Is Green Tea Safe With Eliquis?

In our latest question and answer, our pharmacist discusses whether or not green tea interacts with Eliquis.

Question

Can I take green tea diet pills while on Eliquis?

Asked by Jenn On Jan 11, 2023

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Jan 11, 2023
Last updated May 17, 2024

Key points

  • Green tea may have a mild blood-thinning effect and should be used cautiously if you are taking antiplatelet or anticoagulant drugs.
  • Most studies report that the blood-thinning effects of green tea are likely very minor, but it is important to know what to look out for if you take blood-thinning medication (like bleeding gums, easy bruising, and black/tarry stools).

Answer

Thanks for reaching out! You specifically mentioned 'green tea diet pills' in your question but didn't say if you were considering a specific product (which may or may not contain additional ingredients). So, I'll write about whether or not green tea itself, or an extract, is safe with Eliquis.

If you have a specific product in mind you want to ask about, please be sure to reach out to us again.

Green Tea With Eliquis

First and foremost, there are going to be many over-the-counter dietary supplements that have a theoretical interaction with Eliquis (apixaban) simply because Eliquis is an anticoagulant drug and countless herbals and supplements are purported to have at least mild anticoagulant effects.

That is what we see when we look at combining green tea with Eliquis.

Green tea, both as a liquid or when used as an extract in dietary supplements marketed for weight loss, may have mild anticoagulant effects. This, in theory, increases the risk of bleeding.

It has to be said though, that evidence regarding the anticoagulant effects (i.e., blood-thinning effects) of green tea is quite conflicting. Some studies have shown it may have very mild effects on blood clotting caused by a few compounds found in green tea, namely catechins and caffeine, but most studies report that the interaction is likely clinically insignificant when consuming usual amounts of green tea (and not extremely high doses).

It also must be noted that most studies that have evaluated the anticoagulant effects of green tea have only been done in a lab setting (i.e., in vitro) and human evidence is lacking.

So, overall, although there is likely only a very small risk of a clinically significant interaction, it's always important to be on the lookout for signs and symptoms of bleeding, especially when taking a drug like Eliquis. Symptoms to look out for include easy bruising and bleeding, bleeding gums, and black/tarry stools.

Also, be sure to let your doctor know about all the medication you are taking so you can be appropriately monitored.

Be Cautious With Any Blood-Thinning Medication

As mentioned, although green tea is unlikely to have strong anticoagulant/antiplatelet effects, you should be cautious about combining it with certain medications. That, of course, includes the drug in question here, Eliquis, but also other blood-thinning medications, such as:

Always watch for signs of easy bruising or bleeding when taking blood-thinning medication.

Final Words

Thanks again for contacting us! Feel free to contact us again anytime, and be sure to use our free 'drug-herbal interaction checker' as well!

References

  • Antiplatelet effect of green tea catechins: a possible mechanism through arachidonic acid pathway, PubMed
  • Antiplatelet activity of green tea catechins is mediated by inhibition of cytoplasmic calcium increase, PubMed
  • Blood anticoagulation and antiplatelet activity of green tea (-)-epigallocatechin (EGC) in mice, PubMed
  • Antithrombotic activities of green tea catechins and (-)-epigallocatechin gallate, PubMed

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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