Oxymetazoline Nasal Spray

Generic name: Pronounced as (ok'' see met az' oh leen)
Brand names
  • Afrin® Nasal Spray
  • Anefrin® Nasal Spray
  • Dristan® Nasal Spray
  • Mucinex® Nasal Spray
  • Nostrilla® Nasal Spray
  • Vicks Sinex® Nasal Spray
  • Zicam® Nasal Spray
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 09/15/2016

Oxymetazoline nasal spray is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also used to relieve sinus congestion and pressure. Oxymetazoline nasal spray should not be used to treat children younger than 6 years of age unless it is recommended by a doctor. Children 6 to 12 years of age should use oxymetazoline nasal spray carefully and under adult supervision. Oxymetazoline is in a class of medications called nasal decongestants. It works by narrowing the blood vessels in the nasal passages.

Oxymetazoline comes as a solution (liquid) to spray into the nose. It is usually used every 10 to 12 hours as needed, but not more often than twice in a 24-hour period. Follow the directions on the package label or on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use oxymetazoline nasal spray exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor or directed on the label.

If you use oxymetazoline nasal spray for more often or for longer than the recommended period of time, your congestion may get worse or may improve but come back. Do not use oxymetazoline nasal spray for longer than 3 days. If your symptoms do not get better after 3 days of treatment, stop using oxymetazoline and call your doctor.

Oxymetazoline nasal spray is only for use in the nose. Do not swallow the medication.

To prevent the spread of infection, do not share your spray dispenser with anyone else. Rinse the tip of the dispenser with hot water or wipe it clean after you use it.

Follow the directions for using the nasal spray that appear on the package label. If you are using a product that comes in a pump dispenser, press down on the rim several times before using your first dose to prime the pump, according to the directions on the label. When you are ready to use the spray, hold your head upright without tilting and place the tip of the bottle in your nostril. For the nasal spray, squeeze the bottle quickly and firmly. For products that come in a pump dispenser, press down on the rim with a firm, even stroke and breathe in deeply.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Before using oxymetazoline,

  • tell your doctor and pharmacist if you are allergic to oxymetazoline, or any other medications.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to tell your doctor or pharmacist if you are taking the following medications or have stopped taking them within the past two weeks: isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate).

  • tell your doctor if you have or have ever had high blood pressure, diabetes, difficulty urinating due to an enlarged prostate gland, or thyroid or heart disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using oxymetazoline nasal spray, call your doctor.

Unless your doctor tells you otherwise, continue your normal diet.

This medication is usually used as needed. If your doctor has told you to use oxymetazoline regularly, use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.

  • Oxymetazoline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • burning

    • stinging

    • increased nasal discharge

    • dryness inside the nose

    • sneezing

    • nervousness

    • nausea

    • dizziness

    • headache

    • difficulty falling asleep or staying asleep

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

    • fast heartbeat

    • slow heartbeat

  • Oxymetazoline nasal spray may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat, light, and moisture (not in the bathroom). Do not freeze the medication.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

If you use too much oxymetazoline nasal spray or if someone swallows the medication, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911

Ask your pharmacist any questions you have about oxymetazoline nasal spray.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Aminophylline Aminophylline The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Aminophylline.
Anagrelide Anagrelide The risk or severity of Tachycardia can be increased when Anagrelide is combined with Oxymetazoline.
Candesartan Candesartan Oxymetazoline may decrease the antihypertensive activities of Candesartan.
Cilostazol Cilostazol The risk or severity of Tachycardia can be increased when Oxymetazoline is combined with Cilostazol.
Guanfacine Guanfacine The risk or severity of hypertension can be increased when Oxymetazoline is combined with Guanfacine.
Methylergonovine Methylergonovine Methylergometrine may increase the hypertensive and vasoconstricting activities of Oxymetazoline.
Naratriptan Naratriptan The risk or severity of hypertension can be increased when Oxymetazoline is combined with Naratriptan.
Olsalazine Olsalazine The risk or severity of hypertension can be increased when Oxymetazoline is combined with Olsalazine.
Penbutolol Penbutolol The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Acebutolol.
Sumatriptan Sumatriptan The risk or severity of hypertension can be increased when Sumatriptan is combined with Oxymetazoline.
Tizanidine Tizanidine The risk or severity of adverse effects can be increased when Tizanidine is combined with Oxymetazoline.
Zolmitriptan Zolmitriptan The risk or severity of hypertension can be increased when Zolmitriptan is combined with Oxymetazoline.
Altretamine Altretamine Amphetamine may increase the hypertensive activities of Oxymetazoline.
Cyclosporine Cyclosporine The risk or severity of hypertension can be increased when Cyclosporine is combined with Oxymetazoline.
Torsemide Torsemide Oxymetazoline may decrease the antihypertensive activities of Torasemide.
Olanzapine Olanzapine The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Olanzapine.
Meloxicam Meloxicam The risk or severity of hypertension can be increased when Meloxicam is combined with Oxymetazoline.
Telmisartan Telmisartan Oxymetazoline may decrease the antihypertensive activities of Telmisartan.
Linezolid Linezolid The risk or severity of hypertension can be increased when Linezolid is combined with Oxymetazoline.
Trimipramine Trimipramine Trimipramine may increase the vasopressor activities of Oxymetazoline.
Glycopyrrolate Glycopyrrolate The risk or severity of Tachycardia can be increased when Oxymetazoline is combined with Glycopyrronium.
Perindopril Perindopril Oxymetazoline may decrease the antihypertensive activities of Perindopril.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate The risk or severity of hypertension can be increased when Oxymetazoline is combined with Choline magnesium trisalicylate.
Dutasteride Dutasteride The risk or severity of hypertension can be increased when Oxymetazoline is combined with Dutasteride.
Epinephrine Injection Epinephrine Injection The therapeutic efficacy of Oxymetazoline can be increased when used in combination with Epinephrine.
Eplerenone Eplerenone Oxymetazoline may decrease the antihypertensive activities of Eplerenone.
Olmesartan Olmesartan Oxymetazoline may decrease the antihypertensive activities of Olmesartan.
Atomoxetine Atomoxetine The risk or severity of hypertension can be increased when Atomoxetine is combined with Oxymetazoline.
Dexmethylphenidate Dexmethylphenidate The risk or severity of hypertension can be increased when Oxymetazoline is combined with Dexmethylphenidate.
Teriparatide Injection Teriparatide Injection The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Teriparatide.
Almotriptan Almotriptan The risk or severity of hypertension can be increased when Almotriptan is combined with Oxymetazoline.
Eletriptan Eletriptan The risk or severity of hypertension can be increased when Eletriptan is combined with Oxymetazoline.
Alfuzosin Alfuzosin The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Alfuzosin.
Tadalafil Tadalafil Oxymetazoline may decrease the antihypertensive activities of Tadalafil.
Frovatriptan Frovatriptan The risk or severity of hypertension can be increased when Oxymetazoline is combined with Frovatriptan.
Duloxetine Duloxetine Duloxetine may increase the tachycardic activities of Oxymetazoline.
Trospium Trospium The risk or severity of Tachycardia can be increased when Trospium is combined with Oxymetazoline.
Bosentan Bosentan Oxymetazoline may decrease the antihypertensive activities of Bosentan.
Solifenacin Solifenacin The risk or severity of hypertension can be increased when Oxymetazoline is combined with Solifenacin.
Dextroamphetamine Dextroamphetamine Amphetamine may increase the hypertensive activities of Oxymetazoline.
Isocarboxazid Isocarboxazid Isocarboxazid may increase the hypertensive activities of Oxymetazoline.
Darifenacin Darifenacin The risk or severity of Tachycardia can be increased when Darifenacin is combined with Oxymetazoline.
Fentanyl Fentanyl Oxymetazoline can cause a decrease in the absorption of Fentanyl resulting in a reduced serum concentration and potentially a decrease in efficacy.
Rasagiline Rasagiline Rasagiline may increase the hypertensive activities of Oxymetazoline.
Albuterol Albuterol The risk or severity of hypertension can be increased when Oxymetazoline is combined with Salbutamol.
Paliperidone Paliperidone The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Paliperidone.
Aliskiren Aliskiren Oxymetazoline may decrease the antihypertensive activities of Aliskiren.
Lisdexamfetamine Lisdexamfetamine The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Lisdexamfetamine.
Nabilone Nabilone The risk or severity of Tachycardia can be increased when Nabilone is combined with Oxymetazoline.
Dronabinol Dronabinol The risk or severity of Tachycardia can be increased when Dronabinol is combined with Oxymetazoline.
Desmopressin Desmopressin The risk or severity of hypertension can be increased when Desmopressin is combined with Oxymetazoline.
Desvenlafaxine Desvenlafaxine Desvenlafaxine may increase the tachycardic activities of Oxymetazoline.
Nebivolol Nebivolol The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Nebivolol.
Silodosin Silodosin The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Silodosin.
Milnacipran Milnacipran Milnacipran may increase the tachycardic activities of Oxymetazoline.
Betaxolol Betaxolol The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Betaxolol.
Iloperidone Iloperidone The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Iloperidone.
Dronedarone Dronedarone The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Dronedarone.
Lurasidone Lurasidone The risk or severity of hypertension can be increased when Oxymetazoline is combined with Lurasidone.
Vilazodone Vilazodone The risk or severity of hypertension can be increased when Oxymetazoline is combined with Vilazodone.
Terbutaline Injection Terbutaline Injection The risk or severity of adverse effects can be increased when Terbutaline is combined with Oxymetazoline.
Cabergoline Cabergoline Cabergoline may increase the hypertensive and vasoconstricting activities of Oxymetazoline.
Ambrisentan Ambrisentan Oxymetazoline may decrease the antihypertensive activities of Ambrisentan.
Mirabegron Mirabegron The risk or severity of hypertension can be increased when Oxymetazoline is combined with Mirabegron.
Levomilnacipran Levomilnacipran Levomilnacipran may increase the tachycardic activities of Oxymetazoline.
Vortioxetine Vortioxetine The risk or severity of hypertension can be increased when Oxymetazoline is combined with Vortioxetine.
Ketorolac Injection Ketorolac Injection The risk or severity of hypertension can be increased when Ketorolac is combined with Oxymetazoline.
Droxidopa Droxidopa The therapeutic efficacy of Oxymetazoline can be increased when used in combination with Droxidopa.
Methamphetamine Methamphetamine The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Metamfetamine.
Riociguat Riociguat Oxymetazoline may decrease the antihypertensive activities of Riociguat.
Risperidone Injection Risperidone Injection The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Risperidone.
Macitentan Macitentan Oxymetazoline may decrease the antihypertensive activities of Macitentan.
Flibanserin Flibanserin The risk or severity of hypertension can be increased when Oxymetazoline is combined with Flibanserin.
Brexpiprazole Brexpiprazole The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Ziprasidone.
Cariprazine Cariprazine The risk or severity of hypertension can be increased when Oxymetazoline is combined with Cariprazine.
Midodrine Midodrine The risk or severity of adverse effects can be increased when Midodrine is combined with Oxymetazoline.
Selexipag Selexipag Oxymetazoline may decrease the antihypertensive activities of Selexipag.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of Tachycardia can be increased when Oxymetazoline is combined with Diphenhydramine.
Furosemide Injection Furosemide Injection Oxymetazoline may decrease the antihypertensive activities of Furosemide.
Parathyroid Hormone Injection Parathyroid Hormone Injection The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Parathyroid hormone.
Doxepin (Insomnia) Doxepin (Insomnia) Doxepin may increase the vasopressor activities of Oxymetazoline.
Safinamide Safinamide Safinamide may increase the hypertensive activities of Oxymetazoline.
Abaloparatide Injection Abaloparatide Injection The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Abaloparatide.
Lofexidine Lofexidine The risk or severity of hypertension can be increased when Oxymetazoline is combined with Lofexidine.
Cannabidiol Cannabidiol The risk or severity of Tachycardia can be increased when Cannabidiol is combined with Oxymetazoline.
Siponimod Siponimod The risk or severity of hypertension can be increased when Oxymetazoline is combined with Siponimod.
Solriamfetol Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Oxymetazoline.
Selpercatinib Selpercatinib The risk or severity of hypertension can be increased when Oxymetazoline is combined with Selpercatinib.
Daratumumab and Hyaluronidase-fihj Injection Daratumumab and Hyaluronidase-fihj Injection The risk or severity of adverse effects can be increased when Hyaluronidase is combined with Oxymetazoline.
Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf Injection Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf Injection The risk or severity of adverse effects can be increased when Hyaluronidase is combined with Oxymetazoline.
Naxitamab-gqgk Injection Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Oxymetazoline is combined with Naxitamab.
Theophylline Theophylline The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Theophylline.
Fenoprofen Fenoprofen The risk or severity of hypertension can be increased when Fenoprofen is combined with Oxymetazoline.
Indomethacin Indomethacin The risk or severity of hypertension can be increased when Indomethacin is combined with Oxymetazoline.
Mefenamic Acid Mefenamic Acid The risk or severity of hypertension can be increased when Mefenamic acid is combined with Oxymetazoline.
Naproxen Naproxen The risk or severity of hypertension can be increased when Naproxen is combined with Oxymetazoline.
Tolmetin Tolmetin The risk or severity of hypertension can be increased when Tolmetin is combined with Oxymetazoline.
Sulindac Sulindac The risk or severity of hypertension can be increased when Sulindac is combined with Oxymetazoline.
Trazodone Trazodone The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Trazodone.
Diethylpropion Diethylpropion The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Diethylpropion.
Chlorpromazine Chlorpromazine The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Chlorpromazine.
Bromocriptine Bromocriptine Bromocriptine may increase the hypertensive and vasoconstricting activities of Oxymetazoline.
Metaproterenol Metaproterenol The risk or severity of adverse effects can be increased when Orciprenaline is combined with Oxymetazoline.
Tranylcypromine Tranylcypromine Tranylcypromine may increase the hypertensive activities of Oxymetazoline.
Ergoloid Mesylates Ergoloid Mesylates Ergoloid mesylate may increase the hypertensive and vasoconstricting activities of Oxymetazoline.
Thioridazine Thioridazine The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Thioridazine.
Trifluoperazine Trifluoperazine The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Trifluoperazine.
Oxybutynin Oxybutynin The risk or severity of Tachycardia can be increased when Oxymetazoline is combined with Oxybutynin.
Benztropine Benztropine The risk or severity of Tachycardia can be increased when Benzatropine is combined with Oxymetazoline.
Maprotiline Maprotiline The risk or severity of Tachycardia can be increased when Maprotiline is combined with Oxymetazoline.
Ibuprofen Ibuprofen The risk or severity of hypertension can be increased when Oxymetazoline is combined with Ibuprofen.
Trihexyphenidyl Trihexyphenidyl The risk or severity of Tachycardia can be increased when Trihexyphenidyl is combined with Oxymetazoline.
Orphenadrine Orphenadrine The risk or severity of Tachycardia can be increased when Oxymetazoline is combined with Orphenadrine.
Methylphenidate Methylphenidate The risk or severity of hypertension can be increased when Methylphenidate is combined with Oxymetazoline.
Amoxapine Amoxapine Amoxapine may increase the vasopressor activities of Oxymetazoline.
Methyldopa Methyldopa Oxymetazoline may decrease the antihypertensive activities of Methyldopa.
Clonidine Clonidine The risk or severity of hypertension can be increased when Clonidine is combined with Oxymetazoline.
Hydralazine Hydralazine Oxymetazoline may decrease the antihypertensive activities of Hydralazine.
Meclofenamate Meclofenamate The risk or severity of hypertension can be increased when Oxymetazoline is combined with Meclofenamic acid.
Chlorothiazide Chlorothiazide Oxymetazoline may decrease the antihypertensive activities of Chlorothiazide.
Chlorthalidone Chlorthalidone Oxymetazoline may decrease the antihypertensive activities of Chlorthalidone.
Metolazone Metolazone Oxymetazoline may decrease the antihypertensive activities of Metolazone.
Desipramine Desipramine Desipramine may increase the vasopressor activities of Oxymetazoline.
Amitriptyline Amitriptyline Amitriptyline may increase the vasopressor activities of Oxymetazoline.
Imipramine Imipramine Imipramine may increase the vasopressor activities of Oxymetazoline.
Disopyramide Disopyramide The risk or severity of Tachycardia can be increased when Disopyramide is combined with Oxymetazoline.
Levothyroxine Levothyroxine The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Levothyroxine.
Liothyronine Liothyronine The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Liothyronine.
Methimazole Methimazole The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Methimazole.
Doxylamine Doxylamine The risk or severity of Tachycardia can be increased when Doxylamine is combined with Oxymetazoline.
Cyproheptadine Cyproheptadine The risk or severity of Tachycardia can be increased when Cyproheptadine is combined with Oxymetazoline.
Brompheniramine Brompheniramine The risk or severity of Tachycardia can be increased when Brompheniramine is combined with Oxymetazoline.
Hydrochlorothiazide Hydrochlorothiazide Oxymetazoline may decrease the antihypertensive activities of Hydrochlorothiazide.
Minoxidil Minoxidil Oxymetazoline may decrease the antihypertensive activities of Minoxidil.
Nortriptyline Nortriptyline Nortriptyline may increase the vasopressor activities of Oxymetazoline.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Mercaptopurine.
Nadolol Nadolol The risk or severity of hypertension can be increased when Nadolol is combined with Oxymetazoline.
Flavoxate Flavoxate The risk or severity of Tachycardia can be increased when Oxymetazoline is combined with Flavoxate.
Calcitonin Salmon Injection Calcitonin Salmon Injection The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Salmon calcitonin.
Captopril Captopril Oxymetazoline may decrease the antihypertensive activities of Captopril.
Isoxsuprine Isoxsuprine The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Isoxsuprine.
Metoprolol Metoprolol The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Metoprolol.
Aspirin Aspirin The risk or severity of hypertension can be increased when Oxymetazoline is combined with Acetylsalicylic acid.
Salsalate Salsalate The risk or severity of hypertension can be increased when Oxymetazoline is combined with Salsalate.
Dicyclomine Dicyclomine The risk or severity of Tachycardia can be increased when Dicyclomine is combined with Oxymetazoline.
Hyoscyamine Hyoscyamine The risk or severity of Tachycardia can be increased when Hyoscyamine is combined with Oxymetazoline.
Diltiazem Diltiazem Oxymetazoline may decrease the antihypertensive activities of Diltiazem.
Timolol Timolol The risk or severity of hypertension can be increased when Timolol is combined with Oxymetazoline.
Verapamil Verapamil The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Verapamil.
Atenolol Atenolol The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Atenolol.
Diflunisal Diflunisal The risk or severity of hypertension can be increased when Diflunisal is combined with Oxymetazoline.
Glyburide Glyburide The therapeutic efficacy of Glyburide can be decreased when used in combination with Oxymetazoline.
Indapamide Indapamide Oxymetazoline may decrease the antihypertensive activities of Indapamide.
Labetalol Labetalol The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Labetalol.
Guanabenz Guanabenz The risk or severity of hypertension can be increased when Guanabenz is combined with Oxymetazoline.
Ketoprofen Ketoprofen The risk or severity of hypertension can be increased when Oxymetazoline is combined with Ketoprofen.
Enalapril Enalapril Oxymetazoline may decrease the antihypertensive activities of Enalapril.
Flurbiprofen Flurbiprofen The risk or severity of hypertension can be increased when Flurbiprofen is combined with Oxymetazoline.
Buspirone Buspirone The risk or severity of hypertension can be increased when Buspirone is combined with Oxymetazoline.
Mesalamine Mesalamine The risk or severity of hypertension can be increased when Mesalazine is combined with Oxymetazoline.
Diclofenac Diclofenac The risk or severity of hypertension can be increased when Diclofenac is combined with Oxymetazoline.
Nimodipine Nimodipine Oxymetazoline may decrease the antihypertensive activities of Nimodipine.
Clozapine Clozapine The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Clozapine.
Benazepril Benazepril Oxymetazoline may decrease the antihypertensive activities of Benazepril.
Etodolac Etodolac The risk or severity of hypertension can be increased when Etodolac is combined with Oxymetazoline.
Felodipine Felodipine Felodipine may decrease the antihypertensive activities of Oxymetazoline.
Fosinopril Fosinopril Oxymetazoline may decrease the antihypertensive activities of Fosinopril.
Nabumetone Nabumetone The risk or severity of hypertension can be increased when Nabumetone is combined with Oxymetazoline.
Quinapril Quinapril Oxymetazoline may decrease the antihypertensive activities of Quinapril.
Ramipril Ramipril Oxymetazoline may decrease the antihypertensive activities of Ramipril.
Amlodipine Amlodipine Oxymetazoline may decrease the antihypertensive activities of Amlodipine.
Lisinopril Lisinopril Oxymetazoline may decrease the antihypertensive activities of Lisinopril.
Oxaprozin Oxaprozin The risk or severity of hypertension can be increased when Oxymetazoline is combined with Oxaprozin.
Bisoprolol Bisoprolol The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Bisoprolol.
Doxazosin Doxazosin The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Doxazosin.
Terazosin Terazosin The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Terazosin.
Isradipine Isradipine Oxymetazoline may decrease the antihypertensive activities of Isradipine.
Venlafaxine Venlafaxine Venlafaxine may increase the tachycardic activities of Oxymetazoline.
Nefazodone Nefazodone The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Nefazodone.
Lamotrigine Lamotrigine The risk or severity of Tachycardia can be increased when Lamotrigine is combined with Oxymetazoline.
Losartan Losartan Oxymetazoline may decrease the antihypertensive activities of Losartan.
Tramadol Tramadol The risk or severity of Tachycardia can be increased when Tramadol is combined with Oxymetazoline.
Moexipril Moexipril Oxymetazoline may decrease the antihypertensive activities of Moexipril.
Nicardipine Nicardipine The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Nicardipine.
Nisoldipine Nisoldipine Oxymetazoline may decrease the antihypertensive activities of Nisoldipine.
Clomipramine Clomipramine Clomipramine may increase the vasopressor activities of Oxymetazoline.
Mirtazapine Mirtazapine Mirtazapine may decrease the antihypertensive activities of Oxymetazoline.
Trandolapril Trandolapril Oxymetazoline may decrease the antihypertensive activities of Trandolapril.
Valsartan Valsartan Oxymetazoline may decrease the antihypertensive activities of Valsartan.
Carvedilol Carvedilol The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Carvedilol.
Tamsulosin Tamsulosin The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Tamsulosin.
Finasteride Finasteride The risk or severity of hypertension can be increased when Oxymetazoline is combined with Finasteride.
Quetiapine Quetiapine The therapeutic efficacy of Oxymetazoline can be decreased when used in combination with Quetiapine.
Paroxetine Paroxetine The risk or severity of Tachycardia can be increased when Paroxetine is combined with Oxymetazoline.
Celecoxib Celecoxib The risk or severity of hypertension can be increased when Celecoxib is combined with Oxymetazoline.
Tolterodine Tolterodine The risk or severity of Tachycardia can be increased when Oxymetazoline is combined with Tolterodine.
Balsalazide Balsalazide The risk or severity of hypertension can be increased when Oxymetazoline is combined with Balsalazide.

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