Interaction Details

Minocycline Hydrochloride is classified as belonging to the following category: Nephrotoxic Drugs

Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects. Aristolochic acid can damage the kidneys and is deemed unsafe by the FDA, leading to the classification of products containing it as adulterated. When considering medications that may also pose a risk of kidney damage, caution is advised when combining them with asarabacca due to potential additive nephrotoxicity. It is advisable to consult healthcare professionals before using asarabacca alongside nephrotoxic drugs to minimize the risk of adverse effects on kidney function.

Interaction Rating

Major

Likelihood of Occurrence

Possible

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists

Asarabacca Overview

Asarabacca Asarum europaeum, known as European wild ginger, is a perennial herb found in European shady woodlands. It features heart-shaped, glossy leaves and bell-shaped, brownish-purple flowers hidden beneath the foliage. Traditionally, its rhizomes are used in medicine for their aroma and sweat-inducing properties, but modern use is limited due to the presence of toxic aristolochic acid. Asarabacca is often tainted with this toxin, which is harmful to the kidneys and carcinogenic. The FDA deems all aristolochic acid-containing products unsafe and adulterated, emphasizing the need for verified aristolochic acid-free products. Asarabacca's rhizome contains phenylpropanol, trans-isoasarone, and trans-isomethyleugenol. It exhibits local anesthetic effects, potentially due to trans-isoasarone and trans-isomethyleugenol, bronchial effects possibly attributed to phenylpropanol, emetic effects likely linked to trans-isoasarone, and spasmolytic effects possibly due to trans-isoasarone.
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Minocycline Hydrochloride Overview

  • Minocycline is used to treat infections caused by bacteria including pneumonia and other respiratory tract infections; certain infections of the skin, eye, lymphatic, intestinal, genital, and urinary systems; and certain other infections that are spread by ticks, lice, mites, and infected animals. It is also used along with other medications to treat acne. Minocycline is also used to treat plague and tuleramia (serious infections that may be spread on purpose as part of a bioterror attack). It can also be used in patients who cannot be treated with penicillin to treat certain types of food poisoning, and anthrax (a serious infection that may be spread on purpose as part of a bioterror attack). It can also be used to eliminate bacteria from your nose and throat that may cause meningitis (swelling of tissues around the brain) in others, even though you may not have an infection. Minocycline extended-release tablet (Solodyn) is only used to treat acne. Minocycline is in a class of medications called tetracycline antibiotics. It works to treat infections by preventing the growth and spread of bacteria. It works to treat acne by killing the bacteria that infects pores and decreasing a certain natural oily substance that causes acne.

  • Antibiotics such as minocycline will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

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Asarabacca - More Interactions

Asarabacca interacts with 350 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

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