Can Arginine Supplements Be Taken With Losartan?
In our latest question and answer, the pharmacist discusses the interaction between arginine supplements and losartan.
Question
Can I take total arginine with losartan 100mg?
Answered by Dr. Brian Staiger, PharmD
Medical Content Reviewed By HelloPharmacist
Staff
Last updated Jan 23, 2025
Answer
Hello and thanks for reaching out to us!
Our herbal-drug interaction checker does list an interaction between arginine and losartan, which can be found on our website (L-arginine - Losartan Potassium Interaction Details | HelloPharmacist).
The interaction is as follows:
- L-arginine boosts nitric oxide, which helps widen blood vessels and can lower blood pressure.
- When combined with certain blood pressure medications, the effects of widening blood vessels and lowering blood pressure can be stronger, increasing the risk of blood pressure dropping too low.
When your blood pressure drops too low, you may experience symptoms such as dizziness and drowsiness, and it also increases your risk of falling.
This interaction is simply a precaution to make you aware of the combined effects of losartan and arginine. If your blood pressure already runs low, it may be more of a concern compared to if you have normal blood pressure.
Arginine also tends to have only intermittent effects and doesn't appear to be long-lasting. So if you only take it as a workout supplement, the long-term risk might not be significant.
I highly recommend speaking with your doctor about whether or not combining losartan and arginine is safe for your medical situation.
Final Words
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References
- Blood pressure and metabolic changes during dietary L-arginine supplementation in humans, PubMed
- Dr. Brian Staiger, PharmD
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