Rizatriptan

Generic name: Pronounced as (rye za trip' tan)
Brand names
  • Maxalt-MLT®
  • Maxalt®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 01/15/2022

Rizatriptan is used to treat the symptoms of migraine headaches (severe, throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound and light). Rizatriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and blocking the release of certain natural substances that cause pain, nausea, and other symptoms of migraine. Rizatriptan does not prevent migraine attacks or reduce the number of headaches you have.

Rizatriptan comes as a tablet and an orally disintegrating tablet to take by mouth. It is usually taken at the first sign of a migraine headache. If your symptoms improve after you take rizatriptan but return after 2 hours or longer, you may take a second tablet. However, if your symptoms do not improve after you take rizatriptan, do not take a second tablet before calling your doctor. Your doctor will tell you the maximum number of tablets you may take in a 24-hour period. Follow the directions on the package or prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take rizatriptan exactly as directed. Do not take more or less of it or take it more often than directed by the package label or prescribed by your doctor.

You may take your first dose of rizatriptan in a doctor's office or other medical facility where you can be monitored for serious reactions.

To take the orally disintegrating tablet, use dry hands to peel back the foil packaging.Immediately take out the tablet and place it on your tongue.The tablet will quickly dissolve and can be swallowed with saliva. No water is needed to swallow disintegrating tablets. Do not open the foil packaging or remove the orally disintegrating tablet until just before your are ready to take it.

Call your doctor if your headaches do not get better or occur more frequently after taking rizatriptan.

If you take rizatriptan more often or for longer than the recommended period of time, your headaches may get worse or may occur more frequently. You should not take rizatriptan or any other headache medication for more than 10 days per month. Call your doctor if you need to take rizatriptan to treat more than four headaches in a 1-month period.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking rizatriptan

  • tell your doctor and pharmacist if you are allergic to rizatriptan, any other medications, or any of the ingredients in rizatriptan tablets or orally disintegrating tablets. Ask your pharmacist for a list of the ingredients.

  • do not take rizatriptan if you have taken any of the following medications in the past 24 hours: other selective serotonin receptor agonists such as almotriptan (Axert), eletriptan (Relpax), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, in Treximet), or zolmitriptan (Zomig); or ergot-type medications such as bromocriptine (Parlodel), cabergoline, dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Hydergine), ergonovine (Ergotrate), ergotamine (Cafergot, Ergomar), methylergonovine (Methergine), methysergide (Sansert), and pergolide (Permax).

  • do not take rizatriptan if you are taking a monoamine oxidase A (MAO-A) inhibitor such as isocarboxazid (Marplan), phenelzine (Parnate), or tranylcypromine (Nardil) or if you have taken one of these medications in the past 2 weeks.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, or herbal products you are taking or plan to take. Be sure to mention any of the following: acetaminophen (Tylenol); antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); propranolol (Inderal); selective serotonin reuptake inhibitors such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine, paroxetine (Paxil), and sertraline (Zoloft); and selective serotonin/norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Pristiq), duloxetine (Cymbalta), sibutramine (Meridia), and venlafaxine (Effexor). Your doctor may need to change the doses of your medications or monitor you more carefully for side effects.

  • tell your doctor if you have or have ever had heart disease; a heart attack; angina (chest pain); irregular heartbeats; stroke or 'mini-stroke'; or circulation problems such as varicose veins, blood clots in the legs, Raynaud's disease (problems with blood flow to the fingers, toes, ears, and nose), or ischemic bowel disease (bloody diarrhea and stomach pain caused by decreased blood flow to the intestines). Your doctor may tell you not to take rizatriptan.

  • tell your doctor if you smoke or are overweight; if you have or have ever had high blood pressure, diabetes, high cholesterol, or kidney or liver disease; if you have gone through menopause (change of life); or if any family members have or have ever had heart disease or stroke.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you plan to be sexually active while you are taking this medication, talk to your doctor about effective methods of birth control. If you become pregnant while taking rizatriptan, call your doctor.

  • you should know that rizatriptan may make you drowsy. Do not drive a car or operate machinery until you know how this medication will affect you.

  • talk to your doctor about your headache symptoms to make sure they are caused by migraine. Rizatriptan should not be used to treat hemiplegic or basilar migraine or headaches caused by other conditions (such as cluster headaches).

  • if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent damage to your brain that can cause severe intellectual disability), you should know that the orally disintegrating tablets contain aspartame that forms phenylalanine.

Unless your doctor tells you otherwise, continue your normal diet.

  • Rizatriptan may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • drowsiness

    • dizziness

    • tiredness

    • upset stomach

    • vomiting

    • diarrhea

    • muscle pain or cramps

    • tremors

    • flushing (feeling of warmth)

    • dry mouth

  • Some side effects can be serious. If you experience any of these, call your doctor immediately or get emergency medical treatment:

    • tightness, pain, pressure, or heaviness in the chest, throat, neck, or jaw

    • rapid, pounding, or irregular heartbeat

    • shortness of breath

    • breaking out in a cold sweat

    • lightheadedness

    • slow or difficult speech

    • weakness or numbness of an arm or leg

    • sudden or severe stomach pain

    • bloody diarrhea

    • paleness or blue color of the fingers and toes

    • pain, burning, or tingling in the hands or feet

    • difficulty breathing or swallowing

    • swelling of the face, throat, tongue, lips, lips, eyes, hands, feet, ankles, or lower legs

    • rash

    • itching

    • changes in vision

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Do not remove tablets from the blister pack until just before use. Store the medication at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

  • drowsiness

  • dizziness or faintness

  • tightness, pain, pressure, or heaviness in the chest, throat, neck, and/or jaw

  • rapid, pounding, or irregular heart beat

  • shortness of breath

  • vomiting

  • headache

Keep all appointments with your doctor. Your blood pressure should be checked regularly.

You should keep a headache diary by writing down when you have headaches and when you take rizatriptan.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Dolasetron Dolasetron The risk or severity of adverse effects can be increased when Dolasetron is combined with Rizatriptan.
Candesartan Candesartan Rizatriptan may decrease the antihypertensive activities of Candesartan.
Cilostazol Cilostazol Rizatriptan may decrease the excretion rate of Cilostazol which could result in a higher serum level.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Rizatriptan is combined with Diphenoxylate.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Conjugated estrogens may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Fenofibrate Fenofibrate Rizatriptan may decrease the excretion rate of Fenofibrate which could result in a higher serum level.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Guanfacine.
Magnesium Hydroxide Magnesium Hydroxide Rizatriptan may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Methylergonovine Methylergonovine Methylergometrine may increase the vasoconstricting activities of Rizatriptan.
Mycophenolate Mycophenolate Rizatriptan may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level.
Naratriptan Naratriptan The risk or severity of adverse effects can be increased when Naratriptan is combined with Rizatriptan.
Olsalazine Olsalazine Olsalazine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Rizatriptan.
Penbutolol Penbutolol Rizatriptan may decrease the antihypertensive activities of Acebutolol.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Rizatriptan.
Potassium Potassium Potassium may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone Prednisone Prednisone may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Ranitidine Ranitidine Ranitidine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Reserpine Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Sumatriptan is combined with Rizatriptan.
Tacrolimus Tacrolimus Tacrolimus may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Tizanidine Tizanidine The risk or severity of adverse effects can be increased when Tizanidine is combined with Rizatriptan.
Zolmitriptan Zolmitriptan The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Rizatriptan.
Ampicillin Injection Ampicillin Injection Ampicillin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection Doxycycline may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Fluconazole Injection Fluconazole Injection Fluconazole may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Foscarnet Injection Foscarnet Injection Foscarnet may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Hydromorphone Injection Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Rizatriptan.
Levofloxacin Injection Levofloxacin Injection Rizatriptan may decrease the excretion rate of Levofloxacin which could result in a higher serum level.
Meperidine Injection Meperidine Injection The risk or severity of adverse effects can be increased when Meperidine is combined with Rizatriptan.
Metoclopramide Injection Metoclopramide Injection The risk or severity of sedation can be increased when Rizatriptan is combined with Metoclopramide.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Rizatriptan.
Pamidronate Injection Pamidronate Injection Pamidronic acid may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Vancomycin Injection Vancomycin Injection Rizatriptan may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Altretamine Altretamine The metabolism of Rizatriptan can be decreased when combined with Amphetamine.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Cyclosporine Cyclosporine Cyclosporine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Ondansetron Ondansetron The risk or severity of adverse effects can be increased when Ondansetron is combined with Rizatriptan.
Granisetron Granisetron The risk or severity of adverse effects can be increased when Granisetron is combined with Rizatriptan.
Torsemide Torsemide Torasemide may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Olanzapine Olanzapine The risk or severity of adverse effects can be increased when Olanzapine is combined with Rizatriptan.
Alosetron Alosetron The risk or severity of adverse effects can be increased when Rizatriptan is combined with Alosetron.
Entacapone Entacapone The risk or severity of adverse effects can be increased when Entacapone is combined with Rizatriptan.
Eprosartan Eprosartan Rizatriptan may decrease the antihypertensive activities of Eprosartan.
Meloxicam Meloxicam Meloxicam may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Oxcarbazepine Oxcarbazepine The risk or severity of adverse effects can be increased when Oxcarbazepine is combined with Rizatriptan.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Telmisartan Telmisartan Rizatriptan may decrease the antihypertensive activities of Telmisartan.
Temozolomide Temozolomide Temozolomide may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Zaleplon Zaleplon Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Zaleplon.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Desloratadine.
Linezolid Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Rizatriptan.
Trimipramine Trimipramine The risk or severity of adverse effects can be increased when Trimipramine is combined with Rizatriptan.
Glycopyrrolate Glycopyrrolate Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Perindopril Perindopril Perindopril may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Tenofovir Tenofovir Tenofovir may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Dutasteride Dutasteride The risk or severity of hypertension can be increased when Rizatriptan is combined with Dutasteride.
Epinephrine Injection Epinephrine Injection The risk or severity of hypertension can be increased when Epinephrine is combined with Rizatriptan.
Eplerenone Eplerenone Eplerenone may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Escitalopram Escitalopram The risk or severity of serotonin syndrome can be increased when Rizatriptan is combined with Escitalopram.
Olmesartan Olmesartan Rizatriptan may decrease the antihypertensive activities of Olmesartan.
Zonisamide Zonisamide The metabolism of Rizatriptan can be decreased when combined with Zonisamide.
Aripiprazole Aripiprazole The risk or severity of adverse effects can be increased when Rizatriptan is combined with Aripiprazole.
Atomoxetine Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Rizatriptan.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Rizatriptan is combined with Dexmethylphenidate.
Atazanavir Atazanavir Atazanavir may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Almotriptan Almotriptan The risk or severity of adverse effects can be increased when Almotriptan is combined with Rizatriptan.
Eletriptan Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Rizatriptan.
Emtricitabine Emtricitabine Emtricitabine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Memantine Memantine Rizatriptan may decrease the excretion rate of Memantine which could result in a higher serum level.
Tegaserod Tegaserod The risk or severity of serotonin syndrome can be increased when Rizatriptan is combined with Tegaserod.
Tadalafil Tadalafil Tadalafil may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Frovatriptan Frovatriptan The risk or severity of adverse effects can be increased when Rizatriptan is combined with Frovatriptan.
Apomorphine Injection Apomorphine Injection The risk or severity of adverse effects can be increased when Apomorphine is combined with Rizatriptan.
Protriptyline Protriptyline The risk or severity of adverse effects can be increased when Protriptyline is combined with Rizatriptan.
Duloxetine Duloxetine The risk or severity of adverse effects can be increased when Duloxetine is combined with Rizatriptan.
Tinidazole Tinidazole Tinidazole may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Trospium Trospium Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Bosentan Bosentan Rizatriptan may decrease the antihypertensive activities of Bosentan.
Cefditoren Cefditoren Cefdinir may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Cyanocobalamin Injection Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Rizatriptan is combined with Eszopiclone.
Ganciclovir Ganciclovir Rizatriptan may decrease the excretion rate of Ganciclovir which could result in a higher serum level.
Ribavirin Ribavirin Ribavirin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Solifenacin Solifenacin Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Valganciclovir Valganciclovir Rizatriptan may decrease the excretion rate of Valganciclovir which could result in a higher serum level.
Adefovir Adefovir Adefovir may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine The metabolism of Rizatriptan can be decreased when combined with Amphetamine.
Sodium Oxybate Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Isocarboxazid Isocarboxazid The metabolism of Rizatriptan can be decreased when combined with Isocarboxazid.
Ramelteon Ramelteon The risk or severity of adverse effects can be increased when Rizatriptan is combined with Ramelteon.
Darifenacin Darifenacin Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Darifenacin.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Fentanyl is combined with Rizatriptan.
Pregabalin Pregabalin The therapeutic efficacy of Rizatriptan can be increased when used in combination with Pregabalin.
Phenylephrine Phenylephrine The risk or severity of hypertension can be increased when Phenylephrine is combined with Rizatriptan.
Felbamate Felbamate The risk or severity of adverse effects can be increased when Felbamate is combined with Rizatriptan.
Ranolazine Ranolazine Ranolazine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Rasagiline Rasagiline The metabolism of Rizatriptan can be decreased when combined with Rasagiline.
Sitagliptin Sitagliptin Rizatriptan may decrease the excretion rate of Sitagliptin which could result in a higher serum level.
Varenicline Varenicline Rizatriptan may decrease the excretion rate of Varenicline which could result in a higher serum level.
Albuterol Albuterol Rizatriptan may decrease the excretion rate of Salbutamol which could result in a higher serum level.
Paliperidone Paliperidone The risk or severity of adverse effects can be increased when Rizatriptan is combined with Paliperidone.
Clofarabine Injection Clofarabine Injection Clofarabine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Lubiprostone Lubiprostone Rizatriptan may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
Aliskiren Aliskiren Rizatriptan may decrease the antihypertensive activities of Aliskiren.
Pemetrexed Injection Pemetrexed Injection Rizatriptan may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Dimenhydrinate Dimenhydrinate The risk or severity of adverse effects can be increased when Rizatriptan is combined with Dimenhydrinate.
Lisdexamfetamine Lisdexamfetamine The risk or severity of serotonin syndrome can be increased when Rizatriptan is combined with Lisdexamfetamine.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Sorafenib Sorafenib Sorafenib may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Levocetirizine.
Pegaptanib Injection Pegaptanib Injection Rizatriptan may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Azacitidine Injection Azacitidine Injection Azacitidine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Lenalidomide Lenalidomide Lenalidomide may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Budesonide Budesonide Rizatriptan may decrease the excretion rate of Budesonide which could result in a higher serum level.
Desmopressin Desmopressin Desmopressin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Rizatriptan.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Rizatriptan.
Doripenem Injection Doripenem Injection Rizatriptan may decrease the excretion rate of Doripenem which could result in a higher serum level.
Arsenic Trioxide Injection Arsenic Trioxide Injection Rizatriptan may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level.
Desvenlafaxine Desvenlafaxine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Desvenlafaxine.
Cevimeline Cevimeline Cevimeline may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Nebivolol Nebivolol Rizatriptan may decrease the antihypertensive activities of Nebivolol.
Certolizumab Injection Certolizumab Injection Rizatriptan may decrease the excretion rate of Certolizumab pegol which could result in a higher serum level.
Daptomycin Injection Daptomycin Injection Daptomycin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Methylnaltrexone Injection Methylnaltrexone Injection Rizatriptan may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Rizatriptan.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Midazolam is combined with Rizatriptan.
Naltrexone Injection Naltrexone Injection The risk or severity of serotonin syndrome can be increased when Naltrexone is combined with Rizatriptan.
Dexrazoxane Injection Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Milnacipran Milnacipran The risk or severity of adverse effects can be increased when Rizatriptan is combined with Milnacipran.
Plerixafor Injection Plerixafor Injection Rizatriptan may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Fesoterodine Fesoterodine Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Betaxolol Betaxolol Rizatriptan may decrease the antihypertensive activities of Betaxolol.
Iloperidone Iloperidone The risk or severity of adverse effects can be increased when Rizatriptan is combined with Iloperidone.
Prasugrel Prasugrel Rizatriptan may decrease the excretion rate of Prasugrel which could result in a higher serum level.
Lacosamide Lacosamide The risk or severity of adverse effects can be increased when Rizatriptan is combined with Lacosamide.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) Tolvaptan may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Dronedarone Dronedarone The risk or severity of hypertension can be increased when Rizatriptan is combined with Dronedarone.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Rizatriptan.
Pralatrexate Injection Pralatrexate Injection Rizatriptan may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection The risk or severity of adverse effects can be increased when Palonosetron is combined with Rizatriptan.
Saxagliptin Saxagliptin Rizatriptan may decrease the excretion rate of Saxagliptin which could result in a higher serum level.
Telavancin Injection Telavancin Injection Rizatriptan may decrease the excretion rate of Telavancin which could result in a higher serum level.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Topotecan Topotecan Rizatriptan may decrease the excretion rate of Topotecan which could result in a higher serum level.
Asenapine Asenapine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Asenapine.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Rizatriptan is combined with Vigabatrin.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Rizatriptan is combined with Oxymorphone.
Dalfampridine Dalfampridine Rizatriptan may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Rizatriptan.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Lurasidone Lurasidone The risk or severity of adverse effects can be increased when Rizatriptan is combined with Lurasidone.
Acetaminophen Injection Acetaminophen Injection Acetaminophen may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Vilazodone Vilazodone The risk or severity of adverse effects can be increased when Rizatriptan is combined with Vilazodone.
Ipilimumab Injection Ipilimumab Injection Rizatriptan may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Terbutaline Injection Terbutaline Injection Terbutaline may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Roflumilast Roflumilast Rizatriptan may decrease the excretion rate of Roflumilast which could result in a higher serum level.
Rivaroxaban Rivaroxaban Rizatriptan may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ruxolitinib Ruxolitinib Rizatriptan may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Clobazam Clobazam The risk or severity of adverse effects can be increased when Clobazam is combined with Rizatriptan.
Deferiprone Deferiprone Rizatriptan may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Cabergoline Cabergoline Cabergoline may increase the vasoconstricting activities of Rizatriptan.
Naloxone Injection Naloxone Injection Rizatriptan may decrease the excretion rate of Naloxone which could result in a higher serum level.
Ambrisentan Ambrisentan Rizatriptan may decrease the antihypertensive activities of Ambrisentan.
Fondaparinux Injection Fondaparinux Injection Fondaparinux may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Tiagabine is combined with Rizatriptan.
Enzalutamide Enzalutamide Rizatriptan may decrease the excretion rate of Enzalutamide which could result in a higher serum level.
Mirabegron Mirabegron Rizatriptan may decrease the excretion rate of Mirabegron which could result in a higher serum level.
Teduglutide Injection Teduglutide Injection Rizatriptan may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Alogliptin Alogliptin Rizatriptan may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Rizatriptan is combined with Pomalidomide.
Canagliflozin Canagliflozin Rizatriptan may increase the excretion rate of Canagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Trametinib Trametinib Rizatriptan may decrease the excretion rate of Trametinib which could result in a higher serum level.
Levomilnacipran Levomilnacipran The risk or severity of adverse effects can be increased when Rizatriptan is combined with Levomilnacipran.
Ertapenem Injection Ertapenem Injection Ertapenem may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Vortioxetine Vortioxetine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Vortioxetine.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Ketorolac Injection Ketorolac Injection Ketorolac may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Sofosbuvir Sofosbuvir Rizatriptan may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin Dapagliflozin may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Apremilast Apremilast Rizatriptan may decrease the excretion rate of Apremilast which could result in a higher serum level.
Droxidopa Droxidopa Rizatriptan may increase the hypertensive activities of Droxidopa.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Eslicarbazepine.
Testosterone Injection Testosterone Injection Testosterone may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Hydrocodone Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Suvorexant Suvorexant Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Edoxaban Edoxaban Rizatriptan may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Methamphetamine Methamphetamine The metabolism of Rizatriptan can be decreased when combined with Metamfetamine.
Tasimelteon Tasimelteon The risk or severity of adverse effects can be increased when Rizatriptan is combined with Tasimelteon.
Riociguat Riociguat Rizatriptan may decrease the antihypertensive activities of Riociguat.
Risperidone Injection Risperidone Injection The risk or severity of adverse effects can be increased when Risperidone is combined with Rizatriptan.
Haloperidol Injection Haloperidol Injection The risk or severity of CNS depression can be increased when Haloperidol is combined with Rizatriptan.
Amiloride Amiloride Amiloride may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Macitentan Macitentan Rizatriptan may decrease the excretion rate of Macitentan which could result in a higher serum level.
Flibanserin Flibanserin The risk or severity of adverse effects can be increased when Rizatriptan is combined with Flibanserin.
Brexpiprazole Brexpiprazole The risk or severity of adverse effects can be increased when Rizatriptan is combined with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of adverse effects can be increased when Ziprasidone is combined with Rizatriptan.
Cariprazine Cariprazine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Cariprazine.
Penicillin G Procaine Injection Penicillin G Procaine Injection Rizatriptan may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Eluxadoline Eluxadoline The risk or severity of serotonin syndrome can be increased when Rizatriptan is combined with Eluxadoline.
Ixazomib Ixazomib Rizatriptan may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lesinurad Lesinurad Rizatriptan may decrease the excretion rate of Lesinurad which could result in a higher serum level.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Brivaracetam Injection Brivaracetam Injection The risk or severity of adverse effects can be increased when Rizatriptan is combined with Brivaracetam.
Midodrine Midodrine The risk or severity of hypertension can be increased when Midodrine is combined with Rizatriptan.
Selexipag Selexipag Rizatriptan may decrease the antihypertensive activities of Selexipag.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Rizatriptan is combined with Pimavanserin.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of adverse effects can be increased when Rizatriptan is combined with Diphenhydramine.
Furosemide Injection Furosemide Injection Furosemide may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Lixisenatide Injection Lixisenatide Injection Rizatriptan may decrease the excretion rate of Lixisenatide which could result in a higher serum level.
Doxepin (Insomnia) Doxepin (Insomnia) Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Doxepin.
Deutetrabenazine Deutetrabenazine Rizatriptan may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level.
Valbenazine Valbenazine Rizatriptan may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Safinamide Safinamide The metabolism of Rizatriptan can be decreased when combined with Safinamide.
Naldemedine Naldemedine Rizatriptan may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Benznidazole Benznidazole Rizatriptan may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Delafloxacin Delafloxacin Rizatriptan may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Ertugliflozin Ertugliflozin Ertugliflozin may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Buprenorphine Injection Buprenorphine Injection Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Apalutamide Apalutamide Rizatriptan may decrease the excretion rate of Apalutamide which could result in a higher serum level.
Baricitinib Baricitinib Rizatriptan may decrease the excretion rate of Baricitinib which could result in a higher serum level.
Lofexidine Lofexidine The therapeutic efficacy of Rizatriptan can be increased when used in combination with Lofexidine.
Plazomicin Injection Plazomicin Injection Rizatriptan may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Cannabidiol Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Rizatriptan.
Stiripentol Stiripentol The risk or severity of adverse effects can be increased when Rizatriptan is combined with Stiripentol.
Gilteritinib Gilteritinib The therapeutic efficacy of Rizatriptan can be decreased when used in combination with Gilteritinib.
Prucalopride Prucalopride Rizatriptan may decrease the excretion rate of Prucalopride which could result in a higher serum level.
Siponimod Siponimod The risk or severity of hypertension can be increased when Rizatriptan is combined with Siponimod.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Rizatriptan is combined with Brexanolone.
Solriamfetol Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Rizatriptan.
Pitolisant Pitolisant Rizatriptan may decrease the excretion rate of Pitolisant which could result in a higher serum level.
Phenytoin Injection Phenytoin Injection The risk or severity of adverse effects can be increased when Phenytoin is combined with Rizatriptan.
Fosphenytoin Injection Fosphenytoin Injection The risk or severity of adverse effects can be increased when Rizatriptan is combined with Fosphenytoin.
Lumateperone Lumateperone The risk or severity of adverse effects can be increased when Rizatriptan is combined with Lumateperone.
Lasmiditan Lasmiditan The risk or severity of serotonin syndrome can be increased when Rizatriptan is combined with Lasmiditan.
Selpercatinib Selpercatinib The risk or severity of hypertension can be increased when Rizatriptan is combined with Selpercatinib.
Lemborexant Lemborexant The risk or severity of adverse effects can be increased when Rizatriptan is combined with Lemborexant.
Fenfluramine Fenfluramine The risk or severity of serotonin syndrome can be increased when Fenfluramine is combined with Rizatriptan.
Naxitamab-gqgk Injection Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Rizatriptan is combined with Naxitamab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives Drospirenone may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Viloxazine.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Fenoprofen Fenoprofen Fenoprofen may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Indomethacin Indomethacin Indomethacin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Mefenamic Acid Mefenamic Acid Mefenamic acid may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Naproxen Naproxen Naproxen may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Tolmetin Tolmetin Tolmetin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Sulindac Sulindac Sulindac may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Trazodone Trazodone The risk or severity of serotonin syndrome can be increased when Trazodone is combined with Rizatriptan.
Isotretinoin Isotretinoin Rizatriptan may decrease the excretion rate of Isotretinoin which could result in a higher serum level.
Sucralfate Sucralfate Sucralfate may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Floxuridine Floxuridine Floxuridine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Phenobarbital Phenobarbital The risk or severity of adverse effects can be increased when Rizatriptan is combined with Phenobarbital.
Metaxalone Metaxalone The risk or severity of adverse effects can be increased when Metaxalone is combined with Rizatriptan.
Methotrexate Injection Methotrexate Injection Methotrexate may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Levorphanol is combined with Rizatriptan.
Primidone Primidone The risk or severity of adverse effects can be increased when Primidone is combined with Rizatriptan.
Methsuximide Methsuximide The risk or severity of adverse effects can be increased when Rizatriptan is combined with Methsuximide.
Diethylpropion Diethylpropion The risk or severity of adverse effects can be increased when Diethylpropion is combined with Rizatriptan.
Chlorpromazine Chlorpromazine Chlorpromazine may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Diazepam Diazepam The risk or severity of adverse effects can be increased when Diazepam is combined with Rizatriptan.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Oxazepam is combined with Rizatriptan.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Flurazepam is combined with Rizatriptan.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Clorazepic acid is combined with Rizatriptan.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Rizatriptan.
Phenoxybenzamine Phenoxybenzamine The risk or severity of hypertension can be increased when Phenoxybenzamine is combined with Rizatriptan.
Carmustine Carmustine Carmustine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Amantadine Amantadine The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Rizatriptan.
Codeine Codeine The risk or severity of adverse effects can be increased when Codeine is combined with Rizatriptan.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Rizatriptan.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Rizatriptan.
Bromocriptine Bromocriptine Bromocriptine may increase the vasoconstricting activities of Rizatriptan.
Metaproterenol Metaproterenol The risk or severity of hypertension can be increased when Orciprenaline is combined with Rizatriptan.
Tranylcypromine Tranylcypromine The metabolism of Rizatriptan can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Rizatriptan can be decreased when combined with Phenelzine.
Procarbazine Procarbazine The metabolism of Rizatriptan can be decreased when combined with Procarbazine.
Ergoloid Mesylates Ergoloid Mesylates Ergoloid mesylate may increase the vasoconstricting activities of Rizatriptan.
Tetracycline Tetracycline Tetracycline may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Prochlorperazine Prochlorperazine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Prochlorperazine.
Thioridazine Thioridazine The risk or severity of adverse effects can be increased when Thioridazine is combined with Rizatriptan.
Trifluoperazine Trifluoperazine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Trifluoperazine.
Bleomycin Bleomycin Bleomycin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Sulfadiazine Sulfadiazine Sulfadiazine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Rizatriptan.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Rizatriptan.
Oxybutynin Oxybutynin Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin.
Benztropine Benztropine Benzatropine may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Maprotiline Maprotiline Maprotiline may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Ibuprofen Ibuprofen Ibuprofen may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Trihexyphenidyl Trihexyphenidyl Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine Orphenadrine Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Perphenazine.
Azathioprine Azathioprine Rizatriptan may decrease the excretion rate of Azathioprine which could result in a higher serum level.
Fluphenazine Fluphenazine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Fluphenazine.
Phentermine Phentermine The metabolism of Rizatriptan can be decreased when combined with Phentermine.
Methylphenidate Methylphenidate Methylphenidate may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Amoxapine Amoxapine The risk or severity of adverse effects can be increased when Amoxapine is combined with Rizatriptan.
Sulfasalazine Sulfasalazine Sulfasalazine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Phenazopyridine Phenazopyridine Phenazopyridine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Carbamazepine Carbamazepine Rizatriptan may decrease the excretion rate of Carbamazepine which could result in a higher serum level.
Molindone Molindone The risk or severity of adverse effects can be increased when Rizatriptan is combined with Molindone.
Methyldopa Methyldopa Rizatriptan may decrease the excretion rate of Methyldopa which could result in a higher serum level.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Rizatriptan.
Prazosin Prazosin Rizatriptan may decrease the antihypertensive activities of Prazosin.
Hydralazine Hydralazine Rizatriptan may decrease the excretion rate of Hydralazine which could result in a higher serum level.
Cimetidine Cimetidine Cimetidine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Warfarin Warfarin Rizatriptan may decrease the excretion rate of Warfarin which could result in a higher serum level.
Clonazepam Clonazepam The risk or severity of adverse effects can be increased when Rizatriptan is combined with Clonazepam.
Promethazine Promethazine Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Promethazine.
Meclofenamate Meclofenamate Meclofenamic acid may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Nitrofurantoin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Digoxin Digoxin Rizatriptan may decrease the excretion rate of Digoxin which could result in a higher serum level.
Loxapine Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Rizatriptan.
Chloroquine Chloroquine Chloroquine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Quinine Quinine The risk or severity of adverse effects can be increased when Quinine is combined with Rizatriptan.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Ethosuximide is combined with Rizatriptan.
Triamterene Triamterene Triamterene may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Chlorothiazide Chlorothiazide Chlorothiazide may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Chlorthalidone Chlorthalidone Chlorthalidone may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Metolazone Metolazone Metolazone may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Isosorbide Isosorbide Isosorbide may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Secobarbital Secobarbital The risk or severity of adverse effects can be increased when Secobarbital is combined with Rizatriptan.
Desipramine Desipramine Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Desipramine.
Amitriptyline Amitriptyline Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Amitriptyline.
Imipramine Imipramine Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Imipramine.
Probenecid Probenecid Rizatriptan may decrease the excretion rate of Probenecid which could result in a higher serum level.
Quinidine Quinidine Rizatriptan may decrease the excretion rate of Quinidine which could result in a higher serum level.
Procainamide Procainamide Rizatriptan may decrease the excretion rate of Procainamide which could result in a higher serum level.
Isoniazid Isoniazid The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Rizatriptan.
Pyrazinamide Pyrazinamide Pyrazinamide may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Disopyramide Disopyramide Disopyramide may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Valproic Acid Valproic Acid The risk or severity of adverse effects can be increased when Valproic acid is combined with Rizatriptan.
Butabarbital Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Rizatriptan.
Liothyronine Liothyronine Liothyronine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Methimazole Methimazole Methimazole may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Chlorpropamide Chlorpropamide Chlorpropamide may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Tolbutamide Tolbutamide Rizatriptan may decrease the excretion rate of Tolbutamide which could result in a higher serum level.
Tolazamide Tolazamide Tolazamide may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Dextromethorphan Dextromethorphan The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Rizatriptan.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Cyclobenzaprine is combined with Rizatriptan.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Rizatriptan.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Cyproheptadine Cyproheptadine The risk or severity of adverse effects can be increased when Cyproheptadine is combined with Rizatriptan.
Clemastine Clemastine The risk or severity of adverse effects can be increased when Clemastine is combined with Rizatriptan.
Chlorpheniramine Chlorpheniramine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Rizatriptan.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Meclizine is combined with Rizatriptan.
Ethambutol Ethambutol Ethambutol may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Methyclothiazide Methyclothiazide Methyclothiazide may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Hydrochlorothiazide Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Rizatriptan is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone The risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Rizatriptan.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Rizatriptan.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Methocarbamol is combined with Rizatriptan.
Pyridoxine Pyridoxine Pyridoxine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Folic Acid Folic Acid Folic acid may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The metabolism of Rizatriptan can be decreased when combined with Propranolol.
Minoxidil Minoxidil Rizatriptan may decrease the antihypertensive activities of Minoxidil.
Pseudoephedrine Pseudoephedrine The metabolism of Rizatriptan can be decreased when combined with Pseudoephedrine.
Nortriptyline Nortriptyline The risk or severity of adverse effects can be increased when Nortriptyline is combined with Rizatriptan.
Spironolactone Spironolactone Spironolactone may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection Amphotericin B Injection Amphotericin B may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Phytonadione Phytonadione Rizatriptan may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Nadolol Nadolol Rizatriptan may decrease the excretion rate of Nadolol which could result in a higher serum level.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Rizatriptan.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Nalbuphine is combined with Rizatriptan.
Allopurinol Allopurinol Allopurinol may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Rizatriptan.
Flavoxate Flavoxate Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Colchicine Colchicine Rizatriptan may decrease the excretion rate of Colchicine which could result in a higher serum level.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Cefadroxil Cefadroxil Cefadroxil may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Cephalexin Cephalexin Cephalexin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Dacarbazine Dacarbazine Dacarbazine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Acetazolamide is combined with Rizatriptan.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Rizatriptan is combined with Pyrantel.
Captopril Captopril Rizatriptan may decrease the antihypertensive activities of Captopril.
Isoxsuprine Isoxsuprine The risk or severity of hypertension can be increased when Rizatriptan is combined with Isoxsuprine.
Ethacrynic Acid Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Metoprolol Metoprolol Metoprolol may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Hydroxyzine Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Rizatriptan is combined with Thiothixene.
Aspirin Aspirin Acetylsalicylic acid may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Salsalate Salsalate Salsalate may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Rizatriptan.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Rizatriptan.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Triazolam is combined with Rizatriptan.
Dicyclomine Dicyclomine Dicyclomine may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Hyoscyamine Hyoscyamine Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline Propantheline Propantheline may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Trimethoprim Trimethoprim Trimethoprim may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Diltiazem Diltiazem Rizatriptan may decrease the antihypertensive activities of Diltiazem.
Nifedipine Nifedipine Rizatriptan may decrease the excretion rate of Nifedipine which could result in a higher serum level.
Timolol Timolol Timolol may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Verapamil Verapamil Verapamil may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Atenolol Atenolol Rizatriptan may decrease the antihypertensive activities of Atenolol.
Pindolol Pindolol The risk or severity of adverse effects can be increased when Rizatriptan is combined with Pindolol.
Cisplatin Injection Cisplatin Injection Rizatriptan may decrease the excretion rate of Cisplatin which could result in a higher serum level.
Diflunisal Diflunisal Diflunisal may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Piroxicam Piroxicam Piroxicam may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Bumetanide Bumetanide Bumetanide may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Glipizide Glipizide Rizatriptan may decrease the excretion rate of Glipizide which could result in a higher serum level.
Indapamide Indapamide Indapamide may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy.
Amoxicillin Amoxicillin Rizatriptan may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Oxacillin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Pentoxifylline Pentoxifylline Pentoxifylline may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Pentamidine Injection Pentamidine Injection Pentamidine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Ceftriaxone Injection Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Labetalol Labetalol Labetalol may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Auranofin Auranofin Rizatriptan may decrease the excretion rate of Auranofin which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection Leuprolide may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Gemfibrozil Gemfibrozil Rizatriptan may decrease the excretion rate of Gemfibrozil which could result in a higher serum level.
Guanabenz Guanabenz The risk or severity of hypertension can be increased when Guanabenz is combined with Rizatriptan.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Ketoprofen Ketoprofen Ketoprofen may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Cefotetan Injection Cefotetan Injection Cefotetan may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Pimozide Pimozide The risk or severity of adverse effects can be increased when Rizatriptan is combined with Pimozide.
Enalapril Enalapril Rizatriptan may decrease the antihypertensive activities of Enalapril.
Flurbiprofen Flurbiprofen Flurbiprofen may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Aztreonam Injection Aztreonam Injection Aztreonam may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Buspirone Buspirone The risk or severity of serotonin syndrome can be increased when Buspirone is combined with Rizatriptan.
Ciprofloxacin Ciprofloxacin Ciprofloxacin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Mesalamine Mesalamine Mesalazine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Diclofenac Diclofenac Diclofenac may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Fluoxetine Fluoxetine The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Rizatriptan.
Nimodipine Nimodipine Rizatriptan may decrease the antihypertensive activities of Nimodipine.
Clozapine Clozapine Clozapine may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Rizatriptan is combined with Estazolam.
Didanosine Didanosine Didanosine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Pentostatin Injection Pentostatin Injection Pentostatin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Benazepril Benazepril Rizatriptan may decrease the antihypertensive activities of Benazepril.
Etodolac Etodolac Etodolac may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Felodipine Felodipine Rizatriptan may decrease the antihypertensive activities of Felodipine.
Fosinopril Fosinopril Fosinopril may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Nabumetone Nabumetone Nabumetone may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Quinapril Quinapril Rizatriptan may decrease the antihypertensive activities of Quinapril.
Ramipril Ramipril Rizatriptan may decrease the antihypertensive activities of Ramipril.
Amlodipine Amlodipine Rizatriptan may decrease the antihypertensive activities of Amlodipine.
Lisinopril Lisinopril Lisinopril may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Oxaprozin Oxaprozin Oxaprozin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Bisoprolol Bisoprolol Bisoprolol may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Zolpidem Zolpidem Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin Doxazosin Rizatriptan may decrease the antihypertensive activities of Doxazosin.
Terazosin Terazosin Rizatriptan may decrease the antihypertensive activities of Terazosin.
Isradipine Isradipine Isradipine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Cisapride Cisapride The risk or severity of adverse effects can be increased when Cisapride is combined with Rizatriptan.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Rizatriptan is combined with Gabapentin.
Venlafaxine Venlafaxine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Rizatriptan.
Fluvoxamine Fluvoxamine The risk or severity of adverse effects can be increased when Fluvoxamine is combined with Rizatriptan.
Nefazodone Nefazodone The risk or severity of adverse effects can be increased when Rizatriptan is combined with Nefazodone.
Lamotrigine Lamotrigine Lamotrigine may increase the central nervous system depressant (CNS depressant) activities of Rizatriptan.
Losartan Losartan Rizatriptan may decrease the antihypertensive activities of Losartan.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Tramadol Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Rizatriptan.
Carboplatin Injection Carboplatin Injection Carboplatin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Moexipril Moexipril Rizatriptan may decrease the antihypertensive activities of Moexipril.
Ifosfamide Injection Ifosfamide Injection Rizatriptan may decrease the excretion rate of Ifosfamide which could result in a higher serum level.
Nicardipine Nicardipine Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Nicardipine.
Bupropion Bupropion The risk or severity of adverse effects can be increased when Rizatriptan is combined with Bupropion.
Ticlopidine Ticlopidine Ticlopidine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Metformin Metformin Metformin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Nisoldipine Nisoldipine Nisoldipine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Lamivudine Lamivudine Lamivudine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Riluzole Riluzole The risk or severity of adverse effects can be increased when Riluzole is combined with Rizatriptan.
Acarbose Acarbose Acarbose may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Gemcitabine Injection Gemcitabine Injection Gemcitabine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Meropenem Injection Meropenem Injection Meropenem may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Clomipramine Clomipramine The risk or severity of adverse effects can be increased when Rizatriptan is combined with Clomipramine.
Fosfomycin Fosfomycin Fosfomycin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Mirtazapine Mirtazapine Rizatriptan may increase the serotonergic activities of Mirtazapine.
Trandolapril Trandolapril Rizatriptan may decrease the antihypertensive activities of Trandolapril.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Rizatriptan.
Valsartan Valsartan Rizatriptan may decrease the antihypertensive activities of Valsartan.
Pramipexole Pramipexole Rizatriptan may increase the sedative activities of Pramipexole.
Donepezil Donepezil The risk or severity of adverse effects can be increased when Donepezil is combined with Rizatriptan.
Carvedilol Carvedilol Rizatriptan may decrease the antihypertensive activities of Carvedilol.
Nilutamide Nilutamide Nilutamide may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Flutamide Flutamide Flutamide may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Selegiline Selegiline The metabolism of Rizatriptan can be decreased when combined with Selegiline.
Sertraline Sertraline The risk or severity of adverse effects can be increased when Rizatriptan is combined with Sertraline.
Propafenone Propafenone The risk or severity of hypertension can be increased when Rizatriptan is combined with Propafenone.
Irbesartan Irbesartan Rizatriptan may decrease the antihypertensive activities of Irbesartan.
Tamsulosin Tamsulosin Tamsulosin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Ropinirole Ropinirole Rizatriptan may increase the sedative activities of Ropinirole.
Finasteride Finasteride The risk or severity of hypertension can be increased when Rizatriptan is combined with Finasteride.
Quetiapine Quetiapine Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Quetiapine.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Rizatriptan.
Paroxetine Paroxetine The risk or severity of serotonin syndrome can be increased when Paroxetine is combined with Rizatriptan.
Tolcapone Tolcapone The risk or severity of adverse effects can be increased when Tolcapone is combined with Rizatriptan.
Citalopram Citalopram The risk or severity of adverse effects can be increased when Citalopram is combined with Rizatriptan.
Capecitabine Capecitabine Rizatriptan may decrease the excretion rate of Capecitabine which could result in a higher serum level.
Efavirenz Efavirenz The risk or severity of adverse effects can be increased when Efavirenz is combined with Rizatriptan.
Abacavir Abacavir Rizatriptan may decrease the excretion rate of Abacavir which could result in a higher serum level.
Celecoxib Celecoxib Celecoxib may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Rosiglitazone Rosiglitazone Rosiglitazone may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Tolterodine Tolterodine Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
Thalidomide Thalidomide Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Oseltamivir Oseltamivir Oseltamivir may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Balsalazide Balsalazide Balsalazide may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Nateglinide Nateglinide Nateglinide may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Rizatriptan is combined with Levetiracetam.
Rabeprazole Rabeprazole Rizatriptan may decrease the excretion rate of Rabeprazole which could result in a higher serum level.

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