Sunitinib

Sunitinib is used to treat gastrointestinal stromal tumors (GIST; a type of tumor that grows in the stomach, intestine (bowel), or esophagus (tube that connects the throat with the stomach) in people with tumors that were not treated successfully with imatinib (Gleevec) or people who cannot take imatinib. Sunitinib is also used to treat advanced renal cell carcinoma (RCC, a type of cancer that begins in the cells of the kidneys). Sunitinib is also used to help prevent the return of RCC in people who have RCC that has not spread and have had a kidney removed. Sunitinib is also used to treat pancreatic neuroendocrine tumors (pNET, a type of tumor that begins in certain cells of the pancreas) in people with tumors that have worsened and cannot be treated with surgery. Sunitinib is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop or slow the spread of cancer cells and may help shrink tumors.

Sunitinib comes as a capsule to take by mouth with or without food. For the treatment of gastrointestinal stromal tumors (GIST), or for the treatment renal cell carcinoma (RCC), sunitinib is usually taken once a day for 4 weeks (28 days) followed by a 2-week break before beginning the next dosing cycle and repeated every 6 weeks for as long as your doctor recommends. For the prevention of RCC, sunitinib is usually taken once a day for 4 weeks (28 days) followed by a 2-week break before beginning the next dosing cycle and repeating every 6 weeks for 9 cycles. For the treatment of pancreatic neuroendocrine tumors (pNET), sunitinib is usually taken once daily. Take sunitinib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sunitinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the capsules whole; do not split, chew, or crush them. Do not open the capsules.

You may need to take one or more capsules at a time depending on your dose of sunitinib.

Your doctor may decrease your dose or temporarily or permanently stop yourtreatment if you experience certain side effects. This depends on how well the medication works for you and the side effects you experience. Talk to your doctor about how you are feeling during your treatment with sunitinib.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking sunitinib,

• tell your doctor and pharmacist if you are allergic to sunitinib, any ingredients of sunitinib capsules, or any other medications. Ask your pharmacist or check the manufacturer's patient information sheet (Medication Guide) for a list of the ingredients.

• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: certain antibiotics such as clarithromycin (Biaxin, in Prevpac), rifampin (Rifadin, Rimactane, in Rifamate, in Rifater), rifabutin (Mycobutin), rifapentine (Priftin), and telithromycin (Ketek); certain antifungals such as itraconazole (Onmel, Sporanox), ketoconazole, and voriconazole (Vfend); dexamethasone; medications for diabetes; certain medications for human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) including atazanavir (Reyataz, in Evotaz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), and saquinavir (Invirase); nefazodone; certain medications for seizures such as carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenobarbital, and phenytoin (Dilantin, Phenytek). Also tell your doctor if you are taking or have taken alendronate (Binosto, Fosamax), etidronate, ibandronate (Boniva), pamidronate, risedronate (Actonel, Atelvia), or zoledronic acid injection (Reclast, Zometa), Other medications may also interact with sunitinib, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

• tell your doctor and pharmacist what herbal products you are taking, especially St. John's wort. Do not take St. John's wort while taking sunitinib.

• tell your doctor if you have or have ever had a bleeding problem; a blood clot in the lungs; a QT interval prolongation (an irregular heart rhythm that can lead to fainting, loss of consciousness, seizures, or sudden death); a slow, fast, or irregular heartbeat; a heart attack; heart failure; high blood pressure; seizures; low blood sugar or diabetes; low levels of potassium or magnesium in your blood; problems with your mouth, teeth or gums; or kidney, thyroid, or heart disease.

• tell your doctor if you are pregnant, plan to become pregnant, or if you plan to father a child. You or your partner should not become pregnant while you are taking sunitinib. If you are female, you will need to have a pregnancy test before you start treatment, and you should use birth control to prevent pregnancy during your sunitinib treatment and for 4 weeks after your final dose. If you are male, you and your partner should use birth control to prevent pregnancy during your treatment with sunitinib and for 7 weeks after your final dose. Talk to your doctor about birth control methods that you can use during your treatment. Sunitinib may decrease fertility in men and women. However, you should not assume that you or your partner cannot become pregnant. If you or your partner become pregnant while taking sunitinib, call your doctor. Sunitinib may harm the fetus.

• tell your doctor if you are breastfeeding. You should not breastfeed during your treatment with sunitinib and for 4 weeks after your final dose.

• if you are having surgery tell the doctor or dentist that you are taking sunitinib. Your doctor will probably tell you to stop taking sunitinib at least 3 weeks before your scheduled surgery because it can affect wound healing. Your doctor will tell you when to start taking sunitinib again after your surgery.

• you should know that sunitinib may cause your skin to turn yellow and your hair to lighten and lose color. This is probably caused by the yellow color of the medication and is not harmful or painful.

• you should know that sunitinib may cause high blood pressure. Your blood pressure should be checked regularly while you are taking sunitinib.

• you should know that sunitinib may cause osteonecrosis of the jaw (ONJ, a serious condition of the jaw bone), especially if you have dental surgery or treatment while you are taking the medication. A dentist should examine your teeth and perform any needed treatments, including cleaning or fixing ill-fitted dentures, before you start to take sunitinib. Be sure to brush your teeth and clean your mouth properly while you are taking sunitinib. Tell your doctor or dentist if you have or have had mouth, teeth, or jaw pain; mouth sores or swelling; numbness or a feeling of heaviness in the jaw; or any loose teeth. Talk to your doctor before having any dental treatments while you are taking this medication.

Do not eat grapefruit or drink grapefruit juice while taking this medication.

If you miss a dose of sunitinib by less than 12 hours, take the missed dose as soon as you remember it and then take the next dose at the scheduled time. However, if you miss a dose by more than 12 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

• Sunitinib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • weakness

  • nausea

  • vomiting

  • diarrhea

  • constipation

  • heartburn

  • gas

  • hemorrhoids

  • pain, irritation, or burning sensation of the lips, tongue, mouth or throat

  • dry mouth

  • change in the way things taste

  • loss of appetite

  • weight changes

  • hair loss

  • thin, brittle fingernails or hair

  • slow speech

  • pale or dry skin

  • shaking

  • heavy, irregular, or missed menstrual periods

  • depression

  • difficulty falling asleep or staying asleep

  • dryness, thickness, cracking, or blistering of skin on the palms of the hands and the soles of the feet

  • muscle, joint, back, or limb pain

  • frequent nosebleeds

  • bleeding from your gums

  • unusual discomfort in cold temperatures

• Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING or SPECIAL PRECAUTIONS sections, call your doctor immediately:

  • unusual bruising or bleeding

  • bloody or black and tarry stools

  • blood in the urine

  • vomit that is bright red or looks like coffee grounds

  • coughing up blood

  • stomach pain, swelling, or tenderness

  • headache

  • fever

  • swelling, tenderness, warmth, or redness of a leg

  • swelling of the feet or ankles

  • rapid, irregular, or pounding heartbeat

  • dizziness or fainting

  • decreased alertness or concentration

  • confusion

  • depression

  • nervousness

  • seizures

  • vision changes

  • chest pain or pressure

  • extreme tiredness

  • shortness of breath

  • pain with deep breathing

  • unexplained weight gain

  • decreased urination

  • cloudy urine

  • swelling of the eyes, face, lips, tongue, or throat

  • rash

  • hives

  • blistering or peeling skin or inside of mouth

  • difficulty swallowing or breathing

  • hoarseness

• Sunitinib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

• If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain tests such as electrocardiograms (EKG, test that records the electrical activity of the heart), echocardiograms (test that uses sound waves to measure your heart's ability to pump blood), and urine tests before and during your treatment with sunitinib to be sure it is safe for you to take sunitinib, and to check your body's response to the medication.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug	Interaction
Moxifloxacin	Moxifloxacin The therapeutic efficacy of Sunitinib can be increased when used in combination with Moxifloxacin.
Repaglinide	Repaglinide The risk or severity of hypoglycemia can be increased when Repaglinide is combined with Sunitinib.
Insulin Glargine (rDNA origin) Injection	Insulin Glargine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Insulin glargine is combined with Sunitinib.
Leflunomide	Leflunomide The risk or severity of adverse effects can be increased when Sunitinib is combined with Leflunomide.
Delavirdine	Delavirdine The metabolism of Sunitinib can be decreased when combined with Delavirdine.
Nevirapine	Nevirapine The metabolism of Sunitinib can be decreased when combined with Nevirapine.
Atorvastatin	Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Sunitinib.
Dolasetron	Dolasetron The risk or severity of QTc prolongation and torsade de pointes can be increased when Sunitinib is combined with Dolasetron.
Alendronate	Alendronate The risk or severity of jaw osteonecrosis and anti-angiogenesis can be increased when Sunitinib is combined with Alendronic acid.
Aminophylline	Aminophylline The metabolism of Aminophylline can be decreased when combined with Sunitinib.
Anagrelide	Anagrelide The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Anagrelide.
Cilostazol	Cilostazol The metabolism of Cilostazol can be decreased when combined with Sunitinib.
Clopidogrel	Clopidogrel The metabolism of Sunitinib can be decreased when combined with Clopidogrel.
Erythromycin and Sulfisoxazole	Erythromycin and Sulfisoxazole The metabolism of Sunitinib can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives)	Estrogen and Progestin (Oral Contraceptives) Sunitinib may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate	Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Sunitinib.
Methylergonovine	Methylergonovine The metabolism of Sunitinib can be decreased when combined with Methylergometrine.
Miglitol	Miglitol The risk or severity of hypoglycemia can be increased when Miglitol is combined with Sunitinib.
Mycophenolate	Mycophenolate The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Sunitinib.
Olsalazine	Olsalazine Olsalazine may increase the hypoglycemic activities of Sunitinib.
Penbutolol	Penbutolol The therapeutic efficacy of Acebutolol can be increased when used in combination with Sunitinib.
Prednisone	Prednisone The risk or severity of hyperglycemia can be increased when Prednisone is combined with Sunitinib.
Reserpine	Reserpine The metabolism of Sunitinib can be increased when combined with Reserpine.
Sumatriptan	Sumatriptan Sunitinib may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus	Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Sunitinib.
Tiludronate	Tiludronate The risk or severity of jaw osteonecrosis and anti-angiogenesis can be increased when Sunitinib is combined with Etidronic acid.
Tizanidine	Tizanidine The risk or severity of QTc prolongation can be increased when Tizanidine is combined with Sunitinib.
Triamcinolone	Triamcinolone The risk or severity of hyperglycemia can be increased when Triamcinolone is combined with Sunitinib.
Doxycycline Injection	Doxycycline Injection The metabolism of Sunitinib can be decreased when combined with Doxycycline.
Famotidine Injection	Famotidine Injection The risk or severity of QTc prolongation can be increased when Famotidine is combined with Sunitinib.
Fluconazole Injection	Fluconazole Injection The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Fluconazole.
Foscarnet Injection	Foscarnet Injection The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Sunitinib.
Interferon Beta-1b Injection	Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Sunitinib.
Interferon Gamma-1b Injection	Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Sunitinib.
Levofloxacin Injection	Levofloxacin Injection The therapeutic efficacy of Sunitinib can be increased when used in combination with Levofloxacin.
Meperidine Injection	Meperidine Injection The metabolism of Meperidine can be increased when combined with Sunitinib.
Methylprednisolone Injection	Methylprednisolone Injection The risk or severity of hyperglycemia can be increased when Methylprednisolone is combined with Sunitinib.
Metoclopramide Injection	Metoclopramide Injection The risk or severity of QTc prolongation can be increased when Metoclopramide is combined with Sunitinib.
Metronidazole Injection	Metronidazole Injection The metabolism of Sunitinib can be decreased when combined with Metronidazole.
Pamidronate Injection	Pamidronate Injection The risk or severity of jaw osteonecrosis and anti-angiogenesis can be increased when Sunitinib is combined with Pamidronic acid.
Zidovudine Injection	Zidovudine Injection The risk or severity of adverse effects can be increased when Zidovudine is combined with Sunitinib.
Altretamine	Altretamine Amphetamine may increase the hypoglycemic activities of Sunitinib.
Cyclosporine	Cyclosporine Sunitinib may increase the immunosuppressive activities of Cyclosporine.
Ondansetron	Ondansetron The risk or severity of QTc prolongation and torsade de pointes can be increased when Sunitinib is combined with Ondansetron.
Granisetron	Granisetron The risk or severity of QTc prolongation and torsade de pointes can be increased when Sunitinib is combined with Granisetron.
Torsemide	Torsemide The therapeutic efficacy of Sunitinib can be increased when used in combination with Torasemide.
Olanzapine	Olanzapine The therapeutic efficacy of Sunitinib can be decreased when used in combination with Olanzapine.
Alosetron	Alosetron The risk or severity of QTc prolongation and torsade de pointes can be increased when Sunitinib is combined with Alosetron.
Dofetilide	Dofetilide The metabolism of Dofetilide can be decreased when combined with Sunitinib.
Hydroxychloroquine	Hydroxychloroquine The therapeutic efficacy of Hydroxychloroquine can be increased when used in combination with Sunitinib.
Orlistat	Orlistat The metabolism of Sunitinib can be increased when combined with Orlistat.
Oxcarbazepine	Oxcarbazepine The metabolism of Sunitinib can be increased when combined with Oxcarbazepine.
Risedronate	Risedronate The risk or severity of jaw osteonecrosis and anti-angiogenesis can be increased when Sunitinib is combined with Risedronic acid.
Temozolomide	Temozolomide The risk or severity of adverse effects can be increased when Temozolomide is combined with Sunitinib.
Zaleplon	Zaleplon The metabolism of Sunitinib can be decreased when combined with Zaleplon.
Anakinra	Anakinra The metabolism of Sunitinib can be increased when combined with Anakinra.
Desloratadine	Desloratadine The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Desloratadine.
Linezolid	Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Sunitinib.
Trimipramine	Trimipramine Trimipramine may decrease the hypoglycemic activities of Sunitinib.
Etanercept Injection	Etanercept Injection The metabolism of Sunitinib can be increased when combined with Etanercept.
Modafinil	Modafinil The metabolism of Sunitinib can be increased when combined with Modafinil.
Tenofovir	Tenofovir The metabolism of Tenofovir can be decreased when combined with Sunitinib.
Sirolimus	Sirolimus The metabolism of Sirolimus can be decreased when combined with Sunitinib.
Dutasteride	Dutasteride The metabolism of Sunitinib can be decreased when combined with Dutasteride.
Epinephrine Injection	Epinephrine Injection The metabolism of Sunitinib can be decreased when combined with Epinephrine.
Epirubicin	Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with Sunitinib.
Eplerenone	Eplerenone The metabolism of Sunitinib can be decreased when combined with Eplerenone.
Escitalopram	Escitalopram The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Escitalopram.
Zonisamide	Zonisamide The metabolism of Sunitinib can be decreased when combined with Zonisamide.
Adalimumab Injection	Adalimumab Injection The metabolism of Sunitinib can be increased when combined with Adalimumab.
Aripiprazole	Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Sunitinib.
Atomoxetine	Atomoxetine The risk or severity of QTc prolongation can be increased when Atomoxetine is combined with Sunitinib.
Ezetimibe	Ezetimibe Sunitinib may decrease the excretion rate of Ezetimibe which could result in a higher serum level.
Glatiramer Injection	Glatiramer Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Glatiramer.
Teriparatide Injection	Teriparatide Injection The therapeutic efficacy of Teriparatide can be decreased when used in combination with Sunitinib.
Atazanavir	Atazanavir The metabolism of Atazanavir can be decreased when combined with Sunitinib.
Mefloquine	Mefloquine The metabolism of Sunitinib can be decreased when combined with Mefloquine.
Rosuvastatin	Rosuvastatin The metabolism of Sunitinib can be decreased when combined with Rosuvastatin.
Vardenafil	Vardenafil The metabolism of Vardenafil can be decreased when combined with Sunitinib.
Alfuzosin	Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Sunitinib.
Aprepitant	Aprepitant The metabolism of Sunitinib can be decreased when combined with Aprepitant.
Tegaserod	Tegaserod Sunitinib may decrease the excretion rate of Tegaserod which could result in a higher serum level.
Tadalafil	Tadalafil The metabolism of Sunitinib can be decreased when combined with Tadalafil.
Fosamprenavir	Fosamprenavir The therapeutic efficacy of Sunitinib can be decreased when used in combination with Fosamprenavir.
Gemifloxacin	Gemifloxacin The therapeutic efficacy of Sunitinib can be increased when used in combination with Gemifloxacin.
Progesterone	Progesterone The metabolism of Sunitinib can be increased when combined with Progesterone.
Apomorphine Injection	Apomorphine Injection The metabolism of Sunitinib can be decreased when combined with Apomorphine.
Darbepoetin Alfa Injection	Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Sunitinib.
Infliximab Injection	Infliximab Injection The metabolism of Sunitinib can be increased when combined with Infliximab.
Oxandrolone	Oxandrolone Oxandrolone may increase the hypoglycemic activities of Sunitinib.
Protriptyline	Protriptyline Protriptyline may decrease the hypoglycemic activities of Sunitinib.
Rifaximin	Rifaximin The metabolism of Sunitinib can be increased when combined with Rifaximin.
Duloxetine	Duloxetine The metabolism of Duloxetine can be decreased when combined with Sunitinib.
Norethindrone	Norethindrone The metabolism of Sunitinib can be decreased when combined with Norethisterone.
Bosentan	Bosentan The metabolism of Sunitinib can be increased when combined with Bosentan.
Natalizumab Injection	Natalizumab Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Natalizumab.
Erlotinib	Erlotinib The metabolism of Erlotinib can be decreased when combined with Sunitinib.
Eszopiclone	Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Sunitinib.
Insulin Aspart (rDNA Origin) Injection	Insulin Aspart (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Insulin aspart.
Solifenacin	Solifenacin The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Solifenacin.
Voriconazole	Voriconazole The metabolism of Sunitinib can be decreased when combined with Voriconazole.
Zoledronic Acid Injection	Zoledronic Acid Injection The risk or severity of jaw osteonecrosis and anti-angiogenesis can be increased when Sunitinib is combined with Zoledronic acid.
Dextroamphetamine	Dextroamphetamine Amphetamine may increase the hypoglycemic activities of Sunitinib.
Peginterferon Alfa-2a Injection	Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Sunitinib.
Peginterferon Alfa-2b (PEG-Intron)	Peginterferon Alfa-2b (PEG-Intron) The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Sunitinib.
Pramlintide Injection	Pramlintide Injection The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Pramlintide.
Exenatide Injection	Exenatide Injection The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Exenatide.
Ibandronate	Ibandronate The risk or severity of jaw osteonecrosis and anti-angiogenesis can be increased when Sunitinib is combined with Ibandronate.
Isocarboxazid	Isocarboxazid Isocarboxazid may increase the hypoglycemic activities of Sunitinib.
Fentanyl	Fentanyl The metabolism of Fentanyl can be decreased when combined with Sunitinib.
Pregabalin	Pregabalin The risk or severity of QTc prolongation can be increased when Pregabalin is combined with Sunitinib.
Deferasirox	Deferasirox The metabolism of Sunitinib can be increased when combined with Deferasirox.
Tipranavir	Tipranavir The metabolism of Sunitinib can be decreased when combined with Tipranavir.
Felbamate	Felbamate The metabolism of Sunitinib can be increased when combined with Felbamate.
Insulin Detemir (rDNA Origin) Injection	Insulin Detemir (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Insulin detemir.
Ranolazine	Ranolazine The metabolism of Ranolazine can be decreased when combined with Sunitinib.
Abatacept Injection	Abatacept Injection The metabolism of Sunitinib can be increased when combined with Abatacept.
Rasagiline	Rasagiline Rasagiline may increase the hypoglycemic activities of Sunitinib.
Imatinib	Imatinib The metabolism of Sunitinib can be decreased when combined with Imatinib.
Sitagliptin	Sitagliptin The risk or severity of hypoglycemia can be increased when Sitagliptin is combined with Sunitinib.
Bevacizumab Injection	Bevacizumab Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Bevacizumab.
Gefitinib	Gefitinib The metabolism of Gefitinib can be decreased when combined with Sunitinib.
Albuterol	Albuterol The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Sunitinib.
Paliperidone	Paliperidone The metabolism of Paliperidone can be decreased when combined with Sunitinib.
Bortezomib	Bortezomib The metabolism of Sunitinib can be decreased when combined with Bortezomib.
Clofarabine Injection	Clofarabine Injection The risk or severity of adverse effects can be increased when Clofarabine is combined with Sunitinib.
Hepatitis B Vaccine	Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Sunitinib.
Influenza Vaccine, Inactivated or Recombinant	Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Sunitinib.
Influenza Vaccine, Live Intranasal	Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Sunitinib.
Live Shingles (Zoster) Vaccine (ZVL)	Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Sunitinib.
Insulin Glulisine (rDNA origin) Injection	Insulin Glulisine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Insulin glulisine.
Oxaliplatin Injection	Oxaliplatin Injection The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Sunitinib.
Posaconazole	Posaconazole The metabolism of Sunitinib can be decreased when combined with Posaconazole.
Primaquine	Primaquine The metabolism of Primaquine can be decreased when combined with Sunitinib.
Rituximab Injection	Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Sunitinib.
Bismuth Subsalicylate	Bismuth Subsalicylate Bismuth subsalicylate may increase the hypoglycemic activities of Sunitinib.
Darunavir	Darunavir The serum concentration of Sunitinib can be increased when it is combined with Darunavir.
Pemetrexed Injection	Pemetrexed Injection The risk or severity of adverse effects can be increased when Pemetrexed is combined with Sunitinib.
Dimenhydrinate	Dimenhydrinate The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Dimenhydrinate.
Retapamulin	Retapamulin The metabolism of Retapamulin can be decreased when combined with Sunitinib.
Vorinostat	Vorinostat The risk or severity of adverse effects can be increased when Sunitinib is combined with Vorinostat.
Sorafenib	Sorafenib The metabolism of Sunitinib can be decreased when combined with Sorafenib.
Lapatinib	Lapatinib The metabolism of Sunitinib can be decreased when combined with Lapatinib.
Levocetirizine	Levocetirizine The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Levocetirizine.
Dasatinib	Dasatinib The metabolism of Dasatinib can be decreased when combined with Sunitinib.
Armodafinil	Armodafinil The metabolism of Sunitinib can be increased when combined with Armodafinil.
Azacitidine Injection	Azacitidine Injection The risk or severity of adverse effects can be increased when Azacitidine is combined with Sunitinib.
Ivermectin	Ivermectin The metabolism of Ivermectin can be increased when combined with Sunitinib.
Temsirolimus	Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Sunitinib.
Nelarabine Injection	Nelarabine Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Nelarabine.
Lenalidomide	Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with Sunitinib.
Nilotinib	Nilotinib The metabolism of Nilotinib can be decreased when combined with Sunitinib.
Toremifene	Toremifene The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Toremifene.
Bexarotene	Bexarotene The metabolism of Sunitinib can be increased when combined with Bexarotene.
Budesonide	Budesonide The risk or severity of hyperglycemia can be increased when Sunitinib is combined with Budesonide.
Chloramphenicol Injection	Chloramphenicol Injection The metabolism of Sunitinib can be decreased when combined with Chloramphenicol.
Decitabine Injection	Decitabine Injection The risk or severity of adverse effects can be increased when Decitabine is combined with Sunitinib.
Etravirine	Etravirine The metabolism of Sunitinib can be increased when combined with Etravirine.
Arsenic Trioxide Injection	Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Arsenic trioxide is combined with Sunitinib.
Mitoxantrone Injection	Mitoxantrone Injection The metabolism of Sunitinib can be decreased when combined with Mitoxantrone.
Desvenlafaxine	Desvenlafaxine The metabolism of Desvenlafaxine can be decreased when combined with Sunitinib.
Nebivolol	Nebivolol The therapeutic efficacy of Nebivolol can be increased when used in combination with Sunitinib.
Tretinoin	Tretinoin The metabolism of Sunitinib can be decreased when combined with Tretinoin.
Bendamustine Injection	Bendamustine Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Bendamustine.
Pilocarpine	Pilocarpine The metabolism of Sunitinib can be decreased when combined with Pilocarpine.
Flecainide	Flecainide The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Flecainide.
Certolizumab Injection	Certolizumab Injection The metabolism of Sunitinib can be increased when combined with Certolizumab pegol.
Ixabepilone Injection	Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Sunitinib.
Irinotecan Injection	Irinotecan Injection The metabolism of Sunitinib can be decreased when combined with Irinotecan.
Estramustine	Estramustine The risk or severity of adverse effects can be increased when Estramustine is combined with Sunitinib.
Praziquantel	Praziquantel The metabolism of Sunitinib can be decreased when combined with Praziquantel.
Mitotane	Mitotane The metabolism of Sunitinib can be increased when combined with Mitotane.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia)	Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Sunitinib.
Rufinamide	Rufinamide The metabolism of Rufinamide can be increased when combined with Sunitinib.
Midazolam	Midazolam The serum concentration of Midazolam can be increased when it is combined with Sunitinib.
Dexrazoxane Injection	Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Sunitinib.
Ibritumomab Injection	Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Sunitinib.
Milnacipran	Milnacipran The metabolism of Milnacipran can be decreased when combined with Sunitinib.
Degarelix Injection	Degarelix Injection The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Degarelix.
Betaxolol	Betaxolol The therapeutic efficacy of Betaxolol can be increased when used in combination with Sunitinib.
Iloperidone	Iloperidone The metabolism of Iloperidone can be decreased when combined with Sunitinib.
Lacosamide	Lacosamide The metabolism of Lacosamide can be decreased when combined with Sunitinib.
Everolimus	Everolimus The metabolism of Everolimus can be decreased when combined with Sunitinib.
Tolvaptan (low blood sodium)	Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be decreased when combined with Sunitinib.
Dronedarone	Dronedarone The serum concentration of Dronedarone can be increased when it is combined with Sunitinib.
Pralatrexate Injection	Pralatrexate Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Pralatrexate.
Palonosetron Injection	Palonosetron Injection The risk or severity of QTc prolongation and torsade de pointes can be increased when Sunitinib is combined with Palonosetron.
Saxagliptin	Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Sunitinib.
Telavancin Injection	Telavancin Injection The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Telavancin.
Romidepsin Injection	Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Sunitinib.
Topotecan	Topotecan The metabolism of Topotecan can be increased when combined with Sunitinib.
Golimumab Injection	Golimumab Injection The metabolism of Sunitinib can be increased when combined with Golimumab.
Pazopanib	Pazopanib The metabolism of Pazopanib can be decreased when combined with Sunitinib.
Asenapine	Asenapine The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Asenapine.
Pitavastatin	Pitavastatin Sunitinib may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Albendazole	Albendazole The metabolism of Albendazole can be decreased when combined with Sunitinib.
Levonorgestrel	Levonorgestrel The metabolism of Sunitinib can be decreased when combined with Levonorgestrel.
Denosumab Injection	Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Sunitinib.
Liraglutide Injection	Liraglutide Injection The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Liraglutide.
Tocilizumab Injection	Tocilizumab Injection The metabolism of Sunitinib can be increased when combined with Tocilizumab.
Fingolimod	Fingolimod Sunitinib may increase the immunosuppressive activities of Fingolimod.
Eribulin Injection	Eribulin Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Eribulin.
Cabazitaxel Injection	Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Sunitinib.
Lurasidone	Lurasidone The therapeutic efficacy of Sunitinib can be decreased when used in combination with Lurasidone.
Acetaminophen Injection	Acetaminophen Injection The metabolism of Acetaminophen can be increased when combined with Sunitinib.
Denileukin Diftitox Injection	Denileukin Diftitox Injection The metabolism of Sunitinib can be decreased when combined with Aldesleukin.
Sipuleucel-T Injection	Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Sunitinib.
Terbutaline Injection	Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Sunitinib.
Belimumab Injection	Belimumab Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Belimumab.
Busulfan Injection	Busulfan Injection The metabolism of Busulfan can be decreased when combined with Sunitinib.
Roflumilast	Roflumilast Roflumilast may increase the immunosuppressive activities of Sunitinib.
Linagliptin	Linagliptin The metabolism of Linagliptin can be decreased when combined with Sunitinib.
Rilpivirine	Rilpivirine The metabolism of Rilpivirine can be decreased when combined with Sunitinib.
Telaprevir	Telaprevir The metabolism of Glecaprevir can be decreased when combined with Sunitinib.
Potassium Iodide	Potassium Iodide The therapeutic efficacy of Potassium Iodide can be decreased when used in combination with Sunitinib.
Cyclophosphamide Injection	Cyclophosphamide Injection The metabolism of Sunitinib can be increased when combined with Cyclophosphamide.
Triptorelin Injection	Triptorelin Injection The therapeutic efficacy of Sunitinib can be decreased when used in combination with Triptorelin.
Rivaroxaban	Rivaroxaban The metabolism of Rivaroxaban can be decreased when combined with Sunitinib.
Ticagrelor	Ticagrelor The metabolism of Sunitinib can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection	Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be decreased when combined with Sunitinib.
Ruxolitinib	Ruxolitinib The metabolism of Ruxolitinib can be decreased when combined with Sunitinib.
Vandetanib	Vandetanib The metabolism of Vandetanib can be decreased when combined with Sunitinib.
Clobazam	Clobazam The metabolism of Sunitinib can be increased when combined with Clobazam.
Vemurafenib	Vemurafenib The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Vemurafenib.
Belatacept Injection	Belatacept Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Belatacept.
Ivacaftor	Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Sunitinib.
Basiliximab Injection	Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Sunitinib.
Axitinib	Axitinib The metabolism of Axitinib can be decreased when combined with Sunitinib.
Crizotinib	Crizotinib The metabolism of Sunitinib can be decreased when combined with Crizotinib.
Melphalan Injection	Melphalan Injection The risk or severity of adverse effects can be increased when Melphalan is combined with Sunitinib.
Cabergoline	Cabergoline The metabolism of Sunitinib can be decreased when combined with Cabergoline.
Naloxone Injection	Naloxone Injection The metabolism of Sunitinib can be decreased when combined with Naloxone.
Ambrisentan	Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Sunitinib.
Eculizumab Injection	Eculizumab Injection The risk or severity of adverse effects can be increased when Eculizumab is combined with Sunitinib.
Carfilzomib Injection	Carfilzomib Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Carfilzomib.
Enzalutamide	Enzalutamide The metabolism of Enzalutamide can be increased when combined with Sunitinib.
Mirabegron	Mirabegron The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Mirabegron.
Regorafenib	Regorafenib The metabolism of Sunitinib can be decreased when combined with Regorafenib.
Bosutinib	Bosutinib The metabolism of Bosutinib can be decreased when combined with Sunitinib.
Corticotropin, Repository Injection	Corticotropin, Repository Injection The risk or severity of hyperglycemia can be increased when Sunitinib is combined with Corticotropin.
Teriflunomide	Teriflunomide The risk or severity of adverse effects can be increased when Sunitinib is combined with Teriflunomide.
Lorcaserin	Lorcaserin The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Mecasermin.
Bedaquiline	Bedaquiline The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Bedaquiline.
Tofacitinib	Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Sunitinib.
Alogliptin	Alogliptin The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Alogliptin.
Dimethyl Fumarate	Dimethyl Fumarate The risk or severity of adverse effects can be increased when Sunitinib is combined with Dimethyl fumarate.
Ponatinib	Ponatinib The metabolism of Ponatinib can be decreased when combined with Sunitinib.
Pomalidomide	Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Sunitinib.
Ado-trastuzumab Emtansine Injection	Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Sunitinib.
Apixaban	Apixaban The metabolism of Apixaban can be decreased when combined with Sunitinib.
Canagliflozin	Canagliflozin Canagliflozin may increase the hypoglycemic activities of Sunitinib.
Methazolamide	Methazolamide The therapeutic efficacy of Sunitinib can be increased when used in combination with Methazolamide.
Dabrafenib	Dabrafenib The metabolism of Dabrafenib can be increased when combined with Sunitinib.
Trametinib	Trametinib The metabolism of Sunitinib can be increased when combined with Trametinib.
Dolutegravir	Dolutegravir Sunitinib may decrease the excretion rate of Dolutegravir which could result in a higher serum level.
Afatinib	Afatinib Sunitinib may decrease the excretion rate of Afatinib which could result in a higher serum level.
Levomilnacipran	Levomilnacipran The risk or severity of hypoglycemia can be increased when Levomilnacipran is combined with Sunitinib.
Vortioxetine	Vortioxetine The risk or severity of QTc prolongation and torsade de pointes can be increased when Sunitinib is combined with Vortioxetine.
Perampanel	Perampanel The metabolism of Perampanel can be increased when combined with Sunitinib.
Ibrutinib	Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Sunitinib.
Lomitapide	Lomitapide The metabolism of Lomitapide can be decreased when combined with Sunitinib.
Obinutuzumab Injection	Obinutuzumab Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Obinutuzumab.
Simeprevir	Simeprevir The metabolism of Simeprevir can be decreased when combined with Sunitinib.
Sofosbuvir	Sofosbuvir Sunitinib may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin	Dapagliflozin Dapagliflozin may increase the hypoglycemic activities of Sunitinib.
Apremilast	Apremilast The metabolism of Sunitinib can be increased when combined with Apremilast.
Ceritinib	Ceritinib The metabolism of Ceritinib can be decreased when combined with Sunitinib.
Siltuximab Injection	Siltuximab Injection The metabolism of Sunitinib can be increased when combined with Siltuximab.
Albiglutide Injection	Albiglutide Injection The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Albiglutide.
Eslicarbazepine	Eslicarbazepine The metabolism of Sunitinib can be increased when combined with Eslicarbazepine.
Vedolizumab Injection	Vedolizumab Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Vedolizumab.
Belinostat Injection	Belinostat Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Belinostat.
Idelalisib	Idelalisib The metabolism of Idelalisib can be decreased when combined with Sunitinib.
Testosterone Injection	Testosterone Injection The metabolism of Testosterone can be increased when combined with Sunitinib.
Oritavancin Injection	Oritavancin Injection The metabolism of Sunitinib can be increased when combined with Oritavancin.
Empagliflozin	Empagliflozin The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Empagliflozin.
Vorapaxar	Vorapaxar The metabolism of Vorapaxar can be decreased when combined with Sunitinib.
Suvorexant	Suvorexant The metabolism of Suvorexant can be decreased when combined with Sunitinib.
Dulaglutide Injection	Dulaglutide Injection The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Dulaglutide.
Peginterferon Beta-1a Injection	Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Peginterferon beta-1a.
Olaparib	Olaparib The metabolism of Olaparib can be decreased when combined with Sunitinib.
Blinatumomab Injection	Blinatumomab Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Blinatumomab.
Tasimelteon	Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Sunitinib.
Riociguat	Riociguat Sunitinib may decrease the excretion rate of Riociguat which could result in a higher serum level.
Lanreotide Injection	Lanreotide Injection The metabolism of Sunitinib can be decreased when combined with Lanreotide.
Pirfenidone	Pirfenidone The risk or severity of adverse effects can be increased when Sunitinib is combined with Pirfenidone.
Nintedanib	Nintedanib The metabolism of Nintedanib can be decreased when combined with Sunitinib.
Secukinumab Injection	Secukinumab Injection The metabolism of Sunitinib can be increased when combined with Secukinumab.
Risperidone Injection	Risperidone Injection The metabolism of Sunitinib can be decreased when combined with Risperidone.
Palbociclib	Palbociclib The metabolism of Palbociclib can be decreased when combined with Sunitinib.
Insulin Human Inhalation	Insulin Human Inhalation The risk or severity of hypoglycemia can be increased when Insulin human is combined with Sunitinib.
Lenvatinib	Lenvatinib The metabolism of Lenvatinib can be increased when combined with Sunitinib.
Panobinostat	Panobinostat The metabolism of Panobinostat can be decreased when combined with Sunitinib.
Dinutuximab Injection	Dinutuximab Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Dinutuximab.
Haloperidol Injection	Haloperidol Injection The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Haloperidol.
Ivabradine	Ivabradine The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Ivabradine.
Isavuconazonium Injection	Isavuconazonium Injection The metabolism of Sunitinib can be increased when combined with Isavuconazonium.
Sonidegib	Sonidegib The metabolism of Sonidegib can be decreased when combined with Sunitinib.
Prednisolone	Prednisolone The risk or severity of hyperglycemia can be increased when Prednisolone is combined with Sunitinib.
Daclatasvir	Daclatasvir The metabolism of Daclatasvir can be decreased when combined with Sunitinib.
Brexpiprazole	Brexpiprazole The therapeutic efficacy of Sunitinib can be decreased when used in combination with Brexpiprazole.
Ziprasidone Injection	Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Ziprasidone.
Insulin Degludec (rDNA Origin) Injection	Insulin Degludec (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Insulin degludec.
Cobimetinib	Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Sunitinib.
Mepolizumab Injection	Mepolizumab Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Mepolizumab.
Trabectedin Injection	Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Sunitinib.
Osimertinib	Osimertinib The metabolism of Osimertinib can be increased when combined with Sunitinib.
Alectinib	Alectinib The metabolism of Alectinib can be decreased when combined with Sunitinib.
Ixazomib	Ixazomib The metabolism of Ixazomib can be decreased when combined with Sunitinib.
Rifapentine	Rifapentine The metabolism of Sunitinib can be increased when combined with Rifapentine.
Lesinurad	Lesinurad The metabolism of Sunitinib can be increased when combined with Lesinurad.
Amphotericin B Liposomal Injection	Amphotericin B Liposomal Injection The metabolism of Sunitinib can be decreased when combined with Amphotericin B.
Dexamethasone Injection	Dexamethasone Injection The risk or severity of hyperglycemia can be increased when Dexamethasone is combined with Sunitinib.
Ixekizumab Injection	Ixekizumab Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Ixekizumab.
Venetoclax	Venetoclax The metabolism of Venetoclax can be decreased when combined with Sunitinib.
Cobicistat	Cobicistat The metabolism of Sunitinib can be decreased when combined with Cobicistat.
Diphenhydramine Injection	Diphenhydramine Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Sunitinib.
Furosemide Injection	Furosemide Injection The therapeutic efficacy of Sunitinib can be increased when used in combination with Furosemide.
Rucaparib	Rucaparib The metabolism of Rucaparib can be decreased when combined with Sunitinib.
Lixisenatide Injection	Lixisenatide Injection The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Lixisenatide.
Ribociclib	Ribociclib The metabolism of Ribociclib can be decreased when combined with Sunitinib.
Brodalumab Injection	Brodalumab Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Brodalumab.
Parathyroid Hormone Injection	Parathyroid Hormone Injection The therapeutic efficacy of Parathyroid hormone can be decreased when used in combination with Sunitinib.
Brigatinib	Brigatinib The metabolism of Brigatinib can be increased when combined with Sunitinib.
Doxepin (Insomnia)	Doxepin (Insomnia) Doxepin may decrease the hypoglycemic activities of Sunitinib.
Deutetrabenazine	Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Sunitinib.
Valbenazine	Valbenazine The metabolism of Valbenazine can be decreased when combined with Sunitinib.
Deflazacort	Deflazacort The risk or severity of hyperglycemia can be increased when Sunitinib is combined with Deflazacort.
Safinamide	Safinamide The metabolism of Sunitinib can be decreased when combined with Safinamide.
Ocrelizumab Injection	Ocrelizumab Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Ocrelizumab.
Sarilumab Injection	Sarilumab Injection The metabolism of Sarilumab can be increased when combined with Sunitinib.
Midostaurin	Midostaurin The metabolism of Sunitinib can be increased when combined with Midostaurin.
Neratinib	Neratinib The metabolism of Neratinib can be decreased when combined with Sunitinib.
Guselkumab Injection	Guselkumab Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Guselkumab.
Abaloparatide Injection	Abaloparatide Injection The therapeutic efficacy of Abaloparatide can be decreased when used in combination with Sunitinib.
Enasidenib	Enasidenib The metabolism of Enasidenib can be decreased when combined with Sunitinib.
Aprepitant/Fosaprepitant Injection	Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Sunitinib.
Copanlisib Injection	Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Sunitinib.
Delafloxacin	Delafloxacin The therapeutic efficacy of Sunitinib can be increased when used in combination with Delafloxacin.
Abemaciclib	Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Sunitinib.
Acalabrutinib	Acalabrutinib The metabolism of Sunitinib can be decreased when combined with Acalabrutinib.
Gemtuzumab Ozogamicin Injection	Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Sunitinib.
Letermovir	Letermovir The metabolism of Sunitinib can be decreased when combined with Letermovir.
Semaglutide Injection	Semaglutide Injection The risk or severity of hypoglycemia can be increased when Sunitinib is combined with Semaglutide.
Tetrabenazine	Tetrabenazine The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Tetrabenazine.
Ertugliflozin	Ertugliflozin The therapeutic efficacy of Sunitinib can be increased when used in combination with Ertugliflozin.
Buprenorphine Injection	Buprenorphine Injection The metabolism of Sunitinib can be decreased when combined with Buprenorphine.
Apalutamide	Apalutamide The metabolism of Sunitinib can be increased when combined with Apalutamide.
Penicillamine	Penicillamine The risk or severity of adverse effects can be increased when Penicillamine is combined with Sunitinib.
Fostamatinib	Fostamatinib The metabolism of Sunitinib can be decreased when combined with Fostamatinib.
Baricitinib	Baricitinib The metabolism of Baricitinib can be decreased when combined with Sunitinib.
Lofexidine	Lofexidine The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Lofexidine.
Eliglustat	Eliglustat The metabolism of Eliglustat can be decreased when combined with Sunitinib.
Encorafenib	Encorafenib The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Encorafenib.
Ivosidenib	Ivosidenib The metabolism of Ivosidenib can be increased when combined with Sunitinib.
Lusutrombopag	Lusutrombopag Sunitinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level.
Doravirine	Doravirine The metabolism of Doravirine can be decreased when combined with Sunitinib.
Cannabidiol	Cannabidiol The metabolism of Sunitinib can be decreased when combined with Cannabidiol.
Dacomitinib	Dacomitinib The metabolism of Dacomitinib can be decreased when combined with Sunitinib.
Duvelisib	Duvelisib The metabolism of Duvelisib can be decreased when combined with Sunitinib.
Stiripentol	Stiripentol The metabolism of Sunitinib can be decreased when combined with Stiripentol.
Talazoparib	Talazoparib Sunitinib may decrease the excretion rate of Talazoparib which could result in a higher serum level.
Gilteritinib	Gilteritinib The metabolism of Gilteritinib can be decreased when combined with Sunitinib.
Glasdegib	Glasdegib The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Glasdegib.
Lorlatinib	Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Sunitinib.
Methoxy Polyethylene Glycol-Epoetin Beta Injection	Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Sunitinib.
Paclitaxel (with albumin) Injection	Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Sunitinib.
Rifamycin	Rifamycin The metabolism of Sunitinib can be increased when combined with Rifamycin.
Prucalopride	Prucalopride The metabolism of Prucalopride can be decreased when combined with Sunitinib.
Ravulizumab-cwvz Injection	Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Ravulizumab.
Emapalumab-lzsg Injection	Emapalumab-lzsg Injection The metabolism of Sunitinib can be increased when combined with Emapalumab.
Siponimod	Siponimod The metabolism of Siponimod can be decreased when combined with Sunitinib.
Erdafitinib	Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Sunitinib.
Risankizumab-rzaa Injection	Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Sunitinib is combined with Risankizumab.
Alpelisib	Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Sunitinib.
Cladribine	Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Sunitinib.
Darolutamide	Darolutamide Sunitinib may decrease the excretion rate of Darolutamide which could result in a higher serum level.
Triclabendazole	Triclabendazole The metabolism of Triclabendazole can be decreased when combined with Sunitinib.
Entrectinib	Entrectinib The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Entrectinib.
Pexidartinib	Pexidartinib Sunitinib may increase the hepatotoxic activities of Pexidartinib.
Istradefylline	Istradefylline The metabolism of Istradefylline can be decreased when combined with Sunitinib.
Pitolisant	Pitolisant The serum concentration of Sunitinib can be decreased when it is combined with Pitolisant.
Lefamulin	Lefamulin Sunitinib may increase the QTc-prolonging activities of Lefamulin.
Phenytoin Injection	Phenytoin Injection The metabolism of Sunitinib can be increased when combined with Phenytoin.
Fosphenytoin Injection	Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Sunitinib.
Zanubrutinib	Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Sunitinib.
Voxelotor	Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Sunitinib.
Ubrogepant	Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Sunitinib.
Tazemetostat	Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Sunitinib.
Cenobamate	Cenobamate The serum concentration of Sunitinib can be decreased when it is combined with Cenobamate.
Teprotumumab-trbw Injection	Teprotumumab-trbw Injection The therapeutic efficacy of Sunitinib can be decreased when used in combination with Teprotumumab.
Ozanimod	Ozanimod Sunitinib may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Selumetinib	Selumetinib The metabolism of Selumetinib can be decreased when combined with Sunitinib.
Rimegepant	Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Sunitinib.
Tucatinib	Tucatinib The metabolism of Tucatinib can be decreased when combined with Sunitinib.
Ripretinib	Ripretinib Sunitinib may decrease the excretion rate of Ripretinib which could result in a higher serum level.
Lemborexant	Lemborexant The metabolism of Lemborexant can be decreased when combined with Sunitinib.
Fostemsavir	Fostemsavir Sunitinib may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Octreotide	Octreotide The therapeutic efficacy of Sunitinib can be decreased when used in combination with Octreotide.
Pralsetinib	Pralsetinib The metabolism of Pralsetinib can be increased when combined with Sunitinib.
Satralizumab-mwge Injection	Satralizumab-mwge Injection The serum concentration of Sunitinib can be decreased when it is combined with Satralizumab.
Relugolix	Relugolix The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Relugolix.
Progestin-Only (drospirenone) Oral Contraceptives	Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Sunitinib can be decreased when combined with Drospirenone.
Vitamin E (Alpha-Tocopherol)	Vitamin E (Alpha-Tocopherol) The metabolism of Sunitinib can be increased when combined with Vitamin E.
Theophylline	Theophylline The metabolism of Theophylline can be decreased when combined with Sunitinib.
Indomethacin	Indomethacin The risk or severity of adverse effects can be increased when Indomethacin is combined with Sunitinib.
Trazodone	Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Sunitinib.
Hydroxyurea	Hydroxyurea The risk or severity of adverse effects can be increased when Hydroxyurea is combined with Sunitinib.
Floxuridine	Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Sunitinib.
Phenobarbital	Phenobarbital The metabolism of Sunitinib can be increased when combined with Phenobarbital.
Methotrexate Injection	Methotrexate Injection The metabolism of Sunitinib can be decreased when combined with Methotrexate.
Primidone	Primidone The metabolism of Sunitinib can be increased when combined with Primidone.
Methsuximide	Methsuximide The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Methsuximide.
Chlorpromazine	Chlorpromazine The metabolism of Chlorpromazine can be increased when combined with Sunitinib.
Diazepam	Diazepam The metabolism of Sunitinib can be decreased when combined with Diazepam.
Lorazepam	Lorazepam The metabolism of Lorazepam can be decreased when combined with Sunitinib.
Carmustine	Carmustine The risk or severity of adverse effects can be increased when Carmustine is combined with Sunitinib.
Amantadine	Amantadine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Sunitinib.
Bromocriptine	Bromocriptine The metabolism of Bromocriptine can be decreased when combined with Sunitinib.
Tranylcypromine	Tranylcypromine The metabolism of Sunitinib can be decreased when combined with Tranylcypromine.
Phenelzine	Phenelzine The metabolism of Sunitinib can be decreased when combined with Phenelzine.
Procarbazine	Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Sunitinib.
Tetracycline	Tetracycline The metabolism of Sunitinib can be decreased when combined with Tetracycline.
Thioguanine	Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Sunitinib.
Prochlorperazine	Prochlorperazine The metabolism of Prochlorperazine can be decreased when combined with Sunitinib.
Thioridazine	Thioridazine The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Thioridazine.
Bleomycin	Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Sunitinib.
Dapsone	Dapsone The metabolism of Sunitinib can be decreased when combined with Dapsone.
Sulfadiazine	Sulfadiazine The therapeutic efficacy of Sunitinib can be increased when used in combination with Sulfadiazine.
Oxycodone	Oxycodone The metabolism of Sunitinib can be decreased when combined with Oxycodone.
Methadone	Methadone The metabolism of Sunitinib can be increased when combined with Methadone.
Oxybutynin	Oxybutynin The metabolism of Sunitinib can be decreased when combined with Oxybutynin.
Benztropine	Benztropine The risk or severity of QTc prolongation can be increased when Benzatropine is combined with Sunitinib.
Maprotiline	Maprotiline The risk or severity of QTc prolongation can be increased when Maprotiline is combined with Sunitinib.
Orphenadrine	Orphenadrine The metabolism of Sunitinib can be decreased when combined with Orphenadrine.
Azathioprine	Azathioprine The risk or severity of adverse effects can be increased when Azathioprine is combined with Sunitinib.
Phentermine	Phentermine The therapeutic efficacy of Sunitinib can be increased when used in combination with Phentermine.
Amoxapine	Amoxapine Amoxapine may decrease the hypoglycemic activities of Sunitinib.
Sulfasalazine	Sulfasalazine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Sunitinib.
Hydrocortisone	Hydrocortisone The risk or severity of hyperglycemia can be increased when Sunitinib is combined with Hydrocortisone.
Lomustine	Lomustine The risk or severity of adverse effects can be increased when Lomustine is combined with Sunitinib.
Doxorubicin	Doxorubicin The metabolism of Doxorubicin can be decreased when combined with Sunitinib.
Cytarabine	Cytarabine The risk or severity of adverse effects can be increased when Cytarabine is combined with Sunitinib.
Mechlorethamine	Mechlorethamine The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Sunitinib.
Dactinomycin	Dactinomycin The risk or severity of adverse effects can be increased when Dactinomycin is combined with Sunitinib.
Carbamazepine	Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Sunitinib.
Clonidine	Clonidine The metabolism of Sunitinib can be decreased when combined with Clonidine.
Prazosin	Prazosin Sunitinib may decrease the excretion rate of Prazosin which could result in a higher serum level.
Hydralazine	Hydralazine The metabolism of Sunitinib can be decreased when combined with Hydralazine.
Cimetidine	Cimetidine The metabolism of Sunitinib can be decreased when combined with Cimetidine.
Warfarin	Warfarin The serum concentration of Warfarin can be increased when it is combined with Sunitinib.
Loperamide	Loperamide The metabolism of Sunitinib can be decreased when combined with Loperamide.
Promethazine	Promethazine The risk or severity of QTc prolongation can be increased when Promethazine is combined with Sunitinib.
Daunorubicin	Daunorubicin The metabolism of Sunitinib can be decreased when combined with Daunorubicin.
Nitrofurantoin	Nitrofurantoin Sunitinib may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Griseofulvin	Griseofulvin The metabolism of Sunitinib can be increased when combined with Griseofulvin.
Digoxin	Digoxin The risk or severity of QTc prolongation can be increased when Digoxin is combined with Sunitinib.
Chloroquine	Chloroquine The metabolism of Sunitinib can be decreased when combined with Chloroquine.
Quinine	Quinine The metabolism of Quinine can be increased when combined with Sunitinib.
Ethosuximide	Ethosuximide The risk or severity of QTc prolongation can be increased when Ethosuximide is combined with Sunitinib.
Calcitriol	Calcitriol The metabolism of Sunitinib can be increased when combined with Calcitriol.
Sulfinpyrazone	Sulfinpyrazone The metabolism of Sunitinib can be increased when combined with Sulfinpyrazone.
Chlorothiazide	Chlorothiazide The therapeutic efficacy of Sunitinib can be decreased when used in combination with Chlorothiazide.
Chlorthalidone	Chlorthalidone The therapeutic efficacy of Sunitinib can be decreased when used in combination with Chlorthalidone.
Metolazone	Metolazone The therapeutic efficacy of Sunitinib can be decreased when used in combination with Metolazone.
Clindamycin Injection	Clindamycin Injection The metabolism of Sunitinib can be decreased when combined with Clindamycin.
Secobarbital	Secobarbital The metabolism of Sunitinib can be increased when combined with Secobarbital.
Desipramine	Desipramine The metabolism of Sunitinib can be decreased when combined with Desipramine.
Amitriptyline	Amitriptyline The metabolism of Sunitinib can be decreased when combined with Amitriptyline.
Imipramine	Imipramine The metabolism of Sunitinib can be decreased when combined with Imipramine.
Probenecid	Probenecid The metabolism of Sunitinib can be increased when combined with Probenecid.
Quinidine	Quinidine The metabolism of Quinidine can be decreased when combined with Sunitinib.
Procainamide	Procainamide The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Procainamide.
Isoniazid	Isoniazid The metabolism of Sunitinib can be decreased when combined with Isoniazid.
Rifampin	Rifampin The metabolism of Sunitinib can be increased when combined with Rifampicin.
Disopyramide	Disopyramide The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Disopyramide.
Valproic Acid	Valproic Acid The metabolism of Valproic acid can be decreased when combined with Sunitinib.
Tamoxifen	Tamoxifen The metabolism of Tamoxifen can be increased when combined with Sunitinib.
Mitomycin	Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with Sunitinib.
Levothyroxine	Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Sunitinib.
Liothyronine	Liothyronine The therapeutic efficacy of Sunitinib can be decreased when used in combination with Liothyronine.
Methimazole	Methimazole The therapeutic efficacy of Sunitinib can be decreased when used in combination with Methimazole.
Propylthiouracil	Propylthiouracil The therapeutic efficacy of Sunitinib can be decreased when used in combination with Propylthiouracil.
Chlorpropamide	Chlorpropamide The risk or severity of hypoglycemia can be increased when Chlorpropamide is combined with Sunitinib.
Tolbutamide	Tolbutamide The risk or severity of hypoglycemia can be increased when Tolbutamide is combined with Sunitinib.
Tolazamide	Tolazamide The risk or severity of hypoglycemia can be increased when Tolazamide is combined with Sunitinib.
Dextromethorphan	Dextromethorphan The metabolism of Sunitinib can be decreased when combined with Dextromethorphan.
Niacin	Niacin The metabolism of Sunitinib can be decreased when combined with Niacin.
Baclofen	Baclofen The therapeutic efficacy of Sunitinib can be decreased when used in combination with Baclofen.
Doxylamine	Doxylamine The risk or severity of QTc prolongation can be increased when Doxylamine is combined with Sunitinib.
Cyproheptadine	Cyproheptadine The risk or severity of QTc prolongation can be increased when Cyproheptadine is combined with Sunitinib.
Clemastine	Clemastine The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Clemastine.
Chlorpheniramine	Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Sunitinib.
Brompheniramine	Brompheniramine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Sunitinib.
Methyclothiazide	Methyclothiazide The therapeutic efficacy of Sunitinib can be decreased when used in combination with Methyclothiazide.
Hydrochlorothiazide	Hydrochlorothiazide The therapeutic efficacy of Sunitinib can be decreased when used in combination with Hydrochlorothiazide.
Folic Acid	Folic Acid Sunitinib may decrease the excretion rate of Folic acid which could result in a higher serum level.
Danazol	Danazol The metabolism of Sunitinib can be decreased when combined with Danazol.
Disulfiram	Disulfiram The metabolism of Sunitinib can be decreased when combined with Disulfiram.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The therapeutic efficacy of Sunitinib can be increased when used in combination with Propranolol.
Pseudoephedrine	Pseudoephedrine The therapeutic efficacy of Sunitinib can be decreased when used in combination with Pseudoephedrine.
Nortriptyline	Nortriptyline The metabolism of Sunitinib can be decreased when combined with Nortriptyline.
Amphotericin B Injection	Amphotericin B Injection The metabolism of Sunitinib can be decreased when combined with Amphotericin B.
Mercaptopurine	Mercaptopurine The risk or severity of adverse effects can be increased when Mercaptopurine is combined with Sunitinib.
Nadolol	Nadolol The therapeutic efficacy of Nadolol can be increased when used in combination with Sunitinib.
Allopurinol	Allopurinol Sunitinib may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Oxytocin Injection	Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Sunitinib.
Fluoxymesterone	Fluoxymesterone Fluoxymesterone may increase the hypoglycemic activities of Sunitinib.
Papaverine	Papaverine The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Papaverine.
Fluorouracil Injection	Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Fluorouracil is combined with Sunitinib.
Colchicine	Colchicine The metabolism of Colchicine can be decreased when combined with Sunitinib.
Cephalexin	Cephalexin The metabolism of Cephalexin can be decreased when combined with Sunitinib.
Dacarbazine	Dacarbazine The risk or severity of adverse effects can be increased when Dacarbazine is combined with Sunitinib.
Acetazolamide	Acetazolamide The metabolism of Sunitinib can be decreased when combined with Acetazolamide.
Calcitonin Salmon Injection	Calcitonin Salmon Injection The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Sunitinib.
Bacillus Calmette-Guerin (BCG) Vaccine	Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Sunitinib.
Ketoconazole	Ketoconazole The metabolism of Sunitinib can be decreased when combined with Ketoconazole.
Thiotepa Injection	Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Sunitinib.
Vincristine Injection	Vincristine Injection The metabolism of Vincristine can be decreased when combined with Sunitinib.
Vinblastine	Vinblastine The metabolism of Sunitinib can be decreased when combined with Vinblastine.
Ethacrynic Acid	Ethacrynic Acid The therapeutic efficacy of Sunitinib can be decreased when used in combination with Etacrynic acid.
Metoprolol	Metoprolol The therapeutic efficacy of Metoprolol can be increased when used in combination with Sunitinib.
Hydroxyzine	Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Sunitinib.
Thiothixene	Thiothixene The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Thiothixene.
Aspirin	Aspirin The risk or severity of hypoglycemia can be increased when Acetylsalicylic acid is combined with Sunitinib.
Chlorambucil	Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Sunitinib.
Alprazolam	Alprazolam The metabolism of Alprazolam can be decreased when combined with Sunitinib.
Triazolam	Triazolam The metabolism of Sunitinib can be decreased when combined with Triazolam.
Hyoscyamine	Hyoscyamine The risk or severity of QTc prolongation can be increased when Hyoscyamine is combined with Sunitinib.
Diltiazem	Diltiazem The metabolism of Sunitinib can be decreased when combined with Diltiazem.
Nifedipine	Nifedipine The metabolism of Sunitinib can be increased when combined with Nifedipine.
Timolol	Timolol The therapeutic efficacy of Timolol can be increased when used in combination with Sunitinib.
Verapamil	Verapamil The metabolism of Sunitinib can be decreased when combined with Verapamil.
Atenolol	Atenolol The therapeutic efficacy of Sunitinib can be increased when used in combination with Atenolol.
Pindolol	Pindolol The therapeutic efficacy of Sunitinib can be increased when used in combination with Pindolol.
Cisplatin Injection	Cisplatin Injection The risk or severity of adverse effects can be increased when Cisplatin is combined with Sunitinib.
Diflunisal	Diflunisal Diflunisal may increase the hypoglycemic activities of Sunitinib.
Bumetanide	Bumetanide The therapeutic efficacy of Sunitinib can be increased when used in combination with Bumetanide.
Streptozocin	Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with Sunitinib.
Etoposide	Etoposide The metabolism of Sunitinib can be increased when combined with Etoposide.
Glyburide	Glyburide The metabolism of Glyburide can be decreased when combined with Sunitinib.
Glipizide	Glipizide The risk or severity of hypoglycemia can be increased when Glipizide is combined with Sunitinib.
Indapamide	Indapamide The therapeutic efficacy of Sunitinib can be decreased when used in combination with Indapamide.
Dicloxacillin	Dicloxacillin The metabolism of Sunitinib can be increased when combined with Dicloxacillin.
Nafcillin Injection	Nafcillin Injection The metabolism of Sunitinib can be increased when combined with Nafcillin.
Pentamidine Injection	Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Sunitinib.
Labetalol	Labetalol The therapeutic efficacy of Sunitinib can be increased when used in combination with Labetalol.
Leuprolide Injection	Leuprolide Injection The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Leuprolide.
Pimozide	Pimozide The metabolism of Pimozide can be decreased when combined with Sunitinib.
Amiodarone	Amiodarone The metabolism of Amiodarone can be decreased when combined with Sunitinib.
Buspirone	Buspirone The metabolism of Sunitinib can be decreased when combined with Buspirone.
Lovastatin	Lovastatin The metabolism of Lovastatin can be decreased when combined with Sunitinib.
Ciprofloxacin	Ciprofloxacin The metabolism of Sunitinib can be decreased when combined with Ciprofloxacin.
Mesalamine	Mesalamine Mesalazine may increase the hypoglycemic activities of Sunitinib.
Fluoxetine	Fluoxetine The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Sunitinib.
Nimodipine	Nimodipine The risk or severity of QTc prolongation can be increased when Nimodipine is combined with Sunitinib.
Interferon Alfa-2b Injection	Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Sunitinib.
Clozapine	Clozapine The metabolism of Sunitinib can be increased when combined with Clozapine.
Idarubicin	Idarubicin The risk or severity of adverse effects can be increased when Idarubicin is combined with Sunitinib.
Ofloxacin	Ofloxacin The therapeutic efficacy of Sunitinib can be increased when used in combination with Ofloxacin.
Fludarabine Injection	Fludarabine Injection The risk or severity of adverse effects can be increased when Fludarabine is combined with Sunitinib.
Pentostatin Injection	Pentostatin Injection The risk or severity of adverse effects can be increased when Pentostatin is combined with Sunitinib.
Clarithromycin	Clarithromycin The metabolism of Sunitinib can be decreased when combined with Clarithromycin.
Benazepril	Benazepril The risk or severity of hypoglycemia can be increased when Benazepril is combined with Sunitinib.
Felodipine	Felodipine The metabolism of Sunitinib can be decreased when combined with Felodipine.
Pravastatin	Pravastatin Sunitinib may decrease the excretion rate of Pravastatin which could result in a higher serum level.
Simvastatin	Simvastatin The metabolism of Sunitinib can be decreased when combined with Simvastatin.
Epoetin Alfa, Injection	Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Sunitinib.
Amlodipine	Amlodipine The risk or severity of hypoglycemia can be increased when Amlodipine is combined with Sunitinib.
Teniposide Injection	Teniposide Injection The metabolism of Sunitinib can be decreased when combined with Teniposide.
Itraconazole	Itraconazole The metabolism of Sunitinib can be decreased when combined with Itraconazole.
Rifabutin	Rifabutin The metabolism of Sunitinib can be increased when combined with Rifabutin.
Sotalol	Sotalol The risk or severity of hypoglycemia can be increased when Sotalol is combined with Sunitinib.
Bisoprolol	Bisoprolol The therapeutic efficacy of Sunitinib can be increased when used in combination with Bisoprolol.
Doxazosin	Doxazosin The metabolism of Doxazosin can be decreased when combined with Sunitinib.
Isradipine	Isradipine The metabolism of Sunitinib can be decreased when combined with Isradipine.
Omeprazole	Omeprazole The metabolism of Sunitinib can be increased when combined with Omeprazole.
Cisapride	Cisapride The metabolism of Sunitinib can be decreased when combined with Cisapride.
Fluvastatin	Fluvastatin The metabolism of Sunitinib can be decreased when combined with Fluvastatin.
Venlafaxine	Venlafaxine The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Sunitinib.
Famciclovir	Famciclovir The metabolism of Famciclovir can be decreased when combined with Sunitinib.
Fluvoxamine	Fluvoxamine The metabolism of Sunitinib can be decreased when combined with Fluvoxamine.
Nefazodone	Nefazodone The metabolism of Sunitinib can be decreased when combined with Nefazodone.
Lamotrigine	Lamotrigine The risk or severity of QTc prolongation can be increased when Lamotrigine is combined with Sunitinib.
Losartan	Losartan The metabolism of Sunitinib can be decreased when combined with Losartan.
Tramadol	Tramadol The metabolism of Tramadol can be decreased when combined with Sunitinib.
Vinorelbine Injection	Vinorelbine Injection The metabolism of Sunitinib can be decreased when combined with Vinorelbine.
Carboplatin Injection	Carboplatin Injection The risk or severity of adverse effects can be increased when Carboplatin is combined with Sunitinib.
Moexipril	Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Sunitinib.
Lansoprazole	Lansoprazole The metabolism of Sunitinib can be increased when combined with Lansoprazole.
Ifosfamide Injection	Ifosfamide Injection The metabolism of Sunitinib can be increased when combined with Ifosfamide.
Pegaspargase Injection	Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Sunitinib.
Nicardipine	Nicardipine The metabolism of Sunitinib can be decreased when combined with Nicardipine.
Ticlopidine	Ticlopidine The metabolism of Ticlopidine can be decreased when combined with Sunitinib.
Saquinavir	Saquinavir The metabolism of Sunitinib can be decreased when combined with Saquinavir.
Metformin	Metformin The risk or severity of hypoglycemia can be increased when Metformin is combined with Sunitinib.
Nisoldipine	Nisoldipine The metabolism of Sunitinib can be decreased when combined with Nisoldipine.
Lamivudine	Lamivudine Sunitinib may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole	Riluzole Sunitinib may decrease the excretion rate of Riluzole which could result in a higher serum level.
Acarbose	Acarbose The risk or severity of hypoglycemia can be increased when Acarbose is combined with Sunitinib.
Glimepiride	Glimepiride The risk or severity of hypoglycemia can be increased when Glimepiride is combined with Sunitinib.
Gemcitabine Injection	Gemcitabine Injection The risk or severity of adverse effects can be increased when Gemcitabine is combined with Sunitinib.
Indinavir	Indinavir The metabolism of Sunitinib can be decreased when combined with Indinavir.
Ritonavir	Ritonavir The serum concentration of Sunitinib can be increased when it is combined with Ritonavir.
Docetaxel Injection	Docetaxel Injection The metabolism of Sunitinib can be decreased when combined with Docetaxel.
Clomipramine	Clomipramine The metabolism of Sunitinib can be decreased when combined with Clomipramine.
Zafirlukast	Zafirlukast The metabolism of Sunitinib can be decreased when combined with Zafirlukast.
Mirtazapine	Mirtazapine The risk or severity of QTc prolongation and torsade de pointes can be increased when Sunitinib is combined with Mirtazapine.
Topiramate	Topiramate The metabolism of Sunitinib can be increased when combined with Topiramate.
Insulin Lispro Injection	Insulin Lispro Injection The risk or severity of hypoglycemia can be increased when Insulin lispro is combined with Sunitinib.
Donepezil	Donepezil Sunitinib may decrease the excretion rate of Donepezil which could result in a higher serum level.
Nelfinavir	Nelfinavir The metabolism of Sunitinib can be decreased when combined with Nelfinavir.
Azithromycin	Azithromycin The metabolism of Azithromycin can be decreased when combined with Sunitinib.
Carvedilol	Carvedilol The therapeutic efficacy of Sunitinib can be increased when used in combination with Carvedilol.
Flutamide	Flutamide The metabolism of Sunitinib can be decreased when combined with Flutamide.
Selegiline	Selegiline Selegiline may increase the hypoglycemic activities of Sunitinib.
Bicalutamide	Bicalutamide The metabolism of Sunitinib can be decreased when combined with Bicalutamide.
Sertraline	Sertraline The risk or severity of hypoglycemia can be increased when Sertraline is combined with Sunitinib.
Propafenone	Propafenone The therapeutic efficacy of Sunitinib can be increased when used in combination with Propafenone.
Raloxifene	Raloxifene The metabolism of Raloxifene can be decreased when combined with Sunitinib.
Irbesartan	Irbesartan The metabolism of Sunitinib can be decreased when combined with Irbesartan.
Tamsulosin	Tamsulosin The therapeutic efficacy of Sunitinib can be increased when used in combination with Tamsulosin.
Finasteride	Finasteride The metabolism of Sunitinib can be decreased when combined with Finasteride.
Quetiapine	Quetiapine The metabolism of Sunitinib can be decreased when combined with Quetiapine.
Cetirizine	Cetirizine The risk or severity of QTc prolongation can be increased when Cetirizine is combined with Sunitinib.
Paroxetine	Paroxetine The metabolism of Sunitinib can be decreased when combined with Paroxetine.
Citalopram	Citalopram The metabolism of Citalopram can be decreased when combined with Sunitinib.
Capecitabine	Capecitabine The risk or severity of QTc prolongation can be increased when Capecitabine is combined with Sunitinib.
Efavirenz	Efavirenz The metabolism of Sunitinib can be increased when combined with Efavirenz.
Sildenafil	Sildenafil The metabolism of Sunitinib can be decreased when combined with Sildenafil.
Pioglitazone	Pioglitazone The risk or severity of hypoglycemia can be increased when Pioglitazone is combined with Sunitinib.
Trastuzumab Injection	Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Sunitinib.
Celecoxib	Celecoxib The therapeutic efficacy of Sunitinib can be increased when used in combination with Celecoxib.
Rosiglitazone	Rosiglitazone The risk or severity of hypoglycemia can be increased when Rosiglitazone is combined with Sunitinib.
Tolterodine	Tolterodine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Sunitinib.
Thalidomide	Thalidomide The risk or severity of adverse effects can be increased when Thalidomide is combined with Sunitinib.
Balsalazide	Balsalazide Balsalazide may increase the hypoglycemic activities of Sunitinib.
Nateglinide	Nateglinide The metabolism of Sunitinib can be decreased when combined with Nateglinide.
Galantamine	Galantamine The risk or severity of QTc prolongation can be increased when Galantamine is combined with Sunitinib.
Rabeprazole	Rabeprazole The metabolism of Sunitinib can be decreased when combined with Rabeprazole.
Terbinafine	Terbinafine The metabolism of Sunitinib can be increased when combined with Terbinafine.