Trimethobenzamide

Generic name: Pronounced as (trye meth oh ben' za mide)
Brand names
  • Tigan®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 09/15/2017

In April 2007, the Food and Drug Administration (FDA) announced that suppositories containing trimethobenzamide may no longer be marketed in the United States. The FDA made this decision because trimethobenzamide suppositories have not been shown to work to treat nausea and vomiting. If you are currently using trimethobenzamide suppositories, you should call your doctor or other healthcare professional to talk about switching to another treatment.

Trimethobenzamide is used to treat nausea and vomiting that may occur after surgery. It is also used to control nausea caused by gastroenteritis ('stomach flu'; a virus that may cause nausea, vomiting, and diarrhea). Trimethobenzamide is in a class of medications called antihistamines. Trimethobenzamide may work by decreasing activity in the area of the brain that causes nausea and vomiting.

Trimethobenzamide comes as a capsule to take by mouth. Trimethobenzamide usually is taken three or four times a day. Take trimethobenzamide at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take trimethobenzamide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking trimethobenzamide,

  • tell your doctor and pharmacist if you are allergic to trimethobenzamide or any other medications.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements and herbal products you are taking or plan to take. Be sure to mention any of the following: antidepressants; antihistamines; barbiturates such as phenobarbital (Luminal); belladonna alkaloids (Donnatal); medications for anxiety, mental illness, pain and seizures; other medications for nausea and vomiting; sedatives; sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you more carefully for side effects.

  • tell your doctor if you have Reye's Syndrome (a condition affecting the brain and liver that can happen after a viral illness), encephalitis (inflammation of the brain), or a high fever, or if you have or have ever had liver disease. If you will be giving trimethobenzamide to a child, also tell the child's doctor if the child has any of the following symptoms before he or she receives the medication: vomiting, listlessness, drowsiness, confusion, aggression, seizures, yellowing of the skin or eyes, weakness, or flu-like symptoms. Also tell the child's doctor if the child has not been drinking normally, has had excessive vomiting or diarrhea, or appears dehydrated.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking trimethobenzamide, call your doctor.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking trimethobenzamide.

  • you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.

  • ask your doctor about the safe use of alcoholic beverages while you are taking trimethobenzamide. Alcohol can make the side effects from trimethobenzamide worse.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Trimethobenzamide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • drowsiness

    • dizziness

    • headache

    • depression

    • diarrhea

  • Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

    • rash

    • backward arching of the head, neck, and back

    • muscle cramps

    • uncontrollable shaking of a part of the body

    • slow, jerking movements

    • shuffling walk

    • slow speech

    • confusion

    • blurred vision

    • yellowing of the skin or eyes

    • seizures

    • coma (loss of consciousness for a period of time)

  • Trimethobenzamide may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Dolasetron Dolasetron The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Dolasetron.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Diphenoxylate.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Guanfacine.
Naratriptan Naratriptan The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Naratriptan.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Trimethobenzamide.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Trimethobenzamide.
Reserpine Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Trimethobenzamide.
Rizatriptan Rizatriptan The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Sumatriptan.
Tizanidine Tizanidine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Tizanidine.
Zolmitriptan Zolmitriptan The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Trimethobenzamide.
Hydromorphone Injection Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Trimethobenzamide.
Meperidine Injection Meperidine Injection The risk or severity of adverse effects can be increased when Meperidine is combined with Trimethobenzamide.
Metoclopramide Injection Metoclopramide Injection The risk or severity of sedation can be increased when Metoclopramide is combined with Trimethobenzamide.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Trimethobenzamide.
Altretamine Altretamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Trimethobenzamide.
Ondansetron Ondansetron The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Ondansetron.
Granisetron Granisetron The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Granisetron.
Olanzapine Olanzapine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Alosetron Alosetron The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Alosetron.
Entacapone Entacapone The risk or severity of adverse effects can be increased when Entacapone is combined with Trimethobenzamide.
Oxcarbazepine Oxcarbazepine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Oxcarbazepine.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Zaleplon.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Desloratadine.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Trimethobenzamide.
Trimipramine Trimipramine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Trimipramine.
Glycopyrrolate Glycopyrrolate Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Epinephrine Injection Epinephrine Injection The therapeutic efficacy of Epinephrine can be increased when used in combination with Trimethobenzamide.
Escitalopram Escitalopram The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Escitalopram.
Zonisamide Zonisamide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Zonisamide.
Aripiprazole Aripiprazole Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Aripiprazole.
Atomoxetine Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Trimethobenzamide.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Dexmethylphenidate.
Almotriptan Almotriptan The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Almotriptan.
Eletriptan Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Trimethobenzamide.
Frovatriptan Frovatriptan The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Frovatriptan.
Apomorphine Injection Apomorphine Injection The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Apomorphine.
Protriptyline Protriptyline The risk or severity of adverse effects can be increased when Protriptyline is combined with Trimethobenzamide.
Duloxetine Duloxetine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Duloxetine.
Trospium Trospium Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Trimethobenzamide is combined with Eszopiclone.
Solifenacin Solifenacin Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Dextroamphetamine Dextroamphetamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Trimethobenzamide.
Sodium Oxybate Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Trimethobenzamide.
Isocarboxazid Isocarboxazid The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Isocarboxazid.
Ramelteon Ramelteon The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Ramelteon.
Darifenacin Darifenacin Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Darifenacin.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Fentanyl.
Pregabalin Pregabalin The therapeutic efficacy of Trimethobenzamide can be increased when used in combination with Pregabalin.
Felbamate Felbamate The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Felbamate.
Rasagiline Rasagiline The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Rasagiline.
Paliperidone Paliperidone The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Paliperidone.
Dimenhydrinate Dimenhydrinate The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Dimenhydrinate.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Trimethobenzamide.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Trimethobenzamide.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Levocetirizine.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Trimethobenzamide.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Trimethobenzamide.
Desvenlafaxine Desvenlafaxine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Desvenlafaxine.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Trimethobenzamide.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Midazolam.
Milnacipran Milnacipran The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Milnacipran.
Fesoterodine Fesoterodine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Iloperidone Iloperidone The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Iloperidone.
Lacosamide Lacosamide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Lacosamide.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Trimethobenzamide.
Palonosetron Injection Palonosetron Injection The risk or severity of adverse effects can be increased when Palonosetron is combined with Trimethobenzamide.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Trimethobenzamide.
Asenapine Asenapine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Asenapine.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Vigabatrin.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Oxymorphone.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Trimethobenzamide.
Lurasidone Lurasidone The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Lurasidone.
Vilazodone Vilazodone The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Vilazodone.
Clobazam Clobazam The risk or severity of adverse effects can be increased when Clobazam is combined with Trimethobenzamide.
Cabergoline Cabergoline The risk or severity of adverse effects can be increased when Cabergoline is combined with Trimethobenzamide.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Tiagabine.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Pomalidomide.
Levomilnacipran Levomilnacipran The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Levomilnacipran.
Vortioxetine Vortioxetine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Vortioxetine.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Trimethobenzamide.
Droxidopa Droxidopa The therapeutic efficacy of Droxidopa can be increased when used in combination with Trimethobenzamide.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Eslicarbazepine.
Hydrocodone Hydrocodone Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Suvorexant Suvorexant Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Methamphetamine Methamphetamine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Metamfetamine.
Tasimelteon Tasimelteon The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Tasimelteon.
Risperidone Injection Risperidone Injection The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Risperidone.
Haloperidol Injection Haloperidol Injection The risk or severity of CNS depression can be increased when Haloperidol is combined with Trimethobenzamide.
Flibanserin Flibanserin The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Flibanserin.
Brexpiprazole Brexpiprazole The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of adverse effects can be increased when Ziprasidone is combined with Trimethobenzamide.
Cariprazine Cariprazine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Cariprazine.
Brivaracetam Injection Brivaracetam Injection The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Brivaracetam.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Pimavanserin.
Diphenhydramine Injection Diphenhydramine Injection Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine.
Doxepin (Insomnia) Doxepin (Insomnia) Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Doxepin.
Safinamide Safinamide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Safinamide.
Buprenorphine Injection Buprenorphine Injection Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Lofexidine Lofexidine The therapeutic efficacy of Trimethobenzamide can be increased when used in combination with Lofexidine.
Cannabidiol Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Trimethobenzamide.
Stiripentol Stiripentol The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Stiripentol.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Brexanolone.
Solriamfetol Solriamfetol The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Solriamfetol.
Phenytoin Injection Phenytoin Injection The risk or severity of adverse effects can be increased when Phenytoin is combined with Trimethobenzamide.
Fosphenytoin Injection Fosphenytoin Injection The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Fosphenytoin.
Lumateperone Lumateperone The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Lumateperone.
Lasmiditan Lasmiditan The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Lasmiditan.
Lemborexant Lemborexant The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Lemborexant.
Fenfluramine Fenfluramine The risk or severity of adverse effects can be increased when Fenfluramine is combined with Trimethobenzamide.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Viloxazine.
Trazodone Trazodone The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Trazodone.
Phenobarbital Phenobarbital The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Phenobarbital.
Metaxalone Metaxalone The risk or severity of adverse effects can be increased when Metaxalone is combined with Trimethobenzamide.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Levorphanol.
Primidone Primidone The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Primidone.
Methsuximide Methsuximide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Methsuximide.
Diethylpropion Diethylpropion The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Diethylpropion.
Chlorpromazine Chlorpromazine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Chlorpromazine.
Diazepam Diazepam The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Diazepam.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Oxazepam.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Flurazepam.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Clorazepic acid is combined with Trimethobenzamide.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Trimethobenzamide.
Codeine Codeine The risk or severity of adverse effects can be increased when Codeine is combined with Trimethobenzamide.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Trimethobenzamide.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Trimethobenzamide.
Bromocriptine Bromocriptine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Bromocriptine.
Tranylcypromine Tranylcypromine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Tranylcypromine.
Phenelzine Phenelzine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Phenelzine.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Procarbazine.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Ergoloid mesylate.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Trimethobenzamide.
Prochlorperazine Prochlorperazine The risk or severity of adverse effects can be increased when Prochlorperazine is combined with Trimethobenzamide.
Thioridazine Thioridazine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Thioridazine.
Trifluoperazine Trifluoperazine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Trifluoperazine.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Trimethobenzamide.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Trimethobenzamide.
Oxybutynin Oxybutynin Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin.
Benztropine Benztropine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Benzatropine.
Maprotiline Maprotiline Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Maprotiline.
Trihexyphenidyl Trihexyphenidyl Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine Orphenadrine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Perphenazine.
Fluphenazine Fluphenazine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Trimethobenzamide.
Amoxapine Amoxapine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Amoxapine.
Carbamazepine Carbamazepine The risk or severity of adverse effects can be increased when Carbamazepine is combined with Trimethobenzamide.
Molindone Molindone The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Molindone.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Trimethobenzamide.
Clonazepam Clonazepam The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Clonazepam.
Promethazine Promethazine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Promethazine.
Loxapine Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Trimethobenzamide.
Quinine Quinine The risk or severity of adverse effects can be increased when Quinine is combined with Trimethobenzamide.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Ethosuximide is combined with Trimethobenzamide.
Secobarbital Secobarbital The risk or severity of adverse effects can be increased when Secobarbital is combined with Trimethobenzamide.
Desipramine Desipramine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Desipramine.
Amitriptyline Amitriptyline Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Amitriptyline.
Imipramine Imipramine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Imipramine.
Quinidine Quinidine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Quinidine.
Disopyramide Disopyramide Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Disopyramide.
Valproic Acid Valproic Acid The risk or severity of adverse effects can be increased when Valproic acid is combined with Trimethobenzamide.
Butabarbital Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Trimethobenzamide.
Dextromethorphan Dextromethorphan The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Trimethobenzamide.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Trimethobenzamide is combined with Cyclobenzaprine.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Trimethobenzamide.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Trimethobenzamide.
Cyproheptadine Cyproheptadine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine.
Clemastine Clemastine The risk or severity of adverse effects can be increased when Clemastine is combined with Trimethobenzamide.
Chlorpheniramine Chlorpheniramine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Trimethobenzamide.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Meclizine.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone The risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Trimethobenzamide.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Trimethobenzamide.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Methocarbamol is combined with Trimethobenzamide.
Nortriptyline Nortriptyline Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Nortriptyline.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Trimethobenzamide.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Nalbuphine.
Flavoxate Flavoxate Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Acetazolamide.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Pyrantel.
Hydroxyzine Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Trimethobenzamide.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Thiothixene.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Trimethobenzamide.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Trimethobenzamide.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Triazolam.
Dicyclomine Dicyclomine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine Hyoscyamine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline Propantheline Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Pindolol Pindolol The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Pindolol.
Pimozide Pimozide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Pimozide.
Fluoxetine Fluoxetine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Clozapine Clozapine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Clozapine.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Estazolam.
Zolpidem Zolpidem Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Cisapride Cisapride The risk or severity of adverse effects can be increased when Cisapride is combined with Trimethobenzamide.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Gabapentin.
Venlafaxine Venlafaxine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Trimethobenzamide.
Fluvoxamine Fluvoxamine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Fluvoxamine.
Nefazodone Nefazodone The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Nefazodone.
Lamotrigine Lamotrigine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Lamotrigine.
Tramadol Tramadol The risk or severity of CNS depression can be increased when Trimethobenzamide is combined with Tramadol.
Nicardipine Nicardipine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Nicardipine.
Bupropion Bupropion The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Bupropion.
Riluzole Riluzole The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Riluzole.
Clomipramine Clomipramine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Clomipramine.
Mirtazapine Mirtazapine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Trimethobenzamide.
Pramipexole Pramipexole Trimethobenzamide may increase the sedative activities of Pramipexole.
Donepezil Donepezil The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Donepezil.
Selegiline Selegiline The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Selegiline.
Sertraline Sertraline The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Sertraline.
Ropinirole Ropinirole Trimethobenzamide may increase the sedative activities of Ropinirole.
Quetiapine Quetiapine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Quetiapine.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Trimethobenzamide.
Paroxetine Paroxetine The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Paroxetine.
Tolcapone Tolcapone The risk or severity of adverse effects can be increased when Tolcapone is combined with Trimethobenzamide.
Citalopram Citalopram The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Citalopram.
Efavirenz Efavirenz The risk or severity of adverse effects can be increased when Efavirenz is combined with Trimethobenzamide.
Tolterodine Tolterodine Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
Thalidomide Thalidomide Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Levetiracetam.

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