Tolterodine
Generic name: Pronounced as (tole ter' a deen)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 05/15/2019
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Drug interactions
Why is this medication prescribed?
Tolterodine is used treat overactive bladder (a condition in which the bladder muscles contract uncontrollably and cause frequent urination, urgent need to urinate, and inability to control urination). Tolterodine is in a class of medications called antimuscarinics. It works by relaxing the bladder muscles preventing bladder contraction.
How should this medicine be used?
Tolterodine comes as a tablet and an extended-release (long-acting) capsule to take by mouth. The tablet is usually taken twice a day. The extended-release capsule is usually taken once a day with liquids. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take tolterodine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the extended-release capsules whole; do not split, chew, or crush them.
Other uses for this medicine
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking tolterodine,
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tell your doctor and pharmacist if you are allergic to tolterodine, fesoterodine fumarate (Toviaz), any other medications, or any of the ingredients in tolterodine tablets or extended-release capsules. Ask your pharmacist for a list of the ingredients.
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tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amiodarone (Nexterone, Pacerone); antihistamines; atazanavir (Reyataz, in Evotaz); clarithromycin; cyclosporine (Gengraf, Neoral, Sandimmune); donepezil (Aricept, in Namzaric); erythromycin (E.E.S., Ery-Tab, others); galantamine (Razadyne); itraconazole (Onmel, Sporanox. Tolsura); medications for irritable bowel disease, motion sickness, or Parkinson's disease; ketoconazole; procainamide; quinidine (in Nuedexta); ritonavir (Norvir, in Kaletra, Technivie, Viekira); rivastigmine (Exelon); saquinavir (Invirase); sotalol (Betapace, Sorine, Sotylize); and vinblastine . Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
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tell your doctor if you have or have ever had glaucoma (increased pressure in the eye that may cause vision loss), urinary retention (inability to empty your bladder completely or at all), or gastric retention (slow emptying of your stomach).Your doctor may tell you not to take tolterodine.
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tell your doctor if you or anyone in your family has or has ever had a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death), or if you have or have ever had bladder problems, stomach or bowel problems including problems with constipation, myasthenia gravis (a disorder of the nervous system that causes muscle weakness), or kidney or liver disease..
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tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking tolterodine, call your doctor.
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you should know that tolterodine may make you dizzy or drowsy, or cause blurred vision or other vision problems. Do not drive a car or operate machinery until you know how this medication affects you.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Tolterodine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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dry mouth
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heartburn
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headache
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constipation
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diarrhea
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dry eyes
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dry skin
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joint pain
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abdominal pain
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excessive tiredness
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difficulty emptying the bladder
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painful urination
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weight gain
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anxiety
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Some side effects can be serious. If you experience any of the following symptoms stop taking tolterodine and call your doctor immediately or get emergency medical treatment:
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swelling of the face, throat, tongue, lips, and eyes
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difficulty swallowing or breathing
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom).
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include the following:
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confusion
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dry mouth
What OTHER INFORMATION should I know?
Keep all appointments with your doctor.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Moxifloxacin | Moxifloxacin The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Moxifloxacin. |
Montelukast | Montelukast The metabolism of Tolterodine can be decreased when combined with Montelukast. |
Leflunomide | Leflunomide The metabolism of Tolterodine can be decreased when combined with Leflunomide. |
Delavirdine | Delavirdine The serum concentration of Tolterodine can be increased when it is combined with Delavirdine. |
Nevirapine | Nevirapine The metabolism of Tolterodine can be decreased when combined with Nevirapine. |
Dolasetron | Dolasetron The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Dolasetron. |
Anagrelide | Anagrelide The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Anagrelide. |
Bisacodyl | Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Tolterodine. |
Candesartan | Candesartan The metabolism of Tolterodine can be decreased when combined with Candesartan. |
Cilostazol | Cilostazol The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Cilostazol. |
Clopidogrel | Clopidogrel The metabolism of Tolterodine can be decreased when combined with Clopidogrel. |
Diphenoxylate | Diphenoxylate The risk or severity of adverse effects can be increased when Diphenoxylate is combined with Tolterodine. |
Erythromycin and Sulfisoxazole | Erythromycin and Sulfisoxazole The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Erythromycin. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) Conjugated estrogens may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Fenofibrate | Fenofibrate The metabolism of Tolterodine can be decreased when combined with Fenofibrate. |
Guanfacine | Guanfacine Guanfacine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Magnesium Hydroxide | Magnesium Hydroxide Tolterodine may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level. |
Magnesium Oxide | Magnesium Oxide The therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Tolterodine. |
Mycophenolate | Mycophenolate Mycophenolic acid may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Naratriptan | Naratriptan Naratriptan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Olsalazine | Olsalazine Olsalazine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Paregoric | Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Tolterodine. |
Penbutolol | Penbutolol The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Acebutolol. |
Pentazocine | Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Tolterodine. |
Polyethylene glycol-electrolyte solution (PEG-ES) | Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Tolterodine. |
Potassium | Potassium Potassium may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Prednisone | Prednisone Prednisone may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Psyllium | Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Tolterodine. |
Ranitidine | Ranitidine The metabolism of Tolterodine can be decreased when combined with Ranitidine. |
Reserpine | Reserpine Reserpine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Rizatriptan | Rizatriptan Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Sumatriptan | Sumatriptan Sumatriptan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Tacrolimus | Tacrolimus Tacrolimus may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Tizanidine | Tizanidine Tizanidine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Zolmitriptan | Zolmitriptan Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Ampicillin Injection | Ampicillin Injection Ampicillin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Doxycycline Injection | Doxycycline Injection Doxycycline may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Famotidine Injection | Famotidine Injection The risk or severity of QTc prolongation can be increased when Famotidine is combined with Tolterodine. |
Fluconazole Injection | Fluconazole Injection The metabolism of Tolterodine can be decreased when combined with Fluconazole. |
Foscarnet Injection | Foscarnet Injection Foscarnet may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Hydromorphone Injection | Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Tolterodine. |
Levofloxacin Injection | Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Levofloxacin. |
Meperidine Injection | Meperidine Injection The risk or severity of adverse effects can be increased when Tolterodine is combined with Meperidine. |
Metoclopramide Injection | Metoclopramide Injection The therapeutic efficacy of Tolterodine can be decreased when used in combination with Metoclopramide. |
Metronidazole Injection | Metronidazole Injection The metabolism of Tolterodine can be decreased when combined with Metronidazole. |
Morphine Injection | Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Tolterodine. |
Pamidronate Injection | Pamidronate Injection Pamidronic acid may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Vancomycin Injection | Vancomycin Injection Tolterodine may decrease the excretion rate of Vancomycin which could result in a higher serum level. |
Zidovudine Injection | Zidovudine Injection The metabolism of Tolterodine can be decreased when combined with Zidovudine. |
Altretamine | Altretamine Amphetamine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Cefuroxime | Cefuroxime Cefuroxime may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Cyclosporine | Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Tolterodine. |
Ondansetron | Ondansetron The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Ondansetron. |
Granisetron | Granisetron The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Granisetron. |
Torsemide | Torsemide The metabolism of Tolterodine can be decreased when combined with Torasemide. |
Olanzapine | Olanzapine Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Alosetron | Alosetron Alosetron may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Dofetilide | Dofetilide The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Dofetilide. |
Entacapone | Entacapone Entacapone may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Hydroxychloroquine | Hydroxychloroquine The metabolism of Tolterodine can be decreased when combined with Hydroxychloroquine. |
Meloxicam | Meloxicam Meloxicam may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Oxcarbazepine | Oxcarbazepine Oxcarbazepine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Pantoprazole | Pantoprazole Pantoprazole may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Temozolomide | Temozolomide Temozolomide may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Zaleplon | Zaleplon Zaleplon may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Anakinra | Anakinra The metabolism of Tolterodine can be increased when combined with Anakinra. |
Desloratadine | Desloratadine Tolterodine may increase the central nervous system depressant (CNS depressant) activities of Desloratadine. |
Linezolid | Linezolid Linezolid may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Rivastigmine | Rivastigmine The therapeutic efficacy of Tolterodine can be decreased when used in combination with Rivastigmine. |
Trimipramine | Trimipramine The metabolism of Tolterodine can be decreased when combined with Trimipramine. |
Etanercept Injection | Etanercept Injection The metabolism of Tolterodine can be increased when combined with Etanercept. |
Glycopyrrolate | Glycopyrrolate The risk or severity of adverse effects can be increased when Tolterodine is combined with Glycopyrronium. |
Modafinil | Modafinil The metabolism of Tolterodine can be decreased when combined with Modafinil. |
Perindopril | Perindopril Perindopril may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Tenofovir | Tenofovir Tenofovir may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Choline Magnesium Trisalicylate | Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Epinephrine Injection | Epinephrine Injection The metabolism of Tolterodine can be decreased when combined with Epinephrine. |
Eplerenone | Eplerenone Eplerenone may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Escitalopram | Escitalopram The serum concentration of Escitalopram can be increased when it is combined with Tolterodine. |
Zonisamide | Zonisamide Zonisamide may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Adalimumab Injection | Adalimumab Injection The metabolism of Tolterodine can be increased when combined with Adalimumab. |
Aripiprazole | Aripiprazole Aripiprazole may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Atomoxetine | Atomoxetine Atomoxetine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Dexmethylphenidate | Dexmethylphenidate Dexmethylphenidate may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Atazanavir | Atazanavir The serum concentration of Tolterodine can be increased when it is combined with Atazanavir. |
Almotriptan | Almotriptan Almotriptan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Eletriptan | Eletriptan Eletriptan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Mefloquine | Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Tolterodine. |
Polyethylene Glycol 3350 | Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Tolterodine. |
Rosuvastatin | Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Tolterodine. |
Vardenafil | Vardenafil The risk or severity of QTc prolongation can be increased when Vardenafil is combined with Tolterodine. |
Alfuzosin | Alfuzosin The risk or severity of QTc prolongation can be increased when Alfuzosin is combined with Tolterodine. |
Aprepitant | Aprepitant The metabolism of Tolterodine can be decreased when combined with Aprepitant. |
Emtricitabine | Emtricitabine Emtricitabine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Memantine | Memantine The therapeutic efficacy of Tolterodine can be decreased when used in combination with Memantine. |
Tegaserod | Tegaserod The metabolism of Tegaserod can be decreased when combined with Tolterodine. |
Tadalafil | Tadalafil Tadalafil may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Frovatriptan | Frovatriptan Frovatriptan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Gemifloxacin | Gemifloxacin The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Gemifloxacin. |
Progesterone | Progesterone The metabolism of Tolterodine can be decreased when combined with Progesterone. |
Apomorphine Injection | Apomorphine Injection Apomorphine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Infliximab Injection | Infliximab Injection The metabolism of Tolterodine can be increased when combined with Infliximab. |
Oxandrolone | Oxandrolone The metabolism of Tolterodine can be decreased when combined with Oxandrolone. |
Protriptyline | Protriptyline Protriptyline may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Duloxetine | Duloxetine The metabolism of Tolterodine can be decreased when combined with Duloxetine. |
Tinidazole | Tinidazole Tinidazole may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Trospium | Trospium The risk or severity of adverse effects can be increased when Trospium is combined with Tolterodine. |
Bosentan | Bosentan The metabolism of Tolterodine can be increased when combined with Bosentan. |
Cefditoren | Cefditoren Cefdinir may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Cinacalcet | Cinacalcet The metabolism of Tolterodine can be decreased when combined with Cinacalcet. |
Cyanocobalamin Injection | Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Erlotinib | Erlotinib The metabolism of Erlotinib can be decreased when combined with Tolterodine. |
Eszopiclone | Eszopiclone Eszopiclone may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Ganciclovir | Ganciclovir Ganciclovir may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Ribavirin | Ribavirin Ribavirin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Solifenacin | Solifenacin The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Solifenacin. |
Valganciclovir | Valganciclovir Tolterodine may decrease the excretion rate of Valganciclovir which could result in a higher serum level. |
Voriconazole | Voriconazole The serum concentration of Tolterodine can be increased when it is combined with Voriconazole. |
Adefovir | Adefovir Adefovir may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Dextroamphetamine | Dextroamphetamine Amphetamine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Peginterferon Alfa-2b (PEG-Intron) | Peginterferon Alfa-2b (PEG-Intron) The metabolism of Tolterodine can be increased when combined with Peginterferon alfa-2b. |
Pramlintide Injection | Pramlintide Injection The risk or severity of reduced gastrointestinal motility can be increased when Pramlintide is combined with Tolterodine. |
Sodium Oxybate | Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Ibandronate | Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Tolterodine. |
Isocarboxazid | Isocarboxazid Isocarboxazid may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Ramelteon | Ramelteon Ramelteon may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Darifenacin | Darifenacin The metabolism of Darifenacin can be decreased when combined with Tolterodine. |
Fentanyl | Fentanyl The risk or severity of adverse effects can be increased when Tolterodine is combined with Fentanyl. |
Pregabalin | Pregabalin Pregabalin may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Phenylephrine | Phenylephrine The risk or severity of Tachycardia can be increased when Phenylephrine is combined with Tolterodine. |
Tipranavir | Tipranavir The serum concentration of Tipranavir can be increased when it is combined with Tolterodine. |
Felbamate | Felbamate The metabolism of Tolterodine can be decreased when combined with Felbamate. |
Ranolazine | Ranolazine The serum concentration of Tolterodine can be increased when it is combined with Ranolazine. |
Abatacept Injection | Abatacept Injection The metabolism of Tolterodine can be increased when combined with Abatacept. |
Rasagiline | Rasagiline Tolterodine may increase the central nervous system depressant (CNS depressant) activities of Rasagiline. |
Imatinib | Imatinib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Imatinib. |
Sitagliptin | Sitagliptin Tolterodine may decrease the excretion rate of Sitagliptin which could result in a higher serum level. |
Varenicline | Varenicline Tolterodine may decrease the excretion rate of Varenicline which could result in a higher serum level. |
Gefitinib | Gefitinib The metabolism of Tolterodine can be decreased when combined with Gefitinib. |
Albuterol | Albuterol The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Tolterodine. |
Paliperidone | Paliperidone The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Paliperidone. |
Bortezomib | Bortezomib The risk or severity of QTc prolongation can be increased when Bortezomib is combined with Tolterodine. |
Clofarabine Injection | Clofarabine Injection Clofarabine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Lubiprostone | Lubiprostone Tolterodine may decrease the excretion rate of Lubiprostone which could result in a higher serum level. |
Oxaliplatin Injection | Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Oxaliplatin. |
Posaconazole | Posaconazole The serum concentration of Tolterodine can be increased when it is combined with Posaconazole. |
Primaquine | Primaquine The metabolism of Primaquine can be decreased when combined with Tolterodine. |
Darunavir | Darunavir The serum concentration of Darunavir can be increased when it is combined with Tolterodine. |
Pemetrexed Injection | Pemetrexed Injection Tolterodine may decrease the excretion rate of Pemetrexed which could result in a higher serum level. |
Dimenhydrinate | Dimenhydrinate The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Dimenhydrinate. |
Lisdexamfetamine | Lisdexamfetamine The risk or severity of Tachycardia can be increased when Tolterodine is combined with Lisdexamfetamine. |
Nabilone | Nabilone The risk or severity of Tachycardia and drowsiness can be increased when Tolterodine is combined with Nabilone. |
Vorinostat | Vorinostat The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Vorinostat. |
Sorafenib | Sorafenib The metabolism of Tolterodine can be decreased when combined with Sorafenib. |
Sunitinib | Sunitinib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Sunitinib. |
Dronabinol | Dronabinol The risk or severity of Tachycardia and drowsiness can be increased when Tolterodine is combined with Dronabinol. |
Lapatinib | Lapatinib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Lapatinib. |
Levocetirizine | Levocetirizine Levocetirizine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Pegaptanib Injection | Pegaptanib Injection Tolterodine may decrease the excretion rate of Pegaptanib which could result in a higher serum level. |
Dasatinib | Dasatinib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Dasatinib. |
Mexiletine | Mexiletine The metabolism of Tolterodine can be decreased when combined with Mexiletine. |
Armodafinil | Armodafinil The metabolism of Tolterodine can be decreased when combined with Armodafinil. |
Azacitidine Injection | Azacitidine Injection Azacitidine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Paclitaxel (with polyoxyethylated castor oil) Injection | Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Tolterodine. |
Temsirolimus | Temsirolimus The metabolism of Tolterodine can be decreased when combined with Temsirolimus. |
Lenalidomide | Lenalidomide Lenalidomide may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Nilotinib | Nilotinib The serum concentration of Tolterodine can be increased when it is combined with Nilotinib. |
Toremifene | Toremifene The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Toremifene. |
Bexarotene | Bexarotene The metabolism of Tolterodine can be decreased when combined with Bexarotene. |
Budesonide | Budesonide Tolterodine may decrease the excretion rate of Budesonide which could result in a higher serum level. |
Desmopressin | Desmopressin Desmopressin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Betaine | Betaine The therapeutic efficacy of Tolterodine can be decreased when used in combination with Glycine betaine. |
OnabotulinumtoxinA Injection | OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Tolterodine is combined with Botulinum toxin type A. |
RimabotulinumtoxinB Injection | RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Tolterodine is combined with Botulinum Toxin Type B. |
Doripenem Injection | Doripenem Injection Tolterodine may decrease the excretion rate of Doripenem which could result in a higher serum level. |
Etravirine | Etravirine The metabolism of Tolterodine can be decreased when combined with Etravirine. |
Arsenic Trioxide Injection | Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Arsenic trioxide. |
Desvenlafaxine | Desvenlafaxine Tolterodine may increase the central nervous system depressant (CNS depressant) activities of Desvenlafaxine. |
Cevimeline | Cevimeline Cevimeline may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Nebivolol | Nebivolol The metabolism of Nebivolol can be decreased when combined with Tolterodine. |
Tretinoin | Tretinoin The metabolism of Tolterodine can be decreased when combined with Tretinoin. |
Flecainide | Flecainide The metabolism of Flecainide can be decreased when combined with Tolterodine. |
Certolizumab Injection | Certolizumab Injection The metabolism of Tolterodine can be increased when combined with Certolizumab pegol. |
Daptomycin Injection | Daptomycin Injection Daptomycin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Methylnaltrexone Injection | Methylnaltrexone Injection Tolterodine may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level. |
Rufinamide | Rufinamide Rufinamide may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Midazolam | Midazolam Midazolam may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Naltrexone Injection | Naltrexone Injection The risk or severity of adverse effects can be increased when Tolterodine is combined with Naltrexone. |
Dexrazoxane Injection | Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Milnacipran | Milnacipran Tolterodine may increase the central nervous system depressant (CNS depressant) activities of Milnacipran. |
Plerixafor Injection | Plerixafor Injection Tolterodine may decrease the excretion rate of Plerixafor which could result in a higher serum level. |
Sodium Phosphate | Sodium Phosphate The therapeutic efficacy of Sodium phosphate, monobasic can be decreased when used in combination with Tolterodine. |
Fesoterodine | Fesoterodine Tolterodine may decrease the excretion rate of Fesoterodine which could result in a higher serum level. |
Degarelix Injection | Degarelix Injection The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Degarelix. |
Betaxolol | Betaxolol The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Betaxolol. |
Iloperidone | Iloperidone The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Iloperidone. |
Prasugrel | Prasugrel Tolterodine may decrease the excretion rate of Prasugrel which could result in a higher serum level. |
Lacosamide | Lacosamide Lacosamide may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Everolimus | Everolimus The metabolism of Tolterodine can be decreased when combined with Everolimus. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) Tolvaptan may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Dronedarone | Dronedarone The metabolism of Dronedarone can be decreased when combined with Tolterodine. |
AbobotulinumtoxinA Injection | AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Tolterodine is combined with Botulinum toxin type A. |
Pralatrexate Injection | Pralatrexate Injection Tolterodine may decrease the excretion rate of Pralatrexate which could result in a higher serum level. |
Palonosetron Injection | Palonosetron Injection Palonosetron may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Saxagliptin | Saxagliptin Tolterodine may decrease the excretion rate of Saxagliptin which could result in a higher serum level. |
Telavancin Injection | Telavancin Injection The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Telavancin. |
Romidepsin Injection | Romidepsin Injection The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Romidepsin. |
Tapentadol | Tapentadol The risk or severity of adverse effects can be increased when Tapentadol is combined with Tolterodine. |
Topotecan | Topotecan Topotecan may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Golimumab Injection | Golimumab Injection The metabolism of Tolterodine can be increased when combined with Golimumab. |
Pazopanib | Pazopanib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Pazopanib. |
Asenapine | Asenapine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Asenapine. |
Vigabatrin | Vigabatrin Vigabatrin may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Pitavastatin | Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Tolterodine. |
Oxymorphone | Oxymorphone The risk or severity of adverse effects can be increased when Oxymorphone is combined with Tolterodine. |
Tocilizumab Injection | Tocilizumab Injection The metabolism of Tolterodine can be increased when combined with Tocilizumab. |
Dalfampridine | Dalfampridine Tolterodine may decrease the excretion rate of Dalfampridine which could result in a higher serum level. |
Eribulin Injection | Eribulin Injection The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Eribulin. |
IncobotulinumtoxinA Injection | IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Tolterodine is combined with Botulinum toxin type A. |
Ceftaroline Injection | Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Lurasidone | Lurasidone Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Acetaminophen Injection | Acetaminophen Injection Acetaminophen may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Vilazodone | Vilazodone The metabolism of Tolterodine can be decreased when combined with Vilazodone. |
Ipilimumab Injection | Ipilimumab Injection Tolterodine may decrease the excretion rate of Ipilimumab which could result in a higher serum level. |
Denileukin Diftitox Injection | Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Terbutaline Injection | Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Tolterodine. |
Roflumilast | Roflumilast Tolterodine may decrease the excretion rate of Roflumilast which could result in a higher serum level. |
Rilpivirine | Rilpivirine The metabolism of Tolterodine can be decreased when combined with Rilpivirine. |
Cyclophosphamide Injection | Cyclophosphamide Injection The metabolism of Tolterodine can be decreased when combined with Cyclophosphamide. |
Abiraterone | Abiraterone The metabolism of Tolterodine can be decreased when combined with Abiraterone. |
Triptorelin Injection | Triptorelin Injection The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Triptorelin. |
Rivaroxaban | Rivaroxaban Tolterodine may decrease the excretion rate of Rivaroxaban which could result in a higher serum level. |
Ticagrelor | Ticagrelor The metabolism of Tolterodine can be decreased when combined with Ticagrelor. |
Ruxolitinib | Ruxolitinib Tolterodine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level. |
Vandetanib | Vandetanib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Vandetanib. |
Clobazam | Clobazam The metabolism of Tolterodine can be decreased when combined with Clobazam. |
Vemurafenib | Vemurafenib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Vemurafenib. |
Vismodegib | Vismodegib The metabolism of Tolterodine can be decreased when combined with Vismodegib. |
Deferiprone | Deferiprone Tolterodine may decrease the excretion rate of Deferiprone which could result in a higher serum level. |
Crizotinib | Crizotinib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Crizotinib. |
Cabergoline | Cabergoline Cabergoline may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Naloxone Injection | Naloxone Injection The serum concentration of Tolterodine can be increased when it is combined with Naloxone. |
Fondaparinux Injection | Fondaparinux Injection Fondaparinux may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Ezogabine | Ezogabine Tiagabine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Enzalutamide | Enzalutamide The metabolism of Tolterodine can be increased when combined with Enzalutamide. |
Mirabegron | Mirabegron The risk or severity of urinary retention can be increased when Tolterodine is combined with Mirabegron. |
Regorafenib | Regorafenib The metabolism of Tolterodine can be decreased when combined with Regorafenib. |
Linaclotide | Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Tolterodine. |
Cabozantinib (thyroid cancer) | Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Tolterodine. |
Teduglutide Injection | Teduglutide Injection Tolterodine may decrease the excretion rate of Teduglutide which could result in a higher serum level. |
Bedaquiline | Bedaquiline The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Bedaquiline. |
Alogliptin | Alogliptin Tolterodine may decrease the excretion rate of Alogliptin which could result in a higher serum level. |
Ponatinib | Ponatinib The metabolism of Ponatinib can be decreased when combined with Tolterodine. |
Pomalidomide | Pomalidomide Pomalidomide may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Apixaban | Apixaban The metabolism of Apixaban can be decreased when combined with Tolterodine. |
Canagliflozin | Canagliflozin Tolterodine may increase the excretion rate of Canagliflozin which could result in a lower serum level and potentially a reduction in efficacy. |
Methazolamide | Methazolamide Methazolamide may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Dabrafenib | Dabrafenib The metabolism of Tolterodine can be increased when combined with Dabrafenib. |
Ospemifene | Ospemifene The metabolism of Ospemifene can be decreased when combined with Tolterodine. |
Trametinib | Trametinib Tolterodine may decrease the excretion rate of Trametinib which could result in a higher serum level. |
Levomilnacipran | Levomilnacipran Tolterodine may increase the central nervous system depressant (CNS depressant) activities of Levomilnacipran. |
Ertapenem Injection | Ertapenem Injection Ertapenem may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Vortioxetine | Vortioxetine Tolterodine may increase the central nervous system depressant (CNS depressant) activities of Vortioxetine. |
Perampanel | Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Ibrutinib | Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Tolterodine. |
Ketorolac Injection | Ketorolac Injection Ketorolac may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Sofosbuvir | Sofosbuvir Tolterodine may decrease the excretion rate of Sofosbuvir which could result in a higher serum level. |
Dapagliflozin | Dapagliflozin Tolterodine may increase the excretion rate of Dapagliflozin which could result in a lower serum level and potentially a reduction in efficacy. |
Apremilast | Apremilast The metabolism of Tolterodine can be increased when combined with Apremilast. |
Droxidopa | Droxidopa Tolterodine may decrease the excretion rate of Droxidopa which could result in a higher serum level. |
Ceritinib | Ceritinib The metabolism of Tolterodine can be decreased when combined with Ceritinib. |
Siltuximab Injection | Siltuximab Injection The metabolism of Tolterodine can be increased when combined with Siltuximab. |
Eslicarbazepine | Eslicarbazepine Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Testosterone Injection | Testosterone Injection Testosterone may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Oritavancin Injection | Oritavancin Injection The metabolism of Tolterodine can be decreased when combined with Oritavancin. |
Hydrocodone | Hydrocodone The risk or severity of adverse effects can be increased when Hydrocodone is combined with Tolterodine. |
Suvorexant | Suvorexant Suvorexant may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Edoxaban | Edoxaban Tolterodine may decrease the excretion rate of Edoxaban which could result in a higher serum level. |
Methamphetamine | Methamphetamine Tolterodine may increase the central nervous system depressant (CNS depressant) activities of Metamfetamine. |
Tasimelteon | Tasimelteon Tasimelteon may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Secukinumab Injection | Secukinumab Injection The metabolism of Tolterodine can be increased when combined with Secukinumab. |
Risperidone Injection | Risperidone Injection Risperidone may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Lenvatinib | Lenvatinib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Lenvatinib. |
Naloxegol | Naloxegol The metabolism of Tolterodine can be decreased when combined with Naloxegol. |
Panobinostat | Panobinostat The metabolism of Tolterodine can be decreased when combined with Panobinostat. |
Haloperidol Injection | Haloperidol Injection The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Haloperidol. |
Ivabradine | Ivabradine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Ivabradine. |
Amiloride | Amiloride Amiloride may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Macitentan | Macitentan Tolterodine may decrease the excretion rate of Macitentan which could result in a higher serum level. |
Flibanserin | Flibanserin Flibanserin may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Rolapitant | Rolapitant The metabolism of Tolterodine can be decreased when combined with Rolapitant. |
Brexpiprazole | Brexpiprazole Brexpiprazole may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Ziprasidone Injection | Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Ziprasidone. |
Cariprazine | Cariprazine Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Penicillin G Procaine Injection | Penicillin G Procaine Injection Tolterodine may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level. |
Eluxadoline | Eluxadoline The risk or severity of constipation can be increased when Tolterodine is combined with Eluxadoline. |
Trabectedin Injection | Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Tolterodine. |
Ixazomib | Ixazomib Tolterodine may decrease the excretion rate of Ixazomib which could result in a higher serum level. |
Lesinurad | Lesinurad Tolterodine may decrease the excretion rate of Lesinurad which could result in a higher serum level. |
Amphotericin B Liposomal Injection | Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Brivaracetam Injection | Brivaracetam Injection Brivaracetam may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Cobicistat | Cobicistat The serum concentration of Tolterodine can be increased when it is combined with Cobicistat. |
Midodrine | Midodrine The risk or severity of Tachycardia can be increased when Midodrine is combined with Tolterodine. |
Pimavanserin | Pimavanserin Pimavanserin may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Diphenhydramine Injection | Diphenhydramine Injection The metabolism of Tolterodine can be decreased when combined with Diphenhydramine. |
Furosemide Injection | Furosemide Injection Furosemide may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Rucaparib | Rucaparib The metabolism of Tolterodine can be decreased when combined with Rucaparib. |
Lixisenatide Injection | Lixisenatide Injection Tolterodine may decrease the excretion rate of Lixisenatide which could result in a higher serum level. |
Ribociclib | Ribociclib The serum concentration of Tolterodine can be increased when it is combined with Ribociclib. |
Doxepin (Insomnia) | Doxepin (Insomnia) Tolterodine may increase the central nervous system depressant (CNS depressant) activities of Doxepin. |
Plecanatide | Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Tolterodine. |
Deutetrabenazine | Deutetrabenazine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Deutetrabenazine. |
Valbenazine | Valbenazine Tolterodine may decrease the excretion rate of Valbenazine which could result in a higher serum level. |
Safinamide | Safinamide The metabolism of Tolterodine can be decreased when combined with Safinamide. |
Naldemedine | Naldemedine Tolterodine may decrease the excretion rate of Naldemedine which could result in a higher serum level. |
Midostaurin | Midostaurin The serum concentration of Tolterodine can be increased when it is combined with Midostaurin. |
Enasidenib | Enasidenib The metabolism of Tolterodine can be decreased when combined with Enasidenib. |
Benznidazole | Benznidazole Tolterodine may decrease the excretion rate of Benznidazole which could result in a higher serum level. |
Delafloxacin | Delafloxacin The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Delafloxacin. |
Letermovir | Letermovir The metabolism of Letermovir can be decreased when combined with Tolterodine. |
Tetrabenazine | Tetrabenazine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Tetrabenazine. |
Ertugliflozin | Ertugliflozin Ertugliflozin may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Buprenorphine Injection | Buprenorphine Injection The risk or severity of adverse effects can be increased when Buprenorphine is combined with Tolterodine. |
Apalutamide | Apalutamide Apalutamide may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Avatrombopag | Avatrombopag The metabolism of Tolterodine can be increased when combined with Avatrombopag. |
Baricitinib | Baricitinib Tolterodine may decrease the excretion rate of Baricitinib which could result in a higher serum level. |
Lofexidine | Lofexidine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Lofexidine. |
Plazomicin Injection | Plazomicin Injection Tolterodine may decrease the excretion rate of Plazomicin which could result in a higher serum level. |
Eliglustat | Eliglustat The metabolism of Tolterodine can be decreased when combined with Eliglustat. |
Encorafenib | Encorafenib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Encorafenib. |
Ivosidenib | Ivosidenib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Ivosidenib. |
Elagolix | Elagolix The metabolism of Elagolix can be decreased when combined with Tolterodine. |
Tafenoquine | Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Tolterodine. |
Cannabidiol | Cannabidiol The risk or severity of Tachycardia and drowsiness can be increased when Tolterodine is combined with Cannabidiol. |
Dacomitinib | Dacomitinib The metabolism of Tolterodine can be decreased when combined with Dacomitinib. |
Stiripentol | Stiripentol The serum concentration of Tolterodine can be increased when it is combined with Stiripentol. |
Gilteritinib | Gilteritinib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Gilteritinib. |
Glasdegib | Glasdegib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Glasdegib. |
Rifamycin | Rifamycin The metabolism of Tolterodine can be decreased when combined with Rifamycin. |
Prucalopride | Prucalopride Tolterodine may decrease the excretion rate of Prucalopride which could result in a higher serum level. |
Magnesium Citrate | Magnesium Citrate The therapeutic efficacy of Magnesium citrate can be decreased when used in combination with Tolterodine. |
Emapalumab-lzsg Injection | Emapalumab-lzsg Injection The metabolism of Tolterodine can be increased when combined with Emapalumab. |
Siponimod | Siponimod The metabolism of Siponimod can be decreased when combined with Tolterodine. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Erdafitinib | Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Tolterodine. |
Alpelisib | Alpelisib The serum concentration of Tolterodine can be decreased when it is combined with Alpelisib. |
Brexanolone Injection | Brexanolone Injection Brexanolone may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Solriamfetol | Solriamfetol The risk or severity of Tachycardia can be increased when Solriamfetol is combined with Tolterodine. |
Triclabendazole | Triclabendazole The metabolism of Tolterodine can be decreased when combined with Triclabendazole. |
Entrectinib | Entrectinib The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Entrectinib. |
Istradefylline | Istradefylline The metabolism of Istradefylline can be decreased when combined with Tolterodine. |
Pitolisant | Pitolisant The serum concentration of Tolterodine can be decreased when it is combined with Pitolisant. |
Fedratinib | Fedratinib The metabolism of Tolterodine can be decreased when combined with Fedratinib. |
Lefamulin | Lefamulin Lefamulin may increase the QTc-prolonging activities of Tolterodine. |
Phenytoin Injection | Phenytoin Injection The metabolism of Tolterodine can be decreased when combined with Phenytoin. |
Fosphenytoin Injection | Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Tolterodine. |
Voxelotor | Voxelotor The metabolism of Voxelotor can be decreased when combined with Tolterodine. |
Avapritinib | Avapritinib The metabolism of Avapritinib can be decreased when combined with Tolterodine. |
Lumateperone | Lumateperone Lumateperone may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Lasmiditan | Lasmiditan Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Cenobamate | Cenobamate The serum concentration of Tolterodine can be decreased when it is combined with Cenobamate. |
Selumetinib | Selumetinib The metabolism of Selumetinib can be decreased when combined with Tolterodine. |
Tucatinib | Tucatinib The metabolism of Tucatinib can be decreased when combined with Tolterodine. |
Lemborexant | Lemborexant Lemborexant may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Fenfluramine | Fenfluramine The metabolism of Tolterodine can be decreased when combined with Fenfluramine. |
Fostemsavir | Fostemsavir The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Fostemsavir. |
Octreotide | Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Tolterodine. |
Pralsetinib | Pralsetinib The metabolism of Tolterodine can be decreased when combined with Pralsetinib. |
Satralizumab-mwge Injection | Satralizumab-mwge Injection The serum concentration of Tolterodine can be decreased when it is combined with Satralizumab. |
Relugolix | Relugolix The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Relugolix. |
Progestin-Only (drospirenone) Oral Contraceptives | Progestin-Only (drospirenone) Oral Contraceptives Drospirenone may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Vibegron | Vibegron Tolterodine may increase the smooth muscle relaxing activities of Vibegron. |
Viloxazine | Viloxazine Tolterodine may increase the central nervous system depressant (CNS depressant) activities of Viloxazine. |
Tobramycin Injection | Tobramycin Injection Tobramycin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Theophylline | Theophylline The metabolism of Tolterodine can be decreased when combined with Theophylline. |
Fenoprofen | Fenoprofen Fenoprofen may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Indomethacin | Indomethacin Indomethacin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Mefenamic Acid | Mefenamic Acid Mefenamic acid may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Naproxen | Naproxen Naproxen may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Tolmetin | Tolmetin Tolmetin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Sulindac | Sulindac Sulindac may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Trazodone | Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Tolterodine. |
Isotretinoin | Isotretinoin Isotretinoin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Sucralfate | Sucralfate Sucralfate may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Hydroxyurea | Hydroxyurea The metabolism of Tolterodine can be decreased when combined with Hydroxyurea. |
Floxuridine | Floxuridine The metabolism of Tolterodine can be decreased when combined with Floxuridine. |
Phenobarbital | Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Tolterodine. |
Metaxalone | Metaxalone Metaxalone may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Methotrexate Injection | Methotrexate Injection Methotrexate may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Levorphanol | Levorphanol The risk or severity of adverse effects can be increased when Levorphanol is combined with Tolterodine. |
Primidone | Primidone Primidone may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Methsuximide | Methsuximide Methsuximide may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Diethylpropion | Diethylpropion Diethylpropion may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Chlorpromazine | Chlorpromazine The metabolism of Tolterodine can be decreased when combined with Chlorpromazine. |
Diazepam | Diazepam Diazepam may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Oxazepam | Oxazepam Oxazepam may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Flurazepam | Flurazepam Flurazepam may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Clorazepate | Clorazepate Clorazepic acid may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Lorazepam | Lorazepam Lorazepam may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Carmustine | Carmustine Carmustine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Amantadine | Amantadine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Tolterodine. |
Codeine | Codeine The risk or severity of adverse effects can be increased when Tolterodine is combined with Codeine. |
Meprobamate | Meprobamate Meprobamate may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Chlordiazepoxide | Chlordiazepoxide Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Bromocriptine | Bromocriptine Bromocriptine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Metaproterenol | Metaproterenol The risk or severity of Tachycardia can be increased when Orciprenaline is combined with Tolterodine. |
Tranylcypromine | Tranylcypromine The metabolism of Tolterodine can be decreased when combined with Tranylcypromine. |
Phenelzine | Phenelzine Phenelzine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Procarbazine | Procarbazine Procarbazine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Ergoloid Mesylates | Ergoloid Mesylates Ergoloid mesylate may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Tetracycline | Tetracycline Tetracycline may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Prochlorperazine | Prochlorperazine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Prochlorperazine. |
Thioridazine | Thioridazine The metabolism of Tolterodine can be decreased when combined with Thioridazine. |
Trifluoperazine | Trifluoperazine Trifluoperazine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Bleomycin | Bleomycin Bleomycin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Dapsone | Dapsone The metabolism of Tolterodine can be decreased when combined with Dapsone. |
Sulfadiazine | Sulfadiazine The metabolism of Tolterodine can be decreased when combined with Sulfadiazine. |
Oxycodone | Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Tolterodine. |
Methadone | Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Tolterodine. |
Oxybutynin | Oxybutynin The metabolism of Tolterodine can be decreased when combined with Oxybutynin. |
Benztropine | Benztropine The risk or severity of QTc prolongation can be increased when Benzatropine is combined with Tolterodine. |
Maprotiline | Maprotiline Maprotiline may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Ibuprofen | Ibuprofen Ibuprofen may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Trihexyphenidyl | Trihexyphenidyl The risk or severity of adverse effects can be increased when Trihexyphenidyl is combined with Tolterodine. |
Orphenadrine | Orphenadrine The metabolism of Tolterodine can be decreased when combined with Orphenadrine. |
Perphenazine | Perphenazine The metabolism of Tolterodine can be decreased when combined with Perphenazine. |
Azathioprine | Azathioprine Azathioprine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Fluphenazine | Fluphenazine Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Phentermine | Phentermine The risk or severity of Tachycardia can be increased when Phentermine is combined with Tolterodine. |
Methylphenidate | Methylphenidate Methylphenidate may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Amoxapine | Amoxapine The metabolism of Tolterodine can be decreased when combined with Amoxapine. |
Sulfasalazine | Sulfasalazine Sulfasalazine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Doxorubicin | Doxorubicin The metabolism of Tolterodine can be decreased when combined with Doxorubicin. |
Mechlorethamine | Mechlorethamine The therapeutic efficacy of Tolterodine can be decreased when used in combination with Mechlorethamine. |
Pyridostigmine | Pyridostigmine The therapeutic efficacy of Tolterodine can be decreased when used in combination with Pyridostigmine. |
Phenazopyridine | Phenazopyridine Phenazopyridine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Carbamazepine | Carbamazepine Carbamazepine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Molindone | Molindone Molindone may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Methyldopa | Methyldopa Methyldopa may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Clonidine | Clonidine The metabolism of Tolterodine can be decreased when combined with Clonidine. |
Hydralazine | Hydralazine Tolterodine may decrease the excretion rate of Hydralazine which could result in a higher serum level. |
Cimetidine | Cimetidine The metabolism of Tolterodine can be decreased when combined with Cimetidine. |
Gentamicin Injection | Gentamicin Injection Gentamicin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Warfarin | Warfarin The metabolism of Warfarin can be decreased when combined with Tolterodine. |
Clonazepam | Clonazepam Clonazepam may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Loperamide | Loperamide The serum concentration of Tolterodine can be increased when it is combined with Loperamide. |
Promethazine | Promethazine The metabolism of Tolterodine can be decreased when combined with Promethazine. |
Meclofenamate | Meclofenamate Meclofenamic acid may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Nitrofurantoin | Nitrofurantoin Nitrofurantoin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Digoxin | Digoxin Tolterodine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Loxapine | Loxapine Loxapine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Chloroquine | Chloroquine The metabolism of Tolterodine can be decreased when combined with Chloroquine. |
Quinine | Quinine The metabolism of Quinine can be decreased when combined with Tolterodine. |
Ethosuximide | Ethosuximide Ethosuximide may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Triamterene | Triamterene Triamterene may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Lactulose | Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Tolterodine. |
Sulfinpyrazone | Sulfinpyrazone The metabolism of Tolterodine can be decreased when combined with Sulfinpyrazone. |
Chlorothiazide | Chlorothiazide Tolterodine may increase the excretion rate of Chlorothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Chlorthalidone | Chlorthalidone Tolterodine may increase the excretion rate of Chlorthalidone which could result in a lower serum level and potentially a reduction in efficacy. |
Metolazone | Metolazone Metolazone may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Isosorbide | Isosorbide Isosorbide may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Secobarbital | Secobarbital Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Desipramine | Desipramine The metabolism of Desipramine can be decreased when combined with Tolterodine. |
Amitriptyline | Amitriptyline The metabolism of Tolterodine can be decreased when combined with Amitriptyline. |
Imipramine | Imipramine The metabolism of Imipramine can be decreased when combined with Tolterodine. |
Probenecid | Probenecid The metabolism of Tolterodine can be decreased when combined with Probenecid. |
Quinidine | Quinidine The metabolism of Tolterodine can be decreased when combined with Quinidine. |
Procainamide | Procainamide The metabolism of Procainamide can be decreased when combined with Tolterodine. |
Isoniazid | Isoniazid The metabolism of Tolterodine can be decreased when combined with Isoniazid. |
Pyrazinamide | Pyrazinamide Pyrazinamide may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Disopyramide | Disopyramide The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Disopyramide. |
Valproic Acid | Valproic Acid Valproic acid may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Tamoxifen | Tamoxifen The metabolism of Tolterodine can be decreased when combined with Tamoxifen. |
Butabarbital | Butabarbital Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Liothyronine | Liothyronine Liothyronine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Methimazole | Methimazole The serum concentration of Tolterodine can be increased when it is combined with Methimazole. |
Chlorpropamide | Chlorpropamide Chlorpropamide may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Glucagon Injection | Glucagon Injection Tolterodine may increase the gastrointestinal motility reducing activities of Glucagon. |
Tolbutamide | Tolbutamide Tolterodine may decrease the excretion rate of Tolbutamide which could result in a higher serum level. |
Tolazamide | Tolazamide Tolazamide may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Dextromethorphan | Dextromethorphan Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Cyclobenzaprine | Cyclobenzaprine Cyclobenzaprine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Niacin | Niacin The metabolism of Tolterodine can be decreased when combined with Niacin. |
Baclofen | Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Doxylamine | Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Cyproheptadine | Cyproheptadine Cyproheptadine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Clemastine | Clemastine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Clemastine. |
Chlorpheniramine | Chlorpheniramine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Chlorpheniramine. |
Brompheniramine | Brompheniramine Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Meclizine | Meclizine Meclizine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Ethambutol | Ethambutol Ethambutol may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Methyclothiazide | Methyclothiazide Tolterodine may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Hydrochlorothiazide | Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Dantrolene | Dantrolene Dantrolene may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Chlorzoxazone | Chlorzoxazone Chlorzoxazone may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Carisoprodol | Carisoprodol Carisoprodol may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Methocarbamol | Methocarbamol Methocarbamol may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Pyridoxine | Pyridoxine Pyridoxine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Folic Acid | Folic Acid Folic acid may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Disulfiram | Disulfiram The risk or severity of QTc prolongation can be increased when Disulfiram is combined with Tolterodine. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Propranolol. |
Pseudoephedrine | Pseudoephedrine The risk or severity of Tachycardia can be increased when Pseudoephedrine is combined with Tolterodine. |
Nortriptyline | Nortriptyline The metabolism of Tolterodine can be decreased when combined with Nortriptyline. |
Spironolactone | Spironolactone Spironolactone may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Amphotericin B Injection | Amphotericin B Injection Amphotericin B may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Phytonadione | Phytonadione Phylloquinone may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Amikacin Injection | Amikacin Injection Amikacin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Nadolol | Nadolol Tolterodine may decrease the excretion rate of Nadolol which could result in a higher serum level. |
Butorphanol Injection | Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Tolterodine. |
Nalbuphine Injection | Nalbuphine Injection The risk or severity of adverse effects can be increased when Nalbuphine is combined with Tolterodine. |
Allopurinol | Allopurinol Allopurinol may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Oxytocin Injection | Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Tolterodine. |
Trimethobenzamide | Trimethobenzamide Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Flavoxate | Flavoxate Tolterodine may decrease the excretion rate of Flavoxate which could result in a higher serum level. |
Papaverine | Papaverine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Papaverine. |
Fluorouracil Injection | Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Fluorouracil. |
Colchicine | Colchicine Tolterodine may decrease the excretion rate of Colchicine which could result in a higher serum level. |
Cefaclor | Cefaclor Cefaclor may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Cefadroxil | Cefadroxil Cefadroxil may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Cefazolin Injection | Cefazolin Injection Cefazolin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Cephalexin | Cephalexin Cephalexin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Cefoxitin Injection | Cefoxitin Injection Cefoxitin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Dacarbazine | Dacarbazine Dacarbazine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Acetazolamide | Acetazolamide Acetazolamide may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Cefotaxime Injection | Cefotaxime Injection Cefotaxime may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Calcitonin Salmon Injection | Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Ketoconazole | Ketoconazole The serum concentration of Tolterodine can be increased when it is combined with Ketoconazole. |
Pyrantel | Pyrantel Pyrantel may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Thiotepa Injection | Thiotepa Injection The therapeutic efficacy of Tolterodine can be decreased when used in combination with Thiotepa. |
Isoxsuprine | Isoxsuprine The risk or severity of Tachycardia can be increased when Tolterodine is combined with Isoxsuprine. |
Vinblastine | Vinblastine The metabolism of Tolterodine can be decreased when combined with Vinblastine. |
Ethacrynic Acid | Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Colistimethate Injection | Colistimethate Injection Colistimethate may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Metoprolol | Metoprolol The metabolism of Tolterodine can be decreased when combined with Metoprolol. |
Hydroxyzine | Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Tolterodine. |
Thiothixene | Thiothixene Tolterodine may increase the central nervous system depressant (CNS depressant) activities of Thiothixene. |
Aspirin | Aspirin Acetylsalicylic acid may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Salsalate | Salsalate Salsalate may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Alprazolam | Alprazolam Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Temazepam | Temazepam Temazepam may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Triazolam | Triazolam Triazolam may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Dicyclomine | Dicyclomine Dicyclomine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Hyoscyamine | Hyoscyamine The risk or severity of QTc prolongation can be increased when Hyoscyamine is combined with Tolterodine. |
Propantheline | Propantheline Propantheline may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Trimethoprim | Trimethoprim Trimethoprim may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Diltiazem | Diltiazem The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Diltiazem. |
Nifedipine | Nifedipine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Nifedipine. |
Timolol | Timolol The risk or severity of QTc prolongation can be increased when Timolol is combined with Tolterodine. |
Verapamil | Verapamil The metabolism of Tolterodine can be decreased when combined with Verapamil. |
Atenolol | Atenolol The metabolism of Tolterodine can be decreased when combined with Atenolol. |
Pindolol | Pindolol Pindolol may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Cisplatin Injection | Cisplatin Injection Cisplatin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Diflunisal | Diflunisal Diflunisal may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Piroxicam | Piroxicam Piroxicam may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Bumetanide | Bumetanide Bumetanide may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Glyburide | Glyburide The metabolism of Tolterodine can be decreased when combined with Glyburide. |
Glipizide | Glipizide Tolterodine may decrease the excretion rate of Glipizide which could result in a higher serum level. |
Indapamide | Indapamide Indapamide may increase the excretion rate of Tolterodine which could result in a lower serum level and potentially a reduction in efficacy. |
Amoxicillin | Amoxicillin Tolterodine may decrease the excretion rate of Amoxicillin which could result in a higher serum level. |
Oxacillin Injection | Oxacillin Injection Oxacillin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Pentoxifylline | Pentoxifylline Pentoxifylline may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Pentamidine Injection | Pentamidine Injection The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Pentamidine. |
Ceftriaxone Injection | Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Labetalol | Labetalol The metabolism of Tolterodine can be decreased when combined with Labetalol. |
Auranofin | Auranofin Auranofin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Leuprolide Injection | Leuprolide Injection The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Leuprolide. |
Gemfibrozil | Gemfibrozil The metabolism of Tolterodine can be decreased when combined with Gemfibrozil. |
Guanabenz | Guanabenz The risk or severity of Tachycardia can be increased when Guanabenz is combined with Tolterodine. |
Dipivefrin Ophthalmic | Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Ceftazidime Injection | Ceftazidime Injection Ceftazidime may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Ketoprofen | Ketoprofen Ketoprofen may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Cefotetan Injection | Cefotetan Injection Cefotetan may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Pimozide | Pimozide The metabolism of Tolterodine can be decreased when combined with Pimozide. |
Flurbiprofen | Flurbiprofen Flurbiprofen may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Amiodarone | Amiodarone The metabolism of Tolterodine can be decreased when combined with Amiodarone. |
Aztreonam Injection | Aztreonam Injection Aztreonam may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Buspirone | Buspirone Buspirone may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Lovastatin | Lovastatin The metabolism of Tolterodine can be decreased when combined with Lovastatin. |
Ciprofloxacin | Ciprofloxacin The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Ciprofloxacin. |
Mesalamine | Mesalamine Mesalazine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Diclofenac | Diclofenac Diclofenac may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Fluoxetine | Fluoxetine The serum concentration of Tolterodine can be increased when it is combined with Fluoxetine. |
Nimodipine | Nimodipine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Nimodipine. |
Clozapine | Clozapine The metabolism of Clozapine can be decreased when combined with Tolterodine. |
Estazolam | Estazolam Estazolam may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Idarubicin | Idarubicin The metabolism of Idarubicin can be decreased when combined with Tolterodine. |
Ofloxacin | Ofloxacin The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Ofloxacin. |
Didanosine | Didanosine Didanosine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Pentostatin Injection | Pentostatin Injection Pentostatin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Clarithromycin | Clarithromycin The serum concentration of Tolterodine can be increased when it is combined with Clarithromycin. |
Etodolac | Etodolac Etodolac may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Felodipine | Felodipine The metabolism of Tolterodine can be decreased when combined with Felodipine. |
Fosinopril | Fosinopril Fosinopril may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Nabumetone | Nabumetone Nabumetone may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Simvastatin | Simvastatin The metabolism of Tolterodine can be decreased when combined with Simvastatin. |
Teniposide Injection | Teniposide Injection The metabolism of Tolterodine can be decreased when combined with Teniposide. |
Itraconazole | Itraconazole The serum concentration of Tolterodine can be increased when it is combined with Itraconazole. |
Lisinopril | Lisinopril Lisinopril may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Oxaprozin | Oxaprozin Oxaprozin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Atovaquone | Atovaquone The metabolism of Tolterodine can be decreased when combined with Atovaquone. |
Sotalol | Sotalol The metabolism of Sotalol can be decreased when combined with Tolterodine. |
Bisoprolol | Bisoprolol Bisoprolol may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Zolpidem | Zolpidem Zolpidem may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Doxazosin | Doxazosin The metabolism of Tolterodine can be decreased when combined with Doxazosin. |
Isradipine | Isradipine The risk or severity of QTc prolongation can be increased when Isradipine is combined with Tolterodine. |
Omeprazole | Omeprazole The metabolism of Tolterodine can be decreased when combined with Omeprazole. |
Cisapride | Cisapride The metabolism of Tolterodine can be decreased when combined with Cisapride. |
Gabapentin | Gabapentin Gabapentin may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Fluvastatin | Fluvastatin The metabolism of Tolterodine can be decreased when combined with Fluvastatin. |
Venlafaxine | Venlafaxine The metabolism of Tolterodine can be decreased when combined with Venlafaxine. |
Nizatidine | Nizatidine The therapeutic efficacy of Tolterodine can be decreased when used in combination with Nizatidine. |
Fluvoxamine | Fluvoxamine The metabolism of Tolterodine can be decreased when combined with Fluvoxamine. |
Nefazodone | Nefazodone The serum concentration of Tolterodine can be increased when it is combined with Nefazodone. |
Lamotrigine | Lamotrigine Lamotrigine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Losartan | Losartan The risk or severity of QTc prolongation can be increased when Losartan is combined with Tolterodine. |
Valacyclovir | Valacyclovir Valaciclovir may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Tramadol | Tramadol The risk or severity of adverse effects can be increased when Tramadol is combined with Tolterodine. |
Vinorelbine Injection | Vinorelbine Injection The metabolism of Tolterodine can be decreased when combined with Vinorelbine. |
Carboplatin Injection | Carboplatin Injection Carboplatin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Moexipril | Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Tolterodine. |
Lansoprazole | Lansoprazole The metabolism of Tolterodine can be decreased when combined with Lansoprazole. |
Ifosfamide Injection | Ifosfamide Injection Tolterodine may decrease the excretion rate of Ifosfamide which could result in a higher serum level. |
Nicardipine | Nicardipine The metabolism of Tolterodine can be decreased when combined with Nicardipine. |
Bupropion | Bupropion The metabolism of Tolterodine can be decreased when combined with Bupropion. |
Ticlopidine | Ticlopidine The metabolism of Tolterodine can be decreased when combined with Ticlopidine. |
Saquinavir | Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Tolterodine. |
Metformin | Metformin Metformin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Nisoldipine | Nisoldipine Nisoldipine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Lamivudine | Lamivudine Lamivudine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Riluzole | Riluzole Riluzole may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Acarbose | Acarbose Acarbose may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Glimepiride | Glimepiride The metabolism of Tolterodine can be decreased when combined with Glimepiride. |
Gemcitabine Injection | Gemcitabine Injection Gemcitabine may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Ritonavir | Ritonavir The serum concentration of Tolterodine can be increased when it is combined with Ritonavir. |
Cidofovir Injection | Cidofovir Injection Cidofovir may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Meropenem Injection | Meropenem Injection Meropenem may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Clomipramine | Clomipramine The metabolism of Tolterodine can be decreased when combined with Clomipramine. |
Zafirlukast | Zafirlukast The metabolism of Tolterodine can be decreased when combined with Zafirlukast. |
Fosfomycin | Fosfomycin Fosfomycin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Mirtazapine | Mirtazapine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Topiramate | Topiramate The risk or severity of hyperthermia and oligohydrosis can be increased when Tolterodine is combined with Topiramate. |
Zileuton | Zileuton The metabolism of Tolterodine can be decreased when combined with Zileuton. |
Valsartan | Valsartan The metabolism of Tolterodine can be decreased when combined with Valsartan. |
Pramipexole | Pramipexole Pramipexole may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Donepezil | Donepezil The therapeutic efficacy of Tolterodine can be decreased when used in combination with Donepezil. |
Nelfinavir | Nelfinavir The metabolism of Tolterodine can be decreased when combined with Nelfinavir. |
Azithromycin | Azithromycin The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Azithromycin. |
Loratadine | Loratadine Tolterodine may increase the anticholinergic activities of Loratadine. |
Carvedilol | Carvedilol The metabolism of Carvedilol can be decreased when combined with Tolterodine. |
Nilutamide | Nilutamide The metabolism of Tolterodine can be decreased when combined with Nilutamide. |
Flutamide | Flutamide Flutamide may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Selegiline | Selegiline Selegiline may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Bicalutamide | Bicalutamide The metabolism of Tolterodine can be decreased when combined with Bicalutamide. |
Sertraline | Sertraline The metabolism of Tolterodine can be decreased when combined with Sertraline. |
Propafenone | Propafenone The metabolism of Tolterodine can be decreased when combined with Propafenone. |
Irbesartan | Irbesartan The metabolism of Tolterodine can be decreased when combined with Irbesartan. |
Tamsulosin | Tamsulosin Tamsulosin may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Ropinirole | Ropinirole Ropinirole may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Quetiapine | Quetiapine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Quetiapine. |
Cefepime Injection | Cefepime Injection Cefepime may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Cefprozil | Cefprozil Cefprozil may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Cefpodoxime | Cefpodoxime Cefpodoxime may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Cetirizine | Cetirizine Cetirizine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Paroxetine | Paroxetine The metabolism of Tolterodine can be decreased when combined with Paroxetine. |
Tolcapone | Tolcapone The metabolism of Tolterodine can be decreased when combined with Tolcapone. |
Citalopram | Citalopram The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Citalopram. |
Capecitabine | Capecitabine The metabolism of Tolterodine can be decreased when combined with Capecitabine. |
Efavirenz | Efavirenz The serum concentration of Tolterodine can be increased when it is combined with Efavirenz. |
Abacavir | Abacavir Tolterodine may decrease the excretion rate of Abacavir which could result in a higher serum level. |
Sildenafil | Sildenafil The metabolism of Tolterodine can be decreased when combined with Sildenafil. |
Celecoxib | Celecoxib The metabolism of Tolterodine can be decreased when combined with Celecoxib. |
Rosiglitazone | Rosiglitazone The metabolism of Tolterodine can be decreased when combined with Rosiglitazone. |
Thalidomide | Thalidomide Thalidomide may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Oseltamivir | Oseltamivir Oseltamivir may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Balsalazide | Balsalazide Balsalazide may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Nateglinide | Nateglinide Nateglinide may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Galantamine | Galantamine The risk or severity of QTc prolongation can be increased when Galantamine is combined with Tolterodine. |
Levetiracetam | Levetiracetam Levetiracetam may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Rabeprazole | Rabeprazole The metabolism of Rabeprazole can be decreased when combined with Tolterodine. |
Terbinafine | Terbinafine The metabolism of Tolterodine can be decreased when combined with Terbinafine. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists