Teriflunomide

Generic name: Pronounced as (ter'' i floo' noe mide)
Brand names
  • Aubagio®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 01/15/2021

Teriflunomide may cause serious or life-threatening liver damage, that may require a liver transplant. The risk of liver damage may be increased in people taking other medications known to cause liver damage, and in people who already have liver disease. Tell your doctor if you have liver disease. Your doctor may tell you not to take teriflunomide. Tell your doctor and pharmacist about all the medications you are taking so they can check whether any of your medications may increase the risk that you will develop liver damage during your treatment with teriflunomide. If you experience any of the following symptoms, call your doctor immediately: nausea, vomiting, extreme tiredness, unusual bleeding or bruising, lack of energy, loss of appetite, pain in the upper right part of the stomach, yellowing of the skin or eyes, dark-colored urine, or flu-like symptoms. If liver damage is suspected, your doctor may stop teriflunomide and may give you a treatment that will help to remove teriflunomide more quickly from your body.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests before you begin your treatment and regularly during your treatment to check your body's response to teriflunomide.

Do not take teriflunomide if you are pregnant or plan to become pregnant. Teriflunomide may harm the fetus. You should not begin taking teriflunomide until you have taken a pregnancy test with negative results and your doctor tells you that you are not pregnant. You must use an effective method of birth control before you begin taking teriflunomide, during your treatment with teriflunomide, and for up to 2 years after treatment, until blood tests show that you have low enough levels of teriflunomide in your blood. If your period is late, you miss a period, or you think you may be pregnant during your treatment with teriflunomide or for 2 years after your treatment, call your doctor immediately. If you are a male and your partner can become pregnant, you and your partner should use effective birth control during your treatment. If you or your partner plan to become pregnant or can become pregnant, talk to your doctor about a treatment that will help to remove teriflunomide more quickly from your body after you stop taking the medication.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with teriflunomide and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.

Talk to your doctor about the risks of taking teriflunomide.

Teriflunomide is used to treat adults with various forms of multiple sclerosis (MS; a disease in which the nerves do not function properly and people may experience weakness, numbness, loss of muscle coordination, and problems with vision, speech, and bladder control) including:

  • clinically isolated syndrome (CIS; nerve symptom episodes that last at least 24 hours),

  • relapsing-remitting forms (course of disease where symptoms flare up from time to time), or

  • secondary progressive forms (course of disease where relapses occur more often).

Teriflunomide is in a class of medications called immunomodulatory agents. It is thought to work by decreasing inflammation and decreasing the action of immune cells that may cause nerve damage.

Teriflunomide comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take teriflunomide at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take teriflunomide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Teriflunomide may help to control the symptoms of multiple sclerosis, but does not cure it. Continue to take teriflunomide even if you feel well. Do not stop taking teriflunomide without talking to your doctor.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking teriflunomide,

  • tell your doctor and pharmacist if you are allergic to teriflunomide (rash, hives, shortness of breath, swelling of the face, eyes, mouth, throat, tongue, lips, hands, feet, ankles, or lower legs), leflunomide (Arava), any other medications, or any of the ingredients in teriflunomide tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.

  • tell your doctor if you are taking leflunomide (Arava). Your doctor will probably tell you not to take teriflunomide if you are taking this medication.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: alosetron (Lotronex); anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); atorvastatin (Lipitor, in Caduet); cefaclor; cimetidine (Tagamet); ciprofloxacin (Cipro); duloxetine (Cymbalta); eltrombopag (Promacta); furosemide (Lasix); gefitinib (Iressa); ketoprofen; medications that can cause nerve damage such as medications for cancer, HIV, or AIDS; other medications that suppress the immune system such as azathioprine (Azasan, Imuran), cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), and tacrolimus (Astagraf, Envarsus XR, Prograf); methotrexate (Otrexup, Rasuvo, Trexall); mitoxantrone; nateglinide (Starlix); oral contraceptives (birth control pills); paclitaxel (Abraxane, Taxol); penicillin G; pioglitazone (Actos, in Actoplus Met, in Duetact); pravastatin (Pravachol); repaglinide (Prandin, in Prandimet); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); rosiglitazone (Avandia); rosuvastatin (Crestor); simvastatin (Zocor, in Vytorin); theophylline (Elixophyllin, Theo-24, Uniphyl, others); tizanidine (Zanaflex); and zidovudine (Retrovir, in Combivir, in Trizivir). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with teriflunomide, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you have an infection now, including an ongoing infection that does not go away, or if you have or have ever had a serious skin reaction after you took another medication; diabetes; breathing problems; cancer or other conditions affecting the bone marrow or the immune system; high blood pressure; peripheral neuropathy (numbness, burning or tingling in the hands or feet that feels different from your MS symptoms); or kidney disease.

  • tell your doctor if you are breast-feeding. Do not breastfeed while taking teriflunomide.

  • if your partner plans to become pregnant, you should talk to your doctor about stopping teriflunomide and receiving a treatment to help remove this medication from your body more quickly. If your partner does not plan to become pregnant, you and your partner should use an effective method of birth control during your treatment with teriflunomide and for up to 2 years after treatment, until blood tests show that you have low enough levels of teriflunomide in your blood.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking teriflunomide.

  • you may already be infected with tuberculosis (TB; a serious lung infection) but not have any symptoms of the disease. Tell your doctor if you have or have ever had TB, if you have lived in or visited a country where TB is common, or if you have been around someone who has or has ever had TB. Before you begin your treatment with teriflunomide, your doctor will perform a skin test to see if you have TB. If you do have TB, your doctor will treat this infection before you begin taking teriflunomide.

  • do not have any vaccinations without talking to your doctor while you are taking teriflunomide and for 6 months after you stop taking it.

  • you should know that teriflunomide may cause high blood pressure. You should have your blood pressure checked before starting treatment and regularly while you are taking this medication.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Teriflunomide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • hair loss

    • diarrhea

    • blurry vision

    • toothache

    • acne

    • joint or muscle pain

    • anxiety

    • weight loss

  • Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, stop taking teriflunomide and call your doctor immediately or get emergency medical treatment:

    • fast, irregular, or slow heartbeat

    • headache

    • dizziness

    • pale skin

    • confusion

    • fever, cough, sore throat, chills, and other signs of infection

    • numbness, burning, or tingling in the hands, arms, feet, or legs

    • loss of muscle tone

    • weakness or heaviness in legs

    • cold, gray skin

    • red, peeling, or blistering skin

    • rash

    • hives

    • itching

    • difficulty swallowing

    • swelling of the face, eyes, mouth, throat, tongue, or lips

    • shortness of breath

    • rash that may occur with fever, swollen glands, or swelling of the face

    • stomach, side, or back pain

  • Teriflunomide may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Repaglinide Repaglinide The serum concentration of Repaglinide can be increased when it is combined with Teriflunomide.
Montelukast Montelukast The metabolism of Montelukast can be decreased when combined with Teriflunomide.
Leflunomide Leflunomide The risk or severity of adverse effects can be increased when Leflunomide is combined with Teriflunomide.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Teriflunomide.
Aminophylline Aminophylline The serum concentration of Aminophylline can be decreased when it is combined with Teriflunomide.
Anagrelide Anagrelide The serum concentration of Anagrelide can be decreased when it is combined with Teriflunomide.
Cilostazol Cilostazol The serum concentration of Cilostazol can be decreased when it is combined with Teriflunomide.
Clopidogrel Clopidogrel The serum concentration of Clopidogrel can be decreased when it is combined with Teriflunomide.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The excretion of Erythromycin can be decreased when combined with Teriflunomide.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The serum concentration of Conjugated estrogens can be decreased when it is combined with Teriflunomide.
Mycophenolate Mycophenolate The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Teriflunomide.
Paregoric Paregoric The metabolism of Morphine can be decreased when combined with Teriflunomide.
Prednisone Prednisone The risk or severity of adverse effects can be increased when Prednisone is combined with Teriflunomide.
Ranitidine Ranitidine The serum concentration of Ranitidine can be decreased when it is combined with Teriflunomide.
Sumatriptan Sumatriptan Teriflunomide may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus Tacrolimus may increase the immunosuppressive activities of Teriflunomide.
Tizanidine Tizanidine The serum concentration of Tizanidine can be decreased when it is combined with Teriflunomide.
Triamcinolone Triamcinolone The risk or severity of adverse effects can be increased when Triamcinolone is combined with Teriflunomide.
Zolmitriptan Zolmitriptan The serum concentration of Zolmitriptan can be decreased when it is combined with Teriflunomide.
Famotidine Injection Famotidine Injection The excretion of Famotidine can be decreased when combined with Teriflunomide.
Interferon Beta-1b Injection Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Teriflunomide.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Teriflunomide.
Methylprednisolone Injection Methylprednisolone Injection The risk or severity of adverse effects can be increased when Methylprednisolone is combined with Teriflunomide.
Metoclopramide Injection Metoclopramide Injection The serum concentration of Metoclopramide can be decreased when it is combined with Teriflunomide.
Morphine Injection Morphine Injection The metabolism of Morphine can be decreased when combined with Teriflunomide.
Zidovudine Injection Zidovudine Injection The risk or severity of adverse effects can be increased when Zidovudine is combined with Teriflunomide.
Cyclosporine Cyclosporine Teriflunomide may increase the immunosuppressive activities of Cyclosporine.
Torsemide Torsemide The metabolism of Torasemide can be decreased when combined with Teriflunomide.
Olanzapine Olanzapine The serum concentration of Olanzapine can be decreased when it is combined with Teriflunomide.
Alosetron Alosetron The serum concentration of Alosetron can be decreased when it is combined with Teriflunomide.
Hydroxychloroquine Hydroxychloroquine The risk or severity of adverse effects can be increased when Hydroxychloroquine is combined with Teriflunomide.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Sevelamer Sevelamer Sevelamer may increase the excretion rate of Teriflunomide which could result in a lower serum level and potentially a reduction in efficacy.
Telmisartan Telmisartan Telmisartan may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Temozolomide Temozolomide The risk or severity of adverse effects can be increased when Temozolomide is combined with Teriflunomide.
Anakinra Anakinra The risk or severity of adverse effects can be increased when Anakinra is combined with Teriflunomide.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Teriflunomide.
Etanercept Injection Etanercept Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Teriflunomide.
Tenofovir Tenofovir The excretion of Tenofovir can be decreased when combined with Teriflunomide.
Sirolimus Sirolimus The risk or severity of adverse effects can be increased when Sirolimus is combined with Teriflunomide.
Epirubicin Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with Teriflunomide.
Adalimumab Injection Adalimumab Injection The risk or severity of adverse effects can be increased when Adalimumab is combined with Teriflunomide.
Ezetimibe Ezetimibe Ezetimibe may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Glatiramer Injection Glatiramer Injection The risk or severity of adverse effects can be increased when Glatiramer is combined with Teriflunomide.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Teriflunomide.
Rosuvastatin Rosuvastatin The serum concentration of Rosuvastatin can be increased when it is combined with Teriflunomide.
Tegaserod Tegaserod Teriflunomide may decrease the excretion rate of Tegaserod which could result in a higher serum level.
Frovatriptan Frovatriptan The serum concentration of Frovatriptan can be decreased when it is combined with Teriflunomide.
Progesterone Progesterone Progesterone may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Teriflunomide.
Infliximab Injection Infliximab Injection The risk or severity of adverse effects can be increased when Infliximab is combined with Teriflunomide.
Duloxetine Duloxetine The serum concentration of Duloxetine can be decreased when it is combined with Teriflunomide.
Bosentan Bosentan The excretion of Bosentan can be decreased when combined with Teriflunomide.
Cefditoren Cefditoren The excretion of Cefdinir can be decreased when combined with Teriflunomide.
Cinacalcet Cinacalcet The serum concentration of Cinacalcet can be decreased when it is combined with Teriflunomide.
Natalizumab Injection Natalizumab Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Natalizumab.
Erlotinib Erlotinib The serum concentration of Erlotinib can be decreased when it is combined with Teriflunomide.
Eszopiclone Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Teriflunomide.
Entecavir Entecavir The serum concentration of Entecavir can be decreased when it is combined with Teriflunomide.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Teriflunomide.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Teriflunomide.
Ramelteon Ramelteon The serum concentration of Ramelteon can be decreased when it is combined with Teriflunomide.
Abatacept Injection Abatacept Injection The risk or severity of adverse effects can be increased when Abatacept is combined with Teriflunomide.
Rasagiline Rasagiline The serum concentration of Rasagiline can be decreased when it is combined with Teriflunomide.
Imatinib Imatinib The serum concentration of Imatinib can be decreased when it is combined with Teriflunomide.
Sitagliptin Sitagliptin The metabolism of Sitagliptin can be decreased when combined with Teriflunomide.
Bevacizumab Injection Bevacizumab Injection The risk or severity of adverse effects can be increased when Bevacizumab is combined with Teriflunomide.
Gefitinib Gefitinib Gefitinib may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Bortezomib Bortezomib The serum concentration of Bortezomib can be decreased when it is combined with Teriflunomide.
Clofarabine Injection Clofarabine Injection The risk or severity of adverse effects can be increased when Clofarabine is combined with Teriflunomide.
Hepatitis B Vaccine Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Teriflunomide.
Influenza Vaccine, Inactivated or Recombinant Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Teriflunomide.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Teriflunomide.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Teriflunomide.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Teriflunomide.
Primaquine Primaquine The serum concentration of Primaquine can be decreased when it is combined with Teriflunomide.
Rituximab Injection Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Teriflunomide.
Pemetrexed Injection Pemetrexed Injection The serum concentration of Pemetrexed can be decreased when it is combined with Teriflunomide.
Vorinostat Vorinostat The risk or severity of adverse effects can be increased when Vorinostat is combined with Teriflunomide.
Sorafenib Sorafenib The serum concentration of Sorafenib can be decreased when it is combined with Teriflunomide.
Sunitinib Sunitinib The risk or severity of adverse effects can be increased when Sunitinib is combined with Teriflunomide.
Dronabinol Dronabinol Dronabinol may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Lapatinib Lapatinib The metabolism of Lapatinib can be decreased when combined with Teriflunomide.
Dasatinib Dasatinib The serum concentration of Dasatinib can be decreased when it is combined with Teriflunomide.
Mexiletine Mexiletine The serum concentration of Mexiletine can be decreased when it is combined with Teriflunomide.
Azacitidine Injection Azacitidine Injection The risk or severity of adverse effects can be increased when Azacitidine is combined with Teriflunomide.
Ivermectin Ivermectin Teriflunomide may decrease the excretion rate of Ivermectin which could result in a higher serum level.
Temsirolimus Temsirolimus The risk or severity of adverse effects can be increased when Temsirolimus is combined with Teriflunomide.
Nelarabine Injection Nelarabine Injection The risk or severity of adverse effects can be increased when Nelarabine is combined with Teriflunomide.
Lenalidomide Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with Teriflunomide.
Nilotinib Nilotinib The risk or severity of adverse effects can be increased when Nilotinib is combined with Teriflunomide.
Bexarotene Bexarotene The risk or severity of adverse effects can be increased when Bexarotene is combined with Teriflunomide.
Budesonide Budesonide The risk or severity of adverse effects can be increased when Budesonide is combined with Teriflunomide.
Chloramphenicol Injection Chloramphenicol Injection The risk or severity of adverse effects can be increased when Chloramphenicol is combined with Teriflunomide.
Decitabine Injection Decitabine Injection The risk or severity of adverse effects can be increased when Decitabine is combined with Teriflunomide.
Doripenem Injection Doripenem Injection The excretion of Doripenem can be decreased when combined with Teriflunomide.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Arsenic trioxide is combined with Teriflunomide.
Mitoxantrone Injection Mitoxantrone Injection The risk or severity of adverse effects can be increased when Mitoxantrone is combined with Teriflunomide.
Tretinoin Tretinoin The risk or severity of adverse effects can be increased when Tretinoin is combined with Teriflunomide.
Bendamustine Injection Bendamustine Injection The serum concentration of Bendamustine can be decreased when it is combined with Teriflunomide.
Leucovorin Injection Leucovorin Injection The excretion of Leucovorin can be decreased when combined with Teriflunomide.
Flecainide Flecainide The serum concentration of Flecainide can be decreased when it is combined with Teriflunomide.
Certolizumab Injection Certolizumab Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The risk or severity of adverse effects can be increased when Ixabepilone is combined with Teriflunomide.
Irinotecan Injection Irinotecan Injection The risk or severity of adverse effects can be increased when Irinotecan is combined with Teriflunomide.
Estramustine Estramustine The risk or severity of adverse effects can be increased when Estramustine is combined with Teriflunomide.
Praziquantel Praziquantel The serum concentration of Praziquantel can be decreased when it is combined with Teriflunomide.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Teriflunomide.
Dexrazoxane Injection Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Teriflunomide.
Eltrombopag Eltrombopag The serum concentration of Eltrombopag can be decreased when it is combined with Teriflunomide.
Ibritumomab Injection Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Teriflunomide.
Betaxolol Betaxolol The serum concentration of Betaxolol can be decreased when it is combined with Teriflunomide.
Everolimus Everolimus The risk or severity of adverse effects can be increased when Everolimus is combined with Teriflunomide.
Pralatrexate Injection Pralatrexate Injection The risk or severity of adverse effects can be increased when Pralatrexate is combined with Teriflunomide.
Saxagliptin Saxagliptin The excretion of Saxagliptin can be decreased when combined with Teriflunomide.
Topotecan Topotecan The risk or severity of adverse effects can be increased when Topotecan is combined with Teriflunomide.
Golimumab Injection Golimumab Injection The risk or severity of adverse effects can be increased when Golimumab is combined with Teriflunomide.
Pazopanib Pazopanib The serum concentration of Pazopanib can be decreased when it is combined with Teriflunomide.
Asenapine Asenapine The serum concentration of Asenapine can be decreased when it is combined with Teriflunomide.
Pitavastatin Pitavastatin Teriflunomide may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Albendazole Albendazole The serum concentration of Albendazole can be decreased when it is combined with Teriflunomide.
Denosumab Injection Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Teriflunomide.
Tocilizumab Injection Tocilizumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Teriflunomide.
Fingolimod Fingolimod Teriflunomide may increase the immunosuppressive activities of Fingolimod.
Eribulin Injection Eribulin Injection The risk or severity of adverse effects can be increased when Eribulin is combined with Teriflunomide.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Teriflunomide can be decreased when combined with Cabazitaxel.
Acetaminophen Injection Acetaminophen Injection The serum concentration of Acetaminophen can be decreased when it is combined with Teriflunomide.
Denileukin Diftitox Injection Denileukin Diftitox Injection The risk or severity of adverse effects can be increased when Aldesleukin is combined with Teriflunomide.
Sipuleucel-T Injection Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Teriflunomide.
Belimumab Injection Belimumab Injection The risk or severity of adverse effects can be increased when Belimumab is combined with Teriflunomide.
Busulfan Injection Busulfan Injection The risk or severity of adverse effects can be increased when Busulfan is combined with Teriflunomide.
Roflumilast Roflumilast Roflumilast may increase the immunosuppressive activities of Teriflunomide.
Rilpivirine Rilpivirine Rilpivirine may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Telaprevir Telaprevir Teriflunomide may decrease the excretion rate of Glecaprevir which could result in a higher serum level.
Cyclophosphamide Injection Cyclophosphamide Injection The risk or severity of adverse effects can be increased when Cyclophosphamide is combined with Teriflunomide.
Rivaroxaban Rivaroxaban Teriflunomide may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The risk or severity of adverse effects can be increased when Brentuximab vedotin is combined with Teriflunomide.
Ruxolitinib Ruxolitinib The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Teriflunomide.
Vandetanib Vandetanib Vandetanib may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Vemurafenib Vemurafenib Teriflunomide may decrease the excretion rate of Vemurafenib which could result in a higher serum level.
Vismodegib Vismodegib Vismodegib may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Belatacept Injection Belatacept Injection The risk or severity of adverse effects can be increased when Belatacept is combined with Teriflunomide.
Basiliximab Injection Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Teriflunomide.
Axitinib Axitinib The serum concentration of Axitinib can be decreased when it is combined with Teriflunomide.
Melphalan Injection Melphalan Injection The risk or severity of adverse effects can be increased when Melphalan is combined with Teriflunomide.
Ambrisentan Ambrisentan The excretion of Ambrisentan can be decreased when combined with Teriflunomide.
Eculizumab Injection Eculizumab Injection The risk or severity of adverse effects can be increased when Eculizumab is combined with Teriflunomide.
Carfilzomib Injection Carfilzomib Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Carfilzomib.
Enzalutamide Enzalutamide The metabolism of Enzalutamide can be decreased when combined with Teriflunomide.
Regorafenib Regorafenib Regorafenib may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Bosutinib Bosutinib The risk or severity of adverse effects can be increased when Bosutinib is combined with Teriflunomide.
Corticotropin, Repository Injection Corticotropin, Repository Injection The risk or severity of adverse effects can be increased when Corticotropin is combined with Teriflunomide.
Tofacitinib Tofacitinib Teriflunomide may increase the immunosuppressive activities of Tofacitinib.
Dimethyl Fumarate Dimethyl Fumarate The risk or severity of adverse effects can be increased when Teriflunomide is combined with Dimethyl fumarate.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Teriflunomide.
Pomalidomide Pomalidomide The serum concentration of Pomalidomide can be decreased when it is combined with Teriflunomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The risk or severity of adverse effects can be increased when Trastuzumab emtansine is combined with Teriflunomide.
Apixaban Apixaban Teriflunomide may decrease the excretion rate of Apixaban which could result in a higher serum level.
Dabrafenib Dabrafenib The metabolism of Dabrafenib can be decreased when combined with Teriflunomide.
Dolutegravir Dolutegravir Teriflunomide may decrease the excretion rate of Dolutegravir which could result in a higher serum level.
Afatinib Afatinib Teriflunomide may decrease the excretion rate of Afatinib which could result in a higher serum level.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Teriflunomide.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Teriflunomide.
Perampanel Perampanel The serum concentration of Perampanel can be decreased when it is combined with Teriflunomide.
Ibrutinib Ibrutinib The risk or severity of adverse effects can be increased when Teriflunomide is combined with Ibrutinib.
Ketorolac Injection Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Teriflunomide.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Obinutuzumab.
Simeprevir Simeprevir Simeprevir may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Sofosbuvir Sofosbuvir Teriflunomide may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin The serum concentration of Dapagliflozin can be decreased when it is combined with Teriflunomide.
Apremilast Apremilast The serum concentration of Apremilast can be decreased when it is combined with Teriflunomide.
Siltuximab Injection Siltuximab Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Siltuximab.
Vedolizumab Injection Vedolizumab Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Vedolizumab.
Belinostat Injection Belinostat Injection The risk or severity of adverse effects can be increased when Belinostat is combined with Teriflunomide.
Idelalisib Idelalisib The risk or severity of adverse effects can be increased when Teriflunomide is combined with Idelalisib.
Testosterone Injection Testosterone Injection Teriflunomide may decrease the excretion rate of Testosterone which could result in a higher serum level.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Peginterferon beta-1a.
Olaparib Olaparib The risk or severity of adverse effects can be increased when Teriflunomide is combined with Olaparib.
Blinatumomab Injection Blinatumomab Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Blinatumomab.
Caspofungin Injection Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Teriflunomide.
Tasimelteon Tasimelteon The serum concentration of Tasimelteon can be decreased when it is combined with Teriflunomide.
Riociguat Riociguat Teriflunomide may decrease the excretion rate of Riociguat which could result in a higher serum level.
Pirfenidone Pirfenidone The serum concentration of Pirfenidone can be decreased when it is combined with Teriflunomide.
Secukinumab Injection Secukinumab Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Secukinumab.
Palbociclib Palbociclib The risk or severity of adverse effects can be increased when Teriflunomide is combined with Palbociclib.
Lenvatinib Lenvatinib Teriflunomide may decrease the excretion rate of Lenvatinib which could result in a higher serum level.
Panobinostat Panobinostat The risk or severity of adverse effects can be increased when Panobinostat is combined with Teriflunomide.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The serum concentration of Haloperidol can be decreased when it is combined with Teriflunomide.
Rolapitant Rolapitant Rolapitant may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Prednisolone Prednisolone The risk or severity of adverse effects can be increased when Prednisolone is combined with Teriflunomide.
Daclatasvir Daclatasvir Daclatasvir may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Eluxadoline Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Teriflunomide.
Cobimetinib Cobimetinib The excretion of Cobimetinib can be decreased when combined with Teriflunomide.
Mepolizumab Injection Mepolizumab Injection The risk or severity of adverse effects can be increased when Mepolizumab is combined with Teriflunomide.
Trabectedin Injection Trabectedin Injection The risk or severity of adverse effects can be increased when Trabectedin is combined with Teriflunomide.
Osimertinib Osimertinib Teriflunomide may decrease the excretion rate of Osimertinib which could result in a higher serum level.
Alectinib Alectinib Alectinib may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Dexamethasone Injection Dexamethasone Injection The risk or severity of adverse effects can be increased when Dexamethasone is combined with Teriflunomide.
Ixekizumab Injection Ixekizumab Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Ixekizumab.
Venetoclax Venetoclax Teriflunomide may decrease the excretion rate of Venetoclax which could result in a higher serum level.
Cobicistat Cobicistat Cobicistat may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Selexipag Selexipag The metabolism of Selexipag can be decreased when combined with Teriflunomide.
Rucaparib Rucaparib The serum concentration of Rucaparib can be decreased when it is combined with Teriflunomide.
Brodalumab Injection Brodalumab Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Brodalumab.
Brigatinib Brigatinib The metabolism of Brigatinib can be decreased when combined with Teriflunomide.
Doxepin (Insomnia) Doxepin (Insomnia) The serum concentration of Doxepin can be decreased when it is combined with Teriflunomide.
Deflazacort Deflazacort The risk or severity of adverse effects can be increased when Teriflunomide is combined with Deflazacort.
Safinamide Safinamide Safinamide may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Ocrelizumab Injection Ocrelizumab Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Ocrelizumab.
Edaravone Injection Edaravone Injection The excretion of Edaravone can be decreased when combined with Teriflunomide.
Sarilumab Injection Sarilumab Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Sarilumab.
Guselkumab Injection Guselkumab Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Guselkumab.
Enasidenib Enasidenib The serum concentration of Enasidenib can be decreased when it is combined with Teriflunomide.
Copanlisib Injection Copanlisib Injection Teriflunomide may decrease the excretion rate of Copanlisib which could result in a higher serum level.
Delafloxacin Delafloxacin Teriflunomide may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib Abemaciclib Teriflunomide may decrease the excretion rate of Abemaciclib which could result in a higher serum level.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Teriflunomide.
Letermovir Letermovir Letermovir may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Ertugliflozin Ertugliflozin Teriflunomide may decrease the excretion rate of Ertugliflozin which could result in a higher serum level.
Buprenorphine Injection Buprenorphine Injection Buprenorphine may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Apalutamide Apalutamide The metabolism of Apalutamide can be decreased when combined with Teriflunomide.
Penicillamine Penicillamine The risk or severity of adverse effects can be increased when Penicillamine is combined with Teriflunomide.
Fostamatinib Fostamatinib Fostamatinib may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Avatrombopag Avatrombopag Avatrombopag may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Baricitinib Baricitinib The risk or severity of adverse effects can be increased when Teriflunomide is combined with Baricitinib.
Lofexidine Lofexidine The serum concentration of Lofexidine can be decreased when it is combined with Teriflunomide.
Binimetinib Binimetinib The serum concentration of Binimetinib can be decreased when it is combined with Teriflunomide.
Lusutrombopag Lusutrombopag Teriflunomide may decrease the excretion rate of Lusutrombopag which could result in a higher serum level.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Teriflunomide.
Cannabidiol Cannabidiol Cannabidiol may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Dacomitinib Dacomitinib Teriflunomide may decrease the excretion rate of Dacomitinib which could result in a higher serum level.
Duvelisib Duvelisib Teriflunomide may decrease the excretion rate of Duvelisib which could result in a higher serum level.
Stiripentol Stiripentol The serum concentration of Stiripentol can be decreased when it is combined with Teriflunomide.
Talazoparib Talazoparib Teriflunomide may decrease the excretion rate of Talazoparib which could result in a higher serum level.
Gilteritinib Gilteritinib Gilteritinib may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Glasdegib Glasdegib The metabolism of Glasdegib can be decreased when combined with Teriflunomide.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Teriflunomide.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Teriflunomide.
Ravulizumab-cwvz Injection Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Ravulizumab.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Emapalumab.
Siponimod Siponimod The risk or severity of adverse effects can be increased when Teriflunomide is combined with Siponimod.
Acyclovir Ophthalmic Acyclovir Ophthalmic The serum concentration of Acyclovir can be decreased when it is combined with Teriflunomide.
Risankizumab-rzaa Injection Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Teriflunomide is combined with Risankizumab.
Alpelisib Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Teriflunomide.
Cladribine Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Teriflunomide.
Darolutamide Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Teriflunomide.
Triclabendazole Triclabendazole The serum concentration of Triclabendazole can be decreased when it is combined with Teriflunomide.
Pexidartinib Pexidartinib Teriflunomide may increase the hepatotoxic activities of Pexidartinib.
Istradefylline Istradefylline The serum concentration of Istradefylline can be decreased when it is combined with Teriflunomide.
Fedratinib Fedratinib Fedratinib may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Phenytoin Injection Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Teriflunomide.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Teriflunomide.
Lasmiditan Lasmiditan The serum concentration of Teriflunomide can be increased when it is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Teriflunomide.
Tazemetostat Tazemetostat Teriflunomide may decrease the excretion rate of Tazemetostat which could result in a higher serum level.
Ozanimod Ozanimod Teriflunomide may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Selumetinib Selumetinib The serum concentration of Selumetinib can be decreased when it is combined with Teriflunomide.
Rimegepant Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Teriflunomide.
Tucatinib Tucatinib Teriflunomide may decrease the excretion rate of Tucatinib which could result in a higher serum level.
Remdesivir Injection Remdesivir Injection The excretion of Remdesivir can be decreased when combined with Teriflunomide.
Ripretinib Ripretinib Teriflunomide may decrease the excretion rate of Ripretinib which could result in a higher serum level.
Capmatinib Capmatinib The serum concentration of Teriflunomide can be increased when it is combined with Capmatinib.
Fostemsavir Fostemsavir Teriflunomide may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The excretion of Belantamab mafodotin can be decreased when combined with Teriflunomide.
Pralsetinib Pralsetinib Teriflunomide may decrease the excretion rate of Pralsetinib which could result in a higher serum level.
Theophylline Theophylline The serum concentration of Theophylline can be decreased when it is combined with Teriflunomide.
Indomethacin Indomethacin The risk or severity of adverse effects can be increased when Indomethacin is combined with Teriflunomide.
Naproxen Naproxen The serum concentration of Naproxen can be decreased when it is combined with Teriflunomide.
Hydroxyurea Hydroxyurea The risk or severity of adverse effects can be increased when Hydroxyurea is combined with Teriflunomide.
Floxuridine Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Teriflunomide.
Methotrexate Injection Methotrexate Injection The risk or severity of adverse effects can be increased when Methotrexate is combined with Teriflunomide.
Chlorpromazine Chlorpromazine The serum concentration of Chlorpromazine can be decreased when it is combined with Teriflunomide.
Carmustine Carmustine The serum concentration of Carmustine can be decreased when it is combined with Teriflunomide.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Teriflunomide.
Tetracycline Tetracycline The excretion of Tetracycline can be decreased when combined with Teriflunomide.
Thioguanine Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Teriflunomide.
Trifluoperazine Trifluoperazine The serum concentration of Trifluoperazine can be decreased when it is combined with Teriflunomide.
Bleomycin Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Teriflunomide.
Dapsone Dapsone The metabolism of Dapsone can be decreased when combined with Teriflunomide.
Sulfadiazine Sulfadiazine The metabolism of Sulfadiazine can be decreased when combined with Teriflunomide.
Methadone Methadone The metabolism of Methadone can be decreased when combined with Teriflunomide.
Colestipol Colestipol Colestipol may increase the excretion rate of Teriflunomide which could result in a lower serum level and potentially a reduction in efficacy.
Maprotiline Maprotiline The serum concentration of Maprotiline can be decreased when it is combined with Teriflunomide.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Teriflunomide.
Perphenazine Perphenazine The serum concentration of Perphenazine can be decreased when it is combined with Teriflunomide.
Azathioprine Azathioprine The serum concentration of Azathioprine can be decreased when it is combined with Teriflunomide.
Sulfasalazine Sulfasalazine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Teriflunomide.
Hydrocortisone Hydrocortisone The excretion of Hydrocortisone can be decreased when combined with Teriflunomide.
Lomustine Lomustine The risk or severity of adverse effects can be increased when Lomustine is combined with Teriflunomide.
Doxorubicin Doxorubicin The risk or severity of adverse effects can be increased when Doxorubicin is combined with Teriflunomide.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Cytarabine is combined with Teriflunomide.
Mechlorethamine Mechlorethamine The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Teriflunomide.
Dactinomycin Dactinomycin The risk or severity of adverse effects can be increased when Dactinomycin is combined with Teriflunomide.
Carbamazepine Carbamazepine The risk or severity of adverse effects can be increased when Carbamazepine is combined with Teriflunomide.
Clonidine Clonidine The serum concentration of Clonidine can be decreased when it is combined with Teriflunomide.
Prazosin Prazosin Teriflunomide may decrease the excretion rate of Prazosin which could result in a higher serum level.
Cimetidine Cimetidine The excretion of Cimetidine can be decreased when combined with Teriflunomide.
Warfarin Warfarin The serum concentration of Warfarin can be decreased when it is combined with Teriflunomide.
Loperamide Loperamide The metabolism of Loperamide can be decreased when combined with Teriflunomide.
Daunorubicin Daunorubicin The risk or severity of adverse effects can be increased when Daunorubicin is combined with Teriflunomide.
Nitrofurantoin Nitrofurantoin Teriflunomide may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Digoxin Digoxin The excretion of Digoxin can be decreased when combined with Teriflunomide.
Chloroquine Chloroquine The metabolism of Chloroquine can be decreased when combined with Teriflunomide.
Quinine Quinine The serum concentration of Quinine can be decreased when it is combined with Teriflunomide.
Triamterene Triamterene The serum concentration of Triamterene can be decreased when it is combined with Teriflunomide.
Amitriptyline Amitriptyline The serum concentration of Amitriptyline can be decreased when it is combined with Teriflunomide.
Imipramine Imipramine The serum concentration of Imipramine can be decreased when it is combined with Teriflunomide.
Disopyramide Disopyramide The serum concentration of Disopyramide can be decreased when it is combined with Teriflunomide.
Valproic Acid Valproic Acid The excretion of Valproic acid can be decreased when combined with Teriflunomide.
Tamoxifen Tamoxifen The serum concentration of Tamoxifen can be decreased when it is combined with Teriflunomide.
Mitomycin Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with Teriflunomide.
Liothyronine Liothyronine The excretion of Liothyronine can be decreased when combined with Teriflunomide.
Methimazole Methimazole The risk or severity of adverse effects can be increased when Methimazole is combined with Teriflunomide.
Propylthiouracil Propylthiouracil The risk or severity of adverse effects can be increased when Propylthiouracil is combined with Teriflunomide.
Tolbutamide Tolbutamide The serum concentration of Tolbutamide can be increased when it is combined with Teriflunomide.
Dinoprostone Dinoprostone The excretion of Dinoprostone can be decreased when combined with Teriflunomide.
Cyclobenzaprine Cyclobenzaprine The serum concentration of Cyclobenzaprine can be decreased when it is combined with Teriflunomide.
Hydrochlorothiazide Hydrochlorothiazide The excretion of Hydrochlorothiazide can be decreased when combined with Teriflunomide.
Chlorzoxazone Chlorzoxazone The serum concentration of Chlorzoxazone can be decreased when it is combined with Teriflunomide.
Folic Acid Folic Acid Teriflunomide may decrease the excretion rate of Folic acid which could result in a higher serum level.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The serum concentration of Propranolol can be decreased when it is combined with Teriflunomide.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Mercaptopurine is combined with Teriflunomide.
Cholestyramine Resin Cholestyramine Resin Cholestyramine may increase the excretion rate of Teriflunomide which could result in a lower serum level and potentially a reduction in efficacy.
Allopurinol Allopurinol Teriflunomide may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Fluorouracil Injection Fluorouracil Injection The serum concentration of Fluorouracil can be decreased when it is combined with Teriflunomide.
Colchicine Colchicine The risk or severity of adverse effects can be increased when Colchicine is combined with Teriflunomide.
Cefaclor Cefaclor The excretion of Cefaclor can be decreased when combined with Teriflunomide.
Cefazolin Injection Cefazolin Injection The excretion of Cefazolin can be decreased when combined with Teriflunomide.
Cephalexin Cephalexin The excretion of Cephalexin can be decreased when combined with Teriflunomide.
Dacarbazine Dacarbazine The serum concentration of Dacarbazine can be decreased when it is combined with Teriflunomide.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Teriflunomide.
Thiotepa Injection Thiotepa Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Teriflunomide.
Vincristine Injection Vincristine Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Teriflunomide.
Captopril Captopril The excretion of Captopril can be decreased when combined with Teriflunomide.
Vinblastine Vinblastine The risk or severity of adverse effects can be increased when Vinblastine is combined with Teriflunomide.
Thiothixene Thiothixene The serum concentration of Thiothixene can be decreased when it is combined with Teriflunomide.
Chlorambucil Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Teriflunomide.
Diltiazem Diltiazem The metabolism of Diltiazem can be decreased when combined with Teriflunomide.
Nifedipine Nifedipine The serum concentration of Nifedipine can be decreased when it is combined with Teriflunomide.
Verapamil Verapamil The serum concentration of Verapamil can be decreased when it is combined with Teriflunomide.
Cisplatin Injection Cisplatin Injection The risk or severity of adverse effects can be increased when Cisplatin is combined with Teriflunomide.
Piroxicam Piroxicam The metabolism of Piroxicam can be decreased when combined with Teriflunomide.
Bumetanide Bumetanide The excretion of Bumetanide can be decreased when combined with Teriflunomide.
Streptozocin Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with Teriflunomide.
Etoposide Etoposide The serum concentration of Etoposide can be decreased when it is combined with Teriflunomide.
Glyburide Glyburide Teriflunomide may decrease the excretion rate of Glyburide which could result in a higher serum level.
Pentoxifylline Pentoxifylline The serum concentration of Pentoxifylline can be decreased when it is combined with Teriflunomide.
Guanabenz Guanabenz The serum concentration of Guanabenz can be decreased when it is combined with Teriflunomide.
Pimozide Pimozide The serum concentration of Pimozide can be decreased when it is combined with Teriflunomide.
Enalapril Enalapril The excretion of Enalapril can be decreased when combined with Teriflunomide.
Amiodarone Amiodarone The metabolism of Amiodarone can be decreased when combined with Teriflunomide.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Teriflunomide.
Diclofenac Diclofenac The serum concentration of Diclofenac can be decreased when it is combined with Teriflunomide.
Fluoxetine Fluoxetine The serum concentration of Fluoxetine can be decreased when it is combined with Teriflunomide.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Teriflunomide.
Clozapine Clozapine The serum concentration of Clozapine can be decreased when it is combined with Teriflunomide.
Idarubicin Idarubicin The risk or severity of adverse effects can be increased when Idarubicin is combined with Teriflunomide.
Fludarabine Injection Fludarabine Injection The risk or severity of adverse effects can be increased when Fludarabine is combined with Teriflunomide.
Pentostatin Injection Pentostatin Injection The risk or severity of adverse effects can be increased when Pentostatin is combined with Teriflunomide.
Nabumetone Nabumetone The serum concentration of Nabumetone can be decreased when it is combined with Teriflunomide.
Pravastatin Pravastatin Pravastatin may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Quinapril Quinapril The excretion of Quinapril can be decreased when combined with Teriflunomide.
Simvastatin Simvastatin The metabolism of Simvastatin can be decreased when combined with Teriflunomide.
Teniposide Injection Teniposide Injection The risk or severity of adverse effects can be increased when Teniposide is combined with Teriflunomide.
Zolpidem Zolpidem The serum concentration of Zolpidem can be decreased when it is combined with Teriflunomide.
Omeprazole Omeprazole Omeprazole may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Cisapride Cisapride The metabolism of Cisapride can be decreased when combined with Teriflunomide.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Teriflunomide.
Venlafaxine Venlafaxine Venlafaxine may increase the excretion rate of Teriflunomide which could result in a lower serum level and potentially a reduction in efficacy.
Fluvoxamine Fluvoxamine The serum concentration of Fluvoxamine can be decreased when it is combined with Teriflunomide.
Valacyclovir Valacyclovir The excretion of Valaciclovir can be decreased when combined with Teriflunomide.
Vinorelbine Injection Vinorelbine Injection The risk or severity of adverse effects can be increased when Vinorelbine is combined with Teriflunomide.
Carboplatin Injection Carboplatin Injection The risk or severity of adverse effects can be increased when Carboplatin is combined with Teriflunomide.
Lansoprazole Lansoprazole Lansoprazole may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Alprostadil Urogenital Alprostadil Urogenital The excretion of Alprostadil can be decreased when combined with Teriflunomide.
Ifosfamide Injection Ifosfamide Injection The risk or severity of adverse effects can be increased when Ifosfamide is combined with Teriflunomide.
Pegaspargase Injection Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Teriflunomide.
Nicardipine Nicardipine The metabolism of Nicardipine can be decreased when combined with Teriflunomide.
Saquinavir Saquinavir Saquinavir may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Lamivudine Lamivudine Teriflunomide may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole Riluzole The serum concentration of Riluzole can be decreased when it is combined with Teriflunomide.
Anastrozole Anastrozole The metabolism of Anastrozole can be decreased when combined with Teriflunomide.
Gemcitabine Injection Gemcitabine Injection The risk or severity of adverse effects can be increased when Gemcitabine is combined with Teriflunomide.
Ritonavir Ritonavir Ritonavir may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Docetaxel Injection Docetaxel Injection The risk or severity of adverse effects can be increased when Docetaxel is combined with Teriflunomide.
Clomipramine Clomipramine The serum concentration of Clomipramine can be decreased when it is combined with Teriflunomide.
Zafirlukast Zafirlukast The metabolism of Zafirlukast can be decreased when combined with Teriflunomide.
Mirtazapine Mirtazapine The serum concentration of Mirtazapine can be decreased when it is combined with Teriflunomide.
Zileuton Zileuton The serum concentration of Zileuton can be decreased when it is combined with Teriflunomide.
Valsartan Valsartan The excretion of Valsartan can be decreased when combined with Teriflunomide.
Donepezil Donepezil Teriflunomide may decrease the excretion rate of Donepezil which could result in a higher serum level.
Nelfinavir Nelfinavir Nelfinavir may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Fexofenadine Fexofenadine The excretion of Fexofenadine can be decreased when combined with Teriflunomide.
Carvedilol Carvedilol The serum concentration of Carvedilol can be decreased when it is combined with Teriflunomide.
Flutamide Flutamide The serum concentration of Flutamide can be decreased when it is combined with Teriflunomide.
Selegiline Selegiline The serum concentration of Selegiline can be decreased when it is combined with Teriflunomide.
Propafenone Propafenone The serum concentration of Propafenone can be decreased when it is combined with Teriflunomide.
Raloxifene Raloxifene Teriflunomide may decrease the excretion rate of Raloxifene which could result in a higher serum level.
Irbesartan Irbesartan The metabolism of Irbesartan can be decreased when combined with Teriflunomide.
Ropinirole Ropinirole The metabolism of Ropinirole can be increased when combined with Teriflunomide.
Paroxetine Paroxetine The serum concentration of Paroxetine can be decreased when it is combined with Teriflunomide.
Capecitabine Capecitabine The risk or severity of adverse effects can be increased when Capecitabine is combined with Teriflunomide.
Efavirenz Efavirenz The serum concentration of Efavirenz can be decreased when it is combined with Teriflunomide.
Pioglitazone Pioglitazone The metabolism of Pioglitazone can be decreased when combined with Teriflunomide.
Trastuzumab Injection Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Teriflunomide.
Celecoxib Celecoxib The metabolism of Celecoxib can be decreased when combined with Teriflunomide.
Rosiglitazone Rosiglitazone The metabolism of Rosiglitazone can be decreased when combined with Teriflunomide.
Thalidomide Thalidomide The risk or severity of adverse effects can be increased when Thalidomide is combined with Teriflunomide.
Oseltamivir Oseltamivir The excretion of Oseltamivir can be decreased when combined with Teriflunomide.
Colesevelam Colesevelam Colesevelam may increase the excretion rate of Teriflunomide which could result in a lower serum level and potentially a reduction in efficacy.
Rabeprazole Rabeprazole Rabeprazole may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Terbinafine Terbinafine The serum concentration of Terbinafine can be decreased when it is combined with Teriflunomide.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists