Zolmitriptan

Generic name: Pronounced as (zohl mi trip' tan)
Brand names
  • Zomig-ZMT®
  • Zomig®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 01/15/2022

Zolmitriptan is used to treat the symptoms of migraine headaches (severe throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound and light). Zolmitriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels around the brain, stopping pain signals from being sent to the brain, and blocking the release of certain natural substances that cause pain, nausea, and other symptoms of migraine. Zolmitriptan does not prevent migraine attacks or reduce the number of headaches you have.

Zolmitriptan comes as a tablet and an orally disintegrating tablet (tablet that dissolves quickly in the mouth) to take by mouth. It is usually taken at the first sign of a migraine headache. If your symptoms improve after you take zolmitriptan but return after 2 hours or longer, you may take a second tablet. However, if your symptoms do not improve after you take zolmitriptan, do not take a second tablet without calling your doctor. Your doctor will tell you the maximum number of tablets or orally disintegrating tablets you may take in a 24-hour period. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take zolmitriptan exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

You may take your first dose of zolmitriptan in a doctor's office or other medical facility where you can be monitored for serious reactions.

If your doctor has prescribed a dose lower than 2.5 mg, you may use your fingers to break the 2.5-mg tablet on the line that divides it in half. However, you should not break or split the orally disintegrating tablet.

To take the orally disintegrating tablet, use dry hands to peel back the foil packaging. Immediately take out the tablet and place it on your tongue. The tablet will quickly dissolve and can be swallowed with saliva. No water is needed to swallow disintegrating tablets. Do not open the foil packaging or remove the orally disintegrating tablet until just before you are ready to take it.

Call your doctor if your headaches do not get better or occur more frequently after taking zolmitriptan.

If you take zolmitriptan more often or for longer than the recommended period of time, your headaches may get worse or may occur more frequently. You should not take zolmitriptan or any other headache medication for more than 10 days per month. Call your doctor if you need to take zolmitriptan to treat more than three headaches in a 1-month period.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking zolmitriptan,

  • tell your doctor and pharmacist if you are allergic to zolmitriptan, any other medications, or any of the ingredients in zolmitriptan tablets or orally disintegrating tablets. Ask your pharmacist for a list of the ingredients.

  • do not take zolmitriptan if you have taken any of the following medications in the past 24 hours: other selective serotonin receptor agonists such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), or sumatriptan (Imitrex, in Treximet); or ergot-type medications such as bromocriptine (Parlodel), cabergoline , dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Hydergine), ergonovine (Ergotrate), ergotamine (Cafergot, Ergomar, Wigraine), methylergonovine (Methergine), methysergide (Sansert), and pergolide (Permax).

  • do not take zolmitriptan if you are taking a monoamine oxidase A (MAO-A) inhibitor such as isocarboxazid (Marplan), phenelzine (Parnate), or tranylcypromine (Nardil) or if you have taken one of these medications in the past 2 weeks.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, or herbal products you are taking or plan to take. Be sure to mention any of the following: acetaminophen (Tylenol); antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); cimetidine (Tagamet); oral contraceptives ('birth control pills'); propranolol (Inderal); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft); and selective serotonin/norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Pristiq), duloxetine (Cymbalta), sibutramine (Meridia), and venlafaxine (Effexor). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have or have ever had heart disease; a heart attack; angina (chest pain); irregular heartbeats; stroke or 'mini-stroke'; or circulation problems such as varicose veins, blood clots in the legs, Raynaud's disease (problems with blood flow to the fingers, toes, ears, and nose), or ischemic bowel disease (bloody diarrhea and stomach pain caused by decreased blood flow to the intestines). Your doctor may tell you not to take zolmitriptan.

  • tell your doctor if you smoke or are overweight; if you have or have ever had high blood pressure, high cholesterol, diabetes, or liver or kidney disease; if you have gone through menopause (change of life); or if any family members have or have ever had heart disease or stroke.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you plan to be sexually active while you are taking this medication, talk to your doctor about effective methods of birth control. If you become pregnant while taking zolmitriptan, call your doctor.

  • you should know that this medication may make you drowsy or dizzy. Do not drive a car or operate machinery until you know how zolmitriptan affects you.

  • talk to your doctor about your headache symptoms to make sure they are caused by migraine. Zolmitriptan should not be used to treat certain types of migraine headaches (hemiplegic or basilar) or other types of headaches (such as cluster headaches).

  • if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent damage to your brain that can cause severe intellectual disability), you should know that the orally disintegrating tablets contain aspartame that forms phenylalanine.

Unless your doctor tells you otherwise, continue your normal diet.

  • Zolmitriptan may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • feeling warm or cold

    • drowsiness

    • dry mouth

    • nausea

    • heartburn

    • sweating

    • dizziness or faintness

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

    • pain, tightness, pressure, or heaviness in the chest, throat, neck, or jaw

    • slow or difficult speech

    • weakness or numbness of an arm or leg

    • fast, pounding, or irregular heartbeat

    • bloody diarrhea

    • sudden or severe stomach pain

    • paleness or blue color of the fingers and toes

    • shortness of breath

    • swelling of the eyes, face, lips, tongue, or throat

    • difficulty breathing or swallowing

    • hoarseness

    • rash

    • hives

    • pain, burning, or tingling in the hands or feet

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat, and moisture (not in the bathroom). Dispose of any orally disintegrating tablets that you removed from the blister pack but did not use immediately.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

  • extreme drowsiness

Keep all appointments with your doctor. Your blood pressure should be checked regularly.

You should keep a headache diary by writing down when you have headaches and when you take zolmitriptan.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The metabolism of Zolmitriptan can be decreased when combined with Moxifloxacin.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection The metabolism of Zolmitriptan can be increased when combined with Insulin glargine.
Leflunomide Leflunomide The serum concentration of Zolmitriptan can be decreased when it is combined with Leflunomide.
Nevirapine Nevirapine The metabolism of Zolmitriptan can be decreased when combined with Nevirapine.
Dolasetron Dolasetron The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Dolasetron.
Aminophylline Aminophylline The metabolism of Aminophylline can be decreased when combined with Zolmitriptan.
Anagrelide Anagrelide The metabolism of Zolmitriptan can be decreased when combined with Anagrelide.
Candesartan Candesartan Zolmitriptan may decrease the antihypertensive activities of Candesartan.
Cilostazol Cilostazol The metabolism of Cilostazol can be decreased when combined with Zolmitriptan.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Zolmitriptan.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Diphenoxylate.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The metabolism of Zolmitriptan can be decreased when combined with Conjugated estrogens.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Guanfacine.
Methylergonovine Methylergonovine Methylergometrine may increase the vasoconstricting activities of Zolmitriptan.
Naratriptan Naratriptan The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Naratriptan.
Olsalazine Olsalazine The risk or severity of hypertension can be increased when Zolmitriptan is combined with Olsalazine.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Zolmitriptan.
Penbutolol Penbutolol Zolmitriptan may decrease the antihypertensive activities of Acebutolol.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Pentazocine.
Ranitidine Ranitidine The metabolism of Zolmitriptan can be decreased when combined with Ranitidine.
Reserpine Reserpine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Reserpine.
Rizatriptan Rizatriptan The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Sumatriptan.
Tizanidine Tizanidine The metabolism of Tizanidine can be decreased when combined with Zolmitriptan.
Famotidine Injection Famotidine Injection The metabolism of Zolmitriptan can be decreased when combined with Famotidine.
Hydromorphone Injection Hydromorphone Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Hydromorphone.
Interferon Beta-1b Injection Interferon Beta-1b Injection The metabolism of Zolmitriptan can be decreased when combined with Interferon beta-1b.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The metabolism of Zolmitriptan can be decreased when combined with Interferon gamma-1b.
Levofloxacin Injection Levofloxacin Injection The metabolism of Zolmitriptan can be decreased when combined with Levofloxacin.
Meperidine Injection Meperidine Injection The metabolism of Zolmitriptan can be increased when combined with Meperidine.
Metoclopramide Injection Metoclopramide Injection The risk or severity of sedation can be increased when Zolmitriptan is combined with Metoclopramide.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Zolmitriptan.
Altretamine Altretamine The metabolism of Zolmitriptan can be decreased when combined with Amphetamine.
Cyclosporine Cyclosporine The risk or severity of hypertension can be increased when Cyclosporine is combined with Zolmitriptan.
Ondansetron Ondansetron The metabolism of Zolmitriptan can be decreased when combined with Ondansetron.
Granisetron Granisetron The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Granisetron.
Torsemide Torsemide Zolmitriptan may decrease the antihypertensive activities of Torasemide.
Olanzapine Olanzapine The metabolism of Olanzapine can be decreased when combined with Zolmitriptan.
Alosetron Alosetron The metabolism of Zolmitriptan can be decreased when combined with Alosetron.
Entacapone Entacapone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Entacapone.
Eprosartan Eprosartan Zolmitriptan may decrease the antihypertensive activities of Eprosartan.
Meloxicam Meloxicam The risk or severity of hypertension can be increased when Zolmitriptan is combined with Meloxicam.
Oxcarbazepine Oxcarbazepine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Oxcarbazepine.
Telmisartan Telmisartan Zolmitriptan may decrease the antihypertensive activities of Telmisartan.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Zaleplon.
Anakinra Anakinra The metabolism of Zolmitriptan can be increased when combined with Anakinra.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Desloratadine.
Linezolid Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Zolmitriptan.
Trimipramine Trimipramine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Trimipramine.
Etanercept Injection Etanercept Injection The metabolism of Zolmitriptan can be increased when combined with Etanercept.
Glycopyrrolate Glycopyrrolate Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Modafinil Modafinil The metabolism of Zolmitriptan can be increased when combined with Modafinil.
Perindopril Perindopril Zolmitriptan may decrease the antihypertensive activities of Perindopril.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate The risk or severity of hypertension can be increased when Zolmitriptan is combined with Choline magnesium trisalicylate.
Dutasteride Dutasteride The risk or severity of hypertension can be increased when Zolmitriptan is combined with Dutasteride.
Epinephrine Injection Epinephrine Injection The risk or severity of hypertension can be increased when Zolmitriptan is combined with Epinephrine.
Eplerenone Eplerenone Zolmitriptan may decrease the antihypertensive activities of Eplerenone.
Escitalopram Escitalopram The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Escitalopram.
Olmesartan Olmesartan Zolmitriptan may decrease the antihypertensive activities of Olmesartan.
Zonisamide Zonisamide The metabolism of Zolmitriptan can be decreased when combined with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Zolmitriptan can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Aripiprazole.
Atomoxetine Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Zolmitriptan.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Dexmethylphenidate.
Almotriptan Almotriptan The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Almotriptan.
Eletriptan Eletriptan The risk or severity of vasospastic reactions can be increased when Eletriptan is combined with Zolmitriptan.
Interferon Beta-1a Subcutaneous Injection Interferon Beta-1a Subcutaneous Injection The metabolism of Zolmitriptan can be decreased when combined with Interferon beta-1a.
Tegaserod Tegaserod The metabolism of Zolmitriptan can be decreased when combined with Tegaserod.
Tadalafil Tadalafil Zolmitriptan may decrease the antihypertensive activities of Tadalafil.
Frovatriptan Frovatriptan The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Frovatriptan.
Gemifloxacin Gemifloxacin The metabolism of Zolmitriptan can be decreased when combined with Gemifloxacin.
Apomorphine Injection Apomorphine Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Apomorphine.
Infliximab Injection Infliximab Injection The metabolism of Zolmitriptan can be increased when combined with Infliximab.
Protriptyline Protriptyline The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Protriptyline.
Duloxetine Duloxetine The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Duloxetine.
Trospium Trospium Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Bosentan Bosentan Zolmitriptan may decrease the antihypertensive activities of Bosentan.
Cinacalcet Cinacalcet The metabolism of Cinacalcet can be decreased when combined with Zolmitriptan.
Erlotinib Erlotinib The metabolism of Erlotinib can be decreased when combined with Zolmitriptan.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Eszopiclone.
Solifenacin Solifenacin Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Dextroamphetamine Dextroamphetamine The metabolism of Zolmitriptan can be decreased when combined with Amphetamine.
Entecavir Entecavir The metabolism of Entecavir can be decreased when combined with Zolmitriptan.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The metabolism of Zolmitriptan can be decreased when combined with Peginterferon alfa-2a.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Zolmitriptan can be decreased when combined with Peginterferon alfa-2b.
Sodium Oxybate Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan.
Isocarboxazid Isocarboxazid The metabolism of Zolmitriptan can be decreased when combined with Isocarboxazid.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Zolmitriptan.
Darifenacin Darifenacin Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Darifenacin.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Fentanyl.
Pregabalin Pregabalin The therapeutic efficacy of Zolmitriptan can be increased when used in combination with Pregabalin.
Deferasirox Deferasirox The metabolism of Zolmitriptan can be decreased when combined with Deferasirox.
Phenylephrine Phenylephrine The metabolism of Zolmitriptan can be increased when combined with Phenylephrine.
Felbamate Felbamate The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Felbamate.
Abatacept Injection Abatacept Injection The metabolism of Zolmitriptan can be increased when combined with Abatacept.
Rasagiline Rasagiline The metabolism of Zolmitriptan can be decreased when combined with Rasagiline.
Imatinib Imatinib The metabolism of Imatinib can be decreased when combined with Zolmitriptan.
Albuterol Albuterol The risk or severity of hypertension can be increased when Zolmitriptan is combined with Salbutamol.
Paliperidone Paliperidone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Paliperidone.
Bortezomib Bortezomib The metabolism of Zolmitriptan can be decreased when combined with Bortezomib.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection The metabolism of Zolmitriptan can be increased when combined with Insulin glulisine.
Primaquine Primaquine The metabolism of Zolmitriptan can be increased when combined with Primaquine.
Aliskiren Aliskiren Zolmitriptan may decrease the antihypertensive activities of Aliskiren.
Pemetrexed Injection Pemetrexed Injection The metabolism of Pemetrexed can be decreased when combined with Zolmitriptan.
Dimenhydrinate Dimenhydrinate The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Dimenhydrinate.
Lisdexamfetamine Lisdexamfetamine The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Lisdexamfetamine.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan.
Sorafenib Sorafenib The metabolism of Sorafenib can be decreased when combined with Zolmitriptan.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Levocetirizine.
Dasatinib Dasatinib The metabolism of Dasatinib can be decreased when combined with Zolmitriptan.
Mexiletine Mexiletine The metabolism of Zolmitriptan can be decreased when combined with Mexiletine.
Armodafinil Armodafinil The metabolism of Zolmitriptan can be increased when combined with Armodafinil.
Desmopressin Desmopressin The risk or severity of hypertension can be increased when Desmopressin is combined with Zolmitriptan.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Zolmitriptan.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Zolmitriptan.
Desvenlafaxine Desvenlafaxine The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Desvenlafaxine.
Nebivolol Nebivolol Zolmitriptan may decrease the antihypertensive activities of Nebivolol.
Bendamustine Injection Bendamustine Injection The metabolism of Bendamustine can be decreased when combined with Zolmitriptan.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Zolmitriptan.
Certolizumab Injection Certolizumab Injection The metabolism of Zolmitriptan can be increased when combined with Certolizumab pegol.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Zolmitriptan.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Zolmitriptan.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Midazolam.
Naltrexone Injection Naltrexone Injection The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Naltrexone.
Eltrombopag Eltrombopag The metabolism of Eltrombopag can be decreased when combined with Zolmitriptan.
Milnacipran Milnacipran The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Milnacipran.
Fesoterodine Fesoterodine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Betaxolol Betaxolol The metabolism of Zolmitriptan can be decreased when combined with Betaxolol.
Iloperidone Iloperidone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Iloperidone.
Lacosamide Lacosamide The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Lacosamide.
Dronedarone Dronedarone The risk or severity of hypertension can be increased when Zolmitriptan is combined with Dronedarone.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Zolmitriptan.
Palonosetron Injection Palonosetron Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Palonosetron.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan.
Golimumab Injection Golimumab Injection The metabolism of Zolmitriptan can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Pazopanib can be decreased when combined with Zolmitriptan.
Asenapine Asenapine The metabolism of Asenapine can be decreased when combined with Zolmitriptan.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Vigabatrin.
Albendazole Albendazole The metabolism of Albendazole can be decreased when combined with Zolmitriptan.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Oxymorphone.
Tocilizumab Injection Tocilizumab Injection The metabolism of Zolmitriptan can be increased when combined with Tocilizumab.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Zolmitriptan.
Lurasidone Lurasidone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Lurasidone.
Acetaminophen Injection Acetaminophen Injection The metabolism of Acetaminophen can be decreased when combined with Zolmitriptan.
Vilazodone Vilazodone The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Vilazodone.
Terbutaline Injection Terbutaline Injection The risk or severity of hypertension can be increased when Zolmitriptan is combined with Terbutaline.
Telaprevir Telaprevir The metabolism of Zolmitriptan can be decreased when combined with Glecaprevir.
Abiraterone Abiraterone The metabolism of Zolmitriptan can be decreased when combined with Abiraterone.
Clobazam Clobazam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Clobazam.
Vemurafenib Vemurafenib The serum concentration of Zolmitriptan can be increased when it is combined with Vemurafenib.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Zolmitriptan.
Cabergoline Cabergoline The risk or severity of vasospastic reactions can be increased when Cabergoline is combined with Zolmitriptan.
Ambrisentan Ambrisentan Zolmitriptan may decrease the antihypertensive activities of Ambrisentan.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Tiagabine.
Mirabegron Mirabegron The risk or severity of hypertension can be increased when Zolmitriptan is combined with Mirabegron.
Teriflunomide Teriflunomide The serum concentration of Zolmitriptan can be decreased when it is combined with Teriflunomide.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Zolmitriptan.
Levomilnacipran Levomilnacipran The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Levomilnacipran.
Vortioxetine Vortioxetine The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Vortioxetine.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan.
Ketorolac Injection Ketorolac Injection The risk or severity of hypertension can be increased when Zolmitriptan is combined with Ketorolac.
Simeprevir Simeprevir The metabolism of Zolmitriptan can be decreased when combined with Simeprevir.
Dapagliflozin Dapagliflozin The metabolism of Zolmitriptan can be decreased when combined with Dapagliflozin.
Apremilast Apremilast The metabolism of Zolmitriptan can be increased when combined with Apremilast.
Droxidopa Droxidopa Zolmitriptan may increase the hypertensive activities of Droxidopa.
Siltuximab Injection Siltuximab Injection The metabolism of Zolmitriptan can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Eslicarbazepine.
Belinostat Injection Belinostat Injection The metabolism of Zolmitriptan can be increased when combined with Belinostat.
Hydrocodone Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan.
Suvorexant Suvorexant Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The metabolism of Zolmitriptan can be decreased when combined with Peginterferon beta-1a.
Methamphetamine Methamphetamine The metabolism of Zolmitriptan can be decreased when combined with Metamfetamine.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Zolmitriptan.
Riociguat Riociguat Zolmitriptan may decrease the antihypertensive activities of Riociguat.
Pirfenidone Pirfenidone The metabolism of Zolmitriptan can be decreased when combined with Pirfenidone.
Secukinumab Injection Secukinumab Injection The metabolism of Zolmitriptan can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Risperidone.
Insulin Human Inhalation Insulin Human Inhalation The metabolism of Zolmitriptan can be increased when combined with Insulin human.
Lenvatinib Lenvatinib The metabolism of Zolmitriptan can be decreased when combined with Lenvatinib.
Haloperidol Injection Haloperidol Injection The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Haloperidol.
Macitentan Macitentan Zolmitriptan may decrease the antihypertensive activities of Macitentan.
Flibanserin Flibanserin The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Flibanserin.
Brexpiprazole Brexpiprazole The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Ziprasidone.
Cariprazine Cariprazine The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Cariprazine.
Eluxadoline Eluxadoline The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Eluxadoline.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection The metabolism of Zolmitriptan can be increased when combined with Insulin degludec.
Osimertinib Osimertinib The serum concentration of Zolmitriptan can be decreased when it is combined with Osimertinib.
Brivaracetam Injection Brivaracetam Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Brivaracetam.
Midodrine Midodrine The risk or severity of hypertension can be increased when Midodrine is combined with Zolmitriptan.
Selexipag Selexipag Zolmitriptan may decrease the antihypertensive activities of Selexipag.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Pimavanserin.
Obeticholic Acid Obeticholic Acid The metabolism of Zolmitriptan can be decreased when combined with Obeticholic acid.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Diphenhydramine.
Furosemide Injection Furosemide Injection Zolmitriptan may decrease the antihypertensive activities of Furosemide.
Rucaparib Rucaparib The metabolism of Zolmitriptan can be decreased when combined with Rucaparib.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Zolmitriptan.
Safinamide Safinamide The metabolism of Zolmitriptan can be decreased when combined with Safinamide.
Midostaurin Midostaurin The metabolism of Zolmitriptan can be decreased when combined with Midostaurin.
Enasidenib Enasidenib The metabolism of Zolmitriptan can be decreased when combined with Enasidenib.
Buprenorphine Injection Buprenorphine Injection Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Lofexidine Lofexidine The therapeutic efficacy of Zolmitriptan can be increased when used in combination with Lofexidine.
Binimetinib Binimetinib The metabolism of Binimetinib can be decreased when combined with Zolmitriptan.
Cannabidiol Cannabidiol The risk or severity of vasospastic reactions can be increased when Cannabidiol is combined with Zolmitriptan.
Stiripentol Stiripentol The metabolism of Zolmitriptan can be decreased when combined with Stiripentol.
Gilteritinib Gilteritinib The therapeutic efficacy of Zolmitriptan can be decreased when used in combination with Gilteritinib.
Rifamycin Rifamycin The metabolism of Zolmitriptan can be decreased when combined with Rifamycin.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Zolmitriptan can be increased when combined with Emapalumab.
Siponimod Siponimod The risk or severity of hypertension can be increased when Zolmitriptan is combined with Siponimod.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Acyclovir can be decreased when combined with Zolmitriptan.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Brexanolone.
Solriamfetol Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Zolmitriptan.
Triclabendazole Triclabendazole The metabolism of Zolmitriptan can be decreased when combined with Triclabendazole.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Zolmitriptan.
Pitolisant Pitolisant The metabolism of Zolmitriptan can be increased when combined with Pitolisant.
Phenytoin Injection Phenytoin Injection The risk or severity of adverse effects can be increased when Phenytoin is combined with Zolmitriptan.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Zolmitriptan can be increased when combined with Fosphenytoin.
Lumateperone Lumateperone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Lumateperone.
Lasmiditan Lasmiditan The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Lasmiditan.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Zolmitriptan.
Selpercatinib Selpercatinib The risk or severity of hypertension can be increased when Zolmitriptan is combined with Selpercatinib.
Capmatinib Capmatinib The metabolism of Zolmitriptan can be decreased when combined with Capmatinib.
Lemborexant Lemborexant The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Lemborexant.
Fenfluramine Fenfluramine The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Fenfluramine.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Zolmitriptan can be decreased when it is combined with Satralizumab.
Naxitamab-gqgk Injection Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Zolmitriptan is combined with Naxitamab.
Viloxazine Viloxazine The metabolism of Zolmitriptan can be decreased when combined with Viloxazine.
Theophylline Theophylline The metabolism of Zolmitriptan can be decreased when combined with Theophylline.
Fenoprofen Fenoprofen The risk or severity of hypertension can be increased when Zolmitriptan is combined with Fenoprofen.
Indomethacin Indomethacin The risk or severity of hypertension can be increased when Zolmitriptan is combined with Indomethacin.
Mefenamic Acid Mefenamic Acid The risk or severity of hypertension can be increased when Zolmitriptan is combined with Mefenamic acid.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Zolmitriptan.
Tolmetin Tolmetin The risk or severity of hypertension can be increased when Zolmitriptan is combined with Tolmetin.
Sulindac Sulindac The risk or severity of hypertension can be increased when Zolmitriptan is combined with Sulindac.
Trazodone Trazodone The risk or severity of serotonin syndrome can be increased when Trazodone is combined with Zolmitriptan.
Phenobarbital Phenobarbital The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Phenobarbital.
Metaxalone Metaxalone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Metaxalone.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Levorphanol.
Primidone Primidone The metabolism of Zolmitriptan can be increased when combined with Primidone.
Methsuximide Methsuximide The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Methsuximide.
Diethylpropion Diethylpropion The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Diethylpropion.
Chlorpromazine Chlorpromazine The metabolism of Chlorpromazine can be decreased when combined with Zolmitriptan.
Diazepam Diazepam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Diazepam.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Oxazepam.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Flurazepam.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Clorazepic acid.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Zolmitriptan.
Phenoxybenzamine Phenoxybenzamine The risk or severity of hypertension can be increased when Zolmitriptan is combined with Phenoxybenzamine.
Carmustine Carmustine The metabolism of Zolmitriptan can be decreased when combined with Carmustine.
Amantadine Amantadine The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Amantadine.
Codeine Codeine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Codeine.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Meprobamate.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Chlordiazepoxide.
Bromocriptine Bromocriptine Bromocriptine may increase the vasoconstricting activities of Zolmitriptan.
Metaproterenol Metaproterenol The risk or severity of hypertension can be increased when Zolmitriptan is combined with Orciprenaline.
Tranylcypromine Tranylcypromine The metabolism of Zolmitriptan can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Zolmitriptan can be decreased when combined with Phenelzine.
Procarbazine Procarbazine The metabolism of Zolmitriptan can be decreased when combined with Procarbazine.
Ergoloid Mesylates Ergoloid Mesylates Ergoloid mesylate may increase the vasoconstricting activities of Zolmitriptan.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan.
Prochlorperazine Prochlorperazine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Prochlorperazine.
Thioridazine Thioridazine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Thioridazine.
Trifluoperazine Trifluoperazine The metabolism of Trifluoperazine can be decreased when combined with Zolmitriptan.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Oxycodone.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Zolmitriptan.
Oxybutynin Oxybutynin Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin.
Benztropine Benztropine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Benzatropine.
Maprotiline Maprotiline The metabolism of Maprotiline can be decreased when combined with Zolmitriptan.
Ibuprofen Ibuprofen The risk or severity of hypertension can be increased when Zolmitriptan is combined with Ibuprofen.
Trihexyphenidyl Trihexyphenidyl Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine Orphenadrine The metabolism of Zolmitriptan can be decreased when combined with Orphenadrine.
Perphenazine Perphenazine The metabolism of Perphenazine can be decreased when combined with Zolmitriptan.
Azathioprine Azathioprine The metabolism of Azathioprine can be decreased when combined with Zolmitriptan.
Fluphenazine Fluphenazine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Fluphenazine.
Phentermine Phentermine The metabolism of Zolmitriptan can be decreased when combined with Phentermine.
Methylphenidate Methylphenidate The risk or severity of hypertension can be increased when Zolmitriptan is combined with Methylphenidate.
Amoxapine Amoxapine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Amoxapine.
Sulfasalazine Sulfasalazine The risk or severity of hypertension can be increased when Zolmitriptan is combined with Sulfasalazine.
Carbamazepine Carbamazepine The metabolism of Zolmitriptan can be decreased when combined with Carbamazepine.
Molindone Molindone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Molindone.
Methyldopa Methyldopa Zolmitriptan may decrease the antihypertensive activities of Methyldopa.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Zolmitriptan.
Prazosin Prazosin Zolmitriptan may decrease the antihypertensive activities of Prazosin.
Hydralazine Hydralazine Zolmitriptan may decrease the antihypertensive activities of Hydralazine.
Cimetidine Cimetidine The serum concentration of Zolmitriptan can be increased when it is combined with Cimetidine.
Warfarin Warfarin The metabolism of Warfarin can be decreased when combined with Zolmitriptan.
Clonazepam Clonazepam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Clonazepam.
Promethazine Promethazine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Promethazine.
Meclofenamate Meclofenamate The risk or severity of hypertension can be increased when Zolmitriptan is combined with Meclofenamic acid.
Griseofulvin Griseofulvin The metabolism of Zolmitriptan can be increased when combined with Griseofulvin.
Loxapine Loxapine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Loxapine.
Quinine Quinine The metabolism of Quinine can be decreased when combined with Zolmitriptan.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Ethosuximide.
Triamterene Triamterene The metabolism of Triamterene can be decreased when combined with Zolmitriptan.
Chlorothiazide Chlorothiazide Zolmitriptan may decrease the antihypertensive activities of Chlorothiazide.
Chlorthalidone Chlorthalidone Zolmitriptan may decrease the antihypertensive activities of Chlorthalidone.
Metolazone Metolazone Zolmitriptan may decrease the antihypertensive activities of Metolazone.
Secobarbital Secobarbital The metabolism of Zolmitriptan can be increased when combined with Secobarbital.
Desipramine Desipramine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Desipramine.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Zolmitriptan.
Imipramine Imipramine The metabolism of Zolmitriptan can be decreased when combined with Imipramine.
Quinidine Quinidine The metabolism of Zolmitriptan can be decreased when combined with Quinidine.
Isoniazid Isoniazid The metabolism of Zolmitriptan can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Zolmitriptan can be increased when combined with Rifampicin.
Disopyramide Disopyramide The metabolism of Zolmitriptan can be decreased when combined with Disopyramide.
Valproic Acid Valproic Acid The metabolism of Zolmitriptan can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Zolmitriptan.
Butabarbital Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Zolmitriptan.
Methimazole Methimazole The metabolism of Zolmitriptan can be decreased when combined with Methimazole.
Dextromethorphan Dextromethorphan The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Dextromethorphan.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Cyclobenzaprine.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Zolmitriptan.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan.
Cyproheptadine Cyproheptadine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Cyproheptadine.
Clemastine Clemastine The risk or severity of adverse effects can be increased when Clemastine is combined with Zolmitriptan.
Chlorpheniramine Chlorpheniramine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Dexbrompheniramine.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Meclizine.
Hydrochlorothiazide Hydrochlorothiazide Zolmitriptan may decrease the antihypertensive activities of Hydrochlorothiazide.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Zolmitriptan.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Zolmitriptan.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Methocarbamol.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The serum concentration of the active metabolites of Zolmitriptan can be reduced when Zolmitriptan is used in combination with Propranolol resulting in a loss in efficacy.
Minoxidil Minoxidil Zolmitriptan may decrease the antihypertensive activities of Minoxidil.
Pseudoephedrine Pseudoephedrine The metabolism of Zolmitriptan can be decreased when combined with Pseudoephedrine.
Nortriptyline Nortriptyline Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Nortriptyline.
Nadolol Nadolol Zolmitriptan may decrease the antihypertensive activities of Nadolol.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Butorphanol.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Nalbuphine.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Trimethobenzamide.
Flavoxate Flavoxate Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Zolmitriptan.
Dacarbazine Dacarbazine The metabolism of Dacarbazine can be decreased when combined with Zolmitriptan.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Acetazolamide.
Ketoconazole Ketoconazole The metabolism of Zolmitriptan can be decreased when combined with Ketoconazole.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Pyrantel.
Captopril Captopril Zolmitriptan may decrease the antihypertensive activities of Captopril.
Isoxsuprine Isoxsuprine The risk or severity of hypertension can be increased when Zolmitriptan is combined with Isoxsuprine.
Metoprolol Metoprolol Zolmitriptan may decrease the antihypertensive activities of Metoprolol.
Hydroxyzine Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Zolmitriptan.
Thiothixene Thiothixene The metabolism of Thiothixene can be decreased when combined with Zolmitriptan.
Aspirin Aspirin The risk or severity of hypertension can be increased when Zolmitriptan is combined with Acetylsalicylic acid.
Salsalate Salsalate The risk or severity of hypertension can be increased when Zolmitriptan is combined with Salsalate.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Alprazolam.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Zolmitriptan.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Triazolam.
Dicyclomine Dicyclomine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine Hyoscyamine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline Propantheline Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Diltiazem Diltiazem Zolmitriptan may decrease the antihypertensive activities of Diltiazem.
Nifedipine Nifedipine The metabolism of Nifedipine can be decreased when combined with Zolmitriptan.
Timolol Timolol Zolmitriptan may decrease the antihypertensive activities of Timolol.
Verapamil Verapamil The metabolism of Verapamil can be decreased when combined with Zolmitriptan.
Atenolol Atenolol Zolmitriptan may decrease the antihypertensive activities of Atenolol.
Pindolol Pindolol The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Pindolol.
Diflunisal Diflunisal The risk or severity of hypertension can be increased when Zolmitriptan is combined with Diflunisal.
Piroxicam Piroxicam The risk or severity of hypertension can be increased when Zolmitriptan is combined with Piroxicam.
Streptozocin Streptozocin The metabolism of Zolmitriptan can be increased when combined with Streptozocin.
Etoposide Etoposide The metabolism of Etoposide can be decreased when combined with Zolmitriptan.
Indapamide Indapamide Zolmitriptan may decrease the antihypertensive activities of Indapamide.
Nafcillin Injection Nafcillin Injection The metabolism of Zolmitriptan can be increased when combined with Nafcillin.
Pentoxifylline Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Zolmitriptan.
Labetalol Labetalol Zolmitriptan may decrease the antihypertensive activities of Labetalol.
Gemfibrozil Gemfibrozil The metabolism of Zolmitriptan can be decreased when combined with Gemfibrozil.
Guanabenz Guanabenz The metabolism of Guanabenz can be decreased when combined with Zolmitriptan.
Ketoprofen Ketoprofen The risk or severity of hypertension can be increased when Zolmitriptan is combined with Ketoprofen.
Pimozide Pimozide The metabolism of Pimozide can be decreased when combined with Zolmitriptan.
Enalapril Enalapril Zolmitriptan may decrease the antihypertensive activities of Enalapril.
Flurbiprofen Flurbiprofen The risk or severity of hypertension can be increased when Zolmitriptan is combined with Flurbiprofen.
Amiodarone Amiodarone The metabolism of Zolmitriptan can be decreased when combined with Amiodarone.
Buspirone Buspirone The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Buspirone.
Ciprofloxacin Ciprofloxacin The metabolism of Zolmitriptan can be decreased when combined with Ciprofloxacin.
Mesalamine Mesalamine The risk or severity of hypertension can be increased when Mesalazine is combined with Zolmitriptan.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Zolmitriptan.
Fluoxetine Fluoxetine The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Fluoxetine.
Nimodipine Nimodipine Zolmitriptan may decrease the antihypertensive activities of Nimodipine.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The metabolism of Zolmitriptan can be decreased when combined with Interferon alfa-2b.
Clozapine Clozapine The metabolism of Zolmitriptan can be decreased when combined with Clozapine.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Estazolam.
Ofloxacin Ofloxacin The metabolism of Zolmitriptan can be decreased when combined with Ofloxacin.
Benazepril Benazepril Zolmitriptan may decrease the antihypertensive activities of Benazepril.
Etodolac Etodolac The risk or severity of hypertension can be increased when Zolmitriptan is combined with Etodolac.
Felodipine Felodipine Zolmitriptan may decrease the antihypertensive activities of Felodipine.
Fosinopril Fosinopril Zolmitriptan may decrease the antihypertensive activities of Fosinopril.
Nabumetone Nabumetone The metabolism of Nabumetone can be decreased when combined with Zolmitriptan.
Quinapril Quinapril Zolmitriptan may decrease the antihypertensive activities of Quinapril.
Ramipril Ramipril Zolmitriptan may decrease the antihypertensive activities of Ramipril.
Amlodipine Amlodipine Zolmitriptan may decrease the antihypertensive activities of Amlodipine.
Lisinopril Lisinopril Zolmitriptan may decrease the antihypertensive activities of Lisinopril.
Oxaprozin Oxaprozin The risk or severity of hypertension can be increased when Zolmitriptan is combined with Oxaprozin.
Bisoprolol Bisoprolol Zolmitriptan may decrease the antihypertensive activities of Bisoprolol.
Zolpidem Zolpidem Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin Doxazosin Zolmitriptan may decrease the antihypertensive activities of Doxazosin.
Terazosin Terazosin Zolmitriptan may decrease the antihypertensive activities of Terazosin.
Isradipine Isradipine Zolmitriptan may decrease the antihypertensive activities of Isradipine.
Omeprazole Omeprazole The metabolism of Zolmitriptan can be decreased when combined with Omeprazole.
Cisapride Cisapride The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Cisapride.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Gabapentin.
Venlafaxine Venlafaxine The risk or severity of serotonin syndrome can be increased when Venlafaxine is combined with Zolmitriptan.
Fluvoxamine Fluvoxamine The risk or severity of serotonin syndrome can be increased when Fluvoxamine is combined with Zolmitriptan.
Nefazodone Nefazodone The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Nefazodone.
Lamotrigine Lamotrigine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Lamotrigine.
Losartan Losartan Zolmitriptan may decrease the antihypertensive activities of Losartan.
Tramadol Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Zolmitriptan.
Moexipril Moexipril Zolmitriptan may decrease the antihypertensive activities of Moexipril.
Nicardipine Nicardipine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Nicardipine.
Bupropion Bupropion The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Bupropion.
Ticlopidine Ticlopidine The metabolism of Zolmitriptan can be decreased when combined with Ticlopidine.
Nisoldipine Nisoldipine Zolmitriptan may decrease the antihypertensive activities of Nisoldipine.
Riluzole Riluzole The metabolism of Riluzole can be decreased when combined with Zolmitriptan.
Ritonavir Ritonavir The metabolism of Zolmitriptan can be increased when combined with Ritonavir.
Clomipramine Clomipramine The metabolism of Clomipramine can be decreased when combined with Zolmitriptan.
Zafirlukast Zafirlukast The metabolism of Zolmitriptan can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine Zolmitriptan may increase the serotonergic activities of Mirtazapine.
Trandolapril Trandolapril Zolmitriptan may decrease the antihypertensive activities of Trandolapril.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Zolmitriptan.
Zileuton Zileuton The metabolism of Zileuton can be decreased when combined with Zolmitriptan.
Valsartan Valsartan Zolmitriptan may decrease the antihypertensive activities of Valsartan.
Insulin Lispro Injection Insulin Lispro Injection The metabolism of Zolmitriptan can be increased when combined with Insulin lispro.
Pramipexole Pramipexole Zolmitriptan may increase the sedative activities of Pramipexole.
Donepezil Donepezil The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Donepezil.
Carvedilol Carvedilol The metabolism of Carvedilol can be decreased when combined with Zolmitriptan.
Flutamide Flutamide The metabolism of Flutamide can be decreased when combined with Zolmitriptan.
Selegiline Selegiline The metabolism of Zolmitriptan can be decreased when combined with Selegiline.
Sertraline Sertraline The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Sertraline.
Propafenone Propafenone The metabolism of Zolmitriptan can be decreased when combined with Propafenone.
Irbesartan Irbesartan Zolmitriptan may decrease the antihypertensive activities of Irbesartan.
Ropinirole Ropinirole Zolmitriptan may increase the sedative activities of Ropinirole.
Finasteride Finasteride The risk or severity of hypertension can be increased when Zolmitriptan is combined with Finasteride.
Quetiapine Quetiapine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Quetiapine.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Cetirizine.
Paroxetine Paroxetine The risk or severity of serotonin syndrome can be increased when Paroxetine is combined with Zolmitriptan.
Tolcapone Tolcapone The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Tolcapone.
Citalopram Citalopram The risk or severity of serotonin syndrome can be increased when Citalopram is combined with Zolmitriptan.
Efavirenz Efavirenz The metabolism of Zolmitriptan can be decreased when combined with Efavirenz.
Celecoxib Celecoxib The risk or severity of hypertension can be increased when Zolmitriptan is combined with Celecoxib.
Rosiglitazone Rosiglitazone The metabolism of Zolmitriptan can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
Thalidomide Thalidomide Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Balsalazide Balsalazide The risk or severity of hypertension can be increased when Zolmitriptan is combined with Balsalazide.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Levetiracetam.
Rabeprazole Rabeprazole The metabolism of Zolmitriptan can be increased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Terbinafine can be decreased when combined with Zolmitriptan.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists