Phosphatidylcholine With Plavix Question
In our latest question and answer, the pharmacist discusses the lack of an interaction between Plavix and phosphatidylcholine.
Hi, would taking a PC Phosphatidylcholine supplement interact with clopidogrel?
Mar 16, 2024- There is no known interaction between phosphatidylcholine and Plavix according to current database information.
- Phosphatidylcholine does not appear to affect blood coagulation or platelets.
- It's important to discuss any new supplements with your doctor before starting them alongside your medications.
Answer
Thank you for contacting us!
According to our database, there is no known interaction between phosphatidylcholine and Plavix (clopidogrel).
What Is PC?
Phosphatidylcholine (PC) is a phospholipid that plays a vital role in cell membranes, maintaining their structure and function.
PC is a popular dietary supplement used for various purposes, with its most common use being as a memory supplement. Phosphatidylcholine is the body's primary source of choline, a precursor to acetylcholine, a neurotransmitter crucial for memory and cognitive function.
Some studies suggest that PC supplementation may help improve memory and cognitive function, particularly in conditions like dementia where acetylcholine levels are low. However, the effects of oral PC supplementation on acetylcholine levels are still unclear and may vary depending on the individual's cholinergic activity.
Interactions
Our database lists no interactions between phosphatidylcholine and prescription or over-the-counter medication.
In fact, clinical studies show that phosphatidylcholine (PC) is generally well-tolerated. When taken orally, mild side effects such as bloating, diarrhea, altered taste, nausea, vomiting, sweating, and itching have been reported, especially with larger doses around 30 grams daily. There do not appear to be any issues with phosphatidylcholine affecting blood coagulation or platelets.
Nevertheless, the lack of documented interactions may simply be due to a paucity of research on the subject, so, as always where dietary supplements are concerned, it's important to be cautious when starting new ones.
Final Words
Thank you again for reaching out to us.
Be sure to talk to your doctor before starting any new supplements with your medication so you can be monitored appropriately.
References & sources
Glossary — Terms in This Answer
- Phospholipid
- A type of fat molecule that forms the basic structure of cell membranes.
- Dietary supplement
- A product taken by mouth that contains vitamins, minerals, herbs, or other substances meant to add nutritional value to the diet.
- Choline
- A nutrient that the body uses to make acetylcholine, an important chemical for brain function.
- Acetylcholine
- A chemical messenger in the brain and body that helps with memory, thinking, and muscle control.
- Neurotransmitter
- A chemical that carries signals between nerve cells in the brain and throughout the body.
- Dementia
- A serious condition where a person gradually loses memory and thinking abilities.
- Blood coagulation
- The process by which blood clots to stop bleeding.
- Platelets
- Tiny blood cells that help form clots to stop bleeding.
Dr. Brian Staiger, PharmD
Doctor of Pharmacy, board certified clinical pharmacist (BCPS), American Herbalist Guild, Medication Therapy Management certified
Brian Staiger, PharmD, BCPS, is a licensed pharmacist with more than 13 years of experience across retail pharmacy, clinical pharmacy, medication safety, pharmacy program development, and healthcare administration. He is the founder of HelloPharmacist.com, where he helps patients...
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