Taking Robitussin DM With Allegra

In our latest question and answer, the pharmacist discusses whether or not there is a drug interaction between Robitussin DM and Allegra.

Question

Can I take Robitussin Cough and Chest with Allegra?

Asked by Ann On Oct 06, 2022

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Oct 06, 2022
Last updated Apr 25, 2024

Key points

  • There is no interaction between the drugs contained in Robitussin DM (dextromethorphan; guaifenesin) and Allegra.

Answer

Thanks for reaching out to us! There is no known drug interaction between Robitussin DM (dextromethorphan; guaifenesin) and Allegra (fexofenadine). They are considered safe to take together.

Taking both can help cover more symptoms of a cold/flu (e.g. running nose, cough, chest congestion, watery eyes etc...) than either drug alone.

What Is Robitussin DM?

Robitussin DM contains two drugs:

  • Dextromethorphan
  • Guaifenesin

Dextromethorphan is a cough suppressant used to temporarily relieve cough caused by the common cold, the flu, or other conditions. It will relieve a cough but will not treat the cause of the cough or speed recovery.

Dextromethorphan is in a class of medications called antitussives. It works by decreasing activity in the part of the brain that causes coughing.

Guaifenesin is an expectorant and is used to relieve chest congestion. It is in a class of medications called expectorants and works by thinning the mucus in the air passages to make it easier to cough up the mucus and clear the airways.

What Is Allegra?

Allegra (fexofenadine) is used to relieve the allergy symptoms of seasonal allergic rhinitis (''hay fever''), including runny nose; sneezing; red, itchy, or watery eyes; or itching of the nose, throat, or roof of the mouth in adults and children 2 years of age and older. It is also used to relieve symptoms of urticaria (hives; red, itchy raised areas of the skin), including itching and rash in adults and children 6 months of age and older.

Allegra is in a class of medications called antihistamines and works by blocking the effects of histamine, a substance in the body that causes allergy symptoms.

Combined Use

As mentioned, it is perfectly safe to combine Robitussin DM and Allegra. In fact, Allegra can be combined with most cough/cold medications as long as the other medication doesn't already contain an antihistamine.

Final Words

Thanks again for reaching out to us! I hope you found this helpful.

References

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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