Arnica - Aspirin, Omeprazole Interaction
Herbal: Arnica
Also Known As: American Arnica, Arctic Arnica, Arnica Flos, Arnica Flower, Arnikablüten, Bergwohlverleih, European Arnica, Foothill Arnica, Heart-Leaf Arnica, Hillside Arnica, Kraftwurz, Leopard's Bane, Mountain Arnica, Mountain Snuff, Mountain Tobacco, North American Meadow Arnica, Tw
Drug: Aspirin, Omeprazole
Brand names:
Yosprala
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 25, 2025
Interaction Details
Aspirin, Omeprazole is classified as belonging to the following category: Anticoagulant/Antiplatelet Drugs
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs. Homeopathic arnica preparations are unlikely to have this interaction.
In vitro evidence shows that sesquiterpene lactones in arnica flowers can decrease platelet aggregation. However, this effect has not been reported in humans.
Interaction Rating
Likelihood of Occurrence
UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
References
- Schroder H, Losche W, Strobach H, et al. Helenalin and 11 alpha, 13-dihydrohelenalin, two constituents from Arnica montana L., inhibit human platelet function via thiol-dependent pathways. Thromb Res 1990;57:839-45.
Arnica Overview
Arnica is a plant that is native to Europe and North America and is part of the daisy family. It is known for its yellow, daisy-like flowers and has been traditionally used in homeopathic medicine to help decrease pain, swelling, and bruising. It has also been used in topical preparations to help reduce the pain from osteoarthritis. Arnica preparations are typically standardized according to the Homeopathic Pharmacopeia of the United States. In terms of drug interactions, it is important to note that in theory, arnica might have additive effects with anticoagulant and antiplatelet drugs but homeopathic arnica preparations are unlikely to have this interaction due to the extremely low amounts used.
Aspirin, Omeprazole Overview
-
The combination of aspirin and omeprazole is used to reduce the risk of stroke or heart attack in patients who have had or are at risk of these conditions and are also at risk of developing a stomach ulcer when taking aspirin. Aspirin is in a class of medications called antiplatelet agents. It works by preventing platelets (a type of blood cell) from collecting and forming clots that may cause a heart attack or stroke. Omeprazole is in a class of medications called proton-pump inhibitors. It works by decreasing the amount of acid made in the stomach.
Arnica - More Interactions
Arnica interacts with 121 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
Ask A Pharmacist About Your Herbal Questions!
Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
Ask A Pharmacist