Will Phentermine Show Up On A Drug Test?

In our latest question and answer, the pharmacist discusses whether or not phentermine will show up on a drug test.

Question

I just took a Phentermine at 11:04 am Sunday. I have to take a drug test by 4:30 pm this Tuesday (2 days away). I have a high metabolism and I drink lots of water. Can I pass this test by then? I've only taken one and won't take another

Asked by La La On Sep 02, 2022

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Sep 02, 2022
Last updated May 05, 2024

Key points

  • Phentermine can be tested for on a urine drug screening but is not part of your typical panel.
  • Phentermine can sometimes cause false-positive results for amphetamines.

Answer

Phentermine can be detected on urine drug tests if it is being tested for. However, it is generally not part of your standard 5 or 7-panel drug screen.

However, and this is an important point, phentermine is closely related to amphetamine, and has been reported to cause false-positive tests for both amphetamine and methamphetamine. Therefore, it is important to let your doctor and tester know all the drugs you are taking to avoid any confusion with the results.

How Long Does Phentermine Last In Your System?

Based on the pharmacokinetic profile of phentermine, it can last in your body for nearly 5 days as the half-life of the drug is relatively long, around 19-24 hours.

In terms of drug testing specifically, most institutes allow you to give them a list of prescription medications when a drug screen comes back positive, so when you are able to provide a prescription for phentermine they likely will report back to whoever ordered the drug screen that you are clean.

Phentermine Information

Phentermine is a stimulant that suppresses appetite and is used to treat obesity. This is a controlled substance, so it can only be obtained by a prescription in the United States. This medication is typically dosed 1-2 times a day and this is due to the fact that this medication has a long duration of action in the body (around 8-14 hours) and a single dose can stay in the body for upwards of 100 hours.

Phentermine Drug Testing

On most five-panel drug screening tests, they will test for amphetamines. When a patient does test positive for a substance, most drug screening facilities will allow the patient to provide prescription medication lists as there are a number of prescription medications (phentermine included) that will cause a false positive.

When a prescription for a medication is provided they typically amend the drug test to show that there is, in fact, no positive result when reporting to the party who ordered the test.

Based on the time frame you provided (2 days), it will most likely take longer than that for phentermine to leave your system and you likely will have a positive drug screen for some form of amphetamine (e.g. methamphetamine). It may be a good idea to determine up front how to provide the drug screening institution with a list of your prescription medications so that they are better able to evaluate your drug test.

Final Words

Thanks for your question and feel free to reach back out in the future!

References

  • Phentermine Prescribing Information, PubMed
  • SAMHSA Guidelines for Drugs of Abuse Testing, Thermo-Fisher

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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