Does Bergamot Interact With Eliquis?
In our latest question and answer, the pharmacist discusses taking bergamot and Eliquis together.
Is there any interaction between bergamot and Eliquis?
Aug 24, 2024- There is no known interaction between bergamot and Eliquis according to current drug-supplement interaction data.
- Current evidence suggests that bergamot does not significantly affect blood coagulation or interact adversely with Eliquis.
- You should still consult with your doctor before adding bergamot to your routine to ensure appropriate monitoring.
Answer
Hello, and thank you for reaching out to us!
According to our drug-supplement interaction checker, there is no known interaction between bergamot and Eliquis (Bergamot - Apixaban Interaction Details | HelloPharmacist).
Bergamot, a type of citrus fruit, contains various bioactive compounds, including citric acid, limonoids, phenols, and flavonoids such as vicenin-2, naringin, neohesperidin, neoeriocitrin, and rutin.
Bergamot is primarily recognized for its potential cardiovascular benefits, particularly in managing high cholesterol. The flavonoids in bergamot, including naringin, neoeriocitrin, and neohesperidin, are structural analogs of statins (drugs like Lipitor and Zocor). They have been shown to reduce cholesterol biosynthesis, increase cholesterol excretion, and enhance vasodilation.
Additionally, these compounds may reduce triglyceride synthesis in the liver.
Regarding Eliquis, although evidence is limited, current data suggest that bergamot does not significantly affect blood coagulation or interact adversely with medications like Eliquis.
However, as always, I recommend consulting with your doctor before adding any new medication or supplement to your current regimen to ensure appropriate monitoring.
Thank you again for contacting us!
References & sources
- The effect of bergamot (KoksalGarry) supplementation on lipid profiles: A systematic review and meta-analysis of randomized controlled trials — PubMed
Glossary — Terms in This Answer
- Eliquis
- A prescription blood-thinning medication used to prevent blood clots and reduce stroke risk in patients with certain heart conditions.
- Bioactive compounds
- Natural substances in foods that can affect how your body functions beyond basic nutrition.
- Flavonoids
- Plant-based compounds with antioxidant properties found in many fruits and vegetables.
- Statins
- A class of prescription drugs used to lower cholesterol levels in the blood.
- Cholesterol biosynthesis
- The body's natural process of creating cholesterol internally.
- Vasodilation
- The widening of blood vessels, which allows blood to flow more easily.
- Triglyceride
- A type of fat found in blood that can increase health risks when levels are too high.
- Blood coagulation
- The body's process of forming blood clots to stop bleeding.
Dr. Brian Staiger, PharmD
Doctor of Pharmacy, board certified clinical pharmacist (BCPS), American Herbalist Guild, Medication Therapy Management certified
Brian Staiger, PharmD, BCPS, is a licensed pharmacist with more than 13 years of experience across retail pharmacy, clinical pharmacy, medication safety, pharmacy program development, and healthcare administration. He is the founder of HelloPharmacist.com, where he helps patients...
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