Converting Units (IU) Of Vitamin D To Micrograms (mcg)

The pharmacist discusses how to convert between International Units (IU), micrograms, and milligrams of Vitamin D.

Question

I have a bottle of vitamin D that says it is 400 IU per soft gel. How do I know how many micrograms this is?

Asked by Samantha On May 05, 2022

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published May 05, 2022
Last updated Dec 06, 2024

Key points

  • The strength of a vitamin D supplement can be displayed in metric units (e.g. milligrams, micrograms) or as 'international units' (IU).
  • The conversion between a metric unit and International Unit for Vitamin D is straightforward, 1 IU equals 0.025 mcg. Going the other way, 1 mcg equals 40 IU.

Vitamin D, a fat-soluble vitamin naturally produced in the skin in response to sunlight, is also one of the most purchased over the counter (OTC) supplements. In 2017 alone, supplemental Vitamin D accounted for  $937 million in sales!

A common source of confusion is how the strength of Vitamin D is listed on the supplement label. It's not uncommon to see it listed in:

  • Milligrams
  • Micrograms
  • International Units

The International Unit (IU), which refers to the "biological activity" of a drug or substance, is the most common way in which the strength of Vitamin D is listed, or at least it historically has been.

Here is a vitamin D product manufactured by Nature Made that is labeled as 1000 International Units:

Nature Made Vitamin D

International Units are used to standardize different forms of the same substance, making them easier to compare. For example:

  • Vitamin A: One International Unit (IU) equals 0.3 mcg of retinol or 0.6 mcg of beta-carotene.
  • Vitamin E: One International Unit (IU) equals 0.67 mg of d-alpha-tocopherol or 0.9 mg of dl-alpha-tocopherol
  • Vitamin D: One International Unit (IU) equals 0.025 mcg of cholecalciferol (Vitamin D3) or of ergocalciferol (Vitamin D2)

The Move Away From International Units

Starting in 2021, the International Unit will no longer be the only strength listed on vitamin D supplements. In fact, it may not be listed at all.

New dietary supplement labeling requirements from the FDA (Food and Drug Administration) will go into full effect by January 2021. Among other things, they will require the strength of vitamin A, D and E to be listed as a metric measure (e.g., milligrams or micrograms).

Per the Food Labeling: Revision of the Nutrition and Supplement Facts Labels:

"In addition to changing some DVs [Daily Values], the proposed rule would change the units used to declare vitamins A, E, and D from ‘‘international units,’’ or ‘‘I.U.’’ to a metric measure, milligrams or micrograms, and also would include the absolute amounts in milligrams or micrograms of vitamins and minerals, in addition to the % DV, on the label."

Many manufacturers have already started following these new requirements, by listing both the IU strength and the metric strength on their labels. Here is one example:

Now Foods Vitamin D Label

Hopefully, manufacturers will list both the International Units and the metric strength to assist individuals in finding the appropriate product.

However, there certainly may be situations where you need to convert between one or the other.

Fortunately, the conversion is easy.

Vitamin D Units To Microgram And Milligram Conversion

The conversion between Vitamin D units and micrograms (or milligrams) is easy:

From Micrograms to IU:

  • 1 microgram (mcg) equals 40 IU

Similarly, going from IU to mcg:

  • 1 IU equals 0.025 mcg (micrograms)

The most common strengths you will see are:

  • Vitamin D 400 IU = 10 mcg (0.01 milligrams)
  • Vitamin D 1,000 IU = 25 mcg (0.025 milligrams)
  • Vitamin D 2,000 IU= 50 mcg (0.050 milligrams)
  • Vitamin D 5,000 IU = 125 mcg (0.125 milligrams)
  • Vitamin D 10,000 IU = 250 mcg (0.250 milligrams)
  • Vitamin D 50,000 IU = 1,250 mcg (1.25 milligrams)

So, the specific answer to your question, "400 units of Vitamin D is how many micrograms?", the answer is 10 mcg.

Vitamin D Converter Tool

Use the below tools to help with vitamin D conversions!

Vitamin D Units To Micrograms Calculator

Type in the number of units in the 'Units' field to convert the value to Micrograms:

Micrograms: 0

Vitamin D Micrograms to Units Calculator

Type in the number of micrograms in the 'Micrograms' field to convert the value to International Units:

International Units: 0

References

  • Federal Register: / Vol. 81, No. 103 / Friday, May 27, 2016 /, FDA
  • Ergocalciferol Monograph, PubChem

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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