Coenzyme Q10 - Aspirin Interaction

Interaction Details

Pharmacist Analysis

Although CoQ10 is considered relatively safe for most individuals, it does have some reported interactions that are important to be aware of.

This includes:

• Antihypertensives: Clinical research has shown that CoQ10 can significantly lower blood pressure but conflicting results have been reported.

• Warfarin: Research is conflicting but concomitant use of CoQ10 and warfarin might reduce the anticoagulant effects of warfarin.

• Alkylating Agents: Antioxidants such as CoQ10 might also protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy.

Outside of the interactions I've listed above, CoQ10 is generally considered safe to supplement with in most situations.

In fact, some individuals taking certain medications (e.g., 'Statins') may be recommended to take it.

If you have any questions about CoQ10 supplements, be sure to speak to your healthcare professional. We are always happy to answer questions on the matter as well!

Safe With Aspirin?

While CoQ10 has been reported to potentially have interactions with the anticoagulant warfarin (which we've discussed on that particular interaction page), CoQ10 itself is not known to have any significant effects on blood coagulation.

In fact, there is some evidence to suggest that CoQ10 may have a potential role in reducing the risk of bleeding associated with aspirin therapy.

A randomized, double-blind, placebo-controlled trial published in the American Journal of Cardiology in 2014 noted the potential that CoQ10 supplementation has in reducing the risk of gastrointestinal bleeding in patients taking low-dose aspirin, although it wasn't specifically evaluated in this regard.

Overall, CoQ10 is considered safe to take with aspirin for most individuals, but it is important to talk to your doctor before starting any new medications or supplements.

Aspirin Overview

• Aspirin rectal is used to reduce fever and to relieve mild to moderate pain from headaches, menstrual periods, arthritis, toothaches, and muscle aches. Aspirin is in a group of medications called salicylates. It works by stopping the production of certain natural substances that cause fever, pain, swelling, and blood clots.

Coenzyme Q10 - More Interactions

Coenzyme Q10 interacts with 195 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.