Interaction Details

Alogliptin, Metformin is classified as belonging to the following category: Antidiabetes Drugs

Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
In people with type 2 diabetes, including those taking oral hypoglycemic medications, DHA seems to increase fasting blood glucose levels.

Interaction Rating


Likelihood of Occurrence


Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists


  • Woodman RJ, Mori TA, Burke V, et al. Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension. Am J Clin Nutr 2002;76:1007-15..

Docosahexaenoic Acid (dha) Overview

Docosahexaenoic Acid (dha) DHA (docosahexaenoic acid) is an omega-3 fatty acid that is important for the proper functioning of the nervous system and eyes. DHA can be found in a variety of foods and in abundance in many different types of fatty fish, such as salmon and mackerel. It is a popular dietary supplement, consistently among the most utilized. There is some evidence to suggest that DHA may have a number of potential health benefits, including improving cognitive function and reducing the risk of age-related cognitive decline. It has also been shown to be important for fetal and infant brain development and is a common component in prenatal vitamins. DHA is often combined with EPA (eicosapentaenoic acid) in dietary supplements and both are found together in most fish-sourced ones. One main difference between DHA and EPA is their structure. DHA is a long-chain fatty acid, while EPA is a medium-chain fatty acid. This difference in structure may affect how they are utilized in the body and their potential health benefits. For example, DHA is more highly concentrated in the brain and is believed to be important for brain and eye health, while EPA is more highly concentrated in the heart and may be helpful in reducing inflammation and improving cardiovascular health.

Docosahexaenoic Acid (dha) - More Interactions

Docosahexaenoic Acid (dha) interacts with 366 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

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