Sulfasalazine

Generic name: Pronounced as (sul fa sal' a zeen)
Brand names
  • Azulfidine®
  • Azulfidine® EN-tabs®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 01/15/2022

Sulfasalazine is used to treat ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum) and also to maintain improvement of ulcerative colitis symptoms. Sulfasalazine delayed-release (Azulfidine EN-tabs) is also used to treat rheumatoid arthritis in adults whose disease has not responded well to other medications or could not be tolerated. Sulfasalazine delayed-release (Azulfidine EN-tabs) is also used to treat polyarticular juvenile idiopathic arthritis (PJIA; a type of childhood arthritis that affects five or more joints during the first six months of the condition, causing pain, swelling, and loss of function) in children who have not been helped by other medications. Sulfasalazine is in a class of medications called anti-inflammatory drugs. It works by reducing inflammation (swelling) inside the body.

Sulfasalazine comes as regular and delayed-release (releases the medication in the intestine to prevent irritation to the stomach and to allow the medication to work in the intestine where its effects are needed) tablets. It usually is taken 3 to 6 times a day in evenly spaced doses throughout the day so that no more than 8 hours separates any two doses, if possible. For treatment of rheumatoid arthritis or polyarticular juvenile idiopathic arthritis, sulfasalazine delayed-release tablets are usually taken twice a day in evenly spaced doses throughout the day. Take sulfasalazine after a meal or with a light snack, then drink a full glass of water. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sulfasalazine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow delayed-release tablets whole; do not crush or chew them.

Drink plenty of fluids while taking sulfasalazine.

Continue to take sulfasalazine even if you feel well. Do not stop taking sulfasalazine without talking to your doctor.

Sulfasalazine is also used to treat bowel inflammation, diarrhea (stool frequency), rectal bleeding, and abdominal pain in Crohn's disease. Talk to your doctor about the possible risks of using this drug for your condition.

Before taking sulfasalazine,

  • tell your doctor if you are allergic to sulfasalazine; sulfapyridine; salicylate pain relievers such as aspirin, choline magnesium trisalicylate, diflunisal, magnesium salicylate (Doan's, others); balsalazide (Colazal); mesalamine (Asacol, Pentasa, Rowasa, others); olsalazine (Dipentum); sulfa drugs; any other medications; or the ingredients in sulfasalzine tablets or delayed-release tablets. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: digoxin (Lanoxin), folic acid, and methotrexate (Trexall, Xatmep).

  • tell your doctor if you have or have ever had an intestinal obstruction (a blockage in your intestine), a urinary obstruction (a blockage of urine flowing out of the bladder), or porphyria (condition in which abnormal substances build up in the blood and cause problems with the skin or nervous system). Your doctor will probably tell you not to take sulfasalazine.

  • tell your doctor if you have an infection or if you have or have ever had an infection that keeps coming back. Also tell your doctor if you have or have ever had asthma, glucose-6-phosphate dehydrogenase (G-6-PD) deficiency (an inherited blood disease), kidney stones, blood problems, or kidney or liver disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking sulfasalazine, call your doctor.

  • you should know that this medication may decrease fertility in men. Fertility usually returns when the medicine is stopped. Talk to your doctor about the risks of taking sulfasalazine.

  • plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Sulfasalazine may make your skin sensitive to sunlight.

Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Sulfasalazine may cause side effects.

  • Tell your doctor if any of these symptoms are severe or do not go away:

    • yellow or orange discoloration of urine or skin

    • diarrhea

    • headache

    • loss of appetite

    • upset stomach

    • vomiting

    • stomach pain

  • If you have any of the following symptoms, stop taking sulfasalazine and call your doctor immediately:

    • rash, hives, itching or peeling or blistering skin

    • swelling of the eyes, face, lips, tongue, mouth, or throat

    • difficulty breathing or swallowing

    • swollen glands

    • fever, sore throat, chills, cough, night sweats, and other signs of infection

    • pale skin, tiredness, or shortness of breath

    • joint or muscle aches

    • yellowing of the skin or eyes

    • pain in the right upper part of the stomach

    • difficult or painful urination or cloudy, discolored or blood urine

    • chest pain

    • new or worsening cough

    • tiredness

    • unusual bleeding or bruising

    • weakness

    • seizures

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

  • nausea

  • vomiting

  • stomach pain

  • tiredness

  • seizures

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to sulfasalazine.

Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin Sulfasalazine may increase the neuroexcitatory activities of Moxifloxacin.
Repaglinide Repaglinide Sulfasalazine may increase the hypoglycemic activities of Repaglinide.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection Sulfasalazine may increase the hypoglycemic activities of Insulin glargine.
Leflunomide Leflunomide The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Leflunomide.
Atorvastatin Atorvastatin The excretion of Atorvastatin can be decreased when combined with Sulfasalazine.
Alendronate Alendronate The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Alendronic acid.
Anagrelide Anagrelide The risk or severity of bleeding can be increased when Anagrelide is combined with Sulfasalazine.
Candesartan Candesartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Candesartan is combined with Sulfasalazine.
Cilostazol Cilostazol The risk or severity of bleeding can be increased when Sulfasalazine is combined with Cilostazol.
Clopidogrel Clopidogrel The risk or severity of bleeding can be increased when Sulfasalazine is combined with Clopidogrel.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The excretion of Erythromycin can be decreased when combined with Sulfasalazine.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Sulfasalazine may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate Fenofibrate Sulfasalazine may decrease the excretion rate of Fenofibrate which could result in a higher serum level.
Guanfacine Guanfacine The therapeutic efficacy of Guanfacine can be decreased when used in combination with Sulfasalazine.
Magnesium Hydroxide Magnesium Hydroxide Sulfasalazine may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Methylergonovine Methylergonovine The risk or severity of hypertension can be increased when Methylergometrine is combined with Sulfasalazine.
Miglitol Miglitol Sulfasalazine may increase the hypoglycemic activities of Miglitol.
Mycophenolate Mycophenolate The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Mycophenolic acid.
Naratriptan Naratriptan The risk or severity of hypertension can be increased when Sulfasalazine is combined with Naratriptan.
Olsalazine Olsalazine The therapeutic efficacy of Olsalazine can be decreased when used in combination with Sulfasalazine.
Penbutolol Penbutolol Sulfasalazine may decrease the antihypertensive activities of Acebutolol.
Potassium Potassium Sulfasalazine may decrease the excretion rate of Potassium cation which could result in a higher serum level.
Prednisone Prednisone The risk or severity of gastrointestinal irritation can be increased when Prednisone is combined with Sulfasalazine.
Ranitidine Ranitidine Sulfasalazine may decrease the excretion rate of Ranitidine which could result in a higher serum level.
Reserpine Reserpine The therapeutic efficacy of Reserpine can be decreased when used in combination with Sulfasalazine.
Rizatriptan Rizatriptan Sulfasalazine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Sumatriptan Sumatriptan Sulfasalazine may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus The risk or severity of renal failure can be increased when Sulfasalazine is combined with Tacrolimus.
Tiludronate Tiludronate The risk or severity of gastrointestinal bleeding can be increased when Sulfasalazine is combined with Etidronic acid.
Triamcinolone Triamcinolone The risk or severity of gastrointestinal irritation can be increased when Triamcinolone is combined with Sulfasalazine.
Zolmitriptan Zolmitriptan The risk or severity of hypertension can be increased when Zolmitriptan is combined with Sulfasalazine.
Ampicillin Injection Ampicillin Injection Sulfasalazine may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection Sulfasalazine may decrease the excretion rate of Doxycycline which could result in a higher serum level.
Fluconazole Injection Fluconazole Injection Sulfasalazine may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Foscarnet Injection Foscarnet Injection The risk or severity of nephrotoxicity can be increased when Sulfasalazine is combined with Foscarnet.
Hydromorphone Injection Hydromorphone Injection Sulfasalazine may decrease the excretion rate of Hydromorphone which could result in a higher serum level.
Interferon Beta-1b Injection Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Sulfasalazine.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Sulfasalazine.
Levofloxacin Injection Levofloxacin Injection Sulfasalazine may decrease the excretion rate of Levofloxacin which could result in a higher serum level.
Meperidine Injection Meperidine Injection Sulfasalazine may decrease the excretion rate of Meperidine which could result in a higher serum level.
Methylprednisolone Injection Methylprednisolone Injection The risk or severity of gastrointestinal irritation can be increased when Sulfasalazine is combined with Methylprednisolone.
Metoclopramide Injection Metoclopramide Injection The risk or severity of methemoglobinemia can be increased when Sulfasalazine is combined with Metoclopramide.
Pamidronate Injection Pamidronate Injection The risk or severity of gastrointestinal bleeding can be increased when Sulfasalazine is combined with Pamidronic acid.
Vancomycin Injection Vancomycin Injection Sulfasalazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Zidovudine Injection Zidovudine Injection The risk or severity of bleeding can be increased when Zidovudine is combined with Sulfasalazine.
Altretamine Altretamine Sulfasalazine may decrease the excretion rate of Amphetamine which could result in a higher serum level.
Cefuroxime Cefuroxime The risk or severity of nephrotoxicity can be increased when Sulfasalazine is combined with Cefuroxime.
Cyclosporine Cyclosporine Sulfasalazine may increase the immunosuppressive activities of Cyclosporine.
Enoxaparin Injection Enoxaparin Injection The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Enoxaparin.
Torsemide Torsemide The therapeutic efficacy of Torasemide can be decreased when used in combination with Sulfasalazine.
Eprosartan Eprosartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Eprosartan is combined with Sulfasalazine.
Hydroxychloroquine Hydroxychloroquine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Hydroxychloroquine.
Meloxicam Meloxicam The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Meloxicam.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Risedronate Risedronate The risk or severity of gastrointestinal bleeding can be increased when Sulfasalazine is combined with Risedronic acid.
Sevelamer Sevelamer Sevelamer can cause a decrease in the absorption of Sulfasalazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Telmisartan Telmisartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Telmisartan is combined with Sulfasalazine.
Temozolomide Temozolomide The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Temozolomide.
Zaleplon Zaleplon Sulfasalazine may decrease the excretion rate of Zaleplon which could result in a higher serum level.
Anakinra Anakinra The risk or severity of adverse effects can be increased when Anakinra is combined with Sulfasalazine.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Sulfasalazine.
Pentosan Polysulfate Pentosan Polysulfate The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Pentosan polysulfate.
Trimipramine Trimipramine The risk or severity of hypertension can be increased when Trimipramine is combined with Sulfasalazine.
Etanercept Injection Etanercept Injection The risk or severity of neutropenia can be increased when Etanercept is combined with Sulfasalazine.
Perindopril Perindopril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Perindopril.
Tenofovir Tenofovir Sulfasalazine may increase the nephrotoxic activities of Tenofovir.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Choline magnesium trisalicylate.
Sirolimus Sirolimus The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Sirolimus.
Dutasteride Dutasteride The risk or severity of hypertension can be increased when Sulfasalazine is combined with Dutasteride.
Epinephrine Injection Epinephrine Injection The risk or severity of hypertension can be increased when Epinephrine is combined with Sulfasalazine.
Epirubicin Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with Sulfasalazine.
Eplerenone Eplerenone The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Eplerenone.
Escitalopram Escitalopram The risk or severity of gastrointestinal bleeding can be increased when Escitalopram is combined with Sulfasalazine.
Olmesartan Olmesartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Olmesartan is combined with Sulfasalazine.
Zonisamide Zonisamide The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Zonisamide.
Adalimumab Injection Adalimumab Injection The risk or severity of adverse effects can be increased when Adalimumab is combined with Sulfasalazine.
Aripiprazole Aripiprazole The risk or severity of hypertension can be increased when Sulfasalazine is combined with Aripiprazole.
Atomoxetine Atomoxetine Sulfasalazine may decrease the excretion rate of Atomoxetine which could result in a higher serum level.
Dexmethylphenidate Dexmethylphenidate The risk or severity of hypertension can be increased when Sulfasalazine is combined with Dexmethylphenidate.
Ezetimibe Ezetimibe Sulfasalazine may decrease the excretion rate of Ezetimibe which could result in a higher serum level.
Glatiramer Injection Glatiramer Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Glatiramer.
Atazanavir Atazanavir The risk or severity of nephrotoxicity can be increased when Sulfasalazine is combined with Atazanavir.
Almotriptan Almotriptan Sulfasalazine may decrease the excretion rate of Almotriptan which could result in a higher serum level.
Eletriptan Eletriptan The risk or severity of hypertension can be increased when Eletriptan is combined with Sulfasalazine.
Rosuvastatin Rosuvastatin Sulfasalazine may decrease the excretion rate of Rosuvastatin which could result in a higher serum level.
Emtricitabine Emtricitabine Sulfasalazine may decrease the excretion rate of Emtricitabine which could result in a higher serum level.
Memantine Memantine Sulfasalazine may decrease the excretion rate of Memantine which could result in a higher serum level.
Tegaserod Tegaserod Sulfasalazine may decrease the excretion rate of Tegaserod which could result in a higher serum level.
Tadalafil Tadalafil Sulfasalazine may decrease the excretion rate of Tadalafil which could result in a higher serum level.
Frovatriptan Frovatriptan The risk or severity of hypertension can be increased when Sulfasalazine is combined with Frovatriptan.
Gemifloxacin Gemifloxacin Sulfasalazine may increase the neuroexcitatory activities of Gemifloxacin.
Progesterone Progesterone Progesterone may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Infliximab Injection Infliximab Injection The risk or severity of adverse effects can be increased when Infliximab is combined with Sulfasalazine.
Protriptyline Protriptyline The risk or severity of hypertension can be increased when Protriptyline is combined with Sulfasalazine.
Duloxetine Duloxetine The risk or severity of gastrointestinal bleeding can be increased when Duloxetine is combined with Sulfasalazine.
Tinidazole Tinidazole Sulfasalazine may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Bosentan Bosentan The therapeutic efficacy of Bosentan can be decreased when used in combination with Sulfasalazine.
Cefditoren Cefditoren Sulfasalazine may decrease the excretion rate of Cefdinir which could result in a higher serum level.
Natalizumab Injection Natalizumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Natalizumab.
Cyanocobalamin Injection Cyanocobalamin Injection Sulfasalazine may decrease the excretion rate of Hydroxocobalamin which could result in a higher serum level.
Erlotinib Erlotinib Erlotinib may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Eszopiclone Eszopiclone Sulfasalazine may decrease the excretion rate of Eszopiclone which could result in a higher serum level.
Ganciclovir Ganciclovir Sulfasalazine may decrease the excretion rate of Ganciclovir which could result in a higher serum level.
Insulin Aspart (rDNA Origin) Injection Insulin Aspart (rDNA Origin) Injection Sulfasalazine may increase the hypoglycemic activities of Insulin aspart.
Ribavirin Ribavirin Sulfasalazine may decrease the excretion rate of Ribavirin which could result in a higher serum level.
Solifenacin Solifenacin The risk or severity of hypertension can be increased when Sulfasalazine is combined with Solifenacin.
Valganciclovir Valganciclovir Sulfasalazine may decrease the excretion rate of Valganciclovir which could result in a higher serum level.
Zoledronic Acid Injection Zoledronic Acid Injection The risk or severity of gastrointestinal bleeding can be increased when Sulfasalazine is combined with Zoledronic acid.
Adefovir Adefovir The risk or severity of nephrotoxicity can be increased when Sulfasalazine is combined with Adefovir.
Dextroamphetamine Dextroamphetamine Sulfasalazine may decrease the excretion rate of Amphetamine which could result in a higher serum level.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Sulfasalazine.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Sulfasalazine.
Pramlintide Injection Pramlintide Injection Sulfasalazine may increase the hypoglycemic activities of Pramlintide.
Exenatide Injection Exenatide Injection Sulfasalazine may increase the hypoglycemic activities of Exenatide.
Ibandronate Ibandronate The risk or severity of gastrointestinal bleeding can be increased when Sulfasalazine is combined with Ibandronate.
Isocarboxazid Isocarboxazid The risk or severity of hypertension can be increased when Sulfasalazine is combined with Isocarboxazid.
Ramelteon Ramelteon Sulfasalazine may decrease the excretion rate of Ramelteon which could result in a higher serum level.
Fentanyl Fentanyl Sulfasalazine may decrease the excretion rate of Fentanyl which could result in a higher serum level.
Pregabalin Pregabalin Sulfasalazine may decrease the excretion rate of Pregabalin which could result in a higher serum level.
Deferasirox Deferasirox The risk or severity of gastrointestinal bleeding and peptic ulcer can be increased when Sulfasalazine is combined with Deferasirox.
Phenylephrine Phenylephrine The risk or severity of hypertension can be increased when Phenylephrine is combined with Sulfasalazine.
Insulin Detemir (rDNA Origin) Injection Insulin Detemir (rDNA Origin) Injection Sulfasalazine may increase the hypoglycemic activities of Insulin detemir.
Ranolazine Ranolazine Sulfasalazine may decrease the excretion rate of Ranolazine which could result in a higher serum level.
Abatacept Injection Abatacept Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Abatacept.
Rasagiline Rasagiline Sulfasalazine may decrease the excretion rate of Rasagiline which could result in a higher serum level.
Imatinib Imatinib The risk or severity of adverse effects can be increased when Imatinib is combined with Sulfasalazine.
Sitagliptin Sitagliptin Sulfasalazine may increase the hypoglycemic activities of Sitagliptin.
Varenicline Varenicline Sulfasalazine may decrease the excretion rate of Varenicline which could result in a higher serum level.
Bevacizumab Injection Bevacizumab Injection The risk or severity of adverse effects can be increased when Bevacizumab is combined with Sulfasalazine.
Gefitinib Gefitinib Gefitinib may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Albuterol Albuterol Sulfasalazine may decrease the excretion rate of Salbutamol which could result in a higher serum level.
Paliperidone Paliperidone Sulfasalazine may decrease the excretion rate of Paliperidone which could result in a higher serum level.
Bortezomib Bortezomib The risk or severity of adverse effects can be increased when Bortezomib is combined with Sulfasalazine.
Clofarabine Injection Clofarabine Injection The risk or severity of adverse effects can be increased when Clofarabine is combined with Sulfasalazine.
Hepatitis B Vaccine Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Sulfasalazine.
Influenza Vaccine, Inactivated or Recombinant Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Sulfasalazine.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Sulfasalazine.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Sulfasalazine.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection Sulfasalazine may increase the hypoglycemic activities of Insulin glulisine.
Lubiprostone Lubiprostone Sulfasalazine may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Sulfasalazine.
Primaquine Primaquine The risk or severity of methemoglobinemia can be increased when Sulfasalazine is combined with Primaquine.
Rituximab Injection Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Sulfasalazine.
Aliskiren Aliskiren The risk or severity of renal failure and hypertension can be increased when Sulfasalazine is combined with Aliskiren.
Bismuth Subsalicylate Bismuth Subsalicylate The therapeutic efficacy of Bismuth subsalicylate can be decreased when used in combination with Sulfasalazine.
Pemetrexed Injection Pemetrexed Injection Sulfasalazine may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Lisdexamfetamine Lisdexamfetamine The risk or severity of hypertension can be increased when Sulfasalazine is combined with Lisdexamfetamine.
Vorinostat Vorinostat The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Vorinostat.
Sorafenib Sorafenib The risk or severity of adverse effects can be increased when Sorafenib is combined with Sulfasalazine.
Sunitinib Sunitinib The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Sunitinib.
Dronabinol Dronabinol Dronabinol may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Levocetirizine Levocetirizine Sulfasalazine may decrease the excretion rate of Levocetirizine which could result in a higher serum level.
Pegaptanib Injection Pegaptanib Injection Sulfasalazine may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Dasatinib Dasatinib The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Dasatinib.
Azacitidine Injection Azacitidine Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Azacitidine.
Ivermectin Ivermectin Sulfasalazine may decrease the excretion rate of Ivermectin which could result in a higher serum level.
Temsirolimus Temsirolimus The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Temsirolimus.
Antipyrine-Benzocaine Otic Antipyrine-Benzocaine Otic The risk or severity of methemoglobinemia can be increased when Sulfasalazine is combined with Benzocaine.
Nelarabine Injection Nelarabine Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Nelarabine.
Lenalidomide Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with Sulfasalazine.
Nilotinib Nilotinib The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Nilotinib.
Bexarotene Bexarotene The risk or severity of adverse effects can be increased when Bexarotene is combined with Sulfasalazine.
Budesonide Budesonide The risk or severity of gastrointestinal irritation can be increased when Sulfasalazine is combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The risk or severity of adverse effects can be increased when Chloramphenicol is combined with Sulfasalazine.
Decitabine Injection Decitabine Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Decitabine.
Desmopressin Desmopressin The risk or severity of hypertension, hyponatremia, and water intoxication can be increased when Sulfasalazine is combined with Desmopressin.
Doripenem Injection Doripenem Injection Sulfasalazine may decrease the excretion rate of Doripenem which could result in a higher serum level.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Arsenic trioxide.
Mitoxantrone Injection Mitoxantrone Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Mitoxantrone.
Desvenlafaxine Desvenlafaxine The risk or severity of gastrointestinal bleeding can be increased when Desvenlafaxine is combined with Sulfasalazine.
Cevimeline Cevimeline Sulfasalazine may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Nebivolol Nebivolol Sulfasalazine may decrease the antihypertensive activities of Nebivolol.
Tretinoin Tretinoin The risk or severity of adverse effects can be increased when Tretinoin is combined with Sulfasalazine.
Bendamustine Injection Bendamustine Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Bendamustine.
Leucovorin Injection Leucovorin Injection The serum concentration of Leucovorin can be decreased when it is combined with Sulfasalazine.
Certolizumab Injection Certolizumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Ixabepilone.
Irinotecan Injection Irinotecan Injection The risk or severity of adverse effects can be increased when Irinotecan is combined with Sulfasalazine.
Levoleucovorin Injection Levoleucovorin Injection The serum concentration of Levoleucovorin can be decreased when it is combined with Sulfasalazine.
Daptomycin Injection Daptomycin Injection Sulfasalazine may decrease the excretion rate of Daptomycin which could result in a higher serum level.
Estramustine Estramustine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Estramustine.
Methylnaltrexone Injection Methylnaltrexone Injection Sulfasalazine may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Sulfasalazine.
Midazolam Midazolam Sulfasalazine may decrease the excretion rate of Midazolam which could result in a higher serum level.
Dexrazoxane Injection Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Sulfasalazine.
Eltrombopag Eltrombopag Eltrombopag may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Ibritumomab Injection Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Sulfasalazine.
Milnacipran Milnacipran The risk or severity of gastrointestinal bleeding can be increased when Milnacipran is combined with Sulfasalazine.
Plerixafor Injection Plerixafor Injection Sulfasalazine may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Sodium Phosphate Sodium Phosphate The risk or severity of renal failure can be increased when Sodium phosphate, monobasic is combined with Sulfasalazine.
Fesoterodine Fesoterodine Sulfasalazine may decrease the excretion rate of Fesoterodine which could result in a higher serum level.
Betaxolol Betaxolol Sulfasalazine may decrease the antihypertensive activities of Betaxolol.
Iloperidone Iloperidone The risk or severity of hypertension can be increased when Sulfasalazine is combined with Iloperidone.
Prasugrel Prasugrel The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Prasugrel.
Everolimus Everolimus The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Everolimus.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The risk or severity of hyperkalemia can be increased when Sulfasalazine is combined with Tolvaptan.
Dronedarone Dronedarone The risk or severity of hypertension can be increased when Sulfasalazine is combined with Dronedarone.
Pralatrexate Injection Pralatrexate Injection The serum concentration of Pralatrexate can be increased when it is combined with Sulfasalazine.
Palonosetron Injection Palonosetron Injection Sulfasalazine may decrease the excretion rate of Palonosetron which could result in a higher serum level.
Saxagliptin Saxagliptin Sulfasalazine may increase the hypoglycemic activities of Saxagliptin.
Telavancin Injection Telavancin Injection Sulfasalazine may decrease the excretion rate of Telavancin which could result in a higher serum level.
Romidepsin Injection Romidepsin Injection The excretion of Romidepsin can be decreased when combined with Sulfasalazine.
Topotecan Topotecan The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Topotecan.
Golimumab Injection Golimumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Golimumab.
Pazopanib Pazopanib The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Pazopanib.
Asenapine Asenapine The risk or severity of hypertension can be increased when Sulfasalazine is combined with Asenapine.
Pitavastatin Pitavastatin Sulfasalazine may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Denosumab Injection Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Sulfasalazine.
Dabigatran Dabigatran The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Dabigatran.
Liraglutide Injection Liraglutide Injection Sulfasalazine may increase the hypoglycemic activities of Liraglutide.
Tocilizumab Injection Tocilizumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Tocilizumab.
Dalfampridine Dalfampridine Sulfasalazine may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
Fingolimod Fingolimod Sulfasalazine may increase the immunosuppressive activities of Fingolimod.
Eribulin Injection Eribulin Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Eribulin.
Cabazitaxel Injection Cabazitaxel Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Cabazitaxel.
Ceftaroline Injection Ceftaroline Injection The risk or severity of nephrotoxicity can be increased when Sulfasalazine is combined with Ceftaroline fosamil.
Lurasidone Lurasidone The risk or severity of hypertension can be increased when Sulfasalazine is combined with Lurasidone.
Acetaminophen Injection Acetaminophen Injection The risk or severity of adverse effects can be increased when Acetaminophen is combined with Sulfasalazine.
Vilazodone Vilazodone The risk or severity of hypertension can be increased when Sulfasalazine is combined with Vilazodone.
Ipilimumab Injection Ipilimumab Injection Sulfasalazine may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection The risk or severity of adverse effects can be increased when Aldesleukin is combined with Sulfasalazine.
Sipuleucel-T Injection Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Sulfasalazine.
Terbutaline Injection Terbutaline Injection Sulfasalazine may decrease the excretion rate of Terbutaline which could result in a higher serum level.
Belimumab Injection Belimumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Belimumab.
Azilsartan Azilsartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Azilsartan medoxomil is combined with Sulfasalazine.
Busulfan Injection Busulfan Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Busulfan.
Roflumilast Roflumilast Roflumilast may increase the immunosuppressive activities of Sulfasalazine.
Linagliptin Linagliptin Sulfasalazine may increase the hypoglycemic activities of Linagliptin.
Rilpivirine Rilpivirine Rilpivirine may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Telaprevir Telaprevir Sulfasalazine may decrease the excretion rate of Glecaprevir which could result in a higher serum level.
Potassium Iodide Potassium Iodide Potassium Iodide may increase the hyperkalemic activities of Sulfasalazine.
Cyclophosphamide Injection Cyclophosphamide Injection The risk or severity of adverse effects can be increased when Cyclophosphamide is combined with Sulfasalazine.
Rivaroxaban Rivaroxaban The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Rivaroxaban.
Ticagrelor Ticagrelor The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Brentuximab vedotin.
Ruxolitinib Ruxolitinib The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Ruxolitinib.
Vandetanib Vandetanib Vandetanib may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Clobazam Clobazam Sulfasalazine may decrease the excretion rate of Clobazam which could result in a higher serum level.
Vemurafenib Vemurafenib Sulfasalazine may decrease the excretion rate of Vemurafenib which could result in a higher serum level.
Vismodegib Vismodegib Vismodegib may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Belatacept Injection Belatacept Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Belatacept.
Basiliximab Injection Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Sulfasalazine.
Deferiprone Deferiprone Sulfasalazine may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Axitinib Axitinib The excretion of Axitinib can be decreased when combined with Sulfasalazine.
Melphalan Injection Melphalan Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Melphalan.
Cabergoline Cabergoline The risk or severity of hypertension can be increased when Cabergoline is combined with Sulfasalazine.
Naloxone Injection Naloxone Injection Sulfasalazine may decrease the excretion rate of Naloxone which could result in a higher serum level.
Ambrisentan Ambrisentan The therapeutic efficacy of Ambrisentan can be decreased when used in combination with Sulfasalazine.
Eculizumab Injection Eculizumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Eculizumab.
Fondaparinux Injection Fondaparinux Injection The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Fondaparinux.
Carfilzomib Injection Carfilzomib Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Carfilzomib.
Iloprost Iloprost The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Iloprost.
Enzalutamide Enzalutamide Sulfasalazine may decrease the excretion rate of Enzalutamide which could result in a higher serum level.
Mirabegron Mirabegron Sulfasalazine may decrease the excretion rate of Mirabegron which could result in a higher serum level.
Regorafenib Regorafenib Regorafenib may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Bosutinib Bosutinib The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Bosutinib.
Corticotropin, Repository Injection Corticotropin, Repository Injection The risk or severity of gastrointestinal irritation can be increased when Sulfasalazine is combined with Corticotropin.
Teriflunomide Teriflunomide The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Teriflunomide.
Lorcaserin Lorcaserin Sulfasalazine may increase the hypoglycemic activities of Mecasermin.
Teduglutide Injection Teduglutide Injection Sulfasalazine may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Icosapent Ethyl Icosapent Ethyl The risk or severity of bleeding can be increased when Sulfasalazine is combined with Icosapent ethyl.
Tofacitinib Tofacitinib The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Tofacitinib.
Alogliptin Alogliptin Sulfasalazine may increase the hypoglycemic activities of Alogliptin.
Dimethyl Fumarate Dimethyl Fumarate The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Dimethyl fumarate.
Ponatinib Ponatinib The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Ponatinib.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Pomalidomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Trastuzumab emtansine.
Apixaban Apixaban The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Apixaban.
Canagliflozin Canagliflozin Sulfasalazine may increase the hypoglycemic activities of Canagliflozin.
Methazolamide Methazolamide The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Methazolamide.
Dabrafenib Dabrafenib Sulfasalazine may decrease the excretion rate of Dabrafenib which could result in a higher serum level.
Trametinib Trametinib Sulfasalazine may decrease the excretion rate of Trametinib which could result in a higher serum level.
Dolutegravir Dolutegravir Sulfasalazine may decrease the excretion rate of Dolutegravir which could result in a higher serum level.
Afatinib Afatinib Sulfasalazine may decrease the excretion rate of Afatinib which could result in a higher serum level.
Levomilnacipran Levomilnacipran The risk or severity of gastrointestinal bleeding can be increased when Levomilnacipran is combined with Sulfasalazine.
Ertapenem Injection Ertapenem Injection Sulfasalazine may decrease the excretion rate of Ertapenem which could result in a higher serum level.
Vortioxetine Vortioxetine Sulfasalazine may decrease the excretion rate of Vortioxetine which could result in a higher serum level.
Ibrutinib Ibrutinib The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Ibrutinib.
Ketorolac Injection Ketorolac Injection The risk or severity of adverse effects can be increased when Ketorolac is combined with Sulfasalazine.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Obinutuzumab.
Simeprevir Simeprevir Sulfasalazine may decrease the excretion rate of Simeprevir which could result in a higher serum level.
Sofosbuvir Sofosbuvir Sulfasalazine may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin Sulfasalazine may increase the hypoglycemic activities of Dapagliflozin.
Apremilast Apremilast The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Apremilast.
Droxidopa Droxidopa Sulfasalazine may decrease the excretion rate of Droxidopa which could result in a higher serum level.
Siltuximab Injection Siltuximab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Siltuximab.
Albiglutide Injection Albiglutide Injection Sulfasalazine may increase the hypoglycemic activities of Albiglutide.
Vedolizumab Injection Vedolizumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Vedolizumab.
Belinostat Injection Belinostat Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Belinostat.
Idelalisib Idelalisib The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Idelalisib.
Testosterone Injection Testosterone Injection Sulfasalazine may decrease the excretion rate of Testosterone which could result in a higher serum level.
Empagliflozin Empagliflozin Sulfasalazine may increase the hypoglycemic activities of Empagliflozin.
Vorapaxar Vorapaxar The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Vorapaxar.
Dulaglutide Injection Dulaglutide Injection Sulfasalazine may increase the hypoglycemic activities of Dulaglutide.
Edoxaban Edoxaban The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Edoxaban.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Peginterferon beta-1a.
Olaparib Olaparib The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Olaparib.
Blinatumomab Injection Blinatumomab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Blinatumomab.
Caspofungin Injection Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Sulfasalazine.
Methamphetamine Methamphetamine Sulfasalazine may decrease the excretion rate of Metamfetamine which could result in a higher serum level.
Tasimelteon Tasimelteon Sulfasalazine may decrease the excretion rate of Tasimelteon which could result in a higher serum level.
Riociguat Riociguat Sulfasalazine may decrease the excretion rate of Riociguat which could result in a higher serum level.
Pirfenidone Pirfenidone The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Pirfenidone.
Secukinumab Injection Secukinumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Secukinumab.
Risperidone Injection Risperidone Injection The risk or severity of hypertension can be increased when Risperidone is combined with Sulfasalazine.
Palbociclib Palbociclib The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Palbociclib.
Insulin Human Inhalation Insulin Human Inhalation Sulfasalazine may increase the hypoglycemic activities of Insulin human.
Lenvatinib Lenvatinib Sulfasalazine may decrease the excretion rate of Lenvatinib which could result in a higher serum level.
Panobinostat Panobinostat The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Panobinostat.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The therapeutic efficacy of Haloperidol can be increased when used in combination with Sulfasalazine.
Amiloride Amiloride The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Amiloride.
Macitentan Macitentan The therapeutic efficacy of Macitentan can be decreased when used in combination with Sulfasalazine.
Flibanserin Flibanserin The risk or severity of hypertension can be increased when Sulfasalazine is combined with Flibanserin.
Rolapitant Rolapitant Rolapitant may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Prednisolone Prednisolone The risk or severity of gastrointestinal irritation can be increased when Sulfasalazine is combined with Prednisolone.
Daclatasvir Daclatasvir Daclatasvir may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Brexpiprazole Brexpiprazole The risk or severity of hypertension can be increased when Sulfasalazine is combined with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of hypertension can be increased when Ziprasidone is combined with Sulfasalazine.
Cariprazine Cariprazine The risk or severity of hypertension can be increased when Sulfasalazine is combined with Cariprazine.
Penicillin G Procaine Injection Penicillin G Procaine Injection Sulfasalazine may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Eluxadoline Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Sulfasalazine.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection Sulfasalazine may increase the hypoglycemic activities of Insulin degludec.
Cobimetinib Cobimetinib The excretion of Cobimetinib can be decreased when combined with Sulfasalazine.
Mepolizumab Injection Mepolizumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Mepolizumab.
Trabectedin Injection Trabectedin Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Trabectedin.
Osimertinib Osimertinib Sulfasalazine may decrease the excretion rate of Osimertinib which could result in a higher serum level.
Alectinib Alectinib Alectinib may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Ixazomib Ixazomib Sulfasalazine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lesinurad Lesinurad Sulfasalazine may decrease the excretion rate of Lesinurad which could result in a higher serum level.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The risk or severity of nephrotoxicity can be increased when Amphotericin B is combined with Sulfasalazine.
Dexamethasone Injection Dexamethasone Injection The risk or severity of gastrointestinal irritation can be increased when Sulfasalazine is combined with Dexamethasone.
Defibrotide Injection Defibrotide Injection The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Defibrotide.
Ixekizumab Injection Ixekizumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Ixekizumab.
Brivaracetam Injection Brivaracetam Injection Sulfasalazine may decrease the excretion rate of Brivaracetam which could result in a higher serum level.
Venetoclax Venetoclax Sulfasalazine may decrease the excretion rate of Venetoclax which could result in a higher serum level.
Cobicistat Cobicistat Cobicistat may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Midodrine Midodrine The risk or severity of hypertension can be increased when Midodrine is combined with Sulfasalazine.
Selexipag Selexipag The therapeutic efficacy of Selexipag can be decreased when used in combination with Sulfasalazine.
Furosemide Injection Furosemide Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Furosemide.
Rucaparib Rucaparib Sulfasalazine may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Lixisenatide Injection Lixisenatide Injection Sulfasalazine may increase the hypoglycemic activities of Lixisenatide.
Brodalumab Injection Brodalumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Brodalumab.
Brigatinib Brigatinib Sulfasalazine may decrease the excretion rate of Brigatinib which could result in a higher serum level.
Doxepin (Insomnia) Doxepin (Insomnia) Sulfasalazine may decrease the excretion rate of Doxepin which could result in a higher serum level.
Deutetrabenazine Deutetrabenazine Sulfasalazine may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level.
Valbenazine Valbenazine Sulfasalazine may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Deflazacort Deflazacort The risk or severity of gastrointestinal irritation can be increased when Sulfasalazine is combined with Deflazacort.
Safinamide Safinamide Safinamide may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Ocrelizumab Injection Ocrelizumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Ocrelizumab.
Naldemedine Naldemedine Sulfasalazine may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Sarilumab Injection Sarilumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Sarilumab.
Guselkumab Injection Guselkumab Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Guselkumab.
Enasidenib Enasidenib Sulfasalazine may decrease the excretion rate of Enasidenib which could result in a higher serum level.
Benznidazole Benznidazole Sulfasalazine may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Copanlisib Injection Copanlisib Injection Sulfasalazine may decrease the excretion rate of Copanlisib which could result in a higher serum level.
Delafloxacin Delafloxacin Sulfasalazine may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib Abemaciclib Sulfasalazine may decrease the excretion rate of Abemaciclib which could result in a higher serum level.
Betrixaban Betrixaban The risk or severity of bleeding can be increased when Betrixaban is combined with Sulfasalazine.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Sulfasalazine.
Letermovir Letermovir Letermovir may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Semaglutide Injection Semaglutide Injection Sulfasalazine may increase the hypoglycemic activities of Semaglutide.
Ertugliflozin Ertugliflozin Sulfasalazine may decrease the excretion rate of Ertugliflozin which could result in a higher serum level.
Buprenorphine Injection Buprenorphine Injection Buprenorphine may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Apalutamide Apalutamide Sulfasalazine may decrease the excretion rate of Apalutamide which could result in a higher serum level.
Penicillamine Penicillamine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Penicillamine.
Fostamatinib Fostamatinib Fostamatinib may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Avatrombopag Avatrombopag Avatrombopag may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Baricitinib Baricitinib The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Baricitinib.
Lofexidine Lofexidine The therapeutic efficacy of Lofexidine can be decreased when used in combination with Sulfasalazine.
Plazomicin Injection Plazomicin Injection Sulfasalazine may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Lusutrombopag Lusutrombopag Sulfasalazine may decrease the excretion rate of Lusutrombopag which could result in a higher serum level.
Elagolix Elagolix The excretion of Elagolix can be decreased when combined with Sulfasalazine.
Cannabidiol Cannabidiol Cannabidiol may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Dacomitinib Dacomitinib Sulfasalazine may decrease the excretion rate of Dacomitinib which could result in a higher serum level.
Duvelisib Duvelisib Sulfasalazine may decrease the excretion rate of Duvelisib which could result in a higher serum level.
Stiripentol Stiripentol Sulfasalazine may decrease the excretion rate of Stiripentol which could result in a higher serum level.
Talazoparib Talazoparib Sulfasalazine may decrease the excretion rate of Talazoparib which could result in a higher serum level.
Gilteritinib Gilteritinib Gilteritinib may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Glasdegib Glasdegib Sulfasalazine may decrease the excretion rate of Glasdegib which could result in a higher serum level.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Paclitaxel.
Prucalopride Prucalopride Sulfasalazine may decrease the excretion rate of Prucalopride which could result in a higher serum level.
Ravulizumab-cwvz Injection Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Ravulizumab.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Emapalumab.
Siponimod Siponimod The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Siponimod.
Acyclovir Ophthalmic Acyclovir Ophthalmic Sulfasalazine may decrease the excretion rate of Acyclovir which could result in a higher serum level.
Caplacizumab-yhdp Injection Caplacizumab-yhdp Injection The risk or severity of bleeding can be increased when Sulfasalazine is combined with Caplacizumab.
Risankizumab-rzaa Injection Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Risankizumab.
Alpelisib Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Sulfasalazine.
Cladribine Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Sulfasalazine.
Solriamfetol Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Sulfasalazine.
Darolutamide Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Sulfasalazine.
Istradefylline Istradefylline Istradefylline may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Pitolisant Pitolisant The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Pitolisant.
Fedratinib Fedratinib Fedratinib may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Phenytoin Injection Phenytoin Injection The serum concentration of Phenytoin can be increased when it is combined with Sulfasalazine.
Fosphenytoin Injection Fosphenytoin Injection The protein binding of Fosphenytoin can be decreased when combined with Sulfasalazine.
Lasmiditan Lasmiditan The serum concentration of Sulfasalazine can be increased when it is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Sulfasalazine.
Tazemetostat Tazemetostat Sulfasalazine may decrease the excretion rate of Tazemetostat which could result in a higher serum level.
Bempedoic Acid Bempedoic Acid The excretion of Bempedoic acid can be decreased when combined with Sulfasalazine.
Ozanimod Ozanimod Sulfasalazine may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Selumetinib Selumetinib Sulfasalazine may decrease the excretion rate of Selumetinib which could result in a higher serum level.
Rimegepant Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Sulfasalazine.
Tucatinib Tucatinib Sulfasalazine may decrease the excretion rate of Tucatinib which could result in a higher serum level.
Remdesivir Injection Remdesivir Injection The excretion of Remdesivir can be decreased when combined with Sulfasalazine.
Ripretinib Ripretinib Sulfasalazine may decrease the excretion rate of Ripretinib which could result in a higher serum level.
Selpercatinib Selpercatinib The risk or severity of hypertension can be increased when Sulfasalazine is combined with Selpercatinib.
Capmatinib Capmatinib The serum concentration of Sulfasalazine can be increased when it is combined with Capmatinib.
Fostemsavir Fostemsavir Sulfasalazine may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The excretion of Belantamab mafodotin can be decreased when combined with Sulfasalazine.
Pralsetinib Pralsetinib Sulfasalazine may decrease the excretion rate of Pralsetinib which could result in a higher serum level.
Naxitamab-gqgk Injection Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Sulfasalazine is combined with Naxitamab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The risk or severity of hyperkalemia can be increased when Sulfasalazine is combined with Drospirenone.
Viloxazine Viloxazine Sulfasalazine may decrease the excretion rate of Viloxazine which could result in a higher serum level.
Tobramycin Injection Tobramycin Injection Sulfasalazine may decrease the excretion rate of Tobramycin which could result in a higher serum level.
Fenoprofen Fenoprofen The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Fenoprofen.
Indomethacin Indomethacin The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Indomethacin.
Mefenamic Acid Mefenamic Acid The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Mefenamic acid.
Naproxen Naproxen The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Naproxen.
Tolmetin Tolmetin The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Tolmetin.
Sulindac Sulindac The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Sulindac.
Trazodone Trazodone The risk or severity of gastrointestinal bleeding can be increased when Trazodone is combined with Sulfasalazine.
Isotretinoin Isotretinoin Sulfasalazine may decrease the excretion rate of Isotretinoin which could result in a higher serum level.
Sucralfate Sucralfate Sulfasalazine may decrease the excretion rate of Sucralfate which could result in a higher serum level.
Hydroxyurea Hydroxyurea The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Hydroxyurea.
Floxuridine Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Sulfasalazine.
Phenobarbital Phenobarbital The risk or severity of methemoglobinemia can be increased when Sulfasalazine is combined with Phenobarbital.
Metaxalone Metaxalone Sulfasalazine may decrease the excretion rate of Metaxalone which could result in a higher serum level.
Methotrexate Injection Methotrexate Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Methotrexate.
Methsuximide Methsuximide The risk or severity of hyperkalemia can be increased when Sulfasalazine is combined with Methsuximide.
Diethylpropion Diethylpropion The risk or severity of hypertension can be increased when Sulfasalazine is combined with Diethylpropion.
Chlorpromazine Chlorpromazine Sulfasalazine may decrease the excretion rate of Chlorpromazine which could result in a higher serum level.
Diazepam Diazepam Sulfasalazine may decrease the excretion rate of Diazepam which could result in a higher serum level.
Oxazepam Oxazepam Sulfasalazine may decrease the excretion rate of Oxazepam which could result in a higher serum level.
Flurazepam Flurazepam Sulfasalazine may decrease the excretion rate of Flurazepam which could result in a higher serum level.
Clorazepate Clorazepate Sulfasalazine may decrease the excretion rate of Clorazepic acid which could result in a higher serum level.
Lorazepam Lorazepam Sulfasalazine may decrease the excretion rate of Lorazepam which could result in a higher serum level.
Phenoxybenzamine Phenoxybenzamine The therapeutic efficacy of Phenoxybenzamine can be decreased when used in combination with Sulfasalazine.
Carmustine Carmustine The risk or severity of adverse effects can be increased when Carmustine is combined with Sulfasalazine.
Amantadine Amantadine Sulfasalazine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Codeine Codeine Sulfasalazine may decrease the excretion rate of Codeine which could result in a higher serum level.
Bromocriptine Bromocriptine Sulfasalazine may increase the hypoglycemic activities of Bromocriptine.
Metaproterenol Metaproterenol The risk or severity of hypertension can be increased when Sulfasalazine is combined with Orciprenaline.
Tranylcypromine Tranylcypromine The risk or severity of hypertension can be increased when Tranylcypromine is combined with Sulfasalazine.
Phenelzine Phenelzine Sulfasalazine may decrease the excretion rate of Phenelzine which could result in a higher serum level.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Procarbazine.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of hypertension can be increased when Sulfasalazine is combined with Ergoloid mesylate.
Tetracycline Tetracycline Sulfasalazine may decrease the excretion rate of Tetracycline which could result in a higher serum level.
Thioguanine Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Sulfasalazine.
Thioridazine Thioridazine The risk or severity of hypertension can be increased when Thioridazine is combined with Sulfasalazine.
Trifluoperazine Trifluoperazine The risk or severity of hypertension can be increased when Sulfasalazine is combined with Trifluoperazine.
Bleomycin Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Sulfasalazine.
Dapsone Dapsone The risk or severity of methemoglobinemia can be increased when Dapsone is combined with Sulfasalazine.
Sulfadiazine Sulfadiazine The risk or severity of methemoglobinemia can be increased when Sulfasalazine is combined with Sulfadiazine.
Methadone Methadone Sulfasalazine may decrease the excretion rate of Methadone which could result in a higher serum level.
Benztropine Benztropine Sulfasalazine may decrease the excretion rate of Benzatropine which could result in a higher serum level.
Colestipol Colestipol Colestipol can cause a decrease in the absorption of Sulfasalazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Maprotiline Maprotiline Sulfasalazine may decrease the excretion rate of Maprotiline which could result in a higher serum level.
Ibuprofen Ibuprofen The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Ibuprofen.
Azathioprine Azathioprine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Azathioprine.
Phentermine Phentermine The risk or severity of hypertension can be increased when Phentermine is combined with Sulfasalazine.
Methylphenidate Methylphenidate Sulfasalazine may decrease the excretion rate of Methylphenidate which could result in a higher serum level.
Amoxapine Amoxapine The risk or severity of hypertension can be increased when Amoxapine is combined with Sulfasalazine.
Hydrocortisone Hydrocortisone The risk or severity of gastrointestinal irritation can be increased when Hydrocortisone is combined with Sulfasalazine.
Lomustine Lomustine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Lomustine.
Doxorubicin Doxorubicin The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Doxorubicin.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Cytarabine.
Mechlorethamine Mechlorethamine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Mechlorethamine.
Dactinomycin Dactinomycin The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Dactinomycin.
Phenazopyridine Phenazopyridine The risk or severity of methemoglobinemia can be increased when Sulfasalazine is combined with Phenazopyridine.
Carbamazepine Carbamazepine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Carbamazepine.
Methyldopa Methyldopa The therapeutic efficacy of Methyldopa can be decreased when used in combination with Sulfasalazine.
Clonidine Clonidine The therapeutic efficacy of Clonidine can be decreased when used in combination with Sulfasalazine.
Prazosin Prazosin Sulfasalazine may decrease the excretion rate of Prazosin which could result in a higher serum level.
Hydralazine Hydralazine Sulfasalazine may decrease the antihypertensive activities of Hydralazine.
Cimetidine Cimetidine Sulfasalazine may decrease the excretion rate of Cimetidine which could result in a higher serum level.
Gentamicin Injection Gentamicin Injection Sulfasalazine may decrease the excretion rate of Gentamicin which could result in a higher serum level.
Warfarin Warfarin The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Warfarin.
Clonazepam Clonazepam Sulfasalazine may decrease the excretion rate of Clonazepam which could result in a higher serum level.
Loperamide Loperamide The risk or severity of hyperkalemia can be increased when Sulfasalazine is combined with Loperamide.
Promethazine Promethazine Sulfasalazine may decrease the excretion rate of Promethazine which could result in a higher serum level.
Meclofenamate Meclofenamate The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Meclofenamic acid.
Daunorubicin Daunorubicin The risk or severity of adverse effects can be increased when Daunorubicin is combined with Sulfasalazine.
Nitrofurantoin Nitrofurantoin The risk or severity of methemoglobinemia can be increased when Sulfasalazine is combined with Nitrofurantoin.
Digoxin Digoxin The serum concentration of Digoxin can be decreased when it is combined with Sulfasalazine.
Chloroquine Chloroquine The risk or severity of methemoglobinemia can be increased when Sulfasalazine is combined with Chloroquine.
Quinine Quinine The risk or severity of methemoglobinemia can be increased when Sulfasalazine is combined with Quinine.
Ethosuximide Ethosuximide The risk or severity of hyperkalemia can be increased when Ethosuximide is combined with Sulfasalazine.
Triamterene Triamterene The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Triamterene.
Sulfinpyrazone Sulfinpyrazone The risk or severity of bleeding can be increased when Sulfasalazine is combined with Sulfinpyrazone.
Chlorothiazide Chlorothiazide The therapeutic efficacy of Chlorothiazide can be decreased when used in combination with Sulfasalazine.
Chlorthalidone Chlorthalidone The therapeutic efficacy of Chlorthalidone can be decreased when used in combination with Sulfasalazine.
Metolazone Metolazone The therapeutic efficacy of Metolazone can be decreased when used in combination with Sulfasalazine.
Secobarbital Secobarbital Sulfasalazine may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Desipramine Desipramine Sulfasalazine may decrease the excretion rate of Desipramine which could result in a higher serum level.
Amitriptyline Amitriptyline Amitriptyline may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Imipramine Imipramine Imipramine may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Probenecid Probenecid Probenecid may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Quinidine Quinidine Sulfasalazine may decrease the excretion rate of Quinidine which could result in a higher serum level.
Procainamide Procainamide Sulfasalazine may decrease the excretion rate of Procainamide which could result in a higher serum level.
Isoniazid Isoniazid Sulfasalazine may decrease the excretion rate of Isoniazid which could result in a higher serum level.
Pyrazinamide Pyrazinamide Sulfasalazine may decrease the excretion rate of Pyrazinamide which could result in a higher serum level.
Rifampin Rifampin The excretion of Rifampicin can be decreased when combined with Sulfasalazine.
Disopyramide Disopyramide Sulfasalazine may increase the hypoglycemic activities of Disopyramide.
Valproic Acid Valproic Acid The serum concentration of Valproic acid can be increased when it is combined with Sulfasalazine.
Tamoxifen Tamoxifen Sulfasalazine may decrease the excretion rate of Tamoxifen which could result in a higher serum level.
Mitomycin Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with Sulfasalazine.
Butabarbital Butabarbital Sulfasalazine may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Levothyroxine Levothyroxine The therapeutic efficacy of Levothyroxine can be increased when used in combination with Sulfasalazine.
Liothyronine Liothyronine Sulfasalazine may decrease the excretion rate of Liothyronine which could result in a higher serum level.
Methimazole Methimazole The risk or severity of adverse effects can be increased when Methimazole is combined with Sulfasalazine.
Propylthiouracil Propylthiouracil The risk or severity of adverse effects can be increased when Propylthiouracil is combined with Sulfasalazine.
Chlorpropamide Chlorpropamide Sulfasalazine may increase the hypoglycemic activities of Chlorpropamide.
Tolbutamide Tolbutamide Sulfasalazine may increase the hypoglycemic activities of Tolbutamide.
Tolazamide Tolazamide Sulfasalazine may increase the hypoglycemic activities of Tolazamide.
Dinoprostone Dinoprostone The excretion of Dinoprostone can be decreased when combined with Sulfasalazine.
Baclofen Baclofen Sulfasalazine may decrease the excretion rate of Baclofen which could result in a higher serum level.
Ethambutol Ethambutol Sulfasalazine may decrease the excretion rate of Ethambutol which could result in a higher serum level.
Methyclothiazide Methyclothiazide The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Sulfasalazine.
Hydrochlorothiazide Hydrochlorothiazide The therapeutic efficacy of Hydrochlorothiazide can be decreased when used in combination with Sulfasalazine.
Dantrolene Dantrolene The risk or severity of hyperkalemia can be increased when Sulfasalazine is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone Sulfasalazine may decrease the excretion rate of Chlorzoxazone which could result in a higher serum level.
Pyridoxine Pyridoxine Sulfasalazine may decrease the excretion rate of Pyridoxine which could result in a higher serum level.
Folic Acid Folic Acid The serum concentration of Folic acid can be decreased when it is combined with Sulfasalazine.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) Sulfasalazine may decrease the antihypertensive activities of Propranolol.
Minoxidil Minoxidil The therapeutic efficacy of Minoxidil can be decreased when used in combination with Sulfasalazine.
Pseudoephedrine Pseudoephedrine The risk or severity of hypertension can be increased when Sulfasalazine is combined with Pseudoephedrine.
Nortriptyline Nortriptyline The risk or severity of hypertension can be increased when Nortriptyline is combined with Sulfasalazine.
Spironolactone Spironolactone The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Spironolactone.
Amphotericin B Injection Amphotericin B Injection The risk or severity of nephrotoxicity can be increased when Amphotericin B is combined with Sulfasalazine.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Mercaptopurine.
Phytonadione Phytonadione Sulfasalazine may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
Amikacin Injection Amikacin Injection Sulfasalazine may decrease the excretion rate of Amikacin which could result in a higher serum level.
Nadolol Nadolol Sulfasalazine may decrease the antihypertensive activities of Nadolol.
Cholestyramine Resin Cholestyramine Resin Cholestyramine can cause a decrease in the absorption of Sulfasalazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Allopurinol Allopurinol Sulfasalazine may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Flavoxate Flavoxate Sulfasalazine may decrease the excretion rate of Flavoxate which could result in a higher serum level.
Fluorouracil Injection Fluorouracil Injection The risk or severity of adverse effects can be increased when Fluorouracil is combined with Sulfasalazine.
Colchicine Colchicine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Colchicine.
Cefaclor Cefaclor Sulfasalazine may decrease the excretion rate of Cefaclor which could result in a higher serum level.
Cefadroxil Cefadroxil Sulfasalazine may decrease the excretion rate of Cefadroxil which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection The risk or severity of nephrotoxicity can be increased when Sulfasalazine is combined with Cefazolin.
Cephalexin Cephalexin Sulfasalazine may decrease the excretion rate of Cephalexin which could result in a higher serum level.
Cefoxitin Injection Cefoxitin Injection The risk or severity of nephrotoxicity can be increased when Sulfasalazine is combined with Cefoxitin.
Dacarbazine Dacarbazine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Dacarbazine.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Acetazolamide.
Cefotaxime Injection Cefotaxime Injection The risk or severity of nephrotoxicity can be increased when Cefotaxime is combined with Sulfasalazine.
Calcitonin Salmon Injection Calcitonin Salmon Injection Sulfasalazine may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Sulfasalazine.
Ketoconazole Ketoconazole The risk or severity of hyperkalemia can be increased when Sulfasalazine is combined with Ketoconazole.
Pyrantel Pyrantel Sulfasalazine may decrease the excretion rate of Pyrantel which could result in a higher serum level.
Thiotepa Injection Thiotepa Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Thiotepa.
Vincristine Injection Vincristine Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Sulfasalazine.
Captopril Captopril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Captopril.
Dipyridamole Dipyridamole The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Dipyridamole.
Isoxsuprine Isoxsuprine The risk or severity of hypertension can be increased when Sulfasalazine is combined with Isoxsuprine.
Vinblastine Vinblastine The risk or severity of adverse effects can be increased when Vinblastine is combined with Sulfasalazine.
Ethacrynic Acid Ethacrynic Acid The therapeutic efficacy of Etacrynic acid can be decreased when used in combination with Sulfasalazine.
Colistimethate Injection Colistimethate Injection The risk or severity of nephrotoxicity can be increased when Sulfasalazine is combined with Colistimethate.
Metoprolol Metoprolol Sulfasalazine may decrease the antihypertensive activities of Metoprolol.
Aspirin Aspirin The therapeutic efficacy of Acetylsalicylic acid can be decreased when used in combination with Sulfasalazine.
Salsalate Salsalate The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Salsalate.
Chlorambucil Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Sulfasalazine.
Alprazolam Alprazolam Sulfasalazine may decrease the excretion rate of Alprazolam which could result in a higher serum level.
Temazepam Temazepam Sulfasalazine may decrease the excretion rate of Temazepam which could result in a higher serum level.
Triazolam Triazolam Sulfasalazine may decrease the excretion rate of Triazolam which could result in a higher serum level.
Dicyclomine Dicyclomine Sulfasalazine may decrease the excretion rate of Dicyclomine which could result in a higher serum level.
Propantheline Propantheline Sulfasalazine may decrease the excretion rate of Propantheline which could result in a higher serum level.
Trimethoprim Trimethoprim Sulfasalazine may decrease the excretion rate of Trimethoprim which could result in a higher serum level.
Diltiazem Diltiazem The risk or severity of bleeding can be increased when Diltiazem is combined with Sulfasalazine.
Nifedipine Nifedipine Sulfasalazine may decrease the excretion rate of Nifedipine which could result in a higher serum level.
Timolol Timolol Sulfasalazine may decrease the antihypertensive activities of Timolol.
Verapamil Verapamil The risk or severity of bleeding can be increased when Verapamil is combined with Sulfasalazine.
Atenolol Atenolol Sulfasalazine may decrease the antihypertensive activities of Atenolol.
Pindolol Pindolol Sulfasalazine may decrease the antihypertensive activities of Pindolol.
Cisplatin Injection Cisplatin Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Cisplatin.
Diflunisal Diflunisal The therapeutic efficacy of Diflunisal can be decreased when used in combination with Sulfasalazine.
Piroxicam Piroxicam The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Piroxicam.
Bumetanide Bumetanide The therapeutic efficacy of Bumetanide can be decreased when used in combination with Sulfasalazine.
Streptozocin Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with Sulfasalazine.
Etoposide Etoposide The risk or severity of adverse effects can be increased when Etoposide is combined with Sulfasalazine.
Glyburide Glyburide Sulfasalazine may increase the hypoglycemic activities of Glyburide.
Glipizide Glipizide Sulfasalazine may increase the hypoglycemic activities of Glipizide.
Indapamide Indapamide The therapeutic efficacy of Indapamide can be decreased when used in combination with Sulfasalazine.
Amoxicillin Amoxicillin Sulfasalazine may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Sulfasalazine may decrease the excretion rate of Oxacillin which could result in a higher serum level.
Pentoxifylline Pentoxifylline The risk or severity of bleeding can be increased when Sulfasalazine is combined with Pentoxifylline.
Pentamidine Injection Pentamidine Injection Sulfasalazine may increase the hypoglycemic activities of Pentamidine.
Ceftriaxone Injection Ceftriaxone Injection Sulfasalazine may decrease the excretion rate of Ceftriaxone which could result in a higher serum level.
Labetalol Labetalol Sulfasalazine may decrease the antihypertensive activities of Labetalol.
Auranofin Auranofin Sulfasalazine may decrease the excretion rate of Auranofin which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection Sulfasalazine may decrease the excretion rate of Leuprolide which could result in a higher serum level.
Gemfibrozil Gemfibrozil Sulfasalazine may decrease the excretion rate of Gemfibrozil which could result in a higher serum level.
Guanabenz Guanabenz The therapeutic efficacy of Guanabenz can be decreased when used in combination with Sulfasalazine.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic The risk or severity of nephrotoxicity can be increased when Adefovir dipivoxil is combined with Sulfasalazine.
Ceftazidime Injection Ceftazidime Injection Sulfasalazine may decrease the excretion rate of Ceftazidime which could result in a higher serum level.
Ketoprofen Ketoprofen The risk or severity of bleeding and gastrointestinal bleeding can be increased when Sulfasalazine is combined with Ketoprofen.
Cefotetan Injection Cefotetan Injection Sulfasalazine may decrease the excretion rate of Cefotetan which could result in a higher serum level.
Enalapril Enalapril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Enalapril.
Flurbiprofen Flurbiprofen The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Flurbiprofen.
Amiodarone Amiodarone The risk or severity of hyperkalemia can be increased when Sulfasalazine is combined with Amiodarone.
Aztreonam Injection Aztreonam Injection Sulfasalazine may decrease the excretion rate of Aztreonam which could result in a higher serum level.
Buspirone Buspirone Sulfasalazine may decrease the excretion rate of Buspirone which could result in a higher serum level.
Lovastatin Lovastatin The excretion of Lovastatin can be decreased when combined with Sulfasalazine.
Ciprofloxacin Ciprofloxacin Sulfasalazine may decrease the excretion rate of Ciprofloxacin which could result in a higher serum level.
Mesalamine Mesalamine The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Mesalazine.
Diclofenac Diclofenac The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Diclofenac.
Fluoxetine Fluoxetine The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Sulfasalazine.
Nimodipine Nimodipine The therapeutic efficacy of Nimodipine can be decreased when used in combination with Sulfasalazine.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Sulfasalazine.
Clozapine Clozapine Sulfasalazine may decrease the excretion rate of Clozapine which could result in a higher serum level.
Estazolam Estazolam Sulfasalazine may decrease the excretion rate of Estazolam which could result in a higher serum level.
Idarubicin Idarubicin The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Idarubicin.
Ofloxacin Ofloxacin Sulfasalazine may increase the neuroexcitatory activities of Ofloxacin.
Didanosine Didanosine Sulfasalazine may decrease the excretion rate of Didanosine which could result in a higher serum level.
Fludarabine Injection Fludarabine Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Fludarabine.
Pentostatin Injection Pentostatin Injection The risk or severity of adverse effects can be increased when Pentostatin is combined with Sulfasalazine.
Benazepril Benazepril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Benazepril.
Etodolac Etodolac The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Etodolac.
Felodipine Felodipine The therapeutic efficacy of Felodipine can be decreased when used in combination with Sulfasalazine.
Fosinopril Fosinopril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Fosinopril.
Nabumetone Nabumetone The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Nabumetone.
Pravastatin Pravastatin Pravastatin may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Quinapril Quinapril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Quinapril.
Ramipril Ramipril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Ramipril.
Simvastatin Simvastatin The excretion of Simvastatin can be decreased when combined with Sulfasalazine.
Amlodipine Amlodipine Sulfasalazine may decrease the antihypertensive activities of Amlodipine.
Teniposide Injection Teniposide Injection The risk or severity of adverse effects can be increased when Teniposide is combined with Sulfasalazine.
Itraconazole Itraconazole The risk or severity of hyperkalemia can be increased when Sulfasalazine is combined with Itraconazole.
Lisinopril Lisinopril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Lisinopril.
Oxaprozin Oxaprozin The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Oxaprozin.
Sotalol Sotalol Sulfasalazine may decrease the antihypertensive activities of Sotalol.
Bisoprolol Bisoprolol Sulfasalazine may decrease the antihypertensive activities of Bisoprolol.
Doxazosin Doxazosin The therapeutic efficacy of Doxazosin can be decreased when used in combination with Sulfasalazine.
Terazosin Terazosin The therapeutic efficacy of Terazosin can be decreased when used in combination with Sulfasalazine.
Isradipine Isradipine Sulfasalazine may decrease the excretion rate of Isradipine which could result in a higher serum level.
Omeprazole Omeprazole Omeprazole may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Fluvastatin Fluvastatin The excretion of Fluvastatin can be decreased when combined with Sulfasalazine.
Venlafaxine Venlafaxine Venlafaxine may increase the antiplatelet activities of Sulfasalazine.
Fluvoxamine Fluvoxamine The risk or severity of gastrointestinal bleeding can be increased when Sulfasalazine is combined with Fluvoxamine.
Nefazodone Nefazodone The risk or severity of gastrointestinal bleeding can be increased when Sulfasalazine is combined with Nefazodone.
Lamotrigine Lamotrigine Sulfasalazine may decrease the excretion rate of Lamotrigine which could result in a higher serum level.
Losartan Losartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Losartan is combined with Sulfasalazine.
Valacyclovir Valacyclovir Sulfasalazine may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Tramadol Tramadol Sulfasalazine may decrease the excretion rate of Tramadol which could result in a higher serum level.
Vinorelbine Injection Vinorelbine Injection The risk or severity of adverse effects can be increased when Vinorelbine is combined with Sulfasalazine.
Carboplatin Injection Carboplatin Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Carboplatin.
Moexipril Moexipril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Moexipril.
Lansoprazole Lansoprazole Lansoprazole may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Ifosfamide Injection Ifosfamide Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Ifosfamide.
Pegaspargase Injection Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Sulfasalazine.
Nicardipine Nicardipine The therapeutic efficacy of Nicardipine can be decreased when used in combination with Sulfasalazine.
Bupropion Bupropion Sulfasalazine may decrease the excretion rate of Bupropion which could result in a higher serum level.
Ticlopidine Ticlopidine The risk or severity of bleeding can be increased when Sulfasalazine is combined with Ticlopidine.
Saquinavir Saquinavir Saquinavir may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Metformin Metformin Sulfasalazine may increase the hypoglycemic activities of Metformin.
Dalteparin Injection Dalteparin Injection The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Dalteparin.
Nisoldipine Nisoldipine Sulfasalazine may decrease the excretion rate of Nisoldipine which could result in a higher serum level.
Lamivudine Lamivudine Sulfasalazine may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole Riluzole Sulfasalazine may decrease the excretion rate of Riluzole which could result in a higher serum level.
Acarbose Acarbose Sulfasalazine may increase the hypoglycemic activities of Acarbose.
Glimepiride Glimepiride Sulfasalazine may increase the hypoglycemic activities of Glimepiride.
Gemcitabine Injection Gemcitabine Injection The risk or severity of adverse effects can be increased when Gemcitabine is combined with Sulfasalazine.
Ritonavir Ritonavir Ritonavir may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Docetaxel Injection Docetaxel Injection The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Docetaxel.
Cidofovir Injection Cidofovir Injection Sulfasalazine may decrease the excretion rate of Cidofovir which could result in a higher serum level.
Meropenem Injection Meropenem Injection Sulfasalazine may decrease the excretion rate of Meropenem which could result in a higher serum level.
Clomipramine Clomipramine Sulfasalazine may decrease the excretion rate of Clomipramine which could result in a higher serum level.
Fosfomycin Fosfomycin Sulfasalazine may decrease the excretion rate of Fosfomycin which could result in a higher serum level.
Mirtazapine Mirtazapine The risk or severity of hypertension can be increased when Mirtazapine is combined with Sulfasalazine.
Trandolapril Trandolapril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Trandolapril.
Topiramate Topiramate Sulfasalazine may decrease the excretion rate of Topiramate which could result in a higher serum level.
Valsartan Valsartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Valsartan is combined with Sulfasalazine.
Insulin Lispro Injection Insulin Lispro Injection Sulfasalazine may increase the hypoglycemic activities of Insulin lispro.
Pramipexole Pramipexole Sulfasalazine may decrease the excretion rate of Pramipexole which could result in a higher serum level.
Donepezil Donepezil Sulfasalazine may decrease the excretion rate of Donepezil which could result in a higher serum level.
Nelfinavir Nelfinavir Nelfinavir may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Fexofenadine Fexofenadine The excretion of Fexofenadine can be decreased when combined with Sulfasalazine.
Carvedilol Carvedilol Sulfasalazine may decrease the antihypertensive activities of Carvedilol.
Nilutamide Nilutamide Sulfasalazine may decrease the excretion rate of Nilutamide which could result in a higher serum level.
Flutamide Flutamide The risk or severity of methemoglobinemia can be increased when Sulfasalazine is combined with Flutamide.
Selegiline Selegiline The risk or severity of hypertension can be increased when Sulfasalazine is combined with Selegiline.
Sertraline Sertraline The risk or severity of bleeding can be increased when Sertraline is combined with Sulfasalazine.
Propafenone Propafenone Sulfasalazine may decrease the antihypertensive activities of Propafenone.
Raloxifene Raloxifene Sulfasalazine may decrease the excretion rate of Raloxifene which could result in a higher serum level.
Irbesartan Irbesartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Irbesartan is combined with Sulfasalazine.
Tamsulosin Tamsulosin Sulfasalazine may decrease the excretion rate of Tamsulosin which could result in a higher serum level.
Finasteride Finasteride The risk or severity of hypertension can be increased when Sulfasalazine is combined with Finasteride.
Quetiapine Quetiapine Sulfasalazine may decrease the excretion rate of Quetiapine which could result in a higher serum level.
Cefepime Injection Cefepime Injection The risk or severity of nephrotoxicity can be increased when Sulfasalazine is combined with Cefepime.
Cefprozil Cefprozil The risk or severity of nephrotoxicity can be increased when Sulfasalazine is combined with Cefprozil.
Cefpodoxime Cefpodoxime The risk or severity of nephrotoxicity can be increased when Sulfasalazine is combined with Cefpodoxime.
Cetirizine Cetirizine Sulfasalazine may decrease the excretion rate of Cetirizine which could result in a higher serum level.
Paroxetine Paroxetine The risk or severity of gastrointestinal bleeding can be increased when Paroxetine is combined with Sulfasalazine.
Tolcapone Tolcapone Sulfasalazine may decrease the excretion rate of Tolcapone which could result in a higher serum level.
Citalopram Citalopram The risk or severity of gastrointestinal bleeding can be increased when Citalopram is combined with Sulfasalazine.
Capecitabine Capecitabine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Capecitabine.
Abacavir Abacavir Sulfasalazine may decrease the excretion rate of Abacavir which could result in a higher serum level.
Pioglitazone Pioglitazone Sulfasalazine may increase the hypoglycemic activities of Pioglitazone.
Trastuzumab Injection Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Sulfasalazine.
Celecoxib Celecoxib The risk or severity of adverse effects can be increased when Celecoxib is combined with Sulfasalazine.
Rosiglitazone Rosiglitazone Sulfasalazine may increase the hypoglycemic activities of Rosiglitazone.
Tolterodine Tolterodine Sulfasalazine may decrease the excretion rate of Tolterodine which could result in a higher serum level.
Thalidomide Thalidomide The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Thalidomide.
Oseltamivir Oseltamivir Sulfasalazine may decrease the excretion rate of Oseltamivir which could result in a higher serum level.
Colesevelam Colesevelam Colesevelam can cause a decrease in the absorption of Sulfasalazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Balsalazide Balsalazide The therapeutic efficacy of Balsalazide can be decreased when used in combination with Sulfasalazine.
Nateglinide Nateglinide Sulfasalazine may increase the hypoglycemic activities of Nateglinide.
Rabeprazole Rabeprazole Rabeprazole may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.

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