![Frankincense and Myrrh Arthritis Pain Relief Aconitum napellus, Bryonia alba, Hypericum perforatum 3 [hp_X]/59mL; 3 [hp_X]/59mL; 3 [hp_X]/59mL Oil — NDC 42346-0725-59 package photo](https://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=d3b4572d-b186-708a-e053-2995a90ace7e&name=AH-725_02_B_Homeopathic_Arthritis_Oil_CMYK_070922-page-001.jpg)
Frankincense and Myrrh Arthritis Pain Relief Aconitum napellus, Bryonia alba, Hypericum perforatum 3 [hp_X]/59mL; 3 [hp_X]/59mL; 3 [hp_X]/59mL Oil
by Wise Consumer Products · 1 BOTTLE, DROPPER in 1 CARTON (42346-725-59) / 59 mL in 1 BOTTLE, DROPPER
NDC 42346-0725-59
🏷️ FDA NDC (as labeled)
42346-725-59
billing pads the product segment with a zero
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
42346-725-59
Product NDC
42346-725
11-digit billing NDC
42346072559
UNII
U0NQ8555JD, T7J046YI2B, XK4IUX8MNB
SPL Set ID
d3b4572d-b186-708a-e053-2995a90ace7e
DEA schedule
Non-controlled
Marketing category
UNAPPROVED HOMEOPATHIC
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2021-12-21
Route
TOPICAL
Dosage form
OIL
Substance
ACONITUM NAPELLUS; BRYONIA ALBA ROOT; HYPERICUM PERFORATUM
Why two NDCs?
The FDA registers this code as 42346-725-59 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 42346-0725-59. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏭 Manufacturer & labeler
LabelerWise Consumer Products
Labeler code42346
First marketedDec 2021
Product typeHuman Otc Drug
Portfolio7 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
🧪 What is this product?
This is a topical homeopathic oil product marketed for arthritis pain relief. It contains three plant-derived ingredients: aconitum napellus, bryonia alba root, and hypericum perforatum, which are used in homeopathic practice as traditional remedies for joint and muscle discomfort. Homeopathic products are based on traditional use rather than clinical evidence and have not been evaluated by the FDA for safety or effectiveness. This product is intended to be applied to the skin.
Patient education
Supplement & herbal interactions
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Aconitum napellus, Bryonia alba, Hypericum perforatum?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
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UNII 39W1PKE3JI
Bergamot oil is a citrus extract from bergamot orange peel. It's used as a flavoring and fragrance agent to improve taste and aroma in medicines.
-
UNII S92U8SQ71V
A natural oil extracted from cinnamon leaves used as a flavoring agent and fragrance in medicines. It provides taste and aroma to make the product more pleasant to take.
-
UNII S546YLW6E6
Eucalyptus globulus leaf is a plant-derived ingredient that may serve as a flavoring agent or aromatic component in medications. It is commonly used to add taste or scent to oral formulations.
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UNII 67ZYA5T02K
Frankincense oil is a natural aromatic extract from tree resin. In medicines, it's used as a fragrance and flavoring agent to improve taste and smell, and may also help preserve the product.
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UNII 5Q1I94P4WG
A fragrant essential oil derived from geranium plants, used as a flavoring and fragrance agent to improve the taste and smell of medicines.
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UNII I9GRO824LL
Lemon oil is a natural fragrant extract from lemon peel. It's used in medicines as a flavoring agent to mask unpleasant tastes and improve how the medicine tastes to patients.
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UNII H74221J5J4
Myrrh oil is a fragrant resin extracted from myrrh tree bark. It is used in medicines as a flavoring agent and to add aroma or taste to the product.
-
UNII Z1CLM48948
Nutmeg oil is a natural aromatic extract from nutmeg seeds. It's used in medicines as a flavoring agent to improve taste and sometimes as a fragrance to mask bitter or unpleasant odors.
-
UNII AV092KU4JH
A natural oil extracted from peppermint plants. It's used as a flavoring agent to mask bitter tastes and add a refreshing mint flavor to medicines, making them easier to take.
-
UNII 8LGU7VM393
Rosemary leaf oil is a natural aromatic oil extracted from rosemary plants. It's used in medicines as a flavoring agent and preservative to help protect the product from spoilage.
-
UNII 3W1JG795YI
Sunflower oil is a natural vegetable oil derived from sunflower seeds. It serves as a solvent, lubricant, and carrier in medicines, helping dissolve active ingredients and improve how the medication flows and absorbs in the body.
-
UNII R0ZB2556P8
Tocopherol is a form of vitamin E derived from plant oils. It acts as an antioxidant in medicines to prevent oils and fats from breaking down and spoiling during storage.
12 inactive ingredients listed in the exact product block matched to this NDC.
The official label also statesBoswellia Carterii (Frankincense) Oil, Cinnamomum Zeylanicum (Cinnamon) Leaf Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Citrus Limon (Lemon) Peel Oil, Commiphora Myrrha (Myrrh) Oil, Eucalyptus Globulus Leaf Oil, Helianthus Annuus (Sunflower) Seed Oil, Myristica Fragrans (Nutmeg) Kernel Oil, Mentha Piperita (Peppermint) Oil, Pelargonium Graveolens (Geranium) Leaf Oil, Rosmarinus Officinalis (Rosemary) Leaf Oil, Tocopherol
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed —
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per each | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Frankincense and Myrrh Neuropathy 3 [hp_X]/59mL; 3 [hp_X]/59mL; 3 [hp_X]/59mL 42346-0301-59 | Wise | 1 bottle | — | — | FDA listed | — |
| Frankincense and Myrrh Arthritis Pain Relief 3 [hp_X]/59mL; 3 [hp_X]/59mL; 3 [hp_X]/59mLthis 42346-0725-59 | Wise | 1 bottle | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2021
On the market since
Dec 2021
📍
2026
Currently FDA-listed
5 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Frankincense and Myrrh Arthritis Pain Relief (this brand).
Top reported reactions
Age at onset
Reporter sex
Male · 38%
Female · 62%
Unknown · 0%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 42346-0725-59 You're viewing this | 1 BOTTLE, DROPPER in 1 CARTON (42346-725-59) / 59 mL in 1 BOTTLE, DROPPER | 2021-12-21 | Active |
🧭 About this NDC listing & data coverage
Over-the-counter (OTC) product
Homeopathic listing
About homeopathic listings
Frankincense and Myrrh Arthritis Pain Relief Aconitum napellus, Bryonia alba, Hypericum perforatum 3 [hp_X]/59mL; 3 [hp_X]/59mL; 3 [hp_X]/59mL OIL is listed under the homeopathic marketing category. An NDC listing in this category does not by itself establish FDA approval, and FDA does not evaluate homeopathic products for effectiveness. This page reports the listing data as published.
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.
Questions about this listing
Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Unapproved Homeopathic". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 42346-725-59, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 42346-0725-59, written without dashes as 42346072559. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 42346-0725-59, the first segment (42346) is the labeler code FDA assigned to Wise Consumer Products; the middle segment (0725) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (59) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Wise Consumer Products. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Wise Consumer Products is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
📦 Storage and Handling
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses For the temporary relief of minor aches and pains
⏱️ Dosage and Administration ▾
Directions Adults and children 12 years of age and older: apply 10-30 drops into palm or hand and massage into affected areas massage oil in hand to coat painful areas can be used up to 4 times daily children under 12 years of age: consult a physician
⚠️ Warnings ▾
Warnings For external use only Do not use on wounds or damaged skin over large areas of the body When using this product avoid contact with the eyes do not bandage tightly Stop use and ask a doctor if condition worsens irritation occurs symptoms persist for more than 7 days or clear up and occur again within a few days If pregnant or breastfeeding, ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
📦 Storage and Handling ▾
Other information store in a cool, dry place tamper resistant: do not use if seal around bottle neck is broken or missing keep carton, it contains important information claims based on traditional homeopathic practice; not accepted medical evidence. Not FDA evaluated.
🧪 Active Ingredient ▾
Active ingredients Aconitum napellus 3X HPUS* Bryonia alba 3X HPUS* Hypericum perforatum 3X HPUS*
🧪 Inactive Ingredients ▾
Inactive ingredients Boswellia Carterii (Frankincense) Oil, Cinnamomum Zeylanicum (Cinnamon) Leaf Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Citrus Limon (Lemon) Peel Oil, Commiphora Myrrha (Myrrh) Oil, Eucalyptus Globulus Leaf Oil, Helianthus Annuus (Sunflower) Seed Oil, Myristica Fragrans (Nutmeg) Kernel Oil, Mentha Piperita (Peppermint) Oil, Pelargonium Graveolens (Geranium) Leaf Oil, Rosmarinus Officinalis (Rosemary) Leaf Oil, Tocopherol
🎯 Purpose ▾
Purpose Aconitum napellus 3X HPUS*.......................Minor Pain Reliever Bryonia alba 3X HPUS*................................Anti-inflammatory Hypericum perforatum 3X HPUS*................Topical Analgesic *The letters "HPUS" indicate that the components in this product are officially monographed in the Homeopathic Pharmacopoeia of the United States.
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.