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    HCPCS Details

    HCPC S0013
    Short Description Esketamine, nasal spray
    Long Description Esketamine, nasal spray, 1 mg
    Pricing indicator 00
    Coverage code I
    ASC payment group code
    BETOS2 code Z2
    Action code N
    Type of service 1
    Effective date 2021-01-01
    Date Added 2021-01-01

    Drug Details

    • Esketamine nasal spray is used along with another antidepressant, taken by mouth, to manage treatment-resistant depression (TRD; depression that does not improve with treatment) in adults. It is also used along with another antidepressant, taken by mouth, to treat depressive symptoms in adults with major depressive disorder (MDD) and suicidal thoughts or actions. Esketamine is in a class of medications called NMDA receptor antagonists. It works by changing the activity of certain natural substances in the brain.