NDC 12870-0001-02 — Silver Nitrate Applicators 25 mg/100mg; 75

🆔 Identity & classification

FDA NDC (as labeled) 12870-0001-2

Product NDC 12870-0001

11-digit billing NDC 12870000102

NCPDP billing unit EA — each (per item)

RxCUI 1117536

UNII RU45X2JN0Z, 95IT3W8JZE

SPL Set ID 23b83457-8cbc-26f1-e054-00144ff8d46c

DEA schedule Non-controlled

Marketing category UNAPPROVED DRUG OTHER

Marketing status On market

FDA listing status Listed (active directory)

Marketing start 1937-01-01

Route TOPICAL

Dosage form STICK

Substance POTASSIUM NITRATE; SILVER NITRATE

GPI-14 90509902406340

GPI class Arzol Silver Nit Applicators

GCN Seq No 062055

GCN 97839

HICL code 017855

Ingredient (HICL) Silver Nitrate Applicator

HIC1 code L

Therapeutic class — broad (HIC1) Skin/Subcutaneous Tissue

HIC2 code L5

Therapeutic class — intermediate (HIC2) Keratolytics/Keratoplastics

HIC3 code L5A

Therapeutic class — specific (HIC3) Keratolytics

AHFS code 84:28.00.00

AHFS class Keratolytic Agents

FDB label name SILVER NITRATE APPLICATOR

FDB brand name Silver Nitrate Applicator

Legend status F — Federal legend — prescription drug or device

Why two NDCs? The FDA registers this code as 12870-0001-2 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 12870-0001-02. Same drug, same package — only the format differs.

Where does this data come from?

Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerArzol Chemical Company

Labeler code12870

First marketedJan 1937

Product typeHuman Prescription Drug

🔎 All NDCs from Arzol Chemical Company

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).

Where does this data come from?

Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name SILVER NITRATE APPLICATOR Ingredient Silver Nitrate Applicator

🧪 What is this product?

Silver nitrate applicators are stick-form topical products containing silver nitrate and potassium nitrate. Silver nitrate is typically used as a caustic agent to remove or destroy unwanted tissue growths, such as warts or granulation tissue, and has been used historically in wound care. Potassium nitrate functions as an oxidizing agent and is commonly included in such products to support the chemical action. This product is marketed without an approved FDA application.

Patient education

📘 MedlinePlus patient leaflet ↗

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →

Where does this data come from?

Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

A current SPL was checked, but it does not contain a structured or narrative inactive-ingredient list for this product. This does not mean the product has no inactive ingredients.

Where does this data come from?

Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?

No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.

Why might an inactive ingredient be missing?

Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.

Can inactive ingredients matter?

Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price system	Per each	Per package
Retail pharmacies payNADAC · weekly	Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo	No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly	No Part D plan price is available for this NDC in our data.

ℹ️

No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.

Try another pack size: 10 packets

Where does this data come from?

NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

Product	Labeler	Pack	NADAC/unit	TE	Status	Price vs. this
Styptstix 38.21 mg/1; 12.74 mg 00404-1000-01	Henry	12 tubes	—	—	FDA listed	—
Grafco Applicator 15 Cm 38.21 mg/1; 12.74 mg 12165-0100-01	GF	100 sticks	—	—	FDA listed	—
Grafco Applicator 30 Cm 52.451 mg/1; 17.486 mg 12165-0200-03	GF	100 sticks	—	—	FDA listed	—
Grafco Applicator 45 Cm 73.4314 mg/1; 24.4804 mg 12165-0300-01	GF	1 stick	—	—	FDA listed	—
Silver Nitrate Applicators 25 mg/100mg; 75 mg/100mgthis 12870-0001-02	Arzol	100 applicators	—	—	FDA listed	—
Grafco Silver Nitrate (75% Silver Nitrate, 25% Potassium Nitrate) 12.74 mg/1; 38.21 mg 51662-1611-01	HF	100 sticks	—	—	FDA listed	—
Avoca Flexible Caustic Applicator 30 mg/40mg 65875-0101-09	Bray	10 vials	—	—	FDA listed	—
Swabs 25 g/100mL; 75 g/100mL 68599-6303-08	McKesson	10 swabs	—	—	FDA listed	—

About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.

Where does this data come from?

Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️

1937

On the market since

Jan 1937

📍

2026

Currently FDA-listed

89 years listed

🔒

·

No generic listed yet

brand only

ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?

Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDC	Description	Marketing start	Status
12870-0001-01	10 PACKET in 1 BOX (12870-0001-1) / 10 APPLICATOR in 1 PACKET / 100 mg in 1 APPLICATOR	1937-01-01	Active
12870-0001-02 You're viewing this	100 APPLICATOR in 1 VIAL (12870-0001-2) / 100 mg in 1 APPLICATOR	1937-01-01	Active

Pack size FAQ

What quantity is in NDC 12870-0001-02?

NDC 12870-0001-02 is listed by the FDA — 100 applicator in 1 vial / 100 mg in 1 applicator.

What NDC number is used to bill for this package of Silver Nitrate Applicators 25 mg/100mg; 75 mg/100mg Stick?

Bill NDC 12870-0001-02 — the 11-digit billing format is 12870000102. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Finished prescription product Marketed without an FDA application

Listed without an FDA application

This product's marketing category indicates it is marketed without an approved FDA application (no NDA, ANDA, or BLA on file). Having an NDC does not by itself establish FDA approval — the NDC Directory is a listing system, not an approval decision. Approval-linked data such as Orange Book therapeutic-equivalence ratings therefore does not apply.

What data is (and isn’t) available for this NDC — tap to expand

NDC identity (package / product / labeler codes)	✓ Available
Labeler	✓ Available
Product & package description	✓ Available
Marketing category & status	✓ Available
Active ingredient / dosage form / route	✓ Available
FDA label (SPL via DailyMed)	✓ Available
Package photos	✓ Available
Inactive ingredients (structured)	— Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS)	— Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data	— Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk	— Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD)	— Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.

“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?

An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Unapproved Drug Other". Products approved under an application carry an NDA, ANDA, or BLA number.

Why is there no price listed?

The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.

Is the NDC printed on the package the same as the 11-digit billing NDC?

Yes, they identify this exact package in different formats. The FDA registers it as 12870-0001-2, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 12870-0001-02, written without dashes as 12870000102. The Identity section at the top of this page lists every form of this code.

What do the three segments of this NDC mean?

In 12870-0001-02, the first segment (12870) is the labeler code FDA assigned to Arzol Chemical Company; the middle segment (0001) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (02) identifies this exact package size and type. Together they name one specific package of one specific product.

Is this package still being marketed?

Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Arzol Chemical Company. Listing status can change — the directory data on this page refreshes weekly.

Does this product come in other package sizes?

Yes — the FDA directory lists 1 other package presentation of this same product, including 10 packets (12870-0001-01). Each has its own NDC and its own page — see the package list near the top of this page.

Who lists this product with the FDA?

Arzol Chemical Company is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.

Do I need a prescription for this product?

This NDC is listed with FDA as a prescription product, so it is dispensed under a prescriber's order. Your pharmacist can tell you whether any over-the-counter forms of the same medication exist.

This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.

Where does this data come from?

Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 Full prescribing information FDA SPL

The complete FDA label for this product — the official prescribing information, verbatim, section by section. Jump with a chip, search within the label, or expand everything.

🎯 Indications and Usage ⏱️ Dosage and Administration 💊 Dosage Forms and Strengths ⚠️ Warnings and Cautions ⚠️ Warnings 🤒 Adverse Reactions 📦 How Supplied / Storage and Handling 📦 Storage and Handling 📋 Description

🎯 Indications and Usage 77 words ▾

INDICATIONS On the skin, applications of silver nitrate are recommended for cauterization of wounds and sluggish ulcers, also for removal of granulation tissue and warts. On mucous membranes, silver nitrate may be applied to small ulcers and aphthae in the mouth resulting from injury or stomatitis, to infected tonsils, to rectal fissures and fistulae, and to vaginal or cervical ulcerations or erosions. Epistaxis may be controlled by direct application to the site of hemorrhage within the nostrils.

⏱️ Dosage and Administration 44 words ▾

APPLICATION ARZOL may be applied direct to mucous membranes and other moist surfaces. In the case of dry skin, the applicator tip should be dipped in water immediately before use. Apply carefully to the area to be treated. DO NOT USE ON THE EYES.

💊 Dosage Forms and Strengths 24 words ▾

Silver Nitrate 75% Potassium Nitrate 25%

(Silver Nitrate 75%) (Potassium Nitrate 25%)

Silver Nitrate 75% Potassium Nitrate 25%

⚠️ Warnings and Cautions 59 words ▾

WARNING: Keep out of reach of children. Keep in dry and dark place. Do not use on the eyes.

Warning: Do not use on the eyes. Keep out of reach of children. Keep in a dry and dark place.

⚠️ Warnings 81 words ▾

SIDE EFFECTS Silver nitrate blackens the tissues to which it is applied but this discoloration gradually disappears. In the case of applicators, poisoning from ingestion is rare.

POISON

CAUTION: Federal law prohibits dispensing without prescription. Do not open this box or dispense packets or applicators separately.

POISON

Caution: Federal law prohibits dispensing without prescription. Do not dispense packets or applicators separately.

NOT FOR RESALE

Caution: Federal law prohibits dispensing without prescription. Do not open this tube or dispense applicators separately.

POISON

🤒 Adverse Reactions 19 words ▾

HAZARDS Long continued applications to large areas may produce argyria, a slate-blue discoloration of the skin and mucous membranes.

📦 How Supplied / Storage and Handling 30 words ▾

AVAILABILITY ARZOL Silver Nitrate Applicators are supplied in boxes of 100 containing 10 packets each with 10 applicators; also, in plastic tubes containing 100 applicators.

100 APPLICATORS

TEN (10) applicators

📦 Storage and Handling 136 words ▾

STABILITY PRECAUTIONS Light causes the silver in the tip to oxidize and turn brown in color. This does not affect the therapeutic action of the tip and the oxidized film readily dissolves when dipped in water. Moisture has a deteriorating effect on the tip. It will cause the tip to break or loosen from the applicator; therefore the applicators should be kept in a dry and dark place.

Stability Precautions Light causes the silver in the tip to oxidize and turn brown in color. This does not affect the therapeutic action of the tip and the oxidized film readily dissolves when dipped in water. Moisture has a deteriorating effect on the tip. It will cause the tip to break or loosen from the applicator; therefore the applicators should be kept in a dry and dark place.

📋 Description 96 words ▾

for Simplified Silver Nitrate Therapy ARZOL Silver Nitrate Applicators provide a simple and convenient means of treating small lesions of the skin and mucous membranes. On contact with living tissue, silver nitrate acts as an escharotic. Deep action is avoided by the formation of a dense surface film of coagulated albumin.

Silver nitrate is a powerful chemical germicide. Despite precipitation, it retains substantial germicidal potency even in the presence of large quantities of albuminous material, possibly by gradually redissolving the silver.

FOR SIMPLIFIED SILVER NITRATE THERAPY

for Simplified Silver Nitrate Therapy

For Simplified Silver Nitrate Therapy

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

🔗 Related NDC lookups

🧪 All Silver Nitrate Applicators NDCsSame ingredient 🏭 All Arzol labeler NDCsLabeler code 12870

💊 Related drugs in this class

Other drugs that share this product’s specific therapeutic class — Keratolytics.

Salicylic Acid 00096-0738-04 Benzoyl Peroxide 00187-0194-10 Salicylic Acid/Sulfur 00536-1962-97 Podophyllum Resin 00574-0601-15 Resorcinol/Sulfur 11086-0022-01

Where does this data come from?

Other drugs sharing this product’s First Databank therapeutic class (HIC3). Each links to that NDC’s page in our directory.