1,3-dmba - Bisoprolol Interaction

Herbal: 1,3-dmba

Drug: Bisoprolol
Brand names: Zebeta

Medical Content Editor
Last updated Jul 22, 2023

Interaction Details

Bisoprolol is classified as belonging to the following category: Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, 1,3-DMBA might modestly increase the levels of CYP2D6 substrates.
In vitro research shows that 1,3-DMBA weakly inhibits CYP2D6 enzymes.

Interaction Rating

Minor

Likelihood of Occurrence

Possible

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists

References

  • Liu Y, Santillo MF. Cytochrome P450 2D6 and 3A4 enzyme inhibition by amine stimulants in dietary supplements. Drug Test Anal. 2016;8(3-4):307-10.

1,3-dmba Overview

1,3-DMBA, also known as 1,3-dimethylbutylamine, is a chemical present in certain supplements advertised for enhancing athletic performance and aiding in weight loss. While some products claim to derive 1,3-DMBA from pouchong tea or Coreopsis tinctoria, the levels found in these supplements far exceed natural quantities, suggesting synthetic production. Consequently, the US FDA has classified supplements containing 1,3-DMBA as adulterated, and the World Anti-Doping Agency prohibits their use. When taken orally, 1,3-DMBA is considered potentially unsafe due to its stimulant and vasoconstrictive properties, similar to those of 1,3-DMAA, a synthetic stimulant associated with severe side effects such as lactic acidosis, myocardial infarction, stroke, and even death. As a result, it is strongly recommended to avoid oral consumption of 1,3-DMBA.
See More Information Regarding 1,3-dmba

Bisoprolol Overview

  • Bisoprolol is used alone or in combination with other medications to treat high blood pressure. Bisoprolol is in a class of medications called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve and decrease blood pressure.

  • High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

See More Information Regarding Bisoprolol

1,3-dmba - More Interactions

1,3-dmba interacts with 318 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

Visit Our Drug-Herbal Interaction Checker

Drug-Herbal Interaction Checker

Check your medications for potential interactions with herbal supplements

Popular Interaction Pages

Serrapeptase - Cetirizine, Pseudoephedrine
Parsley - Niacin, Lovastatin
Lavender - Spectinomycin
Banana - Aspirin, Butalbital, Caffeine
Tapioca - Glecaprevir, Pibrentasvir
Larch Turpentine - Emapalumab-lzsg
Coca - Topotecan
Arnica - Ammonium Chloride
Cramp Bark - Neomycin, Polymyxin B, Dexamethasone
Rue - Diptheria, Tetanus, Acellular Pertussis Vaccine
Japanese Persimmon - Luliconazole
Partridgeberry - Panobinostat
Vanadium - Nadolol
Policosanol - Acetaminophen, Chlorpheniramine, Pseudoephedrine
Branched-chain Amino Acids (bcaa) - Chlorothiazide, Reserpine
Sida Cordifolia - Elvitegravir
Rosemary - Antipyrine , Benzocaine
Transcutaneous Electrical Acustimulation - Vancomycin Hydrochloride
Mommy's Bliss Gripe Water - Bismuth Subsalicylate (otc Drug)
Shiatsu - Trazodone Hcl

Return to the main herbal interaction checker page

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Dr. Brian Staiger, PharmD

Ask A Pharmacist About Your Herbal Questions!

Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

Ask A Pharmacist