion rate of Teduglutide which could result in a higher serum level. |
Tofacitinib | Tofacitinib Metoprolol may increase the bradycardic activities of Tofacitinib. |
Alogliptin | Alogliptin The metabolism of Alogliptin can be decreased when combined with Metoprolol. |
Ponatinib | Ponatinib The metabolism of Metoprolol can be decreased when combined with Ponatinib. |
Pomalidomide | Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Metoprolol. |
Ado-trastuzumab Emtansine Injection | Ado-trastuzumab Emtansine Injection The metabolism of Metoprolol can be decreased when combined with Trastuzumab emtansine. |
Canagliflozin | Canagliflozin The therapeutic efficacy of Metoprolol can be increased when used in combination with Canagliflozin. |
Methazolamide | Methazolamide Methazolamide may increase the excretion rate of Metoprolol which could result in a lower serum level and potentially a reduction in efficacy. |
Dabrafenib | Dabrafenib The metabolism of Metoprolol can be decreased when combined with Dabrafenib. |
Ospemifene | Ospemifene The metabolism of Metoprolol can be decreased when combined with Ospemifene. |
Trametinib | Trametinib The metabolism of Trametinib can be increased when combined with Metoprolol. |
Levomilnacipran | Levomilnacipran The metabolism of Metoprolol can be decreased when combined with Levomilnacipran. |
Ertapenem Injection | Ertapenem Injection Metoprolol may decrease the excretion rate of Ertapenem which could result in a higher serum level. |
Vortioxetine | Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Metoprolol. |
Perampanel | Perampanel The metabolism of Metoprolol can be increased when combined with Perampanel. |
Ibrutinib | Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Metoprolol. |
Lomitapide | Lomitapide The metabolism of Metoprolol can be decreased when combined with Lomitapide. |
Avanafil | Avanafil Avanafil may increase the antihypertensive activities of Metoprolol. |
Ketorolac Injection | Ketorolac Injection Ketorolac may decrease the antihypertensive activities of Metoprolol. |
Obinutuzumab Injection | Obinutuzumab Injection Metoprolol may increase the hypotensive activities of Obinutuzumab. |
Simeprevir | Simeprevir The metabolism of Metoprolol can be decreased when combined with Simeprevir. |
Sofosbuvir | Sofosbuvir Metoprolol may decrease the excretion rate of Sofosbuvir which could result in a higher serum level. |
Dapagliflozin | Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Metoprolol. |
Apremilast | Apremilast The metabolism of Metoprolol can be increased when combined with Apremilast. |
Droxidopa | Droxidopa The therapeutic efficacy of Droxidopa can be decreased when used in combination with Metoprolol. |
Ceritinib | Ceritinib Metoprolol may increase the bradycardic activities of Ceritinib. |
Siltuximab Injection | Siltuximab Injection The metabolism of Metoprolol can be increased when combined with Siltuximab. |
Albiglutide Injection | Albiglutide Injection The therapeutic efficacy of Albiglutide can be increased when used in combination with Metoprolol. |
Eslicarbazepine | Eslicarbazepine The metabolism of Metoprolol can be increased when combined with Eslicarbazepine. |
Idelalisib | Idelalisib The metabolism of Idelalisib can be decreased when combined with Metoprolol. |
Testosterone Injection | Testosterone Injection The metabolism of Metoprolol can be increased when combined with Testosterone. |
Oritavancin Injection | Oritavancin Injection The metabolism of Metoprolol can be increased when combined with Oritavancin. |
Empagliflozin | Empagliflozin The therapeutic efficacy of Empagliflozin can be increased when used in combination with Metoprolol. |
Vorapaxar | Vorapaxar The metabolism of Vorapaxar can be decreased when combined with Metoprolol. |
Hydrocodone | Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Metoprolol. |
Suvorexant | Suvorexant The metabolism of Suvorexant can be decreased when combined with Metoprolol. |
Dulaglutide Injection | Dulaglutide Injection The therapeutic efficacy of Dulaglutide can be increased when used in combination with Metoprolol. |
Edoxaban | Edoxaban Metoprolol may decrease the excretion rate of Edoxaban which could result in a higher serum level. |
Olaparib | Olaparib The metabolism of Metoprolol can be decreased when combined with Olaparib. |
Methamphetamine | Methamphetamine The metabolism of Metoprolol can be decreased when combined with Metamfetamine. |
Tasimelteon | Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Metoprolol. |
Riociguat | Riociguat Metoprolol may increase the hypotensive activities of Riociguat. |
Lanreotide Injection | Lanreotide Injection Metoprolol may increase the bradycardic activities of Lanreotide. |
Nintedanib | Nintedanib The metabolism of Nintedanib can be decreased when combined with Metoprolol. |
Secukinumab Injection | Secukinumab Injection The metabolism of Metoprolol can be increased when combined with Secukinumab. |
Risperidone Injection | Risperidone Injection Metoprolol may increase the hypotensive activities of Risperidone. |
Palbociclib | Palbociclib The metabolism of Metoprolol can be decreased when combined with Palbociclib. |
Insulin Human Inhalation | Insulin Human Inhalation The therapeutic efficacy of Insulin human can be increased when used in combination with Metoprolol. |
Lenvatinib | Lenvatinib The metabolism of Metoprolol can be decreased when combined with Lenvatinib. |
Naloxegol | Naloxegol The metabolism of Metoprolol can be decreased when combined with Naloxegol. |
Panobinostat | Panobinostat The metabolism of Metoprolol can be decreased when combined with Panobinostat. |
Dinutuximab Injection | Dinutuximab Injection The risk or severity of adverse effects can be increased when Dinutuximab is combined with Metoprolol. |
Haloperidol Injection | Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Metoprolol. |
Ivabradine | Ivabradine Metoprolol may increase the bradycardic activities of Ivabradine. |
Amiloride | Amiloride Metoprolol may increase the excretion rate of Amiloride which could result in a lower serum level and potentially a reduction in efficacy. |
Isavuconazonium Injection | Isavuconazonium Injection The metabolism of Metoprolol can be increased when combined with Isavuconazonium. |
Macitentan | Macitentan Metoprolol may decrease the excretion rate of Macitentan which could result in a higher serum level. |
Sonidegib | Sonidegib The metabolism of Sonidegib can be decreased when combined with Metoprolol. |
Flibanserin | Flibanserin Flibanserin may decrease the antihypertensive activities of Metoprolol. |
Rolapitant | Rolapitant The metabolism of Metoprolol can be decreased when combined with Rolapitant. |
Prednisolone | Prednisolone The metabolism of Metoprolol can be increased when combined with Prednisolone. |
Brexpiprazole | Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Metoprolol. |
Ziprasidone Injection | Ziprasidone Injection Metoprolol may increase the antihypertensive activities of Ziprasidone. |
Cariprazine | Cariprazine The metabolism of Cariprazine can be decreased when combined with Metoprolol. |
Penicillin G Procaine Injection | Penicillin G Procaine Injection Metoprolol may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level. |
Insulin Degludec (rDNA Origin) Injection | Insulin Degludec (rDNA Origin) Injection The therapeutic efficacy of Insulin degludec can be increased when used in combination with Metoprolol. |
Cobimetinib | Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Metoprolol. |
Trabectedin Injection | Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Metoprolol. |
Osimertinib | Osimertinib The metabolism of Metoprolol can be decreased when combined with Osimertinib. |
Alectinib | Alectinib The metabolism of Alectinib can be decreased when combined with Metoprolol. |
Ixazomib | Ixazomib The metabolism of Ixazomib can be decreased when combined with Metoprolol. |
Rifapentine | Rifapentine The metabolism of Metoprolol can be increased when combined with Rifapentine. |
Lesinurad | Lesinurad The metabolism of Lesinurad can be increased when combined with Metoprolol. |
Amphotericin B Liposomal Injection | Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Dexamethasone Injection | Dexamethasone Injection The metabolism of Metoprolol can be increased when combined with Dexamethasone. |
Brivaracetam Injection | Brivaracetam Injection Metoprolol may decrease the excretion rate of Brivaracetam which could result in a higher serum level. |
Venetoclax | Venetoclax The metabolism of Metoprolol can be decreased when combined with Venetoclax. |
Cobicistat | Cobicistat The metabolism of Metoprolol can be decreased when combined with Cobicistat. |
Midodrine | Midodrine The therapeutic efficacy of Midodrine can be decreased when used in combination with Metoprolol. |
Selexipag | Selexipag Metoprolol may increase the hypotensive activities of Selexipag. |
Diphenhydramine Injection | Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Metoprolol. |
Furosemide Injection | Furosemide Injection Metoprolol may increase the excretion rate of Furosemide which could result in a lower serum level and potentially a reduction in efficacy. |
Rucaparib | Rucaparib The metabolism of Metoprolol can be decreased when combined with Rucaparib. |
Lixisenatide Injection | Lixisenatide Injection The therapeutic efficacy of Lixisenatide can be increased when used in combination with Metoprolol. |
Ribociclib | Ribociclib The metabolism of Metoprolol can be decreased when combined with Ribociclib. |
Brigatinib | Brigatinib The metabolism of Metoprolol can be decreased when combined with Brigatinib. |
Doxepin (Insomnia) | Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Metoprolol. |
Deutetrabenazine | Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Metoprolol. |
Valbenazine | Valbenazine The metabolism of Valbenazine can be decreased when combined with Metoprolol. |
Deflazacort | Deflazacort The metabolism of Metoprolol can be increased when combined with Deflazacort. |
Safinamide | Safinamide Safinamide may increase the hypotensive activities of Metoprolol. |
Naldemedine | Naldemedine Metoprolol may decrease the excretion rate of Naldemedine which could result in a higher serum level. |
Sarilumab Injection | Sarilumab Injection The metabolism of Metoprolol can be increased when combined with Sarilumab. |
Midostaurin | Midostaurin The metabolism of Metoprolol can be increased when combined with Midostaurin. |
Neratinib | Neratinib The metabolism of Neratinib can be decreased when combined with Metoprolol. |
Enasidenib | Enasidenib The metabolism of Metoprolol can be decreased when combined with Enasidenib. |
Aprepitant/Fosaprepitant Injection | Aprepitant/Fosaprepitant Injection The metabolism of Metoprolol can be increased when combined with Fosaprepitant. |
Benznidazole | Benznidazole Metoprolol may decrease the excretion rate of Benznidazole which could result in a higher serum level. |
Copanlisib Injection | Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Metoprolol. |
Delafloxacin | Delafloxacin Metoprolol may decrease the excretion rate of Delafloxacin which could result in a higher serum level. |
Abemaciclib | Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Metoprolol. |
Acalabrutinib | Acalabrutinib The metabolism of Metoprolol can be decreased when combined with Acalabrutinib. |
Letermovir | Letermovir The metabolism of Metoprolol can be decreased when combined with Letermovir. |
Semaglutide Injection | Semaglutide Injection The therapeutic efficacy of Semaglutide can be increased when used in combination with Metoprolol. |
Tetrabenazine | Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Metoprolol. |
Ertugliflozin | Ertugliflozin The therapeutic efficacy of Ertugliflozin can be increased when used in combination with Metoprolol. |
Buprenorphine Injection | Buprenorphine Injection The metabolism of Metoprolol can be decreased when combined with Buprenorphine. |
Apalutamide | Apalutamide The metabolism of Apalutamide can be increased when combined with Metoprolol. |
Fostamatinib | Fostamatinib The metabolism of Metoprolol can be decreased when combined with Fostamatinib. |
Baricitinib | Baricitinib The metabolism of Baricitinib can be decreased when combined with Metoprolol. |
Lofexidine | Lofexidine The metabolism of Lofexidine can be decreased when combined with Metoprolol. |
Plazomicin Injection | Plazomicin Injection Metoprolol may decrease the excretion rate of Plazomicin which could result in a higher serum level. |
Eliglustat | Eliglustat The metabolism of Eliglustat can be decreased when combined with Metoprolol. |
Encorafenib | Encorafenib The metabolism of Encorafenib can be decreased when combined with Metoprolol. |
Ivosidenib | Ivosidenib The metabolism of Metoprolol can be decreased when combined with Ivosidenib. |
Elagolix | Elagolix The metabolism of Elagolix can be decreased when combined with Metoprolol. |
Tafenoquine | Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Metoprolol. |
Cannabidiol | Cannabidiol The metabolism of Metoprolol can be decreased when combined with Cannabidiol. |
Dacomitinib | Dacomitinib The metabolism of Metoprolol can be decreased when combined with Dacomitinib. |
Duvelisib | Duvelisib The metabolism of Duvelisib can be decreased when combined with Metoprolol. |
Stiripentol | Stiripentol The metabolism of Metoprolol can be decreased when combined with Stiripentol. |
Gilteritinib | Gilteritinib The metabolism of Gilteritinib can be decreased when combined with Metoprolol. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Metoprolol. |
Rifamycin | Rifamycin The metabolism of Metoprolol can be increased when combined with Rifamycin. |
Prucalopride | Prucalopride The metabolism of Prucalopride can be decreased when combined with Metoprolol. |
Emapalumab-lzsg Injection | Emapalumab-lzsg Injection The metabolism of Metoprolol can be increased when combined with Emapalumab. |
Siponimod | Siponimod The metabolism of Siponimod can be decreased when combined with Metoprolol. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Erdafitinib | Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Metoprolol. |
Alpelisib | Alpelisib The metabolism of Metoprolol can be decreased when combined with Alpelisib. |
Solriamfetol | Solriamfetol The serum concentration of Solriamfetol can be increased when it is combined with Metoprolol. |
Triclabendazole | Triclabendazole The metabolism of Triclabendazole can be decreased when combined with Metoprolol. |
Entrectinib | Entrectinib The metabolism of Entrectinib can be decreased when combined with Metoprolol. |
Pexidartinib | Pexidartinib The metabolism of Pexidartinib can be decreased when combined with Metoprolol. |
Istradefylline | Istradefylline The metabolism of Istradefylline can be decreased when combined with Metoprolol. |
Pitolisant | Pitolisant The serum concentration of Metoprolol can be decreased when it is combined with Pitolisant. |
Fedratinib | Fedratinib The metabolism of Metoprolol can be decreased when combined with Fedratinib. |
Lefamulin | Lefamulin The metabolism of Lefamulin can be decreased when combined with Metoprolol. |
Phenytoin Injection | Phenytoin Injection The metabolism of Metoprolol can be increased when combined with Phenytoin. |
Fosphenytoin Injection | Fosphenytoin Injection The metabolism of Metoprolol can be increased when combined with Fosphenytoin. |
Zanubrutinib | Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Metoprolol. |
Lasmiditan | Lasmiditan Lasmiditan may increase the bradycardic activities of Metoprolol. |
Calcium Acetate | Calcium Acetate The therapeutic efficacy of Metoprolol can be decreased when used in combination with Calcium acetate. |
Tazemetostat | Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Metoprolol. |
Cenobamate | Cenobamate The serum concentration of Metoprolol can be decreased when it is combined with Cenobamate. |
Tucatinib | Tucatinib The metabolism of Tucatinib can be decreased when combined with Metoprolol. |
Selpercatinib | Selpercatinib Selpercatinib may decrease the antihypertensive activities of Metoprolol. |
Fenfluramine | Fenfluramine The metabolism of Metoprolol can be decreased when combined with Fenfluramine. |
Octreotide | Octreotide The serum concentration of the active metabolites of Metoprolol can be increased when Metoprolol is used in combination with Octreotide. |
Pralsetinib | Pralsetinib The metabolism of Metoprolol can be increased when combined with Pralsetinib. |
Satralizumab-mwge Injection | Satralizumab-mwge Injection The serum concentration of Metoprolol can be decreased when it is combined with Satralizumab. |
Naxitamab-gqgk Injection | Naxitamab-gqgk Injection Naxitamab may decrease the antihypertensive activities of Metoprolol. |
Progestin-Only (drospirenone) Oral Contraceptives | Progestin-Only (drospirenone) Oral Contraceptives Metoprolol may increase the excretion rate of Drospirenone which could result in a lower serum level and potentially a reduction in efficacy. |
Viloxazine | Viloxazine Metoprolol may decrease the excretion rate of Viloxazine which could result in a higher serum level. |
Vitamin E (Alpha-Tocopherol) | Vitamin E (Alpha-Tocopherol) The metabolism of Metoprolol can be increased when combined with Vitamin E. |
Tobramycin Injection | Tobramycin Injection Tobramycin may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Theophylline | Theophylline The metabolism of Theophylline can be decreased when combined with Metoprolol. |
Fenoprofen | Fenoprofen Fenoprofen may decrease the antihypertensive activities of Metoprolol. |
Indomethacin | Indomethacin Indomethacin may decrease the antihypertensive activities of Metoprolol. |
Mefenamic Acid | Mefenamic Acid Mefenamic acid may decrease the antihypertensive activities of Metoprolol. |
Naproxen | Naproxen Naproxen may decrease the antihypertensive activities of Metoprolol. |
Tolmetin | Tolmetin Tolmetin may decrease the antihypertensive activities of Metoprolol. |
Sulindac | Sulindac Sulindac may decrease the antihypertensive activities of Metoprolol. |
Trazodone | Trazodone The metabolism of Metoprolol can be decreased when combined with Trazodone. |
Isotretinoin | Isotretinoin Metoprolol may decrease the excretion rate of Isotretinoin which could result in a higher serum level. |
Sucralfate | Sucralfate Metoprolol may decrease the excretion rate of Sucralfate which could result in a higher serum level. |
Hydroxyurea | Hydroxyurea The metabolism of Metoprolol can be decreased when combined with Hydroxyurea. |
Floxuridine | Floxuridine Metoprolol may decrease the excretion rate of Floxuridine which could result in a higher serum level. |
Phenobarbital | Phenobarbital The metabolism of Metoprolol can be increased when combined with Phenobarbital. |
Metaxalone | Metaxalone Metoprolol may decrease the excretion rate of Metaxalone which could result in a higher serum level. |
Methotrexate Injection | Methotrexate Injection The metabolism of Metoprolol can be decreased when combined with Methotrexate. |
Primidone | Primidone The metabolism of Metoprolol can be increased when combined with Primidone. |
Methsuximide | Methsuximide The risk or severity of bradycardia can be increased when Methsuximide is combined with Metoprolol. |
Diethylpropion | Diethylpropion The therapeutic efficacy of Metoprolol can be decreased when used in combination with Diethylpropion. |
Chlorpromazine | Chlorpromazine The metabolism of Metoprolol can be decreased when combined with Chlorpromazine. |
Diazepam | Diazepam The metabolism of Metoprolol can be decreased when combined with Diazepam. |
Oxazepam | Oxazepam Metoprolol may decrease the excretion rate of Oxazepam which could result in a higher serum level. |
Flurazepam | Flurazepam Metoprolol may decrease the excretion rate of Flurazepam which could result in a higher serum level. |
Clorazepate | Clorazepate Metoprolol may decrease the excretion rate of Clorazepic acid which could result in a higher serum level. |
Phenoxybenzamine | Phenoxybenzamine Metoprolol may increase the orthostatic hypotensive activities of Phenoxybenzamine. |
Carmustine | Carmustine Carmustine may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Amantadine | Amantadine The serum concentration of Amantadine can be increased when it is combined with Metoprolol. |
Codeine | Codeine The metabolism of Codeine can be decreased when combined with Metoprolol. |
Bromocriptine | Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Metoprolol. |
Metaproterenol | Metaproterenol The therapeutic efficacy of Orciprenaline can be decreased when used in combination with Metoprolol. |
Tranylcypromine | Tranylcypromine The metabolism of Metoprolol can be decreased when combined with Tranylcypromine. |
Phenelzine | Phenelzine Phenelzine may increase the hypotensive activities of Metoprolol. |
Procarbazine | Procarbazine Procarbazine may increase the hypotensive activities of Metoprolol. |
Ergoloid Mesylates | Ergoloid Mesylates Metoprolol may increase the vasoconstricting activities of Ergoloid mesylate. |
Tetracycline | Tetracycline The metabolism of Metoprolol can be decreased when combined with Tetracycline. |
Prochlorperazine | Prochlorperazine The metabolism of Metoprolol can be decreased when combined with Prochlorperazine. |
Thioridazine | Thioridazine The metabolism of Metoprolol can be decreased when combined with Thioridazine. |
Trifluoperazine | Trifluoperazine The serum concentration of Metoprolol can be increased when it is combined with Trifluoperazine. |
Bleomycin | Bleomycin Metoprolol may decrease the excretion rate of Bleomycin which could result in a higher serum level. |
Sulfadiazine | Sulfadiazine The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Metoprolol. |
Oxycodone | Oxycodone The metabolism of Oxycodone can be decreased when combined with Metoprolol. |
Methadone | Methadone The metabolism of Methadone can be decreased when combined with Metoprolol. |
Oxybutynin | Oxybutynin The metabolism of Metoprolol can be decreased when combined with Oxybutynin. |
Benztropine | Benztropine The metabolism of Metoprolol can be decreased when combined with Benzatropine. |
Maprotiline | Maprotiline The metabolism of Maprotiline can be decreased when combined with Metoprolol. |
Ibuprofen | Ibuprofen Ibuprofen may decrease the antihypertensive activities of Metoprolol. |
Orphenadrine | Orphenadrine The metabolism of Metoprolol can be decreased when combined with Orphenadrine. |
Perphenazine | Perphenazine The metabolism of Metoprolol can be decreased when combined with Perphenazine. |
Azathioprine | Azathioprine Metoprolol may decrease the excretion rate of Azathioprine which could result in a higher serum level. |
Fluphenazine | Fluphenazine The serum concentration of Metoprolol can be increased when it is combined with Fluphenazine. |
Phentermine | Phentermine The therapeutic efficacy of Metoprolol can be decreased when used in combination with Phentermine. |
Methylphenidate | Methylphenidate Methylphenidate may decrease the antihypertensive activities of Metoprolol. |
Amoxapine | Amoxapine The metabolism of Amoxapine can be decreased when combined with Metoprolol. |
Sulfasalazine | Sulfasalazine Sulfasalazine may decrease the antihypertensive activities of Metoprolol. |
Hydrocortisone | Hydrocortisone The metabolism of Metoprolol can be increased when combined with Hydrocortisone. |
Doxorubicin | Doxorubicin The metabolism of Metoprolol can be decreased when combined with Doxorubicin. |
Mechlorethamine | Mechlorethamine Mechlorethamine may increase the bradycardic activities of Metoprolol. |
Pyridostigmine | Pyridostigmine Pyridostigmine may increase the bradycardic activities of Metoprolol. |
Phenazopyridine | Phenazopyridine Phenazopyridine may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Carbamazepine | Carbamazepine The metabolism of Carbamazepine can be increased when combined with Metoprolol. |
Methyldopa | Methyldopa The therapeutic efficacy of Methyldopa can be decreased when used in combination with Metoprolol. |
Clonidine | Clonidine The risk or severity of hypotension can be increased when Clonidine is combined with Metoprolol. |
Prazosin | Prazosin The risk or severity of hypotension can be increased when Prazosin is combined with Metoprolol. |
Hydralazine | Hydralazine The metabolism of Hydralazine can be decreased when combined with Metoprolol. |
Cimetidine | Cimetidine The metabolism of Cimetidine can be decreased when combined with Metoprolol. |
Gentamicin Injection | Gentamicin Injection Gentamicin may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Warfarin | Warfarin The metabolism of Warfarin can be decreased when combined with Metoprolol. |
Clonazepam | Clonazepam Metoprolol may decrease the excretion rate of Clonazepam which could result in a higher serum level. |
Loperamide | Loperamide The metabolism of Metoprolol can be decreased when combined with Loperamide. |
Promethazine | Promethazine The metabolism of Metoprolol can be decreased when combined with Promethazine. |
Meclofenamate | Meclofenamate Meclofenamic acid may decrease the antihypertensive activities of Metoprolol. |
Daunorubicin | Daunorubicin The metabolism of Metoprolol can be decreased when combined with Daunorubicin. |
Nitrofurantoin | Nitrofurantoin The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Nitrofurantoin. |
Griseofulvin | Griseofulvin The metabolism of Metoprolol can be increased when combined with Griseofulvin. |
Digoxin | Digoxin Metoprolol may increase the arrhythmogenic activities of Digoxin. |
Chloroquine | Chloroquine The metabolism of Metoprolol can be decreased when combined with Chloroquine. |
Quinine | Quinine The metabolism of Metoprolol can be decreased when combined with Quinine. |
Ethosuximide | Ethosuximide The risk or severity of bradycardia can be increased when Metoprolol is combined with Ethosuximide. |
Calcitriol | Calcitriol The metabolism of Metoprolol can be increased when combined with Calcitriol. |
Triamterene | Triamterene Metoprolol may decrease the excretion rate of Triamterene which could result in a higher serum level. |
Sulfinpyrazone | Sulfinpyrazone The metabolism of Metoprolol can be increased when combined with Sulfinpyrazone. |
Chlorothiazide | Chlorothiazide The therapeutic efficacy of Chlorothiazide can be increased when used in combination with Metoprolol. |
Chlorthalidone | Chlorthalidone Metoprolol may increase the excretion rate of Chlorthalidone which could result in a lower serum level and potentially a reduction in efficacy. |
Metolazone | Metolazone Metoprolol may increase the excretion rate of Metolazone which could result in a lower serum level and potentially a reduction in efficacy. |
Isosorbide | Isosorbide Isosorbide may increase the excretion rate of Metoprolol which could result in a lower serum level and potentially a reduction in efficacy. |
Secobarbital | Secobarbital The serum concentration of Metoprolol can be decreased when it is combined with Secobarbital. |
Desipramine | Desipramine The metabolism of Desipramine can be decreased when combined with Metoprolol. |
Amitriptyline | Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Metoprolol. |
Imipramine | Imipramine The metabolism of Imipramine can be decreased when combined with Metoprolol. |
Probenecid | Probenecid The metabolism of Probenecid can be increased when combined with Metoprolol. |
Quinidine | Quinidine Quinidine may increase the arrhythmogenic activities of Metoprolol. |
Procainamide | Procainamide The metabolism of Procainamide can be decreased when combined with Metoprolol. |
Isoniazid | Isoniazid The metabolism of Isoniazid can be decreased when combined with Metoprolol. |
Pyrazinamide | Pyrazinamide Metoprolol may decrease the excretion rate of Pyrazinamide which could result in a higher serum level. |
Rifampin | Rifampin The metabolism of Metoprolol can be increased when combined with Rifampicin. |
Disopyramide | Disopyramide Disopyramide may increase the bradycardic activities of Metoprolol. |
Valproic Acid | Valproic Acid The metabolism of Metoprolol can be decreased when combined with Valproic acid. |
Tamoxifen | Tamoxifen The metabolism of Metoprolol can be decreased when combined with Tamoxifen. |
Butabarbital | Butabarbital Butabarbital may increase the hypotensive activities of Metoprolol. |
Levothyroxine | Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Metoprolol. |
Liothyronine | Liothyronine The therapeutic efficacy of Liothyronine can be decreased when used in combination with Metoprolol. |
Methimazole | Methimazole The excretion of Methimazole can be decreased when combined with Metoprolol. |
Chlorpropamide | Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Metoprolol. |
Glucagon Injection | Glucagon Injection The therapeutic efficacy of Metoprolol can be decreased when used in combination with Glucagon. |
Tolbutamide | Tolbutamide The therapeutic efficacy of Tolbutamide can be increased when used in combination with Metoprolol. |
Tolazamide | Tolazamide The therapeutic efficacy of Tolazamide can be increased when used in combination with Metoprolol. |
Dextromethorphan | Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Metoprolol. |
Niacin | Niacin The metabolism of Metoprolol can be decreased when combined with Niacin. |
Baclofen | Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Metoprolol. |
Clemastine | Clemastine The metabolism of Metoprolol can be decreased when combined with Clemastine. |
Chlorpheniramine | Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Metoprolol. |
Meclizine | Meclizine The metabolism of Meclizine can be decreased when combined with Metoprolol. |
Ethambutol | Ethambutol Metoprolol may decrease the excretion rate of Ethambutol which could result in a higher serum level. |
Methyclothiazide | Methyclothiazide The therapeutic efficacy of Metoprolol can be increased when used in combination with Methyclothiazide. |
Dantrolene | Dantrolene The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Dantrolene. |
Chlorzoxazone | Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Metoprolol. |
Pyridoxine | Pyridoxine Pyridoxine may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Folic Acid | Folic Acid Folic acid may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Danazol | Danazol The metabolism of Metoprolol can be decreased when combined with Danazol. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The metabolism of Propranolol can be decreased when combined with Metoprolol. |
Minoxidil | Minoxidil Metoprolol may increase the hypotensive activities of Minoxidil. |
Pseudoephedrine | Pseudoephedrine The therapeutic efficacy of Metoprolol can be decreased when used in combination with Pseudoephedrine. |
Nortriptyline | Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Metoprolol. |
Spironolactone | Spironolactone Metoprolol may increase the excretion rate of Spironolactone which could result in a lower serum level and potentially a reduction in efficacy. |
Amphotericin B Injection | Amphotericin B Injection Amphotericin B may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Mercaptopurine | Mercaptopurine The therapeutic efficacy of Mercaptopurine can be decreased when used in combination with Metoprolol. |
Phytonadione | Phytonadione Metoprolol may decrease the excretion rate of Phylloquinone which could result in a higher serum level. |
Amikacin Injection | Amikacin Injection Amikacin may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Nadolol | Nadolol The metabolism of Nadolol can be decreased when combined with Metoprolol. |
Allopurinol | Allopurinol Metoprolol may decrease the excretion rate of Allopurinol which could result in a higher serum level. |
Flavoxate | Flavoxate Metoprolol may decrease the excretion rate of Flavoxate which could result in a higher serum level. |
Papaverine | Papaverine The risk or severity of adverse effects can be increased when Papaverine is combined with Metoprolol. |
Colchicine | Colchicine The metabolism of Metoprolol can be increased when combined with Colchicine. |
Cefaclor | Cefaclor Cefaclor may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Cefadroxil | Cefadroxil Cefadroxil may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Cefazolin Injection | Cefazolin Injection Cefazolin may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Cephalexin | Cephalexin Cephalexin may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Cefoxitin Injection | Cefoxitin Injection Cefoxitin may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Dacarbazine | Dacarbazine Metoprolol may decrease the excretion rate of Dacarbazine which could result in a higher serum level. |
Acetazolamide | Acetazolamide The metabolism of Metoprolol can be decreased when combined with Acetazolamide. |
Cefotaxime Injection | Cefotaxime Injection Cefotaxime may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Calcitonin Salmon Injection | Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Ketoconazole | Ketoconazole The metabolism of Metoprolol can be decreased when combined with Ketoconazole. |
Pyrantel | Pyrantel Metoprolol may decrease the excretion rate of Pyrantel which could result in a higher serum level. |
Thiotepa Injection | Thiotepa Injection The metabolism of Metoprolol can be decreased when combined with Thiotepa. |
Vincristine Injection | Vincristine Injection The metabolism of Vincristine can be decreased when combined with Metoprolol. |
Captopril | Captopril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Captopril. |
Dipyridamole | Dipyridamole Dipyridamole may increase the bradycardic activities of Metoprolol. |
Isoxsuprine | Isoxsuprine The therapeutic efficacy of Isoxsuprine can be decreased when used in combination with Metoprolol. |
Vinblastine | Vinblastine The metabolism of Metoprolol can be decreased when combined with Vinblastine. |
Bethanechol | Bethanechol The risk or severity of adverse effects can be increased when Metoprolol is combined with Bethanechol. |
Ethacrynic Acid | Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Colistimethate Injection | Colistimethate Injection Colistimethate may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Hydroxyzine | Hydroxyzine The metabolism of Metoprolol can be decreased when combined with Hydroxyzine. |
Aspirin | Aspirin Acetylsalicylic acid may decrease the antihypertensive activities of Metoprolol. |
Salsalate | Salsalate Salsalate may decrease the antihypertensive activities of Metoprolol. |
Alprazolam | Alprazolam Metoprolol may decrease the excretion rate of Alprazolam which could result in a higher serum level. |
Temazepam | Temazepam Temazepam may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Triazolam | Triazolam Metoprolol may decrease the excretion rate of Triazolam which could result in a higher serum level. |
Dicyclomine | Dicyclomine Metoprolol may decrease the excretion rate of Dicyclomine which could result in a higher serum level. |
Hyoscyamine | Hyoscyamine Metoprolol may increase the arrhythmogenic activities of Hyoscyamine. |
Propantheline | Propantheline Metoprolol may decrease the excretion rate of Propantheline which could result in a higher serum level. |
Trimethoprim | Trimethoprim Metoprolol may decrease the excretion rate of Trimethoprim which could result in a higher serum level. |
Diltiazem | Diltiazem The metabolism of Metoprolol can be decreased when combined with Diltiazem. |
Nifedipine | Nifedipine The risk or severity of congestive heart failure and hypotension can be increased when Nifedipine is combined with Metoprolol. |
Timolol | Timolol The risk or severity of adverse effects can be increased when Timolol is combined with Metoprolol. |
Verapamil | Verapamil The risk or severity of adverse effects can be increased when Metoprolol is combined with Verapamil. |
Atenolol | Atenolol The metabolism of Atenolol can be decreased when combined with Metoprolol. |
Pindolol | Pindolol The metabolism of Pindolol can be decreased when combined with Metoprolol. |
Cisplatin Injection | Cisplatin Injection The serum concentration of Cisplatin can be increased when it is combined with Metoprolol. |
Diflunisal | Diflunisal Diflunisal may decrease the antihypertensive activities of Metoprolol. |
Piroxicam | Piroxicam Piroxicam may decrease the antihypertensive activities of Metoprolol. |
Bumetanide | Bumetanide Metoprolol may increase the excretion rate of Bumetanide which could result in a lower serum level and potentially a reduction in efficacy. |
Etoposide | Etoposide The metabolism of Metoprolol can be decreased when combined with Etoposide. |
Glyburide | Glyburide The therapeutic efficacy of Glyburide can be increased when used in combination with Metoprolol. |
Glipizide | Glipizide The therapeutic efficacy of Glipizide can be increased when used in combination with Metoprolol. |
Indapamide | Indapamide The therapeutic efficacy of Indapamide can be increased when used in combination with Metoprolol. |
Amoxicillin | Amoxicillin Metoprolol may decrease the excretion rate of Amoxicillin which could result in a higher serum level. |
Dicloxacillin | Dicloxacillin The metabolism of Metoprolol can be increased when combined with Dicloxacillin. |
Nafcillin Injection | Nafcillin Injection The metabolism of Metoprolol can be increased when combined with Nafcillin. |
Oxacillin Injection | Oxacillin Injection Metoprolol may decrease the excretion rate of Oxacillin which could result in a higher serum level. |
Pentoxifylline | Pentoxifylline Pentoxifylline may increase the hypotensive activities of Metoprolol. |
Pentamidine Injection | Pentamidine Injection The metabolism of Metoprolol can be decreased when combined with Pentamidine. |
Ceftriaxone Injection | Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Labetalol | Labetalol The metabolism of Labetalol can be decreased when combined with Metoprolol. |
Auranofin | Auranofin Metoprolol may decrease the excretion rate of Auranofin which could result in a higher serum level. |
Leuprolide Injection | Leuprolide Injection Leuprolide may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Gemfibrozil | Gemfibrozil Metoprolol may decrease the excretion rate of Gemfibrozil which could result in a higher serum level. |
Guanabenz | Guanabenz The therapeutic efficacy of Guanabenz can be decreased when used in combination with Metoprolol. |
Dipivefrin Ophthalmic | Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Ceftazidime Injection | Ceftazidime Injection Ceftazidime may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Ketoprofen | Ketoprofen Ketoprofen may decrease the antihypertensive activities of Metoprolol. |
Cefotetan Injection | Cefotetan Injection Cefotetan may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Pimozide | Pimozide The metabolism of Pimozide can be decreased when combined with Metoprolol. |
Enalapril | Enalapril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Enalapril. |
Flurbiprofen | Flurbiprofen Flurbiprofen may decrease the antihypertensive activities of Metoprolol. |
Amiodarone | Amiodarone The therapeutic efficacy of Metoprolol can be increased when used in combination with Amiodarone. |
Aztreonam Injection | Aztreonam Injection Metoprolol may decrease the excretion rate of Aztreonam which could result in a higher serum level. |
Buspirone | Buspirone The metabolism of Buspirone can be decreased when combined with Metoprolol. |
Lovastatin | Lovastatin The metabolism of Metoprolol can be decreased when combined with Lovastatin. |
Ciprofloxacin | Ciprofloxacin The metabolism of Ciprofloxacin can be decreased when combined with Metoprolol. |
Mesalamine | Mesalamine Mesalazine may decrease the antihypertensive activities of Metoprolol. |
Diclofenac | Diclofenac Diclofenac may decrease the antihypertensive activities of Metoprolol. |
Fluoxetine | Fluoxetine The serum concentration of Metoprolol can be increased when it is combined with Fluoxetine. |
Nimodipine | Nimodipine The risk or severity of bradycardia can be increased when Nimodipine is combined with Metoprolol. |
Clozapine | Clozapine The metabolism of Clozapine can be decreased when combined with Metoprolol. |
Estazolam | Estazolam Metoprolol may decrease the excretion rate of Estazolam which could result in a higher serum level. |
Idarubicin | Idarubicin The metabolism of Idarubicin can be decreased when combined with Metoprolol. |
Didanosine | Didanosine Metoprolol may decrease the excretion rate of Didanosine which could result in a higher serum level. |
Pentostatin Injection | Pentostatin Injection Metoprolol may decrease the excretion rate of Pentostatin which could result in a higher serum level. |
Clarithromycin | Clarithromycin The metabolism of Metoprolol can be decreased when combined with Clarithromycin. |
Benazepril | Benazepril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Benazepril. |
Etodolac | Etodolac Etodolac may decrease the antihypertensive activities of Metoprolol. |
Felodipine | Felodipine The risk or severity of bradycardia can be increased when Metoprolol is combined with Felodipine. |
Fosinopril | Fosinopril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Fosinopril. |
Nabumetone | Nabumetone Nabumetone may decrease the antihypertensive activities of Metoprolol. |
Quinapril | Quinapril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Quinapril. |
Ramipril | Ramipril Ramipril may increase the hypotensive activities of Metoprolol. |
Simvastatin | Simvastatin The metabolism of Simvastatin can be decreased when combined with Metoprolol. |
Amlodipine | Amlodipine The risk or severity of bradycardia can be increased when Amlodipine is combined with Metoprolol. |
Teniposide Injection | Teniposide Injection The metabolism of Metoprolol can be decreased when combined with Teniposide. |
Itraconazole | Itraconazole The metabolism of Metoprolol can be decreased when combined with Itraconazole. |
Lisinopril | Lisinopril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Lisinopril. |
Oxaprozin | Oxaprozin Oxaprozin may decrease the antihypertensive activities of Metoprolol. |
Rifabutin | Rifabutin The metabolism of Metoprolol can be increased when combined with Rifabutin. |
Sotalol | Sotalol The metabolism of Sotalol can be decreased when combined with Metoprolol. |
Bisoprolol | Bisoprolol The risk or severity of adverse effects can be increased when Bisoprolol is combined with Metoprolol. |
Zolpidem | Zolpidem The metabolism of Zolpidem can be decreased when combined with Metoprolol. |
Doxazosin | Doxazosin The metabolism of Doxazosin can be decreased when combined with Metoprolol. |
Terazosin | Terazosin Metoprolol may increase the orthostatic hypotensive activities of Terazosin. |
Isradipine | Isradipine The risk or severity of bradycardia can be increased when Isradipine is combined with Metoprolol. |
Omeprazole | Omeprazole The metabolism of Metoprolol can be increased when combined with Omeprazole. |
Cisapride | Cisapride The metabolism of Cisapride can be decreased when combined with Metoprolol. |
Fluvastatin | Fluvastatin The metabolism of Metoprolol can be decreased when combined with Fluvastatin. |
Venlafaxine | Venlafaxine The serum concentration of Venlafaxine can be increased when it is combined with Metoprolol. |
Nizatidine | Nizatidine Nizatidine may increase the bradycardic activities of Metoprolol. |
Famciclovir | Famciclovir The metabolism of Famciclovir can be decreased when combined with Metoprolol. |
Fluvoxamine | Fluvoxamine The metabolism of Metoprolol can be decreased when combined with Fluvoxamine. |
Nefazodone | Nefazodone The metabolism of Metoprolol can be decreased when combined with Nefazodone. |
Lamotrigine | Lamotrigine The risk or severity of bradycardia can be increased when Metoprolol is combined with Lamotrigine. |
Losartan | Losartan Losartan may increase the arrhythmogenic activities of Metoprolol. |
Valacyclovir | Valacyclovir Valaciclovir may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Tramadol | Tramadol The metabolism of Metoprolol can be decreased when combined with Tramadol. |
Vinorelbine Injection | Vinorelbine Injection The metabolism of Metoprolol can be decreased when combined with Vinorelbine. |
Carboplatin Injection | Carboplatin Injection Carboplatin may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Moexipril | Moexipril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Moexipril. |
Lansoprazole | Lansoprazole The metabolism of Metoprolol can be increased when combined with Lansoprazole. |
Ifosfamide Injection | Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Metoprolol. |
Nicardipine | Nicardipine The metabolism of Nicardipine can be decreased when combined with Metoprolol. |
Bupropion | Bupropion The metabolism of Metoprolol can be decreased when combined with Bupropion. |
Ticlopidine | Ticlopidine The metabolism of Metoprolol can be decreased when combined with Ticlopidine. |
Saquinavir | Saquinavir The metabolism of Saquinavir can be decreased when combined with Metoprolol. |
Metformin | Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Metoprolol. |
Dalteparin Injection | Dalteparin Injection The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Dalteparin. |
Nisoldipine | Nisoldipine The risk or severity of bradycardia can be increased when Metoprolol is combined with Nisoldipine. |
Lamivudine | Lamivudine The serum concentration of Lamivudine can be increased when it is combined with Metoprolol. |
Amifostine Injection | Amifostine Injection Metoprolol may increase the hypotensive activities of Amifostine. |
Acarbose | Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Metoprolol. |
Glimepiride | Glimepiride Metoprolol may increase the arrhythmogenic activities of Glimepiride. |
Gemcitabine Injection | Gemcitabine Injection Metoprolol may decrease the excretion rate of Gemcitabine which could result in a higher serum level. |
Ritonavir | Ritonavir The serum concentration of Metoprolol can be increased when it is combined with Ritonavir. |
Docetaxel Injection | Docetaxel Injection The metabolism of Metoprolol can be decreased when combined with Docetaxel. |
Cidofovir Injection | Cidofovir Injection Cidofovir may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Meropenem Injection | Meropenem Injection Metoprolol may decrease the excretion rate of Meropenem which could result in a higher serum level. |
Clomipramine | Clomipramine The metabolism of Clomipramine can be decreased when combined with Metoprolol. |
Zafirlukast | Zafirlukast The metabolism of Metoprolol can be decreased when combined with Zafirlukast. |
Fosfomycin | Fosfomycin Metoprolol may decrease the excretion rate of Fosfomycin which could result in a higher serum level. |
Mirtazapine | Mirtazapine The metabolism of Mirtazapine can be decreased when combined with Metoprolol. |
Trandolapril | Trandolapril The risk or severity of hyperkalemia can be increased when Metoprolol is combined with Trandolapril. |
Topiramate | Topiramate The metabolism of Metoprolol can be increased when combined with Topiramate. |
Valsartan | Valsartan The risk or severity of hyperkalemia can be increased when Valsartan is combined with Metoprolol. |
Insulin Lispro Injection | Insulin Lispro Injection The therapeutic efficacy of Insulin lispro can be increased when used in combination with Metoprolol. |
Pramipexole | Pramipexole The serum concentration of Pramipexole can be increased when it is combined with Metoprolol. |
Donepezil | Donepezil The metabolism of Donepezil can be decreased when combined with Metoprolol. |
Nelfinavir | Nelfinavir The metabolism of Metoprolol can be decreased when combined with Nelfinavir. |
Azithromycin | Azithromycin The metabolism of Metoprolol can be decreased when combined with Azithromycin. |
Carvedilol | Carvedilol The metabolism of Carvedilol can be decreased when combined with Metoprolol. |
Nilutamide | Nilutamide Metoprolol may decrease the excretion rate of Nilutamide which could result in a higher serum level. |
Flutamide | Flutamide Metoprolol may decrease the excretion rate of Flutamide which could result in a higher serum level. |
Selegiline | Selegiline The metabolism of Metoprolol can be decreased when combined with Selegiline. |
Bicalutamide | Bicalutamide The metabolism of Metoprolol can be decreased when combined with Bicalutamide. |
Sertraline | Sertraline The metabolism of Metoprolol can be decreased when combined with Sertraline. |
Propafenone | Propafenone The risk or severity of adverse effects can be increased when Propafenone is combined with Metoprolol. |
Raloxifene | Raloxifene The metabolism of Metoprolol can be decreased when combined with Raloxifene. |
Irbesartan | Irbesartan The metabolism of Irbesartan can be decreased when combined with Metoprolol. |
Tamsulosin | Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Metoprolol. |
Ropinirole | Ropinirole The risk or severity of adverse effects can be increased when Ropinirole is combined with Metoprolol. |
Finasteride | Finasteride Finasteride may decrease the antihypertensive activities of Metoprolol. |
Quetiapine | Quetiapine Metoprolol may increase the hypotensive activities of Quetiapine. |
Cefepime Injection | Cefepime Injection Cefepime may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Cefprozil | Cefprozil Cefprozil may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Cefpodoxime | Cefpodoxime Cefpodoxime may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Cetirizine | Cetirizine Metoprolol may decrease the excretion rate of Cetirizine which could result in a higher serum level. |
Paroxetine | Paroxetine The metabolism of Metoprolol can be decreased when combined with Paroxetine. |
Tolcapone | Tolcapone Metoprolol may decrease the excretion rate of Tolcapone which could result in a higher serum level. |
Citalopram | Citalopram The metabolism of Metoprolol can be decreased when combined with Citalopram. |
Capecitabine | Capecitabine Metoprolol may decrease the excretion rate of Capecitabine which could result in a higher serum level. |
Efavirenz | Efavirenz The metabolism of Metoprolol can be decreased when combined with Efavirenz. |
Abacavir | Abacavir Metoprolol may decrease the excretion rate of Abacavir which could result in a higher serum level. |
Sildenafil | Sildenafil The metabolism of Sildenafil can be decreased when combined with Metoprolol. |
Pioglitazone | Pioglitazone The therapeutic efficacy of Metoprolol can be increased when used in combination with Pioglitazone. |
Celecoxib | Celecoxib Celecoxib may decrease the antihypertensive activities of Metoprolol. |
Rosiglitazone | Rosiglitazone The therapeutic efficacy of Metoprolol can be increased when used in combination with Rosiglitazone. |
Tolterodine | Tolterodine The metabolism of Tolterodine can be decreased when combined with Metoprolol. |
Thalidomide | Thalidomide The risk or severity of adverse effects can be increased when Thalidomide is combined with Metoprolol. |
Oseltamivir | Oseltamivir Oseltamivir may decrease the excretion rate of Metoprolol which could result in a higher serum level. |
Balsalazide | Balsalazide Balsalazide may decrease the antihypertensive activities of Metoprolol. |
Nateglinide | Nateglinide The metabolism of Nateglinide can be decreased when combined with Metoprolol. |
Galantamine | Galantamine The metabolism of Galantamine can be decreased when combined with Metoprolol. |
Rabeprazole | Rabeprazole The metabolism of Rabeprazole can be decreased when combined with Metoprolol. |
Terbinafine | Terbinafine The metabolism of Metoprolol can be decreased when combined with Terbinafine. |
* This branded product is no longer on the market. Generic alternatives may be available.
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists