Abuta - Entresto (Sacubitril, Valsartan) Interaction
Herbal: Abuta
Also Known As: Aaknadi, Bejunco de Cerca, Bhatindupat, Butua, False Pareira, Feuille de Velous, Herbe des Sages-Femmes, Krueo Ma Noy, Krung Kha Mao, Menispermaceae, Midwives' Herb, Padha, Padvali, Padvel, Pareira, Patacon, Patha, Poda, Velvetleaf, Venievel, Vigne Maronne, Vigne Sauvage, Xi S
Drug: Sacubitril, Valsartan
Brand names:
Entresto
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jul 22, 2023
Interaction Details
Sacubitril, Valsartan is classified as belonging to the following category: Diuretic Drugs
Theoretically, taking abuta with diuretic drugs might cause additive effects and increase the risk of adverse effects.
Animal research shows that taking abuta causes diuretic effects, including potassium excretion.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Sayana SB, Khanwelkar CC, Nimmagadda VR, et al. Evaluation of diuretic activity of alcoholic extract of roots of cissampelos pareira in albino rats. J Clin Diagn Res. 2014;8(5):HC01-4.
Abuta Overview
Cissampelos pareira is a plant species belonging to the family Menispermaceae. It is commonly known as the "velvet-leaf" or "false pareira" plant, and is native to the tropical regions of Central and South America. The plant is used in traditional medicine to treat a variety of ailments, including kidney and urinary tract disorders. The root of the plant is the part most often used medicinally, but the bark, seed, and above-ground parts are sometimes used as well.
Sacubitril, Valsartan Overview
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The combination of valsartan and sacubitril is usually used in combination with other medications to lower the risk of death and hospitalization in adults with certain types of heart failure. The combination of valsartan and sacubitril is also used to treat certain types of heart failure in children 1 year of age and older. Valsartan is in a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently. Sacubitril is in a class of medications called neprilysin inhibitors. It works to help control blood volume.
Abuta - More Interactions
Abuta interacts with 75 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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