Boswellia Serrata - Selegiline Interaction
Herbal: Boswellia Serrata
Also Known As: Boswellia serrata, Arbre à Oliban Indien, Boswella, Boswellin, Boswellin Serrata Resin, Encens Indien, Gajabhakshya, Indian Frankincense, Oliban Indien, Salai Guggal, Salai Guggul, Sallaki Guggul, Shallaki
Drug: Selegiline
Brand names:
Carbex, Eldepryl, Emsam, Zelapar
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 09, 2024
Interaction Details
There were no interactions found between Selegiline and Boswellia Serrata. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Pharmacist Analysis
No interaction has been noted between Boswellia and the drug in question on this interaction check.
In terms of other interactions, Boswellia serrata has been shown in laboratory studies to mildly inhibit several enzymes involved in drug metabolism, including CYP1A2, CYP2C19, CYP2C9, CYP2D6, and CYP3A4. This inhibition may increase the levels of drugs metabolized by these enzymes, potentially leading to adverse effects.
However, it is important to note that this inhibition has only been seen in a lab setting, and has not been reported in humans. Whether or not Boswellia supplements have clinically significant drug interactions due to the effects on the above enzymes isn't well known. In most cases, it appears unlikely that these interactions would be clinically significant as there is a lack of reports of problems being caused in humans.
In addition, Boswellia serrata may interact with immunosuppressive drugs.
Studies show that Boswellia may help reduce the activity of some cells involved in autoimmune diseases. This could lead to a decrease in the production of antibodies and certain immune cells. However, other studies have found that certain components of Boswellia serrata may actually stimulate the immune system in certain situations. More research is needed to better understand the effect of Boswellia on immunosuppressive drugs.
- Dr. Brian Staiger, PharmDBoswellia Serrata Overview
Selegiline Overview
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Selegiline is used to help control the symptoms of Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) in people who are taking levodopa and carbidopa combination (Sinemet). Selegiline may help people with Parkinson's disease by decreasing the dose of levodopa/carbidopa needed to control symptoms, stopping the effects of levodopa/carbidopa from wearing off between doses, and increasing the length of time that levodopa/carbidopa will continue to control symptoms. Selegiline is in a group of medications called monoamine oxidase type B (MAO-B) inhibitors. It works by increasing the amount of dopamine (a natural substance that is needed to control movement) in the brain.
Boswellia Serrata - More Interactions
Boswellia Serrata interacts with 920 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.