Vincristine Injection

Generic name: Pronounced as (vin kris' teen)
Brand names
  • Oncovin®
  • Vincasar® PFS
  • Vincrex®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 06/15/2013

Vincristine should be administered only into a vein. However, it may leak into surrounding tissue causing severe irritation or damage. Your doctor or nurse will monitor your administration site for this reaction. If you experience any of the following symptoms, call your doctor immediately: pain, itching, redness, swelling, blisters, or sores in the place where the medication was injected.

Vincristine should be given only under the supervision of a doctor with experience in the use of chemotherapy medications.

Vincristine is used in combination with other chemotherapy drugs to treat certain types of leukemia (cancer of the white blood cells), including acute myeloid leukemia (AML, ANLL) and acute lymphoblastic leukemia (ALL), Hodgkin's lymphoma (Hodgkin's disease), and non-Hodgkin's lymphoma (types of cancer that begin in a type of white blood cells that normally fights infection). Vincristine is also used in combination with other chemotherapy drugs to treat Wilms tumor (a type of kidney cancer that occurs in children), neuroblastoma (a cancer that begins in nerve cells and occurs mainly in children), and rhabdomyosarcoma (cancer that forms in muscles in children). Vincristine is in a class of medications called vinca alkaloids. It works by slowing or stopping the growth of cancer cells in your body.

Vincristine comes as a solution (liquid) to be injected intravenously (into a vein) by a doctor or nurse in a medical facility. It is usually given once a week. The length of treatment depends on the types of drugs you are taking, how well your body responds to them, and the type of cancer you have.

Your doctor may need to delay your treatment or change your dose if you experience certain side effects. It is important for you to tell your doctor how you are feeling during your treatment with vincristine injection.

Your doctor may tell you to take a stool softener or laxative to help prevent constipation during your treatment with vincristine injection.

Vincristine is also sometimes used to treat certain types of brain tumors, certain types of lung cancer, multiple myeloma (a type of cancer of the bone marrow), chronic lymphocytic leukemia (CLL; a type of cancer of the white blood cells), Kaposi's sarcoma (a type of cancer that causes abnormal tissue to grow on different parts of the body) related to acquired immunodeficiency syndrome (AIDS), Ewings sarcoma (a type of cancer in bones or muscle), and gestational trophoblastic tumors (a type of tumor that forms inside a woman's uterus while she is pregnant). Vincristine is also sometimes used to treat thrombotic thrombocytopenic purpura (TPP; a blood disorder that causes blood clots to form in small blood vessels in the body). Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before receiving vincristine,

  • tell your doctor and pharmacist if you are allergic to vincristine, any other medications, or any of the ingredients in vincristine injection. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: aprepitant (Emend); carbamazepine (Tegretol); certain antifungals such as itraconazole (Sporanox), ketoconazole (Nizoral), voriconazole (Vfend), and posaconazole (Noxafil); clarithromycin (Biaxin, in Prevpac); darifenacin (Enablex); dexamethasone (Decadron); fesoterodine (Toviaz); HIV protease inhibitors including atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), and saquinavir (Invirase); nefazodone; oxybutynin (Ditropan, Ditropan XL, Oxytrol); phenobarbital; phenytoin (Dilantin); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane); rifapentine (Priftin); solifenacin (Vesicare); telithromycin (Ketek); trospium (Sanctura); or tolterodine (Detrol, Detrol LA). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor what herbal products you are taking, especially St. John's wort.

  • tell your doctor if you have or have ever had a disorder that affects your nerves. Your doctor may not want you to receive vincristine injection.

  • tell your doctor if you are having or have ever had radiation (x-ray) therapy, if you have an infection, or if you have or have ever had lung or liver disease.

  • you should know that vincristine may interfere with the normal menstrual cycle (period) in women and may temporarily or permanently stop sperm production in men. Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. You should not become pregnant or breastfeed while you are receiving vincristine injection. If you become pregnant while receiving vincristine injection, call your doctor. Vincristine may harm the fetus.

Unless your doctor tells you otherwise, continue your normal diet.

  • Vincristine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • nausea

    • vomiting

    • sores in the mouth and throat

    • loss of appetite or weight

    • stomach pain

    • diarrhea

    • headache

    • hair loss

  • Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, and call your doctor immediately or get emergency medical treatment:

    • hives

    • rash

    • itching

    • difficulty breathing or swallowing

    • constipation

    • increased or decreased urination

    • swelling of the face, arms, hands, feet, ankles, or lower legs

    • unusual bleeding or bruising

    • unusual tiredness or weakness

    • pain, numbness, burning, or tingling in the hands or feet

    • difficulty walking or unsteady walking

    • muscle or joint pain

    • sudden changes in vision, including loss of vision

    • hearing loss

    • dizziness

    • loss of the ability to move muscles and to feel a part of the body

    • hoarseness or loss of ability to speak loudly

    • seizures

    • jaw pain

    • fever, sore throat, chills, or other signs of infection

  • Vincristine may increase the risk that you will develop other cancers. Talk to your doctor about the risks of receiving vincristine injection.

  • Vincristine may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

  • seizures

  • severe constipation

  • stomach pain

  • unusual bleeding or bruising

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to vincristine.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • LCR
  • Leurocristine Sulfate
  • VCR

Drug Interaction
Repaglinide Repaglinide Vincristine may decrease the excretion rate of Repaglinide which could result in a higher serum level.
Montelukast Montelukast The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Montelukast is combined with Vincristine.
Leflunomide Leflunomide The risk or severity of adverse effects can be increased when Vincristine is combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Vincristine can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Vincristine can be decreased when combined with Nevirapine.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Vincristine.
Alendronate Alendronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Alendronic acid.
Cilostazol Cilostazol The metabolism of Cilostazol can be decreased when combined with Vincristine.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Vincristine.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The excretion of Vincristine can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The excretion of Conjugated estrogens can be decreased when combined with Vincristine.
Fenofibrate Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Vincristine.
Methylergonovine Methylergonovine The metabolism of Vincristine can be decreased when combined with Methylergometrine.
Mycophenolate Mycophenolate The risk or severity of adverse effects can be increased when Vincristine is combined with Mycophenolic acid.
Nafarelin Nafarelin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Nafarelin.
Paregoric Paregoric The serum concentration of Vincristine can be increased when it is combined with Morphine.
Prednisone Prednisone The risk or severity of adverse effects can be increased when Prednisone is combined with Vincristine.
Ranitidine Ranitidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Ranitidine.
Reserpine Reserpine The excretion of Vincristine can be decreased when combined with Reserpine.
Sumatriptan Sumatriptan The excretion of Sumatriptan can be decreased when combined with Vincristine.
Tacrolimus Tacrolimus Tacrolimus may increase the immunosuppressive activities of Vincristine.
Triamcinolone Triamcinolone The metabolism of Triamcinolone can be increased when combined with Vincristine.
Doxycycline Injection Doxycycline Injection The metabolism of Vincristine can be decreased when combined with Doxycycline.
Fluconazole Injection Fluconazole Injection The excretion of Vincristine can be decreased when combined with Fluconazole.
Interferon Beta-1b Injection Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Vincristine.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Vincristine.
Meperidine Injection Meperidine Injection The metabolism of Vincristine can be increased when combined with Meperidine.
Methylprednisolone Injection Methylprednisolone Injection The metabolism of Methylprednisolone can be increased when combined with Vincristine.
Metoclopramide Injection Metoclopramide Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Metoclopramide.
Metronidazole Injection Metronidazole Injection The metabolism of Metronidazole can be decreased when combined with Vincristine.
Morphine Injection Morphine Injection The serum concentration of Vincristine can be increased when it is combined with Morphine.
Pamidronate Injection Pamidronate Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Pamidronic acid is combined with Vincristine.
Zidovudine Injection Zidovudine Injection The risk or severity of adverse effects can be increased when Zidovudine is combined with Vincristine.
Cyclosporine Cyclosporine Vincristine may increase the immunosuppressive activities of Cyclosporine.
Ondansetron Ondansetron The metabolism of Ondansetron can be decreased when combined with Vincristine.
Torsemide Torsemide The excretion of Torasemide can be decreased when combined with Vincristine.
Eprosartan Eprosartan The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Eprosartan.
Hydroxychloroquine Hydroxychloroquine The risk or severity of adverse effects can be increased when Vincristine is combined with Hydroxychloroquine.
Orlistat Orlistat The metabolism of Vincristine can be increased when combined with Orlistat.
Oxcarbazepine Oxcarbazepine The metabolism of Vincristine can be increased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Vincristine which could result in a higher serum level.
Risedronate Risedronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Risedronic acid.
Telmisartan Telmisartan Telmisartan may decrease the excretion rate of Vincristine which could result in a higher serum level.
Temozolomide Temozolomide The risk or severity of adverse effects can be increased when Vincristine is combined with Temozolomide.
Zaleplon Zaleplon The metabolism of Zaleplon can be decreased when combined with Vincristine.
Anakinra Anakinra The metabolism of Vincristine can be increased when combined with Anakinra.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Vincristine is combined with Linezolid.
Trimipramine Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Vincristine.
Etanercept Injection Etanercept Injection The metabolism of Vincristine can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Vincristine can be increased when combined with Modafinil.
Tenofovir Tenofovir The metabolism of Vincristine can be decreased when combined with Tenofovir.
Sirolimus Sirolimus The metabolism of Sirolimus can be decreased when combined with Vincristine.
Dutasteride Dutasteride The metabolism of Dutasteride can be decreased when combined with Vincristine.
Epinephrine Injection Epinephrine Injection The metabolism of Vincristine can be decreased when combined with Epinephrine.
Epirubicin Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with Vincristine.
Eplerenone Eplerenone The metabolism of Eplerenone can be decreased when combined with Vincristine.
Olmesartan Olmesartan Olmesartan may decrease the excretion rate of Vincristine which could result in a higher serum level.
Zonisamide Zonisamide The excretion of Vincristine can be decreased when combined with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Vincristine can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Vincristine.
Ezetimibe Ezetimibe Vincristine may decrease the excretion rate of Ezetimibe which could result in a higher serum level.
Glatiramer Injection Glatiramer Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Glatiramer.
Atazanavir Atazanavir The metabolism of Atazanavir can be decreased when combined with Vincristine.
Mefloquine Mefloquine The metabolism of Vincristine can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Vincristine.
Vardenafil Vardenafil The excretion of Vardenafil can be decreased when combined with Vincristine.
Aprepitant Aprepitant The metabolism of Vincristine can be decreased when combined with Aprepitant.
Tegaserod Tegaserod The serum concentration of Vincristine can be increased when it is combined with Tegaserod.
Tadalafil Tadalafil The metabolism of Tadalafil can be decreased when combined with Vincristine.
Progesterone Progesterone The metabolism of Vincristine can be increased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Vincristine.
Darbepoetin Alfa Injection Darbepoetin Alfa Injection The risk or severity of peripheral neuropathy can be increased when Darbepoetin alfa is combined with Vincristine.
Infliximab Injection Infliximab Injection The metabolism of Vincristine can be increased when combined with Infliximab.
Protriptyline Protriptyline Protriptyline may increase the neurotoxic activities of Vincristine.
Rifaximin Rifaximin The metabolism of Vincristine can be increased when combined with Rifaximin.
Duloxetine Duloxetine The metabolism of Vincristine can be decreased when combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Norethisterone can be decreased when combined with Vincristine.
Tinidazole Tinidazole Vincristine may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Bosentan Bosentan The metabolism of Vincristine can be increased when combined with Bosentan.
Natalizumab Injection Natalizumab Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Natalizumab.
Erlotinib Erlotinib The metabolism of Vincristine can be decreased when combined with Erlotinib.
Ganciclovir Ganciclovir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Ganciclovir.
Voriconazole Voriconazole The metabolism of Vincristine can be decreased when combined with Voriconazole.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Vincristine.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Vincristine.
Ibandronate Ibandronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Ibandronate.
Fentanyl Fentanyl The metabolism of Fentanyl can be decreased when combined with Vincristine.
Deferasirox Deferasirox The metabolism of Vincristine can be increased when combined with Deferasirox.
Tipranavir Tipranavir The serum concentration of Vincristine can be decreased when it is combined with Tipranavir.
Felbamate Felbamate The metabolism of Vincristine can be increased when combined with Felbamate.
Ranolazine Ranolazine The serum concentration of Vincristine can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Vincristine can be increased when combined with Abatacept.
Imatinib Imatinib The metabolism of Vincristine can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin The serum concentration of Vincristine can be increased when it is combined with Sitagliptin.
Bevacizumab Injection Bevacizumab Injection The risk or severity of adverse effects can be increased when Bevacizumab is combined with Vincristine.
Gefitinib Gefitinib The metabolism of Vincristine can be decreased when combined with Gefitinib.
Paliperidone Paliperidone The excretion of Vincristine can be decreased when combined with Paliperidone.
Bortezomib Bortezomib The risk or severity of adverse effects can be increased when Bortezomib is combined with Vincristine.
Clofarabine Injection Clofarabine Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Clofarabine.
Hepatitis B Vaccine Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Vincristine.
Influenza Vaccine, Inactivated or Recombinant Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Vincristine.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Vincristine.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Vincristine.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Vincristine.
Posaconazole Posaconazole The metabolism of Vincristine can be decreased when combined with Posaconazole.
Primaquine Primaquine The metabolism of Vincristine can be decreased when combined with Primaquine.
Rituximab Injection Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Vincristine.
Bismuth Subsalicylate Bismuth Subsalicylate Vincristine may increase the neurotoxic activities of Bismuth subsalicylate.
Darunavir Darunavir The serum concentration of Vincristine can be increased when it is combined with Darunavir.
Pemetrexed Injection Pemetrexed Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Pemetrexed.
Vorinostat Vorinostat The risk or severity of adverse effects can be increased when Vincristine is combined with Vorinostat.
Sorafenib Sorafenib The excretion of Vincristine can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Vincristine can be decreased when combined with Sunitinib.
Dronabinol Dronabinol Dronabinol may decrease the excretion rate of Vincristine which could result in a higher serum level.
Lapatinib Lapatinib The excretion of Vincristine can be decreased when combined with Lapatinib.
Pegfilgrastim Injection Pegfilgrastim Injection The risk or severity of peripheral neuropathy can be increased when Pegfilgrastim is combined with Vincristine.
Dasatinib Dasatinib The metabolism of Vincristine can be decreased when combined with Dasatinib.
Armodafinil Armodafinil The metabolism of Vincristine can be increased when combined with Armodafinil.
Azacitidine Injection Azacitidine Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Azacitidine.
Ivermectin Ivermectin The metabolism of Ivermectin can be increased when combined with Vincristine.
Temsirolimus Temsirolimus The excretion of Vincristine can be decreased when combined with Temsirolimus.
Nelarabine Injection Nelarabine Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Nelarabine.
Lenalidomide Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with Vincristine.
Nilotinib Nilotinib The excretion of Vincristine can be decreased when combined with Nilotinib.
Toremifene Toremifene The excretion of Vincristine can be decreased when combined with Toremifene.
Raltegravir Raltegravir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Raltegravir.
Bexarotene Bexarotene The metabolism of Vincristine can be increased when combined with Bexarotene.
Budesonide Budesonide The metabolism of Budesonide can be increased when combined with Vincristine.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Vincristine can be decreased when combined with Chloramphenicol.
Decitabine Injection Decitabine Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Decitabine.
Etravirine Etravirine The serum concentration of Vincristine can be decreased when it is combined with Etravirine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Arsenic trioxide.
Mitoxantrone Injection Mitoxantrone Injection The metabolism of Mitoxantrone can be decreased when combined with Vincristine.
Desvenlafaxine Desvenlafaxine The metabolism of Vincristine can be decreased when combined with Desvenlafaxine.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Vincristine.
Bendamustine Injection Bendamustine Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Bendamustine.
Pilocarpine Pilocarpine The metabolism of Vincristine can be decreased when combined with Pilocarpine.
Certolizumab Injection Certolizumab Injection The metabolism of Vincristine can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Ixabepilone.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Vincristine.
Daptomycin Injection Daptomycin Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Daptomycin is combined with Vincristine.
Estramustine Estramustine The risk or severity of adverse effects can be increased when Vincristine is combined with Estramustine.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Vincristine.
Mitotane Mitotane The metabolism of Vincristine can be increased when combined with Mitotane.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Vincristine.
Rufinamide Rufinamide The metabolism of Vincristine can be increased when combined with Rufinamide.
Silodosin Silodosin The serum concentration of Vincristine can be increased when it is combined with Silodosin.
Midazolam Midazolam The metabolism of Midazolam can be decreased when combined with Vincristine.
Naltrexone Injection Naltrexone Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Naltrexone.
Romiplostim Injection Romiplostim Injection The risk or severity of peripheral neuropathy can be increased when Romiplostim is combined with Vincristine.
Dexrazoxane Injection Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Vincristine.
Eltrombopag Eltrombopag Eltrombopag may decrease the excretion rate of Vincristine which could result in a higher serum level.
Ibritumomab Injection Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Vincristine.
Milnacipran Milnacipran The metabolism of Vincristine can be decreased when combined with Milnacipran.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Vincristine.
Lacosamide Lacosamide The metabolism of Vincristine can be decreased when combined with Lacosamide.
Everolimus Everolimus The risk or severity of adverse effects can be increased when Everolimus is combined with Vincristine.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The serum concentration of Vincristine can be increased when it is combined with Tolvaptan.
Dronedarone Dronedarone The excretion of Vincristine can be decreased when combined with Dronedarone.
Pralatrexate Injection Pralatrexate Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Pralatrexate.
Saxagliptin Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Vincristine.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Vincristine.
Topotecan Topotecan The metabolism of Topotecan can be increased when combined with Vincristine.
Golimumab Injection Golimumab Injection The metabolism of Vincristine can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Vincristine can be decreased when combined with Pazopanib.
Asenapine Asenapine Vincristine may increase the neurotoxic activities of Asenapine.
Pitavastatin Pitavastatin Vincristine may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Albendazole Albendazole The metabolism of Vincristine can be decreased when combined with Albendazole.
Levonorgestrel Levonorgestrel The metabolism of Vincristine can be decreased when combined with Levonorgestrel.
Denosumab Injection Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Vincristine.
Tocilizumab Injection Tocilizumab Injection The metabolism of Vincristine can be increased when combined with Tocilizumab.
Fingolimod Fingolimod Vincristine may increase the immunosuppressive activities of Fingolimod.
Eribulin Injection Eribulin Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Eribulin.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Vincristine can be decreased when combined with Cabazitaxel.
Lurasidone Lurasidone Vincristine may increase the neurotoxic activities of Lurasidone.
Acetaminophen Injection Acetaminophen Injection The metabolism of Vincristine can be increased when combined with Acetaminophen.
Denileukin Diftitox Injection Denileukin Diftitox Injection The metabolism of Vincristine can be decreased when combined with Aldesleukin.
Sipuleucel-T Injection Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Vincristine.
Belimumab Injection Belimumab Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Belimumab.
Busulfan Injection Busulfan Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Busulfan.
Roflumilast Roflumilast Roflumilast may increase the immunosuppressive activities of Vincristine.
Linagliptin Linagliptin The excretion of Vincristine can be decreased when combined with Linagliptin.
Rilpivirine Rilpivirine The metabolism of Vincristine can be decreased when combined with Rilpivirine.
Telaprevir Telaprevir The excretion of Vincristine can be decreased when combined with Glecaprevir.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Vincristine can be increased when combined with Cyclophosphamide.
Rivaroxaban Rivaroxaban The metabolism of Rivaroxaban can be decreased when combined with Vincristine.
Ticagrelor Ticagrelor The excretion of Vincristine can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be decreased when combined with Vincristine.
Ruxolitinib Ruxolitinib The risk or severity of adverse effects can be increased when Vincristine is combined with Ruxolitinib.
Vandetanib Vandetanib The excretion of Vincristine can be decreased when combined with Vandetanib.
Clobazam Clobazam The metabolism of Vincristine can be increased when combined with Clobazam.
Vemurafenib Vemurafenib The serum concentration of Vincristine can be increased when it is combined with Vemurafenib.
Vismodegib Vismodegib Vismodegib may decrease the excretion rate of Vincristine which could result in a higher serum level.
Belatacept Injection Belatacept Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Belatacept.
Ivacaftor Ivacaftor The excretion of Vincristine can be decreased when combined with Ivacaftor.
Basiliximab Injection Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Vincristine.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Vincristine.
Crizotinib Crizotinib The metabolism of Vincristine can be decreased when combined with Crizotinib.
Melphalan Injection Melphalan Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Melphalan.
Cabergoline Cabergoline The metabolism of Vincristine can be decreased when combined with Cabergoline.
Naloxone Injection Naloxone Injection The metabolism of Vincristine can be decreased when combined with Naloxone.
Ambrisentan Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Vincristine.
Eculizumab Injection Eculizumab Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Eculizumab.
Pertuzumab Injection Pertuzumab Injection The risk or severity of cardiotoxicity can be increased when Vincristine is combined with Pertuzumab.
Carfilzomib Injection Carfilzomib Injection The excretion of Carfilzomib can be decreased when combined with Vincristine.
Iloprost Iloprost The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Iloprost.
Enzalutamide Enzalutamide The excretion of Vincristine can be decreased when combined with Enzalutamide.
Mirabegron Mirabegron The excretion of Vincristine can be decreased when combined with Mirabegron.
Regorafenib Regorafenib The excretion of Vincristine can be decreased when combined with Regorafenib.
Bosutinib Bosutinib The metabolism of Bosutinib can be decreased when combined with Vincristine.
Corticotropin, Repository Injection Corticotropin, Repository Injection The metabolism of Corticotropin can be increased when combined with Vincristine.
Teriflunomide Teriflunomide The risk or severity of adverse effects can be increased when Vincristine is combined with Teriflunomide.
Tofacitinib Tofacitinib Vincristine may increase the immunosuppressive activities of Tofacitinib.
Dimethyl Fumarate Dimethyl Fumarate The risk or severity of adverse effects can be increased when Vincristine is combined with Dimethyl fumarate.
Ponatinib Ponatinib The excretion of Vincristine can be decreased when combined with Ponatinib.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Vincristine is combined with Pomalidomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Vincristine.
Apixaban Apixaban The metabolism of Vincristine can be decreased when combined with Apixaban.
Canagliflozin Canagliflozin The excretion of Vincristine can be decreased when combined with Canagliflozin.
Dabrafenib Dabrafenib The metabolism of Vincristine can be increased when combined with Dabrafenib.
Trametinib Trametinib The metabolism of Vincristine can be increased when combined with Trametinib.
Dolutegravir Dolutegravir The serum concentration of Vincristine can be increased when it is combined with Dolutegravir.
Afatinib Afatinib The excretion of Vincristine can be decreased when combined with Afatinib.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Vincristine.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Vincristine.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Vincristine.
Lomitapide Lomitapide The excretion of Vincristine can be decreased when combined with Lomitapide.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Obinutuzumab.
Simeprevir Simeprevir The excretion of Vincristine can be decreased when combined with Simeprevir.
Sofosbuvir Sofosbuvir The serum concentration of Vincristine can be increased when it is combined with Sofosbuvir.
Apremilast Apremilast The metabolism of Vincristine can be increased when combined with Apremilast.
Ceritinib Ceritinib The metabolism of Vincristine can be decreased when combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Vincristine can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The metabolism of Vincristine can be increased when combined with Eslicarbazepine.
Vedolizumab Injection Vedolizumab Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Vedolizumab.
Belinostat Injection Belinostat Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Belinostat.
Idelalisib Idelalisib The risk or severity of adverse effects can be increased when Idelalisib is combined with Vincristine.
Testosterone Injection Testosterone Injection The metabolism of Testosterone can be increased when combined with Vincristine.
Oritavancin Injection Oritavancin Injection The metabolism of Vincristine can be increased when combined with Oritavancin.
Vorapaxar Vorapaxar The excretion of Vincristine can be decreased when combined with Vorapaxar.
Suvorexant Suvorexant The excretion of Vincristine can be decreased when combined with Suvorexant.
Edoxaban Edoxaban The serum concentration of Vincristine can be increased when it is combined with Edoxaban.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Peginterferon beta-1a.
Olaparib Olaparib The metabolism of Olaparib can be decreased when combined with Vincristine.
Blinatumomab Injection Blinatumomab Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Blinatumomab.
Caspofungin Injection Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Vincristine.
Tasimelteon Tasimelteon The metabolism of Vincristine can be decreased when combined with Tasimelteon.
Lanreotide Injection Lanreotide Injection The metabolism of Vincristine can be decreased when combined with Lanreotide.
Pirfenidone Pirfenidone The risk or severity of adverse effects can be increased when Vincristine is combined with Pirfenidone.
Nintedanib Nintedanib The metabolism of Vincristine can be decreased when combined with Nintedanib.
Secukinumab Injection Secukinumab Injection The metabolism of Vincristine can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Risperidone can be decreased when combined with Vincristine.
Palbociclib Palbociclib The excretion of Vincristine can be decreased when combined with Palbociclib.
Lenvatinib Lenvatinib The metabolism of Vincristine can be increased when combined with Lenvatinib.
Panobinostat Panobinostat The risk or severity of adverse effects can be increased when Vincristine is combined with Panobinostat.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The serum concentration of Vincristine can be increased when it is combined with Haloperidol.
Deoxycholic Acid Injection Deoxycholic Acid Injection Deoxycholic acid may increase the excretion rate of Vincristine which could result in a lower serum level and potentially a reduction in efficacy.
Isavuconazonium Injection Isavuconazonium Injection The excretion of Vincristine can be decreased when combined with Isavuconazonium.
Flibanserin Flibanserin The excretion of Vincristine can be decreased when combined with Flibanserin.
Rolapitant Rolapitant The excretion of Vincristine can be decreased when combined with Rolapitant.
Prednisolone Prednisolone The metabolism of Prednisolone can be increased when combined with Vincristine.
Daclatasvir Daclatasvir The excretion of Vincristine can be decreased when combined with Daclatasvir.
Brexpiprazole Brexpiprazole Vincristine may increase the neurotoxic activities of Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The metabolism of Vincristine can be decreased when combined with Ziprasidone.
Cariprazine Cariprazine Vincristine may increase the neurotoxic activities of Cariprazine.
Eluxadoline Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Vincristine.
Cobimetinib Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Vincristine.
Mepolizumab Injection Mepolizumab Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Mepolizumab.
Trabectedin Injection Trabectedin Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Trabectedin.
Osimertinib Osimertinib The metabolism of Vincristine can be increased when combined with Osimertinib.
Alectinib Alectinib Alectinib may decrease the excretion rate of Vincristine which could result in a higher serum level.
Rifapentine Rifapentine The metabolism of Vincristine can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Vincristine can be increased when combined with Lesinurad.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The metabolism of Amphotericin B can be decreased when combined with Vincristine.
Dexamethasone Injection Dexamethasone Injection The metabolism of Vincristine can be increased when combined with Dexamethasone.
Ixekizumab Injection Ixekizumab Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Ixekizumab.
Venetoclax Venetoclax The excretion of Vincristine can be decreased when combined with Venetoclax.
Cobicistat Cobicistat The excretion of Vincristine can be decreased when combined with Cobicistat.
Selexipag Selexipag The serum concentration of Selexipag can be increased when it is combined with Vincristine.
Pimavanserin Pimavanserin Vincristine may increase the neurotoxic activities of Pimavanserin.
Rucaparib Rucaparib The excretion of Vincristine can be decreased when combined with Rucaparib.
Ribociclib Ribociclib The metabolism of Vincristine can be decreased when combined with Ribociclib.
Brodalumab Injection Brodalumab Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Brodalumab.
Brigatinib Brigatinib The metabolism of Vincristine can be increased when combined with Brigatinib.
Doxepin (Insomnia) Doxepin (Insomnia) Vincristine may increase the neurotoxic activities of Doxepin.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Vincristine.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Vincristine.
Deflazacort Deflazacort The metabolism of Deflazacort can be increased when combined with Vincristine.
Safinamide Safinamide The metabolism of Vincristine can be decreased when combined with Safinamide.
Ocrelizumab Injection Ocrelizumab Injection Ocrelizumab may increase the immunosuppressive activities of Vincristine.
Sarilumab Injection Sarilumab Injection The metabolism of Sarilumab can be increased when combined with Vincristine.
Midostaurin Midostaurin The metabolism of Vincristine can be increased when combined with Midostaurin.
Neratinib Neratinib The excretion of Vincristine can be decreased when combined with Neratinib.
Guselkumab Injection Guselkumab Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Guselkumab.
Enasidenib Enasidenib The excretion of Vincristine can be decreased when combined with Enasidenib.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Vincristine can be increased when it is combined with Inotuzumab ozogamicin.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Vincristine can be increased when combined with Fosaprepitant.
Copanlisib Injection Copanlisib Injection The metabolism of Vincristine can be decreased when combined with Copanlisib.
Abemaciclib Abemaciclib Abemaciclib may decrease the excretion rate of Vincristine which could result in a higher serum level.
Betrixaban Betrixaban The serum concentration of Vincristine can be increased when it is combined with Betrixaban.
Acalabrutinib Acalabrutinib The metabolism of Vincristine can be decreased when combined with Acalabrutinib.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Vincristine.
Letermovir Letermovir The metabolism of Vincristine can be decreased when combined with Letermovir.
Ertugliflozin Ertugliflozin The serum concentration of Vincristine can be increased when it is combined with Ertugliflozin.
Buprenorphine Injection Buprenorphine Injection The metabolism of Vincristine can be decreased when combined with Buprenorphine.
Apalutamide Apalutamide The serum concentration of Vincristine can be decreased when it is combined with Apalutamide.
Penicillamine Penicillamine The risk or severity of adverse effects can be increased when Vincristine is combined with Penicillamine.
Fostamatinib Fostamatinib The metabolism of Vincristine can be decreased when combined with Fostamatinib.
Avatrombopag Avatrombopag Avatrombopag may decrease the excretion rate of Vincristine which could result in a higher serum level.
Baricitinib Baricitinib The risk or severity of adverse effects can be increased when Vincristine is combined with Baricitinib.
Eliglustat Eliglustat The serum concentration of Vincristine can be increased when it is combined with Eliglustat.
Binimetinib Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Vincristine.
Ivosidenib Ivosidenib The excretion of Vincristine can be decreased when combined with Ivosidenib.
Lusutrombopag Lusutrombopag The serum concentration of Vincristine can be increased when it is combined with Lusutrombopag.
Elagolix Elagolix The excretion of Elagolix can be decreased when combined with Vincristine.
Doravirine Doravirine The metabolism of Doravirine can be decreased when combined with Vincristine.
Cannabidiol Cannabidiol The metabolism of Vincristine can be decreased when combined with Cannabidiol.
Dacomitinib Dacomitinib The excretion of Vincristine can be decreased when combined with Dacomitinib.
Duvelisib Duvelisib The metabolism of Vincristine can be decreased when combined with Duvelisib.
Omadacycline Omadacycline The serum concentration of Vincristine can be increased when it is combined with Omadacycline.
Sarecycline Sarecycline The excretion of Vincristine can be decreased when combined with Sarecycline.
Stiripentol Stiripentol The metabolism of Vincristine can be decreased when combined with Stiripentol.
Talazoparib Talazoparib The serum concentration of Vincristine can be increased when it is combined with Talazoparib.
Gilteritinib Gilteritinib The metabolism of Vincristine can be decreased when combined with Gilteritinib.
Glasdegib Glasdegib The excretion of Vincristine can be decreased when combined with Glasdegib.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Vincristine.
Larotrectinib Larotrectinib The serum concentration of Vincristine can be increased when it is combined with Larotrectinib.
Methoxy Polyethylene Glycol-Epoetin Beta Injection Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of peripheral neuropathy can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Vincristine.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Vincristine.
Rifamycin Rifamycin The excretion of Vincristine can be decreased when combined with Rifamycin.
Prucalopride Prucalopride The metabolism of Vincristine can be decreased when combined with Prucalopride.
Ravulizumab-cwvz Injection Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Ravulizumab.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Vincristine can be increased when combined with Emapalumab.
Siponimod Siponimod The risk or severity of adverse effects can be increased when Vincristine is combined with Siponimod.
Erdafitinib Erdafitinib The serum concentration of Vincristine can be increased when it is combined with Erdafitinib.
Risankizumab-rzaa Injection Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Risankizumab.
Alpelisib Alpelisib The metabolism of Vincristine can be increased when combined with Alpelisib.
Cladribine Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Vincristine.
Darolutamide Darolutamide Darolutamide may decrease the excretion rate of Vincristine which could result in a higher serum level.
Triclabendazole Triclabendazole The metabolism of Vincristine can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The excretion of Entrectinib can be decreased when combined with Vincristine.
Istradefylline Istradefylline The excretion of Istradefylline can be decreased when combined with Vincristine.
Pitolisant Pitolisant The serum concentration of Vincristine can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The excretion of Vincristine can be decreased when combined with Fedratinib.
Lefamulin Lefamulin The serum concentration of Vincristine can be increased when it is combined with Lefamulin.
Phenytoin Injection Phenytoin Injection The serum concentration of Vincristine can be decreased when it is combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The serum concentration of Vincristine can be decreased when it is combined with Fosphenytoin.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Vincristine can be increased when it is combined with Enfortumab vedotin.
Voxelotor Voxelotor The serum concentration of Vincristine can be increased when it is combined with Voxelotor.
Lasmiditan Lasmiditan The serum concentration of Vincristine can be increased when it is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Vincristine can be increased when it is combined with Ubrogepant.
Tazemetostat Tazemetostat The metabolism of Vincristine can be decreased when combined with Tazemetostat.
Bempedoic Acid Bempedoic Acid The excretion of Bempedoic acid can be decreased when combined with Vincristine.
Cenobamate Cenobamate The serum concentration of Vincristine can be decreased when it is combined with Cenobamate.
Ozanimod Ozanimod The risk or severity of adverse effects can be increased when Vincristine is combined with Ozanimod.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Vincristine.
Rimegepant Rimegepant The serum concentration of Vincristine can be increased when it is combined with Rimegepant.
Tucatinib Tucatinib Tucatinib may decrease the excretion rate of Vincristine which could result in a higher serum level.
Remdesivir Injection Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Vincristine.
Ripretinib Ripretinib The excretion of Vincristine can be decreased when combined with Ripretinib.
Capmatinib Capmatinib The serum concentration of Vincristine can be increased when it is combined with Capmatinib.
Lemborexant Lemborexant The metabolism of Lemborexant can be decreased when combined with Vincristine.
Fostemsavir Fostemsavir Fostemsavir may decrease the excretion rate of Vincristine which could result in a higher serum level.
Octreotide Octreotide The serum concentration of Vincristine can be increased when it is combined with Octreotide.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection Vincristine may decrease the excretion rate of Belantamab mafodotin which could result in a higher serum level.
Pralsetinib Pralsetinib The excretion of Vincristine can be decreased when combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Vincristine can be decreased when it is combined with Satralizumab.
Naxitamab-gqgk Injection Naxitamab-gqgk Injection Vincristine may increase the neurotoxic activities of Naxitamab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Vincristine can be decreased when combined with Drospirenone.
Vitamin E (Alpha-Tocopherol) Vitamin E (Alpha-Tocopherol) The metabolism of Vincristine can be increased when combined with Vitamin E.
Indomethacin Indomethacin The risk or severity of adverse effects can be increased when Indomethacin is combined with Vincristine.
Naproxen Naproxen Vincristine may decrease the excretion rate of Naproxen which could result in a higher serum level.
Trazodone Trazodone The serum concentration of Vincristine can be decreased when it is combined with Trazodone.
Isotretinoin Isotretinoin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Isotretinoin.
Hydroxyurea Hydroxyurea The risk or severity of adverse effects can be increased when Vincristine is combined with Hydroxyurea.
Floxuridine Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Vincristine.
Phenobarbital Phenobarbital The metabolism of Vincristine can be increased when combined with Phenobarbital.
Methotrexate Injection Methotrexate Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Methotrexate.
Primidone Primidone The metabolism of Vincristine can be increased when combined with Primidone.
Chlorpromazine Chlorpromazine The metabolism of Vincristine can be increased when combined with Chlorpromazine.
Diazepam Diazepam The metabolism of Diazepam can be decreased when combined with Vincristine.
Lorazepam Lorazepam The metabolism of Vincristine can be decreased when combined with Lorazepam.
Carmustine Carmustine The risk or severity of adverse effects can be increased when Carmustine is combined with Vincristine.
Bromocriptine Bromocriptine The metabolism of Vincristine can be decreased when combined with Bromocriptine.
Tranylcypromine Tranylcypromine The metabolism of Vincristine can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Vincristine can be decreased when combined with Phenelzine.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Vincristine is combined with Procarbazine.
Tetracycline Tetracycline The metabolism of Vincristine can be decreased when combined with Tetracycline.
Thioguanine Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Vincristine.
Minocycline Minocycline The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Minocycline.
Prochlorperazine Prochlorperazine The metabolism of Vincristine can be decreased when combined with Prochlorperazine.
Thioridazine Thioridazine Vincristine may increase the neurotoxic activities of Thioridazine.
Trifluoperazine Trifluoperazine Vincristine may increase the neurotoxic activities of Trifluoperazine.
Bleomycin Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Vincristine.
Dapsone Dapsone The metabolism of Vincristine can be decreased when combined with Dapsone.
Oxycodone Oxycodone The metabolism of Vincristine can be decreased when combined with Oxycodone.
Methadone Methadone The metabolism of Vincristine can be increased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Oxybutynin can be decreased when combined with Vincristine.
Orphenadrine Orphenadrine The metabolism of Vincristine can be decreased when combined with Orphenadrine.
Perphenazine Perphenazine Vincristine may increase the neurotoxic activities of Perphenazine.
Azathioprine Azathioprine The risk or severity of adverse effects can be increased when Vincristine is combined with Azathioprine.
Fluphenazine Fluphenazine Vincristine may increase the neurotoxic activities of Fluphenazine.
Phentermine Phentermine The metabolism of Vincristine can be decreased when combined with Phentermine.
Amoxapine Amoxapine Vincristine may increase the neurotoxic activities of Amoxapine.
Sulfasalazine Sulfasalazine The risk or severity of adverse effects can be increased when Vincristine is combined with Sulfasalazine.
Hydrocortisone Hydrocortisone The metabolism of Hydrocortisone can be increased when combined with Vincristine.
Lomustine Lomustine The risk or severity of adverse effects can be increased when Vincristine is combined with Lomustine.
Doxorubicin Doxorubicin The metabolism of Doxorubicin can be decreased when combined with Vincristine.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Vincristine is combined with Cytarabine.
Mechlorethamine Mechlorethamine The risk or severity of adverse effects can be increased when Vincristine is combined with Mechlorethamine.
Dactinomycin Dactinomycin The risk or severity of adverse effects can be increased when Dactinomycin is combined with Vincristine.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Vincristine.
Molindone Molindone Vincristine may increase the neurotoxic activities of Molindone.
Methyldopa Methyldopa The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Methyldopa.
Clonidine Clonidine The metabolism of Clonidine can be decreased when combined with Vincristine.
Hydralazine Hydralazine The metabolism of Vincristine can be decreased when combined with Hydralazine.
Cimetidine Cimetidine The metabolism of Vincristine can be decreased when combined with Cimetidine.
Warfarin Warfarin The metabolism of Vincristine can be increased when combined with Warfarin.
Loperamide Loperamide The metabolism of Vincristine can be decreased when combined with Loperamide.
Promethazine Promethazine Vincristine may increase the neurotoxic activities of Promethazine.
Daunorubicin Daunorubicin The metabolism of Vincristine can be decreased when combined with Daunorubicin.
Nitrofurantoin Nitrofurantoin Vincristine may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Griseofulvin Griseofulvin The metabolism of Vincristine can be increased when combined with Griseofulvin.
Digoxin Digoxin Vincristine may decrease the excretion rate of Digoxin which could result in a higher serum level.
Loxapine Loxapine The excretion of Vincristine can be decreased when combined with Loxapine.
Chloroquine Chloroquine The metabolism of Chloroquine can be decreased when combined with Vincristine.
Quinine Quinine The excretion of Vincristine can be decreased when combined with Quinine.
Calcitriol Calcitriol The metabolism of Vincristine can be increased when combined with Calcitriol.
Sulfinpyrazone Sulfinpyrazone The metabolism of Sulfinpyrazone can be increased when combined with Vincristine.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Vincristine.
Secobarbital Secobarbital The metabolism of Vincristine can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Vincristine.
Amitriptyline Amitriptyline The metabolism of Vincristine can be decreased when combined with Amitriptyline.
Imipramine Imipramine The metabolism of Vincristine can be decreased when combined with Imipramine.
Probenecid Probenecid The metabolism of Vincristine can be increased when combined with Probenecid.
Quinidine Quinidine The excretion of Vincristine can be decreased when combined with Quinidine.
Procainamide Procainamide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Procainamide.
Isoniazid Isoniazid The metabolism of Isoniazid can be decreased when combined with Vincristine.
Rifampin Rifampin The serum concentration of Vincristine can be decreased when it is combined with Rifampicin.
Valproic Acid Valproic Acid The metabolism of Vincristine can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The excretion of Vincristine can be decreased when combined with Tamoxifen.
Mitomycin Mitomycin The risk or severity of bronchospasm, shortness of breath, and dyspnea can be increased when Vincristine is combined with Mitomycin.
Levothyroxine Levothyroxine The serum concentration of Vincristine can be decreased when it is combined with Levothyroxine.
Liothyronine Liothyronine The excretion of Liothyronine can be decreased when combined with Vincristine.
Methimazole Methimazole The metabolism of Methimazole can be decreased when combined with Vincristine.
Propylthiouracil Propylthiouracil The risk or severity of adverse effects can be increased when Vincristine is combined with Propylthiouracil.
Dextromethorphan Dextromethorphan The metabolism of Vincristine can be decreased when combined with Dextromethorphan.
Dinoprostone Dinoprostone The excretion of Dinoprostone can be decreased when combined with Vincristine.
Cyclobenzaprine Cyclobenzaprine Vincristine may increase the neurotoxic activities of Cyclobenzaprine.
Niacin Niacin The metabolism of Niacin can be decreased when combined with Vincristine.
Baclofen Baclofen The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Vincristine.
Chlorpheniramine Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Vincristine.
Danazol Danazol The metabolism of Vincristine can be decreased when combined with Danazol.
Disulfiram Disulfiram The metabolism of Disulfiram can be decreased when combined with Vincristine.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The metabolism of Propranolol can be decreased when combined with Vincristine.
Nortriptyline Nortriptyline The serum concentration of Nortriptyline can be increased when it is combined with Vincristine.
Spironolactone Spironolactone Spironolactone may decrease the excretion rate of Vincristine which could result in a higher serum level.
Amphotericin B Injection Amphotericin B Injection The metabolism of Amphotericin B can be decreased when combined with Vincristine.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Vincristine is combined with Mercaptopurine.
Clomiphene Clomiphene The serum concentration of Vincristine can be increased when it is combined with Clomifene.
Fluorouracil Injection Fluorouracil Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Fluorouracil.
Colchicine Colchicine The metabolism of Vincristine can be increased when combined with Colchicine.
Cefaclor Cefaclor Vincristine may decrease the excretion rate of Cefaclor which could result in a higher serum level.
Cephalexin Cephalexin The metabolism of Vincristine can be decreased when combined with Cephalexin.
Dacarbazine Dacarbazine The risk or severity of adverse effects can be increased when Vincristine is combined with Dacarbazine.
Acetazolamide Acetazolamide The metabolism of Vincristine can be decreased when combined with Acetazolamide.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Vincristine.
Ketoconazole Ketoconazole The excretion of Vincristine can be decreased when combined with Ketoconazole.
Thiotepa Injection Thiotepa Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Thiotepa.
Captopril Captopril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Captopril.
Dipyridamole Dipyridamole Vincristine may decrease the excretion rate of Dipyridamole which could result in a higher serum level.
Vinblastine Vinblastine The metabolism of Vincristine can be increased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Vincristine can be decreased when combined with Metoprolol.
Hydroxyzine Hydroxyzine The metabolism of Hydroxyzine can be decreased when combined with Vincristine.
Thiothixene Thiothixene Vincristine may increase the neurotoxic activities of Thiothixene.
Chlorambucil Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Vincristine.
Alprazolam Alprazolam The metabolism of Vincristine can be decreased when combined with Alprazolam.
Triazolam Triazolam The metabolism of Triazolam can be decreased when combined with Vincristine.
Trimethoprim Trimethoprim The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Trimethoprim is combined with Vincristine.
Diltiazem Diltiazem The metabolism of Vincristine can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Nifedipine can be increased when combined with Vincristine.
Verapamil Verapamil The excretion of Vincristine can be decreased when combined with Verapamil.
Atenolol Atenolol Atenolol may decrease the excretion rate of Vincristine which could result in a higher serum level.
Cisplatin Injection Cisplatin Injection The risk or severity of adverse effects can be increased when Cisplatin is combined with Vincristine.
Bumetanide Bumetanide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Bumetanide.
Streptozocin Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with Vincristine.
Etoposide Etoposide The metabolism of Vincristine can be increased when combined with Etoposide.
Glyburide Glyburide The metabolism of Glyburide can be decreased when combined with Vincristine.
Glipizide Glipizide Vincristine may decrease the excretion rate of Glipizide which could result in a higher serum level.
Dicloxacillin Dicloxacillin The metabolism of Vincristine can be increased when combined with Dicloxacillin.
Nafcillin Injection Nafcillin Injection The metabolism of Vincristine can be increased when combined with Nafcillin.
Pentamidine Injection Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Vincristine.
Leuprolide Injection Leuprolide Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Vincristine.
Gemfibrozil Gemfibrozil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Gemfibrozil.
Pimozide Pimozide The metabolism of Pimozide can be decreased when combined with Vincristine.
Enalapril Enalapril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Enalapril.
Amiodarone Amiodarone The excretion of Vincristine can be decreased when combined with Amiodarone.
Buspirone Buspirone The metabolism of Vincristine can be decreased when combined with Buspirone.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Vincristine.
Ciprofloxacin Ciprofloxacin The metabolism of Vincristine can be decreased when combined with Ciprofloxacin.
Diclofenac Diclofenac Vincristine may decrease the excretion rate of Diclofenac which could result in a higher serum level.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Vincristine.
Clozapine Clozapine The metabolism of Vincristine can be increased when combined with Clozapine.
Idarubicin Idarubicin The risk or severity of adverse effects can be increased when Vincristine is combined with Idarubicin.
Ofloxacin Ofloxacin Vincristine may decrease the excretion rate of Ofloxacin which could result in a higher serum level.
Didanosine Didanosine Vincristine may increase the neurotoxic activities of Didanosine.
Fludarabine Injection Fludarabine Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Fludarabine.
Pentostatin Injection Pentostatin Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Pentostatin.
Clarithromycin Clarithromycin The excretion of Vincristine can be decreased when combined with Clarithromycin.
Felodipine Felodipine The metabolism of Felodipine can be decreased when combined with Vincristine.
Pravastatin Pravastatin Pravastatin may decrease the excretion rate of Vincristine which could result in a higher serum level.
Simvastatin Simvastatin The excretion of Vincristine can be decreased when combined with Simvastatin.
Filgrastim Injection Filgrastim Injection The risk or severity of peripheral neuropathy can be increased when Filgrastim is combined with Vincristine.
Epoetin Alfa, Injection Epoetin Alfa, Injection The risk or severity of peripheral neuropathy can be increased when Erythropoietin is combined with Vincristine.
Teniposide Injection Teniposide Injection Teniposide may increase the neurotoxic activities of Vincristine.
Itraconazole Itraconazole The metabolism of Vincristine can be decreased when combined with Itraconazole.
Sargramostim Sargramostim The risk or severity of peripheral neuropathy can be increased when Sargramostim is combined with Vincristine.
Rifabutin Rifabutin The metabolism of Vincristine can be increased when combined with Rifabutin.
Bisoprolol Bisoprolol The serum concentration of Vincristine can be increased when it is combined with Bisoprolol.
Doxazosin Doxazosin The metabolism of Vincristine can be decreased when combined with Doxazosin.
Isradipine Isradipine The metabolism of Vincristine can be decreased when combined with Isradipine.
Omeprazole Omeprazole The metabolism of Vincristine can be increased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Cisapride can be decreased when combined with Vincristine.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Vincristine.
Venlafaxine Venlafaxine Venlafaxine may increase the excretion rate of Vincristine which could result in a lower serum level and potentially a reduction in efficacy.
Nizatidine Nizatidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Nizatidine.
Stavudine Stavudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Stavudine.
Famciclovir Famciclovir The metabolism of Vincristine can be decreased when combined with Famciclovir.
Fluvoxamine Fluvoxamine The metabolism of Vincristine can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Nefazodone can be decreased when combined with Vincristine.
Losartan Losartan The metabolism of Losartan can be decreased when combined with Vincristine.
Vinorelbine Injection Vinorelbine Injection The risk or severity of adverse effects can be increased when Vinorelbine is combined with Vincristine.
Carboplatin Injection Carboplatin Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Carboplatin.
Lansoprazole Lansoprazole The metabolism of Vincristine can be increased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Vincristine.
Pegaspargase Injection Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Vincristine.
Nicardipine Nicardipine The metabolism of Nicardipine can be decreased when combined with Vincristine.
Ticlopidine Ticlopidine The metabolism of Vincristine can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The excretion of Vincristine can be decreased when combined with Saquinavir.
Nisoldipine Nisoldipine The metabolism of Vincristine can be decreased when combined with Nisoldipine.
Lamivudine Lamivudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Lamivudine.
Glimepiride Glimepiride Glimepiride may decrease the excretion rate of Vincristine which could result in a higher serum level.
Anastrozole Anastrozole The risk or severity of cardiotoxicity can be increased when Vincristine is combined with Anastrozole.
Gemcitabine Injection Gemcitabine Injection The risk or severity of adverse effects can be increased when Gemcitabine is combined with Vincristine.
Indinavir Indinavir The metabolism of Vincristine can be decreased when combined with Indinavir.
Ritonavir Ritonavir The serum concentration of Vincristine can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Vincristine.
Clomipramine Clomipramine Vincristine may increase the neurotoxic activities of Clomipramine.
Zafirlukast Zafirlukast The metabolism of Vincristine can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine The metabolism of Vincristine can be decreased when combined with Mirtazapine.
Topiramate Topiramate The metabolism of Vincristine can be increased when combined with Topiramate.
Valsartan Valsartan The excretion of Valsartan can be decreased when combined with Vincristine.
Nelfinavir Nelfinavir The metabolism of Vincristine can be decreased when combined with Nelfinavir.
Fexofenadine Fexofenadine The serum concentration of Fexofenadine can be increased when it is combined with Vincristine.
Azithromycin Azithromycin The metabolism of Vincristine can be decreased when combined with Azithromycin.
Loratadine Loratadine Loratadine may decrease the excretion rate of Vincristine which could result in a higher serum level.
Carvedilol Carvedilol The excretion of Vincristine can be decreased when combined with Carvedilol.
Flutamide Flutamide The metabolism of Vincristine can be decreased when combined with Flutamide.
Bicalutamide Bicalutamide The metabolism of Vincristine can be decreased when combined with Bicalutamide.
Propafenone Propafenone The excretion of Vincristine can be decreased when combined with Propafenone.
Letrozole Letrozole The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Letrozole.
Raloxifene Raloxifene The metabolism of Raloxifene can be decreased when combined with Vincristine.
Irbesartan Irbesartan The metabolism of Vincristine can be decreased when combined with Irbesartan.
Finasteride Finasteride The metabolism of Finasteride can be decreased when combined with Vincristine.
Quetiapine Quetiapine The metabolism of Quetiapine can be decreased when combined with Vincristine.
Paroxetine Paroxetine The metabolism of Vincristine can be decreased when combined with Paroxetine.
Citalopram Citalopram The metabolism of Vincristine can be decreased when combined with Citalopram.
Capecitabine Capecitabine The risk or severity of adverse effects can be increased when Vincristine is combined with Capecitabine.
Efavirenz Efavirenz The metabolism of Vincristine can be increased when combined with Efavirenz.
Sildenafil Sildenafil The excretion of Vincristine can be decreased when combined with Sildenafil.
Trastuzumab Injection Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Vincristine.
Celecoxib Celecoxib Celecoxib may decrease the excretion rate of Vincristine which could result in a higher serum level.
Rosiglitazone Rosiglitazone Rosiglitazone may decrease the excretion rate of Vincristine which could result in a higher serum level.
Thalidomide Thalidomide The risk or severity of adverse effects can be increased when Vincristine is combined with Thalidomide.
Nateglinide Nateglinide The metabolism of Nateglinide can be decreased when combined with Vincristine.
Rabeprazole Rabeprazole The metabolism of Vincristine can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Terbinafine can be increased when combined with Vincristine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists

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