Interaction Details

There were no interactions found between Fenofibrate and Creatine. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Fenofibrate and Creatine? Ask Dr. Brian Staiger about it by contacting him directly.

Creatine Overview

Creatine Creatine is an organic amine that occurs naturally in the body and is also found in certain foods, such as meat and fish. It is stored mostly in the skeletal muscles, where it is used to generate energy during physical activity. Creatine is a popular over-the-counter dietary supplement, and some evidence suggests it is effective at improving exercise performance, particularly during high-intensity activities such as weightlifting and sprinting. However, the degree to which creatine supplements may improve exercise performance can vary depending on the individual and the type of physical activity being performed Creatine is generally well-tolerated but may cause some minor side effects, such as cramping and water retention in some individuals. Long-term use has been rarely linked to kidney problems, but its use is generally regarded as safe. There are several different forms of creatine available, with the most common form being monohydrate salt. Other salt forms, including di-creatine citrate and 'pH buffered' creatine, are also available.
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Fenofibrate Overview

  • Fenofibrate is used with a low-fat diet, exercise, and sometimes with other medications to reduce the amounts of fatty substances such as cholesterol and triglycerides in the blood and to increase the amount of HDL (high-density lipoprotein; a type of fatty substance that decreases the risk of heart disease) in the blood. Build-up of cholesterol and fats along the walls of the arteries (a process known as atherosclerosis) decreases the blood flow and, therefore, the oxygen supply to the heart, brain, and other parts of the body. This increases the risk of heart disease, angina (chest pain), strokes, and heart attacks. Although fenofibrate decreases the levels of fatty substances in the blood, it has not been shown to decrease the risk of heart attacks or strokes. Fenofibrate is in a class of medications called antilipemic agents. It works by speeding the natural processes that remove cholesterol from the body.

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Creatine - More Interactions

Creatine interacts with 0 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

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Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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