Zolmitriptan
Generic name: Pronounced as (zohl mi trip' tan)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 01/15/2022
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Drug interactions
Why is this medication prescribed?
Zolmitriptan is used to treat the symptoms of migraine headaches (severe throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound and light). Zolmitriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels around the brain, stopping pain signals from being sent to the brain, and blocking the release of certain natural substances that cause pain, nausea, and other symptoms of migraine. Zolmitriptan does not prevent migraine attacks or reduce the number of headaches you have.
How should this medicine be used?
Zolmitriptan comes as a tablet and an orally disintegrating tablet (tablet that dissolves quickly in the mouth) to take by mouth. It is usually taken at the first sign of a migraine headache. If your symptoms improve after you take zolmitriptan but return after 2 hours or longer, you may take a second tablet. However, if your symptoms do not improve after you take zolmitriptan, do not take a second tablet without calling your doctor. Your doctor will tell you the maximum number of tablets or orally disintegrating tablets you may take in a 24-hour period. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take zolmitriptan exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
You may take your first dose of zolmitriptan in a doctor's office or other medical facility where you can be monitored for serious reactions.
If your doctor has prescribed a dose lower than 2.5 mg, you may use your fingers to break the 2.5-mg tablet on the line that divides it in half. However, you should not break or split the orally disintegrating tablet.
To take the orally disintegrating tablet, use dry hands to peel back the foil packaging. Immediately take out the tablet and place it on your tongue. The tablet will quickly dissolve and can be swallowed with saliva. No water is needed to swallow disintegrating tablets. Do not open the foil packaging or remove the orally disintegrating tablet until just before you are ready to take it.
Call your doctor if your headaches do not get better or occur more frequently after taking zolmitriptan.
If you take zolmitriptan more often or for longer than the recommended period of time, your headaches may get worse or may occur more frequently. You should not take zolmitriptan or any other headache medication for more than 10 days per month. Call your doctor if you need to take zolmitriptan to treat more than three headaches in a 1-month period.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking zolmitriptan,
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tell your doctor and pharmacist if you are allergic to zolmitriptan, any other medications, or any of the ingredients in zolmitriptan tablets or orally disintegrating tablets. Ask your pharmacist for a list of the ingredients.
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do not take zolmitriptan if you have taken any of the following medications in the past 24 hours: other selective serotonin receptor agonists such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), or sumatriptan (Imitrex, in Treximet); or ergot-type medications such as bromocriptine (Parlodel), cabergoline , dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Hydergine), ergonovine (Ergotrate), ergotamine (Cafergot, Ergomar, Wigraine), methylergonovine (Methergine), methysergide (Sansert), and pergolide (Permax).
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do not take zolmitriptan if you are taking a monoamine oxidase A (MAO-A) inhibitor such as isocarboxazid (Marplan), phenelzine (Parnate), or tranylcypromine (Nardil) or if you have taken one of these medications in the past 2 weeks.
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tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, or herbal products you are taking or plan to take. Be sure to mention any of the following: acetaminophen (Tylenol); antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); cimetidine (Tagamet); oral contraceptives ('birth control pills'); propranolol (Inderal); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft); and selective serotonin/norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Pristiq), duloxetine (Cymbalta), sibutramine (Meridia), and venlafaxine (Effexor). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
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tell your doctor if you have or have ever had heart disease; a heart attack; angina (chest pain); irregular heartbeats; stroke or 'mini-stroke'; or circulation problems such as varicose veins, blood clots in the legs, Raynaud's disease (problems with blood flow to the fingers, toes, ears, and nose), or ischemic bowel disease (bloody diarrhea and stomach pain caused by decreased blood flow to the intestines). Your doctor may tell you not to take zolmitriptan.
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tell your doctor if you smoke or are overweight; if you have or have ever had high blood pressure, high cholesterol, diabetes, or liver or kidney disease; if you have gone through menopause (change of life); or if any family members have or have ever had heart disease or stroke.
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tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you plan to be sexually active while you are taking this medication, talk to your doctor about effective methods of birth control. If you become pregnant while taking zolmitriptan, call your doctor.
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you should know that this medication may make you drowsy or dizzy. Do not drive a car or operate machinery until you know how zolmitriptan affects you.
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talk to your doctor about your headache symptoms to make sure they are caused by migraine. Zolmitriptan should not be used to treat certain types of migraine headaches (hemiplegic or basilar) or other types of headaches (such as cluster headaches).
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if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent damage to your brain that can cause severe intellectual disability), you should know that the orally disintegrating tablets contain aspartame that forms phenylalanine.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What side effects can this medication cause?
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Zolmitriptan may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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feeling warm or cold
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drowsiness
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dry mouth
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nausea
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heartburn
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sweating
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dizziness or faintness
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Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:
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pain, tightness, pressure, or heaviness in the chest, throat, neck, or jaw
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slow or difficult speech
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weakness or numbness of an arm or leg
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fast, pounding, or irregular heartbeat
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bloody diarrhea
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sudden or severe stomach pain
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paleness or blue color of the fingers and toes
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shortness of breath
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swelling of the eyes, face, lips, tongue, or throat
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difficulty breathing or swallowing
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hoarseness
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rash
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hives
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pain, burning, or tingling in the hands or feet
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat, and moisture (not in the bathroom). Dispose of any orally disintegrating tablets that you removed from the blister pack but did not use immediately.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include:
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extreme drowsiness
What OTHER INFORMATION should I know?
Keep all appointments with your doctor. Your blood pressure should be checked regularly.
You should keep a headache diary by writing down when you have headaches and when you take zolmitriptan.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Moxifloxacin | Moxifloxacin The metabolism of Zolmitriptan can be decreased when combined with Moxifloxacin. |
Insulin Glargine (rDNA origin) Injection | Insulin Glargine (rDNA origin) Injection The metabolism of Zolmitriptan can be increased when combined with Insulin glargine. |
Leflunomide | Leflunomide The serum concentration of Zolmitriptan can be decreased when it is combined with Leflunomide. |
Nevirapine | Nevirapine The metabolism of Zolmitriptan can be decreased when combined with Nevirapine. |
Dolasetron | Dolasetron The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Dolasetron. |
Aminophylline | Aminophylline The metabolism of Aminophylline can be decreased when combined with Zolmitriptan. |
Anagrelide | Anagrelide The metabolism of Zolmitriptan can be decreased when combined with Anagrelide. |
Candesartan | Candesartan Zolmitriptan may decrease the antihypertensive activities of Candesartan. |
Cilostazol | Cilostazol The metabolism of Cilostazol can be decreased when combined with Zolmitriptan. |
Clopidogrel | Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Zolmitriptan. |
Diphenoxylate | Diphenoxylate The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Diphenoxylate. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) The metabolism of Zolmitriptan can be decreased when combined with Conjugated estrogens. |
Guanfacine | Guanfacine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Guanfacine. |
Methylergonovine | Methylergonovine Methylergometrine may increase the vasoconstricting activities of Zolmitriptan. |
Naratriptan | Naratriptan The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Naratriptan. |
Olsalazine | Olsalazine The risk or severity of hypertension can be increased when Zolmitriptan is combined with Olsalazine. |
Paregoric | Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Zolmitriptan. |
Penbutolol | Penbutolol Zolmitriptan may decrease the antihypertensive activities of Acebutolol. |
Pentazocine | Pentazocine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Pentazocine. |
Ranitidine | Ranitidine The metabolism of Zolmitriptan can be decreased when combined with Ranitidine. |
Reserpine | Reserpine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Reserpine. |
Rizatriptan | Rizatriptan The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Rizatriptan. |
Sumatriptan | Sumatriptan The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Sumatriptan. |
Tizanidine | Tizanidine The metabolism of Tizanidine can be decreased when combined with Zolmitriptan. |
Famotidine Injection | Famotidine Injection The metabolism of Zolmitriptan can be decreased when combined with Famotidine. |
Hydromorphone Injection | Hydromorphone Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Hydromorphone. |
Interferon Beta-1b Injection | Interferon Beta-1b Injection The metabolism of Zolmitriptan can be decreased when combined with Interferon beta-1b. |
Interferon Gamma-1b Injection | Interferon Gamma-1b Injection The metabolism of Zolmitriptan can be decreased when combined with Interferon gamma-1b. |
Levofloxacin Injection | Levofloxacin Injection The metabolism of Zolmitriptan can be decreased when combined with Levofloxacin. |
Meperidine Injection | Meperidine Injection The metabolism of Zolmitriptan can be increased when combined with Meperidine. |
Metoclopramide Injection | Metoclopramide Injection The risk or severity of sedation can be increased when Zolmitriptan is combined with Metoclopramide. |
Morphine Injection | Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Zolmitriptan. |
Altretamine | Altretamine The metabolism of Zolmitriptan can be decreased when combined with Amphetamine. |
Cyclosporine | Cyclosporine The risk or severity of hypertension can be increased when Cyclosporine is combined with Zolmitriptan. |
Ondansetron | Ondansetron The metabolism of Zolmitriptan can be decreased when combined with Ondansetron. |
Granisetron | Granisetron The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Granisetron. |
Torsemide | Torsemide Zolmitriptan may decrease the antihypertensive activities of Torasemide. |
Olanzapine | Olanzapine The metabolism of Olanzapine can be decreased when combined with Zolmitriptan. |
Alosetron | Alosetron The metabolism of Zolmitriptan can be decreased when combined with Alosetron. |
Entacapone | Entacapone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Entacapone. |
Eprosartan | Eprosartan Zolmitriptan may decrease the antihypertensive activities of Eprosartan. |
Meloxicam | Meloxicam The risk or severity of hypertension can be increased when Zolmitriptan is combined with Meloxicam. |
Oxcarbazepine | Oxcarbazepine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Oxcarbazepine. |
Telmisartan | Telmisartan Zolmitriptan may decrease the antihypertensive activities of Telmisartan. |
Zaleplon | Zaleplon The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Zaleplon. |
Anakinra | Anakinra The metabolism of Zolmitriptan can be increased when combined with Anakinra. |
Desloratadine | Desloratadine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Desloratadine. |
Linezolid | Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Zolmitriptan. |
Trimipramine | Trimipramine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Trimipramine. |
Etanercept Injection | Etanercept Injection The metabolism of Zolmitriptan can be increased when combined with Etanercept. |
Glycopyrrolate | Glycopyrrolate Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium. |
Modafinil | Modafinil The metabolism of Zolmitriptan can be increased when combined with Modafinil. |
Perindopril | Perindopril Zolmitriptan may decrease the antihypertensive activities of Perindopril. |
Choline Magnesium Trisalicylate | Choline Magnesium Trisalicylate The risk or severity of hypertension can be increased when Zolmitriptan is combined with Choline magnesium trisalicylate. |
Dutasteride | Dutasteride The risk or severity of hypertension can be increased when Zolmitriptan is combined with Dutasteride. |
Epinephrine Injection | Epinephrine Injection The risk or severity of hypertension can be increased when Zolmitriptan is combined with Epinephrine. |
Eplerenone | Eplerenone Zolmitriptan may decrease the antihypertensive activities of Eplerenone. |
Escitalopram | Escitalopram The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Escitalopram. |
Olmesartan | Olmesartan Zolmitriptan may decrease the antihypertensive activities of Olmesartan. |
Zonisamide | Zonisamide The metabolism of Zolmitriptan can be decreased when combined with Zonisamide. |
Adalimumab Injection | Adalimumab Injection The metabolism of Zolmitriptan can be increased when combined with Adalimumab. |
Aripiprazole | Aripiprazole The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Aripiprazole. |
Atomoxetine | Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Zolmitriptan. |
Dexmethylphenidate | Dexmethylphenidate The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Dexmethylphenidate. |
Almotriptan | Almotriptan The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Almotriptan. |
Eletriptan | Eletriptan The risk or severity of vasospastic reactions can be increased when Eletriptan is combined with Zolmitriptan. |
Interferon Beta-1a Subcutaneous Injection | Interferon Beta-1a Subcutaneous Injection The metabolism of Zolmitriptan can be decreased when combined with Interferon beta-1a. |
Tegaserod | Tegaserod The metabolism of Zolmitriptan can be decreased when combined with Tegaserod. |
Tadalafil | Tadalafil Zolmitriptan may decrease the antihypertensive activities of Tadalafil. |
Frovatriptan | Frovatriptan The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Frovatriptan. |
Gemifloxacin | Gemifloxacin The metabolism of Zolmitriptan can be decreased when combined with Gemifloxacin. |
Apomorphine Injection | Apomorphine Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Apomorphine. |
Infliximab Injection | Infliximab Injection The metabolism of Zolmitriptan can be increased when combined with Infliximab. |
Protriptyline | Protriptyline The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Protriptyline. |
Duloxetine | Duloxetine The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Duloxetine. |
Trospium | Trospium Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Trospium. |
Bosentan | Bosentan Zolmitriptan may decrease the antihypertensive activities of Bosentan. |
Cinacalcet | Cinacalcet The metabolism of Cinacalcet can be decreased when combined with Zolmitriptan. |
Erlotinib | Erlotinib The metabolism of Erlotinib can be decreased when combined with Zolmitriptan. |
Eszopiclone | Eszopiclone The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Eszopiclone. |
Solifenacin | Solifenacin Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin. |
Dextroamphetamine | Dextroamphetamine The metabolism of Zolmitriptan can be decreased when combined with Amphetamine. |
Entecavir | Entecavir The metabolism of Entecavir can be decreased when combined with Zolmitriptan. |
Peginterferon Alfa-2a Injection | Peginterferon Alfa-2a Injection The metabolism of Zolmitriptan can be decreased when combined with Peginterferon alfa-2a. |
Peginterferon Alfa-2b (PEG-Intron) | Peginterferon Alfa-2b (PEG-Intron) The metabolism of Zolmitriptan can be decreased when combined with Peginterferon alfa-2b. |
Sodium Oxybate | Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan. |
Isocarboxazid | Isocarboxazid The metabolism of Zolmitriptan can be decreased when combined with Isocarboxazid. |
Ramelteon | Ramelteon The metabolism of Ramelteon can be decreased when combined with Zolmitriptan. |
Darifenacin | Darifenacin Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Darifenacin. |
Fentanyl | Fentanyl The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Fentanyl. |
Pregabalin | Pregabalin The therapeutic efficacy of Zolmitriptan can be increased when used in combination with Pregabalin. |
Deferasirox | Deferasirox The metabolism of Zolmitriptan can be decreased when combined with Deferasirox. |
Phenylephrine | Phenylephrine The metabolism of Zolmitriptan can be increased when combined with Phenylephrine. |
Felbamate | Felbamate The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Felbamate. |
Abatacept Injection | Abatacept Injection The metabolism of Zolmitriptan can be increased when combined with Abatacept. |
Rasagiline | Rasagiline The metabolism of Zolmitriptan can be decreased when combined with Rasagiline. |
Imatinib | Imatinib The metabolism of Imatinib can be decreased when combined with Zolmitriptan. |
Albuterol | Albuterol The risk or severity of hypertension can be increased when Zolmitriptan is combined with Salbutamol. |
Paliperidone | Paliperidone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Paliperidone. |
Bortezomib | Bortezomib The metabolism of Zolmitriptan can be decreased when combined with Bortezomib. |
Insulin Glulisine (rDNA origin) Injection | Insulin Glulisine (rDNA origin) Injection The metabolism of Zolmitriptan can be increased when combined with Insulin glulisine. |
Primaquine | Primaquine The metabolism of Zolmitriptan can be increased when combined with Primaquine. |
Aliskiren | Aliskiren Zolmitriptan may decrease the antihypertensive activities of Aliskiren. |
Pemetrexed Injection | Pemetrexed Injection The metabolism of Pemetrexed can be decreased when combined with Zolmitriptan. |
Dimenhydrinate | Dimenhydrinate The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Dimenhydrinate. |
Lisdexamfetamine | Lisdexamfetamine The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Lisdexamfetamine. |
Nabilone | Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan. |
Sorafenib | Sorafenib The metabolism of Sorafenib can be decreased when combined with Zolmitriptan. |
Dronabinol | Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan. |
Levocetirizine | Levocetirizine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Levocetirizine. |
Dasatinib | Dasatinib The metabolism of Dasatinib can be decreased when combined with Zolmitriptan. |
Mexiletine | Mexiletine The metabolism of Zolmitriptan can be decreased when combined with Mexiletine. |
Armodafinil | Armodafinil The metabolism of Zolmitriptan can be increased when combined with Armodafinil. |
Desmopressin | Desmopressin The risk or severity of hypertension can be increased when Desmopressin is combined with Zolmitriptan. |
OnabotulinumtoxinA Injection | OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Zolmitriptan. |
RimabotulinumtoxinB Injection | RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Zolmitriptan. |
Desvenlafaxine | Desvenlafaxine The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Desvenlafaxine. |
Nebivolol | Nebivolol Zolmitriptan may decrease the antihypertensive activities of Nebivolol. |
Bendamustine Injection | Bendamustine Injection The metabolism of Bendamustine can be decreased when combined with Zolmitriptan. |
Flecainide | Flecainide The metabolism of Flecainide can be decreased when combined with Zolmitriptan. |
Certolizumab Injection | Certolizumab Injection The metabolism of Zolmitriptan can be increased when combined with Certolizumab pegol. |
Praziquantel | Praziquantel The metabolism of Praziquantel can be decreased when combined with Zolmitriptan. |
Rufinamide | Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Zolmitriptan. |
Midazolam | Midazolam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Midazolam. |
Naltrexone Injection | Naltrexone Injection The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Naltrexone. |
Eltrombopag | Eltrombopag The metabolism of Eltrombopag can be decreased when combined with Zolmitriptan. |
Milnacipran | Milnacipran The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Milnacipran. |
Fesoterodine | Fesoterodine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine. |
Betaxolol | Betaxolol The metabolism of Zolmitriptan can be decreased when combined with Betaxolol. |
Iloperidone | Iloperidone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Iloperidone. |
Lacosamide | Lacosamide The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Lacosamide. |
Dronedarone | Dronedarone The risk or severity of hypertension can be increased when Zolmitriptan is combined with Dronedarone. |
AbobotulinumtoxinA Injection | AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Zolmitriptan. |
Palonosetron Injection | Palonosetron Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Palonosetron. |
Tapentadol | Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan. |
Golimumab Injection | Golimumab Injection The metabolism of Zolmitriptan can be increased when combined with Golimumab. |
Pazopanib | Pazopanib The metabolism of Pazopanib can be decreased when combined with Zolmitriptan. |
Asenapine | Asenapine The metabolism of Asenapine can be decreased when combined with Zolmitriptan. |
Vigabatrin | Vigabatrin The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Vigabatrin. |
Albendazole | Albendazole The metabolism of Albendazole can be decreased when combined with Zolmitriptan. |
Oxymorphone | Oxymorphone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Oxymorphone. |
Tocilizumab Injection | Tocilizumab Injection The metabolism of Zolmitriptan can be increased when combined with Tocilizumab. |
IncobotulinumtoxinA Injection | IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Zolmitriptan. |
Lurasidone | Lurasidone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Lurasidone. |
Acetaminophen Injection | Acetaminophen Injection The metabolism of Acetaminophen can be decreased when combined with Zolmitriptan. |
Vilazodone | Vilazodone The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Vilazodone. |
Terbutaline Injection | Terbutaline Injection The risk or severity of hypertension can be increased when Zolmitriptan is combined with Terbutaline. |
Telaprevir | Telaprevir The metabolism of Zolmitriptan can be decreased when combined with Glecaprevir. |
Abiraterone | Abiraterone The metabolism of Zolmitriptan can be decreased when combined with Abiraterone. |
Clobazam | Clobazam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Clobazam. |
Vemurafenib | Vemurafenib The serum concentration of Zolmitriptan can be increased when it is combined with Vemurafenib. |
Axitinib | Axitinib The metabolism of Axitinib can be decreased when combined with Zolmitriptan. |
Cabergoline | Cabergoline The risk or severity of vasospastic reactions can be increased when Cabergoline is combined with Zolmitriptan. |
Ambrisentan | Ambrisentan Zolmitriptan may decrease the antihypertensive activities of Ambrisentan. |
Ezogabine | Ezogabine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Tiagabine. |
Mirabegron | Mirabegron The risk or severity of hypertension can be increased when Zolmitriptan is combined with Mirabegron. |
Teriflunomide | Teriflunomide The serum concentration of Zolmitriptan can be decreased when it is combined with Teriflunomide. |
Pomalidomide | Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Zolmitriptan. |
Levomilnacipran | Levomilnacipran The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Levomilnacipran. |
Vortioxetine | Vortioxetine The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Vortioxetine. |
Perampanel | Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan. |
Ketorolac Injection | Ketorolac Injection The risk or severity of hypertension can be increased when Zolmitriptan is combined with Ketorolac. |
Simeprevir | Simeprevir The metabolism of Zolmitriptan can be decreased when combined with Simeprevir. |
Dapagliflozin | Dapagliflozin The metabolism of Zolmitriptan can be decreased when combined with Dapagliflozin. |
Apremilast | Apremilast The metabolism of Zolmitriptan can be increased when combined with Apremilast. |
Droxidopa | Droxidopa Zolmitriptan may increase the hypertensive activities of Droxidopa. |
Siltuximab Injection | Siltuximab Injection The metabolism of Zolmitriptan can be increased when combined with Siltuximab. |
Eslicarbazepine | Eslicarbazepine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Eslicarbazepine. |
Belinostat Injection | Belinostat Injection The metabolism of Zolmitriptan can be increased when combined with Belinostat. |
Hydrocodone | Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan. |
Suvorexant | Suvorexant Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
Peginterferon Beta-1a Injection | Peginterferon Beta-1a Injection The metabolism of Zolmitriptan can be decreased when combined with Peginterferon beta-1a. |
Methamphetamine | Methamphetamine The metabolism of Zolmitriptan can be decreased when combined with Metamfetamine. |
Tasimelteon | Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Zolmitriptan. |
Riociguat | Riociguat Zolmitriptan may decrease the antihypertensive activities of Riociguat. |
Pirfenidone | Pirfenidone The metabolism of Zolmitriptan can be decreased when combined with Pirfenidone. |
Secukinumab Injection | Secukinumab Injection The metabolism of Zolmitriptan can be increased when combined with Secukinumab. |
Risperidone Injection | Risperidone Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Risperidone. |
Insulin Human Inhalation | Insulin Human Inhalation The metabolism of Zolmitriptan can be increased when combined with Insulin human. |
Lenvatinib | Lenvatinib The metabolism of Zolmitriptan can be decreased when combined with Lenvatinib. |
Haloperidol Injection | Haloperidol Injection The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Haloperidol. |
Macitentan | Macitentan Zolmitriptan may decrease the antihypertensive activities of Macitentan. |
Flibanserin | Flibanserin The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Flibanserin. |
Brexpiprazole | Brexpiprazole The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Brexpiprazole. |
Ziprasidone Injection | Ziprasidone Injection The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Ziprasidone. |
Cariprazine | Cariprazine The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Cariprazine. |
Eluxadoline | Eluxadoline The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Eluxadoline. |
Insulin Degludec (rDNA Origin) Injection | Insulin Degludec (rDNA Origin) Injection The metabolism of Zolmitriptan can be increased when combined with Insulin degludec. |
Osimertinib | Osimertinib The serum concentration of Zolmitriptan can be decreased when it is combined with Osimertinib. |
Brivaracetam Injection | Brivaracetam Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Brivaracetam. |
Midodrine | Midodrine The risk or severity of hypertension can be increased when Midodrine is combined with Zolmitriptan. |
Selexipag | Selexipag Zolmitriptan may decrease the antihypertensive activities of Selexipag. |
Pimavanserin | Pimavanserin The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Pimavanserin. |
Obeticholic Acid | Obeticholic Acid The metabolism of Zolmitriptan can be decreased when combined with Obeticholic acid. |
Diphenhydramine Injection | Diphenhydramine Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Diphenhydramine. |
Furosemide Injection | Furosemide Injection Zolmitriptan may decrease the antihypertensive activities of Furosemide. |
Rucaparib | Rucaparib The metabolism of Zolmitriptan can be decreased when combined with Rucaparib. |
Doxepin (Insomnia) | Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Zolmitriptan. |
Safinamide | Safinamide The metabolism of Zolmitriptan can be decreased when combined with Safinamide. |
Midostaurin | Midostaurin The metabolism of Zolmitriptan can be decreased when combined with Midostaurin. |
Enasidenib | Enasidenib The metabolism of Zolmitriptan can be decreased when combined with Enasidenib. |
Buprenorphine Injection | Buprenorphine Injection Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
Lofexidine | Lofexidine The therapeutic efficacy of Zolmitriptan can be increased when used in combination with Lofexidine. |
Binimetinib | Binimetinib The metabolism of Binimetinib can be decreased when combined with Zolmitriptan. |
Cannabidiol | Cannabidiol The risk or severity of vasospastic reactions can be increased when Cannabidiol is combined with Zolmitriptan. |
Stiripentol | Stiripentol The metabolism of Zolmitriptan can be decreased when combined with Stiripentol. |
Gilteritinib | Gilteritinib The therapeutic efficacy of Zolmitriptan can be decreased when used in combination with Gilteritinib. |
Rifamycin | Rifamycin The metabolism of Zolmitriptan can be decreased when combined with Rifamycin. |
Emapalumab-lzsg Injection | Emapalumab-lzsg Injection The metabolism of Zolmitriptan can be increased when combined with Emapalumab. |
Siponimod | Siponimod The risk or severity of hypertension can be increased when Zolmitriptan is combined with Siponimod. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic The metabolism of Acyclovir can be decreased when combined with Zolmitriptan. |
Brexanolone Injection | Brexanolone Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Brexanolone. |
Solriamfetol | Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Zolmitriptan. |
Triclabendazole | Triclabendazole The metabolism of Zolmitriptan can be decreased when combined with Triclabendazole. |
Istradefylline | Istradefylline The metabolism of Istradefylline can be decreased when combined with Zolmitriptan. |
Pitolisant | Pitolisant The metabolism of Zolmitriptan can be increased when combined with Pitolisant. |
Phenytoin Injection | Phenytoin Injection The risk or severity of adverse effects can be increased when Phenytoin is combined with Zolmitriptan. |
Fosphenytoin Injection | Fosphenytoin Injection The metabolism of Zolmitriptan can be increased when combined with Fosphenytoin. |
Lumateperone | Lumateperone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Lumateperone. |
Lasmiditan | Lasmiditan The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Lasmiditan. |
Selumetinib | Selumetinib The metabolism of Selumetinib can be decreased when combined with Zolmitriptan. |
Selpercatinib | Selpercatinib The risk or severity of hypertension can be increased when Zolmitriptan is combined with Selpercatinib. |
Capmatinib | Capmatinib The metabolism of Zolmitriptan can be decreased when combined with Capmatinib. |
Lemborexant | Lemborexant The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Lemborexant. |
Fenfluramine | Fenfluramine The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Fenfluramine. |
Satralizumab-mwge Injection | Satralizumab-mwge Injection The serum concentration of Zolmitriptan can be decreased when it is combined with Satralizumab. |
Naxitamab-gqgk Injection | Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Zolmitriptan is combined with Naxitamab. |
Viloxazine | Viloxazine The metabolism of Zolmitriptan can be decreased when combined with Viloxazine. |
Theophylline | Theophylline The metabolism of Zolmitriptan can be decreased when combined with Theophylline. |
Fenoprofen | Fenoprofen The risk or severity of hypertension can be increased when Zolmitriptan is combined with Fenoprofen. |
Indomethacin | Indomethacin The risk or severity of hypertension can be increased when Zolmitriptan is combined with Indomethacin. |
Mefenamic Acid | Mefenamic Acid The risk or severity of hypertension can be increased when Zolmitriptan is combined with Mefenamic acid. |
Naproxen | Naproxen The metabolism of Naproxen can be decreased when combined with Zolmitriptan. |
Tolmetin | Tolmetin The risk or severity of hypertension can be increased when Zolmitriptan is combined with Tolmetin. |
Sulindac | Sulindac The risk or severity of hypertension can be increased when Zolmitriptan is combined with Sulindac. |
Trazodone | Trazodone The risk or severity of serotonin syndrome can be increased when Trazodone is combined with Zolmitriptan. |
Phenobarbital | Phenobarbital The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Phenobarbital. |
Metaxalone | Metaxalone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Metaxalone. |
Levorphanol | Levorphanol The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Levorphanol. |
Primidone | Primidone The metabolism of Zolmitriptan can be increased when combined with Primidone. |
Methsuximide | Methsuximide The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Methsuximide. |
Diethylpropion | Diethylpropion The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Diethylpropion. |
Chlorpromazine | Chlorpromazine The metabolism of Chlorpromazine can be decreased when combined with Zolmitriptan. |
Diazepam | Diazepam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Diazepam. |
Oxazepam | Oxazepam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Oxazepam. |
Flurazepam | Flurazepam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Flurazepam. |
Clorazepate | Clorazepate The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Clorazepic acid. |
Lorazepam | Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Zolmitriptan. |
Phenoxybenzamine | Phenoxybenzamine The risk or severity of hypertension can be increased when Zolmitriptan is combined with Phenoxybenzamine. |
Carmustine | Carmustine The metabolism of Zolmitriptan can be decreased when combined with Carmustine. |
Amantadine | Amantadine The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Amantadine. |
Codeine | Codeine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Codeine. |
Meprobamate | Meprobamate The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Meprobamate. |
Chlordiazepoxide | Chlordiazepoxide The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Chlordiazepoxide. |
Bromocriptine | Bromocriptine Bromocriptine may increase the vasoconstricting activities of Zolmitriptan. |
Metaproterenol | Metaproterenol The risk or severity of hypertension can be increased when Zolmitriptan is combined with Orciprenaline. |
Tranylcypromine | Tranylcypromine The metabolism of Zolmitriptan can be decreased when combined with Tranylcypromine. |
Phenelzine | Phenelzine The metabolism of Zolmitriptan can be decreased when combined with Phenelzine. |
Procarbazine | Procarbazine The metabolism of Zolmitriptan can be decreased when combined with Procarbazine. |
Ergoloid Mesylates | Ergoloid Mesylates Ergoloid mesylate may increase the vasoconstricting activities of Zolmitriptan. |
Minocycline | Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan. |
Prochlorperazine | Prochlorperazine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Prochlorperazine. |
Thioridazine | Thioridazine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Thioridazine. |
Trifluoperazine | Trifluoperazine The metabolism of Trifluoperazine can be decreased when combined with Zolmitriptan. |
Oxycodone | Oxycodone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Oxycodone. |
Methadone | Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Zolmitriptan. |
Oxybutynin | Oxybutynin Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin. |
Benztropine | Benztropine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Benzatropine. |
Maprotiline | Maprotiline The metabolism of Maprotiline can be decreased when combined with Zolmitriptan. |
Ibuprofen | Ibuprofen The risk or severity of hypertension can be increased when Zolmitriptan is combined with Ibuprofen. |
Trihexyphenidyl | Trihexyphenidyl Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl. |
Orphenadrine | Orphenadrine The metabolism of Zolmitriptan can be decreased when combined with Orphenadrine. |
Perphenazine | Perphenazine The metabolism of Perphenazine can be decreased when combined with Zolmitriptan. |
Azathioprine | Azathioprine The metabolism of Azathioprine can be decreased when combined with Zolmitriptan. |
Fluphenazine | Fluphenazine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Fluphenazine. |
Phentermine | Phentermine The metabolism of Zolmitriptan can be decreased when combined with Phentermine. |
Methylphenidate | Methylphenidate The risk or severity of hypertension can be increased when Zolmitriptan is combined with Methylphenidate. |
Amoxapine | Amoxapine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Amoxapine. |
Sulfasalazine | Sulfasalazine The risk or severity of hypertension can be increased when Zolmitriptan is combined with Sulfasalazine. |
Carbamazepine | Carbamazepine The metabolism of Zolmitriptan can be decreased when combined with Carbamazepine. |
Molindone | Molindone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Molindone. |
Methyldopa | Methyldopa Zolmitriptan may decrease the antihypertensive activities of Methyldopa. |
Clonidine | Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Zolmitriptan. |
Prazosin | Prazosin Zolmitriptan may decrease the antihypertensive activities of Prazosin. |
Hydralazine | Hydralazine Zolmitriptan may decrease the antihypertensive activities of Hydralazine. |
Cimetidine | Cimetidine The serum concentration of Zolmitriptan can be increased when it is combined with Cimetidine. |
Warfarin | Warfarin The metabolism of Warfarin can be decreased when combined with Zolmitriptan. |
Clonazepam | Clonazepam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Clonazepam. |
Promethazine | Promethazine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Promethazine. |
Meclofenamate | Meclofenamate The risk or severity of hypertension can be increased when Zolmitriptan is combined with Meclofenamic acid. |
Griseofulvin | Griseofulvin The metabolism of Zolmitriptan can be increased when combined with Griseofulvin. |
Loxapine | Loxapine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Loxapine. |
Quinine | Quinine The metabolism of Quinine can be decreased when combined with Zolmitriptan. |
Ethosuximide | Ethosuximide The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Ethosuximide. |
Triamterene | Triamterene The metabolism of Triamterene can be decreased when combined with Zolmitriptan. |
Chlorothiazide | Chlorothiazide Zolmitriptan may decrease the antihypertensive activities of Chlorothiazide. |
Chlorthalidone | Chlorthalidone Zolmitriptan may decrease the antihypertensive activities of Chlorthalidone. |
Metolazone | Metolazone Zolmitriptan may decrease the antihypertensive activities of Metolazone. |
Secobarbital | Secobarbital The metabolism of Zolmitriptan can be increased when combined with Secobarbital. |
Desipramine | Desipramine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Desipramine. |
Amitriptyline | Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Zolmitriptan. |
Imipramine | Imipramine The metabolism of Zolmitriptan can be decreased when combined with Imipramine. |
Quinidine | Quinidine The metabolism of Zolmitriptan can be decreased when combined with Quinidine. |
Isoniazid | Isoniazid The metabolism of Zolmitriptan can be decreased when combined with Isoniazid. |
Rifampin | Rifampin The metabolism of Zolmitriptan can be increased when combined with Rifampicin. |
Disopyramide | Disopyramide The metabolism of Zolmitriptan can be decreased when combined with Disopyramide. |
Valproic Acid | Valproic Acid The metabolism of Zolmitriptan can be decreased when combined with Valproic acid. |
Tamoxifen | Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Zolmitriptan. |
Butabarbital | Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Zolmitriptan. |
Methimazole | Methimazole The metabolism of Zolmitriptan can be decreased when combined with Methimazole. |
Dextromethorphan | Dextromethorphan The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Dextromethorphan. |
Cyclobenzaprine | Cyclobenzaprine The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Cyclobenzaprine. |
Baclofen | Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Zolmitriptan. |
Doxylamine | Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan. |
Cyproheptadine | Cyproheptadine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Cyproheptadine. |
Clemastine | Clemastine The risk or severity of adverse effects can be increased when Clemastine is combined with Zolmitriptan. |
Chlorpheniramine | Chlorpheniramine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Chlorpheniramine. |
Brompheniramine | Brompheniramine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Dexbrompheniramine. |
Meclizine | Meclizine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Meclizine. |
Hydrochlorothiazide | Hydrochlorothiazide Zolmitriptan may decrease the antihypertensive activities of Hydrochlorothiazide. |
Dantrolene | Dantrolene The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Dantrolene. |
Chlorzoxazone | Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Zolmitriptan. |
Carisoprodol | Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Zolmitriptan. |
Methocarbamol | Methocarbamol The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Methocarbamol. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The serum concentration of the active metabolites of Zolmitriptan can be reduced when Zolmitriptan is used in combination with Propranolol resulting in a loss in efficacy. |
Minoxidil | Minoxidil Zolmitriptan may decrease the antihypertensive activities of Minoxidil. |
Pseudoephedrine | Pseudoephedrine The metabolism of Zolmitriptan can be decreased when combined with Pseudoephedrine. |
Nortriptyline | Nortriptyline Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Nortriptyline. |
Nadolol | Nadolol Zolmitriptan may decrease the antihypertensive activities of Nadolol. |
Butorphanol Injection | Butorphanol Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Butorphanol. |
Nalbuphine Injection | Nalbuphine Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Nalbuphine. |
Trimethobenzamide | Trimethobenzamide The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Trimethobenzamide. |
Flavoxate | Flavoxate Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Flavoxate. |
Fluorouracil Injection | Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Zolmitriptan. |
Dacarbazine | Dacarbazine The metabolism of Dacarbazine can be decreased when combined with Zolmitriptan. |
Acetazolamide | Acetazolamide The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Acetazolamide. |
Ketoconazole | Ketoconazole The metabolism of Zolmitriptan can be decreased when combined with Ketoconazole. |
Pyrantel | Pyrantel The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Pyrantel. |
Captopril | Captopril Zolmitriptan may decrease the antihypertensive activities of Captopril. |
Isoxsuprine | Isoxsuprine The risk or severity of hypertension can be increased when Zolmitriptan is combined with Isoxsuprine. |
Metoprolol | Metoprolol Zolmitriptan may decrease the antihypertensive activities of Metoprolol. |
Hydroxyzine | Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan. |
Thiothixene | Thiothixene The metabolism of Thiothixene can be decreased when combined with Zolmitriptan. |
Aspirin | Aspirin The risk or severity of hypertension can be increased when Zolmitriptan is combined with Acetylsalicylic acid. |
Salsalate | Salsalate The risk or severity of hypertension can be increased when Zolmitriptan is combined with Salsalate. |
Alprazolam | Alprazolam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Alprazolam. |
Temazepam | Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Zolmitriptan. |
Triazolam | Triazolam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Triazolam. |
Dicyclomine | Dicyclomine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine. |
Hyoscyamine | Hyoscyamine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine. |
Propantheline | Propantheline Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Propantheline. |
Diltiazem | Diltiazem Zolmitriptan may decrease the antihypertensive activities of Diltiazem. |
Nifedipine | Nifedipine The metabolism of Nifedipine can be decreased when combined with Zolmitriptan. |
Timolol | Timolol Zolmitriptan may decrease the antihypertensive activities of Timolol. |
Verapamil | Verapamil The metabolism of Verapamil can be decreased when combined with Zolmitriptan. |
Atenolol | Atenolol Zolmitriptan may decrease the antihypertensive activities of Atenolol. |
Pindolol | Pindolol The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Pindolol. |
Diflunisal | Diflunisal The risk or severity of hypertension can be increased when Zolmitriptan is combined with Diflunisal. |
Piroxicam | Piroxicam The risk or severity of hypertension can be increased when Zolmitriptan is combined with Piroxicam. |
Streptozocin | Streptozocin The metabolism of Zolmitriptan can be increased when combined with Streptozocin. |
Etoposide | Etoposide The metabolism of Etoposide can be decreased when combined with Zolmitriptan. |
Indapamide | Indapamide Zolmitriptan may decrease the antihypertensive activities of Indapamide. |
Nafcillin Injection | Nafcillin Injection The metabolism of Zolmitriptan can be increased when combined with Nafcillin. |
Pentoxifylline | Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Zolmitriptan. |
Labetalol | Labetalol Zolmitriptan may decrease the antihypertensive activities of Labetalol. |
Gemfibrozil | Gemfibrozil The metabolism of Zolmitriptan can be decreased when combined with Gemfibrozil. |
Guanabenz | Guanabenz The metabolism of Guanabenz can be decreased when combined with Zolmitriptan. |
Ketoprofen | Ketoprofen The risk or severity of hypertension can be increased when Zolmitriptan is combined with Ketoprofen. |
Pimozide | Pimozide The metabolism of Pimozide can be decreased when combined with Zolmitriptan. |
Enalapril | Enalapril Zolmitriptan may decrease the antihypertensive activities of Enalapril. |
Flurbiprofen | Flurbiprofen The risk or severity of hypertension can be increased when Zolmitriptan is combined with Flurbiprofen. |
Amiodarone | Amiodarone The metabolism of Zolmitriptan can be decreased when combined with Amiodarone. |
Buspirone | Buspirone The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Buspirone. |
Ciprofloxacin | Ciprofloxacin The metabolism of Zolmitriptan can be decreased when combined with Ciprofloxacin. |
Mesalamine | Mesalamine The risk or severity of hypertension can be increased when Mesalazine is combined with Zolmitriptan. |
Diclofenac | Diclofenac The metabolism of Diclofenac can be decreased when combined with Zolmitriptan. |
Fluoxetine | Fluoxetine The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Fluoxetine. |
Nimodipine | Nimodipine Zolmitriptan may decrease the antihypertensive activities of Nimodipine. |
Interferon Alfa-2b Injection | Interferon Alfa-2b Injection The metabolism of Zolmitriptan can be decreased when combined with Interferon alfa-2b. |
Clozapine | Clozapine The metabolism of Zolmitriptan can be decreased when combined with Clozapine. |
Estazolam | Estazolam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Estazolam. |
Ofloxacin | Ofloxacin The metabolism of Zolmitriptan can be decreased when combined with Ofloxacin. |
Benazepril | Benazepril Zolmitriptan may decrease the antihypertensive activities of Benazepril. |
Etodolac | Etodolac The risk or severity of hypertension can be increased when Zolmitriptan is combined with Etodolac. |
Felodipine | Felodipine Zolmitriptan may decrease the antihypertensive activities of Felodipine. |
Fosinopril | Fosinopril Zolmitriptan may decrease the antihypertensive activities of Fosinopril. |
Nabumetone | Nabumetone The metabolism of Nabumetone can be decreased when combined with Zolmitriptan. |
Quinapril | Quinapril Zolmitriptan may decrease the antihypertensive activities of Quinapril. |
Ramipril | Ramipril Zolmitriptan may decrease the antihypertensive activities of Ramipril. |
Amlodipine | Amlodipine Zolmitriptan may decrease the antihypertensive activities of Amlodipine. |
Lisinopril | Lisinopril Zolmitriptan may decrease the antihypertensive activities of Lisinopril. |
Oxaprozin | Oxaprozin The risk or severity of hypertension can be increased when Zolmitriptan is combined with Oxaprozin. |
Bisoprolol | Bisoprolol Zolmitriptan may decrease the antihypertensive activities of Bisoprolol. |
Zolpidem | Zolpidem Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
Doxazosin | Doxazosin Zolmitriptan may decrease the antihypertensive activities of Doxazosin. |
Terazosin | Terazosin Zolmitriptan may decrease the antihypertensive activities of Terazosin. |
Isradipine | Isradipine Zolmitriptan may decrease the antihypertensive activities of Isradipine. |
Omeprazole | Omeprazole The metabolism of Zolmitriptan can be decreased when combined with Omeprazole. |
Cisapride | Cisapride The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Cisapride. |
Gabapentin | Gabapentin The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Gabapentin. |
Venlafaxine | Venlafaxine The risk or severity of serotonin syndrome can be increased when Venlafaxine is combined with Zolmitriptan. |
Fluvoxamine | Fluvoxamine The risk or severity of serotonin syndrome can be increased when Fluvoxamine is combined with Zolmitriptan. |
Nefazodone | Nefazodone The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Nefazodone. |
Lamotrigine | Lamotrigine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Lamotrigine. |
Losartan | Losartan Zolmitriptan may decrease the antihypertensive activities of Losartan. |
Tramadol | Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Zolmitriptan. |
Moexipril | Moexipril Zolmitriptan may decrease the antihypertensive activities of Moexipril. |
Nicardipine | Nicardipine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Nicardipine. |
Bupropion | Bupropion The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Bupropion. |
Ticlopidine | Ticlopidine The metabolism of Zolmitriptan can be decreased when combined with Ticlopidine. |
Nisoldipine | Nisoldipine Zolmitriptan may decrease the antihypertensive activities of Nisoldipine. |
Riluzole | Riluzole The metabolism of Riluzole can be decreased when combined with Zolmitriptan. |
Ritonavir | Ritonavir The metabolism of Zolmitriptan can be increased when combined with Ritonavir. |
Clomipramine | Clomipramine The metabolism of Clomipramine can be decreased when combined with Zolmitriptan. |
Zafirlukast | Zafirlukast The metabolism of Zolmitriptan can be decreased when combined with Zafirlukast. |
Mirtazapine | Mirtazapine Zolmitriptan may increase the serotonergic activities of Mirtazapine. |
Trandolapril | Trandolapril Zolmitriptan may decrease the antihypertensive activities of Trandolapril. |
Topiramate | Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Zolmitriptan. |
Zileuton | Zileuton The metabolism of Zileuton can be decreased when combined with Zolmitriptan. |
Valsartan | Valsartan Zolmitriptan may decrease the antihypertensive activities of Valsartan. |
Insulin Lispro Injection | Insulin Lispro Injection The metabolism of Zolmitriptan can be increased when combined with Insulin lispro. |
Pramipexole | Pramipexole Zolmitriptan may increase the sedative activities of Pramipexole. |
Donepezil | Donepezil The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Donepezil. |
Carvedilol | Carvedilol The metabolism of Carvedilol can be decreased when combined with Zolmitriptan. |
Flutamide | Flutamide The metabolism of Flutamide can be decreased when combined with Zolmitriptan. |
Selegiline | Selegiline The metabolism of Zolmitriptan can be decreased when combined with Selegiline. |
Sertraline | Sertraline The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Sertraline. |
Propafenone | Propafenone The metabolism of Zolmitriptan can be decreased when combined with Propafenone. |
Irbesartan | Irbesartan Zolmitriptan may decrease the antihypertensive activities of Irbesartan. |
Ropinirole | Ropinirole Zolmitriptan may increase the sedative activities of Ropinirole. |
Finasteride | Finasteride The risk or severity of hypertension can be increased when Zolmitriptan is combined with Finasteride. |
Quetiapine | Quetiapine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Quetiapine. |
Cetirizine | Cetirizine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Cetirizine. |
Paroxetine | Paroxetine The risk or severity of serotonin syndrome can be increased when Paroxetine is combined with Zolmitriptan. |
Tolcapone | Tolcapone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Tolcapone. |
Citalopram | Citalopram The risk or severity of serotonin syndrome can be increased when Citalopram is combined with Zolmitriptan. |
Efavirenz | Efavirenz The metabolism of Zolmitriptan can be decreased when combined with Efavirenz. |
Celecoxib | Celecoxib The risk or severity of hypertension can be increased when Zolmitriptan is combined with Celecoxib. |
Rosiglitazone | Rosiglitazone The metabolism of Zolmitriptan can be decreased when combined with Rosiglitazone. |
Tolterodine | Tolterodine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine. |
Thalidomide | Thalidomide Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
Balsalazide | Balsalazide The risk or severity of hypertension can be increased when Zolmitriptan is combined with Balsalazide. |
Levetiracetam | Levetiracetam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Levetiracetam. |
Rabeprazole | Rabeprazole The metabolism of Zolmitriptan can be increased when combined with Rabeprazole. |
Terbinafine | Terbinafine The metabolism of Terbinafine can be decreased when combined with Zolmitriptan. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists