Banderol - Alimta (Pemetrexed) Interaction
Herbal: Banderol
Also Known As: Otoba parvifolia
Drug: Pemetrexed
Brand names:
Alimta, Pemfexy
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Feb 11, 2023
Interaction Details
Pemetrexed is classified as belonging to the following category: Organic Anion Transporter 3 (Oat3) Substrates
Small lab studies have found that Banderol may also inhibit OATP1B3 (Organic Anion Transporting Polypeptide 1B3), in addition to OATP1B1. If a drug is a substrate for both transporters, the risk of interaction with Banderol increases but the overall clinical significance is not well understood.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
Banderol Overview
Banderol is a dietary supplement manufactured by Nutramedix. It contains Otoba parvifolia bark extract. Otoba parvifolia is a species of tree in the Myristicaceae family, which is native to the Amazonian region of South America. It is also known as the "Small-leaved Otoba".
It is believed that the leaves and bark of the Otoba parvifolia tree have medicinal properties, such as anti-inflammatory properties that may help to reduce pain, swelling, and redness in the body. Additionally, the bark is thought to have antimicrobial properties, which may be effective against bacteria and fungi, including some that are resistant to antibiotics.
Pemetrexed Overview
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Pemetrexed injection is used in combination with other chemotherapy medications as a first treatment for a certain type of non-small cell lung cancer (NSCLC) that has spread to nearby tissues or to other parts of the body. Pemetrexed injection is also used alone to treat NSCLC as ongoing treatment in people who have already received certain chemotherapy medications and whose cancer has not worsened and in people who could not be treated successfully with other chemotherapy medications. Pemetrexed injection is also in combination with another chemotherapy medication as a first treatment for malignant pleural mesothelioma (a type of cancer that affects the inside lining of the chest cavity) in people who cannot be treated with surgery. Pemetrexed is in a class of medications called antifolate antineoplastic agents. It works by blocking the action of a certain substance in the body that may help cancer cells multiply.
Banderol - More Interactions
Banderol interacts with 173 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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