Can You Crush Or Split Amoxicillin?
In our latest question and answer, the pharmacist discusses whether or not amoxicillin tablets can safely be crushed.

Question
I was just put on amoxicillin and they are huge tablets! Can I crush them and take them that way?

Answered by Dr. Brian Staiger, PharmD
Medical Content Reviewed By HelloPharmacist
Staff
Last updated Apr 18, 2025
Key points
- Amoxicillin tablets can safely be crushed.
- There are several other dosage forms of amoxicillin available which may represent better options than crushing the tablets. Alternative dosage forms include capsules, suspension and chewable tablets.
- Moxatag is a rarely prescribed extended-release form of amoxicillin. This product should not be crushed.
Answer
Hello and thanks for reaching out!
Yes, you can crush and split amoxicillin tablets, but you likely have better options available to you since amoxicillin comes in a variety of dosage forms that are easier to swallow than the tablets.
For example, amoxicillin is also available in the following dosage forms:
- Capsules
- Suspension
- Chew Tablets
All three of these are easier to swallow than the tablets, and you don't have to go through the activity of crushing the tablets and taking the powder (which can be messy).
Alternatives To amoxicillin Tablets
As mentioned, if you are having trouble swallowing amoxicillin tablets, I would recommend trying the capsules, chewable tablets, or suspension before resorting to crushing the (non-chewable) tablets.
The capsules are easier to swallow than tablets and they can be opened and sprinkled onto food if you want to take the medication that way.
The suspension is in a liquid dosage form, which again, makes it easier to swallow than the tablet or capsule forms of the drug.
There is nothing wrong or dangerous with crushing amoxicillin tablets, but doing so is just a cumbersome activity and can get messy.
Additionally, amoxicillin tablets are not flavored and have a bitter taste to them. The chewable tablets are flavored and taste much better.
It generally makes more sense to use one of the alternative dosage forms that are readily available if swallowing the large tablets is an issue.
One Exception
There is one exception to what I have written above and it is regarding the drug Moxatag.
Moxatag is an extended-release form of amoxicillin that is not widely prescribed.
Nevertheless, since it is an extended-release dosage form, you should not cut, split, crush or otherwise alter the tablet.
Watch Out For Augmentin
Finally, I want to point out that Augmentin, which is a combination of amoxicillin and clavulanic acid, should not be crushed, as it is an extended-release product.
Sometimes generic Augmentin is referred to as 'amoxicillin' so I just wanted to be sure and clarify to not crush it.
Final Words
Thanks again for your question and please reach back out if anything else comes up!
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Dr. Brian Staiger, PharmD
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