Avocado Soy Unsaponifiables (asu) - Provigil (Modafinil) Interaction
Herbal: Avocado Soy Unsaponifiables (asu)
Also Known As: ASU, ASU-NMX 1000TM, ASU Expanscience, Avoca ASU, Avosol, Dasuquin, Piascledine 300
Drug: Modafinil
Brand names:
Provigil, Sparlon, Alertec
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 13, 2024
Interaction Details
There were no interactions found between Modafinil and Avocado Soy Unsaponifiables (asu). This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Avocado Soy Unsaponifiables (asu) Overview
Avocado-soy-unsaponifiables (ASU) are a natural extract made from avocado and soybean oils. They are known for their anti-inflammatory properties and are commonly used to manage symptoms of osteoarthritis. ASU is believed to help reduce pain and improve joint function by inhibiting the breakdown of cartilage and promoting its repair. Additionally, ASU may have a protective effect on joint structures and help reduce the need for nonsteroidal anti-inflammatory drugs (NSAIDs).
ASU contains tocopherols, phytosterols, triterpene alcohols, and other constituents, although the exact composition can vary between products. Some products may contain citrostadienol from avocado unsaponifiables, while others may contain brassicasterol, which is not common in avocado or soy. Differences in constituents between products may be due to variations in methods of analysis or preparation. ASU has demonstrated its anti-inflammatory effects by reducing inflammatory cytokines like interleukin-17 and tumor necrosis factor-alpha, while increasing anti-inflammatory cytokines such as interleukin-4 and interleukin-10. It also decreases levels of inflammatory mediators like prostaglandin E2 and metalloproteinase.
Modafinil Overview
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Modafinil is used to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness) or shift work sleep disorder (sleepiness during scheduled waking hours and difficulty falling asleep or staying asleep during scheduled sleeping hours in people who work at night or on rotating shifts). Modafinil is also used along with breathing devices or other treatments to prevent excessive sleepiness caused by obstructive sleep apnea/hypopnea syndrome (OSAHS; a sleep disorder in which the patient briefly stops breathing or breathes shallowly many times during sleep and therefore doesn't get enough restful sleep). Modafinil is in a class of medications called wakefulness promoting agents. It works by changing the amounts of certain natural substances in the area of the brain that controls sleep and wakefulness.
Avocado Soy Unsaponifiables (asu) - More Interactions
Avocado Soy Unsaponifiables (asu) interacts with 0 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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