Venlafaxine

Venlafaxine is used to treat depression. Venlafaxine extended-release (long-acting) capsules are also used to treat generalized anxiety disorder (GAD; excessive worrying that is difficult to control), social anxiety disorder (extreme fear of interacting with others or performing in front of others that interferes with normal life), and panic disorder (sudden, unexpected attacks of extreme fear and worry about these attacks). Venlafaxine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SNRIs). It works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance.

Venlafaxine comes as a tablet or extended-release capsule to take by mouth. The tablet is usually taken two or three times a day with food. The extended-release capsule is usually taken once daily in the morning or evening with food. Take venlafaxine at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take venlafaxine exactly as directed. Do not take more or less of it or take it more often or for a longer period of time than prescribed by your doctor.

Swallow the extended-release capsule whole; do not split, chew, or crush it, or place it in water. If you cannot swallow the extended-release capsule, you may carefully open the capsule and sprinkle the entire contents on a spoonful of applesauce. Swallow (without chewing) this mixture immediately after preparation and then drink a glass of water to make sure that you have swallowed all of the medication.

Your doctor will probably start you on a low dose of venlafaxine and gradually increase your dose, not more often than once every 4 to 7 days. Tell your doctor how you are feeling during your treatment so that your doctor can adjust your dose properly.

Venlafaxine controls depression but does not cure it. It may take several weeks or longer for you to feel the full benefit of this medication. Continue to take venlafaxine even if you feel well. Do not stop taking venlafaxine without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking venlafaxine, you may experience withdrawal symptoms such as agitation; anxiety; tiredness; confusion; mood changes; headache; dizziness; irritability; frenzied or abnormal excitement; lack of coordination; trouble falling asleep or staying asleep; nightmares; nausea; vomiting; loss of appetite; diarrhea; dry mouth; sweating; uncontrollable shaking of a part of the body; ringing in the ears; blurred vision; seizures; or burning, tingling, numbness, or electric shock-like feelings in any part of the body. Tell your doctor if you experience any of these symptoms while you are decreasing your dose of venlafaxine or soon after you stop taking venlafaxine.

Venlafaxine is also sometimes used to treat hot flashes (hot flushes; sudden strong feelings of heat and sweating) in women who have experienced menopause ('change of life'; the end of monthly menstrual periods) or who are taking medication to treat breast cancer. Talk to your doctor or pharmacist about the risks of using venlafaxine to treat your condition.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking venlafaxine,

• tell your doctor and pharmacist if you are allergic to venlafaxine, any other medications, or any of the ingredients in venlafaxine tablets or extended-release capsules. Ask your pharmacist for a list of the ingredients.

• you should know that desvenlafaxine is very similar to another SNRI, desvenlafaxine (Pristiq). You should not take these medications together.

• tell your doctor if you are taking a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or if you have stopped taking one of these medications within the past 14 days. Your doctor will probably tell you that you should not take venlafaxine. If you stop taking venlafaxine, your doctor will tell you that you should wait at least 7 days before you start to take an MAO inhibitor.

• tell your doctor and pharmacist what other prescription and nonprescription medications, and vitamins you are taking or plan to take. Be sure to mention any of the following: amphetamines such as amphetamine (in Adderall, in Mydayis), dextroamphetamine (Dexedrine, in Adderall), and methamphetamine (Desoxyn); anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); buspirone; cimetidine (Tagamet); clozapine (Clozaril); diuretics ('water pills'); fentanyl (Actiq, Duragesic, Fentora, Subsys); haloperidol (Haldol); indinavir (Crixivan); ketoconazole; lithium; medications for anxiety, mental illness, pain, seizures, or weight loss; medications for migraine such as almotriptan, eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); metoprolol (Kapspargo Sprinkle, Lopressor, Toprol); mirtazapine (Remeron); phentermine (Adipex P, Lomaira, Qsymia); sedatives; selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, in Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft); other SNRIs such as duloxetine (Cymbalta); sleeping pills; tramadol (Conzip, Qdola, Ultram in Ultracet); tranquilizers, and tricyclic antidepressants such as amitriptyline, amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline, and trimipramine. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

• tell your doctor what nutritional supplements and herbal products you are taking, especially St. John's wort and tryptophan.

• tell your doctor if you have ever used illegal drugs or overused prescription medications. Also tell your doctor if you have recently had a heart attack and if you have or have ever had high blood pressure, high blood cholesterol seizures, glaucoma (increased pressure in the eye that may cause loss of sight), or heart, kidney, liver, or thyroid disease.

• tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, or if you plan to become pregnant or are breast-feeding. If you become pregnant while taking venlafaxine, call your doctor. Venlafaxine may cause problems in newborns following delivery if it is taken during the last months of pregnancy.

• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking venlafaxine.

• you should know that this medication may make you drowsy and may affect your judgment, thinking, and movements. Do not drive a car or operate machinery until you know how this medication affects you.

• remember that alcohol can add to the drowsiness caused by this medication.

• you should know that venlafaxine may cause high blood pressure. You should have your blood pressure checked before starting treatment and regularly while you are taking this medication.

• you should know that venlafaxine may cause angle-closure glaucoma (a condition where the fluid is suddenly blocked and unable to flow out of the eye causing a quick, severe increase in eye pressure which may lead to a loss of vision). Talk to your doctor about having an eye examination before you start taking this medication. If you have nausea, eye pain, changes in vision, such as seeing colored rings around lights, and swelling or redness in or around the eye, call your doctor or get emergency medical treatment right away.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are taking the extended-release capsules, do not take more than one dose per day.

• Venlafaxine may cause side effects. Call your doctor if any of the following symptoms are severe or do not go away:

  • drowsiness

  • weakness or tiredness

  • dizziness

  • headache

  • nightmares

  • nausea

  • vomiting

  • stomach pain

  • constipation

  • diarrhea

  • gas

  • heartburn

  • burping

  • dry mouth

  • change in ability to taste food

  • loss of appetite

  • weight loss

  • uncontrollable shaking of a part of the body

  • pain, burning, numbness, or tingling in part of the body

  • yawning

  • sweating

  • hot flashes or flushing

  • frequent urination

  • difficulty urinating

  • sore throat, chills, or other signs of infection

  • ringing in the ears

  • sexual problems in males; decreased sex drive, inability to get or keep an erection, or delayed or absent ejaculation

  • sexual problems in females; decreased sex drive, or delayed orgasm or unable to have an orgasm

  • enlarged pupils (black circles in the middle of the eyes)

• Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING or SPECIAL PRECAUTIONS sections, call your doctor immediately:

  • rash

  • hives

  • itching

  • difficulty breathing or swallowing

  • chest pain

  • fast, pounding, or irregular heartbeat

  • seizures

  • unusual bruising or bleeding

  • small purple spots on the skin

  • fever, sweating, confusion, fast or irregular heartbeat, severe muscle stiffness or twitching, nausea, vomiting, or diarrhea

  • problems with coordination

  • hallucinations (seeing things or hearing voices that do not exist)

  • coma (loss of consciousness for a period of time)

• Venlafaxine may slow growth and weight gain in children. If your child is taking venlafaxine, your child's doctor will watch your child's growth carefully. Talk to your child's doctor about the risks of giving venlafaxine to your child.

• Venlafaxine may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

• If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

• dizziness

• nausea

• vomiting

• burning, tingling, or numbness of the hands and feet

• increased size of the pupil (black center of the eye)

• muscle pain

• hot and cold spells

• sleepiness

• seizures

• fast, slow, or irregular heartbeat

• coma (loss of consciousness for a period of time)

Keep all appointments with your doctor and the laboratory.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug	Interaction
Moxifloxacin	Moxifloxacin The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Moxifloxacin.
Repaglinide	Repaglinide The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Repaglinide.
Montelukast	Montelukast The metabolism of Montelukast can be decreased when combined with Venlafaxine.
Insulin Glargine (rDNA origin) Injection	Insulin Glargine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Insulin glargine is combined with Venlafaxine.
Leflunomide	Leflunomide The metabolism of Venlafaxine can be decreased when combined with Leflunomide.
Delavirdine	Delavirdine The metabolism of Venlafaxine can be decreased when combined with Delavirdine.
Nevirapine	Nevirapine The metabolism of Venlafaxine can be decreased when combined with Nevirapine.
Dolasetron	Dolasetron The metabolism of Dolasetron can be decreased when combined with Venlafaxine.
Anagrelide	Anagrelide The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Anagrelide.
Candesartan	Candesartan The metabolism of Venlafaxine can be decreased when combined with Candesartan.
Cilostazol	Cilostazol The metabolism of Cilostazol can be decreased when combined with Venlafaxine.
Clopidogrel	Clopidogrel The metabolism of Venlafaxine can be decreased when combined with Clopidogrel.
Diphenoxylate	Diphenoxylate The risk or severity of adverse effects can be increased when Venlafaxine is combined with Diphenoxylate.
Erythromycin and Sulfisoxazole	Erythromycin and Sulfisoxazole The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives)	Estrogen and Progestin (Oral Contraceptives) Venlafaxine may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate	Fenofibrate The metabolism of Venlafaxine can be decreased when combined with Fenofibrate.
Guanfacine	Guanfacine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Guanfacine.
Magnesium Hydroxide	Magnesium Hydroxide Venlafaxine may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Miglitol	Miglitol The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Miglitol.
Mycophenolate	Mycophenolate Venlafaxine may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level.
Naratriptan	Naratriptan The risk or severity of adverse effects can be increased when Venlafaxine is combined with Naratriptan.
Olsalazine	Olsalazine Olsalazine may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Paregoric	Paregoric The risk or severity of adverse effects can be increased when Venlafaxine is combined with Morphine.
Penbutolol	Penbutolol The metabolism of Acebutolol can be decreased when combined with Venlafaxine.
Pentazocine	Pentazocine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Pentazocine.
Potassium	Potassium Potassium may increase the excretion rate of Venlafaxine which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone	Prednisone Venlafaxine may decrease the excretion rate of Prednisone which could result in a higher serum level.
Ranitidine	Ranitidine The metabolism of Venlafaxine can be decreased when combined with Ranitidine.
Reserpine	Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Venlafaxine.
Rizatriptan	Rizatriptan The risk or severity of adverse effects can be increased when Venlafaxine is combined with Rizatriptan.
Sumatriptan	Sumatriptan The risk or severity of adverse effects can be increased when Venlafaxine is combined with Sumatriptan.
Tacrolimus	Tacrolimus Tacrolimus may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Tizanidine	Tizanidine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Tizanidine.
Zolmitriptan	Zolmitriptan The risk or severity of serotonin syndrome can be increased when Venlafaxine is combined with Zolmitriptan.
Ampicillin Injection	Ampicillin Injection Venlafaxine may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Doxycycline Injection	Doxycycline Injection Doxycycline may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Famotidine Injection	Famotidine Injection The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Famotidine.
Fluconazole Injection	Fluconazole Injection The metabolism of Venlafaxine can be decreased when combined with Fluconazole.
Foscarnet Injection	Foscarnet Injection Foscarnet may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Hydromorphone Injection	Hydromorphone Injection The risk or severity of adverse effects can be increased when Venlafaxine is combined with Hydromorphone.
Levofloxacin Injection	Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Levofloxacin.
Meperidine Injection	Meperidine Injection The metabolism of Meperidine can be decreased when combined with Venlafaxine.
Metoclopramide Injection	Metoclopramide Injection The risk or severity of adverse effects can be increased when Metoclopramide is combined with Venlafaxine.
Metronidazole Injection	Metronidazole Injection The metabolism of Venlafaxine can be decreased when combined with Metronidazole.
Morphine Injection	Morphine Injection The risk or severity of adverse effects can be increased when Venlafaxine is combined with Morphine.
Pamidronate Injection	Pamidronate Injection Pamidronic acid may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Vancomycin Injection	Vancomycin Injection Venlafaxine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Zidovudine Injection	Zidovudine Injection Venlafaxine may increase the excretion rate of Zidovudine which could result in a lower serum level and potentially a reduction in efficacy.
Altretamine	Altretamine The metabolism of Venlafaxine can be decreased when combined with Amphetamine.
Cefuroxime	Cefuroxime Cefuroxime may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Cyclosporine	Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Venlafaxine.
Ondansetron	Ondansetron The metabolism of Ondansetron can be decreased when combined with Venlafaxine.
Enoxaparin Injection	Enoxaparin Injection Venlafaxine may increase the antiplatelet activities of Enoxaparin.
Granisetron	Granisetron The risk or severity of adverse effects can be increased when Venlafaxine is combined with Granisetron.
Torsemide	Torsemide The metabolism of Venlafaxine can be decreased when combined with Torasemide.
Olanzapine	Olanzapine The metabolism of Olanzapine can be decreased when combined with Venlafaxine.
Alosetron	Alosetron The risk or severity of adverse effects can be increased when Venlafaxine is combined with Alosetron.
Dofetilide	Dofetilide The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Dofetilide.
Entacapone	Entacapone The risk or severity of adverse effects can be increased when Venlafaxine is combined with Entacapone.
Hydroxychloroquine	Hydroxychloroquine The metabolism of Venlafaxine can be decreased when combined with Hydroxychloroquine.
Meloxicam	Meloxicam Venlafaxine may increase the antiplatelet activities of Meloxicam.
Oxcarbazepine	Oxcarbazepine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Oxcarbazepine.
Pantoprazole	Pantoprazole Pantoprazole may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Temozolomide	Temozolomide Venlafaxine may decrease the excretion rate of Temozolomide which could result in a higher serum level.
Zaleplon	Zaleplon The risk or severity of adverse effects can be increased when Venlafaxine is combined with Zaleplon.
Anakinra	Anakinra The metabolism of Venlafaxine can be increased when combined with Anakinra.
Desloratadine	Desloratadine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Desloratadine.
Linezolid	Linezolid Linezolid may increase the serotonergic activities of Venlafaxine.
Pentosan Polysulfate	Pentosan Polysulfate Venlafaxine may increase the antiplatelet activities of Pentosan polysulfate.
Trimipramine	Trimipramine The metabolism of Trimipramine can be decreased when combined with Venlafaxine.
Etanercept Injection	Etanercept Injection The metabolism of Venlafaxine can be increased when combined with Etanercept.
Glycopyrrolate	Glycopyrrolate Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Modafinil	Modafinil The metabolism of Venlafaxine can be decreased when combined with Armodafinil.
Perindopril	Perindopril Venlafaxine may decrease the excretion rate of Perindopril which could result in a higher serum level.
Tenofovir	Tenofovir Tenofovir may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Choline Magnesium Trisalicylate	Choline Magnesium Trisalicylate Venlafaxine may increase the antiplatelet activities of Choline magnesium trisalicylate.
Epinephrine Injection	Epinephrine Injection Venlafaxine may increase the tachycardic activities of Epinephrine.
Eplerenone	Eplerenone Eplerenone may increase the excretion rate of Venlafaxine which could result in a lower serum level and potentially a reduction in efficacy.
Escitalopram	Escitalopram The risk or severity of serotonin syndrome can be increased when Venlafaxine is combined with Escitalopram.
Zonisamide	Zonisamide The risk or severity of adverse effects can be increased when Venlafaxine is combined with Zonisamide.
Adalimumab Injection	Adalimumab Injection The metabolism of Venlafaxine can be increased when combined with Adalimumab.
Aripiprazole	Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Venlafaxine.
Atomoxetine	Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Venlafaxine.
Dexmethylphenidate	Dexmethylphenidate The risk or severity of adverse effects can be increased when Venlafaxine is combined with Dexmethylphenidate.
Ezetimibe	Ezetimibe Venlafaxine may increase the excretion rate of Ezetimibe which could result in a lower serum level and potentially a reduction in efficacy.
Atazanavir	Atazanavir The metabolism of Venlafaxine can be decreased when combined with Atazanavir.
Almotriptan	Almotriptan The metabolism of Almotriptan can be decreased when combined with Venlafaxine.
Eletriptan	Eletriptan The metabolism of Eletriptan can be decreased when combined with Venlafaxine.
Mefloquine	Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Venlafaxine.
Rosuvastatin	Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Venlafaxine.
Vardenafil	Vardenafil The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Vardenafil.
Alfuzosin	Alfuzosin The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Alfuzosin.
Aprepitant	Aprepitant The metabolism of Venlafaxine can be decreased when combined with Aprepitant.
Emtricitabine	Emtricitabine Venlafaxine may decrease the excretion rate of Emtricitabine which could result in a higher serum level.
Memantine	Memantine Venlafaxine may decrease the excretion rate of Memantine which could result in a higher serum level.
Tegaserod	Tegaserod The metabolism of Tegaserod can be decreased when combined with Venlafaxine.
Tadalafil	Tadalafil Venlafaxine may decrease the excretion rate of Tadalafil which could result in a higher serum level.
Frovatriptan	Frovatriptan The risk or severity of adverse effects can be increased when Venlafaxine is combined with Frovatriptan.
Gemifloxacin	Gemifloxacin The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Gemifloxacin.
Progesterone	Progesterone The metabolism of Progesterone can be decreased when combined with Venlafaxine.
Apomorphine Injection	Apomorphine Injection The risk or severity of adverse effects can be increased when Venlafaxine is combined with Apomorphine.
Infliximab Injection	Infliximab Injection The metabolism of Venlafaxine can be increased when combined with Infliximab.
Oxandrolone	Oxandrolone The metabolism of Venlafaxine can be decreased when combined with Oxandrolone.
Protriptyline	Protriptyline The metabolism of Protriptyline can be decreased when combined with Venlafaxine.
Duloxetine	Duloxetine The metabolism of Duloxetine can be decreased when combined with Venlafaxine.
Tinidazole	Tinidazole Venlafaxine may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Trospium	Trospium Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Bosentan	Bosentan The metabolism of Venlafaxine can be increased when combined with Bosentan.
Cefditoren	Cefditoren Venlafaxine may decrease the excretion rate of Cefdinir which could result in a higher serum level.
Cinacalcet	Cinacalcet The metabolism of Venlafaxine can be decreased when combined with Cinacalcet.
Cyanocobalamin Injection	Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Erlotinib	Erlotinib The metabolism of Erlotinib can be decreased when combined with Venlafaxine.
Eszopiclone	Eszopiclone The risk or severity of CNS depression can be increased when Venlafaxine is combined with Eszopiclone.
Ganciclovir	Ganciclovir Venlafaxine may decrease the excretion rate of Ganciclovir which could result in a higher serum level.
Insulin Aspart (rDNA Origin) Injection	Insulin Aspart (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Insulin aspart.
Ribavirin	Ribavirin Venlafaxine may decrease the excretion rate of Ribavirin which could result in a higher serum level.
Solifenacin	Solifenacin The metabolism of Solifenacin can be decreased when combined with Venlafaxine.
Valganciclovir	Valganciclovir Venlafaxine may decrease the excretion rate of Valganciclovir which could result in a higher serum level.
Voriconazole	Voriconazole The risk or severity of adverse effects can be increased when Voriconazole is combined with Venlafaxine.
Adefovir	Adefovir Adefovir may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Dextroamphetamine	Dextroamphetamine The metabolism of Venlafaxine can be decreased when combined with Amphetamine.
Peginterferon Alfa-2b (PEG-Intron)	Peginterferon Alfa-2b (PEG-Intron) The metabolism of Venlafaxine can be increased when combined with Peginterferon alfa-2b.
Pramlintide Injection	Pramlintide Injection The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Pramlintide.
Sodium Oxybate	Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Venlafaxine.
Exenatide Injection	Exenatide Injection The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Exenatide.
Ibandronate	Ibandronate The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Ibandronate.
Isocarboxazid	Isocarboxazid Venlafaxine may increase the serotonergic activities of Isocarboxazid.
Ramelteon	Ramelteon The risk or severity of adverse effects can be increased when Venlafaxine is combined with Ramelteon.
Darifenacin	Darifenacin The metabolism of Darifenacin can be decreased when combined with Venlafaxine.
Fentanyl	Fentanyl The risk or severity of adverse effects can be increased when Venlafaxine is combined with Fentanyl.
Pregabalin	Pregabalin The therapeutic efficacy of Venlafaxine can be increased when used in combination with Pregabalin.
Phenylephrine	Phenylephrine Venlafaxine may increase the tachycardic activities of Phenylephrine.
Tipranavir	Tipranavir The metabolism of Tipranavir can be decreased when combined with Venlafaxine.
Felbamate	Felbamate The risk or severity of adverse effects can be increased when Venlafaxine is combined with Felbamate.
Insulin Detemir (rDNA Origin) Injection	Insulin Detemir (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Insulin detemir.
Ranolazine	Ranolazine The serum concentration of Ranolazine can be increased when it is combined with Venlafaxine.
Abatacept Injection	Abatacept Injection The metabolism of Venlafaxine can be increased when combined with Abatacept.
Rasagiline	Rasagiline Rasagiline may increase the serotonergic activities of Venlafaxine.
Imatinib	Imatinib The metabolism of Imatinib can be decreased when combined with Venlafaxine.
Sitagliptin	Sitagliptin The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Sitagliptin.
Varenicline	Varenicline Venlafaxine may decrease the excretion rate of Varenicline which could result in a higher serum level.
Gefitinib	Gefitinib The metabolism of Gefitinib can be decreased when combined with Venlafaxine.
Albuterol	Albuterol Venlafaxine may increase the tachycardic activities of Salbutamol.
Paliperidone	Paliperidone The metabolism of Paliperidone can be decreased when combined with Venlafaxine.
Bortezomib	Bortezomib The metabolism of Venlafaxine can be decreased when combined with Bortezomib.
Clofarabine Injection	Clofarabine Injection Venlafaxine may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Insulin Glulisine (rDNA origin) Injection	Insulin Glulisine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Insulin glulisine.
Lubiprostone	Lubiprostone Venlafaxine may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
Oxaliplatin Injection	Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Oxaliplatin.
Posaconazole	Posaconazole The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Posaconazole.
Primaquine	Primaquine The metabolism of Venlafaxine can be decreased when combined with Primaquine.
Pemetrexed Injection	Pemetrexed Injection Venlafaxine may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Dimenhydrinate	Dimenhydrinate The risk or severity of adverse effects can be increased when Venlafaxine is combined with Dimenhydrinate.
Lisdexamfetamine	Lisdexamfetamine The metabolism of Lisdexamfetamine can be decreased when combined with Venlafaxine.
Nabilone	Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Venlafaxine.
Vorinostat	Vorinostat The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Vorinostat.
Sorafenib	Sorafenib The metabolism of Venlafaxine can be decreased when combined with Sorafenib.
Sunitinib	Sunitinib The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Sunitinib.
Dronabinol	Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Venlafaxine.
Lapatinib	Lapatinib The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Lapatinib.
Levocetirizine	Levocetirizine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Levocetirizine.
Pegaptanib Injection	Pegaptanib Injection Venlafaxine may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Dasatinib	Dasatinib The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Dasatinib.
Mexiletine	Mexiletine The metabolism of Mexiletine can be decreased when combined with Venlafaxine.
Armodafinil	Armodafinil The metabolism of Venlafaxine can be decreased when combined with Armodafinil.
Azacitidine Injection	Azacitidine Injection Venlafaxine may decrease the excretion rate of Azacitidine which could result in a higher serum level.
Ivermectin	Ivermectin Venlafaxine may increase the excretion rate of Ivermectin which could result in a lower serum level and potentially a reduction in efficacy.
Temsirolimus	Temsirolimus The metabolism of Venlafaxine can be decreased when combined with Temsirolimus.
Lenalidomide	Lenalidomide Venlafaxine may decrease the excretion rate of Lenalidomide which could result in a higher serum level.
Nilotinib	Nilotinib The metabolism of Nilotinib can be decreased when combined with Venlafaxine.
Toremifene	Toremifene The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Toremifene.
Bexarotene	Bexarotene The metabolism of Bexarotene can be decreased when combined with Venlafaxine.
Budesonide	Budesonide Venlafaxine may decrease the excretion rate of Budesonide which could result in a higher serum level.
Desmopressin	Desmopressin Desmopressin may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
OnabotulinumtoxinA Injection	OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Venlafaxine.
RimabotulinumtoxinB Injection	RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Venlafaxine.
Doripenem Injection	Doripenem Injection Venlafaxine may decrease the excretion rate of Doripenem which could result in a higher serum level.
Etravirine	Etravirine The metabolism of Venlafaxine can be decreased when combined with Etravirine.
Arsenic Trioxide Injection	Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Arsenic trioxide.
Mitoxantrone Injection	Mitoxantrone Injection Venlafaxine may increase the excretion rate of Mitoxantrone which could result in a lower serum level and potentially a reduction in efficacy.
Desvenlafaxine	Desvenlafaxine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Desvenlafaxine.
Cevimeline	Cevimeline The metabolism of Venlafaxine can be decreased when combined with Cevimeline.
Nebivolol	Nebivolol The metabolism of Nebivolol can be decreased when combined with Venlafaxine.
Tretinoin	Tretinoin The metabolism of Tretinoin can be decreased when combined with Venlafaxine.
Flecainide	Flecainide The metabolism of Flecainide can be decreased when combined with Venlafaxine.
Certolizumab Injection	Certolizumab Injection The metabolism of Venlafaxine can be increased when combined with Certolizumab pegol.
Irinotecan Injection	Irinotecan Injection Venlafaxine may increase the excretion rate of Irinotecan which could result in a lower serum level and potentially a reduction in efficacy.
Daptomycin Injection	Daptomycin Injection Daptomycin may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Methylnaltrexone Injection	Methylnaltrexone Injection Venlafaxine may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Rufinamide	Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Venlafaxine.
Midazolam	Midazolam The risk or severity of adverse effects can be increased when Venlafaxine is combined with Midazolam.
Naltrexone Injection	Naltrexone Injection The risk or severity of serotonin syndrome can be increased when Venlafaxine is combined with Naltrexone.
Dexrazoxane Injection	Dexrazoxane Injection Venlafaxine may decrease the excretion rate of Dexrazoxane which could result in a higher serum level.
Milnacipran	Milnacipran The risk or severity of adverse effects can be increased when Venlafaxine is combined with Milnacipran.
Plerixafor Injection	Plerixafor Injection Venlafaxine may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Fesoterodine	Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Venlafaxine.
Degarelix Injection	Degarelix Injection The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Degarelix.
Betaxolol	Betaxolol The metabolism of Betaxolol can be decreased when combined with Venlafaxine.
Iloperidone	Iloperidone The metabolism of Iloperidone can be decreased when combined with Venlafaxine.
Prasugrel	Prasugrel Venlafaxine may increase the antiplatelet activities of Prasugrel.
Lacosamide	Lacosamide The risk or severity of adverse effects can be increased when Venlafaxine is combined with Lacosamide.
Everolimus	Everolimus The metabolism of Venlafaxine can be decreased when combined with Everolimus.
Tolvaptan (low blood sodium)	Tolvaptan (low blood sodium) Tolvaptan may increase the excretion rate of Venlafaxine which could result in a lower serum level and potentially a reduction in efficacy.
Dronedarone	Dronedarone The metabolism of Dronedarone can be decreased when combined with Venlafaxine.
AbobotulinumtoxinA Injection	AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Venlafaxine.
Pralatrexate Injection	Pralatrexate Injection Venlafaxine may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection	Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Venlafaxine.
Saxagliptin	Saxagliptin The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Saxagliptin.
Telavancin Injection	Telavancin Injection The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Telavancin.
Romidepsin Injection	Romidepsin Injection The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Romidepsin.
Tapentadol	Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Venlafaxine.
Topotecan	Topotecan Venlafaxine may decrease the excretion rate of Topotecan which could result in a higher serum level.
Golimumab Injection	Golimumab Injection The metabolism of Venlafaxine can be increased when combined with Golimumab.
Pazopanib	Pazopanib The metabolism of Pazopanib can be decreased when combined with Venlafaxine.
Asenapine	Asenapine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Asenapine.
Vigabatrin	Vigabatrin The risk or severity of adverse effects can be increased when Venlafaxine is combined with Vigabatrin.
Pitavastatin	Pitavastatin Venlafaxine may increase the excretion rate of Pitavastatin which could result in a lower serum level and potentially a reduction in efficacy.
Oxymorphone	Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Venlafaxine.
Dabigatran	Dabigatran Venlafaxine may increase the antiplatelet activities of Dabigatran.
Liraglutide Injection	Liraglutide Injection The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Liraglutide.
Tocilizumab Injection	Tocilizumab Injection The metabolism of Venlafaxine can be increased when combined with Tocilizumab.
Dalfampridine	Dalfampridine The risk or severity of seizure can be increased when Venlafaxine is combined with Dalfampridine.
Eribulin Injection	Eribulin Injection The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Eribulin.
IncobotulinumtoxinA Injection	IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Venlafaxine.
Ceftaroline Injection	Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Lurasidone	Lurasidone The risk or severity of adverse effects can be increased when Venlafaxine is combined with Lurasidone.
Acetaminophen Injection	Acetaminophen Injection The metabolism of Acetaminophen can be decreased when combined with Venlafaxine.
Vilazodone	Vilazodone The metabolism of Vilazodone can be decreased when combined with Venlafaxine.
Ipilimumab Injection	Ipilimumab Injection Venlafaxine may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection	Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Terbutaline Injection	Terbutaline Injection Venlafaxine may increase the tachycardic activities of Terbutaline.
Roflumilast	Roflumilast Venlafaxine may decrease the excretion rate of Roflumilast which could result in a higher serum level.
Linagliptin	Linagliptin The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Linagliptin.
Rilpivirine	Rilpivirine The metabolism of Rilpivirine can be decreased when combined with Venlafaxine.
Telaprevir	Telaprevir Venlafaxine may increase the excretion rate of Glecaprevir which could result in a lower serum level and potentially a reduction in efficacy.
Cyclophosphamide Injection	Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Venlafaxine.
Abiraterone	Abiraterone The metabolism of Venlafaxine can be decreased when combined with Abiraterone.
Triptorelin Injection	Triptorelin Injection The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Triptorelin.
Rivaroxaban	Rivaroxaban Venlafaxine may increase the antiplatelet activities of Rivaroxaban.
Ticagrelor	Ticagrelor Venlafaxine may increase the antiplatelet activities of Ticagrelor.
Ruxolitinib	Ruxolitinib Venlafaxine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Vandetanib	Vandetanib The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Vandetanib.
Clobazam	Clobazam The metabolism of Clobazam can be decreased when combined with Venlafaxine.
Vemurafenib	Vemurafenib The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Vemurafenib.
Vismodegib	Vismodegib The metabolism of Venlafaxine can be decreased when combined with Vismodegib.
Deferiprone	Deferiprone Venlafaxine may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Crizotinib	Crizotinib The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Crizotinib.
Cabergoline	Cabergoline The risk or severity of serotonin syndrome can be increased when Cabergoline is combined with Venlafaxine.
Naloxone Injection	Naloxone Injection Venlafaxine may decrease the excretion rate of Naloxone which could result in a higher serum level.
Fondaparinux Injection	Fondaparinux Injection Venlafaxine may increase the antiplatelet activities of Fondaparinux.
Ezogabine	Ezogabine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Tiagabine.
Iloprost	Iloprost Venlafaxine may increase the antiplatelet activities of Iloprost.
Enzalutamide	Enzalutamide The metabolism of Venlafaxine can be increased when combined with Enzalutamide.
Mirabegron	Mirabegron The metabolism of Mirabegron can be decreased when combined with Venlafaxine.
Regorafenib	Regorafenib The metabolism of Venlafaxine can be decreased when combined with Regorafenib.
Teriflunomide	Teriflunomide Venlafaxine may increase the excretion rate of Teriflunomide which could result in a lower serum level and potentially a reduction in efficacy.
Lorcaserin	Lorcaserin The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Mecasermin.
Cabozantinib (thyroid cancer)	Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Venlafaxine.
Teduglutide Injection	Teduglutide Injection Venlafaxine may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Bedaquiline	Bedaquiline The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Bedaquiline.
Icosapent Ethyl	Icosapent Ethyl Venlafaxine may increase the antiplatelet activities of Icosapent ethyl.
Alogliptin	Alogliptin The metabolism of Alogliptin can be decreased when combined with Venlafaxine.
Ponatinib	Ponatinib The metabolism of Ponatinib can be decreased when combined with Venlafaxine.
Pomalidomide	Pomalidomide The risk or severity of adverse effects can be increased when Venlafaxine is combined with Pomalidomide.
Apixaban	Apixaban Venlafaxine may increase the antiplatelet activities of Apixaban.
Canagliflozin	Canagliflozin The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Canagliflozin.
Methazolamide	Methazolamide Methazolamide may increase the excretion rate of Venlafaxine which could result in a lower serum level and potentially a reduction in efficacy.
Dabrafenib	Dabrafenib The metabolism of Venlafaxine can be increased when combined with Dabrafenib.
Ospemifene	Ospemifene The metabolism of Venlafaxine can be decreased when combined with Ospemifene.
Trametinib	Trametinib Venlafaxine may decrease the excretion rate of Trametinib which could result in a higher serum level.
Dolutegravir	Dolutegravir Venlafaxine may increase the excretion rate of Dolutegravir which could result in a lower serum level and potentially a reduction in efficacy.
Afatinib	Afatinib Venlafaxine may increase the excretion rate of Afatinib which could result in a lower serum level and potentially a reduction in efficacy.
Levomilnacipran	Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Venlafaxine.
Ertapenem Injection	Ertapenem Injection Venlafaxine may decrease the excretion rate of Ertapenem which could result in a higher serum level.
Vortioxetine	Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Venlafaxine.
Perampanel	Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Venlafaxine.
Ibrutinib	Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Venlafaxine.
Ketorolac Injection	Ketorolac Injection Venlafaxine may increase the antiplatelet activities of Ketorolac.
Simeprevir	Simeprevir Venlafaxine may increase the excretion rate of Simeprevir which could result in a lower serum level and potentially a reduction in efficacy.
Sofosbuvir	Sofosbuvir Venlafaxine may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin	Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Venlafaxine.
Apremilast	Apremilast The metabolism of Venlafaxine can be increased when combined with Apremilast.
Droxidopa	Droxidopa Venlafaxine may increase the tachycardic activities of Droxidopa.
Ceritinib	Ceritinib The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Ceritinib.
Siltuximab Injection	Siltuximab Injection The metabolism of Venlafaxine can be increased when combined with Siltuximab.
Albiglutide Injection	Albiglutide Injection The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Albiglutide.
Eslicarbazepine	Eslicarbazepine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Eslicarbazepine.
Idelalisib	Idelalisib Venlafaxine may increase the excretion rate of Idelalisib which could result in a lower serum level and potentially a reduction in efficacy.
Testosterone Injection	Testosterone Injection Venlafaxine may decrease the excretion rate of Testosterone which could result in a higher serum level.
Oritavancin Injection	Oritavancin Injection The metabolism of Venlafaxine can be decreased when combined with Oritavancin.
Empagliflozin	Empagliflozin The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Empagliflozin.
Vorapaxar	Vorapaxar Venlafaxine may increase the antiplatelet activities of Vorapaxar.
Hydrocodone	Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Venlafaxine.
Suvorexant	Suvorexant Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Dulaglutide Injection	Dulaglutide Injection The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Dulaglutide.
Edoxaban	Edoxaban Venlafaxine may increase the antiplatelet activities of Edoxaban.
Methamphetamine	Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Venlafaxine.
Tasimelteon	Tasimelteon The risk or severity of adverse effects can be increased when Venlafaxine is combined with Tasimelteon.
Riociguat	Riociguat Venlafaxine may increase the excretion rate of Riociguat which could result in a lower serum level and potentially a reduction in efficacy.
Lanreotide Injection	Lanreotide Injection The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Lanreotide.
Secukinumab Injection	Secukinumab Injection The metabolism of Venlafaxine can be increased when combined with Secukinumab.
Risperidone Injection	Risperidone Injection The metabolism of Risperidone can be decreased when combined with Venlafaxine.
Palbociclib	Palbociclib Venlafaxine may increase the excretion rate of Palbociclib which could result in a lower serum level and potentially a reduction in efficacy.
Insulin Human Inhalation	Insulin Human Inhalation The risk or severity of hypoglycemia can be increased when Insulin human is combined with Venlafaxine.
Lenvatinib	Lenvatinib The metabolism of Lenvatinib can be decreased when combined with Venlafaxine.
Naloxegol	Naloxegol The metabolism of Venlafaxine can be decreased when combined with Naloxegol.
Panobinostat	Panobinostat The metabolism of Panobinostat can be decreased when combined with Venlafaxine.
Haloperidol Injection	Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Venlafaxine.
Ivabradine	Ivabradine The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Ivabradine.
Amiloride	Amiloride Amiloride may increase the excretion rate of Venlafaxine which could result in a lower serum level and potentially a reduction in efficacy.
Macitentan	Macitentan Venlafaxine may decrease the excretion rate of Macitentan which could result in a higher serum level.
Flibanserin	Flibanserin The risk or severity of adverse effects can be increased when Venlafaxine is combined with Flibanserin.
Rolapitant	Rolapitant The metabolism of Venlafaxine can be decreased when combined with Rolapitant.
Brexpiprazole	Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Venlafaxine.
Ziprasidone Injection	Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Ziprasidone is combined with Venlafaxine.
Cariprazine	Cariprazine The metabolism of Cariprazine can be decreased when combined with Venlafaxine.
Penicillin G Procaine Injection	Penicillin G Procaine Injection Venlafaxine may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Eluxadoline	Eluxadoline The risk or severity of serotonin syndrome can be increased when Venlafaxine is combined with Eluxadoline.
Insulin Degludec (rDNA Origin) Injection	Insulin Degludec (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Insulin degludec.
Trabectedin Injection	Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Venlafaxine.
Osimertinib	Osimertinib Venlafaxine may increase the excretion rate of Osimertinib which could result in a lower serum level and potentially a reduction in efficacy.
Ixazomib	Ixazomib Venlafaxine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lesinurad	Lesinurad Venlafaxine may decrease the excretion rate of Lesinurad which could result in a higher serum level.
Amphotericin B Liposomal Injection	Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Defibrotide Injection	Defibrotide Injection Venlafaxine may increase the antiplatelet activities of Defibrotide.
Brivaracetam Injection	Brivaracetam Injection The risk or severity of adverse effects can be increased when Venlafaxine is combined with Brivaracetam.
Venetoclax	Venetoclax Venlafaxine may increase the excretion rate of Venetoclax which could result in a lower serum level and potentially a reduction in efficacy.
Cobicistat	Cobicistat The metabolism of Venlafaxine can be decreased when combined with Cobicistat.
Midodrine	Midodrine Venlafaxine may increase the tachycardic activities of Midodrine.
Pimavanserin	Pimavanserin The risk or severity of adverse effects can be increased when Venlafaxine is combined with Pimavanserin.
Diphenhydramine Injection	Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Venlafaxine.
Furosemide Injection	Furosemide Injection Venlafaxine may increase the excretion rate of Furosemide which could result in a lower serum level and potentially a reduction in efficacy.
Rucaparib	Rucaparib The metabolism of Venlafaxine can be decreased when combined with Rucaparib.
Lixisenatide Injection	Lixisenatide Injection The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Lixisenatide.
Ribociclib	Ribociclib The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Ribociclib.
Brigatinib	Brigatinib Venlafaxine may increase the excretion rate of Brigatinib which could result in a lower serum level and potentially a reduction in efficacy.
Doxepin (Insomnia)	Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Venlafaxine.
Deutetrabenazine	Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Venlafaxine.
Valbenazine	Valbenazine The metabolism of Valbenazine can be decreased when combined with Venlafaxine.
Safinamide	Safinamide Safinamide may increase the serotonergic activities of Venlafaxine.
Naldemedine	Naldemedine Venlafaxine may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Midostaurin	Midostaurin The metabolism of Venlafaxine can be decreased when combined with Midostaurin.
Enasidenib	Enasidenib The metabolism of Venlafaxine can be decreased when combined with Enasidenib.
Benznidazole	Benznidazole Venlafaxine may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Copanlisib Injection	Copanlisib Injection Venlafaxine may increase the excretion rate of Copanlisib which could result in a lower serum level and potentially a reduction in efficacy.
Delafloxacin	Delafloxacin The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Delafloxacin.
Abemaciclib	Abemaciclib Venlafaxine may increase the excretion rate of Abemaciclib which could result in a lower serum level and potentially a reduction in efficacy.
Betrixaban	Betrixaban The risk or severity of bleeding can be increased when Venlafaxine is combined with Betrixaban.
Letermovir	Letermovir The metabolism of Letermovir can be decreased when combined with Venlafaxine.
Semaglutide Injection	Semaglutide Injection The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Semaglutide.
Tetrabenazine	Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Venlafaxine.
Ertugliflozin	Ertugliflozin The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Ertugliflozin.
Buprenorphine Injection	Buprenorphine Injection Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Apalutamide	Apalutamide Apalutamide may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Avatrombopag	Avatrombopag The metabolism of Venlafaxine can be increased when combined with Avatrombopag.
Baricitinib	Baricitinib Venlafaxine may decrease the excretion rate of Baricitinib which could result in a higher serum level.
Lofexidine	Lofexidine The therapeutic efficacy of Venlafaxine can be increased when used in combination with Lofexidine.
Plazomicin Injection	Plazomicin Injection Venlafaxine may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Eliglustat	Eliglustat The metabolism of Eliglustat can be decreased when combined with Venlafaxine.
Encorafenib	Encorafenib The metabolism of Encorafenib can be decreased when combined with Venlafaxine.
Ivosidenib	Ivosidenib The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Ivosidenib.
Lusutrombopag	Lusutrombopag Venlafaxine may increase the excretion rate of Lusutrombopag which could result in a lower serum level and potentially a reduction in efficacy.
Elagolix	Elagolix The metabolism of Elagolix can be decreased when combined with Venlafaxine.
Tafenoquine	Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Venlafaxine.
Cannabidiol	Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Venlafaxine.
Dacomitinib	Dacomitinib The metabolism of Venlafaxine can be decreased when combined with Dacomitinib.
Duvelisib	Duvelisib Venlafaxine may increase the excretion rate of Duvelisib which could result in a lower serum level and potentially a reduction in efficacy.
Stiripentol	Stiripentol The metabolism of Venlafaxine can be decreased when combined with Stiripentol.
Talazoparib	Talazoparib Venlafaxine may increase the excretion rate of Talazoparib which could result in a lower serum level and potentially a reduction in efficacy.
Gilteritinib	Gilteritinib The therapeutic efficacy of Venlafaxine can be decreased when used in combination with Gilteritinib.
Glasdegib	Glasdegib The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Glasdegib.
Rifamycin	Rifamycin The metabolism of Venlafaxine can be decreased when combined with Rifamycin.
Prucalopride	Prucalopride Venlafaxine may decrease the excretion rate of Prucalopride which could result in a higher serum level.
Emapalumab-lzsg Injection	Emapalumab-lzsg Injection The metabolism of Venlafaxine can be increased when combined with Emapalumab.
Siponimod	Siponimod The metabolism of Siponimod can be decreased when combined with Venlafaxine.
Acyclovir Ophthalmic	Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Caplacizumab-yhdp Injection	Caplacizumab-yhdp Injection Venlafaxine may increase the antiplatelet activities of Caplacizumab.
Erdafitinib	Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Venlafaxine.
Alpelisib	Alpelisib The serum concentration of Venlafaxine can be decreased when it is combined with Alpelisib.
Brexanolone Injection	Brexanolone Injection The risk or severity of adverse effects can be increased when Venlafaxine is combined with Brexanolone.
Cladribine	Cladribine Venlafaxine may increase the excretion rate of Cladribine which could result in a lower serum level and potentially a reduction in efficacy.
Solriamfetol	Solriamfetol The risk or severity of Tachycardia can be increased when Solriamfetol is combined with Venlafaxine.
Darolutamide	Darolutamide Venlafaxine may increase the excretion rate of Darolutamide which could result in a lower serum level and potentially a reduction in efficacy.
Triclabendazole	Triclabendazole The metabolism of Venlafaxine can be decreased when combined with Triclabendazole.
Entrectinib	Entrectinib The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Entrectinib.
Istradefylline	Istradefylline The metabolism of Istradefylline can be decreased when combined with Venlafaxine.
Pitolisant	Pitolisant The serum concentration of Venlafaxine can be decreased when it is combined with Pitolisant.
Fedratinib	Fedratinib The metabolism of Venlafaxine can be decreased when combined with Fedratinib.
Lefamulin	Lefamulin Venlafaxine may increase the QTc-prolonging activities of Lefamulin.
Phenytoin Injection	Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Venlafaxine.
Fosphenytoin Injection	Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Venlafaxine.
Voxelotor	Voxelotor The metabolism of Voxelotor can be decreased when combined with Venlafaxine.
Avapritinib	Avapritinib The metabolism of Avapritinib can be decreased when combined with Venlafaxine.
Lumateperone	Lumateperone The risk or severity of adverse effects can be increased when Venlafaxine is combined with Lumateperone.
Lasmiditan	Lasmiditan The risk or severity of serotonin syndrome can be increased when Venlafaxine is combined with Lasmiditan.
Ubrogepant	Ubrogepant Venlafaxine may increase the excretion rate of Ubrogepant which could result in a lower serum level and potentially a reduction in efficacy.
Tazemetostat	Tazemetostat Venlafaxine may increase the excretion rate of Tazemetostat which could result in a lower serum level and potentially a reduction in efficacy.
Cenobamate	Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Venlafaxine.
Ozanimod	Ozanimod Venlafaxine may increase the excretion rate of Ozanimod which could result in a lower serum level and potentially a reduction in efficacy.
Selumetinib	Selumetinib Venlafaxine may increase the excretion rate of Selumetinib which could result in a lower serum level and potentially a reduction in efficacy.
Rimegepant	Rimegepant Venlafaxine may increase the excretion rate of Rimegepant which could result in a lower serum level and potentially a reduction in efficacy.
Tucatinib	Tucatinib The metabolism of Tucatinib can be decreased when combined with Venlafaxine.
Ripretinib	Ripretinib Venlafaxine may increase the excretion rate of Ripretinib which could result in a lower serum level and potentially a reduction in efficacy.
Lemborexant	Lemborexant The risk or severity of adverse effects can be increased when Venlafaxine is combined with Lemborexant.
Fenfluramine	Fenfluramine The risk or severity of serotonin syndrome can be increased when Venlafaxine is combined with Fenfluramine.
Fostemsavir	Fostemsavir The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Fostemsavir.
Octreotide	Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Venlafaxine.
Pralsetinib	Pralsetinib The metabolism of Pralsetinib can be decreased when combined with Venlafaxine.
Satralizumab-mwge Injection	Satralizumab-mwge Injection The serum concentration of Venlafaxine can be decreased when it is combined with Satralizumab.
Relugolix	Relugolix The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Relugolix.
Progestin-Only (drospirenone) Oral Contraceptives	Progestin-Only (drospirenone) Oral Contraceptives Drospirenone may increase the excretion rate of Venlafaxine which could result in a lower serum level and potentially a reduction in efficacy.
Viloxazine	Viloxazine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Viloxazine.
Tobramycin Injection	Tobramycin Injection Tobramycin may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Theophylline	Theophylline The metabolism of Theophylline can be decreased when combined with Venlafaxine.
Fenoprofen	Fenoprofen Venlafaxine may increase the antiplatelet activities of Fenoprofen.
Indomethacin	Indomethacin Venlafaxine may decrease the excretion rate of Indomethacin which could result in a higher serum level.
Mefenamic Acid	Mefenamic Acid Venlafaxine may increase the antiplatelet activities of Mefenamic acid.
Naproxen	Naproxen Venlafaxine may increase the antiplatelet activities of Naproxen.
Tolmetin	Tolmetin Venlafaxine may increase the antiplatelet activities of Tolmetin.
Sulindac	Sulindac Venlafaxine may increase the antiplatelet activities of Sulindac.
Trazodone	Trazodone Venlafaxine may increase the serotonergic activities of Trazodone.
Isotretinoin	Isotretinoin Venlafaxine may decrease the excretion rate of Isotretinoin which could result in a higher serum level.
Sucralfate	Sucralfate Venlafaxine may decrease the excretion rate of Sucralfate which could result in a higher serum level.
Hydroxyurea	Hydroxyurea The metabolism of Venlafaxine can be decreased when combined with Hydroxyurea.
Floxuridine	Floxuridine The metabolism of Venlafaxine can be decreased when combined with Floxuridine.
Phenobarbital	Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Venlafaxine.
Metaxalone	Metaxalone The risk or severity of adverse effects can be increased when Venlafaxine is combined with Metaxalone.
Methotrexate Injection	Methotrexate Injection Venlafaxine may decrease the excretion rate of Methotrexate which could result in a higher serum level.
Levorphanol	Levorphanol The risk or severity of adverse effects can be increased when Venlafaxine is combined with Levorphanol.
Primidone	Primidone The risk or severity of adverse effects can be increased when Venlafaxine is combined with Primidone.
Methsuximide	Methsuximide The risk or severity of adverse effects can be increased when Venlafaxine is combined with Methsuximide.
Diethylpropion	Diethylpropion The risk or severity of adverse effects can be increased when Venlafaxine is combined with Diethylpropion.
Chlorpromazine	Chlorpromazine The metabolism of Chlorpromazine can be decreased when combined with Venlafaxine.
Diazepam	Diazepam The risk or severity of adverse effects can be increased when Venlafaxine is combined with Diazepam.
Oxazepam	Oxazepam The risk or severity of adverse effects can be increased when Venlafaxine is combined with Oxazepam.
Flurazepam	Flurazepam The risk or severity of adverse effects can be increased when Venlafaxine is combined with Flurazepam.
Clorazepate	Clorazepate The risk or severity of adverse effects can be increased when Venlafaxine is combined with Clorazepic acid.
Lorazepam	Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Venlafaxine.
Carmustine	Carmustine Carmustine may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Amantadine	Amantadine The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Amantadine.
Codeine	Codeine The metabolism of Codeine can be decreased when combined with Venlafaxine.
Meprobamate	Meprobamate The risk or severity of adverse effects can be increased when Venlafaxine is combined with Meprobamate.
Chlordiazepoxide	Chlordiazepoxide The risk or severity of adverse effects can be increased when Venlafaxine is combined with Chlordiazepoxide.
Bromocriptine	Bromocriptine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Bromocriptine.
Metaproterenol	Metaproterenol Venlafaxine may increase the tachycardic activities of Orciprenaline.
Tranylcypromine	Tranylcypromine The metabolism of Tranylcypromine can be decreased when combined with Venlafaxine.
Phenelzine	Phenelzine Venlafaxine may increase the serotonergic activities of Phenelzine.
Procarbazine	Procarbazine Procarbazine may increase the serotonergic activities of Venlafaxine.
Ergoloid Mesylates	Ergoloid Mesylates The risk or severity of adverse effects can be increased when Venlafaxine is combined with Ergoloid mesylate.
Tetracycline	Tetracycline Venlafaxine may decrease the excretion rate of Tetracycline which could result in a higher serum level.
Minocycline	Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Venlafaxine.
Prochlorperazine	Prochlorperazine The metabolism of Prochlorperazine can be decreased when combined with Venlafaxine.
Thioridazine	Thioridazine The metabolism of Thioridazine can be decreased when combined with Venlafaxine.
Trifluoperazine	Trifluoperazine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Trifluoperazine.
Bleomycin	Bleomycin Venlafaxine may decrease the excretion rate of Bleomycin which could result in a higher serum level.
Dapsone	Dapsone The metabolism of Venlafaxine can be decreased when combined with Dapsone.
Sulfadiazine	Sulfadiazine The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Sulfadiazine.
Oxycodone	Oxycodone The metabolism of Oxycodone can be decreased when combined with Venlafaxine.
Methadone	Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Venlafaxine.
Oxybutynin	Oxybutynin The metabolism of Venlafaxine can be decreased when combined with Oxybutynin.
Benztropine	Benztropine The metabolism of Venlafaxine can be decreased when combined with Benzatropine.
Maprotiline	Maprotiline The metabolism of Maprotiline can be decreased when combined with Venlafaxine.
Ibuprofen	Ibuprofen Venlafaxine may decrease the excretion rate of Ibuprofen which could result in a higher serum level.
Trihexyphenidyl	Trihexyphenidyl Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine	Orphenadrine Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine	Perphenazine The metabolism of Perphenazine can be decreased when combined with Venlafaxine.
Azathioprine	Azathioprine Venlafaxine may decrease the excretion rate of Azathioprine which could result in a higher serum level.
Fluphenazine	Fluphenazine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Fluphenazine.
Phentermine	Phentermine The risk or severity of serotonin syndrome can be increased when Phentermine is combined with Venlafaxine.
Methylphenidate	Methylphenidate Venlafaxine may decrease the excretion rate of Methylphenidate which could result in a higher serum level.
Amoxapine	Amoxapine The metabolism of Amoxapine can be decreased when combined with Venlafaxine.
Sulfasalazine	Sulfasalazine Venlafaxine may increase the antiplatelet activities of Sulfasalazine.
Doxorubicin	Doxorubicin The metabolism of Doxorubicin can be decreased when combined with Venlafaxine.
Dactinomycin	Dactinomycin Venlafaxine may increase the excretion rate of Dactinomycin which could result in a lower serum level and potentially a reduction in efficacy.
Phenazopyridine	Phenazopyridine Phenazopyridine may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Carbamazepine	Carbamazepine Venlafaxine may decrease the excretion rate of Carbamazepine which could result in a higher serum level.
Molindone	Molindone The risk or severity of adverse effects can be increased when Venlafaxine is combined with Molindone.
Methyldopa	Methyldopa Venlafaxine may increase the tachycardic activities of Methyldopa.
Clonidine	Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Venlafaxine.
Prazosin	Prazosin Venlafaxine may increase the excretion rate of Prazosin which could result in a lower serum level and potentially a reduction in efficacy.
Hydralazine	Hydralazine Venlafaxine may decrease the excretion rate of Hydralazine which could result in a higher serum level.
Cimetidine	Cimetidine The metabolism of Cimetidine can be decreased when combined with Venlafaxine.
Gentamicin Injection	Gentamicin Injection Gentamicin may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Warfarin	Warfarin The metabolism of Venlafaxine can be decreased when combined with Warfarin.
Clonazepam	Clonazepam The risk or severity of adverse effects can be increased when Venlafaxine is combined with Clonazepam.
Loperamide	Loperamide The metabolism of Venlafaxine can be decreased when combined with Loperamide.
Promethazine	Promethazine The metabolism of Promethazine can be decreased when combined with Venlafaxine.
Meclofenamate	Meclofenamate Venlafaxine may increase the antiplatelet activities of Meclofenamic acid.
Daunorubicin	Daunorubicin Venlafaxine may increase the excretion rate of Daunorubicin which could result in a lower serum level and potentially a reduction in efficacy.
Nitrofurantoin	Nitrofurantoin Venlafaxine may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Digoxin	Digoxin Venlafaxine may decrease the excretion rate of Digoxin which could result in a higher serum level.
Loxapine	Loxapine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Loxapine.
Chloroquine	Chloroquine The metabolism of Chloroquine can be decreased when combined with Venlafaxine.
Quinine	Quinine The metabolism of Quinine can be decreased when combined with Venlafaxine.
Ethosuximide	Ethosuximide The risk or severity of adverse effects can be increased when Venlafaxine is combined with Ethosuximide.
Triamterene	Triamterene Triamterene may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Sulfinpyrazone	Sulfinpyrazone The metabolism of Venlafaxine can be decreased when combined with Sulfinpyrazone.
Chlorothiazide	Chlorothiazide Chlorothiazide may increase the excretion rate of Venlafaxine which could result in a lower serum level and potentially a reduction in efficacy.
Chlorthalidone	Chlorthalidone Chlorthalidone may increase the excretion rate of Venlafaxine which could result in a lower serum level and potentially a reduction in efficacy.
Metolazone	Metolazone Venlafaxine may increase the excretion rate of Metolazone which could result in a lower serum level and potentially a reduction in efficacy.
Isosorbide	Isosorbide Isosorbide may increase the excretion rate of Venlafaxine which could result in a lower serum level and potentially a reduction in efficacy.
Secobarbital	Secobarbital The risk or severity of adverse effects can be increased when Venlafaxine is combined with Secobarbital.
Desipramine	Desipramine The serum concentration of the active metabolites of Desipramine can be increased when Desipramine is used in combination with Venlafaxine.
Amitriptyline	Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Venlafaxine.
Imipramine	Imipramine The metabolism of Imipramine can be decreased when combined with Venlafaxine.
Probenecid	Probenecid The metabolism of Probenecid can be decreased when combined with Venlafaxine.
Quinidine	Quinidine The metabolism of Venlafaxine can be decreased when combined with Quinidine.
Procainamide	Procainamide The metabolism of Procainamide can be decreased when combined with Venlafaxine.
Isoniazid	Isoniazid The metabolism of Venlafaxine can be decreased when combined with Isoniazid.
Pyrazinamide	Pyrazinamide Venlafaxine may decrease the excretion rate of Pyrazinamide which could result in a higher serum level.
Disopyramide	Disopyramide The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Disopyramide.
Valproic Acid	Valproic Acid The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Valproic acid.
Tamoxifen	Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Venlafaxine.
Butabarbital	Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Venlafaxine.
Liothyronine	Liothyronine Liothyronine may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Methimazole	Methimazole The metabolism of Venlafaxine can be decreased when combined with Methimazole.
Chlorpropamide	Chlorpropamide The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Chlorpropamide.
Tolbutamide	Tolbutamide The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Tolbutamide.
Tolazamide	Tolazamide The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Tolazamide.
Dextromethorphan	Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Venlafaxine.
Cyclobenzaprine	Cyclobenzaprine The risk or severity of CNS depression can be increased when Venlafaxine is combined with Cyclobenzaprine.
Niacin	Niacin The metabolism of Venlafaxine can be decreased when combined with Niacin.
Baclofen	Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Venlafaxine.
Doxylamine	Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Venlafaxine.
Cyproheptadine	Cyproheptadine Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine.
Clemastine	Clemastine The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Clemastine.
Chlorpheniramine	Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Venlafaxine.
Brompheniramine	Brompheniramine Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Brompheniramine.
Meclizine	Meclizine The metabolism of Meclizine can be decreased when combined with Venlafaxine.
Ethambutol	Ethambutol Venlafaxine may decrease the excretion rate of Ethambutol which could result in a higher serum level.
Methyclothiazide	Methyclothiazide Methyclothiazide may increase the excretion rate of Venlafaxine which could result in a lower serum level and potentially a reduction in efficacy.
Hydrochlorothiazide	Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Dantrolene	Dantrolene The risk or severity of adverse effects can be increased when Venlafaxine is combined with Dantrolene.
Chlorzoxazone	Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Venlafaxine.
Carisoprodol	Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Venlafaxine.
Methocarbamol	Methocarbamol The risk or severity of adverse effects can be increased when Venlafaxine is combined with Methocarbamol.
Pyridoxine	Pyridoxine Pyridoxine may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Folic Acid	Folic Acid Folic acid may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Disulfiram	Disulfiram The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Disulfiram.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The metabolism of Propranolol can be decreased when combined with Venlafaxine.
Pseudoephedrine	Pseudoephedrine The risk or severity of serotonin syndrome can be increased when Venlafaxine is combined with Pseudoephedrine.
Nortriptyline	Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Venlafaxine.
Spironolactone	Spironolactone Spironolactone may increase the excretion rate of Venlafaxine which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection	Amphotericin B Injection Amphotericin B may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Phytonadione	Phytonadione Venlafaxine may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
Amikacin Injection	Amikacin Injection Amikacin may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Nadolol	Nadolol The metabolism of Nadolol can be decreased when combined with Venlafaxine.
Butorphanol Injection	Butorphanol Injection The risk or severity of adverse effects can be increased when Venlafaxine is combined with Butorphanol.
Nalbuphine Injection	Nalbuphine Injection The risk or severity of adverse effects can be increased when Venlafaxine is combined with Nalbuphine.
Allopurinol	Allopurinol Venlafaxine may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Oxytocin Injection	Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Venlafaxine.
Trimethobenzamide	Trimethobenzamide The risk or severity of adverse effects can be increased when Venlafaxine is combined with Trimethobenzamide.
Flavoxate	Flavoxate Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Papaverine	Papaverine The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Papaverine.
Fluorouracil Injection	Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Fluorouracil.
Colchicine	Colchicine Venlafaxine may decrease the excretion rate of Colchicine which could result in a higher serum level.
Cefaclor	Cefaclor Cefaclor may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Cefadroxil	Cefadroxil Cefadroxil may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Cefazolin Injection	Cefazolin Injection Cefazolin may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Cephalexin	Cephalexin Cephalexin may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Cefoxitin Injection	Cefoxitin Injection Cefoxitin may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Dacarbazine	Dacarbazine Venlafaxine may decrease the excretion rate of Dacarbazine which could result in a higher serum level.
Acetazolamide	Acetazolamide The risk or severity of adverse effects can be increased when Venlafaxine is combined with Acetazolamide.
Cefotaxime Injection	Cefotaxime Injection Cefotaxime may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Calcitonin Salmon Injection	Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Ketoconazole	Ketoconazole The serum concentration of Venlafaxine can be increased when it is combined with Ketoconazole.
Pyrantel	Pyrantel The risk or severity of adverse effects can be increased when Venlafaxine is combined with Pyrantel.
Vincristine Injection	Vincristine Injection Venlafaxine may increase the excretion rate of Vincristine which could result in a lower serum level and potentially a reduction in efficacy.
Dipyridamole	Dipyridamole Venlafaxine may increase the antiplatelet activities of Dipyridamole.
Isoxsuprine	Isoxsuprine Venlafaxine may increase the tachycardic activities of Isoxsuprine.
Vinblastine	Vinblastine The metabolism of Venlafaxine can be decreased when combined with Vinblastine.
Ethacrynic Acid	Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Colistimethate Injection	Colistimethate Injection Colistimethate may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Metoprolol	Metoprolol The serum concentration of Venlafaxine can be increased when it is combined with Metoprolol.
Hydroxyzine	Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Venlafaxine.
Thiothixene	Thiothixene The risk or severity of adverse effects can be increased when Venlafaxine is combined with Thiothixene.
Aspirin	Aspirin Venlafaxine may increase the antiplatelet activities of Acetylsalicylic acid.
Salsalate	Salsalate Venlafaxine may increase the antiplatelet activities of Salsalate.
Alprazolam	Alprazolam The risk or severity of adverse effects can be increased when Venlafaxine is combined with Alprazolam.
Temazepam	Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Venlafaxine.
Triazolam	Triazolam The risk or severity of adverse effects can be increased when Venlafaxine is combined with Triazolam.
Dicyclomine	Dicyclomine Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine	Hyoscyamine Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline	Propantheline Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Trimethoprim	Trimethoprim Venlafaxine may decrease the excretion rate of Trimethoprim which could result in a higher serum level.
Diltiazem	Diltiazem The metabolism of Diltiazem can be decreased when combined with Venlafaxine.
Nifedipine	Nifedipine The metabolism of Nifedipine can be decreased when combined with Venlafaxine.
Timolol	Timolol The metabolism of Timolol can be decreased when combined with Venlafaxine.
Verapamil	Verapamil The metabolism of Venlafaxine can be decreased when combined with Verapamil.
Atenolol	Atenolol The metabolism of Atenolol can be decreased when combined with Venlafaxine.
Pindolol	Pindolol The metabolism of Pindolol can be decreased when combined with Venlafaxine.
Cisplatin Injection	Cisplatin Injection Venlafaxine may decrease the excretion rate of Cisplatin which could result in a higher serum level.
Diflunisal	Diflunisal Venlafaxine may increase the antiplatelet activities of Diflunisal.
Piroxicam	Piroxicam Venlafaxine may increase the antiplatelet activities of Piroxicam.
Bumetanide	Bumetanide Venlafaxine may increase the excretion rate of Bumetanide which could result in a lower serum level and potentially a reduction in efficacy.
Etoposide	Etoposide Venlafaxine may increase the excretion rate of Etoposide which could result in a lower serum level and potentially a reduction in efficacy.
Glyburide	Glyburide The metabolism of Glyburide can be decreased when combined with Venlafaxine.
Glipizide	Glipizide The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Glipizide.
Indapamide	Indapamide Venlafaxine may increase the excretion rate of Indapamide which could result in a lower serum level and potentially a reduction in efficacy.
Amoxicillin	Amoxicillin Venlafaxine may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Oxacillin Injection	Oxacillin Injection Venlafaxine may decrease the excretion rate of Oxacillin which could result in a higher serum level.
Pentoxifylline	Pentoxifylline Venlafaxine may increase the antiplatelet activities of Pentoxifylline.
Pentamidine Injection	Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Venlafaxine.
Ceftriaxone Injection	Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Labetalol	Labetalol The metabolism of Labetalol can be decreased when combined with Venlafaxine.
Auranofin	Auranofin Venlafaxine may decrease the excretion rate of Auranofin which could result in a higher serum level.
Leuprolide Injection	Leuprolide Injection The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Leuprolide.
Gemfibrozil	Gemfibrozil The metabolism of Venlafaxine can be decreased when combined with Gemfibrozil.
Guanabenz	Guanabenz Venlafaxine may increase the tachycardic activities of Guanabenz.
Dipivefrin Ophthalmic	Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Ceftazidime Injection	Ceftazidime Injection Ceftazidime may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Ketoprofen	Ketoprofen Venlafaxine may increase the antiplatelet activities of Ketoprofen.
Cefotetan Injection	Cefotetan Injection Cefotetan may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Pimozide	Pimozide The metabolism of Pimozide can be decreased when combined with Venlafaxine.
Flurbiprofen	Flurbiprofen Venlafaxine may increase the antiplatelet activities of Flurbiprofen.
Amiodarone	Amiodarone The metabolism of Venlafaxine can be decreased when combined with Amiodarone.
Aztreonam Injection	Aztreonam Injection Venlafaxine may decrease the excretion rate of Aztreonam which could result in a higher serum level.
Buspirone	Buspirone The metabolism of Buspirone can be decreased when combined with Venlafaxine.
Lovastatin	Lovastatin The metabolism of Lovastatin can be decreased when combined with Venlafaxine.
Ciprofloxacin	Ciprofloxacin The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Ciprofloxacin.
Mesalamine	Mesalamine Venlafaxine may increase the antiplatelet activities of Mesalazine.
Diclofenac	Diclofenac Venlafaxine may increase the antiplatelet activities of Diclofenac.
Fluoxetine	Fluoxetine The serum concentration of Fluoxetine can be increased when it is combined with Venlafaxine.
Nimodipine	Nimodipine The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Nimodipine.
Clozapine	Clozapine The metabolism of Clozapine can be decreased when combined with Venlafaxine.
Estazolam	Estazolam The risk or severity of adverse effects can be increased when Venlafaxine is combined with Estazolam.
Idarubicin	Idarubicin The metabolism of Idarubicin can be decreased when combined with Venlafaxine.
Ofloxacin	Ofloxacin The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Ofloxacin.
Didanosine	Didanosine Venlafaxine may decrease the excretion rate of Didanosine which could result in a higher serum level.
Pentostatin Injection	Pentostatin Injection Venlafaxine may decrease the excretion rate of Pentostatin which could result in a higher serum level.
Clarithromycin	Clarithromycin The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Clarithromycin.
Etodolac	Etodolac Venlafaxine may increase the antiplatelet activities of Etodolac.
Felodipine	Felodipine The metabolism of Felodipine can be decreased when combined with Venlafaxine.
Fosinopril	Fosinopril Venlafaxine may decrease the excretion rate of Fosinopril which could result in a higher serum level.
Nabumetone	Nabumetone Venlafaxine may increase the antiplatelet activities of Nabumetone.
Pravastatin	Pravastatin Venlafaxine may increase the excretion rate of Pravastatin which could result in a lower serum level and potentially a reduction in efficacy.
Simvastatin	Simvastatin The metabolism of Simvastatin can be decreased when combined with Venlafaxine.
Teniposide Injection	Teniposide Injection The metabolism of Teniposide can be decreased when combined with Venlafaxine.
Itraconazole	Itraconazole The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Itraconazole.
Lisinopril	Lisinopril Venlafaxine may decrease the excretion rate of Lisinopril which could result in a higher serum level.
Oxaprozin	Oxaprozin Venlafaxine may increase the antiplatelet activities of Oxaprozin.
Atovaquone	Atovaquone The metabolism of Venlafaxine can be decreased when combined with Atovaquone.
Sotalol	Sotalol The metabolism of Sotalol can be decreased when combined with Venlafaxine.
Bisoprolol	Bisoprolol Venlafaxine may decrease the excretion rate of Bisoprolol which could result in a higher serum level.
Zolpidem	Zolpidem Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin	Doxazosin The metabolism of Venlafaxine can be decreased when combined with Doxazosin.
Isradipine	Isradipine The risk or severity of QTc prolongation can be increased when Isradipine is combined with Venlafaxine.
Omeprazole	Omeprazole The metabolism of Omeprazole can be decreased when combined with Venlafaxine.
Cisapride	Cisapride The metabolism of Cisapride can be decreased when combined with Venlafaxine.
Gabapentin	Gabapentin The risk or severity of adverse effects can be increased when Venlafaxine is combined with Gabapentin.
Fluvastatin	Fluvastatin The metabolism of Venlafaxine can be decreased when combined with Fluvastatin.
Fluvoxamine	Fluvoxamine The metabolism of Venlafaxine can be decreased when combined with Fluvoxamine.
Nefazodone	Nefazodone The metabolism of Nefazodone can be decreased when combined with Venlafaxine.
Lamotrigine	Lamotrigine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Lamotrigine.
Losartan	Losartan The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Losartan.
Valacyclovir	Valacyclovir Valaciclovir may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Tramadol	Tramadol The risk or severity of serotonin syndrome can be increased when Venlafaxine is combined with Tramadol.
Vinorelbine Injection	Vinorelbine Injection The metabolism of Venlafaxine can be decreased when combined with Vinorelbine.
Carboplatin Injection	Carboplatin Injection Carboplatin may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Moexipril	Moexipril The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Moexipril.
Lansoprazole	Lansoprazole The metabolism of Venlafaxine can be decreased when combined with Lansoprazole.
Ifosfamide Injection	Ifosfamide Injection Venlafaxine may decrease the excretion rate of Ifosfamide which could result in a higher serum level.
Nicardipine	Nicardipine The metabolism of Venlafaxine can be decreased when combined with Nicardipine.
Bupropion	Bupropion The risk or severity of seizure can be increased when Venlafaxine is combined with Bupropion.
Ticlopidine	Ticlopidine The metabolism of Ticlopidine can be decreased when combined with Venlafaxine.
Saquinavir	Saquinavir The risk or severity of QTc prolongation can be increased when Saquinavir is combined with Venlafaxine.
Metformin	Metformin The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Metformin.
Dalteparin Injection	Dalteparin Injection Venlafaxine may increase the antiplatelet activities of Dalteparin.
Nisoldipine	Nisoldipine Venlafaxine may decrease the excretion rate of Nisoldipine which could result in a higher serum level.
Lamivudine	Lamivudine Venlafaxine may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole	Riluzole The risk or severity of adverse effects can be increased when Venlafaxine is combined with Riluzole.
Acarbose	Acarbose The risk or severity of hypoglycemia can be increased when Acarbose is combined with Venlafaxine.
Glimepiride	Glimepiride The risk or severity of hypoglycemia can be increased when Glimepiride is combined with Venlafaxine.
Gemcitabine Injection	Gemcitabine Injection Venlafaxine may decrease the excretion rate of Gemcitabine which could result in a higher serum level.
Indinavir	Indinavir The serum concentration of Indinavir can be decreased when it is combined with Venlafaxine.
Ritonavir	Ritonavir The serum concentration of Venlafaxine can be increased when it is combined with Ritonavir.
Cidofovir Injection	Cidofovir Injection Cidofovir may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Meropenem Injection	Meropenem Injection Venlafaxine may decrease the excretion rate of Meropenem which could result in a higher serum level.
Clomipramine	Clomipramine The metabolism of Clomipramine can be decreased when combined with Venlafaxine.
Zafirlukast	Zafirlukast The metabolism of Venlafaxine can be decreased when combined with Zafirlukast.
Fosfomycin	Fosfomycin Venlafaxine may decrease the excretion rate of Fosfomycin which could result in a higher serum level.
Mirtazapine	Mirtazapine Venlafaxine may increase the serotonergic activities of Mirtazapine.
Topiramate	Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Venlafaxine.
Zileuton	Zileuton The metabolism of Zileuton can be decreased when combined with Venlafaxine.
Valsartan	Valsartan The metabolism of Venlafaxine can be decreased when combined with Valsartan.
Insulin Lispro Injection	Insulin Lispro Injection The risk or severity of hypoglycemia can be increased when Insulin lispro is combined with Venlafaxine.
Pramipexole	Pramipexole Venlafaxine may increase the sedative activities of Pramipexole.
Donepezil	Donepezil The metabolism of Donepezil can be decreased when combined with Venlafaxine.
Nelfinavir	Nelfinavir The metabolism of Venlafaxine can be decreased when combined with Nelfinavir.
Azithromycin	Azithromycin The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Azithromycin.
Carvedilol	Carvedilol The metabolism of Carvedilol can be decreased when combined with Venlafaxine.
Nilutamide	Nilutamide The metabolism of Venlafaxine can be decreased when combined with Nilutamide.
Flutamide	Flutamide Venlafaxine may decrease the excretion rate of Flutamide which could result in a higher serum level.
Selegiline	Selegiline The metabolism of Selegiline can be decreased when combined with Venlafaxine.
Bicalutamide	Bicalutamide The metabolism of Venlafaxine can be decreased when combined with Bicalutamide.
Sertraline	Sertraline The metabolism of Sertraline can be decreased when combined with Venlafaxine.
Propafenone	Propafenone The serum concentration of Venlafaxine can be increased when it is combined with Propafenone.
Raloxifene	Raloxifene Venlafaxine may increase the excretion rate of Raloxifene which could result in a lower serum level and potentially a reduction in efficacy.
Irbesartan	Irbesartan The metabolism of Irbesartan can be decreased when combined with Venlafaxine.
Tamsulosin	Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Venlafaxine.
Ropinirole	Ropinirole Venlafaxine may increase the sedative activities of Ropinirole.
Quetiapine	Quetiapine The metabolism of Quetiapine can be decreased when combined with Venlafaxine.
Cefepime Injection	Cefepime Injection Cefepime may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Cefprozil	Cefprozil Cefprozil may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Cefpodoxime	Cefpodoxime Cefpodoxime may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Cetirizine	Cetirizine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Cetirizine.
Paroxetine	Paroxetine The metabolism of Paroxetine can be decreased when combined with Venlafaxine.
Tolcapone	Tolcapone The risk or severity of adverse effects can be increased when Venlafaxine is combined with Tolcapone.
Citalopram	Citalopram The metabolism of Venlafaxine can be decreased when combined with Citalopram.
Capecitabine	Capecitabine The metabolism of Venlafaxine can be decreased when combined with Capecitabine.
Efavirenz	Efavirenz The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Efavirenz.
Abacavir	Abacavir Venlafaxine may decrease the excretion rate of Abacavir which could result in a higher serum level.
Sildenafil	Sildenafil The metabolism of Sildenafil can be decreased when combined with Venlafaxine.
Pioglitazone	Pioglitazone The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Pioglitazone.
Celecoxib	Celecoxib The risk or severity of bleeding can be increased when Celecoxib is combined with Venlafaxine.
Rosiglitazone	Rosiglitazone The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Rosiglitazone.
Tolterodine	Tolterodine The metabolism of Tolterodine can be decreased when combined with Venlafaxine.
Thalidomide	Thalidomide Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Oseltamivir	Oseltamivir Oseltamivir may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Balsalazide	Balsalazide Venlafaxine may increase the antiplatelet activities of Balsalazide.
Nateglinide	Nateglinide The metabolism of Nateglinide can be decreased when combined with Venlafaxine.
Galantamine	Galantamine The metabolism of Galantamine can be decreased when combined with Venlafaxine.
Levetiracetam	Levetiracetam The risk or severity of adverse effects can be increased when Venlafaxine is combined with Levetiracetam.
Rabeprazole	Rabeprazole The metabolism of Rabeprazole can be decreased when combined with Venlafaxine.
Terbinafine	Terbinafine The metabolism of Venlafaxine can be decreased when combined with Terbinafine.