Arabinoxylan - Sutent (Sunitinib) Interaction
Herbal: Arabinoxylan
Also Known As: Arabinoxilano, Arabinoxylane, Pentosan
Drug: Sunitinib
Brand names:
Sutent
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 13, 2024
Interaction Details
There were no interactions found between Sunitinib and Arabinoxylan. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Arabinoxylan Overview
Arabinoxylan is a type of dietary fiber present in the cell walls of cereal grains such as wheat, corn, rice, rye, oat, and barley. It has a structure comprising a xylose backbone with arabinose side chains and can be extracted from byproducts of wheat-flour processing. In natural medicine, arabinoxylan has been utilized to address conditions like diabetes, impaired glucose tolerance, and metabolic syndrome. However, the evidence supporting its effectiveness in these areas is currently insufficient.
Mechanistically, arabinoxylan functions as a prebiotic, fostering the growth of bifidobacteria in the gut. It may also reduce colonic protein fermentation while boosting the production of short-chain fatty acids. Arabinoxylan in clinical research has demonstrated hypoglycemic effects by lowering postprandial glucose levels and hypolipidemic effects by reducing serum triglycerides.
Sunitinib Overview
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Sunitinib is used to treat gastrointestinal stromal tumors (GIST; a type of tumor that grows in the stomach, intestine (bowel), or esophagus (tube that connects the throat with the stomach) in people with tumors that were not treated successfully with imatinib (Gleevec) or people who cannot take imatinib. Sunitinib is also used to treat advanced renal cell carcinoma (RCC, a type of cancer that begins in the cells of the kidneys). Sunitinib is also used to help prevent the return of RCC in people who have RCC that has not spread and have had a kidney removed. Sunitinib is also used to treat pancreatic neuroendocrine tumors (pNET, a type of tumor that begins in certain cells of the pancreas) in people with tumors that have worsened and cannot be treated with surgery. Sunitinib is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop or slow the spread of cancer cells and may help shrink tumors.
Arabinoxylan - More Interactions
Arabinoxylan interacts with 84 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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